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Holm Holmsen

Research Profile

Anatomy

Blood Platelets

Chemicals & Drugs

Physiology

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TOP 3
Beata Olas; Holm Holmsen
Interaction of resveratrol with membrane glycerophospholipids in model system in vitro.
Anne Baumann; Anja Underhaug Gjerde; Wilhelm R Glomm; Holm Holmsen; Aurora Martinez; Catharina Svanborg; Ming Ying; Oyvind Halskau
HAMLET forms annular oligomers when deposited with phospholipid monolayers.
Hilde Dahl Haaland; Holm Holmsen
Potentiation by adrenaline of agonist-induced responses in normal human platelets in vitro.

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All Publications

2012: Beata Olas; Holm Holmsen
Interaction of resveratrol with membrane glycerophospholipids in model system in vitro.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(11):4028-34.
2012: Anne Baumann; Anja Underhaug Gjerde; Wilhelm R Glomm; Holm Holmsen; Aurora Martinez; Catharina Svanborg; Ming Ying; Oyvind Halskau
HAMLET forms annular oligomers when deposited with phospholipid monolayers.
Journal of molecular biology 2012;418(1-2):90-102.
2011: Hilde Dahl Haaland; Holm Holmsen
Potentiation by adrenaline of agonist-induced responses in normal human platelets in vitro.
Platelets 2011;22(5):328-37.
2011: Baard Olav Jensen; Rune Kleppe; Reidun Kopperud; Gyrid Nygaard; Stein Ove Døskeland; Holm Holmsen; Frode Selheim
Dipyridamole synergizes with nitric oxide to prolong inhibition of thrombin-induced platelet shape change.
Platelets 2011;22(1):8-19.
2010: Signe Steinkopf; Aida Simeunović; Helene J Bustad; Thi Ha Ngo; Hege Sveaass; Anja U Gjerde; Holm Holmsen
pH-dependent interaction of psychotropic drug with glycerophospholipid monolayers studied by the Langmuir technique.
Biophysical chemistry 2010;152(1-3):65-73.
2010: Ramadhan Oruch; Anders Lund; Ian F Pryme; Holm Holmsen
An intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes?
Journal of chemical biology 2010;3(2):67-88.
2009: Ramadhan Oruch; Erlend Hodneland; Ian F Pryme; Holm Holmsen
In thrombin stimulated human platelets Citalopram, Promethazine, Risperidone, and Ziprasidone, but not Diazepam, may exert their pharmacological effects also through intercalation in membrane phospholipids in a receptor-independent manner.
Journal of chemical biology 2009;2(2):89-103.
2009: Delphine Dutheil; Anja Underhaug Gjerde; Isabelle Petit-Paris; Gérard Mauco; Holm Holmsen
Polyethylene glycols interact with membrane glycerophospholipids: is this part of their mechanism for hypothermic graft protection?
Journal of chemical biology 2009;2(1):39-49.
2008: M Vorland; Vidar A T Thorsen; Holm Holmsen
Phospholipase D in platelets and other cells.
Platelets 2008;19(8):582-94.
2008: Ramadhan Oruch; Ian F Pryme; Holm Holmsen
Effects of psychotropic drugs on the thrombin-induced liberation of arachidonate in human platelets.
Saudi medical journal 2008;29(10):1397-407.
2008: Ramadhan Oruch; Erlend Hodneland; Ian F Pryme; Holm Holmsen
Psychotropic drugs interfere with the tight coupling of polyphosphoinositide cycle metabolites in human platelets: a result of receptor-independent drug intercalation in the plasma membrane?
Biochimica et biophysica acta 2008;1778(10):2165-76.
2008: M Vorland; Holm Holmsen
Phospholipase D activity in human platelets is inhibited by protein kinase A, involving inhibition of phospholipase D1 translocation.
Platelets 2008;19(4):300-7.
2008: M Vorland; Holm Holmsen
Phospholipase D in human platelets: presence of isoenzymes and participation of autocrine stimulation during thrombin activation.
Platelets 2008;19(3):211-24.
