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Lloyd Horrocks
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Chemicals & Drugs
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58
Farooqui, Akhlaq
16
Murphy, Eric
7
Farooqui, Tahira
6
Rosenberger, Thad
6
Ong, Wei-Yi
5
Ong, Wei-Yi
4
Lu, Xin-Rong
4
Antony, Pierre
4
Freysz, Louis
2
Halliwell, Barry
2
Bates, Carlton
2
Altschuld, Ruth
2
Litsky, Monica
2
Yates, Allan
2
Roberts, Eugene
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All Publications
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2007: Farooqui Akhlaq A; Ong Wei-Yi; Horrocks Lloyd A; Chen Peng; Farooqui Tahira
Comparison of biochemical effects of statins and fish oil in brain: the battle of the titans.
Brain research reviews 2007;56(2):443-71.
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2007: Sun Grace Y; Horrocks Lloyd A; Farooqui Akhlaq A
The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases.
Journal of neurochemistry 2007;103(1):1-16.
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2007: Farooqui Akhlaq A; Horrocks Lloyd A; Farooqui Tahira
Interactions between neural membrane glycerophospholipid and sphingolipid mediators: a recipe for neural cell survival or suicide.
Journal of neuroscience research 2007;85(9):1834-50.
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2007: Farooqui Akhlaq A; Horrocks Lloyd A; Farooqui Tahira
Modulation of inflammation in brain: a matter of fat.
Journal of neurochemistry 2007;101(3):577-99.
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2007: Rosenberger Thad A; Farooqui Akhlaq A; Horrocks Lloyd A
Bovine brain diacylglycerol lipase: substrate specificity and activation by cyclic AMP-dependent protein kinase.
Lipids 2007;42(3):187-95.
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2006: Farooqui Akhlaq A; Ong Wei-Yi; Horrocks Lloyd A
Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders.
Pharmacological reviews 2006;58(3):591-620.
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2006: Phillis John W; Horrocks Lloyd A; Farooqui Akhlaq A
Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: their role and involvement in neurological disorders.
Brain research reviews 2006;52(2):201-43.
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2006: Farooqui Akhlaq A; Horrocks Lloyd A
Phospholipase A2-generated lipid mediators in the brain: the good, the bad, and the ugly.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2006;12(3):245-60.
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2005: Farooqui Akhlaq A; Horrocks Lloyd A
Signaling and interplay mediated by phospholipases A2, C, and D in LA-N-1 cell nuclei.
Reproduction, nutrition, development 2005;45(5):613-31.
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2004: Farooqui Akhlaq A; Ong Wei-Yi; Horrocks Lloyd A
Biochemical aspects of neurodegeneration in human brain: involvement of neural membrane phospholipids and phospholipases A2.
Neurochemical research 2004;29(11):1961-77.
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2004: Farooqui Akhlaq A; Horrocks Lloyd A
Brain phospholipases A2: a perspective on the history.
Prostaglandins, leukotrienes, and essential fatty acids 2004;71(3):161-9.
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2004: Farooqui Akhlaq A; Antony Pierre; Ong Wei-Yi; Horrocks Lloyd A; Freysz Louis
Retinoic acid-mediated phospholipase A2 signaling in the nucleus.
Brain research. Brain research reviews 2004;45(3):179-95.
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2004: Horrocks Lloyd A; Farooqui Akhlaq A
Docosahexaenoic acid in the diet: its importance in maintenance and restoration of neural membrane function.
Prostaglandins, leukotrienes, and essential fatty acids 2004;70(4):361-72.
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2004: Farooqui Akhlaq A; Ong Wei-Yi; Horrocks Lloyd A
Neuroprotection abilities of cytosolic phospholipase A2 inhibitors in kainic acid-induced neurodegeneration.
Current drug targets. Cardiovascular & haematological disorders 2004;4(1):85-96.
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2003: Ong Wei-Yi; Lu Xin-Rong; Horrocks Lloyd A; Farooqui A A; Garey Laurence J
Induction of astrocytic cytoplasmic phospholipase A2 and neuronal death after intracerebroventricular carrageenan injection, and neuroprotective effects of quinacrine.
