Rüdiger Horstkorte

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Bork Kaya; Horstkorte Rüdiger; Weidemann Wenke
Increasing the sialylation of therapeutic glycoproteins: the potential of the sialic acid biosynthetic pathway.
Kontou Maria; Weidemann Wenke; Bork Kaya; Horstkorte Rüdiger
Beyond glycosylation: sialic acid precursors act as signaling molecules and are involved in cellular control of differentiation of PC12 cells.
Kontou Maria; Weidemann Wenke; Bauer Christian; Reutter Werner; Horstkorte Rüdiger
The key enzyme of sialic acid biosynthesis (GNE) promotes neurite outgrowth of PC12 cells.

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2009: Bork Kaya; Horstkorte Rüdiger; Weidemann Wenke
Increasing the sialylation of therapeutic glycoproteins: the potential of the sialic acid biosynthetic pathway.
Journal of pharmaceutical sciences 2009;98(10):3499-508.
2009: Kontou Maria; Weidemann Wenke; Bork Kaya; Horstkorte Rüdiger
Beyond glycosylation: sialic acid precursors act as signaling molecules and are involved in cellular control of differentiation of PC12 cells.
Biological chemistry 2009;390(7):575-9.
2008: Kontou Maria; Weidemann Wenke; Bauer Christian; Reutter Werner; Horstkorte Rüdiger
The key enzyme of sialic acid biosynthesis (GNE) promotes neurite outgrowth of PC12 cells.
Neuroreport 2008;19(12):1239-42.
2008: Kontou Maria; Bauer Christian; Reutter Werner; Horstkorte Rüdiger
Sialic acid metabolism is involved in the regulation of gene expression during neuronal differentiation of PC12 cells.
Glycoconjugate journal 2008;25(3):237-44.
2008: Bork Kaya; Kannicht Christoph; Nöhring Sabine; Reutter Werner; Weidemann Wenke; Hart Gerald W; Horstkorte Rüdiger
N-propanoylmannosamine interferes with O-GlcNAc modification of the tyrosine 3-monooxygenase and stimulates dopamine secretion.
Journal of neuroscience research 2008;86(3):647-52.
2007: Bork Kaya; Gagiannis Daniel; Orthmann André; Weidemann Wenke; Kontou Maria; Reutter Werner; Horstkorte Rüdiger
Experimental approaches to interfere with the polysialylation of the neural cell adhesion molecule in vitro and in vivo.
Journal of neurochemistry 2007;103 Suppl 1():65-71.
2007: Bork Kaya; Reutter Werner; Weidemann Wenke; Horstkorte Rüdiger
Enhanced sialylation of EPO by overexpression of UDP-GlcNAc 2-epimerase/ManAc kinase containing a sialuria mutation in CHO cells.
FEBS letters 2007;581(22):4195-8.
2007: Gagiannis Daniel; Orthmann André; Danssmann Ilona; Schwarzkopf Martina; Weidemann Wenke; Horstkorte Rüdiger
Reduced sialylation status in UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE)-deficient mice.
Glycoconjugate journal 2007;24(2-3):125-30.
2007: Gagiannis Daniel; Gossrau Reinhart; Reutter Werner; Zimmermann-Kordmann Martin; Horstkorte Rüdiger
Engineering the sialic acid in organs of mice using N-propanoylmannosamine.
Biochimica et biophysica acta 2007;1770(2):297-306.
2007: Gurok Ulf; Bork Kaya; Nuber Ulrike; Spörle Ralf; Nöhring Sabine; Horstkorte Rüdiger
Expression of Ndufb11 encoding the neuronal protein 15.6 during neurite outgrowth and development.
Gene expression patterns : GEP 2007;7(3):370-4.
2006: Weidemann Wenke; Stelzl Ulrich; Lisewski Ulrike; Bork Kaya; Wanker Erich E; Hinderlich Stephan; Horstkorte Rüdiger
The collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), the key enzyme of sialic acid biosynthesis.
FEBS letters 2006;580(28-29):6649-54.
2006: Mutz Diana; Weise Christoph; Mechai Nadja; Hofmann Werner; Horstkorte Rüdiger; Brüning Gerold; Danker Kerstin
Integrin alpha3beta1 interacts with I1PP2A/lanp and phosphatase PP1.
