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Helen Atkins

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Kay B Barnes; Carwyn H Davies; Sarah V Harding; Thomas R Laws; M Stephen Lever; Neil Roughley; Andrew J H Simpson; Jackie Steward; Joanne E Thwaite; Stuart J Armstrong; Timothy P Atkins; Helen S Atkins
Trimethoprim/sulfamethoxazole (co-trimoxazole) prophylaxis is effective against acute murine inhalational melioidosis and glanders.
Helen Flick-Smith; Marc A Fox; Karleigh A Hamblin; Sarah V Harding; Dominic C Jenner; Thomas R Laws; Amanda L Phelps; Mark I Richards; Christopher Taylor; DO Ulaeto; Helen S Atkins
Assessment of antimicrobial peptide LL-37 as a post-exposure therapy to protect against respiratory tularemia in mice.
Rachael J Thomas; Stuart J Armstrong; Helen S Atkins; Monika Bokori-Brown; Stan Goldman; Karleigh A Hamblin; Claudia M Müller; Richard W Titball
Galleria mellonella as a model system to test the pharmacokinetics and efficacy of antibiotics against Burkholderia pseudomallei.

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2013: Kay B Barnes; Carwyn H Davies; Sarah V Harding; Thomas R Laws; M Stephen Lever; Neil Roughley; Andrew J H Simpson; Jackie Steward; Joanne E Thwaite; Stuart J Armstrong; Timothy P Atkins; Helen S Atkins
Trimethoprim/sulfamethoxazole (co-trimoxazole) prophylaxis is effective against acute murine inhalational melioidosis and glanders.
International journal of antimicrobial agents 2013;41(6):552-7.
2013: Helen Flick-Smith; Marc A Fox; Karleigh A Hamblin; Sarah V Harding; Dominic C Jenner; Thomas R Laws; Amanda L Phelps; Mark I Richards; Christopher Taylor; DO Ulaeto; Helen S Atkins
Assessment of antimicrobial peptide LL-37 as a post-exposure therapy to protect against respiratory tularemia in mice.
Peptides 2013;43():96-101.
2013: Rachael J Thomas; Stuart J Armstrong; Helen S Atkins; Monika Bokori-Brown; Stan Goldman; Karleigh A Hamblin; Claudia M Müller; Richard W Titball
Galleria mellonella as a model system to test the pharmacokinetics and efficacy of antibiotics against Burkholderia pseudomallei.
International journal of antimicrobial agents 2013;41(4):330-6.
2013: Rohini R Rana; Abigail M Spear; Minghao Zhang; Helen S Atkins; Bernadette Byrne
Bacterial TIR-containing proteins and host innate immune system evasion.
Medical microbiology and immunology 2013;202(1):1-10.
2012: Abigail M Spear; Bernadette Byrne; Helen Flick-Smith; Dominic C Jenner; Stephen J Matthews; Petra C F Oyston; Rohini R Rana; Peter Simpson; Helen S Atkins
A Toll/interleukin (IL)-1 receptor domain protein from Yersinia pestis interacts with mammalian IL-1/Toll-like receptor pathways but does not play a central role in the virulence of Y. pestis in a mouse model of bubonic plague.
Microbiology (Reading, England) 2012;158(Pt 6):1593-606.
2012: Marc A Fox; Joanne E Thwaite; DO Ulaeto; Timothy P Atkins; Helen S Atkins
Design and characterization of novel hybrid antimicrobial peptides based on cecropin A, LL-37 and magainin II.
Peptides 2012;33(2):197-205.
2011: Thomas R Laws; Roman A Lukaszewski; Sophie J Smither; Helen S Atkins
Neutrophils are the predominant cell-type to associate with Burkholderia pseudomallei in a BALB/c mouse model of respiratory melioidosis.
Microbial pathogenesis 2011;51(6):471-5.
2011: Rohini R Rana; Peter Simpson; Abigail M Spear; Chimaka Ukegbu; Minghao Zhang; Yilmaz Alguel; Helen S Atkins; Matthew Jennions; Stephen J Matthews; Bernadette Byrne
Yersinia pestis TIR-domain protein forms dimers that interact with the human adaptor protein MyD88.
Microbial pathogenesis 2011;51(3):89-95.
2011: Mitali Sarkar-Tyson; Helen S Atkins
Antimicrobials for bacterial bioterrorism agents.
Future microbiology 2011;6(6):667-76.
2011: Karen K Chu; Patcharaporn Tippayawat; Nicola J Walker; Sarah V Harding; Helen S Atkins; Bernard Maillere; Gregory J Bancroft; Ganjana Lertmemongkolchai; Daniel M Altmann
CD4+ T-cell immunity to the Burkholderia pseudomallei ABC transporter LolC in melioidosis.
European journal of immunology 2011;41(1):107-15.
2010: Dermot J Kenny; Armine M Sefton; Timothy J G Brooks; Thomas R Laws; Andrew J H Simpson; Helen S Atkins
Evaluation of azithromycin, trovafloxacin and grepafloxacin as prophylaxis for experimental murine melioidosis.
International journal of antimicrobial agents 2010;36(1):87-9.
2010: Helen S Atkins; Stephen Spencer; Simon D Brew; Dominic C Jenner; Armine M Sefton; Alastair P MacMillan; Timothy J G Brooks; Andrew J H Simpson
Evaluation of azithromycin, trovafloxacin and grepafloxacin as prophylaxis against experimental murine Brucella melitensis infection.