Experimental neurology 2003;183(2):449-57.
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2003: Antony Pierre; Freysz Louis; Horrocks Lloyd A; Farooqui Akhlaq A
Ca2+-independent phospholipases A2 and production of arachidonic acid in nuclei of LA-N-1 cell cultures: a specific receptor activation mediated with retinoic acid.
Brain research. Molecular brain research 2003;115(2):187-95.
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2003: Ong Wei-Yi; Lu Xin-Rong; Ong Benjamin Kian-Chung; Horrocks Lloyd A; Farooqui Akhlaq A; Lim Sai-Kiang
Quinacrine abolishes increases in cytoplasmic phospholipase A2 mRNA levels in the rat hippocampus after kainate-induced neuronal injury.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2003;148(4):521-4.
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2003: Farooqui Akhlaq A; Ong Wei-Yi; Horrocks Lloyd A
Plasmalogens, docosahexaenoic acid and neurological disorders.
Advances in experimental medicine and biology 2003;544():335-54.
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2001: Farooqui A A; Yi Ong W; Lu X R; Halliwell B; Horrocks L A
Neurochemical consequences of kainate-induced toxicity in brain: involvement of arachidonic acid release and prevention of toxicity by phospholipase A(2) inhibitors.
Brain research. Brain research reviews 2001;38(1-2):61-78.
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2001: Antony P; Farooqui A A; Horrocks L A; Freysz L
Effect of D609 on phosphatidylcholine metabolism in the nuclei of LA-N-1 neuroblastoma cells: a key role for diacylglycerol.
FEBS letters 2001;509(1):115-8.
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2001: Farooqui A A; Horrocks L A
Plasmalogens: workhorse lipids of membranes in normal and injured neurons and glia.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2001;7(3):232-45.
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2001: Lu X R; Ong W Y; Halliwell B; Horrocks L A; Farooqui A A
Differential effects of calcium-dependent and calcium-independent phospholipase A(2) inhibitors on kainate-induced neuronal injury in rat hippocampal slices.
Free radical biology & medicine 2001;30(11):1263-73.
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2001: Farooqu A A; Horrocks L A
Plasmalogens, phospholipase A2, and docosahexaenoic acid turnover in brain tissue.
Journal of molecular neuroscience : MN 2001;16(2-3):263-72; discussion 279-84.
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2001: Antony P; Freysz L; Horrocks L A; Farooqui A A
Effect of retinoic acid on the Ca2+-independent phospholipase A2 in nuclei of LA-N-1 neuroblastoma cells.
Neurochemical research 2001;26(1):83-8.
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2000: Farooqui A A; Horrocks L A; Farooqui T
Deacylation and reacylation of neural membrane glycerophospholipids.
Journal of molecular neuroscience : MN 2000;14(3):123-35.
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2000: Farooqui A A; Horrocks L A; Farooqui T
Glycerophospholipids in brain: their metabolism, incorporation into membranes, functions, and involvement in neurological disorders.
Chemistry and physics of lipids 2000;106(1):1-29.
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1999: Farooqui A A; Litsky M L; Farooqui T; Horrocks L A
Inhibitors of intracellular phospholipase A2 activity: their neurochemical effects and therapeutical importance for neurological disorders.
Brain research bulletin 1999;49(3):139-53.
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1999: Ong W Y; Horrocks L A; Farooqui A A
Immunocytochemical localization of cPLA2 in rat and monkey spinal cord.
Journal of molecular neuroscience : MN 1999;12(2):123-30.
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1999: Jurkowitz M S; Horrocks L A; Litsky M L
Identification and characterization of alkenyl hydrolase (lysoplasmalogenase) in microsomes and identification of a plasmalogen-active phospholipase A2 in cytosol of small intestinal epithelium.
Biochimica et biophysica acta 1999;1437(2):142-56.
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1999: Ong W Y; Sandhya T L; Horrocks L A; Farooqui A A
Distribution of cytoplasmic phospholipase A2 in the normal rat brain.