Journal of neuroscience research 2006;84(8):1759-70.
2006: Matthias Stephanie; Horstkorte Rüdiger
Phosphorylation of the neural cell adhesion molecule on serine or threonine residues is induced by adhesion or nerve growth factor.
Journal of neuroscience research 2006;84(1):142-50.
2005: Mechai Nadja; Wenzel Markus; Koch Manuel; Lucka Lothar; Horstkorte Rüdiger; Reutter Werner; Danker Kerstin
The cytoplasmic tail of the alpha3 integrin subunit promotes neurite outgrowth in PC12 cells.
Journal of neuroscience research 2005;82(6):753-61.
2005: Bork Kaya; Reutter Werner; Gerardy-Schahn Rita; Horstkorte Rüdiger
The intracellular concentration of sialic acid regulates the polysialylation of the neural cell adhesion molecule.
FEBS letters 2005;579(22):5079-83.
2005: Büttner Bettina; Kannicht Christoph; Reutter Werner; Horstkorte Rüdiger
Novel cytosolic binding partners of the neural cell adhesion molecule: mapping the binding domains of PLC gamma, LANP, TOAD-64, syndapin, PP1, and PP2A.
Biochemistry 2005;44(18):6938-47.
2005: Krause Sabine; Hinderlich Stephan; Amsili Shira; Horstkorte Rüdiger; Wiendl Heinz; Argov Zohar; Mitrani-Rosenbaum Stella; Lochmüller Hanns
Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells.
Experimental cell research 2005;304(2):365-79.
2004: Farell Gerard; Huang Erick; Kim Soo Y; Horstkorte Rüdiger; Lieske John C
Modulation of proliferating renal epithelial cell affinity for calcium oxalate monohydrate crystals.
Journal of the American Society of Nephrology : JASN 2004;15(12):3052-62.
2004: Blume Astrid; Weidemann Wenke; Stelzl Ulrich; Wanker Erich E; Lucka Lothar; Donner Peter; Reutter Werner; Horstkorte Rüdiger; Hinderlich Stephan
Domain-specific characteristics of the bifunctional key enzyme of sialic acid biosynthesis, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.
The Biochemical journal 2004;384(Pt 3):599-607.
2004: Horstkorte Rüdiger; Mühlenhoff Martina; Reutter Werner; Nöhring Sabine; Zimmermann-Kordmann Martin; Gerardy-Schahn Rita
Selective inhibition of polysialyltransferase ST8SiaII by unnatural sialic acids.
Experimental cell research 2004;298(1):268-74.
2004: Horstkorte Rüdiger; Rau Kirstin; Laabs Stephan; Danker Kerstin; Reutter Werner
Biochemical engineering of the N-acyl side chain of sialic acid leads to increased calcium influx from intracellular compartments and promotes differentiation of HL60 cells.
FEBS letters 2004;571(1-3):99-102.
2004: Hinderlich Stephan; Salama Ilan; Eisenberg Iris; Potikha Tamara; Mantey Lars R; Yarema Kevin J; Horstkorte Rüdiger; Argov Zohar; Sadeh Menachem; Reutter Werner; Mitrani-Rosenbaum Stella
The homozygous M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase results in reduced enzyme activities but not in altered overall cellular sialylation in hereditary inclusion body myopathy.
FEBS letters 2004;566(1-3):105-9.
2004: Horstkorte Rüdiger; Rau Kirstin; Reutter Werner; Nöhring Sabine; Lucka Lothar
Increased expression of the selectin ligand sialyl-Lewis(x) by biochemical engineering of sialic acids.
Experimental cell research 2004;295(2):549-54.
2004: Büttner Bettina; Reutter Werner; Horstkorte Rüdiger
Cytoplasmic domain of NCAM 180 reduces NCAM-mediated neurite outgrowth.
Journal of neuroscience research 2004;75(6):854-60.
2003: Büttner Bettina; Kannicht Christoph; Reutter Werner; Horstkorte Rüdiger
The neural cell adhesion molecule is associated with major components of the cytoskeleton.
Biochemical and biophysical research communications 2003;310(3):967-71.