International journal of antimicrobial agents 2010;36(1):66-8.
2010: Stuart D Perkins; Sophie J Smither; Helen S Atkins
Towards a Brucella vaccine for humans.
FEMS microbiology reviews 2010;34(3):379-94.
2010: Petra C F Oyston; Gabriela Mellado-Sanchez; Marcela F Pasetti; James P Nataro; Richard W Titball; Helen S Atkins
A Yersinia pestis guaBA mutant is attenuated in virulence and provides protection against plague in a mouse model of infection.
Microbial pathogenesis 2010;48(5):191-5.
2009: Dermot J Kenny; Armine M Sefton; Jackie Steward; Timothy J G Brooks; Andrew J H Simpson; Helen S Atkins
Efficacy of the quinolones trovafloxacin and grepafloxacin for therapy of experimental tularaemia and plague.
International journal of antimicrobial agents 2009;34(5):502-3.
2009: Helen S Atkins; Stephen Spencer; Simon D Brew; Thomas R Laws; Rachel E Thirlwall; Alastair P MacMillan; Timothy J G Brooks; Andrew J H Simpson
Efficacy of moxifloxacin or gatifloxacin as prophylaxis against experimental murine Brucella melitensis infection.
International journal of antimicrobial agents 2009;34(5):471-3.
2009: Helen S Atkins; Stephen Spencer; Simon D Brew; Dominic C Jenner; Paul Russell; Alastair P MacMillan; Stephen M Eley; Andrew J H Simpson
Efficacy of ciprofloxacin versus doxycycline as prophylaxis against experimental murine Brucella melitensis infection.
International journal of antimicrobial agents 2009;34(5):474-6.
2009: Claire Vernazza; Bry Lingard; Helen Flick-Smith; Les Baillie; Jim Hill; Helen S Atkins
Small protective fragments of the Yersinia pestis V antigen.
Vaccine 2009;27(21):2775-80.
2009: Sophie J Smither; Stuart D Perkins; Carwyn Davies; Anthony J Stagg; Michelle Nelson; Helen S Atkins
Development and characterization of mouse models of infection with aerosolized Brucella melitensis and Brucella suis.
Clinical and vaccine immunology : CVI 2009;16(5):779-83.
2009: Joanne E Thwaite; T R Laws; Timothy P Atkins; Helen S Atkins
Differential cell surface properties of vegetative Bacillus.
Letters in applied microbiology 2009;48(3):373-8.
2009: Dominic C Jenner; Elie Dassa; Adrian M Whatmore; Helen S Atkins
ATP-Binding Cassette Systems of Brucella.
Comparative and functional genomics 2009;():354649.
2007: Mikio Tanabe; Osman Mirza; Thomas Bertrand; Helen S Atkins; Richard Titball; So Iwata; Katherine A Brown; Bernadette Byrne
Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 11):1185-93.
2007: Brendan N Neeson; Graeme C Clark; Helen S Atkins; Bryan Lingard; Richard Titball
Analysis of protection afforded by a Clostridium perfringens alpha-toxoid against heterologous clostridial phospholipases C.
Microbial pathogenesis 2007;43(4):161-5.
2007: David N Harland; Karen Chu; Ashraful Haque; Michelle Nelson; Nicola J Walker; Mitali Sarkar-Tyson; Timothy P Atkins; Benjamin Moore; Katherine A Brown; Gregory Bancroft; Richard Titball; Helen S Atkins
Identification of a LolC homologue in Burkholderia pseudomallei, a novel protective antigen for melioidosis.
Infection and immunity 2007;75(8):4173-80.
2007: Margaret G M Stokes; Richard Titball; Brendan N Neeson; James E Galen; Nicola J Walker; Andrew J Stagg; Dominic C Jenner; Joanne E Thwaite; James P Nataro; Les Baillie; Helen S Atkins
Oral administration of a Salmonella enterica-based vaccine expressing Bacillus anthracis protective antigen confers protection against aerosolized B. anthracis.
Infection and immunity 2007;75(4):1827-34.
2007: David N Harland; Elie Dassa; Richard Titball; Katherine A Brown; Helen S Atkins
ATP-binding cassette systems in Burkholderia pseudomallei and Burkholderia mallei.
BMC genomics 2007;8():83.
2006: Helen S Atkins; Elie Dassa; Nicola J Walker; Kate F Griffin; David N Harland; Rosa R Taylor; Melanie L Duffield; Richard Titball
The identification and evaluation of ATP binding cassette systems in the intracellular bacterium Francisella tularensis.
Research in microbiology 2006;157(6):593-604.
2006: Mikio Tanabe; Helen S Atkins; David N Harland; Stephen J Elvin; Andrew J Stagg; Osman Mirza; Richard Titball; Bernadette Byrne; Katherine A Brown
The ABC transporter protein OppA provides protection against experimental Yersinia pestis infection.
Infection and immunity 2006;74(6):3687-91.
2006: Thomas R Laws; Helen S Atkins; Timothy P Atkins; Richard Titball
The pathogen Pseudomonas aeruginosa negatively affects the attraction response of the nematode Caenorhabditis elegans to bacteria.
Microbial pathogenesis 2006;40(6):293-7.
2006: Helen S Atkins; Margaret Morton; Kate F Griffin; Margaret G M Stokes; James P Nataro; Richard Titball
Recombinant Salmonella vaccines for biodefence.
Vaccine 2006;24(15):2710-7.