Journal für Hirnforschung 1999;39(3):391-400.
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1999: Farooqui A A; Horrocks L A
Purification of lipases and phospholipases by heparin-sepharose chromatography.
Methods in molecular biology (Clifton, N.J.) 1999;109():133-43.
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1999: Farooqui A A; Yang H C; Hirashima Y; Horrocks L A
Determination of plasmalogen-selective phospholipase A2 activity by radiochemical and fluorometric assay procedures.
Methods in molecular biology (Clifton, N.J.) 1999;109():39-47.
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1998: Farooqui A A; Horrocks L A
Lipid peroxides in the free radical pathophysiology of brain diseases.
Cellular and molecular neurobiology 1998;18(6):599-608.
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1998: Farooqui A A; Horrocks L A
Plasmalogen-selective phospholipase A2 and its involvement in Alzheimer's disease.
Biochemical Society transactions 1998;26(2):243-6.
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1998: Sandhya T L; Ong W Y; Horrocks L A; Farooqui A A
A light and electron microscopic study of cytoplasmic phospholipase A2 and cyclooxygenase-2 in the hippocampus after kainate lesions.
Brain research 1998;788(1-2):223-31.
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1997: Farooqui A A; Horrocks L A
Nitric oxide synthase inhibitors do not attenuate diacylglycerol or monoacylglycerol lipase activities in synaptoneurosomes.
Neurochemical research 1997;22(10):1265-9.
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1997: Murphy E J; Rosenberger T A; Horrocks L A
Effects of maturation on the phospholipid and phospholipid fatty acid compositions in primary rat cortical astrocyte cell cultures.
Neurochemical research 1997;22(10):1205-13.
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1997: Farooqui A A; Yang H C; Rosenberger T A; Horrocks L A
Phospholipase A2 and its role in brain tissue.
Journal of neurochemistry 1997;69(3):889-901.
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1997: Farooqui A A; Yang H C; Horrocks L
Involvement of phospholipase A2 in neurodegeneration.
Neurochemistry international 1997;30(6):517-22.
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1997: Farooqui A A; Rapoport S I; Horrocks L A
Membrane phospholipid alterations in Alzheimer's disease: deficiency of ethanolamine plasmalogens.
Neurochemical research 1997;22(4):523-7.
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1996: Haun S E; Segeleon J E; Trapp V L; Clotz M A; Horrocks L A
Inosine mediates the protective effect of adenosine in rat astrocyte cultures subjected to combined glucose-oxygen deprivation.
Journal of neurochemistry 1996;67(5):2051-9.
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1996: Murphy E J; Rosenberger T A; Horrocks L A
Separation of neutral lipids by high-performance liquid chromatography: quantification by ultraviolet, light scattering and fluorescence detection.
Journal of chromatography. B, Biomedical applications 1996;685(1):9-14.
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1996: Yang H C; Farooqui A A; Horrocks L A
Plasmalogen-selective phospholipase A2 and its role in signal transduction.
Journal of lipid mediators and cell signalling 1996;14(1-3):9-13.
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1996: Yang H C; Farooqui A A; Horrocks L A
Characterization of plasmalogen-selective phospholipase A2 from bovine brain.
Advances in experimental medicine and biology 1996;416():309-13.
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1995: Wells K; Farooqui A A; Liss L; Horrocks L A
Neural membrane phospholipids in Alzheimer disease.
Neurochemical research 1995;20(11):1329-33.
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1995: Farooqui A A; Yang H C; Horrocks L A
Plasmalogens, phospholipases A2 and signal transduction.
Brain research. Brain research reviews 1995;21(2):152-61.
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1995: Murphy E J; Haun S E; Rosenberger T A; Horrocks L A
Altered lipid metabolism in the presence and absence of extracellular Ca2+ during combined oxygen-glucose deprivation in primary astrocyte cultures.
Journal of neuroscience research 1995;42(1):109-16.
