FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Ulrike Holzgrabe

Research Profile

Chemicals & Drugs

Procedures

Concepts & Ideas

Phenomena

Co-author Network

Publications

TOP 3
R Schrage; Wk Seemann; Kurt Racké; Clelia Dallanoce; Marco De Amici; Ulrike Holzgrabe; J Klöckner; Evi Kostenis; Klaus Mohr
Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor.
Stefan Laufer; Ulrike Holzgrabe; Dieter Steinhilber
Drug discovery: a modern decathlon.
Klaus Mohr; Jens Schmitz; Ramona Schrage; Christian Tränkle; Ulrike Holzgrabe
Molecular alliance-from orthosteric and allosteric ligands to dualsteric/bitopic agonists at G protein coupled receptors.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Ulrike Holzgrabe (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: R Schrage; Wk Seemann; Kurt Racké; Clelia Dallanoce; Marco De Amici; Ulrike Holzgrabe; J Klöckner; Evi Kostenis; Klaus Mohr
Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor.
British journal of pharmacology 2013;169(2):357-70.
2013: Stefan Laufer; Ulrike Holzgrabe; Dieter Steinhilber
Drug discovery: a modern decathlon.
Angewandte Chemie (International ed. in English) 2013;52(15):4072-6.
2013: Klaus Mohr; Jens Schmitz; Ramona Schrage; Christian Tränkle; Ulrike Holzgrabe
Molecular alliance-from orthosteric and allosteric ligands to dualsteric/bitopic agonists at G protein coupled receptors.
Angewandte Chemie (International ed. in English) 2013;52(2):508-16.
2013: Claudia Borst; Ulrike Holzgrabe
Cyclodextrin-mediated enantioseparation in microemulsion electrokinetic chromatography.
Methods in molecular biology (Clifton, N.J.) 2013;970():363-75.
2012: Cornelia Landersdorfer; Ulrich Stephan; Jürgen Bulitta; George L Drusano; Ulrike Holzgrabe; Martina Kinzig; Carl M J Kirkpatrick; Fritz Sörgel
Population pharmacokinetics of piperacillin at two dose levels: influence of nonlinear pharmacokinetics on the pharmacodynamic profile.
Antimicrobial agents and chemotherapy 2012;56(11):5715-23.
2012: Stefan Almeling; David Ilko; Ulrike Holzgrabe
Charged aerosol detection in pharmaceutical analysis.
Journal of pharmaceutical and biomedical analysis 2012;69():50-63.
2012: Ludwig Hoellein; Ulrike Holzgrabe
Ficts and facts of epinephrine and norepinephrine stability in injectable solutions.
International journal of pharmaceutics 2012;434(1-2):468-80.
2012: Ulrike Holzgrabe; Marianne Abele-Horn
[MRSA--development, distribution and prevention].
Medizinische Monatsschrift für Pharmazeuten 2012;35(9):319-28; quiz 329-30.
2012: Ulrike Holzgrabe
[Inhibitors of the New Delhi-Metallolactamase].
Pharmazie in unserer Zeit 2012;41(4):270.
2012: Michalina Ignasik; Marek Bajda; Natalia Guzior; Ulrike Holzgrabe; Michaela Prinz; Barbara Malawska
Design, synthesis and evaluation of novel 2-(aminoalkyl)-isoindoline-1,3-dione derivatives as dual-binding site acetylcholinesterase inhibitors.
Archiv der Pharmazie 2012;345(7):509-16.
2012: David Ilko; Ulrike Holzgrabe
Influence of the capillary diameter on the separation efficiency and sensitivity: a systematic approach.
Electrophoresis 2012;33(11):1494-8.
2012: Georg Hiltensperger; Holger Braunschweig; Alexander Damme; Markus Engstler; Nicola G Jones; Jamin Jung; Marcel Kaiser; Lorenz Meinel; Sabine Niedermeier; Sebastian Puhl; August Stich; Ulrike Holzgrabe
Synthesis and structure-activity relationships of new quinolone-type molecules against Trypanosoma brucei.
Journal of medicinal chemistry 2012;55(6):2538-48.
2012: Marija Djukic; Helmut Eiffert; Ulrike Holzgrabe; Martin Munz; Fritz Sörgel; Roland Nau
Overton's rule helps to estimate the penetration of anti-infectives into patients' cerebrospinal fluid.
Antimicrobial agents and chemotherapy 2012;56(2):979-88.
2012: Andreas Hartung; Carsten Berges; Viktoria H Gessner; Florian Seufert; Ulrike Holzgrabe
One-pot Ugi/Aza-Michael synthesis of highly substituted 2,5-diketopiperazines with anti-proliferative properties.
Molecules (Basel, Switzerland) 2012;17(12):14685-99.
2012: Andreas Bock; Clelia Dallanoce; Marco De Amici; Carsten Hoffmann; Ulrike Holzgrabe; Anna Kebig; Jessica Klöckner; Evi Kostenis; Carlo Matera; Nicole Merten; Anke Müller; Lucas Peters; Jens Schmitz; Ramona Schrage; Jasmin Schrobang-Ley; Katharina Simon; Christian Tränkle; Julia Bätz; Klaus Mohr
The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling.
Nature communications 2012;3():1044.
2012: Christine M Topf; Caroline Kisker; Johannes Schiebel; Ulrike Holzgrabe
[Old and new anti-mycobacterial drugs. Fatty acid synthesis as a target].
Pharmazie in unserer Zeit 2012;41(1):64-70.
2012: Ulrike Holzgrabe
[FRET (Fluorescence Resonance Energy Transfer) for the determination of minimal inhibitory concentration of antibiotics].
Pharmazie in unserer Zeit 2012;41(1):6-7.
2012: Peter Imming; Martin Schlitzer; Ulrike Holzgrabe
[Editorial: Pharmazie in unserer Zeit 1/2012].
Pharmazie in unserer Zeit 2012;41(1):3.
2011: Jens Schmitz; Ulrike Holzgrabe
[The development of selective α2-receptor agonists].
Pharmazie in unserer Zeit 2011;40(6):496-502.
2011: Ulrike Holzgrabe
[Nature as a pharmacy against tropical diseases: Tirandamycin B against lymphatic filariasis].
Pharmazie in unserer Zeit 2011;40(6):450-1.
2011: Lutz Hein; Ulrike Holzgrabe
[Editorial: Pharmazie in unserer Zeit 6/2011].
Pharmazie in unserer Zeit 2011;40(6):447.
2011: Ulrike Holzgrabe; Nathalie Kunz; Cees-Jan Nap; Stefan Almeling
Identification and control of impurities in streptomycin sulfate by high-performance liquid chromatography coupled with mass detection and corona charged-aerosol detection.
Journal of pharmaceutical and biomedical analysis 2011;56(2):271-9.
2011: Ulrike Holzgrabe; Cees-Jan Nap; Stefan Almeling
Use of collision induced dissociation mass spectrometry as a rapid technique for the identification of pharmacologically active peptides in pharmacopoeial testing.
Journal of pharmaceutical and biomedical analysis 2011;55(5):957-63.
2011: Ulrike Holzgrabe; Myriam Malet-Martino
Analytical challenges in drug counterfeiting and falsification-The NMR approach.
Journal of pharmaceutical and biomedical analysis 2011;55(4):679-87.
2011: C Büttner-Merz; Ulrike Holzgrabe
How to evaluate the separation efficiency of CZE methods?
Pharmeuropa bio & scientific notes 2011;2011(1):81-8.
2011: Paul W Elsinghorst; Martina Kinzig; Michael Rodamer; Ulrike Holzgrabe; Fritz Sörgel
An LC-MS/MS procedure for the quantification of naproxen in human plasma: development, validation, comparison with other methods, and application to a pharmacokinetic study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2011;879(19):1686-96.
2011: Jürgen Bulitta; Martina Kinzig; Cornelia Landersdorfer; Ulrike Holzgrabe; U Stephan; Fritz Sörgel
Comparable population pharmacokinetics and pharmacodynamic breakpoints of cefpirome in cystic fibrosis patients and healthy volunteers.
