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Stuart Horowitz

Research Profile

Anatomy

Chemicals & Drugs

Disorders

Hyperoxia

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Publications

TOP 3
John Romashko; Stuart Horowitz; William R Franek; Thomas Palaia; Edmund Miller; Anning Lin; Michael J Birrer; William Scott; Lin L Mantell
MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells.
William R Franek; Yalamanchali C Chowdary; Xinchun Lin; Maowen Hu; Edmund Miller; Jeffrey A Kazzaz; Pasquale Razzano; John Romashko; Jonathan M Davis; Pramod Narula; Stuart Horowitz; William Scott; Lin L Mantell
Suppression of nuclear factor-kappa B activity by nitric oxide and hyperoxia in oxygen-resistant cells.
Lin L Mantell; Thomas H Shaffer; Stuart Horowitz; Ray Foust; Marla R Wolfson; Cindy Cox; Poonam Khullar; Zahra Zakeri; Lin Lin; Jeffrey A Kazzaz; Thomas Palaia; William Scott; Jonathan M Davis
Distinct patterns of apoptosis in the lung during liquid ventilation compared with gas ventilation.

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All Publications

2003: John Romashko; Stuart Horowitz; William R Franek; Thomas Palaia; Edmund Miller; Anning Lin; Michael J Birrer; William Scott; Lin L Mantell
MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells.
Free radical biology & medicine 2003;35(8):978-93.
2002: William R Franek; Yalamanchali C Chowdary; Xinchun Lin; Maowen Hu; Edmund Miller; Jeffrey A Kazzaz; Pasquale Razzano; John Romashko; Jonathan M Davis; Pramod Narula; Stuart Horowitz; William Scott; Lin L Mantell
Suppression of nuclear factor-kappa B activity by nitric oxide and hyperoxia in oxygen-resistant cells.
The Journal of biological chemistry 2002;277(45):42694-700.
2002: Lin L Mantell; Thomas H Shaffer; Stuart Horowitz; Ray Foust; Marla R Wolfson; Cindy Cox; Poonam Khullar; Zahra Zakeri; Lin Lin; Jeffrey A Kazzaz; Thomas Palaia; William Scott; Jonathan M Davis
Distinct patterns of apoptosis in the lung during liquid ventilation compared with gas ventilation.
American journal of physiology. Lung cellular and molecular physiology 2002;283(1):L31-41.
2001: A M Ilizarov; Hshi-Chi Koo; Jeffrey A Kazzaz; Lin L Mantell; Yuchi Li; R Bhapat; Simcha Pollack; Stuart Horowitz; Jonathan M Davis
Overexpression of manganese superoxide dismutase protects lung epithelial cells against oxidant injury.
American journal of respiratory cell and molecular biology 2001;24(4):436-41.
2001: William R Franek; Stuart Horowitz; L Stansberry; Jeffrey A Kazzaz; Hshi-Chi Koo; Yuchi Li; Yuko Arita; Jonathan M Davis; A S Mantell; William Scott; Lin L Mantell
Hyperoxia inhibits oxidant-induced apoptosis in lung epithelial cells.
The Journal of biological chemistry 2001;276(1):569-75.
2000: Jeffrey A Kazzaz; Stuart Horowitz; J Xu; P Khullar; Michael S Niederman; A M Fein; Zahra Zakeri; L Lin; G C Rhodes
Differential patterns of apoptosis in resolving and nonresolving bacterial pneumonia.
American journal of respiratory and critical care medicine 2000;161(6):2043-50.
1999: Irina Petrache; Mary E Choi; Leo E Otterbein; Beek Yoke Chin; Lin L Mantell; Stuart Horowitz; Augustine M K Choi
Mitogen-activated protein kinase pathway mediates hyperoxia-induced apoptosis in cultured macrophage cells.
The American journal of physiology 1999;277(3 Pt 1):L589-95.
1999: Lin L Mantell; Stuart Horowitz; Jonathan M Davis; Jeffrey A Kazzaz
Hyperoxia-induced cell death in the lung--the correlation of apoptosis, necrosis, and inflammation.
Annals of the New York Academy of Sciences 1999;887():171-80.
1999: Jeffrey A Kazzaz; Stuart Horowitz; Y Li; Lin L Mantell
Hyperoxia in cell culture. A non-apoptotic programmed cell death.
