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Malcolm Horne

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Manal A Farg; Malcolm K Horne; Jacqueline Orian; Hong Pham; Kai Y Soo; Adam K Walker; Sadaf T Warraich; Kelly L Williams; Ian P Blair; Julie D Atkin
Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase.
Kai Y Soo; Adam K Walker; Julie D Atkin; Manal Farg; Malcolm K Horne; Phillip Nagley
Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis.
Yi Sui; Malcolm K Horne; Davor Stanić
Reduced proliferation in the adult mouse subventricular zone increases survival of olfactory bulb interneurons.

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2012: Manal A Farg; Malcolm K Horne; Jacqueline Orian; Hong Pham; Kai Y Soo; Adam K Walker; Sadaf T Warraich; Kelly L Williams; Ian P Blair; Julie D Atkin
Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase.
Neurobiology of aging 2012;33(12):2855-68.
2012: Kai Y Soo; Adam K Walker; Julie D Atkin; Manal Farg; Malcolm K Horne; Phillip Nagley
Bim links ER stress and apoptosis in cells expressing mutant SOD1 associated with amyotrophic lateral sclerosis.
PloS one 2012;7(4):e35413.
2012: Yi Sui; Malcolm K Horne; Davor Stanić
Reduced proliferation in the adult mouse subventricular zone increases survival of olfactory bulb interneurons.
PloS one 2012;7(2):e31549.
2011: Wah Chin Boon; Malcolm K Horne
Aromatase and its inhibition in behaviour, obsessive compulsive disorder and parkinsonism.
Steroids 2011;76(8):816-9.
2011: Joohyung Lee; Clare L Parish; Doris Tomas; Malcolm K Horne
Chronic cocaine administration reduces striatal dopamine terminal density and striatal dopamine release which leads to drug-seeking behaviour.
Neuroscience 2011;174():143-50.
2011: Tim D Aumann; Kate Egan; Jamie Lim; Wah C Boon; Chris R Bye; Hui K Chua; Natalija Baban; Clare L Parish; Larisa Bobrovskaya; Phillip Dickson; Malcolm K Horne
Neuronal activity regulates expression of tyrosine hydroxylase in adult mouse substantia nigra pars compacta neurons.
Journal of neurochemistry 2011;116(4):646-58.
2011: Wah Chin Boon; Malcolm K Horne; Richard Manasseh; Karolina Petkovic-Duran; Yonggang Zhu; Tim D Aumann
Increasing cDNA yields from single-cell quantities of mRNA in standard laboratory reverse transcriptase reactions using acoustic microstreaming.
Journal of visualized experiments : JoVE 2011;(53):e3144.
2011: Brette D Blakely; Christopher R Bye; Chathurini V Fernando; Malcolm K Horne; Maria L Macheda; Steven A Stacker; Ernest Arenas; Clare L Parish
Wnt5a regulates midbrain dopaminergic axon growth and guidance.
PloS one 2011;6(3):e18373.
2010: Chathurini V Fernando; David Moses; Clare L Parish; Doris Tomas; John Drago; Malcolm K Horne
Creating a ventral midbrain stem cell niche in an animal model for Parkinson's disease.
Stem cells and development 2010;19(12):1995-2007.
2010: Rogan B Tinsley; K Kotschet; D Modesto; H Ng; Y Wang; P Nagley; G Shaw; Malcolm K Horne
Sensitive and specific detection of α-synuclein in human plasma.
Journal of neuroscience research 2010;88(12):2693-700.
2010: DR Nisbet; Andrew E Rodda; Malcolm K Horne; John S Forsythe; David Finkelstein
Implantation of functionalized thermally gelling xyloglucan hydrogel within the brain: associated neurite infiltration and inflammatory response.
Tissue engineering. Part A 2010;16(9):2833-42.
2010: Malcolm K Horne; David R Nisbet; John S Forsythe; Clare L Parish
Three-dimensional nanofibrous scaffolds incorporating immobilized BDNF promote proliferation and differentiation of cortical neural stem cells.
Stem cells and development 2010;19(6):843-52.
2010: Adam K Walker; Manal A Farg; Chris R Bye; Catriona A McLean; Malcolm K Horne; Julie D Atkin
Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis.
Brain : a journal of neurology 2010;133(Pt 1):105-16.