Antimicrobial agents and chemotherapy 2011;55(6):2927-36.
2011: Eva Kugelmann; Christian R Albert; Gerhard Bringmann; Ulrike Holzgrabe
Fenton's oxidation: a tool for the investigation of potential drug metabolites.
Journal of pharmaceutical and biomedical analysis 2011;54(5):1047-58.
2011: Subhalakshmi Ghosh; Sukalyani Debnath; Sudipta Hazra; Andreas Hartung; Katja Thomale; Martina Schultheis; Petra Kapkova; Uta Schurigt; Heidrun Moll; Ulrike Holzgrabe; Banasri Hazra
Valeriana wallichii root extracts and fractions with activity against Leishmania spp.
Parasitology research 2011;108(4):861-71.
2011: Ulrike Holzgrabe
[How safe was oseltamivir care in the flu pandemic?].
Pharmazie in unserer Zeit 2011;40(2):151-4.
2011: Ulrike Holzgrabe; Martin Schlitzer; Torsten Steinmetzer
[Pharmazie in unserer Zeit 2/2011].
Pharmazie in unserer Zeit 2011;40(2):95.
2011: Christina Juli; Paul Rösch; Kristian Schweimer; Martin Sippel; Christoph A Sotriffer; Michael Steinert; Alexandra Thiele; Matthias Weiwad; Jens Jäger; Ulrike Holzgrabe
Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein.
Journal of medicinal chemistry 2011;54(1):277-83.
2011: Alexander Cecil; Jörg Bernhardt; Gerhard Bringmann; Tobias A M Gulder; Ulrike Holzgrabe; Chunguang Liang; Tobias A Oelschlaeger; Knut Ohlsen; Carina Rikanović; Matthias Unger; Thomas Dandekar
Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells.
Genome biology 2011;12(3):R24.
2011: Thomas M Menzel; Maximilian Tischer; Patrice François; Joachim Nickel; Jacques Schrenzel; Heike Bruhn; Annette Albrecht; Leane Lehmann; Ulrike Holzgrabe; Knut Ohlsen
Mode-of-action studies of the novel bisquaternary bisnaphthalimide MT02 against Staphylococcus aureus.
Antimicrobial agents and chemotherapy 2011;55(1):311-20.
2011: Susanne Alban; Susanne Lühn; Simone Schiemann; Tanja Beyer; Jochen Norwig; Claudia Schilling; Oliver Rädler; Bernhard Wolf; Magnus Matz; Knut Baumann; Ulrike Holzgrabe
Comparison of established and novel purity tests for the quality control of heparin by means of a set of 177 heparin samples.
Analytical and bioanalytical chemistry 2011;399(2):605-20.
2010: Claudia Borst; Ulrike Holzgrabe
Comparison of chiral electrophoretic separation methods for phenethylamines and application on impurity analysis.
Journal of pharmaceutical and biomedical analysis 2010;53(5):1201-9.
2010: Jürgen Bulitta; Martina Kinzig; Verena Jakob; Ulrike Holzgrabe; Fritz Sörgel; Nicholas H G Holford
Nonlinear pharmacokinetics of piperacillin in healthy volunteers--implications for optimal dosage regimens.
British journal of clinical pharmacology 2010;70(5):682-93.
2010: Jens Schmitz; Ulrike Holzgrabe
[PAH and many other indications. Old and new endothelin receptor antagonists.].
Pharmazie in unserer Zeit 2010;39(6):430-5.
2010: Ulrike Holzgrabe
[Return to the pre-Semmelweis-age - MRSA, NDM-1 and what is to come?].
Pharmazie in unserer Zeit 2010;39(6):426-7.
2010: Ulrike Holzgrabe; Klaus Mohr
[The blood circulating in the body is distributed by a richly branched vasculature to tissues and organs].
Pharmazie in unserer Zeit 2010;39(6):423.
2010: K Singethan; G Hiltensperger; S Kendl; J Wohlfahrt; P Plattet; Ulrike Holzgrabe; Jürgen Schneider-Schaulies
N-(3-Cyanophenyl)-2-phenylacetamide, an effective inhibitor of morbillivirus-induced membrane fusion with low cytotoxicity.
The Journal of general virology 2010;91(Pt 11):2762-72.
2010: Jens Schmitz; Ulrike Holzgrabe
[Plectasin - a new peptide antibiotic with high therapeutic potential].
Pharmazie in unserer Zeit 2010;39(5):336-8.
2010: Jens Schmitz; Ulrike Holzgrabe
[XF-73 - a new antibacterial lead compound].
Pharmazie in unserer Zeit 2010;39(5):335-6.
2010: Ulrike Holzgrabe
[Large-scale attack against Plasmodium].
Pharmazie in unserer Zeit 2010;39(5):334-5.
2010: Ulrike Holzgrabe
Quantitative NMR spectroscopy in pharmaceutical applications.
Progress in nuclear magnetic resonance spectroscopy 2010;57(2):229-40.
2010: Ulrike Holzgrabe; Cees-Jan Nap; Tanja Beyer; Stefan Almeling
Alternatives to amino acid analysis for the purity control of pharmaceutical grade L-alanine.
Journal of separation science 2010;33(16):2402-10.
2010: Tanja Beyer; Magnus Matz; Daniela Brinz; Oliver Rädler; Bernhard Wolf; Jochen Norwig; Knut Baumann; Susanne Alban; Ulrike Holzgrabe
Composition of OSCS-contaminated heparin occurring in 2008 in batches on the German market.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;40(4):297-304.
2010: Ulrike Holzgrabe
[Trypanosomes in focus].
Pharmazie in unserer Zeit 2010;39(4):261-2.
2010: Ulrike Holzgrabe
[Alternative paths to multidrug-resistant bacteria via reactive oxygen species].
Pharmazie in unserer Zeit 2010;39(4):260-1.
2010: Maximilian Tischer; Ludmilla Sologub; Gabriele Pradel; Ulrike Holzgrabe
The bisnaphthalimides as new active lead compounds against Plasmodium falciparum.
Bioorganic & medicinal chemistry 2010;18(9):2998-3003.
2010: Tanja Beyer; Curd Schollmayer; Ulrike Holzgrabe
The role of solvents in the signal separation for quantitative (1)H NMR spectroscopy.
Journal of pharmaceutical and biomedical analysis 2010;52(1):51-8.
2010: Marco De Amici; Clelia Dallanoce; Ulrike Holzgrabe; Christian Tränkle; Klaus Mohr
Allosteric ligands for G protein-coupled receptors: a novel strategy with attractive therapeutic opportunities.
Medicinal research reviews 2010;30(3):463-549.
2010: Stefan Almeling; Ulrike Holzgrabe
Use of evaporative light scattering detection for the quality control of drug substances: influence of different liquid chromatographic and evaporative light scattering detector parameters on the appearance of spike peaks.
Journal of chromatography. A 2010;1217(14):2163-70.
2010: Jens Schmitz; Ulrike Holzgrabe
[Amadacyclin - a new tetracycline antibiotic in the pipeline].
Pharmazie in unserer Zeit 2010;39(2):94-5.
2010: Ulrike Holzgrabe
[Dual attack on the gyrase by simocyclinone].
Pharmazie in unserer Zeit 2010;39(2):95-6.
2010: Vildan Alptüzün; Michaela Prinz; Verena Hörr; Josef Scheiber; Krzysztof Radacki; Adyary Fallarero; Pia Vuorela; Bernd Engels; Holger Braunschweig; Ercin Erciyas; Ulrike Holzgrabe
Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with beta-amyloid, acetylcholine, and butyrylcholine esterases.
Bioorganic & medicinal chemistry 2010;18(5):2049-59.
2010: Klaus Mohr; Christian Tränkle; Evi Kostenis; Elisabetta Barocelli; Marco De Amici; Ulrike Holzgrabe
Rational design of dualsteric GPCR ligands: quests and promise.
