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Steve Horvath

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TOP 3
Peter Langfelder; Paul S Mischel; Steve Horvath
When is hub gene selection better than standard meta-analysis?
Andrew J Levine; Jeremy A Miller; Susan Morgello; Paul Shapshak; Elyse J Singer; Deborah Commins; Benjamin Gelman; Igor Grant; Charles H Hinkin; Steve Horvath
Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer's disease.
Lin Song; Peter Langfelder; Steve Horvath
Random generalized linear model: a highly accurate and interpretable ensemble predictor.

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All Publications

2013: Peter Langfelder; Paul S Mischel; Steve Horvath
When is hub gene selection better than standard meta-analysis?
PloS one 2013;8(4):e61505.
2013: Andrew J Levine; Jeremy A Miller; Susan Morgello; Paul Shapshak; Elyse J Singer; Deborah Commins; Benjamin Gelman; Igor Grant; Charles H Hinkin; Steve Horvath
Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer's disease.
BMC medical genomics 2013;6():4.
2013: Lin Song; Peter Langfelder; Steve Horvath
Random generalized linear model: a highly accurate and interpretable ensemble predictor.
BMC bioinformatics 2013;14():5.
2012: James N Weiss; Nicholas Wisniewski; Mario Deng; Eleazar Eskin; Steve Horvath; Alain Karma; W Robb MacLellan; Zhilin Qu; Christoph D Rau; Colin M Rees; Jessica Wang; Yibin Wang; Aldons J Lusis
"Good enough solutions" and the genetics of complex diseases.
Circulation research 2012;111(4):493-504.
2012: Dyna I Shirasaki; Ismael Al-Ramahi; Pinmanee Boontheung; Juan Botas; Giovanni Coppola; Daniel H Geschwind; Michelle Gray; Erin R Greiner; Steve Horvath; Joseph A Loo; X William Yang
Network organization of the huntingtin proteomic interactome in mammalian brain.
Neuron 2012;75(1):41-57.
2012: Peter Langfelder; Aldons J Lusis; Lawrence W Castellani; Richard Davis; Steve Horvath; Eric Paul; Eric E Schadt; Zhiqiang Zhou; Margarete Mehrabian
A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models.
Biochimica et biophysica acta 2012;1821(3):435-47.
2012: Austin T Hilliard; Steve Horvath; Julie E Miller; Elizabeth R Fraley; Stephanie A White
Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning.
Neuron 2012;73(3):537-52.
2012: Blake E Haas; Steve Horvath; Jaakko Kaprio; Johanna Kuusisto; Markku Laakso; Elina Nikkola; Carlos A Aguilar-Salinas; Rita M Cantor; Mete Civelek; Ivette Cruz-Bautista; Kirsi H Pietiläinen; Laura Riba; Aila Rissanen; Teresa Tusie-Luna; Daphna Weissglas-Volkov; Päivi Pajukanta
Adipose co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes.
BMC medical genomics 2012;5():61.
2012: Lin Song; Peter Langfelder; Steve Horvath
Comparison of co-expression measures: mutual information, correlation, and model based indices.
BMC bioinformatics 2012;13():328.
2012: Austin T Hilliard; Steve Horvath; Julie E Miller; Stephanie A White
Distinct neurogenomic states in basal ganglia subregions relate differently to singing behavior in songbirds.
PLoS computational biology 2012;8(11):e1002773.
2012: Andrew F Leuchter; Aimee M Hunter; Chaochao Cai; Ian A Cook; Steve Horvath
Resting-state quantitative electroencephalography reveals increased neurophysiologic connectivity in depression.
PloS one 2012;7(2):e32508.
2011: Anyou Wang; Zhigang Xue; Chaochao Cai; Steve Horvath; Kevin Huang; Yin Shen; Guoping Fan
Functional modules distinguish human induced pluripotent stem cells from embryonic stem cells.
Stem cells and development 2011;20(11):1937-50.
2011: Vei Mah; Erin L Maresh; Diana Marquez; Richard Pietras; Nam Yoon; Li Zhang; Mohammad Alavi; Lora Bagryanova; David Chia; Michael C Fishbein; Steve Horvath; Lee Goodglick
Expression levels of estrogen receptor beta in conjunction with aromatase predict survival in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2011;74(2):318-25.
