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Jan Holmgren
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57
Czerkinsky, Cecil
55
Svennerholm, Ann-Mari
24
Eriksson, Kristina
23
Sun, Jia-Bin
20
Lindblad, Marianne
19
Nordström, Inger
14
Sack, David
14
Lycke, Nils
14
Jertborn, Marianne
14
Harandi, Ali
12
Fredriksson, Margareta
11
Li, Bin-Ling
9
Kilander, Anders
9
Lebens, Michael
9
Raghavan, Sukanya
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All Publications
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2009: Attridge Stephen R; Holmgren Jan
Vibrio cholerae O139 capsular polysaccharide confers complement resistance in the absence or presence of antibody yet presents a productive target for cell lysis: implications for detection of bactericidal antibodies.
Microbial pathogenesis 2009;47(6):314-20.
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2009: Sur Dipika; Lopez Anna Lena; Kanungo Suman; Paisley Allison; Manna Byomkesh; Ali Mohammad; Niyogi Swapan K; Park Jin Kyung; Sarkar Banawarilal; Puri Mahesh K; Kim Deok Ryun; Deen Jacqueline L; Holmgren Jan; Carbis Rodney; Rao Raman; Nguyen Thu Van; Donner Allan; Ganguly Nirmal K; Nair G Balakrish; Bhattacharya Sujit K; Clemens John D
Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: an interim analysis of a cluster-randomised, double-blind, placebo-controlled trial.
Lancet 2009;374(9702):1694-702.
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2009: Kanungo Suman; Paisley Allison; Lopez Anna Lena; Bhattacharya Mihir; Manna Byomkesh; Kim Deok Ryun; Han Seung Hyun; Attridge Stephen; Carbis Rodney; Rao Raman; Holmgren Jan; Clemens John D; Sur Dipika
Immune responses following one and two doses of the reformulated, bivalent, killed, whole-cell, oral cholera vaccine among adults and children in Kolkata, India: a randomized, placebo-controlled trial.
Vaccine 2009;27(49):6887-93.
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2009: Fahlén-Yrlid Linda; Gustafsson Tobias; Westlund Jessica; Holmberg Anna; Strömbeck Anna; Blomquist Margareta; MacPherson Gordon G; Holmgren Jan; Yrlid Ulf
CD11c(high )dendritic cells are essential for activation of CD4+ T cells and generation of specific antibodies following mucosal immunization.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(8):5032-41.
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2009: Nygren E; Li B-L; Holmgren J; Attridge S R
Establishment of an adult mouse model for direct evaluation of the efficacy of vaccines against Vibrio cholerae.
Infection and immunity 2009;77(8):3475-84.
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2009: Shamsuzzaman Sohel; Ahmed Tanvir; Mannoor Kaiissar; Begum Yasmin Ara; Bardhan Pradip Kumar; Sack R Bradley; Sack David A; Svennerholm Ann-Mari; Holmgren Jan; Qadri Firdausi
Robust gut associated vaccine-specific antibody-secreting cell responses are detected at the mucosal surface of Bangladeshi subjects after immunization with an oral killed bivalent V. cholerae O1/O139 whole cell cholera vaccine: comparison with other mucosal and systemic responses.
Vaccine 2009;27(9):1386-92.
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2009: Attridge S R; Wallerström G; Li B-L; Morona R; Holmgren J
Differential immunogenicity of Vibrio cholerae O139 variants expressing different combinations of naturally occurring and atypical forms of the serogroup polysaccharide.
Vaccine 2009;27(7):1055-61.
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2008: Sun Jia-Bin; Flach Carl-Fredrik; Czerkinsky Cecil; Holmgren Jan
B lymphocytes promote expansion of regulatory T cells in oral tolerance: powerful induction by antigen coupled to cholera toxin B subunit.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(12):8278-87.
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2008: Nygren Erik; Holmgren Jan; Attridge Stephen R
Murine antibody responses following systemic or mucosal immunization with viable or inactivated Vibrio cholerae.
Vaccine 2008;26(52):6784-90.
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2008: Nowroozalizadeh Salma; Jansson Marianne; Adamsson Jenni; Lindblad Marianne; Fenyö Eva-Maria; Holmgren Jan; Harandi Ali M
Suppression of HIV replication in vitro by CpG and CpG conjugated to the non toxic B subunit of cholera toxin.
Current HIV research 2008;6(3):230-8.
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2008: Ali Mohammad; Emch Michael; Yunus Mohammad; Sack David; Lopez Anna Lena; Holmgren Jan; Clemens John
Vaccine Protection of Bangladeshi infants and young children against cholera: implications for vaccine deployment and person-to-person transmission.
The Pediatric infectious disease journal 2008;27(1):33-7.
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2008: Mahalanabis Dilip; Lopez Anna Lena; Sur Dipika; Deen Jacqueline; Manna Byomkesh; Kanungo Suman; von Seidlein Lorenz; Carbis Rodney; Han Seung Hyun; Shin Seong Hye; Attridge Stephen; Rao Raman; Holmgren Jan; Clemens John; Bhattacharya Sujit K
A randomized, placebo-controlled trial of the bivalent killed, whole-cell, oral cholera vaccine in adults and children in a cholera endemic area in Kolkata, India.
PloS one 2008;3(6):e2323.
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2007: Cuburu Nicolas; Kweon Mi-Na; Song Joo-Hye; Hervouet Catherine; Luci Carmelo; Sun Jia-Bin; Hofman Paul; Holmgren Jan; Anjuère Fabienne; Czerkinsky Cecil
Sublingual immunization induces broad-based systemic and mucosal immune responses in mice.
Vaccine 2007;25(51):8598-610.
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2007: Thiem Vu Dinh; Canh Do Gia; Anh Dang Duc; Deen Jacqueline L; von Seidlein Lorenz; Clemens John D; Holmgren Jan
Response to "questionable merits of the field trial of an oral killed whole cell cholera vaccine in Vietnam during 1998-2003" Vaccine 2007;25(8):1353-4.
Vaccine 2007;25(47):7981-3.
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2007: Sun J-B; Czerkinsky C; Holmgren J
Sublingual 'oral tolerance' induction with antigen conjugated to cholera toxin B subunit generates regulatory T cells that induce apoptosis and depletion of effector T cells.
Scandinavian journal of immunology 2007;66(2-3):278-86.
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2007: Flach Carl-Fredrik; Qadri Firdausi; Bhuiyan Taufiqur R; Alam Nur H; Jennische Eva; Holmgren Jan; Lönnroth Ivar
Differential expression of intestinal membrane transporters in cholera patients.
FEBS letters 2007;581(17):3183-8.
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2007: Flach Carl-Fredrik; Qadri Firdausi; Bhuiyan Taufiqur R; Alam Nur H; Jennische Eva; Lönnroth Ivar; Holmgren Jan
Broad up-regulation of innate defense factors during acute cholera.
Infection and immunity 2007;75(5):2343-50.
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2007: Anh Dang Duc; Canh Do Gia; Lopez Anna Lena; Thiem Vu Dinh; Long Phan Thi; Son Nguyen Hong; Deen Jacqueline; von Seidlein Lorenz; Carbis Rodney; Han Seung Hyun; Shin Seong Hye; Attridge Stephen; Holmgren Jan; Clemens John
Safety and immunogenicity of a reformulated Vietnamese bivalent killed, whole-cell, oral cholera vaccine in adults.
Vaccine 2007;25(6):1149-55.
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2006: Sun Jia-Bin; Raghavan Sukanya; Sjöling Asa; Lundin Samuel; Holmgren Jan
Oral tolerance induction with antigen conjugated to cholera toxin B subunit generates both Foxp3+CD25+ and Foxp3-CD25- CD4+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(11):7634-44.
