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Bernhard Holzmann

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Gabriela Jusek; Daniel Reim; Kazutake Tsujikawa; Bernhard Holzmann
Deficiency of the CGRP receptor component RAMP1 attenuates immunosuppression during the early phase of septic peritonitis.
Petra Gais; Felicitas Altmayr; Klaus-Peter Janssen; Gabriela Jusek; Klaus Pfeffer; Daniel Reim; Tanja Rossmann-Bloeck; Heike Weighardt; Bernhard Holzmann
Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis.
Alexander R Novotny; Daniel Reim; Felicitas Altmayr; Volker Assfalg; Klaus Emmanuel; Helmut M Friess; Bernhard Holzmann
Mixed antagonist response and sepsis severity-dependent dysbalance of pro- and anti-inflammatory responses at the onset of postoperative sepsis.

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2012: Gabriela Jusek; Daniel Reim; Kazutake Tsujikawa; Bernhard Holzmann
Deficiency of the CGRP receptor component RAMP1 attenuates immunosuppression during the early phase of septic peritonitis.
Immunobiology 2012;217(8):761-7.
2012: Petra Gais; Felicitas Altmayr; Klaus-Peter Janssen; Gabriela Jusek; Klaus Pfeffer; Daniel Reim; Tanja Rossmann-Bloeck; Heike Weighardt; Bernhard Holzmann
Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(12):5833-7.
2012: Alexander R Novotny; Daniel Reim; Felicitas Altmayr; Volker Assfalg; Klaus Emmanuel; Helmut M Friess; Bernhard Holzmann
Mixed antagonist response and sepsis severity-dependent dysbalance of pro- and anti-inflammatory responses at the onset of postoperative sepsis.
Immunobiology 2012;217(6):616-21.
2011: Melanie Martini; Daniela Scheikl; Alexandra Gnann; Bernhard Holzmann; Klaus-Peter Janssen
The candidate tumor suppressor SASH1 interacts with the actin cytoskeleton and stimulates cell-matrix adhesion.
The international journal of biochemistry & cell biology 2011;43(11):1630-40.
2011: Daniel Reim; Tanja Rossmann-Bloeck; Gabriela Jusek; Olivia Prazeres da Costa; Bernhard Holzmann
Improved host defense against septic peritonitis in mice lacking MyD88 and TRIF is linked to a normal interferon response.
Journal of leukocyte biology 2011;90(3):613-20.
2010: Matthias C Schauer; Bernhard Holzmann; Matthias Peiper; Helmut Friess; Wolfram Trudo Knoefel; Jörg Theisen
Interleukin-10 and -12 predict chemotherapy-associated toxicity in esophageal adenocarcinoma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010;5(11):1849-54.
2010: Michael Hammer; Bernd Echtenachter; Heike Weighardt; Katrin Jozefowski; Stefan Rose-John; Daniela N Männel; Bernhard Holzmann; Roland Lang
Increased inflammation and lethality of Dusp1-/- mice in polymicrobial peritonitis models.
Immunology 2010;131(3):395-404.
2010: Petra Gais; Christopher Tiedje; Felicitas Altmayr; Matthias Gaestel; Heike Weighardt; Bernhard Holzmann
TRIF signaling stimulates translation of TNF-alpha mRNA via prolonged activation of MK2.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(10):5842-8.
2010: dietrich doll; Larissa Keller; Matthias Maak; Anne-Laure Boulesteix; Jörg R Siewert; Bernhard Holzmann; Klaus-Peter Janssen
Differential expression of the chemokines GRO-2, GRO-3, and interleukin-8 in colon cancer and their impact on metastatic disease and survival.
International journal of colorectal disease 2010;25(5):573-81.
2010: Felicitas Altmayr; Gabriela Jusek; Bernhard Holzmann
The neuropeptide calcitonin gene-related peptide causes repression of tumor necrosis factor-alpha transcription and suppression of ATF-2 promoter recruitment in Toll-like receptor-stimulated dendritic cells.
The Journal of biological chemistry 2010;285(6):3525-31.
2010: Volker Assfalg; Norbert Hüser; Daniel Reim; Simone Kaiser-Moore; Tanja Rossmann-Bloeck; Heike Weighardt; Alexander R Novotny; Manfred Stangl; Bernhard Holzmann; Klaus L Emmanuel
Combined immunosuppressive and antibiotic therapy improves bacterial clearance and survival of polymicrobial septic peritonitis.