2011: Diana C Marquez-Garban; Mohammad Alavi; Lora Bagryanova; Hsiao-Wang Chen; David Chia; Edward Garon; Lee Goodglick; Steve Horvath; Vei Mah; Erin L Maresh; Richard J Pietras
Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer.
Steroids 2011;76(9):910-20.
2011: Irina Voineagu; Xinchen Wang; Benjamin J Blencowe; Rita M Cantor; Steve Horvath; Patrick Johnston; Jennifer K Lowe; Jonathan Mill; Yuan Tian; Daniel Geschwind
Transcriptomic analysis of autistic brain reveals convergent molecular pathology.
Nature 2011;474(7351):380-4.
2011: Jeremy A Miller; Daniel R Salomon; Chaochao Cai; Daniel Geschwind; Sunil M Kurian; Peter Langfelder; Steve Horvath
Strategies for aggregating gene expression data: the collapseRows R function.
BMC bioinformatics 2011;12():322.
2011: Sven Bocklandt; Steve Horvath; Wen Lin; Francisco Sánchez; Mary Sehl; Janet S Sinsheimer; Eric Vilain
Epigenetic predictor of age.
PloS one 2011;6(6):e14821.
2011: Sara Huerta-Yepez; Vei Mah; Erin L Maresh; Clara M Rivera-Pazos; Mario I Vega; Nam K Yoon; Benjamin Bonavida; Devasis Chatterjee; David Chia; Angeles Hernandez-Cueto; Steve Horvath; Lee Goodglick
Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival.
BMC cancer 2011;11():259.
2011: Angela P Presson; Ayyappan K Rajasekaran; Nam K Yoon; Vei Mah; Erin L Maresh; Mohammad Alavi; Lora Bagryanova; David Chia; Lee Goodglick; Steve Horvath
Protein expression based multimarker analysis of breast cancer samples.
BMC cancer 2011;11():230.
2011: Christopher C Park; Greg D Gale; Simone de Jong; Anatole Ghazalpour; Brian J Bennett; Charles Farber; Peter Langfelder; Andy Lin; Arshad H Khan; Eleazar Eskin; Steve Horvath; Aldons J Lusis; Roel A Ophoff; Desmond J Smith
Gene networks associated with conditional fear in mice identified using a systems genetics approach.
BMC systems biology 2011;5():43.
2011: Peter Langfelder; Rui Luo; Michael C Oldham; Steve Horvath
Is my network module preserved and reproducible?
PLoS computational biology 2011;7(1):e1001057.
2010: Nam K Yoon; Erin L Maresh; Dejun Shen; Yahya Elshimali; Sophia Apple; Steve Horvath; Vei Mah; Shikha Bose; David Chia; Helena R Chang; Lee Goodglick
Higher levels of GATA3 predict better survival in women with breast cancer.
Human pathology 2010;41(12):1794-801.
2010: Omar Habeeb; Lee Goodglick; Robert A Soslow; Rajiv G Rao; Lynn K Gordon; Osvaldo Schirripa; Steve Horvath; Jonathan Braun; David B Seligson; Madhuri Wadehra
Epithelial membrane protein-2 expression is an early predictor of endometrial cancer development.
Cancer 2010;116(20):4718-26.
2010: Aik T Ooi; Vei Mah; Derek W Nickerson; Jennifer L Gilbert; Vi Luan Ha; Ahmed E Hegab; Steve Horvath; Mohammad Alavi; Erin L Maresh; David Chia; Adam C Gower; Marc E Lenburg; Avrum Spira; Luisa M Solis; Ignacio I Wistuba; Tonya C Walser; William D Wallace; Steven M Dubinett; Lee Goodglick; Brigitte N Gomperts
Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.
Cancer research 2010;70(16):6639-48.
2010: Jeremy A Miller; Steve Horvath; Daniel Geschwind
Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(28):12698-703.
2010: Brandon H Le; Chen Cheng; Anhthu Q Bui; Javier A Wagmaister; Kelli F Henry; Julie Pelletier; Linda Kwong; Mark Belmonte; Ryan Kirkbride; Steve Horvath; Gary N Drews; Robert L Fischer; Jack K Okamuro; John J Harada; Robert B Goldberg
Global analysis of gene activity during Arabidopsis seed development and identification of seed-specific transcription factors.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(18):8063-70.
