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Rüdiger Horstkorte

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Yvonne Karbe; Juliane Pollscheit; Nicole Glaubitz; Rüdiger Horstkorte; Kaya Bork
Phosphorylation of Serine 774 of the Neural Cell Adhesion Molecule (NCAM) Is Involved in the Interaction with Collapsin Response Mediator Protein-2.
Mathias Aehle; Kaya Bork; Rüdiger Horstkorte; Artur Kuprijanov; Sebastian Schaepe; Rimvydas Simutis; Andreas Lübbert
Increasing batch-to-batch reproducibility of CHO-cell cultures using a model predictive control approach.
Anselm Werner; Dagobert Glanz; Rüdiger Horstkorte; Markus Berger; Karina Biskup; Véronique Blanchard; Kaya Bork
Glycoengineering the N-acyl side chain of sialic acid of human erythropoietin affects its resistance to sialidase.

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2013: Yvonne Karbe; Juliane Pollscheit; Nicole Glaubitz; Rüdiger Horstkorte; Kaya Bork
Phosphorylation of Serine 774 of the Neural Cell Adhesion Molecule (NCAM) Is Involved in the Interaction with Collapsin Response Mediator Protein-2.
Neurochemical research 2013;38(6):1229-35.
2012: Mathias Aehle; Kaya Bork; Rüdiger Horstkorte; Artur Kuprijanov; Sebastian Schaepe; Rimvydas Simutis; Andreas Lübbert
Increasing batch-to-batch reproducibility of CHO-cell cultures using a model predictive control approach.
Cytotechnology 2012;64(6):623-34.
2012: Anselm Werner; Dagobert Glanz; Rüdiger Horstkorte; Markus Berger; Karina Biskup; Véronique Blanchard; Kaya Bork
Glycoengineering the N-acyl side chain of sialic acid of human erythropoietin affects its resistance to sialidase.
Biological chemistry 2012;393(8):777-83.
2012: Manfred Wuhrer; Rüdiger Horstkorte
Highlight: dolce vita--a sample from European glycobiology.
Biological chemistry 2012;393(8):659.
2012: Anja Seifert; Dagobert Glanz; Nicole Glaubitz; Rüdiger Horstkorte; Kaya Bork
Polysialylation of the neural cell adhesion molecule: interfering with polysialylation and migration in neuroblastoma cells.
Archives of biochemistry and biophysics 2012;524(1):56-63.
2012: Juliane Pollscheit; Nicole Glaubitz; Hannes Haller; Rüdiger Horstkorte; Kaya Bork
Phosphorylation of serine 774 of the neural cell adhesion molecule is necessary for cyclic adenosine monophosphate response element binding protein activation and neurite outgrowth.
Journal of neuroscience research 2012;90(8):1577-82.
2012: Johannes Vogt; Birgit Weinhold; Anja U Brauer; Daniel Gagiannis; Robert Glumm; Bernd Heimrich; Herbert Hildebrandt; Martina Mühlenhoff; Thomas Naumann; Robert Nitsch; Werner Reutter; Benjamin Rister; Benjamin R Rost; Nic E Savaskan; Leslie Schlüter; Dietmar Schmitz; Nora Streu; B Suman Bharathi; Rüdiger Horstkorte
Homeostatic regulation of NCAM polysialylation is critical for correct synaptic targeting.
Cellular and molecular life sciences : CMLS 2012;69(7):1179-91.
2011: Wenke Weidemann; Anika Reinhardt; Annett Thate; Rüdiger Horstkorte
Biochemical characterization of the M712T-mutation of the UDP-N-acetylglucosamine 2-epimerase/N-acetyl-mannosaminekinase in hereditary inclusion body myopathy.
Neuromuscular disorders : NMD 2011;21(12):824-31.
2010: Kaya Bork; Yvonne Karbe; Juliane Pollscheit; Nicole Glaubitz; Sabine Nöhring; Rüdiger Horstkorte
Role of collapsin response mediator protein-2 in neurite outgrowth of PC12 cells.
Neuroreport 2010;21(9):641-5.
2010: Rüdiger Horstkorte; Stefan Reinke; Christian Bauer; Werner Reutter; Maria Kontou
N-Propionylmannosamine-induced over-expression and secretion of thioredoxin leads to neurite outgrowth of PC12 cells.
