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Michal Horowitz

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Nir Nesher; Eli Shapira; Daniel Sher; Liora Tsveyer; Ana Luiza Turchetti-Maia; Binyamin Hochner; Michal Horowitz; Yehu Moran; Eliahu Zlotkin
AdE-1, a new inotropic Na(+) channel toxin from Aiptasia diaphana, is similar to, yet distinct from, known anemone Na(+) channel toxins.
Gali Umschweif; Victoria Trembovler; Alexander Alexandrovich; Michal Horowitz; Esther Shohami
Hypoxia-inducible factor 1 is essential for spontaneous recovery from traumatic brain injury and is a key mediator of heat acclimation induced neuroprotection.
Miri Assayag; Haifa Canaana; Gary Gerstenblith; Ann Saada (Reisch); Rivka Shlomai; Michal Horowitz
Mitochondrial performance in heat acclimation--a lesson from ischemia/reperfusion and calcium overload insults in the heart.

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All Publications

2013: Nir Nesher; Eli Shapira; Daniel Sher; Liora Tsveyer; Ana Luiza Turchetti-Maia; Binyamin Hochner; Michal Horowitz; Yehu Moran; Eliahu Zlotkin
AdE-1, a new inotropic Na(+) channel toxin from Aiptasia diaphana, is similar to, yet distinct from, known anemone Na(+) channel toxins.
The Biochemical journal 2013;451(1):81-90.
2013: Gali Umschweif; Victoria Trembovler; Alexander Alexandrovich; Michal Horowitz; Esther Shohami
Hypoxia-inducible factor 1 is essential for spontaneous recovery from traumatic brain injury and is a key mediator of heat acclimation induced neuroprotection.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013;33(4):524-31.
2012: Miri Assayag; Haifa Canaana; Gary Gerstenblith; Ann Saada (Reisch); Rivka Shlomai; Michal Horowitz
Mitochondrial performance in heat acclimation--a lesson from ischemia/reperfusion and calcium overload insults in the heart.
American journal of physiology. Regulatory, integrative and comparative physiology 2012;303(8):R870-81.
2010: Michal Horowitz; Einat Kodesh
Molecular signals that shape the integrative responses of the heat-acclimated phenotype.
Medicine and science in sports and exercise 2010;42(12):2164-72.
2010: Miri Assayag; Gary Gerstenblith; Michael D Stern; Michal Horowitz
Long- but not short-term heat acclimation produces an apoptosis-resistant cardiac phenotype: a lesson from heat stress and ischemic/reperfusion insults.
Cell stress & chaperones 2010;15(5):651-64.
2010: Einat Kodesh; Michal Horowitz
Soleus adaptation to combined exercise and heat acclimation: physiogenomic aspects.
Medicine and science in sports and exercise 2010;42(5):943-52.
2010: Gali Umschwief; Na'ama A Shein; Alexander Alexandrovich; Victoria Trembovler; Michal Horowitz; Esther Shohami
Heat acclimation provides sustained improvement in functional recovery and attenuates apoptosis after traumatic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010;30(3):616-27.
2010: Ronen Durst; Kobi Goldstein; Yuval Horowitz; Aaron Baggish; Meir Gare; Yonathan Hasin; Chaim Lotan; Michal Horowitz
Hypothyroid dependent myocardial angiotensin receptor trafficking is involved in improved cardiac performance after heat acclimation.
Life sciences 2010;86(9-10):331-6.
2010: Michal Horowitz; Halla Assadi
Heat acclimation-mediated cross-tolerance in cardioprotection: do HSP70 and HIF-1alpha play a role?
Annals of the New York Academy of Sciences 2010;1188():199-206.
2010: Michal Horowitz
Genomics and proteomics of heat acclimation.
Frontiers in bioscience (Scholar edition) 2010;2():1068-80.
2008: Na'ama A Shein; Nikolaos Grigoriadis; Michal Horowitz; Gali Umschwief; Alexander Alexandrovich; Constantina Simeonidou; Savvas Grigoriadis; Olga Touloumi; Esther Shohami
Microglial involvement in neuroprotection following experimental traumatic brain injury in heat-acclimated mice.