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1995: Segeleon J E; Lipscomb D C; Haun S E; Trapp V L; Horrocks L A
Astroglial phosphoinositide hydrolysis during combined glucose-oxygen deprivation: role of the metabotropic glutamate receptor.
Journal of neurochemistry 1995;65(3):1115-23.
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1995: Farooqui A A; Wells K; Horrocks L A
Breakdown of membrane phospholipids in Alzheimer disease. Involvement of excitatory amino acid receptors.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1995;25(2-3):155-73.
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1995: Haun S E; Trapp V L; Clotz M A; Horrocks L A
Nordihydroguaiaretic acid and RHC 80267 potentiate astroglial injury during combined glucose-oxygen deprivation.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1995;25(1):35-49.
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1994: Wells K; Anderson D K; Farooqui A A; Horrocks L A
Excitotoxicity of glutamate and four analogs in primary spinal cord cell cultures.
Neurochemistry international 1994;25(4):377-84.
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1994: Murphy E J; Behrmann D; Bates C M; Horrocks L A
Lipid alterations following impact spinal cord injury in the rat.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1994;23(1):13-26.
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1994: Farooqui A A; Yang H C; Horrocks L A
Purification of lipases, phospholipases and kinases by heparin-Sepharose chromatography.
Journal of chromatography. A 1994;673(2):149-58.
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1994: Farooqui A A; Horrocks L A
Involvement of glutamate receptors, lipases, and phospholipases in long-term potentiation and neurodegeneration.
Journal of neuroscience research 1994;38(1):6-11.
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1994: Yang H C; Farooqui A A; Horrocks L A
Effects of glycosaminoglycans and glycosphingolipids on cytosolic phospholipases A2 from bovine brain.
The Biochemical journal 1994;299 ( Pt 1)():91-5.
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1994: Yang H C; Farooqui A A; Horrocks L A
Effects of sialic acid and sialoglycoconjugates on cytosolic phospholipases A2 from bovine brain.
Biochemical and biophysical research communications 1994;199(3):1158-66.
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1994: Anderson D K; Dugan L L; Means E D; Horrocks L A
Methylprednisolone and membrane properties of primary cultures of mouse spinal cord.
Brain research 1994;637(1-2):119-25.
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1994: Farooqui A A; Horrocks L A
Excitotoxicity and neurological disorders: involvement of membrane phospholipids.
International review of neurobiology 1994;36():267-323.
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1993: Haun S E; Trapp V L; Horrocks L A
Hypothermia decreases astroglial injury and arachidonate release during combined glucose-oxygen deprivation.
Brain research 1993;631(2):352-6.
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1993: Murphy E J; Roberts E; Anderson D K; Horrocks L A
Cytotoxicity of aluminum silicates in primary neuronal cultures.
Neuroscience 1993;57(2):483-90.
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1993: Jurkowitz-Alexander M S; Altschuld R A; Haun S E; Stephens R E; Horrocks L A
Protection of ROC-1 hybrid glial cells by polyethylene glycol following ATP depletion.
Journal of neurochemistry 1993;61(4):1581-4.
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1993: Murphy E J; Roberts E; Horrocks L A
Aluminum silicate toxicity in cell cultures.
Neuroscience 1993;55(2):597-605.
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1993: Murphy E J; Stephens R; Jurkowitz-Alexander M; Horrocks L A
Acidic hydrolysis of plasmalogens followed by high-performance liquid chromatography.
Lipids 1993;28(6):565-8.
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1993: Murphy E J; Horrocks L A
Effects of differentiation on the phospholipid and phospholipid fatty acid composition of N1E-115 neuroblastoma cells.
Biochimica et biophysica acta 1993;1167(2):131-6.
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1993: Murphy E J; Anderson D K; Horrocks L A
Phospholipid and phospholipid fatty acid composition of mixed murine spinal cord neuronal cultures.
Journal of neuroscience research 1993;34(4):472-7.
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1993: Murphy E J; Slivka A P; Rosenberger T A; Horrocks L A
High-performance liquid chromatography separation and quantitation of methylprednisolone from rat brain.
