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Till Acker

Research Profile

Chemicals & Drugs

Disorders

Neovascularization, Pathologic

Procedures

Living Beings

Mouse

Physiology

Cell Hypoxia

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Publications

TOP 3
Martin Berghoff; Benjamin Dassinger; Elke R Gizewski; Gerhard C Hildebrandt; Manfred Kaps; Gothje Klappstein; Anne Schänzer; Till Acker; Astrid Grams
Development of progressive multifocal leukoencephalopathy in a patient with non-Hodgkin lymphoma 13 years after treatment with cladribine.
Matthias Preusser; Margaretha Rudas; Georg Widhalm; Karl H Plate; Till Acker; Johannes Berger; Peter Birner; Helene Breitschopf; Marco Hassler; Engelbert Knosp; Christine Marosi
Microvascularization and expression of VEGF and its receptors in recurring meningiomas: pathobiological data in favor of anti-angiogenic therapy approaches.
Suphansa Sawamiphak; Sascha Seidel; Clara L Essmann; George A Wilkinson; Mara E Pitulescu; Till Acker; Amparo Acker-Palmer
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis.

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All Publications

2013: Martin Berghoff; Benjamin Dassinger; Elke R Gizewski; Gerhard C Hildebrandt; Manfred Kaps; Gothje Klappstein; Anne Schänzer; Till Acker; Astrid Grams
Development of progressive multifocal leukoencephalopathy in a patient with non-Hodgkin lymphoma 13 years after treatment with cladribine.
Leukemia & lymphoma 2013;54(6):1340-2.
2012: Matthias Preusser; Margaretha Rudas; Georg Widhalm; Karl H Plate; Till Acker; Johannes Berger; Peter Birner; Helene Breitschopf; Marco Hassler; Engelbert Knosp; Christine Marosi
Microvascularization and expression of VEGF and its receptors in recurring meningiomas: pathobiological data in favor of anti-angiogenic therapy approaches.
Clinical neuropathology 2012;31(5):352-60.
2010: Suphansa Sawamiphak; Sascha Seidel; Clara L Essmann; George A Wilkinson; Mara E Pitulescu; Till Acker; Amparo Acker-Palmer
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis.
Nature 2010;465(7297):487-91.
2008: Valentina Câmpean; Britta Karpe; Christian Haas; Akram Atalla; Harm Peters; Harald Rupprecht; Stefan Liebner; Till Acker; Karl H Plate; Kerstin Amann
Angiopoietin 1 and 2 gene and protein expression is differentially regulated in acute anti-Thy1.1 glomerulonephritis.
American journal of physiology. Renal physiology 2008;294(5):F1174-84.
2007: Amina Comati; Heike Beck; William Halliday; G Jackson Snipes; Karl H Plate; Till Acker
Upregulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha in leptomeningeal vascular malformations of Sturge-Weber syndrome.
Journal of neuropathology and experimental neurology 2007;66(1):86-97.
2007: Christian S Haas; Valentina Câmpean; Alexander Kuhlmann; Arno Dimmler; Udo Reulbach; Christian Forster; Thomas Aigner; Till Acker; Karl H Plate; Kerstin Amann
Analysis of glomerular VEGF mRNA and protein expression in murine mesangioproliferative glomerulonephritis.
Virchows Archiv : an international journal of pathology 2007;450(1):81-92.
2006: Till Acker; Joachim Fandrey; Helmut Acker
The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases.
Cardiovascular research 2006;71(2):195-207.
2006: Amedeo A Azizi; Christine Haberler; Thomas Czech; Astrid Gupper; Daniela Prayer; Helene Breitschopf; Till Acker; Irene Slavc
Vascular-endothelial-growth-factor (VEGF) expression and possible response to angiogenesis inhibitor bevacizumab in metastatic alveolar soft part sarcoma.
The lancet oncology 2006;7(6):521-3.
2005: Till Acker; Antonio Diez-juan; Julian Aragones; Marc Tjwa; Koen Brusselmans; Lieve Moons; Dai Fukumura; Maria Paz Moreno-Murciano; Jean-Marc Herbert; Angelika Burger; Johanna Riedel; Gerd Elvert; Ingo Flamme; Patrick H Maxwell; Désiré Collen; Mieke Dewerchin; Rakesh K Jain; Karl H Plate; Peter Carmeliet
Genetic evidence for a tumor suppressor role of HIF-2alpha.
Cancer cell 2005;8(2):131-41.
2005: Matthias Preusser; Stefan Wolfsberger; Christine Haberler; Helene Breitschopf; Thomas Czech; Irene Slavc; Adrian L Harris; Till Acker; Herbert Budka; Johannes A Hainfellner
Vascularization and expression of hypoxia-related tissue factors in intracranial ependymoma and their impact on patient survival.
Acta neuropathologica 2005;109(2):211-6.
2004: Peter Birner; Matthias Preusser; Ellen Gelpi; Johannes Berger; Brigitte Gatterbauer; Inge M Ambros; Peter F Ambros; Till Acker; Karl H Plate; Adrian L Harris; Johannes A Hainfellner
Expression of hypoxia-related tissue factors correlates with diminished survival of adjuvantly treated patients with chromosome 1p aberrant oligodendroglial neoplasms and therapeutic implications.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(19):6567-71.