Shock (Augusta, Ga.) 2010;33(2):155-61.
2010: Norbert Hüser; Annette Fasan; Monika Semmrich; Patricia Schmidbauer; Bernhard Holzmann; Melanie Laschinger
Intact LFA-1 deactivation promotes T-cell activation and rejection of cardiac allograft.
International immunology 2010;22(1):35-44.
2009: Norbert Hüser; Edouard Matevossian; Patricia Schmidbauer; Volker Assfalg; Juergen E Scherberich; Manfred Stangl; Bernhard Holzmann; Helmut Friess; Melanie Laschinger
Calculated withdrawal of low-dose immunosuppression based on a detailed immunological monitoring after kidney transplantation between monocygotic twins.
Transplant immunology 2009;22(1-2):38-43.
2009: Daniel Reim; Kay Westenfelder; Simone Kaiser-Moore; Sylvia Schlautkötter; Bernhard Holzmann; Heike Weighardt
Role of T cells for cytokine production and outcome in a model of acute septic peritonitis.
Shock (Augusta, Ga.) 2009;31(3):245-50.
2008: A Anjomshoaa; Y-H Lin; M A Black; John L McCall; Bostjan Humar; S Song; Ryuji Fukuzawa; H-S Yoon; Bernhard Holzmann; Jan Friederichs; Andre M Van Rij; Mark W Thompson-Fawcett; Anthony E Reeve
Reduced expression of a gene proliferation signature is associated with enhanced malignancy in colon cancer.
British journal of cancer 2008;99(6):966-73.
2008: Xaver Sewald; Bettina Gebert-Vogl; Sandra Prassl; Iris Barwig; Evelyn Weiss; Monica Fabbri; Radim Osicka; Matthias Schiemann; Dirk H Busch; Monika Semmrich; Bernhard Holzmann; Peter Sebo; Rainer Haas
Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin.
Cell host & microbe 2008;3(1):20-9.
2007: Jan Friederichs; Ralf Gertler; Robert Rosenberg; Michael Dahm; Hjalmar Nekarda; Bernhard Holzmann; Jörg Rüdiger Siewert
Correlation of CK-20-positive cells in peripheral venous blood with serum CEA levels in patients with colorectal carcinoma.
World journal of surgery 2007;31(12):2329-34.
2007: Franziska Rohde; Caroline Rimkus; Jan Friederichs; Robert Rosenberg; Carmen Marthen; dietrich doll; Bernhard Holzmann; Jörg Rüdiger Siewert; Klaus-Peter Janssen
Expression of osteopontin, a target gene of de-regulated Wnt signaling, predicts survival in colon cancer.
International journal of cancer. Journal international du cancer 2007;121(8):1717-23.
2007: Marit D Harzenetter; Alexander R Novotny; Petra Gais; Carlos A Molina; Felicitas Altmayr; Bernhard Holzmann
Negative regulation of TLR responses by the neuropeptide CGRP is mediated by the transcriptional repressor ICER.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(1):607-15.
2007: Alexander R Novotny; Klaus Emmanuel; Edouard Matevossian; Monika Kriner; Kurt Ulm; Holger Bartels; Bernhard Holzmann; Heike Weighardt; Jörg Rüdiger Siewert
Use of procalcitonin for early prediction of lethal outcome of postoperative sepsis.
American journal of surgery 2007;194(1):35-9.
2007: Georg F Weber; Sylvia Schlautkötter; Simone Kaiser-Moore; Felicitas Altmayr; Bernhard Holzmann; Heike Weighardt
Inhibition of interleukin-22 attenuates bacterial load and organ failure during acute polymicrobial sepsis.
Infection and immunity 2007;75(4):1690-7.
2007: Tatjana Dorn; Ursula Kuhn; Gerd Bungartz; Sebastian Stiller; Martina Bauer; Joachim W Ellwart; Thorsten Peters; Karin Scharffetter-Kochanek; Monika Semmrich; Melanie Laschinger; Bernhard Holzmann; Wolfgang E F Klinkert; Per thor Straten; Tania Køllgaard; Michael Sixt; Cord Brakebusch
RhoH is important for positive thymocyte selection and T-cell receptor signaling.