British journal of pharmacology 2010;159(5):997-1008.
2010: Cornelia Landersdorfer; Carl M J Kirkpatrick; Martina Kinzig; Jürgen Bulitta; Ulrike Holzgrabe; Ulrich Jaehde; Andreas Reiter; Kurt G Naber; Michael Rodamer; Fritz Sörgel
Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid.
British journal of clinical pharmacology 2010;69(2):167-78.
2010: Ulrike Holzgrabe; Cees-Jan Nap; Stefan Almeling
Control of impurities in L-aspartic acid and L-alanine by high-performance liquid chromatography coupled with a corona charged aerosol detector.
Journal of chromatography. A 2010;1217(3):294-301.
2010: Abdullah Aydın; Mehmet Akkurt; Vildan Alptüzün; Orhan Büyükgüngör; Ulrike Holzgrabe; Krzysztof Radacki
4-[(2E)-2-(4-Chloro-benzyl-idene)hydrazinyl-idene]-1-methyl-1,4-dihydro-pyridine monohydrate.
Acta crystallographica. Section E, Structure reports online 2010;66(Pt 6):o1324-5.
2010: Edith Bennack; Ulrike Holzgrabe
[Emergency admission of peramivir in the U.S.A].
Pharmazie in unserer Zeit 2010;39(1):9-10.
2009: Guillermo Montoya; Gabriel J Arango; Matthias Unger; Ulrike Holzgrabe
O-glycoside sequence of pentacyclic triterpene saponins from Phytolacca bogotensis using HPLC-ESI/multi-stage tandem mass spectrometry.
Phytochemical analysis : PCA 2009;20(6):465-74.
2009: Jürgen B Bulitta; Stephen B Duffull; Cornelia Landersdorfer; Martina Kinzig; Ulrike Holzgrabe; Ulrich Stephan; George L Drusano; Fritz Sörgel
Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers.
Diagnostic microbiology and infectious disease 2009;65(2):130-41.
2009: Cornelia Landersdorfer; Carl M J Kirkpatrick; Martina Kinzig; Jürgen Bulitta; Ulrike Holzgrabe; George L Drusano; Fritz Sörgel
Competitive inhibition of renal tubular secretion of gemifloxacin by probenecid.
Antimicrobial agents and chemotherapy 2009;53(9):3902-7.
2009: Jürgen Bulitta; Cornelia Landersdorfer; Martina Kinzig; Ulrike Holzgrabe; F Sorgel
New semiphysiological absorption model to assess the pharmacodynamic profile of cefuroxime axetil using nonparametric and parametric population pharmacokinetics.
Antimicrobial agents and chemotherapy 2009;53(8):3462-71.
2009: Sabine Niedermeier; Katrin Singethan; Sebastian G Rohrer; Magnus Matz; Markus Kossner; Sandra Diederich; Andrea Maisner; Jens Schmitz; Georg Hiltensperger; Knut Baumann; Ulrike Holzgrabe; Jürgen Schneider-Schaulies
A small-molecule inhibitor of Nipah virus envelope protein-mediated membrane fusion.
Journal of medicinal chemistry 2009;52(14):4257-65.
2009: Ulrike Holzgrabe
Meropenem-clavulanate: a new strategy for the treatment of tuberculosis?
ChemMedChem 2009;4(7):1051-3.
2009: Benjamin Waibel; Christoph Albert; Ulrike Holzgrabe
Evaluation of the extent of protein binding by means of NMR diffusion and relaxation experiments, and automated continuous ultrafiltration.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;37(3-4):191-7.
2009: Cornelia Landersdorfer; Martina Kinzig; Jürgen Bulitta; Friedrich F Hennig; Ulrike Holzgrabe; Fritz Sörgel; Johannes Gusinde
Bone penetration of amoxicillin and clavulanic acid evaluated by population pharmacokinetics and Monte Carlo simulation.
Antimicrobial agents and chemotherapy 2009;53(6):2569-78.
2009: Cornelia Landersdorfer; Martina Kinzig; Friedrich F Hennig; Jürgen Bulitta; Ulrike Holzgrabe; George L Drusano; Fritz Sörgel; Johannes Gusinde
Penetration of moxifloxacin into bone evaluated by Monte Carlo simulation.
Antimicrobial agents and chemotherapy 2009;53(5):2074-81.
2009: Hany Ghaly; Christine Kriete; Seher Sahin; Anja Pflöger; Ulrike Holzgrabe; Bernd Joachim Zünkler; Ingo Rustenbeck
The insulinotropic effect of fluoroquinolones.
Biochemical pharmacology 2009;77(6):1040-52.
2009: J Norwig; T Beyer; D Brinz; Ulrike Holzgrabe; M Diller; D Manns
Prediction of the oversulphated chondroitin sulphate contamination of unfractionated heparin by ATR-IR spectrophotometry.
Pharmeuropa scientific notes 2009;2009(1):17-24.
2009: Florian Diwischek; Joachim Morschhäuser; Ulrike Holzgrabe
Cerulenin analogues as inhibitors of efflux pumps in drug-resistant Candida albicans.
Archiv der Pharmazie 2009;342(3):150-64.
2009: Alicia Ponte-Sucre; Tobias A M Gulder; Annemarie Wegehaupt; Christoph Albert; Carina Rikanović; Leonhard Schaeflein; Andreas Frank; Martina Schultheis; Matthias Unger; Ulrike Holzgrabe; Gerhard Bringmann; Heidrun Moll
Structure-activity relationship and studies on the molecular mechanism of leishmanicidal N,C-coupled arylisoquinolinium salts.
Journal of medicinal chemistry 2009;52(3):626-36.
2009: Johannes Antony; Kerstin Kellershohn; Marion Mohr-Andrä; Anna Kebig; Stefanie Prilla; Mathias Muth; Eberhard Heller; Teresa Disingrini; Clelia Dallanoce; Simona Bertoni; Jasmin Schrobang; Christian Tränkle; Evi Kostenis; Arthur Christopoulos; Hans-Dieter Höltje; Elisabetta Barocelli; Marco De Amici; Ulrike Holzgrabe; Klaus Mohr
Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(2):442-50.
2009: Ulrike Holzgrabe
[Problem of counterfeit medicines in Africa and Southeast Asia. Fake anti-malaria drugs and more].
Pharmazie in unserer Zeit 2009;38(6):560-2.
2009: Ulrike Holzgrabe
[A way out of a malaria-resistance?].
Pharmazie in unserer Zeit 2009;38(6):487-8.
2009: Ulrike Holzgrabe
[New hope for malaria vaccine].
Pharmazie in unserer Zeit 2009;38(6):486-7.
2009: Ulrike Holzgrabe; Martin Schlitzer; August Stich
[Editorial: Pharmazie in unserer Zeit 6/2009 ].
Pharmazie in unserer Zeit 2009;38(6):483.
2009: Cornelia Landersdorfer; Jürgen Bulitta; Martina Kinzig; Ulrike Holzgrabe; Fritz Sörgel
Penetration of antibacterials into bone: pharmacokinetic, pharmacodynamic and bioanalytical considerations.
Clinical pharmacokinetics 2009;48(2):89-124.
2009: Ulrike Holzgrabe
[Everything is in flux. Vitamin E].
Pharmazie in unserer Zeit 2009;38(2):132-5.
2009: Ulrike Holzgrabe
[New antibiotics in sight?].
Pharmazie in unserer Zeit 2009;38(2):106-8.
2008: Cornelia Landersdorfer; Carl M J Kirkpatrick; Martina Kinzig; Jürgen Bulitta; Ulrike Holzgrabe; Fritz Sörgel
Inhibition of flucloxacillin tubular renal secretion by piperacillin.
British journal of clinical pharmacology 2008;66(5):648-59.
2008: Claudia Borst; Ulrike Holzgrabe
Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography.
Journal of chromatography. A 2008;1204(2):191-6.