2009: Rogan B Tinsley; Chris R Bye; Clare L Parish; Angela Tziotis-Vais; Sonia George; Janetta G Culvenor; Qiao-Xin Li; Colin L Masters; David Finkelstein; Malcolm K Horne
Dopamine D2 receptor knockout mice develop features of Parkinson disease.
Annals of neurology 2009;66(4):472-84.
2009: DR Nisbet; Andrew E Rodda; Malcolm K Horne; John S Forsythe; David Finkelstein
Neurite infiltration and cellular response to electrospun polycaprolactone scaffolds implanted into the brain.
Biomaterials 2009;30(27):4573-80.
2009: Yi Sui; Davor Stanić; Doris Tomas; Bevyn Jarrott; Malcolm K Horne
Meloxicam reduces lipopolysaccharide-induced degeneration of dopaminergic neurons in the rat substantia nigra pars compacta.
Neuroscience letters 2009;460(2):121-5.
2009: David R Nisbet; Andrew E Rodda; David Finkelstein; Malcolm K Horne; John S Forsythe; Wei Shen
Surface and bulk characterisation of electrospun membranes: problems and improvements.
Colloids and surfaces. B, Biointerfaces 2009;71(1):1-12.
2009: D R Nisbet; David Moses; T R Gengenbach; John S Forsythe; David Finkelstein; Malcolm K Horne
Enhancing neurite outgrowth from primary neurones and neural stem cells using thermoresponsive hydrogel scaffolds for the repair of spinal cord injury.
Journal of biomedical materials research. Part A 2009;89(1):24-35.
2008: T D Aumann; Ilse Gantois; K Egan; A Vais; D Tomas; John Drago; Malcolm K Horne
SK channel function regulates the dopamine phenotype of neurons in the substantia nigra pars compacta.
Experimental neurology 2008;213(2):419-30.
2008: DR Nisbet; KE Crompton; Malcolm K Horne; David Finkelstein; John S Forsythe
Neural tissue engineering of the CNS using hydrogels.
Journal of biomedical materials research. Part B, Applied biomaterials 2008;87(1):251-63.
2008: Malcolm K Horne; Joohyung Lee; Feng Chen; Katherine Lanning; Doris Tomas; Andrew J Lawrence
Long-term administration of cocaine or serotonin reuptake inhibitors results in anatomical and neurochemical changes in noradrenergic, dopaminergic, and serotonin pathways.
Journal of neurochemistry 2008;106(4):1731-44.
2008: David Moses; John Drago; Yaroslav Teper; Ilse Gantois; David Finkelstein; Malcolm K Horne
Fetal striatum- and ventral mesencephalon-derived expanded neurospheres rescue dopaminergic neurons in vitro and the nigro-striatal system in vivo.
Neuroscience 2008;154(2):606-20.
2008: Joohyung Lee; Wen-Mei Zhu; Davor Stanic; David Finkelstein; Marjorie H Horne; Jasmine Henderson; Andrew J Lawrence; Louise O'Connor; Doris Tomas; John Drago; Malcolm K Horne
Sprouting of dopamine terminals and altered dopamine release and uptake in Parkinsonian dyskinaesia.
Brain : a journal of neurology 2008;131(Pt 6):1574-87.
2008: Julie D Atkin; Manal A Farg; Adam K Walker; Catriona McLean; Doris Tomas; Malcolm K Horne
Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis.
Neurobiology of disease 2008;30(3):400-7.
2007: Yaroslav Teper; Douglas Whyte; Elizabeth Cahir; Henry A Lester; Sharon R Grady; Michael J Marks; Bruce N Cohen; Carlos Fonck; Tristan McClure-Begley; J Michael McIntosh; Cesar Labarca; Andrew Lawrence; Feng Chen; Ilse Gantois; Philip J Davies; Steven Petrou; Mark Murphy; John Waddington; Malcolm K Horne; Samuel F Berkovic; John Drago
Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(38):10128-42.
2007: DR Nisbet; S Pattanawong; N E Ritchie; W Shen; David Finkelstein; Malcolm K Horne; John S Forsythe
Interaction of embryonic cortical neurons on nanofibrous scaffolds for neural tissue engineering.
Journal of neural engineering 2007;4(2):35-41.
2007: Yue Huang; Linda Truong; Himesha Vandebona; George D Mellick; Frank L Mastaglia; Julia Stevens; John B J Kwok; Michael Garlepp; Peter A Silburn; Malcolm K Horne; Katya Kotschet; Alison Venn; Dominic Rowe; Justin P Rubio; Carolyn M Sue
Prevalence and clinical features of common LRRK2 mutations in Australians with Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2007;22(7):982-9.