2008: Signe Steinkopf; Anja Katrin Schelderup; Hanne Linn Gjerde; Jeanette Pfeiffer; Synnøve Thoresen; Anja Underhaug Gjerde; Holm Holmsen
The psychotropic drug olanzapine (Zyprexa) increases the area of acid glycerophospholipid monolayers.
Biophysical chemistry 2008;134(1-2):39-46.
2007: Sonnich Meier; Thorny Cesilie Andersen; Kristin Lind-Larsen; Asbjørn Svardal; Holm Holmsen
Effects of alkylphenols on glycerophospholipids and cholesterol in liver and brain from female Atlantic cod (Gadus morhua).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2007;145(3):420-30.
2007: Agnieszka Broniec; Anja Underhaug Gjerde; Anne Berit Ølmheim; Holm Holmsen
Trifluoperazine causes a disturbance in glycerophospholipid monolayers containing phosphatidylserine (PS): effects of pH, acyl unsaturation, and proportion of PS.
Langmuir : the ACS journal of surfaces and colloids 2007;23(2):694-9.
2006: Anne M Bakken; Alexander Staeffler; Hugo A Jørgensen; Holm Holmsen
Glycerophospholipid molecular species in platelets and brain tissues - are platelets a good model for neurons?
Platelets 2006;17(7):484-92.
2006: Chen Song; Holm Holmsen; Willy Nerdal
Existence of lipid microdomains in bilayer of dipalmitoyl phosphatidylcholine (DPPC) and 1-stearoyl-2-docosahexenoyl phosphatidylserine (SDPS) and their perturbation by chlorpromazine: a 13C and 31P solid-state NMR study.
Biophysical chemistry 2006;120(3):178-87.
2006: Anna Blois; Holm Holmsen; Guglielmo Martino; Angelo Corti; Marie-Hélène Metz-Boutigue; Karen B Helle
Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine.
Regulatory peptides 2006;134(1):30-7.
2006: Eirik Søfteland; Tore Framstad; Astrid Nordvik; Anne M Bakken; Chandru Punwani; Inge Morild; Tor Hervig; Terje Thorsen; Holm Holmsen
Evaluation of a porcine model to study in vivo platelet activation.
Thrombosis research 2006;118(3):341-52.
2005: Ingunn Rødland; Øyvind Halskau; Aurora Martínez; Holm Holmsen
alpha-Lactalbumin binding and membrane integrity--effect of charge and degree of unsaturation of glycerophospholipids.
Biochimica et biophysica acta 2005;1717(1):11-20.
2005: Demetris Bitsanis; Michael A Crawford; Therishnee Moodley; Holm Holmsen; Kebreab Ghebremeskel; Ovrang Djahanbakhch
Arachidonic acid predominates in the membrane phosphoglycerides of the early and term human placenta.
The Journal of nutrition 2005;135(11):2566-71.
2005: Song Chen; Anja Underhaug Gjerde; Holm Holmsen; Willy Nerdal
Importance of polyunsaturated acyl chains in chlorpromazine interaction with phosphatidylserines: a 13C and 31P solid-state NMR study.
Biophysical chemistry 2005;117(2):101-9.
2005: Maria B Sandberg; Jakob Fridriksson; Lise Madsen; Vikas Rishi; Charles Vinson; Holm Holmsen; Rolf K Berge; Susanne Mandrup
Glucose-induced lipogenesis in pancreatic beta-cells is dependent on SREBP-1.
Molecular and cellular endocrinology 2005;240(1-2):94-106.
2005: Beata Olas; Barbara Wachowicz; Holm Holmsen; Miriam H Fukami
Resveratrol inhibits polyphosphoinositide metabolism in activated platelets.
Biochimica et biophysica acta 2005;1714(2):125-33.
2004: Baard Olav Jensen; Frode Selheim; Stein Ove Døskeland; Adrian R L Gear; Holm Holmsen
Protein kinase A mediates inhibition of the thrombin-induced platelet shape change by nitric oxide.
Blood 2004;104(9):2775-82.
2004: Anja Underhaug Gjerde; Holm Holmsen; Willy Nerdal
Chlorpromazine interaction with phosphatidylserines: a (13)C and (31)P solid-state NMR study.