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2006: Nair G Balakrish; Qadri Firdausi; Holmgren Jan; Svennerholm Ann-Mari; Safa Ashrafus; Bhuiyan Nurul A; Ahmad Q Shafi; Faruque Shah M; Faruque A S G; Takeda Yoshifumi; Sack David A
Cholera due to altered El Tor strains of Vibrio cholerae O1 in Bangladesh.
Journal of clinical microbiology 2006;44(11):4211-3.
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2006: Sun J-B; Cuburu N; Blomquist M; Li B-L; Czerkinsky C; Holmgren J
Sublingual tolerance induction with antigen conjugated to cholera toxin B subunit induces Foxp3+CD25+CD4+ regulatory T cells and suppresses delayed-type hypersensitivity reactions.
Scandinavian journal of immunology 2006;64(3):251-9.
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2006: George Chandy Annie; Hultkrantz Susanne; Raghavan Sukanya; Czerkinsky Cecil; Lebens Michael; Telemo Esbjörn; Holmgren Jan
Oral tolerance induction by mucosal administration of cholera toxin B-coupled antigen involves T-cell proliferation in vivo and is not affected by depletion of CD25+ T cells.
Immunology 2006;118(3):311-20.
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2006: Stephenson Iain; Zambon Maria C; Rudin Anna; Colegate Anthony; Podda Audino; Bugarini Roberto; Del Giudice Giusseppe; Minutello Ada; Bonnington Susan; Holmgren Jan; Mills Kingston H G; Nicholson Karl G
Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers.
Journal of virology 2006;80(10):4962-70.
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2006: Thiem Vu Dinh; Deen Jacqueline L; von Seidlein Lorenz; Canh Do Gia; Anh Dang Duc; Park Jin-Kyung; Ali Mohammad; Danovaro-Holliday M Carolina; Son Nguyen Dinh; Hoa Nguyen Thai; Holmgren Jan; Clemens John D
Long-term effectiveness against cholera of oral killed whole-cell vaccine produced in Vietnam.
Vaccine 2006;24(20):4297-303.
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2006: Harandi Ali M; Holmgren Jan
CpG oligodeoxynucleotides and mobilization of innate mucosal immunity: tasks and tactics.
Vaccine 2006;24 Suppl 2():S2-48-9.
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2006: Adamsson Jenni; Lindblad Marianne; Lundqvist Annika; Kelly Denise; Holmgren Jan; Harandi Ali M
Novel immunostimulatory agent based on CpG oligodeoxynucleotide linked to the nontoxic B subunit of cholera toxin.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4902-13.
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2006: Luci Carmelo; Hervouet Catherine; Rousseau Déborah; Holmgren Jan; Czerkinsky Cecil; Anjuère Fabienne
Dendritic cell-mediated induction of mucosal cytotoxic responses following intravaginal immunization with the nontoxic B subunit of cholera toxin.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):2749-57.
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2005: Tengvall Sara; Josefsson Agnetha; Holmgren Jan; Harandi Ali M
CpG oligodeoxynucleotide augments HSV-2 glycoprotein D DNA vaccine efficacy to generate T helper 1 response and subsequent protection against primary genital herpes infection in mice.
Journal of reproductive immunology 2005;68(1-2):53-69.
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2005: Flach Carl-Fredrik; Lange Stefan; Jennische Eva; Lönnroth Ivar; Holmgren Jan
Cholera toxin induces a transient depletion of CD8+ intraepithelial lymphocytes in the rat small intestine as detected by microarray and immunohistochemistry.
Infection and immunity 2005;73(9):5595-602.
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2005: Sánchez Joaquín; Holmgren Jan
Virulence factors, pathogenesis and vaccine protection in cholera and ETEC diarrhea.
Current opinion in immunology 2005;17(4):388-98.
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2005: Ali Mohammad; Emch Michael; von Seidlein Lorenz; Yunus Mohammad; Sack David A; Rao Malla; Holmgren Jan; Clemens John D
Herd immunity conferred by killed oral cholera vaccines in Bangladesh: a reanalysis.
Lancet 2005;366(9479):44-9.
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2005: Raghavan Sukanya; Holmgren Jan
CD4+CD25+ suppressor T cells regulate pathogen induced inflammation and disease.
FEMS immunology and medical microbiology 2005;44(2):121-7.
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2005: Holmgren Jan; Czerkinsky Cecil
Mucosal immunity and vaccines.
Nature medicine 2005;11(4 Suppl):S45-53.
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2005: Holmgren Jan; Adamsson Jenni; Anjuère Fabienne; Clemens John; Czerkinsky Cecil; Eriksson Kristina; Flach Carl-Fredrik; George-Chandy Annie; Harandi Ali M; Lebens Michael; Lehner Thomas; Lindblad Marianne; Nygren Erik; Raghavan Sukanya; Sanchez Joaquin; Stanford Michael; Sun Jia-Bin; Svennerholm Ann-Mari; Tengvall Sara
Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin, cholera toxin B subunit and CpG DNA.
Immunology letters 2005;97(2):181-8.
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2005: Yun Cheol H; Lundgren Anna; Azem Josef; Sjöling Asa; Holmgren Jan; Svennerholm Ann-Mari; Lundin B Samuel
Natural killer cells and Helicobacter pylori infection: bacterial antigens and interleukin-12 act synergistically to induce gamma interferon production.
Infection and immunity 2005;73(3):1482-90.
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2004: Anjuère Fabienne; Luci Carmelo; Lebens Michael; Rousseau Déborah; Hervouet Catherine; Milon Geneviève; Holmgren Jan; Ardavin Carlos; Czerkinsky Cecil
In vivo adjuvant-induced mobilization and maturation of gut dendritic cells after oral administration of cholera toxin.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):5103-11.
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2004: Raghavan S; Suri-Payer E; Holmgren J
Antigen-specific in vitro suppression of murine Helicobacter pylori-reactive immunopathological T cells by CD4CD25 regulatory T cells.
Scandinavian journal of immunology 2004;60(1-2):82-8.
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2004: Sun J-B; Eriksson K; Li B-L; Lindblad M; Azem J; Holmgren J
Vaccination with dendritic cells pulsed in vitro with tumor antigen conjugated to cholera toxin efficiently induces specific tumoricidal CD8+ cytotoxic lymphocytes dependent on cyclic AMP activation of dendritic cells.
Clinical immunology (Orlando, Fla.) 2004;112(1):35-44.
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2004: Stanford M; Whittall T; Bergmeier L A; Lindblad M; Lundin S; Shinnick T; Mizushima Y; Holmgren J; Lehner T
Oral tolerization with peptide 336-351 linked to cholera toxin B subunit in preventing relapses of uveitis in Behcet's disease.
Clinical and experimental immunology 2004;137(1):201-8.
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2004: Clemens John; Savarino Stephen; Abu-Elyazeed Remon; Safwat Mohammad; Rao Malla; Wierzba Thomas; Svennerholm Ann-Marie; Holmgren Jan; Frenck Robert; Park Eunsik; Naficy Abdollah
Development of pathogenicity-driven definitions of outcomes for a field trial of a killed oral vaccine against enterotoxigenic Escherichia coli in Egypt: application of an evidence-based method.
The Journal of infectious diseases 2004;189(12):2299-307.
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2004: Lebens Michael; Sun Jia-Bin; Czerkinsky Cecil; Holmgren Jan
Current status and future prospects for a vaccine against schistosomiasis.
Expert review of vaccines 2004;3(3):315-28.