2007: Qiao-Xin Li; Su San Mok; Katrina M Laughton; Catriona A McLean; Roberto Cappai; Colin L Masters; Janetta G Culvenor; Malcolm K Horne
Plasma alpha-synuclein is decreased in subjects with Parkinson's disease.
Experimental neurology 2007;204(2):583-8.
2006: Julie D Atkin; Manal A Farg; Bradley J Turner; Doris Tomas; Judith A Lysaght; Janelle Nunan; Alan Rembach; Phillip Nagley; Philip M Beart; Surindar S Cheema; Malcolm K Horne
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.
The Journal of biological chemistry 2006;281(40):30152-65.
2006: Christopher A Reid; Harold A Coleman; David Finkelstein; Malcolm K Horne; John Drago
Null mutation of the alpha4 nicotinic receptor subunit increases the propensity of muscarinic-mediated neuronal bursting in mouse hippocampal slices.
Neuropharmacology 2006;51(3):587-96.
2006: DR Nisbet; S Pattanawong; Janelle Nunan; W Shen; Malcolm K Horne; David Finkelstein; John S Forsythe
The effect of surface hydrophilicity on the behavior of embryonic cortical neurons.
Journal of colloid and interface science 2006;299(2):647-55.
2006: David Moses; Yaroslav Teper; Ilse Gantois; David Finkelstein; Malcolm K Horne; John Drago
Murine embryonic EGF-responsive ventral mesencephalic neurospheres display distinct regional specification and promote survival of dopaminergic neurons.
Experimental neurology 2006;199(1):209-21.
2005: Clare L Parish; Janelle Nunan; David Finkelstein; Fergal N McNamara; J Y Wong; J L Waddington; R M Brown; Andrew J Lawrence; Malcolm K Horne; John Drago
Mice lacking the alpha4 nicotinic receptor subunit fail to modulate dopaminergic neuronal arbors and possess impaired dopamine transporter function.
Molecular pharmacology 2005;68(5):1376-86.
2005: Andrew J Lawrence; Clare L Parish; F Chen; Daniel J Lodge; EV Krstew; K Card; David Finkelstein; Malcolm K Horne
Chronic corticotropin-releasing factor type 1 receptor antagonism with antalarmin regulates the dopaminergic system of Fawn-Hooded rats.
Journal of neurochemistry 2005;94(6):1523-34.
2005: Clare L Parish; John Drago; Davor Stanic; E Borrelli; David Finkelstein; Malcolm K Horne
Haloperidol treatment reverses behavioural and anatomical changes in cocaine-dependent mice.
Neurobiology of disease 2005;19(1-2):301-11.
2005: Jasmine M Henderson; Davor Stanic; Doris Tomas; Justin Patch; Malcolm K Horne; Darren Bourke; David Finkelstein
Postural changes after lesions of the substantia nigra pars reticulata in hemiparkinsonian monkeys.
Behavioural brain research 2005;160(2):267-76.
2005: Jason J Ivanusic; Darren Bourke; Z M Xu; EG Butler; Malcolm K Horne
Cerebellar thalamic activity in the macaque monkey encodes the duration but not the force or velocity of wrist movement.
Brain research 2005;1041(2):181-97.
2005: Linda D Mercer; Belinda L Kelly; Malcolm K Horne; Philip M Beart
Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures.
Biochemical pharmacology 2005;69(2):339-45.
2004: Davor Stanic; Wanida Tripanichkul; John Drago; David Finkelstein; Malcolm K Horne
Glial responses associated with dopaminergic striatal reinnervation following lesions of the rat substantia nigra.
Brain research 2004;1023(1):83-91.
2004: David Finkelstein; Davor Stanic; Clare L Parish; John Drago; Malcolm K Horne
Quantified assessment of terminal density and innervation.
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] 2004;Chapter 1():Unit 1.13.
2004: Malcolm K Horne
The Monash University Consortium: factors involved in the local implementation of clinical evidence into practice.
The Medical journal of Australia 2004;180(10 Suppl):S89-91.
2003: Davor Stanic; David Finkelstein; Darren Bourke; John Drago; Malcolm K Horne
Timecourse of striatal re-innervation following lesions of dopaminergic SNpc neurons of the rat.
The European journal of neuroscience 2003;18(5):1175-88.