2004: Till Acker; Helmut Acker
Cellular oxygen sensing need in CNS function: physiological and pathological implications.
The Journal of experimental biology 2004;207(Pt 18):3171-88.
2004: Oliver Distler; Jörg H W Distler; Annette Scheid; Till Acker; Astrid Hirth; Janine Rethage; Beat A Michel; Renate E Gay; Ulf Müller-Ladner; Marco Matucci-Cerinic; Karl H Plate; Max Gassmann; Steffen Gay
Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis.
Circulation research 2004;95(1):109-16.
2004: Anne Schänzer; Frank-Peter Wachs; Daniel Wilhelm; Till Acker; Christiana Cooper-Kuhn; Heike Beck; Jürgen Winkler; Ludwig Aigner; Karl H Plate; H Georg Kuhn
Direct stimulation of adult neural stem cells in vitro and neurogenesis in vivo by vascular endothelial growth factor.
Brain pathology (Zurich, Switzerland) 2004;14(3):237-48.
2004: Stefan Probst-Cousin; Till Acker; J T Epplen; Markus Bergmann; Karl H Plate; Bernhard Neundörfer; Dieter Heuss
Spinocerebellar ataxia type 2 with glial cell cytoplasmic inclusions.
Journal of neurology, neurosurgery, and psychiatry 2004;75(3):503-5.
2004: Till Acker; Karl H Plate
Hypoxia and hypoxia inducible factors (HIF) as important regulators of tumor physiology.
Cancer treatment and research 2004;117():219-48.
2003: Till Acker; Karl H Plate
Role of hypoxia in tumor angiogenesis-molecular and cellular angiogenic crosstalk.
Cell and tissue research 2003;314(1):145-55.
2003: Heike Beck; Robert Voswinckel; Shawn Wagner; Tibor Ziegelhoeffer; Matthias Heil; Armin Helisch; Wolfgang Schaper; Till Acker; Antonis K Hatzopoulos; Karl H Plate
Participation of bone marrow-derived cells in long-term repair processes after experimental stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2003;23(6):709-17.
2003: Gerd Elvert; Andreas Kappel; Regina Heidenreich; Ursula Englmeier; Stephan Lanz; Till Acker; Manuel Rauter; Karl H Plate; Michael H Sieweke; Georg Breier; Ingo Flamme
Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1).
The Journal of biological chemistry 2003;278(9):7520-30.
2002: Till Acker; Karl H Plate
A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology.
Journal of molecular medicine (Berlin, Germany) 2002;80(9):562-75.
2002: Veerle Compernolle; Koen Brusselmans; Till Acker; Peter Hoet; Marc Tjwa; Heike Beck; Stephane Plaisance; Yuval Dor; Eli Keshet; Florea Lupu; Benoit Nemery; Mieke Dewerchin; Paul P Van Veldhoven; Karl H Plate; Lieve Moons; Désiré Collen; Peter Carmeliet
Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice.
Nature medicine 2002;8(7):702-10.
2002: Heike Beck; Till Acker; Andreas W Püschel; Hajime Fujisawa; Peter Carmeliet; Karl H Plate
Cell type-specific expression of neuropilins in an MCA-occlusion model in mice suggests a potential role in post-ischemic brain remodeling.
Journal of neuropathology and experimental neurology 2002;61(4):339-50.
2001: Till Acker; Heike Beck; Karl H Plate
Cell type specific expression of vascular endothelial growth factor and angiopoietin-1 and -2 suggests an important role of astrocytes in cerebellar vascularization.
Mechanisms of development 2001;108(1-2):45-57.
2001: Peter Carmeliet; Lieve Moons; Aernout Luttun; V Vincenti; Veerle Compernolle; Maria De Mol; Y Wu; Françoise Bono; Laetitia Devy; Heike Beck; Dimitri Scholz; Till Acker; T DiPalma; Mieke Dewerchin; Agnès Noel; Ingeborg Stalmans; A Barra; Silvia Blacher; Thierry VandenDriessche; A Ponten; Ulf Eriksson; Karl H Plate; Jean-Michel Foidart; Wolfgang Schaper; D S Charnock-Jones; Daniel J Hicklin; Jean-Marc Herbert; Désiré Collen; M Graziella Persico
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.
Nature medicine 2001;7(5):575-83.
2001: Manfred Kunz; S Ibrahim; D Koczan; H J Thiesen; H J Köhler; Till Acker; K H Plate; Stephan Ludwig; Ulf R Rapp; E B Bröcker; G N van Muijen; Egbert Flory; G Gross
Activation of c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK) is critical for hypoxia-induced apoptosis of human malignant melanoma.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001;12(3):137-45.
2001: A Stratmann; Till Acker; Angelika Burger; K Amann; Werner Risau; Karl H Plate
Differential inhibition of tumor angiogenesis by tie2 and vascular endothelial growth factor receptor-2 dominant-negative receptor mutants.
International journal of cancer. Journal international du cancer 2001;91(3):273-82.
2000: M Krieg; R Haas; Hiltrud Brauch; Till Acker; Ingo Flamme; Karl H Plate
Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Oncogene 2000;19(48):5435-43.
2000: Heike Beck; Till Acker; Christoph Wiessner; Peter R Allegrini; Karl H Plate
Expression of angiopoietin-1, angiopoietin-2, and tie receptors after middle cerebral artery occlusion in the rat.
The American journal of pathology 2000;157(5):1473-83.