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2004: Eriksson Kristina; Sun Jia-Bin; Nordström Inger; Fredriksson Margareta; Lindblad Marianne; Li Bin-Ling; Holmgren Jan
Coupling of antigen to cholera toxin for dendritic cell vaccination promotes the induction of MHC class I-restricted cytotoxic T cells and the rejection of a cognate antigen-expressing model tumor.
European journal of immunology 2004;34(5):1272-81.
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2004: Sánchez Joaquín; Medina Gerardo; Buhse Thomas; Holmgren Jan; Soberón-Chavez Gloria
Expression of cholera toxin under non-AKI conditions in Vibrio cholerae El Tor induced by increasing the exposed surface of cultures.
Journal of bacteriology 2004;186(5):1355-61.
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2004: Harandi Ali M; Holmgren Jan
CpG DNA as a potent inducer of mucosal immunity: implications for immunoprophylaxis and immunotherapy of mucosal infections.
Current opinion in investigational drugs (London, England : 2000) 2004;5(2):141-5.
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2003: Raghavan S; Nyström J; Fredriksson M; Holmgren J; Harandi A M
Orally administered CpG oligodeoxynucleotide induces production of CXC and CC chemokines in the gastric mucosa and suppresses bacterial colonization in a mouse model of Helicobacter pylori infection.
Infection and immunity 2003;71(12):7014-22.
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2003: Raghavan S; Fredriksson M; Svennerholm A-M; Holmgren J; Suri-Payer E
Absence of CD4+CD25+ regulatory T cells is associated with a loss of regulation leading to increased pathology in Helicobacter pylori-infected mice.
Clinical and experimental immunology 2003;132(3):393-400.
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2003: Holmgren Jan; Czerkinsky Cecil; Eriksson Kristina; Mharandi Ali
Mucosal immunisation and adjuvants: a brief overview of recent advances and challenges.
Vaccine 2003;21 Suppl 2():S89-95.
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2003: Holmgren Jan; Harandi Ali M; Czerkinsky Cecil
Mucosal adjuvants and anti-infection and anti-immunopathology vaccines based on cholera toxin, cholera toxin B subunit and CpG DNA.
Expert review of vaccines 2003;2(2):205-17.
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2003: Eriksson Kristina; Fredriksson Margareta; Nordström Inger; Holmgren Jan
Cholera toxin and its B subunit promote dendritic cell vaccination with different influences on Th1 and Th2 development.
Infection and immunity 2003;71(4):1740-7.
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2003: Harandi Ali M; Sanchez Joaquin; Eriksson Kristina; Holmgren Jan
Recent developments in mucosal immunomodulatory adjuvants.
Current opinion in investigational drugs (London, England : 2000) 2003;4(2):156-61.
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2003: Anjuère Fabienne; George-Chandy Annie; Audant Florence; Rousseau Déborah; Holmgren Jan; Czerkinsky Cecil
Transcutaneous immunization with cholera toxin B subunit adjuvant suppresses IgE antibody responses via selective induction of Th1 immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(3):1586-92.
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2003: Phipps Paula A; Stanford Miles R; Sun Jia-Bin; Xiao Bao-Guo; Holmgren Jan; Shinnick Thomas; Hasan Adam; Mizushima Yutaka; Lehner Thomas
Prevention of mucosally induced uveitis with a HSP60-derived peptide linked to cholera toxin B subunit.
European journal of immunology 2003;33(1):224-32.
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2003: Lebens Michael; Sun Jia-Bin; Sadeghi Hamid; Bäckström Malin; Olsson Ida; Mielcarek Nathalie; Li Bin-Ling; Capron Andre; Czerkinsky Cecil; Holmgren Jan
A mucosally administered recombinant fusion protein vaccine against schistosomiasis protecting against immunopathology and infection.
Vaccine 2003;21(5-6):514-20.
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2003: Harandi Ali M; Eriksson Kristina; Holmgren Jan
A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection.
Journal of virology 2003;77(2):953-62.
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2003: Lehner T; Stanford M R; Phipps P A; Sun J B; Xiao B G; Holmgren J; Shinnick T; Hasan A; Mizushima Y
Immunopathogenesis and prevention of uveitis with the Behçet's disease-specific peptide linked to cholera toxin B.
Advances in experimental medicine and biology 2003;528():173-80.
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2002: Raghavan S; Hjulström M; Holmgren J; Svennerholm A-M
Protection against experimental Helicobacter pylori infection after immunization with inactivated H. pylori whole-cell vaccines.
Infection and immunity 2002;70(11):6383-8.
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2002: Eriksson Kristina; Holmgren Jan
Recent advances in mucosal vaccines and adjuvants.
Current opinion in immunology 2002;14(5):666-72.
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2002: Sánchez Joaquín; Wallerström Gun; Fredriksson Margareta; Angström Jonas; Holmgren Jan
Detoxification of cholera toxin without removal of its immunoadjuvanticity by the addition of (STa-related) peptides to the catalytic subunit. A potential new strategy to generate immunostimulants for vaccination.
The Journal of biological chemistry 2002;277(36):33369-77.
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2002: Hernandez Hector J; Rutitzky Laura I; Lebens Mike; Holmgren Jan; Stadecker Miguel J
Diminished immunopathology in Schistosoma mansoni infection following intranasal administration of cholera toxin B-immunodominant peptide conjugate correlates with enhanced transforming growth factor-beta production by CD4 T cells.
Parasite immunology 2002;24(8):423-7.
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2002: Raghavan S; Svennerholm A-M; Holmgren J
Effects of oral vaccination and immunomodulation by cholera toxin on experimental Helicobacter pylori infection, reinfection, and gastritis.
Infection and immunity 2002;70(8):4621-7.
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2002: Sadeghi Hamid; Bregenholt Søren; Wegmann Dale; Petersen Jacob S; Holmgren Jan; Lebens Michael
Genetic fusion of human insulin B-chain to the B-subunit of cholera toxin enhances in vitro antigen presentation and induction of bystander suppression in vivo.
Immunology 2002;106(2):237-45.
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2002: Trach D D; Cam P D; Ke N T; Rao M R; Dinh D; Hang P V; Hung N V; Canh D G; Thiem V D; Naficy A; Ivanoff B; Svennerholm A-M; Holmgren J; Clemens J D
Investigations into the safety and immunogenicity of a killed oral cholera vaccine developed in Viet Nam.
Bulletin of the World Health Organization 2002;80(1):2-8.
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2001: Harandi A M; Svennerholm B; Holmgren J; Eriksson K
Protective vaccination against genital herpes simplex virus type 2 (HSV-2) infection in mice is associated with a rapid induction of local IFN-gamma-dependent RANTES production following a vaginal viral challenge.
American journal of reproductive immunology (New York, N.Y. : 1989) 2001;46(6):420-4.
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2001: Johansson E L; Wassén L; Holmgren J; Jertborn M; Rudin A
Nasal and vaginal vaccinations have differential effects on antibody responses in vaginal and cervical secretions in humans.
Infection and immunity 2001;69(12):7481-6.
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2001: Sun J B; Stadecker M J; Mielcarek N; Lakew M; Li B L; Hernandez H J; Czerkinsky C; Holmgren J
Nasal administration of Schistosoma mansoni egg antigen-cholera B subunit conjugate suppresses hepatic granuloma formation and reduces mortality in S. mansoni-infected mice.
Scandinavian journal of immunology 2001;54(5):440-7.
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2001: Quiding-Järbrink M; Lönroth H; Ahlstedt I; Holmgren J; Svennerholm A M
Human gastric B cell responses can be induced by intestinal immunisation.
Gut 2001;49(4):512-8.