2003: John Y F Wong; Jeremiah J Clifford; Jim S Massalas; David Finkelstein; Malcolm K Horne; John L Waddington; John Drago
Neurochemical changes in dopamine D1, D3 and D1/D3 receptor knockout mice.
European journal of pharmacology 2003;472(1-2):39-47.
2003: John Drago; Craig McColl; Malcolm K Horne; David Finkelstein; S A Ross
Neuronal nicotinic receptors: insights gained from gene knockout and knockin mutant mice.
Cellular and molecular life sciences : CMLS 2003;60(7):1267-80.
2003: Davor Stanic; Clare L Parish; W M Zhu; EV Krstew; Andrew J Lawrence; John Drago; David Finkelstein; Malcolm K Horne
Changes in function and ultrastructure of striatal dopaminergic terminals that regenerate following partial lesions of the SNpc.
Journal of neurochemistry 2003;86(2):329-43.
2003: Wanida Tripanichkul; Davor Stanic; John Drago; David Finkelstein; Malcolm K Horne
D2 Dopamine receptor blockade results in sprouting of DA axons in the intact animal but prevents sprouting following nigral lesions.
The European journal of neuroscience 2003;17(5):1033-45.
2003: Craig McColl; Malcolm K Horne; David Finkelstein; John Y F Wong; Samuel F Berkovic; John Drago
Electroencephalographic characterisation of pentylenetetrazole-induced seizures in mice lacking the alpha 4 subunit of the neuronal nicotinic receptor.
Neuropharmacology 2003;44(2):234-43.
2002: Clare L Parish; David Finkelstein; Wanida Tripanichkul; Abhay R Satoskar; John Drago; Malcolm K Horne
The role of interleukin-1, interleukin-6, and glia in inducing growth of neuronal terminal arbors in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(18):8034-41.
2002: Clare L Parish; Davor Stanic; John Drago; E Borrelli; David Finkelstein; Malcolm K Horne
Effects of long-term treatment with dopamine receptor agonists and antagonists on terminal arbor size.
The European journal of neuroscience 2002;16(5):787-94.
2002: Patrick McManamny; Hun S Chy; David Finkelstein; Rebecca G Craythorn; Peter J Crack; Ismail Kola; Surindar S Cheema; Malcolm K Horne; Nigel G Wreford; Moira K O'Bryan; David M de Kretser; John R Morrison
A mouse model of spinal and bulbar muscular atrophy.
Human molecular genetics 2002;11(18):2103-11.
2002: John Y F Wong; Shelley A Ross; Craig McColl; Jim S Massalas; Emma Powney; David Finkelstein; Malcolm Clark; Malcolm K Horne; Samuel F Berkovic; John Drago
Proconvulsant-induced seizures in alpha(4) nicotinic acetylcholine receptor subunit knockout mice.
Neuropharmacology 2002;43(1):55-64.
2001: H T Kha; David Finkelstein; Doris Tomas; John Drago; David V Pow; Malcolm K Horne
Projections from the substantia nigra pars reticulata to the motor thalamus of the rat: single axon reconstructions and immunohistochemical study.
The Journal of comparative neurology 2001;440(1):20-30.
2001: Clare L Parish; David Finkelstein; John Drago; E Borrelli; Malcolm K Horne
The role of dopamine receptors in regulating the size of axonal arbors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(14):5147-57.
2000: H T Kha; David Finkelstein; David V Pow; A J Lawrence; Malcolm K Horne
Study of projections from the entopeduncular nucleus to the thalamus of the rat.
The Journal of comparative neurology 2000;426(3):366-77.
2000: S A Ross; John Y F Wong; Jeremiah J Clifford; A Kinsella; Jim S Massalas; Malcolm K Horne; I E Scheffer; I Kola; John L Waddington; Samuel F Berkovic; John Drago
Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(17):6431-41.
2000: EG Butler; Darren Bourke; Malcolm K Horne
The activity of primate ventrolateral thalamic neurones during motor adaptation.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2000;133(4):514-31.
2000: TD Aumann; S J Redman; Malcolm K Horne
Long-term potentiation across rat cerebello-thalamic synapses in vitro.
Neuroscience letters 2000;287(2):151-5.
2000: David Finkelstein; Davor Stanic; Clare L Parish; Doris Tomas; K Dickson; Malcolm K Horne
Axonal sprouting following lesions of the rat substantia nigra.
