Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Jens Juul Holst

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Swine

Disorders

Type 2 Diabetes Mellitus

Anatomy

Procedures

Radioimmunoassay

Concepts & Ideas

Postprandial Period

Physiology

Gastric Emptying

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
38
Orskov, Cathrine
37
Poulsen, Steen Seier
32
Madsbad, Sten
28
Deacon, Carolyn
26
Rasmussen, TN
22
Nauck, Michael
14
Schmidt, Peter
14
Thulesen, Jesper
14
Hartmann, Bolette
12
Hellström, Per
12
Vilsbøll, Tina
11
Wettergren, André
11
Näslund, Erik
11
Schmiegel, Wolff
11
Krarup, Thure

Sign-in to see all Coauthors

Publications

TOP 3
Guldstrand M; Ahrén B; Näslund E; Holst J J; Adamson U
Dissociated incretin response to oral glucose at 1 year after restrictive vs. malabsorptive bariatric surgery.
Simonsen L; Pilgaard S; Carr R D; Kanstrup A B; Holst J J; Deacon C F
Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats.
Lerche Susanne; Soendergaard Liselotte; Rungby Joergen; Moeller Niels; Holst Jens Juul; Schmitz Ole E; Brock Birgitte
No increased risk of hypoglycaemic episodes during 48 h of subcutaneous glucagon-like-peptide-1 administration in fasting healthy subjects.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Jens Juul Holst (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Guldstrand M; Ahrén B; Näslund E; Holst J J; Adamson U
Dissociated incretin response to oral glucose at 1 year after restrictive vs. malabsorptive bariatric surgery.
Diabetes, obesity & metabolism 2009;11(11):1027-33.
2009: Simonsen L; Pilgaard S; Carr R D; Kanstrup A B; Holst J J; Deacon C F
Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2009;41(11):851-3.
2009: Lerche Susanne; Soendergaard Liselotte; Rungby Joergen; Moeller Niels; Holst Jens Juul; Schmitz Ole E; Brock Birgitte
No increased risk of hypoglycaemic episodes during 48 h of subcutaneous glucagon-like-peptide-1 administration in fasting healthy subjects.
Clinical endocrinology 2009;71(4):500-6.
2009: Faerch K; Borch-Johnsen K; Holst J J; Vaag A
Pathophysiology and aetiology of impaired fasting glycaemia and impaired glucose tolerance: does it matter for prevention and treatment of type 2 diabetes?
Diabetologia 2009;52(9):1714-23.
2009: Simonsen L; Pilgaard S; Orskov C; Hartmann B; Holst J J; Deacon C F
Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats.
Diabetes, obesity & metabolism 2009;11(9):884-90.
2009: Bucinskaite V; Tolessa T; Pedersen J; Rydqvist B; Zerihun L; Holst J J; Hellström P M
Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2009;21(9):978-e78.
2009: Sugiura K; Sonesson B; Akesson M; Björses K; Holst J; Malina M
The applicability of chimney grafts in the aortic arch.
The Journal of cardiovascular surgery 2009;50(4):475-81.
2009: Hansen K B; Knop F K; Holst J J; Vilsbøll T
Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists.
International journal of clinical practice 2009;63(8):1154-60.
2009: Ozer Esra Arun; Holst Jens Juul; Duman Nuray; Kumral Abdullah; Ozkan Hasan
The relationship between glucagon-like peptide 2 and feeding intolerance in preterm infants.
Journal of tropical pediatrics 2009;55(4):276-7.
2009: Holst Jens Juul; Seino Yutaka
GLP-1 receptor agonists: targeting both hyperglycaemia and disease processes in diabetes.
Diabetes research and clinical practice 2009;85(1):1-3.
2009: Bie-Olsen Lise G; Kjaer Troels W; Pedersen-Bjergaard Ulrik; Lonsdale Markus N; Holst Jens Juul; Law Ian; Thorsteinsson Birger
Changes of cognition and regional cerebral activity during acute hypoglycemia in normal subjects: A H2 15O positron emission tomographic study.
Journal of neuroscience research 2009;87(8):1922-8.
2009: Svendsen Pernille Fog; Nilas Lisbeth; Madsbad Sten; Holst Jens Juul
Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin.
Metabolism: clinical and experimental 2009;58(5):586-93.
2009: Zijlstra Nicolien; Mars Monica; de Wijk René A; Westerterp-Plantenga Margriet S; Holst Jens Juul; de Graaf Cees
Effect of viscosity on appetite and gastro-intestinal hormones.
Physiology & behavior 2009;97(1):68-75.
2009: Holst J; Resch T; Ivancev K; Björses K; Dias N; Lindblad B; Mathiessen S; Sonesson B; Malina M
Early and intermediate outcome of emergency endovascular aneurysm repair of ruptured infrarenal aortic aneurysm: a single-centre experience of 90 consecutive patients.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2009;37(4):413-9.
2009: Kalaitzakis Evangelos; Sadik Riadh; Holst Jens Juul; Ohman Lena; Björnsson Einar
Gut transit is associated with gastrointestinal symptoms and gut hormone profile in patients with cirrhosis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2009;7(3):346-52.
2009: Aaboe Kasper; Knop Filip Krag; Vilsboll Tina; Vølund Aage; Simonsen Ulf; Deacon Carolyn Fiona; Madsbad Sten; Holst Jens Juul; Krarup Thure
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2009;94(2):603-8.
2009: Højberg P V; Vilsbøll T; Rabøl R; Knop F K; Bache M; Krarup T; Holst J J; Madsbad S
Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes.
Diabetologia 2009;52(2):199-207.
2009: Jeppesen P B; Lund P; Gottschalck I B; Nielsen H B; Holst J J; Mortensen J; Poulsen S S; Quistorff B; Mortensen P B
Short bowel patients treated for two years with glucagon-like Peptide 2: effects on intestinal morphology and absorption, renal function, bone and body composition, and muscle function.
Gastroenterology research and practice 2009;2009():616054.
2009: Bremholm Lasse; Hornum Mads; Henriksen Birthe Merete; Larsen Steen; Holst Jens Juul
Glucagon-like peptide-2 increases mesenteric blood flow in humans.
Scandinavian journal of gastroenterology 2009;44(3):314-9.
2008: de Heer J; Rasmussen C; Coy D H; Holst J J
Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas.
Diabetologia 2008;51(12):2263-70.
2008: Højberg P V; Vilsbøll T; Zander M; Knop F K; Krarup T; Vølund A; Holst J J; Madsbad S
Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2008;25(11):1268-75.
2008: Aaboe Kasper; Krarup Thure; Madsbad Sten; Holst Jens Juul
GLP-1: physiological effects and potential therapeutic applications.
Diabetes, obesity & metabolism 2008;10(11):994-1003.
2008: Faerch K; Vaag A; Holst J J; Glümer C; Pedersen O; Borch-Johnsen K
Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action.
Diabetologia 2008;51(5):853-61.
2008: Højberg P V; Zander M; Vilsbøll T; Knop F K; Krarup T; Vølund A; Holst J J; Madsbad S
Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes.
Diabetologia 2008;51(4):632-40.
2008: Vestergaard Esben Thyssen; Djurhuus Christian Born; Gjedsted Jakob; Nielsen Søren; Møller Niels; Holst Jens Juul; Jørgensen Jens Otto Lunde; Schmitz Ole
Acute effects of ghrelin administration on glucose and lipid metabolism.
The Journal of clinical endocrinology and metabolism 2008;93(2):438-44.
2007: Korner Judith; Bessler Marc; Inabnet William; Taveras Carmen; Holst Jens Juul
Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2007;3(6):597-601.
2007: Holst Jens Juul
The physiology of glucagon-like peptide 1.
Physiological reviews 2007;87(4):1409-39.
2007: de Heer J; Pedersen J; Orskov C; Holst J J
The alpha cell expresses glucagon-like peptide-2 receptors and glucagon-like peptide-2 stimulates glucagon secretion from the rat pancreas.
Diabetologia 2007;50(10):2135-42.
2007: Hare Kristine Juul; Hartmann Bolette; Kissow Hannelouise; Holst Jens Juul; Poulsen Steen Seier
The intestinotrophic peptide, glp-2, counteracts intestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, gefitinib.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(17):5170-5.
2007: Sloth Birgitte; Davidsen Louise; Holst Jens Juul; Flint Anne; Astrup Arne
Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese males.
American journal of physiology. Endocrinology and metabolism 2007;293(2):E604-9.
2007: He Yan-Ling; Wang Yibin; Bullock Julie M; Deacon Carolyn F; Holst Jens Juul; Dunning Beth E; Ligueros-Saylan Monica; Foley James E
Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT.
Journal of clinical pharmacology 2007;47(5):633-41.
2007: Meier J J; Deacon C F; Schmidt W E; Holst J J; Nauck M A
Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjects.