2008: T Beyer; B Diehl; G Randel; E Humpfer; H Schäfer; Manfred Spraul; C Schollmayer; Ulrike Holzgrabe
Quality assessment of unfractionated heparin using 1H nuclear magnetic resonance spectroscopy.
Journal of pharmaceutical and biomedical analysis 2008;48(1):13-9.
2008: Daniela Brinz; Ulrike Holzgrabe
Analysis of the molecular size distribution of polyethylene glycols by CE-UV versus HPLC with evaporative light scattering detection.
Electrophoresis 2008;29(17):3605-11.
2008: Tim Goebel; Daniela Ulmer; Holger Projahn; Jessica Kloeckner; Eberhard Heller; Melanie Glaser; Alicia Ponte-Sucre; Sabine Specht; Salem Ramadan Sarite; Achim Hoerauf; Annette Kaiser; Ilona Hauber; Joachim Hauber; Ulrike Holzgrabe
In search of novel agents for therapy of tropical diseases and human immunodeficiency virus.
Journal of medicinal chemistry 2008;51(2):238-50.
2008: Ulrike Holzgrabe; Andrea Sinz
[Alpha blockers and 5-alpha reductase inhibitors].
Pharmazie in unserer Zeit 2008;37(4):273.
2008: Ulrike Holzgrabe; Edith Bennack
[5-Alpha reductase inhibitors--benign prostatic hypertrophy and much more].
Pharmazie in unserer Zeit 2008;37(4):310-4.
2008: Ulrike Holzgrabe; Stefanie Laug; Frank Wienen
Micellar electrokinetic chromatography of aminoglycosides.
Methods in molecular biology (Clifton, N.J.) 2008;384():735-49.
2008: Ulrike Holzgrabe; Manfred Schubert-Zsilavecz
[Helping ourselves to promote our scientific advancement].
Pharmazie in unserer Zeit 2008;37(1):97.
2008: Ulrike Holzgrabe
[Statement of accounts].
Pharmazie in unserer Zeit 2008;37(1):94-5.
2007: Dorothea Jäger; Caroline Schmalenbach; Stefanie Prilla; Jasmin Schrobang; Anna Kebig; Matthias Sennwitz; Eberhard Heller; Christian Tränkle; Ulrike Holzgrabe; Hans-Dieter Höltje; Klaus Mohr
Allosteric small molecules unveil a role of an extracellular E2/transmembrane helix 7 junction for G protein-coupled receptor activation.
The Journal of biological chemistry 2007;282(48):34968-76.
2007: Verena Hoerr; Wilma Ziebuhr; Svetlana Kozitskaya; Elena Katzowitsch; Ulrike Holzgrabe
Laser-induced fluorescence-capillary electrophoresis and fluorescence microplate reader measurement: two methods to quantify the effect of antibiotics.
Analytical chemistry 2007;79(19):7510-8.
2007: Cornelia Landersdorfer; Carl M J Kirkpatrick; Martina Kinzig; Jürgen Bulitta; Ulrike Holzgrabe; George L Drusano; Fritz Sörgel
Population pharmacokinetics at two dose levels and pharmacodynamic profiling of flucloxacillin.
Antimicrobial agents and chemotherapy 2007;51(9):3290-7.
2007: Yaser Bitar; Ulrike Holzgrabe
Enantioseparation of chiral tropa alkaloids by means of cyclodextrin-modified microemulsion electrokinetic chromatography.
Electrophoresis 2007;28(15):2693-700.
2007: Yaser Bitar; Ulrike Holzgrabe
Impurity profiling of atropine sulfate by microemulsion electrokinetic chromatography.
Journal of pharmaceutical and biomedical analysis 2007;44(3):623-33.
2007: Susanne Kopec; Ulrike Holzgrabe
Amino acids: aspects of impurity profiling by means of CE.
Electrophoresis 2007;28(13):2153-67.
2007: Jürgen Bulitta; S B Duffull; Martina Kinzig; Ulrike Holzgrabe; U Stephan; George L Drusano; Fritz Sörgel
Systematic comparison of the population pharmacokinetics and pharmacodynamics of piperacillin in cystic fibrosis patients and healthy volunteers.
Antimicrobial agents and chemotherapy 2007;51(7):2497-507.
2007: Ulrike Holzgrabe; Mathias Muth
[Chronic obstructive pulmonary disease].
Medizinische Monatsschrift für Pharmazeuten 2007;30(5):168-76; quiz 177-8.
2007: Ute Neugebauer; Ulrike Schmid; Knut Baumann; Wilma Ziebuhr; Svetlana Kozitskaya; Ulrike Holzgrabe; Michael Schmitt; Jürgen Popp
The influence of fluoroquinolone drugs on the bacterial growth of S. epidermidis utilizing the unique potential of vibrational spectroscopy.
The journal of physical chemistry. A 2007;111(15):2898-906.
2007: Benjamin Waibel; Ulrike Holzgrabe
1H and 19F NMR relaxation studies of fleroxacin with Micrococcus luteus.
Journal of pharmaceutical and biomedical analysis 2007;43(5):1595-601.
2007: Mathias Muth; Verena Hoerr; Melanie Glaser; Alicia Ponte-Sucre; Heidrun Moll; August Stich; Ulrike Holzgrabe
Antitrypanosomal activity of quaternary naphthalimide derivatives.
Bioorganic & medicinal chemistry letters 2007;17(6):1590-3.
2007: Ulrike Holzgrabe; Petra Kapková; Vildan Alptüzün; Josef Scheiber; Eva Kugelmann
Targeting acetylcholinesterase to treat neurodegeneration.
Expert opinion on therapeutic targets 2007;11(2):161-79.
2007: A Deubel; Ulrike Holzgrabe
Development of an enhanced separation of erythromycin and its related substances by liquid chromatography.
Journal of pharmaceutical and biomedical analysis 2007;43(2):493-8.
2007: Ulrike Holzgrabe
[An old drug as a carcinostatic. The new career of thalidomide].
Pharmazie in unserer Zeit 2007;36(6):446-9.
2007: Ulrike Holzgrabe
[Lactivicin--an antibiotic against penicillin-resistant pneumococci].
Pharmazie in unserer Zeit 2007;36(6):421-2.
2007: Ulrike Holzgrabe
[Two flies with one blow--platencin, an new antibiotic].
Pharmazie in unserer Zeit 2007;36(6):418-9.
2007: Edith Bennack; Ulrike Holzgrabe
[H1-antihistaminics of the first generation].
Pharmazie in unserer Zeit 2007;36(3):202-4.
2006: A Deubel; A S Fandiño; F Sörgel; Ulrike Holzgrabe
Determination of erythromycin and related substances in commercial samples using liquid chromatography/ion trap mass spectrometry.
Journal of chromatography. A 2006;1136(1):39-47.
2006: Bernd J Zünkler; Sonja Claassen; Maria Wos-Maganga; Ingo Rustenbeck; Ulrike Holzgrabe
Effects of fluoroquinolones on HERG channels and on pancreatic beta-cell ATP-sensitive K+ channels.
Toxicology 2006;228(2-3):239-48.
2006: Susanne Kopec; S Almeling; Ulrike Holzgrabe
Determination of the impurity profile of adenosine by means of ion-pair reversed-phase chromatography.
Pharmeuropa scientific notes 2006;2006(2):17-21.
2006: A Kaiser; D Ulmer; T Goebel; Ulrike Holzgrabe; Michael Saeftel; Achim Hoerauf
Inhibition of hypusine biosynthesis in plasmodium: a possible, new strategy in prevention and therapy of malaria.
Mini reviews in medicinal chemistry 2006;6(11):1231-41.
2006: Verena Hoerr; Kerstin Hoffmann; Curd Schollmayer; Ulrike Holzgrabe; Axel Haase; Peter M Jakob; Cornelius Faber
Assessment of inhibitory potency of antibiotics by MRI: apparent T2 as a marker of cell growth.
Magma (New York, N.Y.) 2006;19(5):247-55.