Brain research 2008;1244():132-41.
2008: Anna Tetievsky; Omer Cohen; Luba Eli-Berchoer; Gary Gerstenblith; Michael D Stern; Ilan Wapinski; Nir Friedman; Michal Horowitz
Physiological and molecular evidence of heat acclimation memory: a lesson from thermal responses and ischemic cross-tolerance in the heart.
Physiological genomics 2008;34(1):78-87.
2008: Na'ama A Shein; Nikolaos Grigoriadis; Alexander Alexandrovich; Constantina Simeonidou; Evangelia Spandou; Jeanna Tsenter; Ido Yatsiv; Michal Horowitz; Esther Shohami
Differential neuroprotective properties of endogenous and exogenous erythropoietin in a mouse model of traumatic brain injury.
Journal of neurotrauma 2008;25(2):112-23.
2007: Na'ama A Shein; Hanny Doron; Michal Horowitz; Victoria Trembovler; Alexander Alexandrovich; Esther Shohami
Altered cytokine expression and sustained hypothermia following traumatic brain injury in heat acclimated mice.
Brain research 2007;1185():313-20.
2007: Na'ama A Shein; Jeanna Tsenter; Alexander Alexandrovich; Michal Horowitz; Esther Shohami
Akt phosphorylation is required for heat acclimation-induced neuroprotection.
Journal of neurochemistry 2007;103(4):1523-9.
2007: Omer Cohen; Hifa Kanana; Ronen Zoizner; Chaya Gross; Uri Meiri; Michael D Stern; Gary Gerstenblith; Michal Horowitz
Altered Ca2+ handling and myofilament desensitization underlie cardiomyocyte performance in normothermic and hyperthermic heat-acclimated rat hearts.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;103(1):266-75.
2007: Michal Horowitz; Sharon D M Robinson
Heat shock proteins and the heat shock response during hyperthermia and its modulation by altered physiological conditions.
Progress in brain research 2007;162():433-46.
2007: Michal Horowitz
Heat acclimation and cross-tolerance against novel stressors: genomic-physiological linkage.
Progress in brain research 2007;162():373-92.
2007: Na'ama A Shein; Michal Horowitz; Esther Shohami
Heat acclimation: a unique model of physiologically mediated global preconditioning against traumatic brain injury.
Progress in brain research 2007;161():353-63.
2006: Hagit Schwimmer; Luba Eli-Berchoer; Michal Horowitz
Acclimatory-phase specificity of gene expression during the course of heat acclimation and superimposed hypohydration in the rat hypothalamus.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;100(6):1992-2003.
2006: Daniel S Moran; Luba Eli-Berchoer; Yuval Heled; Liran Mendel; Mara Schocina; Michal Horowitz
Heat intolerance: does gene transcription contribute?
Journal of applied physiology (Bethesda, Md. : 1985) 2006;100(4):1370-6.
2006: Garry Milman; Yehoshua Maor; Saleh Abu-Lafi; Michal Horowitz; Ruth Gallily; Sandor Batkai; Fong-Ming Mo; Laszlo Offertaler; Pal Pacher; George Kunos; Urij Rampampam
N-arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2428-33.
2005: Na'ama A Shein; Michal Horowitz; Alexander Alexandrovich; Jeanna Tsenter; Esther Shohami
Heat acclimation increases hypoxia-inducible factor 1alpha and erythropoietin receptor expression: implication for neuroprotection after closed head injury in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(11):1456-65.
2005: Alina Maloyan; Luba Eli-Berchoer; Gregg L Semenza; Gary Gerstenblith; Michael D Stern; Michal Horowitz
HIF-1alpha-targeted pathways are activated by heat acclimation and contribute to acclimation-ischemic cross-tolerance in the heart.
Physiological genomics 2005;23(1):79-88.
2004: Hagit Schwimmer; R Gerstberger; Michal Horowitz
Heat acclimation affects the neuromodulatory role of AngII and nitric oxide during combined heat and hypohydration stress.
Brain research. Molecular brain research 2004;130(1-2):95-108.