Diabetologia 2007;50(4):806-13.
2007: Knop F K; Vilsbøll T; Madsbad S; Holst J J; Krarup T
Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus.
Diabetologia 2007;50(4):797-805.
2007: Sloth Birgitte; Holst Jens Juul; Flint Anne; Gregersen Nikolaj Ture; Astrup Arne
Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects.
American journal of physiology. Endocrinology and metabolism 2007;292(4):E1062-8.
2007: Lorenzen Janne Kunchel; Nielsen Sanne; Holst Jens Juul; Tetens Inge; Rehfeld Jens Frederik; Astrup Arne
Effect of dairy calcium or supplementary calcium intake on postprandial fat metabolism, appetite, and subsequent energy intake.
The American journal of clinical nutrition 2007;85(3):678-87.
2007: Ritzel R A; Kleine N; Holst J J; Willms B; Schmiegel W; Nauck M A
Preserved GLP-1 effects in a diabetic patient with Cushing's disease.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2007;115(2):146-50.
2007: Cypryk Katarzyna; Vilsbøll Tina; Nadel Iwona; Smyczynska Joanna; Holst Jens Juul; Lewinski Andrzej
Normal secretion of the incretin hormones glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 during gestational diabetes mellitus.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2007;23(1):58-62.
2007: Thorstenson Andreas; Jacobsson Hans; Onelöv Erik; Holst Jens Juul; Hellström Per M; Kinn Anne-Charlotte
Gastrointestinal function and metabolic control after construction of an orthotopic ileal neobladder in bladder cancer.
Scandinavian journal of urology and nephrology 2007;41(1):14-9.
2006: Vilsbøll Tina; Agersø Henrik; Lauritsen Torsten; Deacon Carolyn F; Aaboe Kasper; Madsbad Sten; Krarup Thure; Holst Jens Juul
The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.
Regulatory peptides 2006;137(3):168-72.
2006: Sørensen Heidi; Brand Christian L; Neschen Susanne; Holst Jens Juul; Fosgerau Keld; Nishimura Erica; Shulman Gerald I
Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice.
Diabetes 2006;55(10):2843-8.
2006: Levin F; Edholm T; Schmidt P T; Grybäck P; Jacobsson H; Degerblad M; Höybye C; Holst J J; Rehfeld J F; Hellström P M; Näslund E
Ghrelin stimulates gastric emptying and hunger in normal-weight humans.
The Journal of clinical endocrinology and metabolism 2006;91(9):3296-302.
2006: Nagell Carl Frederik; Wettergren André; Ørskov Cathrine; Holst Jens Juul
Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs.
Scandinavian journal of gastroenterology 2006;41(6):667-72.
2006: Haugaard S B; Andersen O; Pedersen S B; Dela F; Deacon C F; Holst J J; Iversen J; Madsbad S
Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagon, lactate and TNF-alpha in patients with HIV-lipodystrophy.
HIV medicine 2006;7(3):163-72.
2006: Simonsen L; Holst J J; Deacon C F
Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs.
Diabetologia 2006;49(4):706-12.
2006: Keller Jutta; Holst Jens Juul; Layer Peter
Inhibition of human pancreatic and biliary output but not intestinal motility by physiological intraileal lipid loads.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(4):G704-9.
2006: Meier J J; Gethmann A; Götze O; Gallwitz B; Holst J J; Schmidt W E; Nauck M A
Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans.
Diabetologia 2006;49(3):452-8.
2006: Holst J J
Glucagon-like peptide-1: from extract to agent. The Claude Bernard Lecture, 2005.
Diabetologia 2006;49(2):253-60.
2006: Zander M; Madsbad S; Deacon C F; Holst J J
The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes.
Diabetologia 2006;49(2):369-74.
2005: Kaushik Neeraj; Pietraszewski Marie; Holst Jens Juul; O'Keefe Stephen J D
Enteral feeding without pancreatic stimulation.
Pancreas 2005;31(4):353-9.
2005: Jensen Christine B; Storgaard Heidi; Holst Jens Juul; Dela Flemming; Madsbad Sten; Vaag Allan
Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls.
Metabolism: clinical and experimental 2005;54(10):1398-406.
2005: Jeppesen P B; Sanguinetti E L; Buchman A; Howard L; Scolapio J S; Ziegler T R; Gregory J; Tappenden K A; Holst J; Mortensen P B
Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients.
Gut 2005;54(9):1224-31.
2005: Plamboeck A; Holst J J; Carr R D; Deacon C F
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig.
Diabetologia 2005;48(9):1882-90.
2005: Meier J J; Gallwitz B; Askenas M; Vollmer K; Deacon C F; Holst J J; Schmidt W E; Nauck M A
Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes.
Diabetologia 2005;48(9):1872-81.
2005: Schmidt P T; Näslund E; Grybäck P; Jacobsson H; Holst J J; Hilsted L; Hellström P M
A role for pancreatic polypeptide in the regulation of gastric emptying and short-term metabolic control.
The Journal of clinical endocrinology and metabolism 2005;90(9):5241-6.
2005: Schou Jakob Hagen; Pilgaard Kasper; Vilsbøll Tina; Jensen Christine B; Deacon Carolyn F; Holst Jens Juul; Vølund Aage; Madsbad Sten; Vaag Allan A
Normal secretion and action of the gut incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in young men with low birth weight.
The Journal of clinical endocrinology and metabolism 2005;90(8):4912-9.
2005: Mari A; Sallas W M; He Y L; Watson C; Ligueros-Saylan M; Dunning B E; Deacon C F; Holst J J; Foley J E
Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2005;90(8):4888-94.
2005: Frid Anders H; Nilsson Mikael; Holst Jens Juul; Björck Inger M E
Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects.
The American journal of clinical nutrition 2005;82(1):69-75.
2005: Hermansen K; Hansen B; Jacobsen R; Clausen P; Dalgaard M; Dinesen B; Holst J J; Pedersen E; Astrup A
Effects of soy supplementation on blood lipids and arterial function in hypercholesterolaemic subjects.
European journal of clinical nutrition 2005;59(7):843-50.
2005: Larsen Philip J; Holst Jens Juul
Glucagon-related peptide 1 (GLP-1): hormone and neurotransmitter.
Regulatory peptides 2005;128(2):97-107.
2005: Miki Takashi; Minami Kohtaro; Shinozaki Hidehiro; Matsumura Kimio; Saraya Atsunori; Ikeda Hiroki; Yamada Yuichiro; Holst Jens Juul; Seino Susumu
Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility.
Diabetes 2005;54(4):1056-63.
2005: Hücking K; Kostic Z; Pox C; Ritzel R; Holst J J; Schmiegel W; Nauck M A
alpha-Glucosidase inhibition (acarbose) fails to enhance secretion of glucagon-like peptide 1 (7-36 amide) and to delay gastric emptying in Type 2 diabetic patients.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(4):470-6.
2005: Holst J J; Deacon C F
Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors.
Diabetologia 2005;48(4):612-5.
2005: Andersen O; Haugaard S B; Holst J J; Deacon C F; Iversen J; Andersen U B; Nielsen J O; Madsbad S
Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy.
HIV medicine 2005;6(2):91-8.
2005: Haugaard Steen B; Andersen Ove; Dela Flemming; Holst Jens Juul; Storgaard Heidi; Fenger Mogens; Iversen Johan; Madsbad Sten
Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells.
European journal of endocrinology / European Federation of Endocrine Societies 2005;152(1):103-12.
2005: Andreassen B U; Paerregaard A; Schmiegelow K; Rechnitzer C; Heilman C; Hartmann B; Holst J J; Michaelsen K F
Glucagon-like peptide-2 (GLP-2) response to enteral intake in children during anti-cancer treatment.
Journal of pediatric gastroenterology and nutrition 2005;40(1):48-53.
2005: Ørskov Cathrine; Hartmann Bolette; Poulsen Steen Seier; Thulesen Jesper; Hare Kristine Juul; Holst Jens Juul
GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors.
Regulatory peptides 2005;124(1-3):105-12.
2004: Holst Jens Juul; Orskov Cathrine
The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.
Diabetes 2004;53 Suppl 3():S197-204.
2004: Holst Jens Juul; Deacon Carolyn F
Glucagon-like peptide 1 and inhibitors of dipeptidyl peptidase IV in the treatment of type 2 diabetes mellitus.
Current opinion in pharmacology 2004;4(6):589-96.
2004: Nyström Thomas; Gutniak Mark K; Zhang Qimin; Zhang Fan; Holst Jens Juul; Ahrén Bo; Sjöholm Ake
Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease.
American journal of physiology. Endocrinology and metabolism 2004;287(6):E1209-15.
2004: Holst J J
On the physiology of GIP and GLP-1.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(11-12):747-54.