2006: Petra Kapková; Eberhard Heller; Eva Kugelmann; Johan Faber; Gerhard Bringmann; Ulrich Kessler; Gerd Folkers; Ulrike Holzgrabe
Random chemistry as a new tool for the generation of small-compound libraries.
Archiv der Pharmazie 2006;339(9):489-97.
2006: Michael Saeftel; Ramadan Salem Sarite; Tujo Njuguna; Ulrike Holzgrabe; Daniela Ulmer; Achim Hoerauf; Annette Kaiser
Piperidones with activity against Plasmodium falciparum.
Parasitology research 2006;99(3):281-6.
2006: Ute Neugebauer; Ulrike Schmid; Knut Baumann; Ulrike Holzgrabe; Wilma Ziebuhr; Svetlana Kozitskaya; Wolfgang Kiefer; Michael Schmitt; Jürgen Popp
Characterization of bacterial growth and the influence of antibiotics by means of UV resonance Raman spectroscopy.
Biopolymers 2006;82(4):306-11.
2006: Ulrike Holzgrabe; Daniela Brinz; Susanne Kopec; Christine Weber; Yaser Bitar
Why not using capillary electrophoresis in drug analysis?
Electrophoresis 2006;27(12):2283-92.
2006: Roland Djang'eing'a Marini; Carl Groom; François R Doucet; Jalal Hawari; Yaser Bitar; Ulrike Holzgrabe; Roberto Gotti; Julie Schappler; Serge Rudaz; Jean-Luc Veuthey; Roelof Mol; Govert W Somsen; Gerhardus J De Jong; Pham Thi Thanh Ha; Jie Zhang; Ann Van Schepdael; Jos Hoogmartens; Willy Briône; Attilio Ceccato; Bruno Boulanger; Debby Mangelings; Yvan Vander Heyden; Willy Van Ael; Ilias Jimidar; Matteo Pedrini; Anne-Catherine Servais; Marianne Fillet; Jacques Crommen; Eric Rozet; Ph Hubert
Interlaboratory study of a NACE method for the determination of R-timolol content in S-timolol maleate: assessment of uncertainty.
Electrophoresis 2006;27(12):2386-99.
2006: Radim Vicik; Verena Hoerr; Melanie Glaser; Martina Schultheis; Elizabeth Hansell; James H McKerrow; Ulrike Holzgrabe; Conor R Caffrey; Alicia Ponte-Sucre; Heidrun Moll; August Stich; Tanja Schirmeister
Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents.
Bioorganic & medicinal chemistry letters 2006;16(10):2753-7.
2006: Ulf Sürig; Klaudia Gaal; Evi Kostenis; Christian Tränkle; Klaus Mohr; Ulrike Holzgrabe
Muscarinic allosteric modulators: atypical structure-activity-relationships in bispyridinium-type compounds.
Archiv der Pharmazie 2006;339(4):207-12.
2006: Andreas Heinze; Ulrike Holzgrabe
Determination of the extent of protein binding of antibiotics by means of an automated continuous ultrafiltration method.
International journal of pharmaceutics 2006;311(1-2):108-12.
2006: Petra Kapková; Vildan Alptüzün; Peter Frey; Ercin Erciyas; Ulrike Holzgrabe
Search for dual function inhibitors for Alzheimer's disease: synthesis and biological activity of acetylcholinesterase inhibitors of pyridinium-type and their Abeta fibril formation inhibition capacity.
Bioorganic & medicinal chemistry 2006;14(2):472-8.
2006: Teresa Disingrini; Mathias Muth; Clelia Dallanoce; Elisabetta Barocelli; Simona Bertoni; Kerstin Kellershohn; Klaus Mohr; Marco De Amici; Ulrike Holzgrabe
Design, synthesis, and action of oxotremorine-related hybrid-type allosteric modulators of muscarinic acetylcholine receptors.
Journal of medicinal chemistry 2006;49(1):366-72.
2006: Ulrike Holzgrabe; Marco De Amici; Klaus Mohr
Allosteric modulators and selective agonists of muscarinic receptors.
Journal of molecular neuroscience : MN 2006;30(1-2):165-8.
2006: Edith Bennack; Ulrike Holzgrabe
[A new weapon against beta-3 lactamases?].
Pharmazie in unserer Zeit 2006;35(5):387-8.
2006: Ulrike Holzgrabe
[Structure-activity relationships of penicillin G to tricyclic beta-lactams].
Pharmazie in unserer Zeit 2006;35(5):410-4.
2006: Ulrike Holzgrabe; Theo Dingermann; Ilse Zündorf
[An old pathway to new antibiotics--platensimycin].
Pharmazie in unserer Zeit 2006;35(5):388-9.
2006: Ulrike Holzgrabe
[Beta-lactam antibiotics as neuroprotectives].
Pharmazie in unserer Zeit 2006;35(5):387.
2006: Ulrike Holzgrabe; Edith Bennack
[Small change, large effect--a new vancomycin derivative against MRSA].
Pharmazie in unserer Zeit 2006;35(5):386.
2006: Ulrike Holzgrabe
[Perfect drug targeting. Glufosfamide a new derivative].
Pharmazie in unserer Zeit 2006;35(2):158-9.
2006: Ulrike Holzgrabe
[How does paracetamol work? A wider mosaic of action mechanisms].
Pharmazie in unserer Zeit 2006;35(2):100.
2006: Ulrike Holzgrabe
[Inhibition of virulence factors. A new approach to antibiotic development].
Pharmazie in unserer Zeit 2006;35(2):99.
2006: Ulrike Holzgrabe
[In Citation].
Pharmazie in unserer Zeit 2006;35(1):4.
2006: Maren Grossmüller; Johannes Antony; Christian Tränkle; Ulrike Holzgrabe; Klaus Mohr
Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist.
Naunyn-Schmiedeberg's archives of pharmacology 2006;372(4):267-76.
2005: Christian Tränkle; Andreas Dittmann; Uwe Schulz; Oliver Weyand; Stefan Buller; Kirstin Jöhren; Eberhard Heller; Nigel J M Birdsall; Ulrike Holzgrabe; John Ellis; Hans-Dieter Höltje; Klaus Mohr
Atypical muscarinic allosteric modulation: cooperativity between modulators and their atypical binding topology in muscarinic M2 and M2/M5 chimeric receptors.
Molecular pharmacology 2005;68(6):1597-610.
2005: Petra Kapková; Eberhard Heller; Matthias Unger; Gerd Folkers; Ulrike Holzgrabe
Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor.
Journal of medicinal chemistry 2005;48(23):7496-9.
2005: Yaser Bitar; Björn Degel; Tanja Schirmeister; Ulrike Holzgrabe
Comparison of the separation of aziridine isomers applying heptakis(2,3-di-O-methyl-6-sulfato)beta-CD and heptakis(2,3-di-O-acetyl-6-sulfato)beta-CD in aqueous and nonaqueous systems.
Electrophoresis 2005;26(20):3897-903.
2005: Werner Winter; Ralph Deubner; Ulrike Holzgrabe
Multivariate analysis of nuclear magnetic resonance data--characterization of critical drug substance quality of gentamicin sulfate.
Journal of pharmaceutical and biomedical analysis 2005;38(5):833-9.
2005: Ulrike Holzgrabe; R Deubner; C Schollmayer; B Waibel
Quantitative NMR spectroscopy--applications in drug analysis.
Journal of pharmaceutical and biomedical analysis 2005;38(5):806-12.
2005: C Weber; S Matingen; Ulrike Holzgrabe
Batch variability of bacitracin: HPLC versus MEKC.
Pharmeuropa scientific notes 2005;2005(1):47-51.
2005: Susanne Kopec; Ulrike Holzgrabe
Impurity profile of amino acids?
Pharmeuropa scientific notes 2005;2005(1):39-45.
2005: Matthias Unger; Stefanie Laug; Ulrike Holzgrabe
Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts.
Electrophoresis 2005;26(12):2430-6.
