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Seth Horne

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TOP 3
Karunakar Kar; Ravindra Kodali; Patrick C A van der Wel; Irene Arduini; Matthew A Baker; Kenneth W Drombosky; Cody L Hoop; W Seth Horne; Ronald Wetzel
β-hairpin-mediated nucleation of polyglutamine amyloid formation.
George A Lengyel; Geoffrey A Eddinger; W Seth Horne
Introduction of cyclically constrained γ-residues stabilizes an α-peptide hairpin in aqueous solution.
Kaylyn M Oshaben; Reza Salari; Lillian T Chong; Darrell R McCaslin; W Seth Horne
The native GCN4 leucine-zipper domain does not uniquely specify a dimeric oligomerization state.

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All Publications

2013: Karunakar Kar; Ravindra Kodali; Patrick C A van der Wel; Irene Arduini; Matthew A Baker; Kenneth W Drombosky; Cody L Hoop; W Seth Horne; Ronald Wetzel
β-hairpin-mediated nucleation of polyglutamine amyloid formation.
Journal of molecular biology 2013;425(7):1183-97.
2013: George A Lengyel; Geoffrey A Eddinger; W Seth Horne
Introduction of cyclically constrained γ-residues stabilizes an α-peptide hairpin in aqueous solution.
Organic letters 2013;15(4):944-7.
2012: Kaylyn M Oshaben; Reza Salari; Lillian T Chong; Darrell R McCaslin; W Seth Horne
The native GCN4 leucine-zipper domain does not uniquely specify a dimeric oligomerization state.
Biochemistry 2012;51(47):9581-91.
2012: George A Lengyel; W Seth Horne
Design strategies for the sequence-based mimicry of side-chain display in protein β-sheets by α/β-peptides.
Journal of the American Chemical Society 2012;134(38):15906-13.
2012: Timothy F Cunningham; W Seth Horne; Christopher Jaroniec; Marshall S McGoff; Ishita Sengupta; Sunil Saxena
High-resolution structure of a protein spin-label in a solvent-exposed β-sheet and comparison with DEER spectroscopy.
Biochemistry 2012;51(32):6350-9.
2012: Lisa M Johnson; Thomas J Ketas; Min Lu; John P Moore; David E Mortenson; Hyun Gi Yun; W Seth Horne; Samuel H Gellman
Enhancement of α-helix mimicry by an α/β-peptide foldamer via incorporation of a dense ionic side-chain array.
Journal of the American Chemical Society 2012;134(17):7317-20.
2011: W Seth Horne
Peptide and peptoid foldamers in medicinal chemistry.
Expert opinion on drug discovery 2011;6(12):1247-62.
2011: Lisa M Johnson; W Seth Horne; Samuel H Gellman
Broad distribution of energetically important contacts across an extended protein interface.
Journal of the American Chemical Society 2011;133(26):10038-41.
2010: Joshua L Price; W Seth Horne; Samuel H Gellman
Structural consequences of beta-amino acid preorganization in a self-assembling alpha/beta-peptide: fundamental studies of foldameric helix bundles.
Journal of the American Chemical Society 2010;132(35):12378-87.
2009: W Seth Horne; Lisa M Johnson; Thomas J Ketas; Per Johan Klasse; Min Lu; John P Moore; Samuel H Gellman
Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(35):14751-6.
2009: Michael W Giuliano; W Seth Horne; Samuel H Gellman
An alpha/beta-peptide helix bundle with a pure beta3-amino acid core and a distinctive quaternary structure.
Journal of the American Chemical Society 2009;131(29):9860-1.
2009: W Seth Horne; Christian A Olsen; John M Beierle; Ana Montero; M Reza Ghadiri
Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides.
Angewandte Chemie (International ed. in English) 2009;48(26):4718-24.
2009: John M Beierle; W Seth Horne; Jan H van Maarseveen; Beatrice Waser; Jean Claude Reubi; M Reza Ghadiri
Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues.
Angewandte Chemie (International ed. in English) 2009;48(26):4725-9.
2008: W Seth Horne; Samuel H Gellman
Foldamers with heterogeneous backbones.
Accounts of chemical research 2008;41(10):1399-408.
2008: W Seth Horne; Joshua L Price; Samuel H Gellman
Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(27):9151-6.
2008: W Seth Horne; Melissa D Boersma; Matthew A Windsor; Samuel H Gellman
Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains.
Angewandte Chemie (International ed. in English) 2008;47(15):2853-6.
2007: Joshua L Price; W Seth Horne; Samuel H Gellman
Discrete heterogeneous quaternary structure formed by alpha/beta-peptide foldamers and alpha-peptides.
Journal of the American Chemical Society 2007;129(20):6376-7.
2007: Yonggui Chi; Emily Payne English; William C Pomerantz; W Seth Horne; Leo A Joyce; Lane R Alexander; William S Fleming; Elizabeth A Hopkins; Samuel H Gellman
Practical synthesis of enantiomerically pure beta2-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes.
Journal of the American Chemical Society 2007;129(18):6050-5.
2007: W Seth Horne; Joshua L Price; James L Keck; Samuel H Gellman
Helix bundle quaternary structure from alpha/beta-peptide foldamers.
Journal of the American Chemical Society 2007;129(14):4178-80.
2006: Nurit Ashkenasy; W Seth Horne; M Reza Ghadiri
Design of self-assembling peptide nanotubes with delocalized electronic states.
Small (Weinheim an der Bergstrasse, Germany) 2006;2(1):99-102.
2005: Jan H van Maarseveen; W Seth Horne; M Reza Ghadiri
Efficient route to C2 symmetric heterocyclic backbone modified cyclic peptides.
Organic letters 2005;7(20):4503-6.
2005: W Seth Horne; Christopher M Wiethoff; Chunli Cui; Keith M Wilcoxen; Manuel Amorin; M Reza Ghadiri; Glen R Nemerow
Antiviral cyclic D,L-alpha-peptides: targeting a general biochemical pathway in virus infections.
Bioorganic & medicinal chemistry 2005;13(17):5145-53.
2005: W Seth Horne; Nurit Ashkenasy; M Reza Ghadiri
Modulating charge transfer through cyclic D,L-alpha-peptide self-assembly.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(4):1137-44.
2004: W Seth Horne; Maneesh K Yadav; C David Stout; M Reza Ghadiri
Heterocyclic peptide backbone modifications in an alpha-helical coiled coil.
Journal of the American Chemical Society 2004;126(47):15366-7.
2003: W Seth Horne; C David Stout; M Reza Ghadiri
A heterocyclic peptide nanotube.
Journal of the American Chemical Society 2003;125(31):9372-6.