Blood 2007;109(6):2346-55.
2007: Alexander R Novotny; Klaus Emmanuel; Stefan Maier; Alexandra Westerholt; Heike Weighardt; Josef Stadler; Holger Bartels; Markus Schwaiger; Jörg Rüdiger Siewert; Bernhard Holzmann; Claus-Dieter Heidecke
Cytochrome P450 activity mirrors nitric oxide levels in postoperative sepsis: predictive indicators of lethal outcome.
Surgery 2007;141(3):376-84.
2007: Yu-Hsin Lin; Jan Friederichs; Michael A Black; Jörg Mages; Robert Rosenberg; Parry Guilford; Vicky Phillips; Mark Thompson-Fawcett; Nikola Kasabov; Tumi Toro; Arend E H Merrie; Andre M Van Rij; Han-Seung Yoon; John L McCall; Jörg Rüdiger Siewert; Bernhard Holzmann; Anthony E Reeve
Multiple gene expression classifiers from different array platforms predict poor prognosis of colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(2 Pt 1):498-507.
2007: Heike Weighardt; Bernhard Holzmann
Role of Toll-like receptor responses for sepsis pathogenesis.
Immunobiology 2007;212(9-10):715-22.
2007: Caroline Rimkus; Jan Friederichs; Robert Rosenberg; Bernhard Holzmann; Jörg Rüdiger Siewert; Klaus-Peter Janssen
Expression of the mitotic checkpoint gene MAD2L2 has prognostic significance in colon cancer.
International journal of cancer. Journal international du cancer 2007;120(1):207-11.
2006: Georg F Weber; Florian C Gaertner; Wolfgang Erl; Klaus-Peter Janssen; Birgit Blechert; Bernhard Holzmann; Heike Weighardt; Markus Essler
IL-22-mediated tumor growth reduction correlates with inhibition of ERK1/2 and AKT phosphorylation and induction of cell cycle arrest in the G2-M phase.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(11):8266-72.
2006: Caroline Rimkus; M Martini; Jan Friederichs; Robert Rosenberg; dietrich doll; Jörg Rüdiger Siewert; Bernhard Holzmann; Klaus-Peter Janssen
Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancer.
British journal of cancer 2006;95(10):1419-23.
2006: Heike Weighardt; Simone Kaiser-Moore; Sylvia Schlautkötter; Tanja Rossmann-Bloeck; Ulrike Schleicher; Christian Bogdan; Bernhard Holzmann
Type I IFN modulates host defense and late hyperinflammation in septic peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5623-30.
2006: Alexander R Novotny; Klaus Emmanuel; Kurt Ulm; Holger Bartels; Jörg Rüdiger Siewert; Heike Weighardt; Bernhard Holzmann
Blood interleukin 12 as preoperative predictor of fatal postoperative sepsis after neoadjuvant radiochemotherapy.
The British journal of surgery 2006;93(10):1283-9.
2006: Heike Weighardt; Jörg Mages; Gabriela Jusek; Simone Kaiser-Moore; Roland Lang; Bernhard Holzmann
Organ-specific role of MyD88 for gene regulation during polymicrobial peritonitis.
Infection and immunity 2006;74(6):3618-32.
2006: Markus Entleutner; Tobias Traeger; Alexandra Westerholt; Bernhard Holzmann; Albrecht Stier; Klaus Pfeffer; Stefan Maier; Claus-Dieter Heidecke
Impact of interleukin-12, oxidative burst, and iNOS on the survival of murine fecal peritonitis.
International journal of colorectal disease 2006;21(1):64-70.
2005: Sandra Beer; Tanja Scheikl; Bernhard Reis; Norbert Hüser; Klaus Pfeffer; Bernhard Holzmann
Impaired immune responses and prolonged allograft survival in Sly1 mutant mice.
Molecular and cellular biology 2005;25(21):9646-60.
2005: Alexander R Novotny; Klaus Emmanuel; Holger Bartels; Jörg Rüdiger Siewert; Bernhard Holzmann
[Indicators for early prediction of outcome in sepsis].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2005;76(9):837-44.