2005: Yaser Bitar; Björn Degel; Tanja Schirmeister; Ulrike Holzgrabe
Development and validation of a separation method for the diastereomers and enantiomers of aziridine-type protease inhibitors.
Electrophoresis 2005;26(12):2313-9.
2005: Wolfgang A Krueger; Jürgen Bulitta; Martina Kinzig; Cornelia Landersdorfer; Ulrike Holzgrabe; Kurt G Naber; George L Drusano; Fritz Sörgel
Evaluation by monte carlo simulation of the pharmacokinetics of two doses of meropenem administered intermittently or as a continuous infusion in healthy volunteers.
Antimicrobial agents and chemotherapy 2005;49(5):1881-9.
2005: Ute Neugebauer; Adriana Szeghalmi; Michael Schmitt; Wolfgang Kiefer; Jürgen Popp; Ulrike Holzgrabe
Vibrational spectroscopic characterization of fluoroquinolones.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2005;61(7):1505-17.
2005: Gerhard Bringmann; Inga Kajahn; Christian Neusüss; Matthias Pelzing; Stefanie Laug; Matthias Unger; Ulrike Holzgrabe
Analysis of the glucosinolate pattern of Arabidopsis thaliana seeds by capillary zone electrophoresis coupled to electrospray ionization-mass spectrometry.
Electrophoresis 2005;26(7-8):1513-22.
2005: Mathias Muth; Matthias Sennwitz; Klaus Mohr; Ulrike Holzgrabe
Muscarinic allosteric enhancers of ligand binding: pivotal pharmacophoric elements in hexamethonio-type agents.
Journal of medicinal chemistry 2005;48(6):2212-7.
2005: Christa Müller; Ulrike Holzgrabe
[Dear Colleagues].
Pharmazie in unserer Zeit 2005;34(6):443.
2005: Ulrike Holzgrabe
[New paths to highly effective tetracyclines].
Pharmazie in unserer Zeit 2005;34(4):258-9.
2005: Ulrike Holzgrabe
[Paclitaxel for Alzheimer treatment].
Pharmazie in unserer Zeit 2005;34(2):96.
2005: Ulrike Holzgrabe
[Artemisinin and successors].
Pharmazie in unserer Zeit 2005;34(2):95.
2005: Yulin Wang; Kang Tang; Saadet Inan; Daniel Siebert; Ulrike Holzgrabe; David Y W Lee; Peng Huang; Jian-Guo Li; Alan Cowan; Lee-Yuan Liu-Chen
Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo.
The Journal of pharmacology and experimental therapeutics 2005;312(1):220-30.
2004: Verena Hoerr; August Stich; Ulrike Holzgrabe
Critical aspects of analysis of Micrococcus luteus, Neisseria cinerea, and Pseudomonas fluorescens by means of capillary electrophoresis.
Electrophoresis 2004;25(18-19):3132-8.
2004: Claudia Kahle; Ulrike Holzgrabe
Determination of binding constants of cyclodextrin inclusion complexes with amino acids and dipeptides by potentiometric titration.
Chirality 2004;16(8):509-15.
2004: C Kirchhoff; Yaser Bitar; S Ebel; Ulrike Holzgrabe
Analysis of atropine, its degradation products and related substances of natural origin by means of reversed-phase high-performance liquid chromatography.
Journal of chromatography. A 2004;1046(1-2):115-20.
2004: Ulrich Schmitt; Mevlut Ertan; Ulrike Holzgrabe
Chiral capillary electrophoresis: facts and fiction on the reproducibility of resolution with randomly substituted cyclodextrins.
Electrophoresis 2004;25(16):2801-7.
2004: Marion Mohr; Eberhard Heller; Ameneh Ataie; Klaus Mohr; Ulrike Holzgrabe
Development of a new type of allosteric modulator of muscarinic receptors: hybrids of the antagonist AF-DX 384 and the hexamethonio derivative W84.
Journal of medicinal chemistry 2004;47(12):3324-7.
2004: Ralph Deubner; Ulrike Holzgrabe
Micellar electrokinetic capillary chromatography, high performance liquid chromatography and nuclear magnetic resonance--three orthogonal methods for characterization of critical drugs.
Journal of pharmaceutical and biomedical analysis 2004;35(3):459-67.
2004: Ulrike Holzgrabe
[Selective estrogen receptor modulators].
Pharmazie in unserer Zeit 2004;33(5):357-9.
2004: Ulrike Holzgrabe
[Flexibility in avoiding resistance].
Pharmazie in unserer Zeit 2004;33(5):349.
2004: Ulrike Holzgrabe
[A fungal substance against arteriosclerosis].
Pharmazie in unserer Zeit 2004;33(5):348-9.
2004: Ulrike Holzgrabe
[A riddle solved--why valerian-hops extract makes you drowsy].
Pharmazie in unserer Zeit 2004;33(5):348.
2004: Ulrike Holzgrabe
[A new in star in antibiotic heaven--daptomycin].
Pharmazie in unserer Zeit 2004;33(4):270.
2004: Ulrike Holzgrabe
[Protease inhibitors against hepatitis C].
Pharmazie in unserer Zeit 2004;33(3):160-1.
2004: Ulrike Holzgrabe
[HIV therapy: and an even newer treatment--PA-457].
Pharmazie in unserer Zeit 2004;33(3):160.
2004: Matthias Unger; Michael Dreyer; Sven Specker; Stefanie Laug; Matthias Pelzing; Christian Neusüss; Ulrike Holzgrabe; Gerhard Bringmann
Analytical characterisation of crude extracts from an African Ancistrocladus species using high-performance liquid chromatography and capillary electrophoresis coupled to ion trap mass spectrometry.
Phytochemical analysis : PCA 2004;15(1):21-6.
2004: Ulrike Holzgrabe
[And the path grows wider...ketolides and oxazolidinones in the pipeline].
Pharmazie in unserer Zeit 2004;33(1):56-7.
2004: Ulrike Holzgrabe
[New treatments against AIDS: fusion inhibitors].
Pharmazie in unserer Zeit 2004;33(1):6.
2003: Petra Kapková; Nikolaus Stiefl; Ulf Sürig; Bernd Engels; Knut Baumann; Ulrike Holzgrabe
Synthesis, biological activity, and docking studies of new acetylcholinesterase inhibitors of the bispyridinium type.
Archiv der Pharmazie 2003;336(11):523-40.
2003: Vildan Alptüzün; Petra Kapková; Knut Baumann; Ercin Erciyas; Ulrike Holzgrabe
Synthesis and biological activity of pyridinium-type acetylcholinesterase inhibitors.
The Journal of pharmacy and pharmacology 2003;55(10):1397-404.
2003: Frank Wienen; Ulrike Holzgrabe
A new micellar electrokinetic capillary chromatography method for separation of the components of the aminoglycoside antibiotics.
Electrophoresis 2003;24(17):2948-57.
2003: Markus Staudt; Christian Tränkle; Klaus Mohr; Ulrike Holzgrabe
Contribution of lateral substituents in symmetrical and non-symmetrical heptane-bisammonio compounds to the allosteric stabilization of N-methylscopolamine binding to muscarinic M2 receptors.
Archiv der Pharmazie 2003;336(8):385-9.
2003: Bilal Awadallah; Peter C Schmidt; Ulrike Holzgrabe; Martin A Wahl
Quantitation of talinolol and other beta-blockers by capillary electrophoresis for in vitro drug absorption studies.
Electrophoresis 2003;24(15):2627-32.
2003: Thomas Raab; Tobias Hauck; Anja Knecht; Ulrich Schmitt; Ulrike Holzgrabe; Wilfried Schwab
Tautomerism of 4-hydroxy-2,5-dimethyl-3(2H)-furanone: evidence for its enantioselective biosynthesis.
Chirality 2003;15(7):573-8.
2003: Darius P Zlotos; Stefan Buller; Ulrike Holzgrabe; Klaus Mohr
Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors.
Bioorganic & medicinal chemistry 2003;11(12):2627-34.