2004: Haugaard Steen B; Andersen Ove; Storgaard Heidi; Dela Flemming; Holst Jens Juul; Iversen Johan; Nielsen Jens Ole; Madsbad Sten
Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells.
American journal of physiology. Endocrinology and metabolism 2004;287(4):E677-85.
2004: Cayé-Thomasen Per; Schmidt Peter Thelin; Hermansson Ann; Holst Jens Juul; Thomsen Jens
Depletion of mucosal substance P in acute otitis media.
Acta oto-laryngologica 2004;124(7):794-7.
2004: Zander Mette; Christiansen Allan; Madsbad Sten; Holst Jens Juul
Additive effects of glucagon-like peptide 1 and pioglitazone in patients with type 2 diabetes.
Diabetes care 2004;27(8):1910-4.
2004: Holst Jens Juul; Gromada Jesper
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans.
American journal of physiology. Endocrinology and metabolism 2004;287(2):E199-206.
2004: Thulesen J; Hartmann B; Hare K J; Kissow H; Ørskov C; Holst J J; Poulsen S S
Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice.
Gut 2004;53(8):1145-50.
2004: Holst Jens Juul
Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.
Expert opinion on emerging drugs 2004;9(1):155-66.
2004: Nagell C F; Wettergren A; Pedersen J F; Mortensen D; Holst J J
Glucagon-like peptide-2 inhibits antral emptying in man, but is not as potent as glucagon-like peptide-1.
Scandinavian journal of gastroenterology 2004;39(4):353-8.
2004: Schmidt P T; Hansen L; Hilsted L; Holst J J
Cholecystokinin inhibits gastrin secretion independently of paracrine somatostatin secretion in the pig.
Scandinavian journal of gastroenterology 2004;39(3):217-21.
2004: Näslund Erik; King N; Mansten S; Adner N; Holst J J; Gutniak M; Hellström P M
Prandial subcutaneous injections of glucagon-like peptide-1 cause weight loss in obese human subjects.
The British journal of nutrition 2004;91(3):439-46.
2004: Henriksen Dennis B; Alexandersen Peter; Byrjalsen Inger; Hartmann Bolette; Bone Henry G; Christiansen Claus; Holst Jens Juul
Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2.
Bone 2004;34(1):140-7.
2004: Carstensen Marius; Thomsen Claus; Gotzsche Ole; Holst Jens Juul; Schrezenmeir Jürgen; Hermansen Kjeld
Differential postprandial lipoprotein responses in type 2 diabetic men with and without clinical evidence of a former myocardial infarction.
The review of diabetic studies : RDS 2004;1(4):175-84.
2003: Schmidt P T; Näslund E; Grybäck P; Jacobsson H; Hartmann B; Holst J J; Hellström P M
Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety.
Regulatory peptides 2003;116(1-3):21-5.
2003: Vilsbøll T; Knop F K; Krarup T; Johansen A; Madsbad S; Larsen S; Hansen T; Pedersen O; Holst J J
The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype.
The Journal of clinical endocrinology and metabolism 2003;88(10):4897-903.
2003: Zimmermann-Belsing Tina; Brabant Georg; Holst Jens Juul; Feldt-Rasmussen Ulla
Circulating leptin and thyroid dysfunction.
European journal of endocrinology / European Federation of Endocrine Societies 2003;149(4):257-71.
2003: Staehr P; Hojlund K; Hother-Nielsen O; Holst J J; Beck-Nielsen H
Does overnight normalization of plasma glucose by insulin infusion affect assessment of glucose metabolism in Type 2 diabetes?
Diabetic medicine : a journal of the British Diabetic Association 2003;20(10):816-22.
2003: Bakhøj S; Flint A; Holst J J; Tetens I
Lower glucose-dependent insulinotropic polypeptide (GIP) response but similar glucagon-like peptide 1 (GLP-1), glycaemic, and insulinaemic response to ancient wheat compared to modern wheat depends on processing.
European journal of clinical nutrition 2003;57(10):1254-61.
2003: Schmidt P T; Orskov C; Rasmussen T N; Holst J J
Nitric oxide has tonic inhibitory effect, but is not involved in the vagal control or VIP effects on motility of the porcine antrum.
Scandinavian journal of gastroenterology 2003;38(9):955-61.
2003: Meier S; Hücking K; Ritzel R; Holst J J; Schmiegel W H; Nauck M A
Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1 (GLP-1) in healthy volunteers.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2003;35(9):551-6.
2003: Møller Lars Neisig; Stidsen Carsten Enggaard; Hartmann Bolette; Holst Jens Juul
Somatostatin receptors.
Biochimica et biophysica acta 2003;1616(1):1-84.
2003: Mortensen Kristine; Christensen Louise Lundby; Holst Jens Juul; Orskov Cathrine
GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine.
Regulatory peptides 2003;114(2-3):189-96.
2003: Vilsbøll T; Krarup T; Sonne J; Madsbad S; Vølund A; Juul A G; Holst J J
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus.
The Journal of clinical endocrinology and metabolism 2003;88(6):2706-13.
2003: Meier J J; Gallwitz B; Siepmann N; Holst J J; Deacon C F; Schmidt W E; Nauck M A
Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia.
Diabetologia 2003;46(6):798-801.
2003: Piche Thierry; des Varannes Stanislas Bruley; Sacher-Huvelin Sylvie; Holst Jens Juul; Cuber Jean Claude; Galmiche Jean Paul
Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease.
Gastroenterology 2003;124(4):894-902.
2003: Sørensen L B; Flint A; Raben A; Hartmann B; Holst J J; Astrup A
No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2003;27(4):450-6.
2003: Gelling R W; Du X Q; Dichmann D S; Romer J; Huang H; Cui L; Obici S; Tang B; Holst J J; Fledelius C; Johansen P B; Rossetti L; Jelicks L A; Serup P; Nishimura E; Charron M J
Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1438-43.
2003: Staehr Peter; Hother-Nielsen Ole; Landau Bernard R; Chandramouli Visvanathan; Holst Jens Juul; Beck-Nielsen Henning
Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis.
Diabetes 2003;52(2):260-7.
2003: Vilsbøll T; Agersø H; Krarup T; Holst J J
Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects.
The Journal of clinical endocrinology and metabolism 2003;88(1):220-4.
2003: Nielsen T B; Yderstraede K B; Schrøder H D; Holst Jens Juul; Brusgaard Klaus; Beck-Nielsen H
Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters.
Cell transplantation 2003;12(1):13-25.
2003: Holst Jens Juul
Implementation of GLP-1 based therapy of type 2 diabetes mellitus using DPP-IV inhibitors.
Advances in experimental medicine and biology 2003;524():263-79.
2002: Cejvan Kenan; Coy David H; Holst Jens Juul; Cerasi Erol; Efendic Suad
Gliclazide directly inhibits arginine-induced glucagon release.
Diabetes 2002;51 Suppl 3():S381-4.
2002: Holst Jens Juul
Therapy of type 2 diabetes mellitus based on the actions of glucagon-like peptide-1.
Diabetes/metabolism research and reviews 2002;18(6):430-41.
2002: Ahrén B; Adner N; Svartberg J; Petrella E; Holst J J; Gutniak M K
Anti-diabetogenic effect of the human amylin analogue, pramlintide, in Type 1 diabetes is not mediated by GLP-1.
Diabetic medicine : a journal of the British Diabetic Association 2002;19(9):790-2.
2002: Vilsbøll T; Krarup T; Madsbad S; Holst J J
Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients.
Diabetologia 2002;45(8):1111-9.
2002: Bozkurt Ayhan; Näslund Erik; Holst Jens Juul; Hellström Per M
GLP-1 and GLP-2 act in concert to inhibit fasted, but not fed, small bowel motility in the rat.
Regulatory peptides 2002;107(1-3):129-35.
2002: Miyawaki Kazumasa; Yamada Yuichiro; Ban Nobuhiro; Ihara Yu; Tsukiyama Katsushi; Zhou Heying; Fujimoto Shimpei; Oku Akira; Tsuda Kinsuke; Toyokuni Shinya; Hiai Hiroshi; Mizunoya Wataru; Fushiki Tohru; Holst Jens Juul; Makino Mitsuhiro; Tashita Akira; Kobara Yukari; Tsubamoto Yoshiharu; Jinnouchi Takayoshi; Jomori Takahito; Seino Yutaka
Inhibition of gastric inhibitory polypeptide signaling prevents obesity.
Nature medicine 2002;8(7):738-42.
2002: Hannibal Jens; Fahrenkrug Jan; Holst Jens Juul
[A newly discovered photopigment in the retina, melanopsin, directs the biological clocks of the brain]
Ugeskrift for laeger 2002;164(19):2523.
2002: Hartmann Bolette; Thulesen Jesper; Hare Kristine Juul; Kissow Hannelouise; Orskov Cathrine; Poulsen Steen Seier; Holst Jens Juul
Immunoneutralization of endogenous glucagon-like peptide-2 reduces adaptive intestinal growth in diabetic rats.
Regulatory peptides 2002;105(3):173-9.
2002: Haderslev K V; Jeppesen P B; Hartmann B; Thulesen J; Sorensen H A; Graff J; Hansen B S; Tofteng F; Poulsen S S; Madsen J L; Holst J J; Staun M; Mortensen P B
Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon.
Scandinavian journal of gastroenterology 2002;37(4):392-8.
2002: Holst Jens Juul; Binderup Martin
[Fatty tissue and insulin resistance: resistin and adiponectin]
Ugeskrift for laeger 2002;164(16):2173-6.
2002: Jensen Christine B; Storgaard Heidi; Dela Flemming; Holst Jens Juul; Madsbad Sten; Vaag Allan A
Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight.
Diabetes 2002;51(4):1271-80.
2002: Hillingsø J G; Kjeldsen J; Schmidt P T; Rasmussen T N; Fisher-Hansen B; Holst J J; Lauristen K; Bukhave K; Rask-Madsen J
Effects of topical ropivacaine on eicosanoids and neurotransmitters in the rectum of patients with distal ulcerative colitis.
Scandinavian journal of gastroenterology 2002;37(3):325-9.
2002: Zander Mette; Madsbad Sten; Madsen Jan Lysgaard; Holst Jens Juul
Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study.
Lancet 2002;359(9309):824-30.
2002: Deacon C F; Wamberg S; Bie P; Hughes T E; Holst J J
Preservation of active incretin hormones by inhibition of dipeptidyl peptidase IV suppresses meal-induced incretin secretion in dogs.
The Journal of endocrinology 2002;172(2):355-62.
2002: Thulesen Jesper; Knudsen Lotte Bjerre; Hartmann Bolette; Hastrup Sven; Kissow Hannelouise; Jeppesen Palle Bekker; Ørskov Cathrine; Holst Jens Juul; Poulsen Steen Seier
The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist.
Regulatory peptides 2002;103(1):9-15.
2001: Meier J J; Hücking K; Holst J J; Deacon C F; Schmiegel W H; Nauck M A
Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes.
Diabetes 2001;50(11):2497-504.
2001: Verdich C; Flint A; Gutzwiller J P; Näslund E; Beglinger C; Hellström P M; Long S J; Morgan L M; Holst J J; Astrup A
A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans.
The Journal of clinical endocrinology and metabolism 2001;86(9):4382-9.
2001: Tornøe K; Hannibal J; Georg B; Schmidt P T; Hilsted L; Fahrenkrug J; Holst J J
PACAP 1-38 as neurotransmitter in the porcine antrum.
Regulatory peptides 2001;101(1-3):109-21.
2001: Rasmussen T N; Schmidt P; Poulsen S S; Holst J J
Effect of calcitonin gene-related peptide (CGRP) on motility and on the release of substance P, neurokinin A, somatostatin and gastrin in the isolated perfused porcine antrum.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2001;13(4):353-9.
2001: Toft-Nielsen M B; Madsbad S; Holst J J
Determinants of the effectiveness of glucagon-like peptide-1 in type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2001;86(8):3853-60.
2001: Toft-Nielsen M B; Damholt M B; Madsbad S; Hilsted L M; Hughes T E; Michelsen B K; Holst J J
Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients.
The Journal of clinical endocrinology and metabolism 2001;86(8):3717-23.
2001: Verdich C; Toubro S; Buemann B; Holst J J; Bülow J; Simonsen L; Søndergaard S B; Christensen N J; Astrup A
Leptin levels are associated with fat oxidation and dietary-induced weight loss in obesity.
Obesity research 2001;9(8):452-61.
2001: Rönnblom A; Hellström P M; Holst J J; Theodorsson E; Danielsson A
Gastric myoelectrical activity and gut hormone secretion in myotonic dystrophy.
European journal of gastroenterology & hepatology 2001;13(7):825-31.
2001: Zimmermann-Belsing T; Feldt-Rasmussen U; Holst J J
[Determination of free and bound leptin in serum: important during thyroid disease?]
Ugeskrift for laeger 2001;163(27):3808.
2001: Gutniak M K; Svartberg J; Hellström P M; Holst J J; Adner N; Ahrén B
Antidiabetogenic action of glucagon-like peptide-1 related to administration relative to meal intake in subjects with type 2 diabetes.
Journal of internal medicine 2001;250(1):81-7.
2001: Deacon C F; Danielsen P; Klarskov L; Olesen M; Holst J J
Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs.
Diabetes 2001;50(7):1588-97.
2001: Staehr P; Hother-Nielsen O; Levin K; Holst J J; Beck-Nielsen H
Assessment of hepatic insulin action in obese type 2 diabetic patients.
Diabetes 2001;50(6):1363-70.
2001: Friis-Hansen L; Lacourse K A; Samuelson L C; Holst J J
Attenuated processing of proglucagon and glucagon-like peptide-1 in carboxypeptidase E-deficient mice.
The Journal of endocrinology 2001;169(3):595-602.
2001: Holst J J
[Appetite regulation--leptin and other signal substances]
Ugeskrift for laeger 2001;163(21):2917-20.
2001: Zander M; Taskiran M; Toft-Nielsen M B; Madsbad S; Holst J J
Additive glucose-lowering effects of glucagon-like peptide-1 and metformin in type 2 diabetes.
Diabetes care 2001;24(4):720-5.
2001: Ritzel R; Schulte M; Pørksen N; Nauck M S; Holst J J; Juhl C; März W; Schmitz O; Schmiegel W H; Nauck M A
Glucagon-like peptide 1 increases secretory burst mass of pulsatile insulin secretion in patients with type 2 diabetes and impaired glucose tolerance.
Diabetes 2001;50(4):776-84.
2001: Rasmussen T N; Schmidt P; Poulsen S S; Holst J J
Localisation and neural control of the release of calcitonin gene-related peptide (CGRP) from the isolated perfused porcine ileum.
Regulatory peptides 2001;98(3):137-43.
2001: Vilsbøll T; Krarup T; Deacon C F; Madsbad S; Holst J J
Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.
Diabetes 2001;50(3):609-13.
2001: Jeppesen P B; Hartmann B; Thulesen J; Graff J; Lohmann J; Hansen B S; Tofteng F; Poulsen S S; Madsen J L; Holst J J; Mortensen P B
Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon.
Gastroenterology 2001;120(4):806-15.
2001: Thulesen J; Hartmann B; Kissow H; Jeppesen P B; Orskov C; Holst J J; Poulsen S S
Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal--jejunal transposition or small bowel resection.
Digestive diseases and sciences 2001;46(2):379-88.
2001: Näslund E; Bogefors J; Grybäck P; Bjellerup P; Jacobsson H; Holst J J; Hellström P M
GLP-1 inhibits gastric emptying of water but does not influence plasma.
Scandinavian journal of gastroenterology 2001;36(2):156-62.
2001: Vilsbøll T; Krarup T; Madsbad S; Holst J J
No reactive hypoglycaemia in Type 2 diabetic patients after subcutaneous administration of GLP-1 and intravenous glucose.
Diabetic medicine : a journal of the British Diabetic Association 2001;18(2):144-9.
2001: Hojlund K; Wildner-Christensen M; Eshøj O; Skjaerbaek C; Holst J J; Koldkjaer O; Møller Jensen D; Beck-Nielsen H
Reference intervals for glucose, beta-cell polypeptides, and counterregulatory factors during prolonged fasting.
American journal of physiology. Endocrinology and metabolism 2001;280(1):E50-8.
2001: Holst J J; Orskov C
Incretin hormones--an update.
Scandinavian journal of clinical and laboratory investigation. Supplementum 2001;234():75-85.
2000: Tornøe K; Hannibal J; Jensen T B; Georg B; Rickelt L F; Andreasen M B; Fahrenkrug J; Holst J J
PACAP-(1-38) as neurotransmitter in the porcine adrenal glands.
American journal of physiology. Endocrinology and metabolism 2000;279(6):E1413-25.
2000: Hartmann B; Thulesen J; Kissow H; Thulesen S; Orskov C; Ropke C; Poulsen S S; Holst J J
Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice.
Endocrinology 2000;141(11):4013-20.
2000: Thulesen J; Hartmann B; Orskov C; Jeppesen P B; Holst J J; Poulsen S S
Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2.
Peptides 2000;21(10):1511-7.
2000: Deacon C F; Nauck M A; Meier J; Hücking K; Holst J J
Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide.
The Journal of clinical endocrinology and metabolism 2000;85(10):3575-81.
2000: Holst J J
Gut hormones as pharmaceuticals. From enteroglucagon to GLP-1 and GLP-2.
Regulatory peptides 2000;93(1-3):45-51.
2000: Jeppesen P B; Hartmann B; Thulesen J; Hansen B S; Holst J J; Poulsen S S; Mortensen P B
Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon.
Gut 2000;47(3):370-6.
2000: Buemann B; Toubro S; Holst J J; Rehfeld J F; Bibby B M; Astrup A
D-tagatose, a stereoisomer of D-fructose, increases blood uric acid concentration.
Metabolism: clinical and experimental 2000;49(8):969-76.
2000: Hartmann B; Harr M B; Jeppesen P B; Wojdemann M; Deacon C F; Mortensen P B; Holst J J
In vivo and in vitro degradation of glucagon-like peptide-2 in humans.
The Journal of clinical endocrinology and metabolism 2000;85(8):2884-8.