Biochemical and biophysical research communications 2010;395(3):296-300.
2010: Bettina Büttner; Rüdiger Horstkorte
Intracelluar ligands of NCAM.
Advances in experimental medicine and biology 2010;663():55-66.
2010: Wenke Weidemann; Christian Klukas; Andreas Klein; Andreas Simm; Falk Schreiber; Rüdiger Horstkorte
Lessons from GNE-deficient embryonic stem cells: sialic acid biosynthesis is involved in proliferation and gene expression.
Glycobiology 2010;20(1):107-17.
2009: Kaya Bork; Rüdiger Horstkorte; Wenke Weidemann
Increasing the sialylation of therapeutic glycoproteins: the potential of the sialic acid biosynthetic pathway.
Journal of pharmaceutical sciences 2009;98(10):3499-508.
2009: Maria Kontou; Wenke Weidemann; Kaya Bork; Rüdiger Horstkorte
Beyond glycosylation: sialic acid precursors act as signaling molecules and are involved in cellular control of differentiation of PC12 cells.
Biological chemistry 2009;390(7):575-9.
2008: Maria Kontou; Wenke Weidemann; Christian Bauer; Werner Reutter; Rüdiger Horstkorte
The key enzyme of sialic acid biosynthesis (GNE) promotes neurite outgrowth of PC12 cells.
Neuroreport 2008;19(12):1239-42.
2008: Maria Kontou; Christian Bauer; Werner Reutter; Rüdiger Horstkorte
Sialic acid metabolism is involved in the regulation of gene expression during neuronal differentiation of PC12 cells.
Glycoconjugate journal 2008;25(3):237-44.
2008: Kaya Bork; Christoph Kannicht; Sabine Nöhring; Werner Reutter; Wenke Weidemann; Gerald W Hart; Rüdiger Horstkorte
N-propanoylmannosamine interferes with O-GlcNAc modification of the tyrosine 3-monooxygenase and stimulates dopamine secretion.
Journal of neuroscience research 2008;86(3):647-52.
2007: Kaya Bork; Daniel Gagiannis; André Orthmann; Wenke Weidemann; Maria Kontou; Werner Reutter; Rüdiger Horstkorte
Experimental approaches to interfere with the polysialylation of the neural cell adhesion molecule in vitro and in vivo.
Journal of neurochemistry 2007;103 Suppl 1():65-71.
2007: Kaya Bork; Werner Reutter; Wenke Weidemann; Rüdiger Horstkorte
Enhanced sialylation of EPO by overexpression of UDP-GlcNAc 2-epimerase/ManAc kinase containing a sialuria mutation in CHO cells.
FEBS letters 2007;581(22):4195-8.
2007: Daniel Gagiannis; André Orthmann; Ilona Danssmann; Martina Schwarzkopf; Wenke Weidemann; Rüdiger Horstkorte
Reduced sialylation status in UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE)-deficient mice.
Glycoconjugate journal 2007;24(2-3):125-30.
2007: Daniel Gagiannis; Reinhart Gossrau; Werner Reutter; Martin Zimmermann-Kordmann; Rüdiger Horstkorte
Engineering the sialic acid in organs of mice using N-propanoylmannosamine.
Biochimica et biophysica acta 2007;1770(2):297-306.
2007: Ulf Gurok; Kaya Bork; Ulrike A Nuber; Ralf Spörle; Sabine Nöhring; Rüdiger Horstkorte
Expression of Ndufb11 encoding the neuronal protein 15.6 during neurite outgrowth and development.
Gene expression patterns : GEP 2007;7(3):370-4.
2006: Wenke Weidemann; Ulrich Stelzl; Ulrike Lisewski; Kaya Bork; Erich E Wanker; Stephan Hinderlich; Rüdiger Horstkorte
The collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), the key enzyme of sialic acid biosynthesis.
FEBS letters 2006;580(28-29):6649-54.
2006: Diana Mutz; Christoph Weise; Nadja Mechai; Werner Hofmann; Rüdiger Horstkorte; Gerold Brüning; Kerstin Danker
Integrin alpha3beta1 interacts with I1PP2A/lanp and phosphatase PP1.
Journal of neuroscience research 2006;84(8):1759-70.
2006: Stephanie Matthias; Rüdiger Horstkorte
Phosphorylation of the neural cell adhesion molecule on serine or threonine residues is induced by adhesion or nerve growth factor.