Biochimica et biophysica acta 2004;1682(1-3):28-37.
2003: Knut S Andersen; Else L Nygreen; Ketil Grong; Beryl Leirvaag; Holm Holmsen
Comparison of the centrifugal and roller pump in elective coronary artery bypass surgery--a prospective, randomized study with special emphasis upon platelet activation.
Scandinavian cardiovascular journal : SCJ 2003;37(6):356-62.
2003: Henning Lygre; Grete Moe; Holm Holmsen
Interaction of ibuprofen with eukaryotic membrane lipids.
Acta odontologica Scandinavica 2003;61(5):303-9.
2003: Silje Skrede; Holm Holmsen
[A role for antipsychotic agents in the membrane hypothesis of schizophrenia?].
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række 2003;123(18):2568-70.
2003: Armelle Varnier Agasøster; Øyvind Halskau; Edvin Fuglebakk; Nils Age Frøystein; Arturo Muga; Holm Holmsen; Aurora Martínez
The interaction of peripheral proteins and membranes studied with alpha-lactalbumin and phospholipid bilayers of various compositions.
The Journal of biological chemistry 2003;278(24):21790-7.
2003: Vidar A T Thorsen; Marta Vorland; Bodil Bjørndal; Ove Bruland; Holm Holmsen; Johan R Lillehaug
Participation of phospholipase D and alpha/beta-protein kinase C in growth factor-induced signalling in C3H10T1/2 fibroblasts.
Biochimica et biophysica acta 2003;1632(1-3):62-71.
2003: Henning Lygre; Grete Moe; Rita Skålevik; Holm Holmsen
Interaction of triclosan with eukaryotic membrane lipids.
European journal of oral sciences 2003;111(3):216-22.
2002: Anneli Bohne; Miriam H Fukami; Holm Holmsen
EDTA inhibits collagen-induced ATP+ADP secretion and tyrosine phosphorylation in platelets independently of Mg2+ chelation and decrease in pH.
Platelets 2002;13(8):437-42.
2002: Beata Olas; Kerstin Lundell; Holm Holmsen; Miriam H Fukami
Biochemical properties of platelet microparticle membranes formed during exocytosis resemble organelles more than plasma membrane.
FEBS letters 2002;525(1-3):29-32.
2002: Hege Iversen; Edvin Fuglebakk; Holm Holmsen; Miriam H Fukami
Identification of minor metabolites of phospholipid signal molecules in [(32)P]P(i)-labelled platelets.
Platelets 2002;13(5-6):279-84.
2002: Frode Selheim; Holm Holmsen; Flemming S Vassbotn
Identification of functional VEGF receptors on human platelets.
FEBS letters 2002;512(1-3):107-10.
2002: Yoseph Tsegaye; Knut Olav Daasvatn; Holm Holmsen
Acyl specificity of phospholipases A2 and C in thrombin-stimulated human platelets.
Platelets 2002;13(1):31-5.
2001: Henning Lygre; M Vorland; Holm Holmsen
Interaction of a dental filling material eluate and membrane lipids.
Clinical oral investigations 2001;5(3):167-71.
2001: A Varnier Agasøster; Holm Holmsen
Chlorpromazine associates with phosphatidylserines to cause an increase in the lipid's own interfacial molecular area--role of the fatty acyl composition.
Biophysical chemistry 2001;91(1):37-47.
2001: A V Agasøsler; L M Tungodden; D Cejka; E Bakstad; L K Sydnes; Holm Holmsen
Chlorpromazine-induced increase in dipalmitoylphosphatidylserine surface area in monolayers at room temperature.
Biochemical pharmacology 2001;61(7):817-25.
2001: Michael A Crawford; M Bloom; Stephen C Cunnane; Holm Holmsen; Kebreab Ghebremeskel; John E Parkington; W Schmidt; A J Sinclair; C Leigh Broadhurst
Docosahexaenoic acid and cerebral evolution.
World review of nutrition and dietetics 2001;88():6-17.
2000: Frode Selheim; A K Frøyset; I Strand; Flemming S Vassbotn; Holm Holmsen
Adrenaline potentiates PI 3-kinase in platelets stimulated with thrombin and SFRLLN: role of secreted ADP.