2010: Ananya Manuyakorn; Rebecca Paulus; James Farrell; Nicole A Dawson; Sheila Tze; Gardenia Cheung-Lau; Oscar Joe Hines; Howard Reber; David B Seligson; Steve Horvath; Siavash K Kurdistani; Chandan Guha; David W Dawson
Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(8):1358-65.
2010: Erin L Maresh; Vei Mah; Mohammad Alavi; Steve Horvath; Lora Bagryanova; Emily S Liebeskind; Laura A Knutzen; Yong Zhou; David Chia; Alvin Y Liu; Lee Goodglick
Differential expression of anterior gradient gene AGR2 in prostate cancer.
BMC cancer 2010;10():680.
2010: Chaochao Cai; Peter Langfelder; Tova F Fuller; Michael C Oldham; Rui Luo; Leonard H van den Berg; Roel A Ophoff; Steve Horvath
Is human blood a good surrogate for brain tissue in transcriptional studies?
BMC genomics 2010;11():589.
2010: Nam K Yoon; Erin L Maresh; Yahya Elshimali; Ai Li; Steve Horvath; David Seligson; David Chia; Lee Goodglick
Elevated MED28 expression predicts poor outcome in women with breast cancer.
BMC cancer 2010;10():335.
2009: Christopher Plaisier; Steve Horvath; Adriana Huertas-Vazquez; Ivette Cruz-Bautista; Miguel F Herrera; Teresa Tusie-Luna; Carlos Aguilar Salinas; Päivi Pajukanta
A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia.
PLoS genetics 2009;5(9):e1000642.
2009: Nicole K MacLennan; Jun Dong; Jason E Aten; Steve Horvath; Lola Rahib; Loren Ornelas; Katrina M Dipple; Edward R B McCabe
Weighted gene co-expression network analysis identifies biomarkers in glycerol kinase deficient mice.
Molecular genetics and metabolism 2009;98(1-2):203-14.
2009: Charles Farber; Jason E Aten; Emily A Farber; Vincent de Vera; Rodrigo Gularte; Alma Islas-Trejo; Pengzi Wen; Steve Horvath; Michael Lucero; Aldons J Lusis; Juan F Medrano
Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling.
Physiological genomics 2009;37(3):294-302.
2009: David B Seligson; Steve Horvath; Matthew A McBrian; Vei Mah; Hong Yu; Sheila Tze; Qun Wang; David Chia; Lee Goodglick; Siavash K Kurdistani
Global levels of histone modifications predict prognosis in different cancers.
The American journal of pathology 2009;174(5):1619-28.
2009: Dan R Laks; Michael Masterman-Smith; Koppany Visnyei; brigitte Angénieux; Nicholas M Orozco; Ian Foran; William H Yong; Harry V Vinters; Linda M Liau; Jorge A Lazareff; Paul S Mischel; Timothy F Cloughesy; Steve Horvath; Harley I Kornblum
Neurosphere formation is an independent predictor of clinical outcome in malignant glioma.
Stem cells (Dayton, Ohio) 2009;27(4):980-7.
2009: Atila Van Nas; Debraj Guhathakurta; Susanna S Wang; Nadir Yehya; Steve Horvath; Bin Zhang; Leslie Ingram-Drake; Gautam Chaudhuri; Eric E Schadt; Thomas A Drake; Arthur P Arnold; Aldons J Lusis
Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks.
Endocrinology 2009;150(3):1235-49.
2009: Rupa Sridharan; Jason Tchieu; Mike J Mason; Robin Yachechko; Edward Kuoy; Steve Horvath; Qing Zhou; Kathrin Plath
Role of the murine reprogramming factors in the induction of pluripotency.
Cell 2009;136(2):364-77.
2009: Deliang Guo; Robert M Prins; Julie Dang; Daisuke Kuga; Akio Iwanami; Horacio Soto; Kelly Y Lin; Tiffany T Huang; David Akhavan; M Benjamin Hock; Shaojun Zhu; Ava A Kofman; Steve J Bensinger; William H Yong; Harry V Vinters; Steve Horvath; Andrew D Watson; John Kuhn; H Ian Robins; Minesh Mehta; Patrick Y Wen; Lisa De Angelis; Michael D Prados; Ingo K Mellinghoff; Timothy F Cloughesy; Paul S Mischel
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy.