Annals of the New York Academy of Sciences 1999;887():164-70.
1998: Bruno Piedboeuf; M Gamache; J Frenette; Stuart Horowitz; H S Baldwin; Peter Petrov
Increased endothelial cell expression of platelet-endothelial cell adhesion molecule-1 during hyperoxic lung injury.
American journal of respiratory cell and molecular biology 1998;19(4):543-53.
1998: Leo E Otterbein; Beek Yoke Chin; Lin L Mantell; L Stansberry; Stuart Horowitz; Augustine M K Choi
Pulmonary apoptosis in aged and oxygen-tolerant rats exposed to hyperoxia.
The American journal of physiology 1998;275(1 Pt 1):L14-20.
1998: Bruno Piedboeuf; Stuart Horowitz; C J Johnston; M Gamache; Sylvie Bélanger; P E Poubelle; Stephen E Welty; Richard H Watkins
Interleukin-1 expression during hyperoxic lung injury in the mouse.
Free radical biology & medicine 1998;24(9):1446-54.
1998: S Das; Stuart Horowitz; CG Robbins; M E el-Sabban; N Sahgal; Jonathan M Davis
Intracellular uptake of recombinant superoxide dismutase after intratracheal administration.
The American journal of physiology 1998;274(5 Pt 1):L673-7.
1998: William M Maniscalco; Richard H Watkins; Patricia R Chess; Robert Sinkin; Stuart Horowitz; Liana Toia
Cell-specific expression of fibronectin and EIIIA and EIIIB splice variants after oxygen injury.
The American journal of physiology 1998;274(4 Pt 1):L599-609.
1998: Pramod Narula; J Xu; Jeffrey A Kazzaz; CG Robbins; Jonathan M Davis; Stuart Horowitz
Synergistic cytotoxicity from nitric oxide and hyperoxia in cultured lung cells.
The American journal of physiology 1998;274(3 Pt 1):L411-6.
1997: Lin L Mantell; Jeffrey A Kazzaz; J Xu; Thomas Palaia; Bruno Piedboeuf; Stephen B Hall; G C Rhodes; G Niu; A F Fein; Stuart Horowitz
Unscheduled apoptosis during acute inflammatory lung injury.
Cell death and differentiation 1997;4(7):600-7.
1997: Yuchi Li; Wenyi Zhang; Lin L Mantell; Jeffrey A Kazzaz; A M Fein; Stuart Horowitz
Nuclear factor-kappaB is activated by hyperoxia but does not protect from cell death.
The Journal of biological chemistry 1997;272(33):20646-9.
1997: Jonathan M Davis; WN Rosenfeld; S E Richter; M R Parad; Ira H Gewolb; Alan Spitzer; W A Carlo; R J Couser; A Price; ER Flaster; N Kassem; L Edwards; J Tierney; Stuart Horowitz
Safety and pharmacokinetics of multiple doses of recombinant human CuZn superoxide dismutase administered intratracheally to premature neonates with respiratory distress syndrome.
Pediatrics 1997;100(1):24-30.
1997: CG Robbins; Stuart Horowitz; T Allen Merritt; A Kheiter; J Tierney; Pramod Narula; Jonathan M Davis
Recombinant human superoxide dismutase reduces lung injury caused by inhaled nitric oxide and hyperoxia.
The American journal of physiology 1997;272(5 Pt 1):L903-7.
1996: N Sahgal; Jonathan M Davis; C Robbins; Stuart Horowitz; E G Langenback; R H Perry; D Colflesh; J Tierney; S R Simon
Localization and activity of recombinant human CuZn superoxide dismutase after intratracheal administration.
The American journal of physiology 1996;271(2 Pt 1):L230-5.
1996: Bruno Piedboeuf; J Frenette; P Petrov; Stephen E Welty; Jeffrey A Kazzaz; Stuart Horowitz
In vivo expression of intercellular adhesion molecule 1 in type II pneumocytes during hyperoxia.
American journal of respiratory cell and molecular biology 1996;15(1):71-7.
1996: Jeffrey A Kazzaz; J Xu; Thomas Palaia; Lin L Mantell; A M Fein; Stuart Horowitz
Cellular oxygen toxicity. Oxidant injury without apoptosis.
The Journal of biological chemistry 1996;271(25):15182-6.
1996: Nelly E Avissar; Jacob N Finkelstein; Stuart Horowitz; James Willey; E Coy; M W Frampton; Richard H Watkins; P Khullar; Y L Xu; Harvey Jay Cohen