2002: Villavicencio-Lorini Pablo; Laabs Stephan; Danker Kerstin; Reutter Werner; Horstkorte Rüdiger
Biochemical engineering of the acyl side chain of sialic acids stimulates integrin-dependent adhesion of HL60 cells to fibronectin.
Journal of molecular medicine (Berlin, Germany) 2002;80(10):671-7.
2002: Büttner Bettina; Kannicht Christoph; Schmidt Carolin; Löster Klemens; Reutter Werner; Lee Hye-Youn; Nöhring Sabine; Horstkorte Rüdiger
Biochemical engineering of cell surface sialic acids stimulates axonal growth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(20):8869-75.
2002: Schwarzkopf Martina; Knobeloch Klaus-Peter; Rohde Elvira; Hinderlich Stephan; Wiechens Nicola; Lucka Lothar; Horak Ivan; Reutter Werner; Horstkorte Rüdiger
Sialylation is essential for early development in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5267-70.
2001: Danker K; Mechai N; Lucka L; Reutter W; Horstkorte R
The small Gtpase ras is involved in growth factor-regulated expression of the alpha1 integrin subunit in PC12 cells.
Biological chemistry 2001;382(6):969-72.
2001: Horstkorte R; Lee H Y; Lucka L; Danker K; Mantey L; Reutter W
Biochemical engineering of the side chain of sialic acids increases the biological stability of the highly sialylated cell adhesion molecule CEACAM1.
Biochemical and biophysical research communications 2001;283(1):31-5.
2000: Vossmeyer D; Kaufmann C; Löster K; Lucka L; Horstkorte R; Reutter W; Danker K
The cytoplasmic domain of the alpha1 integrin subunit influences stress fiber formation via the conserved GFFKR motif.
Experimental cell research 2000;256(1):321-7.
2000: Horstkorte R; Nöhring S; Danker K; Effertz K; Reutter W; Lucka L
Protein kinase C phosphorylates and regulates UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase.
FEBS letters 2000;470(3):315-8.
2000: Löster K; Horstkorte R
Enzymatic quantification of cell-matrix and cell-cell adhesion.
Micron (Oxford, England : 1993) 2000;31(1):41-53.
1999: Lucka L; Krause M; Danker K; Reutter W; Horstkorte R
Primary structure and expression analysis of human UDP-N-acetyl-glucosamine-2-epimerase/N-acetylmannosamine kinase, the bifunctional enzyme in neuraminic acid biosynthesis.
FEBS letters 1999;454(3):341-4.
1999: Lucka L; Budt M; Cichocka I; Danker K; Horstkorte R; Reutter W
C-CAM-mediated adhesion leads to an outside-in dephosphorylation signal.
European journal of biochemistry / FEBS 1999;262(2):541-6.
1999: Horstkorte R; Nöhring S; Wiechens N; Schwarzkopf M; Danker K; Reutter W; Lucka L
Tissue expression and amino acid sequence of murine UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase.
European journal of biochemistry / FEBS 1999;260(3):923-7.
1999: Horstkorte R; Lessner N; Gerardy-Schahn R; Lucka L; Danker K; Reutter W
Expression of the polysialyltransferase ST8SiaIV: polysialylation interferes with adhesion of PC12 cells in vitro.
Experimental cell research 1999;246(1):122-8.
1998: Lucka L; Sel S; Danker K; Horstkorte R; Reutter W
Carcinoembryonic antigen-related cell-cell adhesion molecule C-CAM is greatly increased in serum and urine of rats with liver diseases.
FEBS letters 1998;438(1-2):37-40.
1997: Park T U; Lucka L; Reutter W; Horstkorte R
Turnover studies of the neural cell adhesion molecule NCAM: degradation of NCAM in PC12 cells depends on the presence of NGF.
Biochemical and biophysical research communications 1997;234(3):686-9.
1997: Löster K; Schüler C; Heidrich C; Horstkorte R; Reutter W
Quantification of cell-matrix and cell-cell adhesion using horseradish peroxidase.
Analytical biochemistry 1997;244(1):96-102.
1996: Horstkorte R; Fan H; Reutter W
Rapid isolation of endosomes from BHK cells: identification of DPP IV (CD26) in endosomes.
Experimental cell research 1996;226(2):398-401.

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Rüdiger Horstkorte

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