2000: Verdich C; Madsen J L; Toubro S; Buemann B; Holst J J; Astrup A
Effect of obesity and major weight reduction on gastric emptying.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(7):899-905.
2000: Henriksen J E; Levin K; Thye-Rønn P; Alford F; Hother-Nielsen O; Holst J J; Beck-Nielsen H
Glucose-mediated glucose disposal in insulin-resistant normoglycemic relatives of type 2 diabetic patients.
Diabetes 2000;49(7):1209-18.
2000: Vilsbøll T; Toft-Nielsen M B; Krarup T; Madsbad S; Dinesen B; Holst J J
Evaluation of beta-cell secretory capacity using glucagon-like peptide 1.
Diabetes care 2000;23(6):807-12.
2000: Hansen L; Hartmann B; Bisgaard T; Mineo H; Jørgensen P N; Holst J J
Somatostatin restrains the secretion of glucagon-like peptide-1 and -2 from isolated perfused porcine ileum.
American journal of physiology. Endocrinology and metabolism 2000;278(6):E1010-8.
2000: Schmidt P T; Holst J J
Tachykinins in regulation of gastric motility and secretion.
Cellular and molecular life sciences : CMLS 2000;57(4):579-88.
2000: Schmidt P T; Tornøe K; Poulsen S S; Rasmussen T N; Holst J J
Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors.
Pancreas 2000;20(3):241-7.
2000: Hartmann B; Johnsen A H; Orskov C; Adelhorst K; Thim L; Holst J J
Structure, measurement, and secretion of human glucagon-like peptide-2.
Peptides 2000;21(1):73-80.
1999: Klausen B; Toubro S; Ranneries C; Rehfeld J F; Holst J J; Christensen N J; Astrup A
Increased intensity of a single exercise bout stimulates subsequent fat intake.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23(12):1282-7.
1999: Hansen L; Deacon C F; Orskov C; Holst J J
Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine.
Endocrinology 1999;140(11):5356-63.
1999: Holst J J
Glucagon-like peptide-1, a gastrointestinal hormone with a pharmaceutical potential.
Current medicinal chemistry 1999;6(11):1005-17.
1999: Schmidt P T; Eriksen L; Loftager M; Rasmussen T N; Holst J J
Fast acting nervous regulation of immunoglobulin A secretion from isolated perfused porcine ileum.
Gut 1999;45(5):679-85.
1999: Thulesen J; Hartmann B; Nielsen C; Holst J J; Poulsen S S
Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat: effects of dietary fibre.
Gut 1999;45(5):672-8.
1999: Damholt A B; Buchan A M; Holst J J; Kofod H
Proglucagon processing profile in canine L cells expressing endogenous prohormone convertase 1/3 and prohormone convertase 2.
Endocrinology 1999;140(10):4800-8.
1999: Jeppesen P B; Hartmann B; Hansen B S; Thulesen J; Holst J J; Mortensen P B
Impaired meal stimulated glucagon-like peptide 2 response in ileal resected short bowel patients with intestinal failure.
Gut 1999;45(4):559-63.
1999: Olesen M; Gudmand-Høyer E; Holst J J; Jørgensen S
Importance of colonic bacterial fermentation in short bowel patients: small intestinal malabsorption of easily digestible carbohydrate.
Digestive diseases and sciences 1999;44(9):1914-23.
1999: Näslund E; Bogefors J; Skogar S; Grybäck P; Jacobsson H; Holst J J; Hellström P M
GLP-1 slows solid gastric emptying and inhibits insulin, glucagon, and PYY release in humans.
The American journal of physiology 1999;277(3 Pt 2):R910-6.
1999: Schmidt P T; Rasmussen T N; Holst J J
Tachykinins stimulate acid and pepsinogen secretion in the isolated porcine stomach.
Acta physiologica Scandinavica 1999;166(4):335-40.
1999: Schmidt P T; Rickelt L F; Holst J J
Tachykinins stimulate release of peptide hormones (glucagon-like peptide-1) and paracrine (somatostatin) and neurotransmitter (vasoactive intestinal polypeptide) from porcine ileum through NK-1 receptors.
Digestive diseases and sciences 1999;44(7):1273-81.
1999: Wøjdemann M; Wettergren A; Hartmann B; Hilsted L; Holst J J
Inhibition of sham feeding-stimulated human gastric acid secretion by glucagon-like peptide-2.
The Journal of clinical endocrinology and metabolism 1999;84(7):2513-7.
1999: Toft-Nielsen M B; Madsbad S; Holst J J
Continuous subcutaneous infusion of glucagon-like peptide 1 lowers plasma glucose and reduces appetite in type 2 diabetic patients.
Diabetes care 1999;22(7):1137-43.
1999: Wøjdemann M; Riber C; Bisgaard T; Sternby B; Larsen S; Rehfeld J F; Holst J J; Olsen O
Inhibition of human gastric lipase by intraduodenal fat involves glucagon-like peptide-1 and cholecystokinin.
Regulatory peptides 1999;80(3):101-6.
1999: Näslund E; Barkeling B; King N; Gutniak M; Blundell J E; Holst J J; Rössner S; Hellström P M
Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1999;23(3):304-11.
1998: Holst J J; Deacon C; Toft-Nielsen M B; Bjerre-Knudsen L
On the treatment of diabetes mellitus with glucagon-like peptide-1.
Annals of the New York Academy of Sciences 1998;865():336-43.
1998: Zimmermann-Belsing T; Dreyer M; Holst J J; Feldt-Rasmussen U
The relationship between the serum leptin concentrations of thyrotoxic patients during treatment and their total fat mass is different from that of normal subjects.
Clinical endocrinology 1998;49(5):589-95.
1998: Nauck M A; Weber I; Bach I; Richter S; Orskov C; Holst J J; Schmiegel W
Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients.
Diabetic medicine : a journal of the British Diabetic Association 1998;15(11):937-45.
1998: Wettergren A; Wøjdemann M; Holst J J
Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow.
The American journal of physiology 1998;275(5 Pt 1):G984-92.
1998: Nauck M A; Sauerwald A; Ritzel R; Holst J J; Schmiegel W
Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure.
Diabetes care 1998;21(11):1925-31.
1998: Holst J J; Deacon C F
Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes.
Diabetes 1998;47(11):1663-70.
1998: Wettergren A; Pridal L; Wøjdemann M; Holst J J
Amidated and non-amidated glucagon-like peptide-1 (GLP-1): non-pancreatic effects (cephalic phase acid secretion) and stability in plasma in humans.
Regulatory peptides 1998;77(1-3):83-7.
1998: Toft-Nielsen M; Madsbad S; Holst J J
Exaggerated secretion of glucagon-like peptide-1 (GLP-1) could cause reactive hypoglycaemia.
Diabetologia 1998;41(10):1180-6.
1998: Wøjdemann M; Wettergren A; Hartmann B; Holst J J
Glucagon-like peptide-2 inhibits centrally induced antral motility in pigs.
Scandinavian journal of gastroenterology 1998;33(8):828-32.
1998: Näslund E; Backman L; Holst J J; Theodorsson E; Hellström P M
Importance of small bowel peptides for the improved glucose metabolism 20 years after jejunoileal bypass for obesity.
Obesity surgery 1998;8(3):253-60.
1998: Seifarth C; Bergmann J; Holst J J; Ritzel R; Schmiegel W; Nauck M A
Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to alpha-glucosidase inhibition (acarbose) in Type 2 diabetic patients.
Diabetic medicine : a journal of the British Diabetic Association 1998;15(6):485-91.
1998: Näslund E; Grybäck P; Backman L; Jacobsson H; Holst J J; Theodorsson E; Hellström P M
Distal small bowel hormones: correlation with fasting antroduodenal motility and gastric emptying.
Digestive diseases and sciences 1998;43(5):945-52.
1998: Deacon C F; Hughes T E; Holst J J
Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.
Diabetes 1998;47(5):764-9.
1998: Holst J J
[Glucagon-like peptide-1--a new hormone and a new drug]
Ugeskrift for laeger 1998;160(16):2371-7.
1998: Wøjdemann M; Wettergren A; Sternby B; Holst J J; Larsen S; Rehfeld J F; Olsen O
Inhibition of human gastric lipase secretion by glucagon-like peptide-1.
Digestive diseases and sciences 1998;43(4):799-805.
1998: Gromada J; Holst J J; Rorsman P
Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.
Pflügers Archiv : European journal of physiology 1998;435(5):583-94.
1998: Deacon C F; Knudsen L B; Madsen K; Wiberg F C; Jacobsen O; Holst J J
Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity.
Diabetologia 1998;41(3):271-8.
1998: Rasmussen T N; Bersani M; Schmidt P; Thim L; Kofod H; Jørgensen P N; Poulsen S S; Holst J J
Isolation and molecular characterization of porcine calcitonin gene-related peptide (CGRP) and its endocrine effects in the porcine pancreas.
Pancreas 1998;16(2):195-204.
1998: Holst J J
[Obesity--did anything happen since leptin?]
Ugeskrift for laeger 1998;160(8):1182-4.
1998: Svartberg J; Holst J J; Gutniak M; Adner N