2003: G Bringmann; Verena Hoerr; Ulrike Holzgrabe; August Stich
Antitrypanosomal naphthylisoquinoline alkaloids and related compounds.
Die Pharmazie 2003;58(5):343-6.
2003: Ulrike Holzgrabe; Wolfgang Brandt
Mechanism of action of the diazabicyclononanone-type kappa-agonists.
Journal of medicinal chemistry 2003;46(8):1383-9.
2003: Ralf Gilsbach; Maren Grossmüller; Vildan Alptüzün; Ercin Erciyas; Christian Tränkle; Ulrike Holzgrabe; Klaus Mohr
Cooperative interactions at M2 muscarinic acetylcholine receptors: structure/activity relationships in stepwise shortened bispyridinium- and bis(ammonio)alkane-type allosteric modulators.
Neurochemical research 2003;28(3-4):667-73.
2003: Mathias Muth; Wiebke Bender; Olaf Scharfenstein; Ulrike Holzgrabe; Edith Balatkova; Christian Tränkle; Klaus Mohr
Systematic development of high affinity bis(ammonio)alkane-type allosteric enhancers of muscarinic ligand binding.
Journal of medicinal chemistry 2003;46(6):1031-40.
2003: Frank Wienen; Stefanie Laug; Knut Baumann; Albrecht Schwab; Stefan Just; Ulrike Holzgrabe
Determination of clotrimazole in mice plasma by capillary electrophoresis.
Journal of pharmaceutical and biomedical analysis 2003;30(6):1879-87.
2003: Sándor Benyhe; Arpád Márki; Corina Nachtsheim; Ulrike Holzgrabe; Anna Borsodi
Kappa-receptor selective binding of opioid ligands with a heterocyclic bicyclo[3.3.1]nonan-9-one structure.
Acta biologica Hungarica 2003;54(2):147-55.
2003: Klaus Mohr; Christian Tränkle; Ulrike Holzgrabe
Structure/activity relationships of M2 muscarinic allosteric modulators.
Receptors & channels 2003;9(4):229-40.
2003: Monika Schäfer-Korting; Ulrike Holzgrabe
[A silver lining on the horizon: new antimycotics].
Pharmazie in unserer Zeit 2003;32(2):154-6.
2003: Ulrike Holzgrabe
[Arrays overall].
Pharmazie in unserer Zeit 2003;32(2):91-2.
2003: Ulrike Holzgrabe; Monika Schäfer-Korting
[Antimycotics].
Pharmazie in unserer Zeit 2003;32(2):87.
2002: Matthias Unger; Ulrike Holzgrabe; Wolfgang Jacobsen; Carolyn Cummins; Leslie Z Benet
Inhibition of cytochrome P450 3A4 by extracts and kavalactones of Piper methysticum (Kava-Kava).
Planta medica 2002;68(12):1055-8.
2002: Alexandra Raasch; Olaf Scharfenstein; Christian Tränkle; Ulrike Holzgrabe; Klaus Mohr
Elevation of ligand binding to muscarinic M(2) acetylcholine receptors by bis(ammonio)alkane-type allosteric modulators.
Journal of medicinal chemistry 2002;45(17):3809-12.
2002: Ulrike Holzgrabe; A Cambareri; U Kuhl; T Siener; W Brandt; Wolfgang Strassburger; Elmar Friderichs; Werner Englberger; Babette Kögel; Michael Haurand
Diazabicyclononanones, a potent class of kappa opioid analgesics.
Farmaco (Società chimica italiana : 1989) 2002;57(7):531-4.
2002: Barbara Heller; Bernd Sundermann; Helmut Buschmann; Hans-Joachim Drexler; Jingsong You; Ulrike Holzgrabe; Eberhard Heller; Günther Oehme
Photocatalyzed [2 + 2 + 2]-cycloaddition of nitriles with acetylene: an effective method for the synthesis of 2-pyridines under mild conditions.
The Journal of organic chemistry 2002;67(13):4414-22.
2002: Maike Wedig; Nikolai Novatchev; Tina Worch; Stefanie Laug; Ulrike Holzgrabe
Evaluation of the impurity profile of alcuronium by means of capillary electrophoresis.
Journal of pharmaceutical and biomedical analysis 2002;28(5):983-90.
2002: Nikolai Novatchev; Ulrike Holzgrabe
Evaluation of amino sugar, low molecular peptide and amino acid impurities of biotechnologically produced amino acids by means of CE.
Journal of pharmaceutical and biomedical analysis 2002;28(3-4):475-86.
2002: Falko Süss; Claudia Kahle; Ulrike Holzgrabe; Gerhard K E Scriba
Studies on the chiral recognition of peptide enantiomers by neutral and sulfated beta-cyclodextrin and heptakis-(2,3-di-O-acetyl)-beta-cyclodextrin using capillary electrophoresis and nuclear magnetic resonance.
Electrophoresis 2002;23(9):1301-7.
2002: Matthias Unger; Wolfgang Jacobsen; Ulrike Holzgrabe; Leslie Z Benet
Quantitative liquid chromatography-mass spectrometry determination of isatin in urine using automated on-line extraction.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;767(2):245-53.
2002: Maike Wedig; Stefanie Laug; T Christians; M Thunhorst; Ulrike Holzgrabe
Do we know the mechanism of chiral recognition between cyclodextrins and analytes?
Journal of pharmaceutical and biomedical analysis 2002;27(3-4):531-40.
2002: Ulrike Holzgrabe
[Ibuprofen for Alzheimer's?].
Pharmazie in unserer Zeit 2002;31(2):130.
2002: Ulrike Holzgrabe; Thorsten Christians
The use of cyclodextrin-modified capillary electrophoresis in the determination of the enantiomeric purity.
Journal of capillary electrophoresis and microchip technology 2002;7(1-2):23-9.
2001: Nikolai Novatchev; Ulrike Holzgrabe
Evaluation of the impurity profile of amino acids by means of CE.
Journal of pharmaceutical and biomedical analysis 2001;26(5-6):779-89.
2001: Ulrike Holzgrabe; M Steinert
N1-phenyl substituted 4-quinolones of tuberculostatic activity.
Die Pharmazie 2001;56(11):850-1.
2001: Maike Wedig; M Thunhorst; Stefanie Laug; M Decker; J Lehmann; Ulrike Holzgrabe
Enantioseparation of linear and cyclic chiral bis(phenethyl)amines by means of cyclodextrin-modified capillary electrophoresis.
Fresenius' journal of analytical chemistry 2001;371(2):212-7.
2001: Ulrich Schmitt; J Bojarski; Ulrike Holzgrabe
Enantioseparation of chiral thiobarbiturates using cyclodextrin-modified capillary electrophoresis.
Electrophoresis 2001;22(15):3237-42.
2001: Christine Hellriegel; Heidi Händel; Maike Wedig; S Steinhauer; F Sörgel; Klaus Albert; Ulrike Holzgrabe
Study on the chiral recognition of the enantiomers of ephedrine derivatives with neutral and sulfated heptakis(2,3-O-diacetyl)-beta-cyclodextrins using capillary electrophoresis, UV, nuclear magnetic resonance spectroscopy and mass spectrometry.
Journal of chromatography. A 2001;914(1-2):315-24.
2001: T Christians; Ulrike Holzgrabe
New single-isomer chiral selector for capillary electrophoresis: the highly water-soluble heptakis(2-N,N-dimethylcarbamoyl)-beta-cyclodextrin.
Journal of chromatography. A 2001;911(2):249-57.
2001: Ulrike Holzgrabe
[Where are quinolones going? New agents in development].
Pharmazie in unserer Zeit 2001;30(5):446-8.
2000: T Christians; Ulrike Holzgrabe
Enantioseparation of dihydropyridine derivatives by means of neutral and negatively charged beta-cyclodextrin derivatives using capillary electrophoresis.
Electrophoresis 2000;21(17):3609-17.