Journal of neuroscience research 2006;84(1):142-50.
2005: Nadja Mechai; Markus Wenzel; Manuel Koch; Lothar Lucka; Rüdiger Horstkorte; Werner Reutter; Kerstin Danker
The cytoplasmic tail of the alpha3 integrin subunit promotes neurite outgrowth in PC12 cells.
Journal of neuroscience research 2005;82(6):753-61.
2005: Kaya Bork; Werner Reutter; Rita Gerardy-Schahn; Rüdiger Horstkorte
The intracellular concentration of sialic acid regulates the polysialylation of the neural cell adhesion molecule.
FEBS letters 2005;579(22):5079-83.
2005: Bettina Büttner; Christoph Kannicht; Werner Reutter; Rüdiger Horstkorte
Novel cytosolic binding partners of the neural cell adhesion molecule: mapping the binding domains of PLC gamma, LANP, TOAD-64, syndapin, PP1, and PP2A.
Biochemistry 2005;44(18):6938-47.
2005: Sabine Krause; Stephan Hinderlich; Shira Amsili; Rüdiger Horstkorte; Heinz Wiendl; Zohar Argov; Stella Mitrani-Rosenbaum; Hanns Lochmüller
Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells.
Experimental cell research 2005;304(2):365-79.
2004: Astrid Blume; Wenke Weidemann; Ulrich Stelzl; Erich E Wanker; Lothar Lucka; Peter Donner; Werner Reutter; Rüdiger Horstkorte; Stephan Hinderlich
Domain-specific characteristics of the bifunctional key enzyme of sialic acid biosynthesis, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.
The Biochemical journal 2004;384(Pt 3):599-607.
2004: Gerard Farell; Erick Huang; Soo Y Kim; Rüdiger Horstkorte; John C Lieske
Modulation of proliferating renal epithelial cell affinity for calcium oxalate monohydrate crystals.
Journal of the American Society of Nephrology : JASN 2004;15(12):3052-62.
2004: Rüdiger Horstkorte; Martina Mühlenhoff; Werner Reutter; Sabine Nöhring; Martin Zimmermann-Kordmann; Rita Gerardy-Schahn
Selective inhibition of polysialyltransferase ST8SiaII by unnatural sialic acids.
Experimental cell research 2004;298(1):268-74.
2004: Rüdiger Horstkorte; Kirstin Rau; Stephan Laabs; Kerstin Danker; Werner Reutter
Biochemical engineering of the N-acyl side chain of sialic acid leads to increased calcium influx from intracellular compartments and promotes differentiation of HL60 cells.
FEBS letters 2004;571(1-3):99-102.
2004: Stephan Hinderlich; Ilan Salama; Iris Eisenberg; Tamara Potikha; Lars R Mantey; Kevin J Yarema; Rüdiger Horstkorte; Zohar Argov; Menachem Sadeh; Werner Reutter; Stella Mitrani-Rosenbaum
The homozygous M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase results in reduced enzyme activities but not in altered overall cellular sialylation in hereditary inclusion body myopathy.
FEBS letters 2004;566(1-3):105-9.
2004: Rüdiger Horstkorte; Kirstin Rau; Werner Reutter; Sabine Nöhring; Lothar Lucka
Increased expression of the selectin ligand sialyl-Lewis(x) by biochemical engineering of sialic acids.
Experimental cell research 2004;295(2):549-54.
2004: Bettina Büttner; Werner Reutter; Rüdiger Horstkorte
Cytoplasmic domain of NCAM 180 reduces NCAM-mediated neurite outgrowth.
Journal of neuroscience research 2004;75(6):854-60.
2003: Bettina Büttner; Christoph Kannicht; Werner Reutter; Rüdiger Horstkorte
The neural cell adhesion molecule is associated with major components of the cytoskeleton.
Biochemical and biophysical research communications 2003;310(3):967-71.
2002: Bettina Büttner; Christoph Kannicht; Carolin Schmidt; Klemens Löster; Werner Reutter; Hye-Youn Lee; Sabine Nöhring; Rüdiger Horstkorte
Biochemical engineering of cell surface sialic acids stimulates axonal growth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(20):8869-75.