FEBS letters 2000;485(1):62-6.
2000: P Tharmapathy; Miriam H Fukami; Holm Holmsen
The stimulatory effects of cationic amphiphilic drugs on human platelets treated with thrombin.
Biochemical pharmacology 2000;60(9):1267-77.
2000: P Tharmapathy; Frode Selheim; K Odegaard; A Lund; Holm Holmsen
Venlafaxine treatment stimulates blood platelet activity.
Journal of clinical psychopharmacology 2000;20(5):589-90.
2000: Vidar A T Thorsen; Bodil Bjørndal; G Nolan; Miriam H Fukami; Ove Bruland; Johan R Lillehaug; Holm Holmsen
Expression of a peptide binding to receptor for activated C-kinase (RACK1) inhibits phorbol myristoyl acetate-stimulated phospholipase D activity in C3H/10T1/2 cells: dissociation of phospholipase D-mediated phosphatidylcholine breakdown from its synthesis.
Biochimica et biophysica acta 2000;1487(2-3):163-76.
2000: Frode Selheim; Miriam H Fukami; Holm Holmsen; Flemming S Vassbotn
Platelet-derived-growth-factor-induced signalling in human platelets: phosphoinositide-3-kinase-dependent inhibition of platelet activation.
The Biochemical journal 2000;350 Pt 2():469-75.
2000: Willy Nerdal; S A Gundersen; Vidar A T Thorsen; H Høiland; Holm Holmsen
Chlorpromazine interaction with glycerophospholipid liposomes studied by magic angle spinning solid state (13)C-NMR and differential scanning calorimetry.
Biochimica et biophysica acta 2000;1464(1):165-75.
2000: J O Hindenes; Willy Nerdal; W Guo; L Di; D M Small; Holm Holmsen
Physical properties of the transmembrane signal molecule, sn-1-stearoyl 2-arachidonoylglycerol. Acyl chain segregation and its biochemical implications.
The Journal of biological chemistry 2000;275(10):6857-67.
2000: Frode Selheim; Holm Holmsen; Flemming S Vassbotn
PI 3-kinase signalling in platelets: the significance of synergistic, autocrine stimulation.
Platelets 2000;11(2):69-82.
1999: Frode Selheim; R Idsøe; Miriam H Fukami; Holm Holmsen; Flemming S Vassbotn
Formation of PI 3-kinase products in platelets by thrombin, but not collagen, is dependent on synergistic autocrine stimulation, particularly through secreted ADP.
Biochemical and biophysical research communications 1999;263(3):780-5.
1999: Frode Selheim; Holm Holmsen; Flemming S Vassbotn
Platelet-derived growth factor inhibits platelet activation in heparinized whole blood.
Thrombosis research 1999;95(4):185-96.
1999: K O Daasvatn; Holm Holmsen
Chlorpromazine and human platelet glycerolipid metabolism: precursor specificity and significance of drug-platelet interaction time.
Biochemical pharmacology 1999;57(10):1113-23.
1999: Anita Ryningen; Baard Olav Jensen; Holm Holmsen
Role of autocrine stimulation on the effects of cyclic AMP on protein and lipid phosphorylation in collagen-activated and thrombin-activated platelets.
European journal of biochemistry / FEBS 1999;260(1):87-96.
1998: Anita Ryningen; B Olav Jensen; Holm Holmsen
Elevation of cyclic AMP decreases phosphoinositide turnover and inhibits thrombin-induced secretion in human platelets.
Biochimica et biophysica acta 1998;1394(2-3):235-48.
1998: M Osman; H Høiland; Holm Holmsen; Y Ishigami
Tuning micelles of a bioactive heptapeptide biosurfactant via extrinsically induced conformational transition of surfactin assembly.
Journal of peptide science : an official publication of the European Peptide Society 1998;4(7):449-58.
1998: Anita Ryningen; Holm Holmsen
Role of autocrine stimulation for the effects of cyclic AMP on protein and lipid phosphorylation in platelets activated by particles.
FEBS letters 1998;436(3):335-8.