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2001: George-Chandy A; Eriksson K; Lebens M; Nordström I; Schön E; Holmgren J
Cholera toxin B subunit as a carrier molecule promotes antigen presentation and increases CD40 and CD86 expression on antigen-presenting cells.
Infection and immunity 2001;69(9):5716-25.
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2001: Harandi A M; Svennerholm B; Holmgren J; Eriksson K
Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of acquired gamma interferon-mediated protective immunity.
Journal of virology 2001;75(14):6705-9.
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2001: Naficy A B; Trach D D; Ke N T; Chuc N T; Sorkin A; Rao M R; Sy T H; Thiem V D; Canh D G; Mahoney R T; Holmgren J; Ivanoff B; Clemens J D
Cost of immunization with a locally produced, oral cholera vaccine in Viet Nam.
Vaccine 2001;19(27):3720-5.
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2001: Jertborn M; Nordström I; Kilander A; Czerkinsky C; Holmgren J
Local and systemic immune responses to rectal administration of recombinant cholera toxin B subunit in humans.
Infection and immunity 2001;69(6):4125-8.
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2001: George-Chandy A; Mielcarek N; Nordström I; Holmgren J; Eriksson K
Vaccination with Bordetella pertussis-pulsed autologous or heterologous dendritic cells induces a mucosal antibody response in vivo and protects against infection.
Infection and immunity 2001;69(6):4120-4.
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2001: Shen X; Lagergård T; Yang Y; Lindblad M; Fredriksson M; Wallerström G; Holmgren J
Effect of pre-existing immunity for systemic and mucosal immune responses to intranasal immunization with group B Streptococcus type III capsular polysaccharide-cholera toxin B subunit conjugate.
Vaccine 2001;19(25-26):3360-8.
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2001: Schön E; Harandi A M; Nordström I; Holmgren J; Eriksson K
Dendritic cell vaccination protects mice against lethality caused by genital herpes simplex virus type 2 infection.
Journal of reproductive immunology 2001;50(2):87-104.
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2001: Harandi A M; Svennerholm B; Holmgren J; Eriksson K
Differential roles of B cells and IFN-gamma-secreting CD4(+) T cells in innate and adaptive immune control of genital herpes simplex virus type 2 infection in mice.
The Journal of general virology 2001;82(Pt 4):845-53.
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2001: Mielcarek N; Hörnquist E H; Johansson B R; Locht C; Abraham S N; Holmgren J
Interaction of Bordetella pertussis with mast cells, modulation of cytokine secretion by pertussis toxin.
Cellular microbiology 2001;3(3):181-8.
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2001: Shen X; Lagergård T; Yang Y; Lindblad M; Fredriksson M; Holmgren J
Group B Streptococcus capsular polysaccharide-cholera toxin B subunit conjugate vaccines prepared by different methods for intranasal immunization.
Infection and immunity 2001;69(1):297-306.
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2001: Sun J B; Li B L; Lakew M; Grzych J M; Capron A; Czerkinsky C; Holmgren J
Nasal administration of Schistosoma mansoni egg antigens-cholera toxin B subunit conjugate to infected mice reduces immunopathology and mortality.
Advances in experimental medicine and biology 2001;495():305-9.
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2001: Li B L; Sun J B; Holmgren J
Adoptive transfer of mucosal T cells or dendritic cells from animals fed with cholera toxin B subunit alloantigen conjugate induces allogeneic T cell tolerance.
Advances in experimental medicine and biology 2001;495():271-5.
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2000: Shen X; Lagergård T; Yang Y; Lindblad M; Fredriksson M; Holmgren J
Preparation and preclinical evaluation of experimental group B streptococcus type III polysaccharide-cholera toxin B subunit conjugate vaccine for intranasal immunization.
Vaccine 2000;19(7-8):850-61.
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2000: Sun J B; Li B L; Czerkinsky C; Holmgren J
Enhanced immunological tolerance against allograft rejection by oral administration of allogeneic antigen linked to cholera toxin B subunit.
Clinical immunology (Orlando, Fla.) 2000;97(2):130-9.
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2000: Sun J B; Xiao B G; Lindblad M; Li B L; Link H; Czerkinsky C; Holmgren J
Oral administration of cholera toxin B subunit conjugated to myelin basic protein protects against experimental autoimmune encephalomyelitis by inducing transforming growth factor-beta-secreting cells and suppressing chemokine expression.
International immunology 2000;12(10):1449-57.
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2000: Qadri F; Asaduzzaman M; Wennerås C; Mohi G; Albert M J; Abdus Salam M; Sack R B; Jertborn M; McGhee J R; Sack D A; Holmgren J
Enterotoxin-specific immunoglobulin E responses in humans after infection or vaccination with diarrhea-causing enteropathogens.
Infection and immunity 2000;68(10):6077-81.
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2000: Shen X; Lagergård T; Yang Y; Lindblad M; Fredriksson M; Holmgren J
Systemic and mucosal immune responses in mice after mucosal immunization with group B streptococcus type III capsular polysaccharide-cholera toxin B subunit conjugate vaccine.
Infection and immunity 2000;68(10):5749-55.
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2000: Eriksson K; Nordström I; Czerkinsky C; Holmgren J
Differential effect of cholera toxin on CD45RA+ and CD45RO+ T cells: specific inhibition of cytokine production but not proliferation of human naive T cells.
Clinical and experimental immunology 2000;121(2):283-8.
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2000: Rask C; Holmgren J; Fredriksson M; Lindblad M; Nordström I; Sun J B; Czerkinsky C
Prolonged oral treatment with low doses of allergen conjugated to cholera toxin B subunit suppresses immunoglobulin E antibody responses in sensitized mice.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(7):1024-32.
-
2000: Rask C; Fredriksson M; Lindblad M; Czerkinsky C; Holmgren J
Mucosal and systemic antibody responses after peroral or intranasal immunization: effects of conjugation to enterotoxin B subunits and/or of co-administration with free toxin as adjuvant.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2000;108(3):178-86.
-
2000: Angström J; Bäckström M; Berntsson A; Karlsson N; Holmgren J; Karlsson K A; Lebens M; Teneberg S
Novel carbohydrate binding site recognizing blood group A and B determinants in a hybrid of cholera toxin and Escherichia coli heat-labile enterotoxin B-subunits.
The Journal of biological chemistry 2000;275(5):3231-8.
-
2000: Mielcarek N; Nordström I; Menozzi F D; Locht C; Holmgren J
Genital antibody responses in mice after intranasal infection with an attenuated candidate vector strain of Bordetella pertussis.
Infection and immunity 2000;68(2):485-91.
-
1999: Ploix C; Bergerot I; Durand A; Czerkinsky C; Holmgren J; Thivolet C
Oral administration of cholera toxin B-insulin conjugates protects NOD mice from autoimmune diabetes by inducing CD4+ regulatory T-cells.
Diabetes 1999;48(11):2150-6.
-
1999: Eriksson K; Quiding-Järbrink M; Osek J; Nordström I; Hjulström M; Holmgren J; Czerkinsky C
Anatomic segmentation of the intestinal immune response in nonhuman primates: differential distribution of B cells after oral and rectal immunizations to sites defined by their source of vascularization.
Infection and immunity 1999;67(11):6210-2.
-
1999: Wiedermann U; Jahn-Schmid B; Lindblad M; Rask C; Holmgren J; Kraft D; Ebner C
Suppressive versus stimulatory effects of allergen/cholera toxoid (CTB) conjugates depending on the nature of the allergen in a murine model of type I allergy.
International immunology 1999;11(10):1717-24.
