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Ludwig Hothorn

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TOP 3
C Frömke; Ludwig A Hothorn; J Onken; F Sczesny; M Schneider
Analytical method transfer: improving interpretability with ratio-based statistical approaches.
Philip Pallmann; Kai U Priesnitz; Frank Schaarschmidt; Christiane Fischer; Ludwig A Hothorn; Heiko Nacke; Nicholas J Schork
Assessing group differences in biodiversity by simultaneously testing a user-defined selection of diversity indices.
Esther Herberich; Ludwig A Hothorn
Statistical evaluation of mortality in long-term carcinogenicity bioassays using a Williams-type procedure.

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All Publications

2013: C Frömke; Ludwig A Hothorn; J Onken; F Sczesny; M Schneider
Analytical method transfer: improving interpretability with ratio-based statistical approaches.
Journal of pharmaceutical and biomedical analysis 2013;74():186-93.
2012: Philip Pallmann; Kai U Priesnitz; Frank Schaarschmidt; Christiane Fischer; Ludwig A Hothorn; Heiko Nacke; Nicholas J Schork
Assessing group differences in biodiversity by simultaneously testing a user-defined selection of diversity indices.
Molecular ecology resources 2012;12(6):1068-78.
2012: Esther Herberich; Ludwig A Hothorn
Statistical evaluation of mortality in long-term carcinogenicity bioassays using a Williams-type procedure.
Regulatory toxicology and pharmacology : RTP 2012;64(1):26-34.
2012: Gabriela Senti; Ozge Soyer; Martin Steiner; Christine Tivig; Marianne van Hage; Anna Zaleska; Daniela Kuster; Julia M Martinez-Gomez; Horst Rose; Cezmi A. Akdis; Mübeccel Akdis; Reto Crameri; Nicole Graf; Hans Grönlund; Ludwig A Hothorn; Pål Johansen; Thomas M Kündig
Intralymphatic immunotherapy for cat allergy induces tolerance after only 3 injections.
The Journal of allergy and clinical immunology 2012;129(5):1290-6.
2012: Sebastian Hoffmann; Ludwig A Hothorn; André Kleensang; Pascal Phrakonkham; Masaya Suzuki; Lutz Edler; Daniel Gerhard
Two new approaches to improve the analysis of BALB/c 3T3 cell transformation assay data.
Mutation research 2012;744(1):36-41.
2012: Ludwig A Hothorn; Ondrej Libiger; Daniel Gerhard
Model-specific tests on variance heterogeneity for detection of potentially interacting genetic loci.
BMC genetics 2012;13():59.
2012: Frank Konietschke; Ondrej Libiger; Ludwig A Hothorn
Nonparametric evaluation of quantitative traits in population-based association studies when the genetic model is unknown.
PloS one 2012;7(2):e31242.
2011: Ludwig A Hothorn; Gemechis D Djira
A ratio-to-control Williams-type test for trend.
Pharmaceutical statistics 2011;10(4):289-92.
2010: Ludwig A Hothorn; Hans-Werner Vohr
Statistical evaluation of the Local Lymph Node Assay.
Regulatory toxicology and pharmacology : RTP 2010;56(3):352-6.
2010: Ludwig A Hothorn; Martin Sill; Frank Schaarschmidt
Evaluation of incidence rates in pre-clinical studies using a Williams-type procedure.
The international journal of biostatistics 2010;6(1):Article 15.
2010: Daniel Gerhard; Ludwig A Hothorn
Rank transformation in Haseman-Elston regression using scores for location-scale alternatives.
Human heredity 2010;69(3):143-51.
2010: Hanne Zimmermann; Daniel Gerhard; Theo Dingermann; Ludwig A Hothorn
Statistical aspects of design and validation of microtitre-plate-based linear and non-linear parallel in vitro bioassays.
Biotechnology journal 2010;5(1):62-74.
2009: Ludwig A Hothorn; D Gerhard; M Hofmann
Parametric and non-parametric prediction intervals based phase II control charts for repeated bioassay data.
Biologicals : journal of the International Association of Biological Standardization 2009;37(5):323-30.
2009: Ludwig A Hothorn; Torsten Hothorn
Order-restricted scores test for the evaluation of population-based case-control studies when the genetic model is unknown.
Biometrical journal. Biometrische Zeitschrift 2009;51(4):659-69.
2009: Ludwig A Hothorn; Daniel Gerhard