Analytical biochemistry 1993;209(2):339-42.
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1993: Farooqui A A; Anderson D K; Horrocks L A
Effect of glutamate and its analogs on diacylglycerol and monoacylglycerol lipase activities of neuron-enriched cultures.
Brain research 1993;604(1-2):180-4.
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1993: Murphy E J; Horrocks L A
Composition of the phospholipids and their fatty acids in the ROC-1 oligodendroglial cell line.
Lipids 1993;28(1):67-71.
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1993: Murphy E J; Horrocks L A
A model for compression trauma: pressure-induced injury in cell cultures.
Journal of neurotrauma 1993;10(4):431-44.
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1992: Williams L L; Kiecolt-Glaser J K; Horrocks L A; Hillhouse J T; Glaser R
Quantitative association between altered plasma esterified omega-6 fatty acid proportions and psychological stress.
Prostaglandins, leukotrienes, and essential fatty acids 1992;47(2):165-70.
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1992: Haun S E; Murphy E J; Bates C M; Horrocks L A
Extracellular calcium is a mediator of astroglial injury during combined glucose-oxygen deprivation.
Brain research 1992;593(1):45-50.
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1992: Hirashima Y; Farooqui A A; Mills J S; Horrocks L A
Identification and purification of calcium-independent phospholipase A2 from bovine brain cytosol.
Journal of neurochemistry 1992;59(2):708-14.
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1992: Jurkowitz-Alexander M S; Altschuld R A; Hohl C M; Johnson J D; McDonald J S; Simmons T D; Horrocks L A
Cell swelling, blebbing, and death are dependent on ATP depletion and independent of calcium during chemical hypoxia in a glial cell line (ROC-1).
Journal of neurochemistry 1992;59(1):344-52.
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1992: Murphy E J; Joseph L; Stephens R; Horrocks L A
Phospholipid composition of cultured human endothelial cells.
Lipids 1992;27(2):150-3.
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1992: Farooqui A A; Hirashima Y; Horrocks L A
Brain phospholipases and their role in signal transduction.
Advances in experimental medicine and biology 1992;318():11-25.
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1991: Farooqui A A; Wallace L J; Horrocks L A
Stimulation of mono- and diacylglycerol lipase activities in ibotenate-induced lesions of nucleus basalis magnocellularis.
Neuroscience letters 1991;131(1):97-9.
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1991: Farooqui A A; Horrocks L A
Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disorders.
Brain research. Brain research reviews 1991;16(2):171-91.
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1990: Hirashima Y; Mills J S; Yates A J; Horrocks L A
Phospholipase A2 activities with a plasmalogen substrate in brain and in neural tumor cells: a sensitive and specific assay using pyrenesulfonyl-labeled plasmenylethanolamine.
Biochimica et biophysica acta 1990;1047(1):35-40.
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1990: Hirashima Y; Farooqui A A; Murphy E J; Horrocks L A
Purification of plasmalogens using Rhizopus delemar lipase and Naja naja naja phospholipase A2.
Lipids 1990;25(6):344-8.
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1990: Farooqui A A; Anderson D K; Flynn C; Bradel E; Means E D; Horrocks L A
Stimulation of mono- and diacylglycerol lipase activities by bradykinin in neural cultures.
Biochemical and biophysical research communications 1990;166(2):1001-9.
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1990: Farooqui A A; Liss L; Horrocks L A
Increased activities of lipolytic enzymes in Alzheimer's disease.
Advances in neurology 1990;51():127-9.
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1989: Hirashima Y; Farooqui A A; Horrocks L A
Fluorimetric coupled enzyme assay for lysoplasmalogenase activity in liver.
The Biochemical journal 1989;260(2):605-8.
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1989: Jurkowitz-Alexander M; Ebata H; Mills J S; Murphy E J; Horrocks L A
Solubilization, purification and characterization of lysoplasmalogen alkenylhydrolase (lysoplasmalogenase) from rat liver microsomes.
Biochimica et biophysica acta 1989;1002(2):203-12.