2000: T Siener; A Cambareri; U Kuhl; Werner Englberger; Michael Haurand; Babette Kögel; Ulrike Holzgrabe
Synthesis and opioid receptor affinity of a series of 2, 4-diaryl-substituted 3,7-diazabicylononanones.
Journal of medicinal chemistry 2000;43(20):3746-51.
2000: U Kuhl; Werner Englberger; Michael Haurand; Ulrike Holzgrabe
Diazabicyclo[3.3.1]nonanone-type ligands for the opioid receptors.
Archiv der Pharmazie 2000;333(7):226-30.
2000: H M Botero Cid; Christian Tränkle; Knut Baumann; R Pick; E Mies-Klomfass; Evi Kostenis; Klaus Mohr; Ulrike Holzgrabe
Structure-activity relationships in a series of bisquaternary bisphthalimidine derivatives modulating the muscarinic M(2)-receptor allosterically.
Journal of medicinal chemistry 2000;43(11):2155-64.
2000: Wiebke Bender; Markus Staudt; Christian Tränkle; Klaus Mohr; Ulrike Holzgrabe
Probing the size of a hydrophobic binding pocket within the allosteric site of muscarinic acetylcholine M2-receptors.
Life sciences 2000;66(18):1675-82.
2000: Ulrike Holzgrabe; Wiebke Bender; H M Cid; Markus Staudt; R Pick; C Pfletschinger; E Balatková; Christian Tränkle; Klaus Mohr
Ligands for the common allosteric site of acetylcholine M2-receptors: development and application.
Pharmaceutica acta Helvetiae 2000;74(2-3):149-55.
1999: Maike Wedig; Ulrike Holzgrabe
Resolution of ephedrine derivatives by means of neutral and sulfated heptakis(2,3-di-O-acetyl)beta-cyclodextrins using capillary electrophoresis and nuclear magnetic resonance spectroscopy.
Electrophoresis 1999;20(13):2698-704.
1999: T Christians; D Diewald; C Wessler; Y Otte; Jochen Lehmann; Ulrike Holzgrabe
Resolution of newly synthesized racemic dihydropyridines with different chiral selectors by means of capillary electrophoresis.
Journal of chromatography. A 1999;853(1-2):455-60.
1999: E Inkmann; Ulrike Holzgrabe
1H and 13C nuclear magnetic resonance studies of the sites of protonation in itraconazole and fluconazole.
Journal of pharmaceutical and biomedical analysis 1999;20(1-2):297-307.
1999: M Wedig; Ulrike Holzgrabe
Enantioseparation of tropa alkaloids by means of anionic cyclodextrin-modified capillary electrophoresis.
Electrophoresis 1999;20(7):1555-60.
1999: T Nassif-Makki; Christian Tränkle; Darius P Zlotos; G Bejeuhr; A Cambareri; C Pfletschinger; Evi Kostenis; Klaus Mohr; Ulrike Holzgrabe
Bisquaternary ligands of the common allosteric site of M2 acetylcholine receptors: search for the minimum essential distances between the pharmacophoric elements.
Journal of medicinal chemistry 1999;42(5):849-58.
1999: Ulrike Holzgrabe; P Heisig
[New 4-quinolone derivatives in review].
Pharmazie in unserer Zeit 1999;28(1):30-5.
1998: G Zlotos; M Oehlmann; Peter Nickel; Ulrike Holzgrabe
Determination of protein binding of gyrase inhibitors by means of continuous ultrafiltration.
Journal of pharmaceutical and biomedical analysis 1998;18(4-5):847-58.
1998: Ulrike Holzgrabe; B W Diehl; I Wawer
NMR spectroscopy in pharmacy.
Journal of pharmaceutical and biomedical analysis 1998;17(4-5):557-616.
1998: Christian Tränkle; E Mies-Klomfass; M H Cid; Ulrike Holzgrabe; Klaus Mohr
Identification of a [3H]Ligand for the common allosteric site of muscarinic acetylcholine M2 receptors.
Molecular pharmacology 1998;54(1):139-45.
1998: M Engler; G Rüsing; Fritz Sörgel; Ulrike Holzgrabe
Defluorinated sparfloxacin as a new photoproduct identified by liquid chromatography coupled with UV detection and tandem mass spectrometry.
Antimicrobial agents and chemotherapy 1998;42(5):1151-9.
1998: G Zlotos; A Bücker; Martina Kinzig; F Sorgel; Ulrike Holzgrabe
Plasma protein binding of gyrase inhibitors.
Journal of pharmaceutical sciences 1998;87(2):215-20.
1998: Markus Staudt; Christian Tränkle; Klaus Mohr; Ulrike Holzgrabe
Contribution of lateral substituents in heptane-bisammonium derivatives to the allosteric stabilization of antagonist binding to M2-receptors.
Life sciences 1998;62(5):423-9.
1997: E Inkmann; Ulrike Holzgrabe; K F Hesse
Stability of mono- and bisbenzyloxime ethers of the acetylcholinesterase reactivator TMB-4.
Die Pharmazie 1997;52(10):764-74.
1997: Ulrike Holzgrabe
[New antiepileptics in review].
Pharmazie in unserer Zeit 1997;26(3):152-6.
1997: Ulrike Holzgrabe; C Nachtsheim; T Siener; S Drosihn; W Brandt
[Opioid agonists and antagonists, opioid receptors].
Die Pharmazie 1997;52(1):4-22.
1996: Ulrike Holzgrabe; A J Hopfinger
Conformational analysis, molecular shape comparison, and pharmacophore identification of different allosteric modulators of muscarinic receptors.
Journal of chemical information and computer sciences 1996;36(5):1018-24.
1996: Ulrike Holzgrabe; M Wagener; Johann Gasteiger
Comparison of structurally different allosteric modulators of muscarinic receptors by self-organizing neural networks.
Journal of molecular graphics 1996;14(4):185-93, 217-21.
1996: W Brandt; S Drosihn; M Haurand; Ulrike Holzgrabe; C Nachtsheim
Search for the pharmacophore in kappa-agonistic diazabicyclo[3.3.1]nonan-9-one-1,5-diesters and arylacetamides.
Archiv der Pharmazie 1996;329(6):311-23.
1996: J Jürgens; H Schedletzky; P Heisig; J K Seydel; Bernd Wiedemann; Ulrike Holzgrabe
Syntheses and biological activities of new N1-aryl substituted quinolone antibacterials.
Archiv der Pharmazie 1996;329(4):179-90.
1995: Johann Gasteiger; Ulrike Holzgrabe; E Kostenis; Klaus Mohr; U Sürig; M Wagener
Variation of the oxime function of bispyridinium-type allosteric modulators of M2-cholinoceptors.
Die Pharmazie 1995;50(2):99-105.
1994: Ulrike Holzgrabe
[Anatoxin-a: a bacterial organophosphate].
Pharmazie in unserer Zeit 1994;23(5):301-2.
1994: M H Botero Cid; Ulrike Holzgrabe; E Kostenis; Klaus Mohr; Christian Tränkle
Search for the pharmacophore of bispyridinium-type allosteric modulators of muscarinic receptors.
Journal of medicinal chemistry 1994;37(10):1439-45.
1994: G Bejeuhr; G Blaschke; Ulrike Holzgrabe; Klaus Mohr; U Sürig; G Terfloth
A stable and highly potent hexamethonium derivative which modulates muscarinic receptors allosterically in guinea-pig hearts.
The Journal of pharmacy and pharmacology 1994;46(2):108-12.
1992: Ulrike Holzgrabe; E Erciyas
[Synthesis and stereochemistry of potentially powerful analgesics: 2,4-m-diaryl substituted 3,7-diazabicyclo(3,3,1)nonan-9-one-1,5-diesters].
Archiv der Pharmazie 1992;325(10):657-63.
1990: Ulrike Holzgrabe; G Bejeuhr
[Phosphoric acid esters: poisoning and therapy at the molecular sight].
Pharmazie in unserer Zeit 1990;19(6):247-56.