2005: Jan Friederichs; Robert Rosenberg; Joerg Mages; Klaus-Peter Janssen; Christian Maeckl; Hjalmar Nekarda; Bernhard Holzmann; Joerg-Ruediger Siewert
Gene expression profiles of different clinical stages of colorectal carcinoma: toward a molecular genetic understanding of tumor progression.
International journal of colorectal disease 2005;20(5):391-402.
2005: Carolin Feterowski; Alexander R Novotny; Simone Kaiser-Moore; Peter F Mühlradt; Tanja Rossmann-Bloeck; Martina Rump; Bernhard Holzmann; Heike Weighardt
Attenuated pathogenesis of polymicrobial peritonitis in mice after TLR2 agonist pre-treatment involves ST2 up-regulation.
International immunology 2005;17(8):1035-46.
2005: Monika Semmrich; Andrew Smith; Carolin Feterowski; Sandra Beer; Britta Engelhardt; Dirk H Busch; Bernadett Bartsch; Melanie Laschinger; Nancy Hogg; Klaus Pfeffer; Bernhard Holzmann
Importance of integrin LFA-1 deactivation for the generation of immune responses.
The Journal of experimental medicine 2005;201(12):1987-98.
2005: Jan Friederichs; Ralf Gertler; Robert Rosenberg; Jörg Nahrig; Katrin Führer; Bernhard Holzmann; Hans-Joachim Dittler; Michael Dahm; Stefan Thorban; Hjalmar Nekarda; Jörg Rüdiger Siewert
Prognostic impact of CK-20-positive cells in peripheral venous blood of patients with gastrointestinal carcinoma.
World journal of surgery 2005;29(4):422-8.
2005: Klaus Emmanuel; Heike Weighardt; Holger Bartels; Jorg-Rudiger Siewert; Bernhard Holzmann
Current and future concepts of abdominal sepsis.
World journal of surgery 2005;29(1):3-9.
2004: Carolin Feterowski; Matthias Mack; Heike Weighardt; Bernadett Bartsch; Simone Kaiser-Moore; Bernhard Holzmann
CC chemokine receptor 2 regulates leukocyte recruitment and IL-10 production during acute polymicrobial sepsis.
European journal of immunology 2004;34(12):3664-73.
2004: Klaus Ruckdeschel; Gudrun Pfaffinger; Rudolf Haase; Andreas Sing; Heike Weighardt; Georg Häcker; Bernhard Holzmann; Jürgen Heesemann
Signaling of apoptosis through TLRs critically involves toll/IL-1 receptor domain-containing adapter inducing IFN-beta, but not MyD88, in bacteria-infected murine macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):3320-8.
2004: Stefan Maier; Tobias Traeger; Markus Entleutner; Alexandra Westerholt; Britta Kleist; Norbert Hüser; Bernhard Holzmann; Albrecht Stier; Klaus Pfeffer; Claus-Dieter Heidecke
Cecal ligation and puncture versus colon ascendens stent peritonitis: two distinct animal models for polymicrobial sepsis.
Shock (Augusta, Ga.) 2004;21(6):505-11.
2004: Ralf Gertler; Robert Rosenberg; Dominik Stricker; Jan Friederichs; Axel Hoos; Martin Werner; Kurt Ulm; Bernhard Holzmann; Hjalmar Nekarda; Joerg-Ruediger Siewert
Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(10):1807-14.
2004: Heike Weighardt; Gabriela Jusek; Jörg Mages; Roland Lang; Kasper Hoebe; Bruce Beutler; Bernhard Holzmann
Identification of a TLR4- and TRIF-dependent activation program of dendritic cells.
European journal of immunology 2004;34(2):558-64.
2003: Elsa Locardi; Jürgen Boer; Armin Modlinger; Anja Schuster; Bernhard Holzmann; Horst Kessler
Synthesis and structure-activity relationship of mannose-based peptidomimetics selectively blocking integrin alpha4beta7 binding to mucosal addressin cell adhesion molecule-1.
Journal of medicinal chemistry 2003;46(26):5752-62.
2003: Carolin Feterowski; Klaus Emmanuilidis; Thomas Miethke; Klaus Gerauer; Martina Rump; Kurt Ulm; Bernhard Holzmann; Heike Weighardt
Effects of functional Toll-like receptor-4 mutations on the immune response to human and experimental sepsis.