1998: Vidar A T Thorsen; Ove Bruland; Johan R Lillehaug; Holm Holmsen
Choline derived from the phosphatidylcholine specific phospholipase D is not directly available for the CDP choline pathway in phorbol ester-treated C3H10T1/2 Cl 8 fibroblasts.
Molecular and cellular biochemistry 1998;187(1-2):147-54.
1998: Anita Ryningen; Holm Holmsen
Thrombin per se does not induce tyrosine protein phosphorylation in human platelets as judged by western blotting, while collagen does: the significance of synergistic, autocrine stimulation.
Biochemical and biophysical research communications 1998;245(3):757-63.
1998: N Willumsen; H Vaagenes; Holm Holmsen; Rolf K Berge
On the effect of 2-deuterium- and 2-methyl-eicosapentaenoic acid derivatives on triglycerides, peroxisomal beta-oxidation and platelet aggregation in rats.
Biochimica et biophysica acta 1998;1369(2):193-203.
1997: Baard Olav Jensen; J Skeidsvoll; Holm Holmsen
A polarographic method for measuring dissolved nitric oxide.
Journal of biochemical and biophysical methods 1997;35(3):185-95.
1997: Charlotte Helleland; S A Eiane; Rolf K Berge; Holm Holmsen; Johan R Lillehaug
1-(Carboxymethylthio)tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10T1/2 cells.
Experimental cell research 1997;236(1):330-40.
1995: E Søfteland; T Hillestad; T Framstad; T Thorsen; Holm Holmsen
A transport and monitoring unit for piglets under general anaesthesia.
Laboratory animals 1995;29(3):282-5.
1995: E Søfteland; T Framstad; T Thorsen; Holm Holmsen
Evaluation of thiopentone-midazolam-fentanyl anaesthesia in pigs.
Laboratory animals 1995;29(3):269-75.
1995: E Søfteland; T Hervig; T Framstad; Holm Holmsen
Simple method for labeling of porcine platelets with indium-111 oxine.
Laboratory animal science 1995;45(2):195-8.
1995: M H Fukami; Holm Holmsen
Diacylglycerol elevations in control platelets are unaccompanied by pleckstrin phosphorylation. Implications for the role of diacylglycerol in platelet activation.
European journal of biochemistry / FEBS 1995;228(3):579-86.
1995: Anne M Bakken; Tor Hervig; Thor Thorsen; Holm Holmsen
Fatty acids in human platelets and plasma. Dietary seal oil decreases sensitivity toward microbubbles.
Platelets 1995;6(5):259-64.
1995: Baard Olav Jensen; Holm Holmsen
Nitric Oxide (NO)-Platelet Interactions: Inhibition is Independent of the Prostanoid and ADP Pathways.
Platelets 1995;6(2):83-90.
1994: E Søfteland; T Framstad; A Nordvik; I Strand; T Thorsen; Holm Holmsen
Nitrogen microbubbles induce a disappearance of single platelets (aggregation) with porcine platelets: a comparative study of the effects of anticoagulants and blood collection methods.
Thrombosis research 1994;76(1):61-70.
1994: Flemming S Vassbotn; O K Havnen; Carl-Henrik Heldin; Holm Holmsen
Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor.
The Journal of biological chemistry 1994;269(19):13874-9.
1994: Flemming S Vassbotn; Arne Ostman; Nina Langeland; Holm Holmsen; Bengt Westermark; Carl-Henrik Heldin; Monica Nistér
Activated platelet-derived growth factor autocrine pathway drives the transformed phenotype of a human glioblastoma cell line.
Journal of cellular physiology 1994;158(2):381-9.
1994: K R Kyvik; G M Aarbakke; H Klausen; Holm Holmsen; OB Tysnes
Hydrophobic organic solvents activate human platelets in vitro.
Platelets 1994;5(4):193-200.
1994: OB Tysnes; K R Kyvik; G M Aarbakke; Holm Holmsen
Organic Solvents Activate Human Platelets Through the Inositol Lipid-linked Signal Transduction System.
Platelets 1994;5(5):266-71.
