FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Laura Attardi

Research Profile

Living Beings

Chemicals & Drugs

Genes & Molecular Sequences

Physiology

Disorders

Anatomy

Co-author Network

Publications

TOP 3
Daniela Kenzelmann Broz; Arend Sidow; Stephano Spano Mello; Kathryn T Bieging; Colleen A Brady; Rachel Dusek; Dadi Jiang; Laura D Attardi
Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses.
Laura D Attardi; Julien Sage
RB goes mitochondrial.
Christina S Kong; Shirley Kwok; Catherine M Nguyen; Laura D Attardi; Veronica G Beaudry; Hongbin Cao; Richard C Jordan; Quynh-Thu Le
Loss of the p53/p63 target PERP is an early event in oral carcinogenesis and correlates with higher rate of local relapse.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Laura Attardi (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Daniela Kenzelmann Broz; Arend Sidow; Stephano Spano Mello; Kathryn T Bieging; Colleen A Brady; Rachel Dusek; Dadi Jiang; Laura D Attardi
Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses.
Genes & development 2013;27(9):1016-31.
2013: Laura D Attardi; Julien Sage
RB goes mitochondrial.
Genes & development 2013;27(9):975-9.
2013: Christina S Kong; Shirley Kwok; Catherine M Nguyen; Laura D Attardi; Veronica G Beaudry; Hongbin Cao; Richard C Jordan; Quynh-Thu Le
Loss of the p53/p63 target PERP is an early event in oral carcinogenesis and correlates with higher rate of local relapse.
Oral surgery, oral medicine, oral pathology and oral radiology 2013;115(1):95-103.
2012: Kathryn T Bieging; Laura D Attardi
Deconstructing p53 transcriptional networks in tumor suppression.
Trends in cell biology 2012;22(2):97-106.
2012: Sylvain Baron; Anabel Hoang; Hannes Vogel; Laura D Attardi
Unimpaired skin carcinogenesis in Desmoglein 3 knockout mice.
PloS one 2012;7(11):e50024.
2012: Rachel Dusek; Hannes Vogel; Sylvain Baron; Jamie L Bascom; Mina J Bissell; Alexander D Borowsky; Laura D Attardi
Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer.
Breast cancer research : BCR 2012;14(2):R65.
2011: Dadi Jiang; Thomas M Johnson; Eunice Y Lee; Eunice J Park; Matthew P Scott; Colleen A Brady; Laura D Attardi
Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(41):17123-8.
2011: Valerie Renault; E E Santo; P U Thekkat; O S Venturelli; H Vogel; J L White; Z Xuan; M Q Zhang; K L Hoang; T M Johnson; D Kenzelmann Broz; P R Oskoui; Laura D Attardi; C A Brady; Anne Brunet
The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.
Oncogene 2011;30(29):3207-21.
2011: Colleen A Brady; Dadi Jiang; Stephano S Mello; Thomas M Johnson; Lesley A Jarvis; Margaret M Kozak; Shashwati Basak; Eunice J Park; Margaret E McLaughlin; Anthony N Karnezis; Daniela Kenzelmann Broz; Laura D Attardi
Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression.
Cell 2011;145(4):571-83.
2011: Rachel Dusek; Laura D Attardi
Desmosomes: new perpetrators in tumour suppression.
Nature reviews. Cancer 2011;11(5):317-23.
2010: Veronica G Beaudry; Dadi Jiang; Rachel Dusek; Eunice J Park; Stevan Knezevich; Katie Ridd; Hannes Vogel; Boris C Bastian; Laura D Attardi
Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis.
PLoS genetics 2010;6(10):e1001168.
2010: Colleen A Brady; Laura D Attardi
p53 at a glance.
Journal of cell science 2010;123(Pt 15):2527-32.
2010: Daniela Kenzelmann Broz; Laura D Attardi
In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models.
Carcinogenesis 2010;31(8):1311-8.
2010: Veronica G Beaudry; Rebecca A Ihrie; Suzanne B R Jacobs; Bichchau Nguyen; Navneeta Pathak; Eunice Park; Laura D Attardi
Loss of the desmosomal component perp impairs wound healing in vivo.
Dermatology research and practice 2010;2010():759731.
2009: Mary Fete; Hans vanBokhoven; Suzanne E Clements; Frank McKeon; Dennis R Roop; Maranke I Koster; Caterina Missero; Laura D Attardi; Vivian A Lombillo; Edward Ratovitski; Meena Julapalli; Derek Ruths; Virginia P Sybert; Elaine C Siegfried; Alanna F Bree
International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome.
American journal of medical genetics. Part A 2009;149A(9):1885-93.
2009: Veronica G Beaudry; Navneeta Pathak; Maranke I Koster; Laura D Attardi