Immunology 2003;109(3):426-31.
2003: Bernhard Holzmann; Heike Weighardt; Claus-Dieter Heidecke
[Receptors and signal proteins of the innate immune system as new targets in sepsis therapy. Reprogramming of the immune response].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2003;74(1):61-4.
2002: Klaus Emmanuilidis; Heike Weighardt; Edouard Matevossian; Claus-Dieter Heidecke; Kurt Ulm; Holger Bartels; Jörg Rüdiger Siewert; Bernhard Holzmann
Differential regulation of systemic IL-18 and IL-12 release during postoperative sepsis: high serum IL-18 as an early predictive indicator of lethal outcome.
Shock (Augusta, Ga.) 2002;18(4):301-5.
2002: Heike Weighardt; Simone Kaiser-Moore; Ramunas M Vabulas; Carsten J Kirschning; Hermann Wagner; Bernhard Holzmann
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(6):2823-7.
2002: Claus-Dieter Heidecke; Heike Weighardt; Marcus Feith; Ulrich Fink; Frank Zimmermann; Hubert J Stein; Jörg Rüdiger Siewert; Bernhard Holzmann
Neoadjuvant treatment of esophageal cancer: Immunosuppression following combined radiochemotherapy.
Surgery 2002;132(3):495-501.
2002: Dirk Gottschling; Jürgen Boer; Anja Schuster; Bernhard Holzmann; Horst Kessler
Combinatorial and rational strategies to develop nonpeptidic alpha4beta7-integrin antagonists from cyclic peptides.
Angewandte Chemie (International ed. in English) 2002;41(16):3007-11.
2002: Sandra Beer; Heike Weighardt; Klaus Emmanuilidis; Marit D Harzenetter; Edouard Matevossian; Claus-Dieter Heidecke; Holger Bartels; Jörg Rüdiger Siewert; Bernhard Holzmann
Systemic neuropeptide levels as predictive indicators for lethal outcome in patients with postoperative sepsis.
Critical care medicine 2002;30(8):1794-8.
2002: Dirk Gottschling; Jürgen Boer; Luciana Marinelli; Georg Voll; Melina Haupt; Anja Schuster; Bernhard Holzmann; Horst Kessler
Synthesis and NMR structure of peptidomimetic alpha4beta7-integrin antagonists.
Chembiochem : a European journal of chemical biology 2002;3(6):575-8.
2002: Marit D Harzenetter; Ulrich Keller; Sandra Beer; Claudia Riedl; Christian Peschel; Bernhard Holzmann
Regulation and function of the CGRP receptor complex in human granulopoiesis.
Experimental hematology 2002;30(4):306-12.
2002: Heike Weighardt; Claus-Dieter Heidecke; Alexandra Westerholt; Klaus Emmanuilidis; Stefan Maier; Martin Veit; Klaus Gerauer; Edouard Matevossian; Kurt Ulm; Jörg Rüdiger Siewert; Bernhard Holzmann
Impaired monocyte IL-12 production before surgery as a predictive factor for the lethal outcome of postoperative sepsis.
Annals of surgery 2002;235(4):560-7.
2001: Dirk Gottschling; Jürgen Boer; Anja Schuster; Bernhard Holzmann; Horst Kessler
Cellular solid-phase binding assay and mass spectrometry for screening of alpha 4 beta 7 integrin antagonists.
Bioorganic & medicinal chemistry letters 2001;11(23):2997-3000.
2001: Klaus Emmanuilidis; Heike Weighardt; Stefan Maier; Klaus Gerauer; T Fleischmann; X X Zheng; W W Hancock; Bernhard Holzmann; Claus-Dieter Heidecke
Critical role of Kupffer cell-derived IL-10 for host defense in septic peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):3919-27.
2001: Jürgen Boer; Dirk Gottschling; Anja Schuster; Monika Semmrich; Bernhard Holzmann; Horst Kessler
Design and synthesis of potent and selective alpha(4)beta(7) integrin antagonists.
Journal of medicinal chemistry 2001;44(16):2586-92.
2001: S Beer; A B Simins; A Schuster; Bernhard Holzmann
Molecular cloning and characterization of a novel SH3 protein (SLY) preferentially expressed in lymphoid cells.
