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Manabu Horikawa

Research Profile

Chemicals & Drugs

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Quorum Sensing

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Natsue Hosono Honda; Soichiro Kimura; Kazuhiro Tateda; Manabu Horikawa; Chihiro Ueda; Yoshikazu Ishii; Masaji Ishiguro; Shinichi Miyairi; Keizo Yamaguchi
Roles of Pseudomonas aeruginosa autoinducers and their degradation products, tetramic acids, in bacterial survival and behavior in ecological niches.
Chihiro Ueda; Kazuhiro Tateda; Manabu Horikawa; Soichiro Kimura; Yoshikazu Ishii; Kaoru Nomura; Kanako Yamada; Takashi Suematsu; Yasuhisa Inoue; Masaji Ishiguro; Shinichi Miyairi; Keizo Yamaguchi
Anti-Clostridium difficile potential of tetramic acid derivatives from Pseudomonas aeruginosa quorum-sensing autoinducers.
Soichiro Kimura; Kazuhiro Tateda; Yoshikazu Ishii; Manabu Horikawa; Shinichi Miyairi; Naomasa Gotoh; Masaji Ishiguro; Keizo Yamaguchi
Pseudomonas aeruginosa Las quorum sensing autoinducer suppresses growth and biofilm production in Legionella species.

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All Publications

2011: Natsue Hosono Honda; Soichiro Kimura; Kazuhiro Tateda; Manabu Horikawa; Chihiro Ueda; Yoshikazu Ishii; Masaji Ishiguro; Shinichi Miyairi; Keizo Yamaguchi
Roles of Pseudomonas aeruginosa autoinducers and their degradation products, tetramic acids, in bacterial survival and behavior in ecological niches.
Microbes and environments / JSME 2011;26(2):160-4.
2010: Chihiro Ueda; Kazuhiro Tateda; Manabu Horikawa; Soichiro Kimura; Yoshikazu Ishii; Kaoru Nomura; Kanako Yamada; Takashi Suematsu; Yasuhisa Inoue; Masaji Ishiguro; Shinichi Miyairi; Keizo Yamaguchi
Anti-Clostridium difficile potential of tetramic acid derivatives from Pseudomonas aeruginosa quorum-sensing autoinducers.
Antimicrobial agents and chemotherapy 2010;54(2):683-8.
2009: Soichiro Kimura; Kazuhiro Tateda; Yoshikazu Ishii; Manabu Horikawa; Shinichi Miyairi; Naomasa Gotoh; Masaji Ishiguro; Keizo Yamaguchi
Pseudomonas aeruginosa Las quorum sensing autoinducer suppresses growth and biofilm production in Legionella species.
Microbiology (Reading, England) 2009;155(Pt 6):1934-9.
2007: Kazuhiro Tateda; Yoshikazu Ishii; Soichiro Kimura; Manabu Horikawa; Shinichi Miyairi; Keizo Yamaguchi
Suppression of Pseudomonas aeruginosa quorum-sensing systems by macrolides: a promising strategy or an oriental mystery?
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2007;13(6):357-67.
2006: Shinichi Miyairi; Kazuhiro Tateda; Etsu T Fuse; Chihiro Ueda; Hiroaki Saito; Tohru Takabatake; Yoshikazu Ishii; Manabu Horikawa; Masaji Ishiguro; Theodore J Standiford; Keizo Yamaguchi
Immunization with 3-oxododecanoyl-L-homoserine lactone-protein conjugate protects mice from lethal Pseudomonas aeruginosa lung infection.
Journal of medical microbiology 2006;55(Pt 10):1381-7.
2006: Manabu Horikawa; Kazuhiro Tateda; Etsu Tuzuki; Yoshikazu Ishii; Chihiro Ueda; Tohru Takabatake; Shinichi Miyairi; Keizou Yamaguchi; Masaji Ishiguro
Synthesis of Pseudomonas quorum-sensing autoinducer analogs and structural entities required for induction of apoptosis in macrophages.
Bioorganic & medicinal chemistry letters 2006;16(8):2130-3.
2003: Kazuhiro Tateda; Yoshikazu Ishii; Manabu Horikawa; Tetsuya Matsumoto; Shinichi Miyairi; Jean Claude Pechere; Theodore J Standiford; Masaji Ishiguro; Keizo Yamaguchi
The Pseudomonas aeruginosa autoinducer N-3-oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils.
Infection and immunity 2003;71(10):5785-93.