2004: Ziv Paz; Sharon Freeman; Michal Horowitz; Haim Sohmer
Prior heat acclimation confers protection against noise-induced hearing loss.
Audiology & neuro-otology 2004;9(6):363-9.
2004: Michal Horowitz; Luba Eli-Berchoer; Ilan Wapinski; Nir Friedman; Einat Kodesh
Stress-related genomic responses during the course of heat acclimation and its association with ischemic-reperfusion cross-tolerance.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;97(4):1496-507.
2004: Hagit Schwimmer; R Gerstberger; Michal Horowitz
Nitric oxide and angiotensin II: neuromodulation of thermoregulation during combined heat and hypohydration stress.
Brain research 2004;1006(2):177-89.
2003: Michal Horowitz
Matching the heart to heat-induced circulatory load: heat-acclimatory responses.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2003;18():215-21.
2002: Mirit Eynan; Tanya Knubuvetz; Uri Meiri; Gil Navon; Gary Gerstenblith; Zohar Bromberg; Yonathan Hasin; Michal Horowitz
Heat acclimation-induced elevated glycogen, glycolysis, and low thyroxine improve heart ischemic tolerance.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;93(6):2095-104.
2002: Eshel Ophir; Yehuda Arieli; Jacob Marder; Michal Horowitz
Cutaneous blood flow in the pigeon Columba livia: its possible relevance to cutaneous water evaporation.
The Journal of experimental biology 2002;205(Pt 17):2627-36.
2002: Hilary Shmeeda; Pavel Kaspler; Judith Shleyer; Reuma Honen; Michal Horowitz; Yechezkel Barenholz
Heat acclimation in rats: modulation via lipid polyunsaturation.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;283(2):R389-99.
2002: Alina Maloyan; Michal Horowitz
beta-Adrenergic signaling and thyroid hormones affect HSP72 expression during heat acclimation.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;93(1):107-15.
2002: Michal Horowitz
From molecular and cellular to integrative heat defense during exposure to chronic heat.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2002;131(3):475-83.
2001: Pavel Kaspler; Michal Horowitz
Heat acclimation and heat stress have different effects on cholinergic-induced calcium mobilization.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(6):R1688-96.
2000: E Mirit; C Gross; Yonathan Hasin; Aaron Palmon; Michal Horowitz
Changes in cardiac mechanics with heat acclimation: adrenergic signaling and SR-Ca regulatory proteins.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(1):R77-85.
1999: Lumír O Hanus; Aviva Breuer; Susanna Tchilibon; S Shiloah; D Goldenberg; Michal Horowitz; R G Pertwee; R A Ross; Urij Rampampam; Ester Fride
HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14228-33.
1999: Yehuda Arieli; N Feinstein; Pnina Raber; Michal Horowitz; Jacob Marder
Heat stress induces ultrastructural changes in cutaneous capillary wall of heat-acclimated rock pigeon.
The American journal of physiology 1999;277(4 Pt 2):R967-74.
1999: Victoria Trembovler; Elie Beit-Yannai; F Younis; Ruth Gallily; Michal Horowitz; Esther Shohami
Antioxidants attenuate acute toxicity of tumor necrosis factor-alpha induced by brain injury in rat.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999;19(7):791-5.
1999: Michal Horowitz; Pavel Kaspler; E Simon; R Gerstberger
Heat acclimation and hypohydration: involvement of central angiotensin II receptors in thermoregulation.
The American journal of physiology 1999;277(1 Pt 2):R47-55.
1999: Alina Maloyan; Aaron Palmon; Michal Horowitz
Heat acclimation increases the basal HSP72 level and alters its production dynamics during heat stress.
The American journal of physiology 1999;276(5 Pt 2):R1506-15.
1999: E Mirit; Aaron Palmon; Yonathan Hasin; Michal Horowitz
Heat acclimation induces changes in cardiac mechanical performance: the role of thyroid hormone.
The American journal of physiology 1999;276(2 Pt 2):R550-8.
1999: Pavel Kaspler; A Moran; Michal Horowitz
Effect of heat acclimation and heat shock on oscillations of carbamyl-choline-evoked Ca2+ signal in HSY cell line.