Biochimica et biophysica acta 2001;1520(1):89-93.
2001: Carolin Feterowski; Heike Weighardt; Klaus Emmanuilidis; Thomas Hartung; Bernhard Holzmann
Immune protection against septic peritonitis in endotoxin-primed mice is related to reduced neutrophil apoptosis.
European journal of immunology 2001;31(4):1268-77.
2000: Heike Weighardt; Carolin Feterowski; M Veit; Martina Rump; Hermann Wagner; Bernhard Holzmann
Increased resistance against acute polymicrobial sepsis in mice challenged with immunostimulatory CpG oligodeoxynucleotides is related to an enhanced innate effector cell response.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(8):4537-43.
2000: W Barthlen; C Klemens; S Rogenhofer; J Stadler; N Unbehaun; Bernhard Holzmann
Critical role of nitric oxide for proliferation and apoptosis of bone-marrow cells under septic conditions.
Annals of hematology 2000;79(5):249-54.
2000: Heike Weighardt; Claus-Dieter Heidecke; Klaus Emmanuilidis; Stefan Maier; Holger Bartels; Jörg Rüdiger Siewert; Bernhard Holzmann
Sepsis after major visceral surgery is associated with sustained and interferon-gamma-resistant defects of monocyte cytokine production.
Surgery 2000;127(3):309-15.
2000: Robert B Brauer; C Gegenfurtner; B Neumann; M Stadler; Claus-Dieter Heidecke; Bernhard Holzmann
Endotoxin-induced lung inflammation is independent of the complement membrane attack complex.
Infection and immunity 2000;68(3):1626-32.
2000: Claus-Dieter Heidecke; Heike Weighardt; T Hensler; Holger Bartels; Bernhard Holzmann
[Immune paralysis of T-lymphocytes and monocytes in postoperative abdominal sepsis. Correlation of immune function with survival].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2000;71(2):159-65.
1999: Claus-Dieter Heidecke; T Hensler; Heike Weighardt; N Zantl; Hermann Wagner; Jörg Rüdiger Siewert; Bernhard Holzmann
Selective defects of T lymphocyte function in patients with lethal intraabdominal infection.
American journal of surgery 1999;178(4):288-92.
1999: W Barthlen; N Zantl; K Pfeffer; Claus-Dieter Heidecke; Bernhard Holzmann; Josef Stadler
Impact of experimental peritonitis on bone marrow cell function.
Surgery 1999;126(1):41-7.
1999: U Gosslar; R M Schmid; Bernhard Holzmann
Regulation of Egr-1-dependent gene expression by the C-terminal activation domain.
Biochemical and biophysical research communications 1999;255(2):208-15.
1999: B Neumann; N Zantl; A Veihelmann; Klaus Emmanuilidis; Klaus Pfeffer; Claus-Dieter Heidecke; Bernhard Holzmann
Mechanisms of acute inflammatory lung injury induced by abdominal sepsis.
International immunology 1999;11(2):217-27.
1999: A B Simins; Heike Weighardt; K M Weidner; U H Weidle; Bernhard Holzmann
Functional cloning of ARM-1, an adhesion-regulating molecule upregulated in metastatic tumor cells.
Clinical & experimental metastasis 1999;17(8):641-8.
1999: IB Brune; W Wilke; T Hensler; Bernhard Holzmann; Jörg Rüdiger Siewert
Downregulation of T helper type 1 immune response and altered pro-inflammatory and anti-inflammatory T cell cytokine balance following conventional but not laparoscopic surgery.
American journal of surgery 1999;177(1):55-60.
1998: B Neumann; Klaus Emmanuilidis; M Stadler; Bernhard Holzmann
Distinct functions of interferon-gamma for chemokine expression in models of acute lung inflammation.
Immunology 1998;95(4):512-21.
1998: M Bittner; U Gosslar; A Luz; Bernhard Holzmann
Sequence motifs in the integrin alpha 4 cytoplasmic tail required for regulation of in vivo expansion of murine lymphoma cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):5978-86.
1998: M Rietzler; M Bittner; W Kolanus; A Schuster; Bernhard Holzmann
The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins.
The Journal of biological chemistry 1998;273(42):27459-66.