-
1999: Czerkinsky C; Anjuere F; McGhee J R; George-Chandy A; Holmgren J; Kieny M P; Fujiyashi K; Mestecky J F; Pierrefite-Carle V; Rask C; Sun J B
Mucosal immunity and tolerance: relevance to vaccine development.
Immunological reviews 1999;170():197-222.
-
1999: Tarkowski A; Sun J B; Holmdahl R; Holmgren J; Czerkinsky C
Treatment of experimental autoimmune arthritis by nasal administration of a type II collagen-cholera toxoid conjugate vaccine.
Arthritis and rheumatism 1999;42(8):1628-34.
-
1999: Sun J B; Mielcarek N; Lakew M; Grzych J M; Capron A; Holmgren J; Czerkinsky C
Intranasal administration of a Schistosoma mansoni glutathione S-transferase-cholera toxoid conjugate vaccine evokes antiparasitic and antipathological immunity in mice.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):1045-52.
-
1999: Wiedermann U; Jahn-Schmid B; Lindblad M; Rask C; Holmgren J; Kraft D; Ebner C
Suppressive versus stimulatory effects of allergen/cholera toxoid (CTB) conjugates depending on the nature of the allergen in a murine model of type I allergy.
International immunology 1999;11(7):1131-8.
-
1999: Rudin A; Riise G C; Holmgren J
Antibody responses in the lower respiratory tract and male urogenital tract in humans after nasal and oral vaccination with cholera toxin B subunit.
Infection and immunity 1999;67(6):2884-90.
-
1999: Johansson E L; Rudin A; Wassén L; Holmgren J
Distribution of lymphocytes and adhesion molecules in human cervix and vagina.
Immunology 1999;96(2):272-7.
-
1999: Czerkinsky C; Sun J B; Holmgren J
Oral tolerance and anti-pathological vaccines.
Current topics in microbiology and immunology 1999;236():79-91.
-
1998: Eriksson K; Quiding-Järbrink M; Osek J; Möller A; Björk S; Holmgren J; Czerkinsky C
Specific-antibody-secreting cells in the rectums and genital tracts of nonhuman primates following vaccination.
Infection and immunity 1998;66(12):5889-96.
-
1998: Bergquist C; Lagergård T; Holmgren J
Antibody responses in serum and lung to intranasal immunization with Haemophilus influenzae type b polysaccharide conjugated to cholera toxin B subunit and tetanus toxoid.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1998;106(8):800-6.
-
1998: Rudin A; Johansson E L; Bergquist C; Holmgren J
Differential kinetics and distribution of antibodies in serum and nasal and vaginal secretions after nasal and oral vaccination of humans.
Infection and immunity 1998;66(7):3390-6.
-
1998: Johansson E L; Rask C; Fredriksson M; Eriksson K; Czerkinsky C; Holmgren J
Antibodies and antibody-secreting cells in the female genital tract after vaginal or intranasal immunization with cholera toxin B subunit or conjugates.
Infection and immunity 1998;66(2):514-20.
-
1998: Jertborn M; Ahrén C; Holmgren J; Svennerholm A M
Safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli vaccine.
Vaccine 1998;16(2-3):255-60.
-
1997: Bergquist C; Johansson E L; Lagergård T; Holmgren J; Rudin A
Intranasal vaccination of humans with recombinant cholera toxin B subunit induces systemic and local antibody responses in the upper respiratory tract and the vagina.
Infection and immunity 1997;65(7):2676-84.
-
1997: Villavedra M; Carol H; Hjulström M; Holmgren J; Czerkinsky C
"PERFEXT": a direct method for quantitative assessment of cytokine production in vivo at the local level.
Research in immunology 1997;148(4):257-66.
-
1997: Bäckström M; Shahabi V; Johansson S; Teneberg S; Kjellberg A; Miller-Podraza H; Holmgren J; Lebens M
Structural basis for differential receptor binding of cholera and Escherichia coli heat-labile toxins: influence of heterologous amino acid substitutions in the cholera B-subunit.
Molecular microbiology 1997;24(3):489-97.
-
1997: Bergquist C; Lagergård T; Holmgren J
Anticarrier immunity suppresses the antibody response to polysaccharide antigens after intranasal immunization with the polysaccharide-protein conjugate.
Infection and immunity 1997;65(5):1579-83.
-
1997: Bergerot I; Ploix C; Petersen J; Moulin V; Rask C; Fabien N; Lindblad M; Mayer A; Czerkinsky C; Holmgren J; Thivolet C
A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4610-4.
-
1997: Quiding-Järbrink M; Nordström I; Granström G; Kilander A; Jertborn M; Butcher E C; Lazarovits A I; Holmgren J; Czerkinsky C
Differential expression of tissue-specific adhesion molecules on human circulating antibody-forming cells after systemic, enteric, and nasal immunizations. A molecular basis for the compartmentalization of effector B cell responses.
The Journal of clinical investigation 1997;99(6):1281-6.
-
1996: Jertborn M; Svennerholm A M; Holmgren J
Intestinal and systemic immune responses in humans after oral immunization with a bivalent B subunit-O1/O139 whole cell cholera vaccine.
Vaccine 1996;14(15):1459-65.
-
1996: Jonson G; Osek J; Svennerholm A M; Holmgren J
Immune mechanisms and protective antigens of Vibrio cholerae serogroup O139 as a basis for vaccine development.
Infection and immunity 1996;64(9):3778-85.
-
1996: Sun J B; Rask C; Olsson T; Holmgren J; Czerkinsky C
Treatment of experimental autoimmune encephalomyelitis by feeding myelin basic protein conjugated to cholera toxin B subunit.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7196-201.
-
1996: Lebens M; Shahabi V; Bäckström M; Houze T; Lindblad N; Holmgren J
Synthesis of hybrid molecules between heat-labile enterotoxin and cholera toxin B subunits: potential for use in a broad-spectrum vaccine.
Infection and immunity 1996;64(6):2144-50.
-
1996: Holmgren J; Brantzaeg P; Capron A; Francotte M; Kilian M; Kraehenbuhl J P; Lehner T; Seljelid R
European Commission COST/STD Initiative. Report of the expert panel VI. Concerted efforts in the field of mucosal immunology.
Vaccine 1996;14(7):644-64.
-
1996: van Loon F P; Clemens J D; Chakraborty J; Rao M R; Kay B A; Sack D A; Yunus M; Ali M; Svennerholm A M; Holmgren J
Field trial of inactivated oral cholera vaccines in Bangladesh: results from 5 years of follow-up.
Vaccine 1996;14(2):162-6.
-
1996: Czerkinsky C; Sun J B; Lebens M; Li B L; Rask C; Lindblad M; Holmgren J
Cholera toxin B subunit as transmucosal carrier-delivery and immunomodulating system for induction of antiinfectious and antipathological immunity.
Annals of the New York Academy of Sciences 1996;778():185-93.
-
1995: Bckström M; Holmgren J; Schödel F; Lebens M
Characterization of an internal permissive site in the cholera toxin B-subunit and insertion of epitopes from human immunodeficiency virus-1, hepatitis B virus and enterotoxigenic Escherichia coli.
Gene 1995;165(2):163-71.
-
1995: Eriksson K; Kilander A; Hagberg L; Norkrans G; Holmgren J; Czerkinsky C
Virus-specific antibody production and polyclonal B-cell activation in the intestinal mucosa of HIV-infected individuals.
AIDS (London, England) 1995;9(7):695-700.
-
1995: Bergquist C; Lagergård T; Lindblad M; Holmgren J
Local and systemic antibody responses to dextran-cholera toxin B subunit conjugates.
Infection and immunity 1995;63(5):2021-5.