Journal of basic and clinical physiology and pharmacology 1999;10(2):153-61.
1998: Elie Beit-Yannai; Victoria Trembovler; Michal Horowitz; Philip Lazarovici; Ron Kohen; Esther Shohami
Neuroprotection against oxidative stress by serum from heat acclimated rats.
Neuroscience letters 1998;254(2):89-92.
1997: Esther Shohami; Elie Beit-Yannai; Michal Horowitz; Ron Kohen
Oxidative stress in closed-head injury: brain antioxidant capacity as an indicator of functional outcome.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(10):1007-19.
1997: E Levy; Yonathan Hasin; G Navon; Michal Horowitz
Chronic heat improves mechanical and metabolic response of trained rat heart on ischemia and reperfusion.
The American journal of physiology 1997;272(5 Pt 2):H2085-94.
1997: Pavel Kaspler; Michal Horowitz
Heat acclimation and heat stress have different effects on cholinergic muscarinic receptors.
Annals of the New York Academy of Sciences 1997;813():620-7.
1997: Michal Horowitz; Alina Maloyan; J Shlaier
HSP 70 kDa dynamics in animals undergoing heat stress superimposed on heat acclimation.
Annals of the New York Academy of Sciences 1997;813():617-9.
1997: Elie Beit-Yannai; Ron Kohen; Michal Horowitz; Victoria Trembovler; Esther Shohami
Changes of biological reducing activity in rat brain following closed head injury: a cyclic voltammetry study in normal and heat-acclimated rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(3):273-9.
1996: Michal Horowitz; Pavel Kaspler; Yitzhak Marmary; Yoram Oron
Evidence for contribution of effector organ cellular responses to the biphasic dynamics of heat acclimation.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;80(1):77-85.
1994: Esther Shohami; M Novikov; Michal Horowitz
Long term exposure to heat protects against brain damage induced by closed head injury in the rat.
Restorative neurology and neuroscience 1994;6(2):107-12.
1994: Esther Shohami; M Novikov; Michal Horowitz
Long term exposure to heat reduces edema formation after closed head injury in the rat.
Acta neurochirurgica. Supplementum 1994;60():443-5.
1993: M M Krausz; Amiram Ravid; U Izhar; E Feigin; Michal Horowitz; D Gross
The effect of heat load and dehydration on hypertonic saline solution treatment of controlled hemorrhagic shock.
Surgery, gynecology & obstetrics 1993;177(6):583-92.
1993: E Levi; Antonio Vivi; Yonathan Hasin; Maria Tassini; Gil Navon; Michal Horowitz
Heat acclimation improves cardiac mechanics and metabolic performance during ischemia and reperfusion.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(2):833-9.
1993: Michal Horowitz; U Meiri
Mechanism of heat acclimation induced bradycardia in the sand rat.
Journal of basic and clinical physiology and pharmacology 1993;4(1-2):37-46.
1993: Michal Horowitz; S Parnes; Yonathan Hasin
Mechanical and metabolic performance of the rat heart: effects of combined stress of heat acclimation and swimming training.
Journal of basic and clinical physiology and pharmacology 1993;4(1-2):139-56.
1993: Michal Horowitz; U Meiri
Central and peripheral contributions to control of heart rate during heat acclimation.
Pflügers Archiv : European journal of physiology 1993;422(4):386-92.
1991: Y Zurovski; L Eckstein; Michal Horowitz
Heat stress and thermal dehydration: lactacidemia and plasma volume regulation.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;71(6):2434-9.
1990: Michal Horowitz
Thermoregulation under conditions of impaired body fluid/osmotic balance in mammals.
Journal of basic and clinical physiology and pharmacology 1990;1(1-4):267-76.
1989: Yoram Oron; O Falach; I Marmary; Michal Horowitz
Long-term heat adaptation results in an enhanced efficiency of muscarinically-induced water secretion in rat submaxillary glands.
Comparative biochemistry and physiology. A, Comparative physiology 1989;94(4):673-6.
1988: Michal Horowitz; S Samueloff
Cardiac output distribution in thermally dehydrated rodents.
The American journal of physiology 1988;254(1 Pt 2):R109-16.