1998: T Hensler; Claus-Dieter Heidecke; H Hecker; K Heeg; Holger Bartels; N Zantl; Hermann Wagner; Jörg Rüdiger Siewert; Bernhard Holzmann
Increased susceptibility to postoperative sepsis in patients with impaired monocyte IL-12 production.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(5):2655-9.
1998: IB Brune; W Wilke; T Hensler; Hubertus Feussner; Bernhard Holzmann; Jörg Rüdiger Siewert
Normal T lymphocyte and monocyte function after minimally invasive surgery.
Surgical endoscopy 1998;12(8):1020-4.
1998: P Jonas; Bernhard Holzmann; D Jablonski-Westrich; A Hamann
Dissemination capacity of murine lymphoma cells is not dependent on efficient homing.
International journal of cancer. Journal international du cancer 1998;77(3):402-7.
1998: N Zantl; A Uebe; B Neumann; Hermann Wagner; Jörg Rüdiger Siewert; Bernhard Holzmann; Claus-Dieter Heidecke; Klaus Pfeffer
Essential role of gamma interferon in survival of colon ascendens stent peritonitis, a novel murine model of abdominal sepsis.
Infection and immunity 1998;66(5):2300-9.
1998: N Unbehaun; W Barthlen; W Kaffenberger; Bernhard Holzmann; Holger Bartels; Jörg Rüdiger Siewert
[Respiratory burst and phagocytosis activity in patients with infection after surgical abdominal interventions].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115(Suppl I):457-9.
1998: Holger Bartels; N Zantl; Bernhard Holzmann; Jörg Rüdiger Siewert
[Special therapeutic approaches for interrupting the cascade--from systemic inflammatory response syndrome to multiple organ failure].
Langenbecks Archiv für Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft für Chirurgie. Kongress 1998;115():615-8.
1998: Bernhard Holzmann; U Gosslar; Michael Bittner
alpha 4 integrins and tumor metastasis.
Current topics in microbiology and immunology 1998;231():125-41.
1997: T Hensler; H Hecker; K Heeg; Claus-Dieter Heidecke; Holger Bartels; W Barthlen; Hermann Wagner; Jörg Rüdiger Siewert; Bernhard Holzmann
Distinct mechanisms of immunosuppression as a consequence of major surgery.
Infection and immunity 1997;65(6):2283-91.
1997: B Neumann; B Engelhardt; Hermann Wagner; Bernhard Holzmann
Induction of acute inflammatory lung injury by staphylococcal enterotoxin B.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(4):1862-71.
1997: G Kilger; J Clements; Bernhard Holzmann
Amino acid residues required for binding of vascular cell adhesion molecule-1 to integrin alpha 4 beta 7.
International immunology 1997;9(2):219-26.
1996: B Neumann; A Luz; Klaus Pfeffer; Bernhard Holzmann
Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor.
The Journal of experimental medicine 1996;184(1):259-64.
1996: U Gosslar; P Jonas; A Luz; A Lifka; David Naor; A Hamann; Bernhard Holzmann
Predominant role of alpha 4-integrins for distinct steps of lymphoma metastasis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):4821-6.
1996: B Neumann; thomas machleidt; A Lifka; Klaus Pfeffer; D Vestweber; T W Mak; Bernhard Holzmann; M Krönke
Crucial role of 55-kilodalton TNF receptor in TNF-induced adhesion molecule expression and leukocyte organ infiltration.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(4):1587-93.
1995: G Kilger; Bernhard Holzmann
Molecular analysis of the physiological and pathophysiological role of alpha 4-integrins.
Journal of molecular medicine (Berlin, Germany) 1995;73(7):347-54.
1995: M A Zahalka; E Okon; U Gosslar; Bernhard Holzmann; David Naor
Lymph node (but not spleen) invasion by murine lymphoma is both CD44- and hyaluronate-dependent.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(10):5345-55.
1995: G Kilger; L A Needham; P J Nielsen; J Clements; D Vestweber; Bernhard Holzmann
Differential regulation of alpha 4 integrin-dependent binding to domains 1 and 4 of vascular cell adhesion molecule-1.
The Journal of biological chemistry 1995;270(11):5979-84.
1995: J Stadler; Claus-Dieter Heidecke; H Bartels; Bernhard Holzmann; H Wagner; Jörg Rüdiger Siewert
[Immunosuppression and infection].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1995;66(1):11-7.