1993: Vidar M Steen; Holm Holmsen; G Aarbakke
The platelet-stimulating effect of adrenaline through alpha 2-adrenergic receptors requires simultaneous activation by a true stimulatory platelet agonist. Evidence that adrenaline per se does not induce human platelet activation in vitro.
Thrombosis and haemostasis 1993;70(3):506-13.
1992: K W Frølich; G M Aarbakke; Holm Holmsen
Chlorpromazine increases the turnover of metabolically active phosphoinositides and elevates the steady-state level of phosphatidylinositol-4-phosphate in human platelets.
Biochemical pharmacology 1992;44(10):2013-20.
1992: E Søfteland; T Framstad; T Thorsen; Holm Holmsen
Porcine platelets in vitro and in vivo studies: relevance to human thrombosis research.
European journal of haematology 1992;49(4):161-73.
1992: Flemming S Vassbotn; R Skar; Holm Holmsen; Johan R Lillehaug
Absence of PDGF-induced, PKC-independent c-fos expression in a chemically transformed C3H/10T1/2 cell clone.
Experimental cell research 1992;202(1):98-104.
1992: Flemming S Vassbotn; Arne Ostman; Agneta Siegbahn; Holm Holmsen; Carl-Henrik Heldin
Neomycin is a platelet-derived growth factor (PDGF) antagonist that allows discrimination of PDGF alpha- and beta-receptor signals in cells expressing both receptor types.
The Journal of biological chemistry 1992;267(22):15635-41.
1992: Holm Holmsen; H Prydz
Portrait of a scientist.
Thrombosis research 1992;67(3):291-7.
1992: Holm Holmsen; J O Hindenes; M Fukami
Glycerophospholipid metabolism: back to the future.
Thrombosis research 1992;67(3):313-23.
1991: Holm Holmsen
Signal transducing mechanisms in platelets.
Proceedings of the National Science Council, Republic of China. Part B, Life sciences 1991;15(3):147-52.
1991: Anne M Bakken; M Farstad; Holm Holmsen
Fatty acids in human platelets and plasma. Fish oils decrease sensitivity toward N2 microbubbles.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;70(6):2669-72.
1991: Anne M Bakken; M Farstad; Holm Holmsen
Identity between palmitoyl-CoA synthetase and arachidonoyl-CoA synthetase in human platelet?
The Biochemical journal 1991;274 ( Pt 1)():145-52.
1991: OB Tysnes; Vidar M Steen; G M Aarbakke; Holm Holmsen
Stimulation of human platelets with low concentrations of thrombin: evidence for equimolar accumulation of inositol trisphosphates and phosphatidic acid.
The International journal of biochemistry 1991;23(3):305-10.
1990: Flemming S Vassbotn; Nina Langeland; I Hagen; Holm Holmsen
A monoclonal antibody against PDGF B-chain inhibits PDGF-induced DNA synthesis in C3H fibroblasts and prevents binding of PDGF to its receptor.
Biochimica et biophysica acta 1990;1054(2):246-9.
1990: Flemming S Vassbotn; Nina Langeland; Holm Holmsen
Neomycin inhibits PDGF-induced IP3 formation and DNA synthesis but not PDGF-stimulated uptake of inorganic phosphate in C3H/10T1/2 fibroblasts.
Biochimica et biophysica acta 1990;1054(2):207-12.
1990: Holm Holmsen; T Rygh
Chlorpromazine makes the platelet plasma membrane permeable for low-molecular weight substances and reduces ATP production.
Biochemical pharmacology 1990;40(2):373-6.
1990: OB Tysnes; Vidar M Steen; K W Frølich; Holm Holmsen
Evidence that chlorpromazine and prostaglandin E1 but not neomycin interfere with the inositol phospholipid metabolism in intact human platelets.
FEBS letters 1990;264(1):33-6.
1990: A J Verhoeven; J Marszalek; Holm Holmsen
Regulation of platelet AMP deaminase activity in situ.
The Biochemical journal 1990;265(1):267-75.
1989: Vidar M Steen; OB Tysnes; Holm Holmsen
Evidence for tight metabolic control of the receptor-activated polyphosphoinositide cycle in human platelets.
The Biochemical journal 1989;263(2):621-4.