Science signaling 2009;2(101):ra82.
2009: Nam K Yoon; David B Seligson; David Chia; Yahya Elshimali; Giri Sulur; Ai Li; Steve Horvath; Erin Maresh; Vei Mah; Shikha Bose; Benjamin Bonavida; Lee Goodglick
Higher expression levels of 14-3-3sigma in ductal carcinoma in situ of the breast predict poorer outcome.
Cancer biomarkers : section A of Disease markers 2009;5(4):215-24.
2009: Kellen D Winden; Michael C Oldham; Karoly Mirnics; Philip J Ebert; Christo H Swan; Pat Levitt; John L Rubenstein; Steve Horvath; Daniel Geschwind
The organization of the transcriptional network in specific neuronal classes.
Molecular systems biology 2009;5():291.
2009: Ai Li; Steve Horvath
Network module detection: Affinity search technique with the multi-node topological overlap measure.
BMC research notes 2009;2():142.
2009: Mike J Mason; Guoping Fan; Kathrin Plath; Qing Zhou; Steve Horvath
Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells.
BMC genomics 2009;10():327.
2009: Shen Hu; Michael Zhou; Jiang Jiang; Jianghua Wang; David Elashoff; Sven Gorr; Sara A Michie; Fred K L Spijkervet; Hendrika Bootsma; Cees G M Kallenberg; Arjan Vissink; Steve Horvath; David T Wong
Systems biology analysis of Sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands.
Arthritis and rheumatism 2009;60(1):81-92.
2008: Michael C Oldham; Genevieve Konopka; Kazuya Iwamoto; Peter Langfelder; Tadafumi Kato; Steve Horvath; Daniel Geschwind
Functional organization of the transcriptome in human brain.
Nature neuroscience 2008;11(11):1271-82.
2008: Yanqing Chen; Jun Zhu; Pek Yee Lum; Xia Yang; Shirly Pinto; Douglas J MacNeil; Chunsheng Zhang; john lamb; Stephen Wilton Edwards; Solveig K Sieberts; Amy Leonardson; Lawrence W Castellini; Susanna Wang; Marie-France Champy; Bin Zhang; Valur Emilsson; Sudheer Doss; Anatole Ghazalpour; Steve Horvath; Thomas A Drake; Aldons J Lusis; Eric E Schadt
Variations in DNA elucidate molecular networks that cause disease.
Nature 2008;452(7186):429-35.
2008: Peter Langfelder; Bin Zhang; Steve Horvath
Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R.
Bioinformatics (Oxford, England) 2008;24(5):719-20.
2008: Timothy F Cloughesy; Koji Yoshimoto; Phioanh Nghiemphu; Kevin Brown; Julie Dang; Shaojun Zhu; Teli Hsueh; Yinan Chen; Wei Wang; David Youngkin; Linda M Liau; Neil Martin; Don Becker; Marvin Bergsneider; Albert Lai; Richard Green; Tom Oglesby; Michael Koleto; Jeffrey M. Trent; Steve Horvath; Paul S Mischel; Ingo K Mellinghoff; Charles L Sawyers
Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma.
PLoS medicine 2008;5(1):e8.
2008: Koji Yoshimoto; Julie Dang; Shaojun Zhu; David Nathanson; Tiffany Huang; Rebecca Dumont; David Seligson; William H Yong; Zhenggang Xiong; Nagesh Rao; Henrik Winther; Arnab Chakravarti; Darell D Bigner; Ingo K Mellinghoff; Steve Horvath; Webster K Cavenee; Timothy F Cloughesy; Paul S Mischel
Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(2):488-93.
2008: Peter Langfelder; Steve Horvath
WGCNA: an R package for weighted correlation network analysis.
BMC bioinformatics 2008;9():559.
2008: Angela P Presson; Eric M Sobel; Jeanette C Papp; Charlyn J Suarez; Toni Whistler; Mangalathu S Rajeevan; Suzanne D Vernon; Steve Horvath
Integrated weighted gene co-expression network analysis with an application to chronic fatigue syndrome.