Differential PERP regulation by TP63 mutants provides insight into AEC pathogenesis.
American journal of medical genetics. Part A 2009;149A(9):1952-7.
2009: Veronica G Beaudry; Laura D Attardi
SKP-ing TAp63: stem cell depletion, senescence, and premature aging.
Cell stem cell 2009;5(1):1-2.
2009: Bichchau Nguyen; Rachel Dusek; Veronica G Beaudry; M Peter Marinkovich; Laura D Attardi
Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies.
The Journal of investigative dermatology 2009;129(7):1710-8.
2008: Kelly A McGowan; Jun Z Li; Christopher Park; Veronica Beaudry; Holly K Tabor; Amit J Sabnis; Weibin Zhang; Helmut Fuchs; Martin Hrabé De Angelis; Richard Myers; Laura D Attardi; Gregory S Barsh
Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects.
Nature genetics 2008;40(8):963-70.
2008: Shashwati Basak; Suzanne B R Jacobs; Adam J Krieg; Navneeta Pathak; Qi Zeng; Philipp Kaldis; Amato J Giaccia; Laura D Attardi
The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation.
Molecular cell 2008;30(3):303-14.
2008: Thomas M Johnson; Kristin Meade; Navneeta Pathak; Michelle R Marques; Laura D Attardi
Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(4):1215-20.
2007: S B R Jacobs; Shashwati Basak; John I Murray; N Pathak; Laura D Attardi
Siva is an apoptosis-selective p53 target gene important for neuronal cell death.
Cell death and differentiation 2007;14(7):1374-85.
2007: Gregory S Barsh; Laura D Attardi
A healthy tan?
The New England journal of medicine 2007;356(21):2208-10.
2007: Susan W P Wijnhoven; Ewoud N Speksnijder; Xiaoling Liu; Edwin Zwart; Conny Th M vanOostrom; Rudolf B Beems; Esther M Hoogervorst; Mirjam M Schaap; Laura D Attardi; Tyler Jacks; Harry van Steeg; Jos Jonkers; Annemieke de Vries
Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage.
Cancer research 2007;67(10):4648-56.
2007: Danielle K Carroll; Joan S Brugge; Laura D Attardi
p63, cell adhesion and survival.
Cell cycle (Georgetown, Tex.) 2007;6(3):255-61.
2006: Rebecca A Ihrie; R T Bronson; Laura D Attardi
Adult mice lacking the p53/p63 target gene Perp are not predisposed to spontaneous tumorigenesis but display features of ectodermal dysplasia syndromes.
Cell death and differentiation 2006;13(9):1614-8.
2006: Thomas M Johnson; Laura D Attardi
Dissecting p53 tumor suppressor function in vivo through the analysis of genetically modified mice.
Cell death and differentiation 2006;13(6):902-8.
2006: Ester M Hammond; Daniel J Mandell; Ali Salim; Adam J Krieg; Thomas M Johnson; Haider A Shirazi; Laura D Attardi; Amato J Giaccia
Genome-wide analysis of p53 under hypoxic conditions.
Molecular and cellular biology 2006;26(9):3492-504.
2006: Michelle R Marques; Rebecca A Ihrie; Jennifer S Horner; Laura D Attardi
The requirement for perp in postnatal viability and epithelial integrity reflects an intrinsic role in stratified epithelia.
The Journal of investigative dermatology 2006;126(1):69-73.
2005: Laura D Attardi; Lawrence A Donehower
Probing p53 biological functions through the use of genetically engineered mouse models.
Mutation research 2005;576(1-2):4-21.
2005: Michelle R Marques; Jennifer S Horner; Rebecca A Ihrie; Roderick T Bronson; Laura D Attardi
Mice lacking the p53/p63 target gene Perp are resistant to papilloma development.
Cancer research 2005;65(15):6551-6.
2005: Rebecca A Ihrie; Laura D Attardi
A new Perp in the lineup: linking p63 and desmosomal adhesion.
Cell cycle (Georgetown, Tex.) 2005;4(7):873-6.
2005: Steven E Artandi; Laura D Attardi
Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer.
Biochemical and biophysical research communications 2005;331(3):881-90.
2005: Thomas M Johnson; Laura D Attardi
p53QS: an old mutant teaches us new tricks.
Cell cycle (Georgetown, Tex.) 2005;4(6):731-4.
2005: Rebecca A Ihrie; Michelle R Marques; Bichchau T Nguyen; Jennifer S Horner; Cristian Papazoglu; Roderick T Bronson; Alea A Mills; Laura D Attardi
Perp is a p63-regulated gene essential for epithelial integrity.
Cell 2005;120(6):843-56.
2005: J Martin Brown; Laura D Attardi
The role of apoptosis in cancer development and treatment response.
Nature reviews. Cancer 2005;5(3):231-7.