The ethanol augmentation of glucose-induced insulin secretion is abolished by calcium antagonism with nifedipine: no evidence for a role of glucagon-like peptide-1 (GLP-1).
Pancreas 1998;16(1):66-71.
1998: Gromada J; Bokvist K; Ding W G; Holst J J; Nielsen J H; Rorsman P
Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling.
Diabetes 1998;47(1):57-65.
1998: Wettergren A; Wøjdemann M; Holst J J
The inhibitory effect of glucagon-like peptide-1 (7-36)amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36)amide.
Peptides 1998;19(5):877-82.
1998: Willms B; Idowu K; Holst J J; Creutzfeldt W; Nauck M A
Overnight GLP-1 normalizes fasting but not daytime plasma glucose levels in NIDDM patients.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1998;106(2):103-7.
1997: Rasmussen T N; Harling H; Rehfeld J F; Holst J J
Calcitonin gene-related peptide (CGRP), a potent regulator of biliary flow.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 1997;9(4):215-20.
1997: Holst J J
[Molecular biology of pain. Cloning of a temperature sensitive pain receptor]
Ugeskrift for laeger 1997;159(50):7507-8.
1997: Nauck M A; Niedereichholz U; Ettler R; Holst J J; Orskov C; Ritzel R; Schmiegel W H
Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans.
The American journal of physiology 1997;273(5 Pt 1):E981-8.
1997: Drewes C; Nauck M A; Horn R; Holst J; Schmiegel W; Brabant G
A liquid mixed meal or exogenous glucagon-like peptide 1 (GLP-1) do not alter plasma leptin concentrations in healthy volunteers.
Acta diabetologica 1997;34(3):230-4.
1997: Nauck M A; Holst J J; Willms B
Glucagon-like peptide 1 and its potential in the treatment of non-insulin-dependent diabetes mellitus.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1997;29(9):411-6.
1997: Rasmussen L; Qvist N; Oster-Jørgensen E; Rehfeld J F; Holst J J; Pedersen S A
A double-blind placebo-controlled study on the effects of omeprazole on gut hormone secretion and gastric emptying rate.
Scandinavian journal of gastroenterology 1997;32(9):900-5.
1997: Tornøe K; Hannibal J; Fahrenkrug J; Holst J J
PACAP-(1-38) as neurotransmitter in pig pancreas: receptor activation revealed by the antagonist PACAP-(6-38).
The American journal of physiology 1997;273(2 Pt 1):G436-46.
1997: Holst J J; Gromada J; Nauck M A
The pathogenesis of NIDDM involves a defective expression of the GIP receptor.
Diabetologia 1997;40(8):984-6.
1997: Wettergren A; Wøjdemann M; Meisner S; Stadil F; Holst J J
The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.
Gut 1997;40(5):597-601.
1997: Palnaes Hansen C; Andreasen J J; Holst J J
The release of gastric inhibitory peptide, glucagon-like peptide-I, and insulin after oral glucose test in colectomized subjects.
Scandinavian journal of gastroenterology 1997;32(5):473-7.
1997: Näslund E; Grybäck P; Hellström P M; Jacobsson H; Holst J J; Theodorsson E; Backman L
Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1997;21(5):387-92.
1997: Larsen P J; Tang-Christensen M; Holst J J; Orskov C
Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem.
Neuroscience 1997;77(1):257-70.
1997: Thulesen J; Orskov C; Holst J J; Poulsen S S
Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats.
Endocrinology 1997;138(1):62-8.
1997: Schmidt P T; Rasmussen T N; Holst J J
Tachykinins may mediate capsaicin-induced, but not vagally induced motility in porcine antrum.
Peptides 1997;18(10):1511-6.
1997: Nauck M A; Holst J J; Willms B; Schmiegel W
Glucagon-like peptide 1 (GLP-1) as a new therapeutic approach for type 2-diabetes.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1997;105(4):187-95.
1997: Schmidt P T; Holst J J
Use of antagonists to define tachykininergic control of intestinal motility in pigs.
Peptides 1997;18(3):373-9.
1997: Holst J J
Enteroglucagon.
Annual review of physiology 1997;59():257-71.
1996: Holst J J; Toft-Nielsen M B; Orskov C; Nauck M; Willms B
On the effects of glucagon-like peptide-1 on blood glucose regulation in normal and diabetic subjects.
Annals of the New York Academy of Sciences 1996;805():729-36.
1996: Tornøe K; Hannibal J; Giezemann M; Schmidt P; Holst J J
PACAP 1-27 and 1-38 in the porcine pancreas: occurrence, localization, and effects.
Annals of the New York Academy of Sciences 1996;805():521-35.
1996: Nauck M A; Wollschläger D; Werner J; Holst J J; Orskov C; Creutzfeldt W; Willms B
Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM.
Diabetologia 1996;39(12):1546-53.
1996: Holst J J
[Leptin--a new weight-loss agent?]
Nordisk medicin 1996;111(9):300-3.
1996: Christiansen E; Tibell A; Vølund A; Rasmussen K; Groth C G; Holst J J; Pedersen O; Christensen N J; Madsbad S
Pancreatic endocrine function in recipients of segmental and whole pancreas transplantation.
The Journal of clinical endocrinology and metabolism 1996;81(11):3972-9.
1996: Schmidt P; Poulsen S S; Hilsted L; Rasmussen T N; Holst J J
Tachykinins mediate vagal inhibition of gastrin secretion in pigs.
Gastroenterology 1996;111(4):925-35.
1996: Holst J J
GLP-1 in NIDDM.
Diabetic medicine : a journal of the British Diabetic Association 1996;13(9 Suppl 6):S156-60.
1996: Deacon C F; Pridal L; Klarskov L; Olesen M; Holst J J
Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in the anesthetized pig.
The American journal of physiology 1996;271(3 Pt 1):E458-64.
1996: Holst J J
[Leptin--a new way to diet?]
Ugeskrift for laeger 1996;158(32):4505-8.
1996: Brand C L; Jørgensen P N; Svendsen I; Holst J J
Evidence for a major role for glucagon in regulation of plasma glucose in conscious, nondiabetic, and alloxan-induced diabetic rabbits.
Diabetes 1996;45(8):1076-83.
1996: Holst J J
Glucagon, glucagon-like peptide-1 and their receptors: an introduction.
Acta physiologica Scandinavica 1996;157(3):309-15.
1996: Orskov C; Wettergren A; Holst J J
Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day.
Scandinavian journal of gastroenterology 1996;31(7):665-70.
1996: Toft-Nielsen M; Hvidberg A; Hilsted J; Dige-Petersen H; Holst J J
No effect of beta-adrenergic blockade on hypoglycaemic effect of glucagon-like peptide-1 (GLP-1) in normal subjects.
Diabetic medicine : a journal of the British Diabetic Association 1996;13(6):544-8.
1996: Orskov C; Poulsen S S; Møller M; Holst J J
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I.
Diabetes 1996;45(6):832-5.
1996: Toft-Nielson M; Madsbad S; Holst J J
The effect of glucagon-like peptide I (GLP-I) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones.
Diabetes 1996;45(5):552-6.
1996: Pridal L; Deacon C F; Kirk O; Christensen J V; Carr R D; Holst J J
Glucagon-like peptide-1(7-37) has a larger volume of distribution than glucagon-like peptide-1(7-36)amide in dogs and is degraded more quickly in vitro by dog plasma.
European journal of drug metabolism and pharmacokinetics 1996;21(1):51-9.
1996: Goll R; Nielsen S H; Holst J J
Regulation of motilin release from isolated perfused pig duodenum.
Digestion 1996;57(5):341-8.
1996: Holst J J; Fahrenkrug J; Stadil F; Rehfeld J F
Gastrointestinal endocrinology.
Scandinavian journal of gastroenterology. Supplement 1996;216():27-38.
1995: Deacon C F; Nauck M A; Toft-Nielsen M; Pridal L; Willms B; Holst J J
Both subcutaneously and intravenously administered glucagon-like peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects.
Diabetes 1995;44(9):1126-31.
1995: Brand C L; Jørgensen P N; Knigge U; Warberg J; Svendsen I; Kristensen J S; Holst J J
Role of glucagon in maintenance of euglycemia in fed and fasted rats.
The American journal of physiology 1995;269(3 Pt 1):E469-77.
1995: Deacon C F; Johnsen A H; Holst J J
Human colon produces fully processed glucagon-like peptide-1 (7-36) amide.
FEBS letters 1995;372(2-3):269-72.
1995: Pridal L; Ingwersen S H; Larsen F S; Holst J J; Adelhorst K; Kirk O
Comparison of sandwich enzyme-linked immunoadsorbent assay and radioimmunoassay for determination of exogenous glucagon-like peptide-1(7-36)amide in plasma.
Journal of pharmaceutical and biomedical analysis 1995;13(7):841-50.
1995: Ritzel R; Orskov C; Holst J J; Nauck M A
Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7-36 amide] after subcutaneous injection in healthy volunteers. Dose-response-relationships.