BMC systems biology 2008;2():95.
2008: Yohan Lee; Adrienne C Scheck; Timothy F Cloughesy; Albert Lai; Jun Dong; Haumith K Farooqi; Linda M Liau; Steve Horvath; Paul S Mischel; Stanley F Nelson
Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age.
BMC medical genomics 2008;1():52.
2008: Steve Horvath; Jun Dong
Geometric interpretation of gene coexpression network analysis.
PLoS computational biology 2008;4(8):e1000117.
2008: Jason E Aten; Tova F Fuller; Aldons J Lusis; Steve Horvath
Using genetic markers to orient the edges in quantitative trait networks: the NEO software.
BMC systems biology 2008;2():34.
2008: David Seligson; Sigrid A Rajasekaran; Hong Yu; Xueli Liu; Mervi Eeva; Sheila Tze; William Ball; Steve Horvath; Jean B deKernion; Ayyappan K Rajasekaran
Na,K-adenosine triphosphatase alpha1-subunit predicts survival of renal clear cell carcinoma.
The Journal of urology 2008;179(1):338-45.
2008: Ichiro Nakano; Michael Masterman-Smith; Kuniyasu Saigusa; Andres A Paucar; Steve Horvath; Lorelei Shoemaker; Momoko Watanabe; Alejandra Negro; ruchi bajpai; Amy Howes; Vincent Lelievre; James A Waschek; Jorge A Lazareff; William A Freije; Linda M Liau; Richard J Gilbertson; Timothy F Cloughesy; Daniel Geschwind; Stanley F Nelson; Paul S Mischel; Alexey V Terskikh; Harley I Kornblum
Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells.
Journal of neuroscience research 2008;86(1):48-60.
2007: David Seligson; Fumiya Hongo; Sara Huerta-Yepez; Yoichi Mizutani; Tsuneharu Miki; Hong Yu; Steve Horvath; David Chia; Lee Goodglick; Benjamin Bonavida
Expression of X-linked inhibitor of apoptosis protein is a strong predictor of human prostate cancer recurrence.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(20):6056-63.
2007: Tova F Fuller; Anatole Ghazalpour; Jason E Aten; Thomas A Drake; Aldons J Lusis; Steve Horvath
Weighted gene coexpression network analysis strategies applied to mouse weight.
Mammalian genome : official journal of the International Mammalian Genome Society 2007;18(6-7):463-72.
2007: Lola Rahib; Nicole K MacLennan; Steve Horvath; James C Liao; Katrina M Dipple
Glycerol kinase deficiency alters expression of genes involved in lipid metabolism, carbohydrate metabolism, and insulin signaling.
European journal of human genetics : EJHG 2007;15(6):646-57.
2007: Marc R J Carlson; Whitney B Pope; Steve Horvath; Jerome G Braunstein; Phioanh Nghiemphu; Cho-Lea Tso; Ingo K Mellinghoff; Albert Lai; Linda M Liau; Paul S Mischel; Jun Dong; Stanley F Nelson; Timothy F Cloughesy
Relationship between survival and edema in malignant gliomas: role of vascular endothelial growth factor and neuronal pentraxin 2.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(9):2592-8.
2007: C Daniel Eller; Moira Regelson; Barry Merriman; Stan Nelson; Steve Horvath; York Marahrens
Repetitive sequence environment distinguishes housekeeping genes.
Gene 2007;390(1-2):153-65.
2007: Ai Li; Steve Horvath
Network neighborhood analysis with the multi-node topological overlap measure.
Bioinformatics (Oxford, England) 2007;23(2):222-31.
2007: Peter Langfelder; Steve Horvath
Eigengene networks for studying the relationships between co-expression modules.
BMC systems biology 2007;1():54.
2007: Ke Wei Gong; Wei Zhao; Ning Li; Berenice Barajas; Michael T Kleinman; Constantinos Sioutas; Steve Horvath; Aldons J Lusis; Andre E Nel; Jesus A Araujo
Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells.
Genome biology 2007;8(7):R149.
2007: Jun Dong; Steve Horvath
Understanding network concepts in modules.
BMC systems biology 2007;1():24.