Extracellular glutathione peroxidase in human lung epithelial lining fluid and in lung cells.
The American journal of physiology 1996;270(2 Pt 1):L173-82.
1995: C G Robbins; Jonathan M Davis; T A Merritt; J D Amirkhanian; N Sahgal; F C Morin; Stuart Horowitz
Combined effects of nitric oxide and hyperoxia on surfactant function and pulmonary inflammation.
The American journal of physiology 1995;269(4 Pt 1):L545-50.
1995: Jonathan M Davis; C G Robbins; T Anderson; N Sahgal; L Genen; J Tierney; Stuart Horowitz
The effects of hyperoxia, mechanical ventilation, and dexamethasone on pulmonary antioxidant enzyme activity in the newborn piglet.
Pediatric pulmonology 1995;20(2):107-11.
1995: Robert Sinkin; R S Sanders; Stuart Horowitz; Jacob N Finkelstein; Michael B LoMonaco
Cell-specific expression of fibronectin in adult and developing rabbit lung.
Pediatric research 1995;37(2):189-95.
1994: Nelly E Avissar; C Eisenmann; J G Breen; Stuart Horowitz; Richard Miller; Harvey Jay Cohen
Human placenta makes extracellular glutathione peroxidase and secretes it into maternal circulation.
The American journal of physiology 1994;267(1 Pt 1):E68-76.
1994: J G Breen; C Eisenmann; Stuart Horowitz; Rita K Miller
Cell-specific increases in metallothionein expression in the human placenta perfused with cadmium.
Reproductive toxicology (Elmsford, N.Y.) 1994;8(4):297-306.
1994: Bruno Piedboeuf; William M Maniscalco; Stephen B Hall; M Campbell; R Watkins; Stuart Horowitz
In vivo and in vitro expression of metallothionein in injured type II alveolar epithelial cells.
Chest 1994;105(3 Suppl):78S.
1994: Nelly E Avissar; D B Ornt; Y Yagil; Stuart Horowitz; Richard H Watkins; E A Kerl; K Takahashi; I S Palmer; Harvey Jay Cohen
Human kidney proximal tubules are the main source of plasma glutathione peroxidase.
The American journal of physiology 1994;266(2 Pt 1):C367-75.
1994: Bruno Piedboeuf; Carl J Johnston; Richard H Watkins; B B Hudak; John Lazo; M G Cherian; Stuart Horowitz
Increased expression of tissue inhibitor of metalloproteinases (TIMP-I) and metallothionein in murine lungs after hyperoxic exposure.
American journal of respiratory cell and molecular biology 1994;10(2):123-32.
1992: Robert Sinkin; Michael B LoMonaco; Jacob N Finkelstein; Richard H Watkins; Christopher Cox; Stuart Horowitz
Increased fibronectin mRNA in alveolar macrophages following in vivo hyperoxia.
American journal of respiratory cell and molecular biology 1992;7(5):548-55.
1991: Kathleen A Veness-Meehan; E R Cheng; C E Mercier; S L Blixt; Carl J Johnston; Richard H Watkins; Stuart Horowitz
Cell-specific alterations in expression of hyperoxia-induced mRNAs of lung.
American journal of respiratory cell and molecular biology 1991;5(6):516-21.
1991: Stuart Horowitz; Richard H Watkins; R L Auten; C E Mercier; E R Cheng
Differential accumulation of surfactant protein A, B, and C mRNAs in two epithelial cell types of hyperoxic lung.
American journal of respiratory cell and molecular biology 1991;5(6):511-5.
1990: R L Auten; Richard H Watkins; D L Shapiro; Stuart Horowitz
Surfactant apoprotein A (SP-A) is synthesized in airway cells.
American journal of respiratory cell and molecular biology 1990;3(5):491-6.
1990: Stuart Horowitz; D L Shapiro; Jacob N Finkelstein; Robert H Notter; Carl J Johnston; D J Quible
Changes in gene expression in hyperoxia-induced neonatal lung injury.
The American journal of physiology 1990;258(2 Pt 1):L107-11.
1989: Stuart Horowitz; N Dafni; D L Shapiro; B A Holm; Robert H Notter; D J Quible
Hyperoxic exposure alters gene expression in the lung. Induction of the tissue inhibitor of metalloproteinases mRNA and other mRNAs.
The Journal of biological chemistry 1989;264(13):7092-5.