2005: Thomas M Johnson; Ester M Hammond; Amato J Giaccia; Laura D Attardi
The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality.
Nature genetics 2005;37(2):145-52.
2005: Laura D Attardi
The role of p53-mediated apoptosis as a crucial anti-tumor response to genomic instability: lessons from mouse models.
Mutation research 2005;569(1-2):145-57.
2004: Shelly Beer; Anders Zetterberg; Rebecca A Ihrie; Ryan A McTaggart; Qiwei Yang; Nicole Bradon; Constadina Arvanitis; Laura D Attardi; Sandy Feng; Boris Ruebner; Robert Cardiff; Dean W Felsher
Developmental context determines latency of MYC-induced tumorigenesis.
PLoS biology 2004;2(11):e332.
2004: Wendy Bruins; Edwin Zwart; Laura D Attardi; Tomoo Iwakuma; Esther M Hoogervorst; Rudolf B Beems; Barbara Miranda; Conny Th M van Oostrom; Jolanda van den Berg; Gerard van den Aardweg; Guillermina Lozano; Harry van Steeg; Tyler Jacks; Annemieke de Vries
Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.
Molecular and cellular biology 2004;24(20):8884-94.
2004: Rebecca A Ihrie; Laura D Attardi
Perp-etrating p53-dependent apoptosis.
Cell cycle (Georgetown, Tex.) 2004;3(3):267-9.
2004: Laura D Attardi; Annemieke de Vries; Tyler Jacks
Activation of the p53-dependent G1 checkpoint response in mouse embryo fibroblasts depends on the specific DNA damage inducer.
Oncogene 2004;23(4):973-80.
2004: Laura D Attardi; Ronald A DePinho
Conquering the complexity of p53.
Nature genetics 2004;36(1):7-8.
2003: Elizabeth E Reczek; Elsa R Flores; Alice S Tsay; Laura D Attardi; Tyler Jacks
Multiple response elements and differential p53 binding control Perp expression during apoptosis.
Molecular cancer research : MCR 2003;1(14):1048-57.
2003: Rebecca A Ihrie; Elizabeth E Reczek; Jennifer S Horner; Leili Khachatrian; Julien Sage; Tyler Jacks; Laura D Attardi
Perp is a mediator of p53-dependent apoptosis in diverse cell types.
Current biology : CB 2003;13(22):1985-90.
2000: Julien Sage; GJ Mulligan; Laura D Attardi; A Miller; Shuyan Chen; Bart Williams; E Theodorou; Tyler Jacks
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.
Genes & development 2000;14(23):3037-50.
2000: Laura D Attardi; Elizabeth E Reczek; C Cosmas; E G Demicco; Mila E McCurrach; Scott W Lowe; Tyler Jacks
PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family.
Genes & development 2000;14(6):704-18.
1999: Laura D Attardi; Tyler Jacks
The role of p53 in tumour suppression: lessons from mouse models.
Cellular and molecular life sciences : CMLS 1999;55(1):48-63.
1997: J M Jones; Laura D Attardi; L A Godley; Rodolfo Laucirica; Daniel Medina; Tyler Jacks; Harold Varmus; Lawrence A Donehower
Absence of p53 in a mouse mammary tumor model promotes tumor cell proliferation without affecting apoptosis.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(8):829-38.
1996: Laura D Attardi; Scott W Lowe; James Brugarolas; Tyler Jacks
Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis.
The EMBO journal 1996;15(14):3693-701.
1995: V P Sah; Laura D Attardi; G J Mulligan; Bart Williams; Roderick T Bronson; Tyler Jacks
A subset of p53-deficient embryos exhibit exencephaly.
Nature genetics 1995;10(2):175-80.
1994: J L Chen; Laura D Attardi; C P Verrijzer; K Yokomori; Robert Tjian
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators.
Cell 1994;79(1):93-105.
1993: Laura D Attardi; D Von Seggern; Robert Tjian
Ectopic expression of wild-type or a dominant-negative mutant of transcription factor NTF-1 disrupts normal Drosophila development.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10563-7.
1993: Laura D Attardi; Robert Tjian
Drosophila tissue-specific transcription factor NTF-1 contains a novel isoleucine-rich activation motif.
Genes & development 1993;7(7B):1341-53.
1990: G L Yu; J D Bradley; Laura D Attardi; Elizabeth H Blackburn
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs.
Nature 1990;344(6262):126-32.
1989: Brian David Dynlacht; Laura D Attardi; A Admon; M Freeman; Robert Tjian
Functional analysis of NTF-1, a developmentally regulated Drosophila transcription factor that binds neuronal cis elements.
Genes & development 1989;3(11):1677-88.