2006: Steve Horvath; Bin Zhang; M Carlson; Kan V Lu; Shaojun Zhu; Felciano Ramon; M F Laurance; W Zhao; S Qi; Z Chen; Y Lee; A C Scheck; Linda M Liau; Hong Wu; Daniel Geschwind; P G Febbo; Harley I Kornblum; Timothy F Cloughesy; Stanley F Nelson; Paul S Mischel
Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(46):17402-7.
2006: Peter Gargalovic; Minori Imura; Bin Zhang; Nima M Gharavi; Michael Clark; Joanne Pagnon; Wen-Pin Yang; Aiqing He; Amy Truong; Shilpa Patel; Stanley F Nelson; Steve Horvath; Judith A Berliner; Todd G Kirchgessner; Aldons J Lusis
Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(34):12741-6.
2006: Anatole Ghazalpour; Sudheer Doss; Bin Zhang; Susanna Wang; Christopher Plaisier; Ruth Castellanos; Alec Brozell; Eric E Schadt; Thomas A Drake; Aldons J Lusis; Steve Horvath
Integrating genetic and network analysis to characterize genes related to mouse weight.
PLoS genetics 2006;2(8):e130.
2006: John S Lam; David Seligson; Hong Yu; Ai Li; Mervi Eeva; Allan J Pantuck; Gang Zeng; Steve Horvath; Arie S Belldegrun
Flap endonuclease 1 is overexpressed in prostate cancer and is associated with a high Gleason score.
BJU international 2006;98(2):445-51.
2006: Sven Bocklandt; Steve Horvath; Eric Vilain; Dean H Hamer
Extreme skewing of X chromosome inactivation in mothers of homosexual men.
Human genetics 2006;118(6):691-4.
2006: Nicole K MacLennan; Lola Rahib; Cynthia Shin; Zixing Fang; Steve Horvath; Jason Dean; James C Liao; Edward R B McCabe; Katrina M Dipple
Targeted disruption of glycerol kinase gene in mice: expression analysis in liver shows alterations in network partners related to glycerol kinase activity.
Human molecular genetics 2006;15(3):405-15.
2006: Marc R J Carlson; Bin Zhang; Zixing Fang; Paul S Mischel; Steve Horvath; Stanley F Nelson
Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks.
BMC genomics 2006;7():40.
2006: Moira Regelson; C Daniel Eller; Steve Horvath; York Marahrens
A link between repetitive sequences and gene replication time.
Cytogenetic and genome research 2006;112(3-4):184-93.
2005: Yan Ouyang; Jennifer L Salstrom; Silvia Diaz-Perez; Shareef A Nahas; Youko Matsuno; David Dawson; Michael A Teitell; Steve Horvath; Arthur D Riggs; Richard A Gatti; York Marahrens
Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.
Biochemical and biophysical research communications 2005;337(3):875-80.
2005: Ingo K Mellinghoff; Maria Y Wang; Igor Vivanco; Daphne A Haas-Kogan; Shaojun Zhu; Ederlyn Q Dia; Kan V Lu; Koji Yoshimoto; Julie H Y Huang; Dennis J Chute; Bridget L Riggs; Steve Horvath; Linda M Liau; Webster K Cavenee; P Nagesh Rao; Rameen Beroukhim; Timothy C Peck; Jeffrey C Lee; William R Sellers; David Stokoe; Michael Prados; Timothy F Cloughesy; Charles L Sawyers; Paul S Mischel
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.
The New England journal of medicine 2005;353(19):2012-24.
2005: David Seligson; Steve Horvath; Sara Huerta-Yepez; Stephanie Hanna; Hermes Garban; Alice Roberts; Tao Shi; Xueli Liu; David Chia; Lee Goodglick; Benjamin Bonavida
Expression of transcription factor Yin Yang 1 in prostate cancer.
International journal of oncology 2005;27(1):131-41.
2005: David Seligson; Steve Horvath; Tao Shi; Hong Yu; Sheila Tze; Michael Grunstein; Siavash K Kurdistani
Global histone modification patterns predict risk of prostate cancer recurrence.
Nature 2005;435(7046):1262-6.