2002: Pablo Villavicencio-Lorini; Stephan Laabs; Kerstin Danker; Werner Reutter; Rüdiger Horstkorte
Biochemical engineering of the acyl side chain of sialic acids stimulates integrin-dependent adhesion of HL60 cells to fibronectin.
Journal of molecular medicine (Berlin, Germany) 2002;80(10):671-7.
2002: Martina Schwarzkopf; Klaus-Peter Knobeloch; Elvira Rohde; Stephan Hinderlich; Nicola Wiechens; Lothar Lucka; Ivan Horak; Werner Reutter; Rüdiger Horstkorte
Sialylation is essential for early development in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5267-70.
2001: Kerstin Danker; Nadja Mechai; Lothar Lucka; Werner Reutter; Rüdiger Horstkorte
The small Gtpase ras is involved in growth factor-regulated expression of the alpha1 integrin subunit in PC12 cells.
Biological chemistry 2001;382(6):969-72.
2001: Rüdiger Horstkorte; H Y Lee; Lothar Lucka; Kerstin Danker; Lars R Mantey; Werner Reutter
Biochemical engineering of the side chain of sialic acids increases the biological stability of the highly sialylated cell adhesion molecule CEACAM1.
Biochemical and biophysical research communications 2001;283(1):31-5.
2000: Dörte Vossmeyer; C Kaufmann; Klemens Löster; Lothar Lucka; Rüdiger Horstkorte; Werner Reutter; Kerstin Danker
The cytoplasmic domain of the alpha1 integrin subunit influences stress fiber formation via the conserved GFFKR motif.
Experimental cell research 2000;256(1):321-7.
2000: Rüdiger Horstkorte; Sabine Nöhring; Kerstin Danker; K Effertz; Werner Reutter; Lothar Lucka
Protein kinase C phosphorylates and regulates UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase.
FEBS letters 2000;470(3):315-8.
2000: Klemens Löster; Rüdiger Horstkorte
Enzymatic quantification of cell-matrix and cell-cell adhesion.
Micron (Oxford, England : 1993) 2000;31(1):41-53.
1999: Lothar Lucka; M Krause; Kerstin Danker; Werner Reutter; Rüdiger Horstkorte
Primary structure and expression analysis of human UDP-N-acetyl-glucosamine-2-epimerase/N-acetylmannosamine kinase, the bifunctional enzyme in neuraminic acid biosynthesis.
FEBS letters 1999;454(3):341-4.
1999: Lothar Lucka; Matthias Budt; I Cichocka; Kerstin Danker; Rüdiger Horstkorte; Werner Reutter
C-CAM-mediated adhesion leads to an outside-in dephosphorylation signal.
European journal of biochemistry / FEBS 1999;262(2):541-6.
1999: Rüdiger Horstkorte; Sabine Nöhring; N Wiechens; Martina Schwarzkopf; Kerstin Danker; Werner Reutter; Lothar Lucka
Tissue expression and amino acid sequence of murine UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase.
European journal of biochemistry / FEBS 1999;260(3):923-7.
1999: Rüdiger Horstkorte; N Lessner; Rita Gerardy-Schahn; Lothar Lucka; Kerstin Danker; Werner Reutter
Expression of the polysialyltransferase ST8SiaIV: polysialylation interferes with adhesion of PC12 cells in vitro.
Experimental cell research 1999;246(1):122-8.
1998: Lothar Lucka; S Sel; Kerstin Danker; Rüdiger Horstkorte; Werner Reutter
Carcinoembryonic antigen-related cell-cell adhesion molecule C-CAM is greatly increased in serum and urine of rats with liver diseases.
FEBS letters 1998;438(1-2):37-40.
1997: T U Park; Lothar Lucka; Werner Reutter; Rüdiger Horstkorte
Turnover studies of the neural cell adhesion molecule NCAM: degradation of NCAM in PC12 cells depends on the presence of NGF.
Biochemical and biophysical research communications 1997;234(3):686-9.
1997: Klemens Löster; C Schüler; C Heidrich; Rüdiger Horstkorte; Werner Reutter
Quantification of cell-matrix and cell-cell adhesion using horseradish peroxidase.
Analytical biochemistry 1997;244(1):96-102.
1996: Rüdiger Horstkorte; H Fan; Werner Reutter
Rapid isolation of endosomes from BHK cells: identification of DPP IV (CD26) in endosomes.
Experimental cell research 1996;226(2):398-401.