Diabetologia 1995;38(6):720-5.
1995: Deacon C F; Johnsen A H; Holst J J
Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo.
The Journal of clinical endocrinology and metabolism 1995;80(3):952-7.
1994: Holst J J
Glucagonlike peptide 1: a newly discovered gastrointestinal hormone.
Gastroenterology 1994;107(6):1848-55.
1994: Thulesen J; Rasmussen T N; Schmidt P; Holst J J; Poulsen S S
Calcitonin gene-related peptide (CGRP) in the nipple of the rat mammary gland.
Histochemistry 1994;102(6):437-44.
1994: Brand C L; Rolin B; Jørgensen P N; Svendsen I; Kristensen J S; Holst J J
Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycaemia in moderately streptozotocin-diabetic rats.
Diabetologia 1994;37(10):985-93.
1994: Holst J J; Bersani M; Johnsen A H; Kofod H; Hartmann B; Orskov C
Proglucagon processing in porcine and human pancreas.
The Journal of biological chemistry 1994;269(29):18827-33.
1994: Goll R; Poulsen J H; Schmidt P; Schjoldager B; Poulsen S S; Holst J J
Peptide-evoked release of amylase from isolated acini of the rat parotid gland.
Regulatory peptides 1994;51(3):237-54.
1994: Holst J J; Rasmussen T N; Schmidt P
Role of nitric oxide in neurally induced pancreatic exocrine secretion in pigs.
The American journal of physiology 1994;266(2 Pt 1):G206-13.
1994: Hvidberg A; Nielsen M T; Hilsted J; Orskov C; Holst J J
Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man.
Metabolism: clinical and experimental 1994;43(1):104-8.
1994: Holst J J; Schmidt P
Gut hormones and intestinal function.
Baillière's clinical endocrinology and metabolism 1994;8(1):137-64.
1994: Rasmussen T N; Bersani M; Johnsen A H; Kofod H; Holst J J
Pigs produce only a single form of CGRP, part of which is processed to N- and C-terminal fragments.
Peptides 1994;15(1):89-94.
1994: Andreasen J J; Orskov C; Holst J J
Secretion of glucagon-like peptide-1 and reactive hypoglycemia after partial gastrectomy.
Digestion 1994;55(4):221-8.
1993: Holst J J; Bersani M; Hvidberg A; Knigge U; Christiansen E; Madsbad S; Harling H; Kofod H
On the effects of human galanin in man.
Diabetologia 1993;36(7):653-7.
1993: Orskov C; Wettergren A; Holst J J
Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable.
Diabetes 1993;42(5):658-61.
1993: Wettergren A; Schjoldager B; Mortensen P E; Myhre J; Christiansen J; Holst J J
Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man.
Digestive diseases and sciences 1993;38(4):665-73.
1993: Lanng S; Thorsteinsson B; Røder M E; Orskov C; Holst J J; Nerup J; Koch C
Pancreas and gut hormone responses to oral glucose and intravenous glucagon in cystic fibrosis patients with normal, impaired, and diabetic glucose tolerance.
Acta endocrinologica 1993;128(3):207-14.
1993: Heindorff H; Holst J J; Almdal T; Vilstrup H
Effect of glucagon immunoneutralization on the increase in urea synthesis after hysterectomy in rats.
European journal of clinical investigation 1993;23(3):166-70.
1993: Schmidt P; Rasmussen T N; Holst J J
Release of immunoreactive somatostatin, vasoactive intestinal polypeptide (VIP), and galanin during propulsive complexes in isolated pig ileum.
Peptides 1993;14(2):215-20.
1993: Rasmussen T N; Harling H; Thim L; Pierzynowski S; Weström B R; Holst J J
Regulation of secretion of pancreatic spasmolytic polypeptide from porcine pancreas.
The American journal of physiology 1993;264(1 Pt 1):G22-9.
1993: Holst J J; Rasmussen T N; Harling H; Schmidt P
Effect of intestinal inhibitory peptides on vagally induced secretion from isolated perfused porcine pancreas.
Pancreas 1993;8(1):80-7.
1992: Holst J J; Jørgensen P N; Rasmussen T N; Schmidt P
Somatostatin restraint of gastrin secretion in pigs revealed by monoclonal antibody immunoneutralization.
The American journal of physiology 1992;263(6 Pt 1):G908-12.
1992: Rasmussen T N; Raaberg L; Poulsen S S; Thim L; Holst J J
Immunohistochemical localization of pancreatic spasmolytic polypeptide (PSP) in the pig.
Histochemistry 1992;98(2):113-9.
1992: Rasmussen T N; Gregersen H; Harling H; Holst J J
Calcitonin gene-related peptide: effect on contractile activity and luminal cross-sectional area in the isolated, perfused porcine ileum.
Scandinavian journal of gastroenterology 1992;27(9):787-92.
1992: Holst J J; Skak-Nielsen T; Orskov C; Seier-Poulsen S
Vagal control of the release of somatostatin, vasoactive intestinal polypeptide, gastrin-releasing peptide, and HCl from porcine non-antral stomach.
Scandinavian journal of gastroenterology 1992;27(8):677-85.
1992: Shokouh-Amiri M H; Falholt K; Holst J J; Rahimi-Saber S; Orbaek Andersen H; Jensen S L
Pancreas endocrine function in pigs after segmental pancreas autotransplantation with either systemic or portal venous drainage.
Transplantation proceedings 1992;24(3):799-800.
1992: Schmidt P; Rasmussen T N; Holst J J
Nervous control of the release of substance P and neurokinin A from the isolated perfused porcine ileum.
Journal of the autonomic nervous system 1992;38(2):85-95.
1992: Messell T; Harling H; Poulsen S S; Bersani M; Holst J J
Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused, porcine ileum.
Regulatory peptides 1992;38(3):179-98.
1992: Larsen P J; Bersani M; Holst J J; Møller M; Mikkelsen J D
Distribution and characterization of different molecular products of pro-somatostatin in the hypothalamus and posterior pituitary lobe of the Mongolian gerbil (Meriones unguiculatus).
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(3):946-61.
1992: Orskov C; Andreasen J; Holst J J
All products of proglucagon are elevated in plasma from uremic patients.
The Journal of clinical endocrinology and metabolism 1992;74(2):379-84.
1992: Almdal T P; Holst J J; Heindorff H; Vilstrup H
Glucagon immunoneutralization in diabetic rats normalizes urea synthesis and decreases nitrogen wasting.
Diabetes 1992;41(1):12-6.
1992: Harling H; Holst J J
Circulating galanin: origin, metabolism, and pharmacokinetics in anesthetized pigs.
The American journal of physiology 1992;262(1 Pt 1):E52-7.
1992: Holst J J; Orskov C; Seier-Poulsen S
Somatostatin is an essential paracrine link in acid inhibition of gastrin secretion.
Digestion 1992;51(2):95-102.
1991: Ehrhart-Bornstein M; Bornstein S R; Scherbaum W A; Pfeiffer E F; Holst J J
Role of the vasoactive intestinal peptide in a neuroendocrine regulation of the adrenal cortex.
Neuroendocrinology 1991;54(6):623-8.
1991: Bersani M; Thim L; Rasmussen T N; Holst J J
Galanin and galanin extended at the N-terminus with seven and nine amino acids are produced in and secreted from the porcine adrenal medulla in almost equal amounts.
Endocrinology 1991;129(5):2693-8.
1991: Messell T; Dunning B E; Sheikh S; Holst J J
Neuropeptide Y (NPY) and vasoactive intestinal polypeptide (VIP), but not galanin, are autonomic cotransmitters in the porcine pancreas.
International journal of pancreatology : official journal of the International Association of Pancreatology 1991;10(2):133-41.
1991: Schmidt P; Poulsen S S; Rasmussen T N; Bersani M; Holst J J
Substance P and neurokinin A are codistributed and colocalized in the porcine gastrointestinal tract.
Peptides 1991;12(5):963-73.
1991: Bjørnskov-Bartholdy L; Bersani M; Holst J J
Identification, characterization and release of GRP gene-associated peptides from the normal porcine and human gastro-intestinal tract.
Regulatory peptides 1991;34(3):197-209.
1991: Holst J J; Ehrhart-Bornstein M; Messell T; Poulsen S S; Harling H
Release of galanin from isolated perfused porcine adrenal glands: role of splanchnic nerves.
The American journal of physiology 1991;261(1 Pt 1):E31-40.
1991: Bersani M; Johnsen A H; Højrup P; Dunning B E; Andreasen J J; Holst J J
Human galanin: primary structure and identification of two molecular forms.
FEBS letters 1991;283(2):189-94.
1991: Schjoldager B; Poulsen S S; Schmidt P; Coy D H; Holst J J
Gastrin-releasing peptide is a transmitter mediating porcine gallbladder contraction.
The American journal of physiology 1991;260(4 Pt 1):G577-85.
1991: Orskov C; Jeppesen J; Madsbad S; Holst J J
Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine.
The Journal of clinical investigation 1991;87(2):415-23.
1991: Bersani M; Johnsen A H; Holst J J