2005: John S Lam; Oleg Shvarts; Jonathan W Said; Allan J Pantuck; David Seligson; Michael E Aldridge; Matthew H T Bui; Xueli Liu; Steve Horvath; Robert A Figlin; Arie S Belldegrun
Clinicopathologic and molecular correlations of necrosis in the primary tumor of patients with renal cell carcinoma.
Cancer 2005;103(12):2517-25.
2005: Hyung L Kim; David Seligson; Xueli Liu; Nicolette K Janzen; Matthew H T Bui; Hong Yu; Tao Shi; Arie S Belldegrun; Steve Horvath; Robert A Figlin
Using tumor markers to predict the survival of patients with metastatic renal cell carcinoma.
The Journal of urology 2005;173(5):1496-501.
2005: John S Lam; Joyce Yamashiro; I Peter Shintaku; Robert L Vessella; Robert B Jenkins; Steve Horvath; Jonathan W Said; Robert E Reiter
Prostate stem cell antigen is overexpressed in prostate cancer metastases.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2591-6.
2005: Tao Shi; David Seligson; Arie S Belldegrun; Aarno Palotie; Steve Horvath
Tumor classification by tissue microarray profiling: random forest clustering applied to renal cell carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(4):547-57.
2005: Oleg Shvarts; David Seligson; John Lam; Tao Shi; Steve Horvath; Robert Figlin; Arie Belldegrun; Allan J Pantuck
p53 is an independent predictor of tumor recurrence and progression after nephrectomy in patients with localized renal cell carcinoma.
The Journal of urology 2005;173(3):725-8.
2005: Bin Zhang; Steve Horvath
A general framework for weighted gene co-expression network analysis.
Statistical applications in genetics and molecular biology 2005;4():Article17.
2004: George V Thomas; Steve Horvath; Bradley L Smith; Katherine Crosby; Lori A Lebel; Matthew Schrage; Jonathan Said; Jean de Kernion; Robert E Reiter; Charles L Sawyers
Antibody-based profiling of the phosphoinositide 3-kinase pathway in clinical prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8351-6.
2004: Isla P Garraway; David Seligson; Jonathan Said; Steve Horvath; Robert E Reiter
Trefoil factor 3 is overexpressed in human prostate cancer.
The Prostate 2004;61(3):209-14.
2004: William A Freije; F Edmundo Castro-Vargas; Zixing Fang; Steve Horvath; Timothy F Cloughesy; Linda M Liau; Paul S Mischel; Stanley F Nelson
Gene expression profiling of gliomas strongly predicts survival.
Cancer research 2004;64(18):6503-10.
2004: Hyung L Kim; David Seligson; Xueli Liu; Nicolette K Janzen; Matthew H T Bui; Hong Yu; Tao Shi; Robert A Figlin; Steve Horvath; Arie S Belldegrun
Using protein expressions to predict survival in clear cell renal carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(16):5464-71.
2004: Xueli Liu; Vladimir Minin; Yunda Huang; David Seligson; Steve Horvath
Statistical methods for analyzing tissue microarray data.
Journal of biopharmaceutical statistics 2004;14(3):671-85.
2004: Matthew H T Bui; Harri Visapaa; David Seligson; Hyung Kim; Ken-Ryu Han; Yunda Huang; Steve Horvath; Eric J Stanbridge; Aarno Palotie; Robert A Figlin; Arie S Belldegrun
Prognostic value of carbonic anhydrase IX and KI67 as predictors of survival for renal clear cell carcinoma.
The Journal of urology 2004;171(6 Pt 1):2461-6.
2004: David Seligson; Allan J Pantuck; Xueli Liu; Yunda Huang; Steve Horvath; Matthew H T Bui; Ken-Ryu Han; Adrian J L Correa; Mervi Eeva; Sheila Tze; Arie S Belldegrun; Robert A Figlin
Epithelial cell adhesion molecule (KSA) expression: pathobiology and its role as an independent predictor of survival in renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2659-69.
2004: Ken-Ryu Han; David Seligson; Xueli Liu; Steve Horvath; Peter Shintaku; George V Thomas; Jonathan W Said; Robert E Reiter
Prostate stem cell antigen expression is associated with gleason score, seminal vesicle invasion and capsular invasion in prostate cancer.
The Journal of urology 2004;171(3):1117-21.