1994: David Andrew; C Berlin; S Honda; T Yoshino; A Hamann; Bernhard Holzmann; P J Kilshaw; Eugene C Butcher
Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(9):3847-61.
1994: A Hamann; David Andrew; D Jablonski-Westrich; Bernhard Holzmann; E C Butcher
Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(7):3282-93.
1994: U G Strauch; A Lifka; U Gosslar; P J Kilshaw; J Clements; Bernhard Holzmann
Distinct binding specificities of integrins alpha 4 beta 7 (LPAM-1), alpha 4 beta 1 (VLA-4), and alpha IEL beta 7.
International immunology 1994;6(2):263-75.
1993: T Miethke; C Wahl; Bernhard Holzmann; Klaus Heeg; H Wagner
Bacterial superantigens induce rapid and T cell receptor V beta-selective down-regulation of L-selectin (gp90Mel-14) in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(12):6777-82.
1993: C Berlin; Ellen L Berg; Michael Briskin; David Andrew; P J Kilshaw; Bernhard Holzmann; Irving L Weissman; A Hamann; Eugene C Butcher
Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.
Cell 1993;74(1):185-95.
1993: U G Strauch; Bernhard Holzmann
Triggering of L-selectin (gp90MEL-14) induces homotypic lymphocyte adhesion by a mechanism independent of LFA-1.
International immunology 1993;5(4):393-8.
1993: M C Hu; Bernhard Holzmann; D T Crowe; H Neuhaus; Irving L Weissman
The Peyer's patch homing receptor.
Current topics in microbiology and immunology 1993;184():125-38.
1992: M C Hu; D T Crowe; Irving L Weissman; Bernhard Holzmann
Cloning and expression of mouse integrin beta p(beta 7): a functional role in Peyer's patch-specific lymphocyte homing.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8254-8.
1992: C Bührer; C Berlin; D Jablonski-Westrich; Bernhard Holzmann; HG Thiele; A Hamann
Lymphocyte activation and regulation of three adhesion molecules with supposed function in homing: LECAM-1 (MEL-14 antigen), LPAM-1/2 (alpha 4-integrin) and CD44 (Pgp-1).
Scandinavian journal of immunology 1992;35(1):107-20.
1992: M C Hu; M H Siegelman; Bernhard Holzmann; D T Crowe; Irving L Weissman
Lymphocyte homing receptors.
Cold Spring Harbor symposia on quantitative biology 1992;57():291-308.
1991: H Neuhaus; M C Hu; Martin Helmer; Yoshikazu Takada; Bernhard Holzmann; Irving L Weissman
Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule.
The Journal of cell biology 1991;115(4):1149-58.
1991: T Kina; A S Majumdar; S Heimfeld; H Kaneshima; Bernhard Holzmann; Y Katsura; Irving L Weissman
Identification of a 107-kD glycoprotein that mediates adhesion between stromal cells and hematolymphoid cells.
The Journal of experimental medicine 1991;173(2):373-81.
1990: Craig Y Okada; Bernhard Holzmann; Cynthia J Guidos; E Palmer; Irving L Weissman
Characterization of a rat monoclonal antibody specific for a determinant encoded by the V beta 7 gene segment. Depletion of V beta 7+ T cells in mice with Mls-1a haplotype.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3473-7.
1989: Bernhard Holzmann; Irving L Weissman
Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel.
The EMBO journal 1989;8(6):1735-41.
1989: Bernhard Holzmann; Irving L Weissman
Integrin molecules involved in lymphocyte homing to Peyer's patches.
Immunological reviews 1989;108():45-61.
1989: Bernhard Holzmann; B W McIntyre; Irving L Weissman
Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha.
Cell 1989;56(1):37-46.
1989: S Heimfeld; Cynthia J Guidos; Bernhard Holzmann; M H Siegelman; Irving L Weissman
Developmental analysis of the mouse hematolymphoid system.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 1():75-85.
1988: B T Sher; Robert Bargatze; Bernhard Holzmann; W M Gallatin; D Matthews; N Wu; Louis J Picker; Eugene C Butcher; Irving L Weissman
Homing receptors and metastasis.
Advances in cancer research 1988;51():361-90.