Neuroscience 2000;97(1):99-112.
1999: Z M Xu; Jason J Ivanusic; Darren Bourke; EG Butler; Malcolm K Horne
Automatic detection of bursts in spike trains recorded from the thalamus of a monkey performing wrist movements.
Journal of neuroscience methods 1999;91(1-2):123-33.
1999: TD Aumann; Malcolm K Horne
Ultrastructural change at rat cerebellothalamic synapses associated with volitional motor adaptation.
The Journal of comparative neurology 1999;409(1):71-84.
1998: FY Carroll; David Finkelstein; Malcolm K Horne; Andrew J Lawrence; Duncan Crawford; George Paxinos; Philip M Beart
Regional distribution of low affinity kainate receptors in brain of Macaca fascicularis determined by autoradiography using [3H](2S,4R)-4-methylglutamate.
Neuroscience letters 1998;255(2):71-4.
1998: TD Aumann; Jason J Ivanusic; Malcolm K Horne
Arborisation and termination of single motor thalamocortical axons in the rat.
The Journal of comparative neurology 1998;396(1):121-30.
1998: TD Aumann; John A Rawson; Malcolm K Horne
The relationship between monkey dentate cerebellar nucleus activity and kinematic parameters of wrist movement.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1998;119(2):179-90.
1998: EG Butler; M C Harvey; David Finkelstein; Malcolm K Horne
Neuronal activity in the monkey ventrolateral thalamus following perturbations of voluntary wrist movements.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1998;118(3):393-407.
1997: P R Churchward; EG Butler; David Finkelstein; TD Aumann; A Sudbury; Malcolm K Horne
A comparison of methods used to detect changes in neuronal discharge patterns.
Journal of neuroscience methods 1997;76(2):203-10.
1997: EG Butler; Darren Bourke; David Finkelstein; Malcolm K Horne
The effects of reversible inactivation of the subthalamo-pallidal pathway on the behaviour of naive and hemiparkinsonian monkeys.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 1997;4(2):218-27.
1996: TD Aumann; Malcolm K Horne
Ramification and termination of single axons in the cerebellothalamic pathway of the rat.
The Journal of comparative neurology 1996;376(3):420-30.
1996: L D Mercer; Philip M Beart; Malcolm K Horne; David Finkelstein; Pascal Carrive; George Paxinos
On the distribution of cholecystokinin B receptors in monkey brain.
Brain research 1996;738(2):313-8.
1996: EG Butler; David Finkelstein; M C Harvey; P R Churchward; L M Forlano; Malcolm K Horne
The relationship between monkey ventrolateral thalamic nucleus activity and kinematic parameters of wrist movement.
Brain research 1996;736(1-2):146-59.
1996: David Finkelstein; Perry F Bartlett; Malcolm K Horne; Surindar S Cheema
Leukemia inhibitory factor is a myotrophic and neurotrophic agent that enhances the reinnervation of muscle in the rat.
Journal of neuroscience research 1996;46(1):122-8.
1996: TD Aumann; Malcolm K Horne
A comparison of the ultrastructure of synapses in the cerebello-rubral and cerebello-thalamic pathways in the rat.
Neuroscience letters 1996;211(3):175-8.
1996: David Finkelstein; A K Reeves; Malcolm K Horne
An electron microscopic tracer study of the projections from entopeduncular nucleus to the ventrolateral nucleus of the rat.
Neuroscience letters 1996;211(1):33-6.
1996: TD Aumann; John A Rawson; C Pichitpornchai; Malcolm K Horne
Projections from the cerebellar interposed and dorsal column nuclei to the thalamus in the rat: a double anterograde labelling study.
The Journal of comparative neurology 1996;368(4):608-19.
1995: Malcolm K Horne; EG Butler
The role of the cerebello-thalamo-cortical pathway in skilled movement.
Progress in neurobiology 1995;46(2-3):199-213.
1994: TD Aumann; John A Rawson; David Finkelstein; Malcolm K Horne
Projections from the lateral and interposed cerebellar nuclei to the thalamus of the rat: a light and electron microscopic study using single and double anterograde labelling.
The Journal of comparative neurology 1994;349(2):165-81.
1993: L M Forlano; Malcolm K Horne; EG Butler; D Finkelstein
Neural activity in the monkey anterior ventrolateral thalamus during trained, ballistic movements.
Journal of neurophysiology 1993;70(6):2276-88.