-
1995: Quiding-Järbrink M; Granström G; Nordström I; Holmgren J; Czerkinsky C
Induction of compartmentalized B-cell responses in human tonsils.
Infection and immunity 1995;63(3):853-7.
-
1995: Quiding-Järbrink M; Lakew M; Nordström I; Banchereau J; Butcher E; Holmgren J; Czerkinsky C
Human circulating specific antibody-forming cells after systemic and mucosal immunizations: differential homing commitments and cell surface differentiation markers.
European journal of immunology 1995;25(2):322-7.
-
1995: Wiedermann U; Hanson L A; Holmgren J; Dahlgren U I
Impaired mucosal immune response in vitamin A deficient rats immunized with oral cholera vaccine.
Advances in experimental medicine and biology 1995;371B():1629-31.
-
1995: Svennerholm A M; Holmgren J
Oral vaccines against cholera and enterotoxigenic Escherichia coli diarrhea.
Advances in experimental medicine and biology 1995;371B():1623-8.
-
1995: Bromander A K; Kjerrulf M; Holmgren J; Lycke N
Cholera toxin enhances antigen presentation.
Advances in experimental medicine and biology 1995;371B():1501-6.
-
1995: Lakew M; Nordström I; Quiding M; Holmgren J; Butcher E; Czerkinsky C
Phenotypic characterization of circulating antibody-secreting cells after mucosal and systemic immunizations in humans.
Advances in experimental medicine and biology 1995;371B():1451-3.
-
1995: Quiding M; Lakew M; Granström G; Nordström I; Holmgren J; Czerkinsky C
Induction of specific antibody responses in the human nasopharyngeal mucosa.
Advances in experimental medicine and biology 1995;371B():1445-50.
-
1995: Eriksson K; Kilander A; Hagberg L; Norkrans G; Holmgren J; Czerkinsky C
Intestinal immune responsiveness in HIV-infected individuals.
Advances in experimental medicine and biology 1995;371B():1011-4.
-
1994: Furuta Y; Eriksson K; Svennerholm B; Fredman P; Horal P; Jeansson S; Vahlne A; Holmgren J; Czerkinsky C
Infection of vaginal and colonic epithelial cells by the human immunodeficiency virus type 1 is neutralized by antibodies raised against conserved epitopes in the envelope glycoprotein gp120.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12559-63.
-
1994: Sun J B; Holmgren J; Czerkinsky C
Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10795-9.
-
1994: Bäckström M; Lebens M; Schödel F; Holmgren J
Insertion of a HIV-1-neutralizing epitope in a surface-exposed internal region of the cholera toxin B-subunit.
Gene 1994;149(2):211-7.
-
1994: Jertborn M; Svennerholm A M; Holmgren J
Immunological memory after immunization with oral cholera B subunit--whole-cell vaccine in Swedish volunteers.
Vaccine 1994;12(12):1078-82.
-
1994: Jonson G; Lebens M; Holmgren J
Cloning and sequencing of Vibrio cholerae mannose-sensitive haemagglutinin pilin gene: localization of mshA within a cluster of type 4 pilin genes.
Molecular microbiology 1994;13(1):109-18.
-
1994: Osek J; Jonson G; Svennerholm A M; Holmgren J
Role of antibodies against biotype-specific Vibrio cholerae pili in protection against experimental classical and El Tor cholera.
Infection and immunity 1994;62(7):2901-7.
-
1994: Lebens M; Holmgren J
Structure and arrangement of the cholera toxin genes in Vibrio cholerae O139.
FEMS microbiology letters 1994;117(2):197-202.
-
1994: Friman V; Quiding M; Czerkinsky C; Nordström I; Larsson L; Ericson D; Björkander J; Theman K; Kilander A; Holmgren J
Intestinal and circulating antibody-forming cells in IgA-deficient individuals after oral cholera vaccination.
Clinical and experimental immunology 1994;95(2):222-6.
-
1994: Holmgren J; Czerkinsky C; Lycke N; Svennerholm A M
Strategies for the induction of immune responses at mucosal surfaces making use of cholera toxin B subunit as immunogen, carrier, and adjuvant.
The American journal of tropical medicine and hygiene 1994;50(5 Suppl):42-54.
-
1994: Holmgren J
Receptors for cholera toxin and Escherichia coli heat-labile enterotoxin revisited.
Progress in brain research 1994;101():163-77.
-
1994: Lebens M; Holmgren J
Mucosal vaccines based on the use of cholera toxin B subunit as immunogen and antigen carrier.
Developments in biological standardization 1994;82():215-27.
-
1993: Lebens M; Johansson S; Osek J; Lindblad M; Holmgren J
Large-scale production of Vibrio cholerae toxin B subunit for use in oral vaccines.
Bio/technology (Nature Publishing Company) 1993;11(13):1574-8.
-
1993: Wiedermann U; Hanson L A; Holmgren J; Kahu H; Dahlgren U I
Impaired mucosal antibody response to cholera toxin in vitamin A-deficient rats immunized with oral cholera vaccine.
Infection and immunity 1993;61(9):3952-7.
-
1993: Holmgren J; Lycke N; Czerkinsky C
Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems.
Vaccine 1993;11(12):1179-84.
-
1993: Eriksson K; Kilander A; Hagberg L; Norkrans G; Holmgren J; Czerkinsky C
Intestinal antibody responses to oral vaccination in HIV-infected individuals.
AIDS (London, England) 1993;7(8):1087-91.
-
1993: Nilssen D E; Friman V; Theman K; Björkander J; Kilander A; Holmgren J; Hanson L A; Brandtzaeg P
B-cell activation in duodenal mucosa after oral cholera vaccination in IgA deficient subjects with or without IgG subclass deficiency.
Scandinavian journal of immunology 1993;38(2):201-8.
-
1993: Clemens J; Sack D; Rao M; Chakraborty J; Kay B; Ahmed F; Khan M R; van Loon F P; Svennerholm A M; Holmgren J
The design and analysis of cholera vaccine trials: recent lessons from Bangladesh.
International journal of epidemiology 1993;22(4):724-30.
-
1993: Bromander A K; Kjerrulf M; Holmgren J; Lycke N
Cholera toxin enhances alloantigen presentation by cultured intestinal epithelial cells.
Scandinavian journal of immunology 1993;37(4):452-8.
-
1993: Czerkinsky C; Svennerholm A M; Holmgren J
Induction and assessment of immunity at enteromucosal surfaces in humans: implications for vaccine development.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1993;16 Suppl 2():S106-16.
-
1993: Quiding M; Granström G; Nordström I; Ferrua B; Holmgren J; Czerkinsky C
High frequency of spontaneous interferon-gamma-producing cells in human tonsils: role of local accessory cells and soluble factors.
Clinical and experimental immunology 1993;91(1):157-63.
-
1993: Hanson L A; Telemo E; Wiedermann U; Dahlman A; Saalman R; Ahlstedt S; Friman V; Holmgren J; Czerkinsky C; Dahlgren U
Sensitization and development of tolerance via the gut.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 1993;4(3 Suppl):16-20.
-
1993: Ahrén C; Wennerås C; Holmgren J; Svennerholm A M
Intestinal antibody response after oral immunization with a prototype cholera B subunit-colonization factor antigen enterotoxigenic Escherichia coli vaccine.
Vaccine 1993;11(9):929-34.
-
1993: Jertborn M; Svennerholm A M; Holmgren J
Evaluation of different immunization schedules for oral cholera B subunit-whole cell vaccine in Swedish volunteers.
Vaccine 1993;11(10):1007-12.