1989: Nina Langeland; L J Moore; Holm Holmsen; Lars Haarr
Herpes simplex virus-1-specific proteins are involved in alteration of polyphosphoinositide metabolism in baby-hamster kidney cells.
The Biochemical journal 1989;261(2):683-6.
1989: Vidar M Steen; C A Cook; OB Tysnes; Holm Holmsen
Potentiation by adrenaline of thrombin-induced elevation of pHi is not essential for synergistic activation of human platelets.
FEBS letters 1989;250(2):211-4.
1989: Holm Holmsen; R Male; S Rongved; Nina Langeland; Johan R Lillehaug
Platelet-derived-growth-factor-stimulated heterogeneous polyphosphoinositide metabolism and phosphate uptake in C3H fibroblasts.
The Biochemical journal 1989;260(2):589-92.
1989: Holm Holmsen
Physiological functions of platelets.
Annals of medicine 1989;21(1):23-30.
1988: OB Tysnes; Vidar M Steen; Holm Holmsen
Neomycin inhibits platelet functions and inositol phospholipid metabolism upon stimulation with thrombin, but not with ionomycin or 12-O-tetradecanoyl-phorbol 13-acetate.
European journal of biochemistry / FEBS 1988;177(1):219-23.
1988: Vidar M Steen; OB Tysnes; Holm Holmsen
Synergism between thrombin and adrenaline (epinephrine) in human platelets. Marked potentiation of inositol phospholipid metabolism.
The Biochemical journal 1988;253(2):581-6.
1988: Nina Langeland; L J Moore; Holm Holmsen; Lars Haarr
Interaction of polylysine with the cellular receptor for herpes simplex virus type 1.
The Journal of general virology 1988;69 ( Pt 6)():1137-45.
1988: OB Tysnes; A J Verhoeven; Holm Holmsen
Rates of production and consumption of phosphatidic acid upon thrombin stimulation of human platelets.
European journal of biochemistry / FEBS 1988;174(1):75-9.
1987: Nina Langeland; Holm Holmsen; Johan R Lillehaug; Lars Haarr
Evidence that neomycin inhibits binding of herpes simplex virus type 1 to the cellular receptor.
Journal of virology 1987;61(11):3388-93.
1987: OB Tysnes; A J Verhoeven; Holm Holmsen
Studies on the preferential incorporation of [3H]glycerol over [32P]phosphate into major phospholipids of human platelets.
Biochimica et biophysica acta 1987;930(3):338-45.
1987: A J Verhoeven; OB Tysnes; G M Aarbakke; C A Cook; Holm Holmsen
Turnover of the phosphomonoester groups of polyphosphoinositol lipids in unstimulated human platelets.
European journal of biochemistry / FEBS 1987;166(1):3-9.
1987: OB Tysnes; A J Verhoeven; G M Aarbakke; Holm Holmsen
Phosphoinositide metabolism in resting and thrombin-stimulated human platelets. Evidence against metabolic heterogeneity.
FEBS letters 1987;218(1):68-72.
1987: A J Verhoeven; OB Tysnes; O Horvli; C A Cook; Holm Holmsen
Stimulation of phosphate uptake in human platelets by thrombin and collagen. Changes in specific 32P labeling of metabolic ATP and polyphosphoinositides.
The Journal of biological chemistry 1987;262(15):7047-52.
1987: Vidar M Steen; Holm Holmsen
Current aspects on human platelet activation and responses.
European journal of haematology 1987;38(5):383-99.
1986: Nina Langeland; Lars Haarr; Holm Holmsen
Evidence that neomycin inhibits HSV 1 infection of BHK cells.
Biochemical and biophysical research communications 1986;141(1):198-203.
1986: Nina Langeland; Lars Haarr; Holm Holmsen
Polyphosphoinositide metabolism in baby-hamster kidney cells infected with herpes simplex virus type 1.
The Biochemical journal 1986;237(3):707-12.
1985: OB Tysnes; G M Aarbakke; A J Verhoeven; Holm Holmsen
Thin-layer chromatography of polyphosphoinositides from platelet extracts: interference by an unknown phospholipid.
Thrombosis research 1985;40(3):329-38.