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1989: Farooqui A A; Rammohan K W; Horrocks L A
Isolation, characterization, and regulation of diacylglycerol lipases from the bovine brain.
Annals of the New York Academy of Sciences 1989;559():25-36.
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1989: Horrocks L A
Sources for brain arachidonic acid uptake and turnover in glycerophospholipids.
Annals of the New York Academy of Sciences 1989;559():17-24.
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1988: Williams L L; Doody D M; Horrocks L A
Serum fatty acid proportions are altered during the year following acute Epstein-Barr virus infection.
Lipids 1988;23(10):981-8.
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1988: Farooqui A A; Farooqui T; Yates A J; Horrocks L A
Regulation of protein kinase C activity by various lipids.
Neurochemical research 1988;13(6):499-511.
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1988: Farooqui A A; Liss L; Horrocks L A
Stimulation of lipolytic enzymes in Alzheimer's disease.
Annals of neurology 1988;23(3):306-8.
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1988: Farooqui A A; Liss L; Horrocks L A
Neurochemical aspects of Alzheimer's disease: involvement of membrane phospholipids.
Metabolic brain disease 1988;3(1):19-35.
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1987: Demediuk P; Saunders R D; Anderson D K; Means E D; Horrocks L A
Early membrane lipid changes in laminectomized and traumatized cat spinal cord.
Neurochemical pathology 1987;7(1):79-89.
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1987: Saunders R; Horrocks L A
Eicosanoids, plasma membranes, and molecular mechanisms of spinal cord injury.
Neurochemical pathology 1987;7(1):1-22.
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1987: Saunders R D; Dugan L L; Demediuk P; Means E D; Horrocks L A; Anderson D K
Effects of methylprednisolone and the combination of alpha-tocopherol and selenium on arachidonic acid metabolism and lipid peroxidation in traumatized spinal cord tissue.
Journal of neurochemistry 1987;49(1):24-31.
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1986: Dugan L L; Demediuk P; Pendley C E; Horrocks L A
Separation of phospholipids by high-performance liquid chromatography: all major classes, including ethanolamine and choline plasmalogens, and most minor classes, including lysophosphatidylethanolamine.
Journal of chromatography 1986;378(2):317-27.
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1986: Reddy T S; Horrocks L A
Effects of neonatal undernutrition of rats on the synthesis of phosphatidylcholine and phosphatidylethanolamine by microsomes from gray matter and white matter.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1986;4(1):89-95.
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1985: Demediuk P; Saunders R D; Anderson D K; Means E D; Horrocks L A
Membrane lipid changes in laminectomized and traumatized cat spinal cord.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(20):7071-5.
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1985: Demediuk P; Anderson D K; Horrocks L A; Means E D
Mechanical damage to murine neuronal-enriched cultures during harvesting: effects on free fatty acids, diglycerides, Na+,K+-ATPase, and lipid peroxidation.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1985;21(10):569-74.
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1985: Anderson D K; Demediuk P; Saunders R D; Dugan L L; Means E D; Horrocks L A
Spinal cord injury and protection.
Annals of emergency medicine 1985;14(8):816-21.
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1985: Horrocks L A; Demediuk P; Saunders R D; Dugan L; Clendenon N R; Means E D; Anderson D K
The degradation of phospholipids, formation of metabolites of arachidonic acid, and demyelination following experimental spinal cord injury.
Central nervous system trauma : journal of the American Paralysis Association 1985;2(2):115-20.
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1985: Anderson D K; Saunders R D; Demediuk P; Dugan L L; Braughler J M; Hall E D; Means E D; Horrocks L A
Lipid hydrolysis and peroxidation in injured spinal cord: partial protection with methylprednisolone or vitamin E and selenium.
Central nervous system trauma : journal of the American Paralysis Association 1985;2(4):257-67.
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1985: Demediuk P; Saunders R D; Clendenon N R; Means E D; Anderson D K; Horrocks L A
Changes in lipid metabolism in traumatized spinal cord.
Progress in brain research 1985;63():211-26.
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