-
1993: Nilssen D E; Friman V; Theman K; Björkander J; Kilander A; Holmgren J; Hanson L A; Brandtzaeg P
Intestinal immunoglobulin production after oral cholera vaccination in patients with IgA deficiency with or without IgG subclass deficiency.
Immunodeficiency 1993;4(1-4):55-7.
-
1992: Osek J; Jonson G; Svennerholm A M; Holmgren J
Enzyme-linked immunosorbent assay for determination of antibodies to Vibrio cholerae toxin-coregulated pili.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1992;100(11):1027-32.
-
1992: Osek J; Svennerholm A M; Holmgren J
Protection against Vibrio cholerae El Tor infection by specific antibodies against mannose-binding hemagglutinin pili.
Infection and immunity 1992;60(11):4961-4.
-
1992: Jonson G; Holmgren J; Svennerholm A M
Analysis of expression of toxin-coregulated pili in classical and El Tor Vibrio cholerae O1 in vitro and in vivo.
Infection and immunity 1992;60(10):4278-84.
-
1992: Lycke N; Tsuji T; Holmgren J
The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity.
European journal of immunology 1992;22(9):2277-81.
-
1992: Eriksson K; Nordström I; Horal P; Jeansson S; Svennerholm B; Vahlne A; Holmgren J; Czerkinsky C
Amplified ELISPOT assay for the detection of HIV-specific antibody-secreting cells in subhuman primates.
Journal of immunological methods 1992;153(1-2):107-13.
-
1992: Holmgren J; Czerkinsky C
Cholera as a model for research on mucosal immunity and development of oral vaccines.
Current opinion in immunology 1992;4(4):387-91.
-
1992: Holmgren J; Svennerholm A M
Bacterial enteric infections and vaccine development.
Gastroenterology clinics of North America 1992;21(2):283-302.
-
1992: Holmgren J; Czerkinsky C; Lycke N; Svennerholm A M
Mucosal immunity: implications for vaccine development.
Immunobiology 1992;184(2-3):157-79.
-
1992: Jertborn M; Svennerholm A M; Holmgren J
Safety and immunogenicity of an oral recombinant cholera B subunit-whole cell vaccine in Swedish volunteers.
Vaccine 1992;10(2):130-2.
-
1992: Holmgren J; Svennerholm A M; Jertborn M; Clemens J; Sack D A; Salenstedt R; Wigzell H
An oral B subunit: whole cell vaccine against cholera.
Vaccine 1992;10(13):911-4.
-
1992: Brezicka F T; Olling S; Bergman B; Berggren H; Engström C P; Hammarström S; Holmgren J; Larsson S; Lindholm L
Coexpression of ganglioside antigen Fuc-GM1, neural-cell adhesion molecule, carcinoembryonic antigen, and carbohydrate tumor-associated antigen CA 50 in lung cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1992;13(5-6):308-15.
-
1991: Vahlne A; Horal P; Eriksson K; Jeansson S; Rymo L; Hedström K G; Czerkinsky C; Holmgren J; Svennerholm B
Immunizations of monkeys with synthetic peptides disclose conserved areas on gp120 of human immunodeficiency virus type 1 associated with cross-neutralizing antibodies and T-cell recognition.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10744-8.
-
1991: Holmgren J
Mucosal immunity and vaccination.
FEMS microbiology immunology 1991;4(1):1-9.
-
1991: Jonson G; Holmgren J; Svennerholm A M
Identification of a mannose-binding pilus on Vibrio cholerae El Tor.
Microbial pathogenesis 1991;11(6):433-41.
-
1991: Brezicka F T; Holmgren J; Kalies I; Lindholm L
Tumor-cell killing by MAbs against fucosyl GM1, a ganglioside antigen associated with small-cell lung carcinoma.
International journal of cancer. Journal international du cancer 1991;49(6):911-8.
-
1991: Jonson G; Holmgren J; Svennerholm A M
Epitope differences in toxin-coregulated pili produced by classical and El Tor Vibrio cholerae O1.
Microbial pathogenesis 1991;11(3):179-88.
-
1991: Brezicka F T; Olling S; Bergman B; Berggren H; Engström C P; Holmgren J; Larsson S; Lindholm L
Immunohistochemical detection of two small cell lung carcinoma-associated antigens defined by MAbs F12 and 123C3 in bronchoscopy biopsy tissues.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1991;99(9):797-802.
-
1991: Löwenadler B; Lake M; Elmblad A; Holmgren E; Holmgren J; Karlström A; Svennerholm A M
A recombinant Escherichia coli heat-stable enterotoxin (STa) fusion protein eliciting anti-STa neutralizing antibodies.
FEMS microbiology letters 1991;66(3):271-7.
-
1991: Quiding M; Nordström I; Kilander A; Andersson G; Hanson L A; Holmgren J; Czerkinsky C
Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-gamma production and evokes local immunological memory.
The Journal of clinical investigation 1991;88(1):143-8.
-
1991: Bromander A; Holmgren J; Lycke N
Cholera toxin stimulates IL-1 production and enhances antigen presentation by macrophages in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(9):2908-14.
-
1991: Czerkinsky C; Svennerholm A M; Quiding M; Jonsson R; Holmgren J
Antibody-producing cells in peripheral blood and salivary glands after oral cholera vaccination of humans.
Infection and immunity 1991;59(3):996-1001.
-
1990: Sanchez J; Johansson S; Löwenadler B; Svennerholm A M; Holmgren J
Recombinant cholera toxin B subunit and gene fusion proteins for oral vaccination.
Research in microbiology 1990;141(7-8):971-9.
-
1990: Dubey R S; Lindblad M; Holmgren J
Purification of El Tor cholera enterotoxins and comparisons with classical toxin.
Journal of general microbiology 1990;136(9):1839-47.
-
1990: Svennerholm A M; Wennerås C; Holmgren J; McConnell M M; Rowe B
Roles of different coli surface antigens of colonization factor antigen II in colonization by and protective immunogenicity of enterotoxigenic Escherichia coli in rabbits.
Infection and immunity 1990;58(2):341-6.
-
1990: Wennerås C; Holmgren J; Svennerholm A M
The binding of colonization factor antigens of enterotoxigenic Escherichia coli to intestinal cell membrane proteins.
FEMS microbiology letters 1990;54(1-3):107-12.
-
1990: Holmgren J; Svennerholm A M
New vaccines against bacterial enteric infections.
Scandinavian journal of infectious diseases. Supplementum 1990;70():149-56.
-
1990: Holmgren J; Svennerholm A M
Development of oral vaccines against cholera and enterotoxinogenic Escherichia coli diarrhea.
Scandinavian journal of infectious diseases. Supplementum 1990;76():47-53.
-
1989: Holmgren J; Fryklund J; Larsson H
Gamma-interferon-mediated down-regulation of electrolyte secretion by intestinal epithelial cells: a local immune mechanism?
Scandinavian journal of immunology 1989;30(4):499-503.
-
1989: Jonson G; Svennerholm A M; Holmgren J
Vibrio cholerae expresses cell surface antigens during intestinal infection which are not expressed during in vitro culture.
Infection and immunity 1989;57(6):1809-15.
-
1989: Svennerholm A M; Holmgren J; Sack D A
Development of oral vaccines against enterotoxinogenic Escherichia coli diarrhoea.
Vaccine 1989;7(3):196-8.
-
1989: Czerkinsky C; Russell M W; Lycke N; Lindblad M; Holmgren J
Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues.
Infection and immunity 1989;57(4):1072-7.
-
1989: Lycke N; Holmgren J
Adoptive transfer of gut mucosal antitoxin memory by isolated B cells 1 year after oral immunization with cholera toxin.
Infection and immunity 1989;57(4):1137-41.