Oxidation/reduction explains heterogeneity of pancreatic somatostatin.
FEBS letters 1991;279(2):237-9.
1991: Harling H; Messell T; Poulsen S S; Rasmussen T N; Holst J J
Galanin and vasoactive intestinal polypeptide: coexistence and corelease from the vascularly perfused pig ileum during distension and chemical stimulation of the mucosa.
Digestion 1991;50(2):61-71.
1990: Larsen J N; Bersani M; Olcese J; Holst J J; Møller M
Somatostatin and prosomatostatin in the retina of the rat: an immunohistochemical, in-situ hybridization, and chromatographic study.
Visual neuroscience 1990;5(5):441-52.
1990: Holst J J
Neuronal control of pancreatic exocrine secretion.
European journal of clinical investigation 1990;20 Suppl 1():S33-9.
1990: Holst J J; Schaffalitzky de Muckadell O B; Fahrenkrug J
Somatostatin inhibits neurally stimulated pancreatic secretion indirectly.
Pancreas 1990;5(5):611-4.
1990: Bornstein S R; Ehrhart-Bornstein M; Scherbaum W A; Pfeiffer E F; Holst J J
Effects of splanchnic nerve stimulation on the adrenal cortex may be mediated by chromaffin cells in a paracrine manner.
Endocrinology 1990;127(2):900-6.
1990: Holst J J; Ostenson C G; Harling H; Messell T
Porcine pancreastatin has no effect on endocrine secretion from the pig pancreas.
Diabetologia 1990;33(7):403-6.
1990: Shokouh-Amiri M H; Lindkaer S; Holst J J; Vagn Nielsen O; Sanchez-Almeyra R; Lauritsen K B
Glucagon response to hypoglycemia and the effect of oral glucose tolerance test on gastric inhibitory polypeptide secretion in pancreas transplanted pigs.
Transplantation proceedings 1990;22(2):729-31.
1990: Messell T; Harling H; Böttcher G; Johnsen A H; Holst J J
Galanin in the porcine pancreas.
Regulatory peptides 1990;28(2):161-76.
1990: Holst J J; Harling H; Messell T; Coy D H
Identification of the neurotransmitter/neuromodulator functions of the neuropeptide gastrin-releasing peptide in the porcine antrum, using the antagonist (Leu13-psi-CH2 NH-Leu14)-bombesin.
Scandinavian journal of gastroenterology 1990;25(1):89-96.
1990: Rasmussen T N; Thim L; Raaberg L; Harling H; Holst J J
Pancreatic spasmolytic polypeptide, a potential growth factor for the intestine: neural control of secretion.
Digestion 1990;46 Suppl 2():226-31.
1990: Harling H; Gregersen H; Rasmussen T N; Poulsen S S; Holst J J; Jenson S L
Galanin: distribution and effect on contractile activity and release of vasoactive intestinal polypeptide from the isolated perfused porcine ileum.
Digestion 1990;47(4):191-9.
1989: Holst J J; Hansen M; Bork E; Schwartz T W
Elevated plasma concentrations of C-flanking gastrin-releasing peptide in small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(12):1831-8.
1989: Schjoldager B; Mortensen P E; Myhre J; Christiansen J; Holst J J
Oxyntomodulin from distal gut. Role in regulation of gastric and pancreatic functions.
Digestive diseases and sciences 1989;34(9):1411-9.
1989: Orskov C; Bersani M; Johnsen A H; Højrup P; Holst J J
Complete sequences of glucagon-like peptide-1 from human and pig small intestine.
The Journal of biological chemistry 1989;264(22):12826-9.
1989: Holst J J; Orskov C; Knuhtsen S; Sheikh S; Nielsen O V
On the regulatory functions of neuropeptide Y (NPY) with respect to vascular resistance and exocrine and endocrine secretion in the pig pancreas.
Acta physiologica Scandinavica 1989;136(4):519-26.
1989: Bersani M; Thim L; Baldissera F G; Holst J J
Prosomatostatin 1-64 is a major product of somatostatin gene expression in pancreas and gut.
The Journal of biological chemistry 1989;264(18):10633-6.
1989: Schjoldager B T; Mortensen P E; Christiansen J; Orskov C; Holst J J
GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans.
Digestive diseases and sciences 1989;34(5):703-8.
1989: Orskov C; Buhl T; Rabenhøj L; Kofod H; Holst J J
Carboxypeptidase-B-like processing of the C-terminus of glucagon-like peptide-2 in pig and human small intestine.
FEBS letters 1989;247(2):193-6.
1989: Holst J J; Knuhtsen S; Nielsen O V
Role of gastrin-releasing peptide in neural control of pancreatic exocrine secretion.
Pancreas 1989;4(5):581-6.
1989: Harling H; Messell T; Jensen S L; Holst J J; Poulsen S S
Occurrence, distribution and motor effects of galanin in the porcine lower esophageal sphincter.
Digestion 1989;42(3):151-7.
1988: Skak-Nielsen T; Holst J J; Nielsen O V
Role of gastrin-releasing peptide in the neural control of pepsinogen secretion from the pig stomach.
Gastroenterology 1988;95(5):1216-20.
1988: Schjoldager B T; Baldissera F G; Mortensen P E; Holst J J; Christiansen J
Oxyntomodulin: a potential hormone from the distal gut. Pharmacokinetics and effects on gastric acid and insulin secretion in man.
European journal of clinical investigation 1988;18(5):499-503.
1988: Orskov C; Holst J J; Nielsen O V
Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach.
Endocrinology 1988;123(4):2009-13.
1988: Sheikh S P; Holst J J; Skak-Nielsen T; Knigge U; Warberg J; Theodorsson-Norheim E; Hökfelt T; Lundberg J M; Schwartz T W
Release of NPY in pig pancreas: dual parasympathetic and sympathetic regulation.
The American journal of physiology 1988;255(1 Pt 1):G46-54.
1988: Buhl T; Thim L; Kofod H; Orskov C; Harling H; Holst J J
Naturally occurring products of proglucagon 111-160 in the porcine and human small intestine.
The Journal of biological chemistry 1988;263(18):8621-4.
1988: Holst Pedersen J; Knuthsen S; Bernabei M; Orskov C; Holst J J
Secretion of neurotensin from isolated perfused porcine ileum.
Regulatory peptides 1988;21(1-2):13-9.
1988: Loud F B; Holst J J; Rehfeld J F; Christiansen J
Inhibition of gastric acid secretion in humans by glucagon during euglycemia, hyperglycemia, and hypoglycemia.
Digestive diseases and sciences 1988;33(5):530-4.
1988: Baldissera F G; Holst J J; Knuhtsen S; Hilsted L; Nielsen O V
Oxyntomodulin (glicentin-(33-69)): pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs.
Regulatory peptides 1988;21(1-2):151-66.
1988: Loud F B; Holst J J; Christiansen J; Rehfeld J F
Effect of glucagon on vagally induced gastric acid secretion in humans.
Digestive diseases and sciences 1988;33(4):405-8.
1988: Gehl J; Jeppesen J L; Poulsen S S; Holst J J
The gastric acid secretagogue gastrin-releasing peptide and the inhibitor oxyntomodulin do not exert their effect directly on the parietal cell in the rat.
Digestion 1988;40(3):144-51.
1988: Holst J J; Knuhtsen S; Skak-Nielsen T
The role of gastrin-releasing peptide in pancreatic exocrine secretion.
Annals of the New York Academy of Sciences 1988;547():234-41.
1988: Holst J J; Baldissera F G; Bersani M; Skak-Nielsen T; Seier-Poulsen S; Nielsen O V
Processing and secretion of prosomatostatin by the pig pancreas.
Pancreas 1988;3(6):653-61.
1987: Holst J J; Knuhtsen S; Orskov C; Skak-Nielsen T; Poulsen S S; Nielsen O V
GRP-producing nerves control antral somatostatin and gastrin secretion in pigs.
The American journal of physiology 1987;253(6 Pt 1):G767-74.
1987: Orskov C; Holst J J; Poulsen S S; Kirkegaard P
Pancreatic and intestinal processing of proglucagon in man.
Diabetologia 1987;30(11):874-81.
1987: Skak-Nielsen T; Holst J J; Baldissera F G; Poulsen S S
Localization in the gastrointestinal tract of immunoreactive prosomatostatin.
Regulatory peptides 1987;19(3-4):183-95.
1987: Holst J J; Knuhtsen S; Orskov C; Skak-Nielsen T; Poulsen S S; Jensen S L; Nielsen O V
GRP nerves in pig antrum: role of GRP in vagal control of gastrin secretion.
The American journal of physiology 1987;253(5 Pt 1):G643-9.
1987: Knuhtsen S; Holst J J; Baldissera F G; Skak-Nielsen T; Poulsen S S; Jensen S L; Nielsen O V
Gastrin-releasing peptide in the porcine pancreas.
Gastroenterology 1987;92(5 Pt 1):1153-8.
1987: Holst J J
Does the endocrine secretion of the pancreas exert a local control of the exocrine secretion?
Pancreas 1987;2(5):613-9.
1986: Orskov C; Holst J J; Knuhtsen S; Baldissera F G; Poulsen S S; Nielsen O V
Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas.
Endocrinology 1986;119(4):1467-75.
1985: Baldissera F G; Nielsen O V; Holst J J
The intestinal mucosa preferentially releases somatostatin-28 in pigs.
Regulatory peptides 1985;11(3):251-62.

Sign-in to see more