2004: Steve Horvath; Xin Xu; Stephen L Lake; Edwin K Silverman; Scott Weiss; Nan M Laird
Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics.
Genetic epidemiology 2004;26(1):61-9.
2003: Phoebe Dewing; Tao Shi; Steve Horvath; Eric Vilain
Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation.
Brain research. Molecular brain research 2003;118(1-2):82-90.
2003: Peter Kraft; Steve Horvath
The genetics of gene expression and gene mapping.
Trends in biotechnology 2003;21(9):377-8.
2003: Elena Allen; Steve Horvath; Frances Tong; Peter Kraft; Elizabeth Spiteri; Arthur D Riggs; York Marahrens
High concentrations of long interspersed nuclear element sequence distinguish monoallelically expressed genes.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9940-5.
2003: Ruty Shai; Tao Shi; Thomas J Kremen; Steve Horvath; Linda M Liau; Timothy F Cloughesy; Paul S Mischel; Stanley F Nelson
Gene expression profiling identifies molecular subtypes of gliomas.
Oncogene 2003;22(31):4918-23.
2003: Paul S Mischel; Ruty Shai; Tao Shi; Steve Horvath; Kan V Lu; Gheeyoung Choe; David Seligson; Thomas J Kremen; Aarno Palotie; Linda M Liau; Timothy F Cloughesy; Stanley F Nelson
Identification of molecular subtypes of glioblastoma by gene expression profiling.
Oncogene 2003;22(15):2361-73.
2003: Cromwell Espineda; David Seligson; William James Ball; JianYu Rao; Aarno Palotie; Steve Horvath; Yunda Huang; Tao Shi; Ayyappan K Rajasekaran
Analysis of the Na,K-ATPase alpha- and beta-subunit expression profiles of bladder cancer using tissue microarrays.
Cancer 2003;97(8):1859-68.
2003: Harri Visapää; Matthew H T Bui; Yunda Huang; David Seligson; Henry Tsai; Allan J Pantuck; Robert Figlin; Jian Yu Rao; Arie Belldegrun; Steve Horvath; Aarno Palotie
Correlation of Ki-67 and gelsolin expression to clinical outcome in renal clear cell carcinoma.
Urology 2003;61(4):845-50.
2003: Stephen J Freedland; David Seligson; Alvin Y Liu; Allan J Pantuck; Sun H Paik; Steve Horvath; Jeffrey A Wieder; Amnon Zisman; David Nguyen; Cho-Lea Tso; Aarno V Palotie; Arie S Belldegrun
Loss of CD10 (neutral endopeptidase) is a frequent and early event in human prostate cancer.
The Prostate 2003;55(1):71-80.
2003: Harri Visapää; David Seligson; Yunda Huang; Jian Yu Rao; Arie Belldegrun; Steve Horvath; Aarno Palotie
Ki67, gelsolin and PTEN expression in sarcomatoid renal tumors.
Urological research 2003;30(6):387-9.
2003: Matthew H T Bui; David Seligson; Ken-Ryu Han; Allan J Pantuck; Frederick J Dorey; Yunda Huang; Steve Horvath; Bradley C Leibovich; Shefali Chopra; Shu-Yuan Liao; Eric J Stanbridge; Michael I Lerman; Aarno Palotie; Robert A Figlin; Arie S Belldegrun
Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):802-11.
2002: Hisamitsu Ide; David Seligson; Sanaz Memarzadeh; Li Xin; Steve Horvath; Purnima Dubey; Maryann B Flick; Barry M Kacinski; Aarno Palotie; Owen N Witte
Expression of colony-stimulating factor 1 receptor during prostate development and prostate cancer progression.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14404-9.
2002: JianYu Rao; David Seligson; Harri Visapaa; Steve Horvath; Mervi Eeva; Kia Michel; Allan J Pantuck; Arie Belldegrun; Aarno Palotie
Tissue microarray analysis of cytoskeletal actin-associated biomarkers gelsolin and E-cadherin in urothelial carcinoma.
Cancer 2002;95(6):1247-57.
2001: Steve Horvath; E Wei; Xiping Xu; Lyle Palmer; M Baur
Family-based association test method: age of onset traits and covariates.
Genetic epidemiology 2001;21 Suppl 1():S403-8.