-
1989: Holmgren J; Clemens J; Sack D A; Svennerholm A M
New cholera vaccines.
Vaccine 1989;7(2):94-6.
-
1989: Brezicka F T; Olling S; Nilsson O; Bergh J; Holmgren J; Sörenson S; Yngvason F; Lindholm L
Immunohistological detection of fucosyl-GM1 ganglioside in human lung cancer and normal tissues with monoclonal antibodies.
Cancer research 1989;49(5):1300-5.
-
1989: Glass R I; Svennerholm A M; Stoll B J; Khan M R; Huda S; Huq M I; Holmgren J
Effects of undernutrition on infection with Vibrio cholerae O1 and on response to oral cholera vaccine.
The Pediatric infectious disease journal 1989;8(2):105-9.
-
1989: Lycke N; Bromander A K; Ekman L; Karlsson U; Holmgren J
Cellular basis of immunomodulation by cholera toxin in vitro with possible association to the adjuvant function in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(1):20-7.
-
1989: Sanchez J; Holmgren J
Recombinant system for overexpression of cholera toxin B subunit in Vibrio cholerae as a basis for vaccine development.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(2):481-5.
-
1989: Lycke N; Bromander A K; Holmgren J
Role of local IgA antitoxin-producing cells for intestinal protection against cholera toxin challenge.
International archives of allergy and applied immunology 1989;88(3):273-9.
-
1988: Larson L N; Johansson C; Lindholm L; Holmgren J
Mouse monoclonal antibodies for experimental immunotherapy promotes killing of tumor cells.
International journal of cancer. Journal international du cancer 1988;42(6):877-82.
-
1988: Sanchez J; Svennerholm A M; Holmgren J
Genetic fusion of a non-toxic heat-stable enterotoxin-related decapeptide antigen to cholera toxin B-subunit.
FEBS letters 1988;241(1-2):110-4.
-
1988: Greenough W B; Glass R I; Holmgren J; Khan M R; Hossain K M; Huq I
Receptor blocking, cholera, and Escherichia coli toxins.
The Journal of infectious diseases 1988;158(5):1147-8.
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1988: Jertborn M; Svennerholm A M; Holmgren J
Five-year immunologic memory in Swedish volunteers after oral cholera vaccination.
The Journal of infectious diseases 1988;157(2):374-7.
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1988: Svennerholm A M; Vidal Y L; Holmgren J; McConnell M M; Rowe B
Role of PCF8775 antigen and its coli surface subcomponents for colonization, disease, and protective immunogenicity of enterotoxigenic Escherichia coli in rabbits.
Infection and immunity 1988;56(2):523-8.
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1988: Persson B E; Ståhle E; Påhlman L; Glimelius B; Holmgren J
CA-50 as a tumour marker for monitoring colorectal cancer: antigen rises in patients postoperatively precede clinical manifestations of recurrence.
European journal of cancer & clinical oncology 1988;24(2):241-6.
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1988: Holmgren J; Svennerholm A M; Gothefors L; Jertborn M; Stoll B
Enterotoxigenic Escherichia coli diarrhea in an endemic area prepares the intestine for an anamnestic immunoglobulin A antitoxin response to oral cholera B subunit vaccination.
Infection and immunity 1988;56(1):230-3.
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1988: Jertborn M; Svennerholm A M; Holmgren J
IgG and IgA subclass distribution of antitoxin antibody responses after oral cholera vaccination or cholera disease.
International archives of allergy and applied immunology 1988;85(3):358-63.
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1988: Lycke N; Holmgren J
Mucosal immune response to cholera toxin--cellular basis of memory and adjuvant action.
Monographs in allergy 1988;24():274-81.
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1988: Persson B E; Ståhle E; Påhlman L; Glimelius B; Nilsson O; Lindholm L; Norrgård-Pedersen B; Holmgren J
A clinical study of CA-50 as a tumour marker for monitoring of colorectal cancer.
Medical oncology and tumor pharmacotherapy 1988;5(3):165-71.
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1987: Holmgren J; Svennerholm A M; Clemens J; Sack D; Black R; Levine M
An oral B subunit-whole cell vaccine against cholera: from concept to successful field trial.
Advances in experimental medicine and biology 1987;216B():1649-60.
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1986: Lycke N; Svennerholm A M; Holmgren J
Strong biotype and serotype cross-protective antibacterial and antitoxic immunity in rabbits after cholera infection.
Microbial pathogenesis 1986;1(4):361-71.
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1986: Clemens J D; Jertborn M; Sack D; Stanton B; Holmgren J; Khan M R; Huda S
Effect of neutralization of gastric acid on immune responses to an oral B subunit, killed whole-cell cholera vaccine.
The Journal of infectious diseases 1986;154(1):175-8.
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1986: Stoll B J; Svennerholm A M; Gothefors L; Barua D; Huda S; Holmgren J
Local and systemic antibody responses to naturally acquired enterotoxigenic Escherichia coli diarrhea in an endemic area.
The Journal of infectious diseases 1986;153(3):527-34.
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1986: Nilsson O; Brezicka F T; Holmgren J; Sörenson S; Svennerholm L; Yngvason F; Lindholm L
Detection of a ganglioside antigen associated with small cell lung carcinomas using monoclonal antibodies directed against fucosyl-GM1.
Cancer research 1986;46(3):1403-7.
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1985: Glass R I; Holmgren J; Haley C E; Khan M R; Svennerholm A M; Stoll B J; Belayet Hossain K M; Black R E; Yunus M; Barua D
Predisposition for cholera of individuals with O blood group. Possible evolutionary significance.
American journal of epidemiology 1985;121(6):791-6.
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1985: Glass R I; Svennerholm A M; Khan M R; Huda S; Huq M I; Holmgren J
Seroepidemiological studies of El Tor cholera in Bangladesh: association of serum antibody levels with protection.
The Journal of infectious diseases 1985;151(2):236-42.
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1984: Svennerholm A M; Jertborn M; Gothefors L; Karim A M; Sack D A; Holmgren J
Mucosal antitoxic and antibacterial immunity after cholera disease and after immunization with a combined B subunit-whole cell vaccine.
The Journal of infectious diseases 1984;149(6):884-93.
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1984: Glass R I; Holmgren J; Khan M R; Hossain K M; Huq M I; Greenough W B
A randomized, controlled trial of the toxin-blocking effects of B subunit in family members of patients with cholera.
The Journal of infectious diseases 1984;149(4):495-500.
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1983: Glass R I; Svennerholm A M; Stoll B J; Khan M R; Hossain K M; Huq M I; Holmgren J
Protection against cholera in breast-fed children by antibodies in breast milk.
The New England journal of medicine 1983;308(23):1389-92.
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1983: Lindholm L; Holmgren J; Wikström M; Karlsson U; Andersson K; Lycke N
Monoclonal antibodies to cholera toxin with special reference to cross-reactions with Escherichia coli heat-labile enterotoxin.
Infection and immunity 1983;40(2):570-6.
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1983: Svennerholm A M; Jertborn M; Gothefors L; Karim A; Sack D A; Holmgren J
Current status of an oral B subunit whole cell cholera vaccine.
Developments in biological standardization 1983;53():73-9.
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1981: Greenough W B; Stoll B J; Holmgren J; Svennerholm L; Fredman P; Bardhan P K; Huq I
Toxin absorption in cholera.
Lancet 1981;2(8239):208.
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1980: Stoll B J; Holmgren J; Bardhan P K; Huq I; Greenough W B; Fredman P; Svennerholm L
Binding of intraluminal toxin in cholera: trial of GM1 ganglioside charcoal.
Lancet 1980;2(8200):888-91.
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