Statistical evaluation of the in vivo micronucleus assay.
Archives of toxicology 2009;83(6):625-34.
2009: Ludwig A Hothorn; Michael Vaeth; Torsten Hothorn
Trend tests for the evaluation of exposure-response relationships in epidemiological exposure studies.
Epidemiologic perspectives & innovations : EP+I 2009;6():1.
2009: Frank Schaarschmidt; Egbert Biesheuvel; Ludwig A Hothorn
Asymptotic simultaneous confidence intervals for many-to-one comparisons of binary proportions in randomized clinical trials.
Journal of biopharmaceutical statistics 2009;19(2):292-310.
2008: Mario Hasler; Ludwig A Hothorn
Multiple contrast tests in the presence of heteroscedasticity.
Biometrical journal. Biometrische Zeitschrift 2008;50(5):793-800.
2008: Frank Schaarschmidt; Martin Sill; Ludwig A Hothorn
Approximate simultaneous confidence intervals for multiple contrasts of binomial proportions.
Biometrical journal. Biometrische Zeitschrift 2008;50(5):782-92.
2008: Mario Hasler; Richardus Vonk; Ludwig A Hothorn
Assessing non-inferiority of a new treatment in a three-arm trial in the presence of heteroscedasticity.
Statistics in medicine 2008;27(4):490-503.
2008: Gemechis D Djira; Ludwig A Hothorn; Yi Tsong
Equivalence tests for shelf life and average drug content in stability studies.
Journal of biopharmaceutical statistics 2008;18(5):985-95.
2008: Frank Schaarschmidt; Martin Sill; Ludwig A Hothorn
Poly-k-trend tests for survival adjusted analysis of tumor rates formulated as approximate multiple contrast test.
Journal of biopharmaceutical statistics 2008;18(5):934-48.
2008: Ludwig A Hothorn; Mario Hasler
Proof of hazard and proof of safety in toxicological studies using simultaneous confidence intervals for differences and ratios to control.
Journal of biopharmaceutical statistics 2008;18(5):915-33.
2008: Cornelia Frömke; Ludwig A Hothorn; Siegfried Kropf
Nonparametric relevance-shifted multiple testing procedures for the analysis of high-dimensional multivariate data with small sample sizes.
BMC bioinformatics 2008;9():54.
2007: Ludwig A Hothorn
How to deal with multiple treatment or dose groups in randomized clinical trials?
Fundamental & clinical pharmacology 2007;21(2):137-54.
2006: Achim Gathmann; Ludger Wirooks; Ludwig A Hothorn; Detlef Bartsch; Ingolf Schuphan
Impact of Bt maize pollen (MON810) on lepidopteran larvae living on accompanying weeds.
Molecular ecology 2006;15(9):2677-85.
2006: Gemechis Dilba; Frank Bretz; Ludwig A Hothorn; Volker Guiard
Power and sample size computations in simultaneous tests for non-inferiority based on relative margins.
Statistics in medicine 2006;25(7):1131-47.
2006: Ludwig A Hothorn; Regina Oberdoerfer
Statistical analysis used in the nutritional assessment of novel food using the proof of safety.
Regulatory toxicology and pharmacology : RTP 2006;44(2):125-35.
2006: Ludwig A Hothorn
Multiple comparisons and multiple contrasts in randomized dose-response trials--confidence interval oriented approaches.
Journal of biopharmaceutical statistics 2006;16(5):711-31.
2004: G Dilba; Frank Bretz; V Guiard; Ludwig A Hothorn
Simultaneous confidence intervals for ratios with applications to the comparison of several treatments with a control.
Methods of information in medicine 2004;43(5):465-9.
2003: Egbert H E Biesheuvel; Ludwig A Hothorn
Protocol designed subgroup analyses in multiarmed clinical trials: multiplicity aspects.
Journal of biopharmaceutical statistics 2003;13(4):663-73.
2003: Ludwig A Hothorn; Frank Bretz
Dose-response and thresholds in mutagenicity studies: a statistical testing approach.
Alternatives to laboratory animals : ATLA 2003;31 Suppl 1():97-103.
2003: Frank Bretz; Ludwig A Hothorn
Statistical analysis of monotone or non-monotone dose-response data from in vitro toxicological assays.
Alternatives to laboratory animals : ATLA 2003;31 Suppl 1():81-96.
2003: Dieter Hauschke; Ludwig A Hothorn
Two-stage testing of safety: a statistical view.
Alternatives to laboratory animals : ATLA 2003;31 Suppl 1():77-80.
2003: Ludwig A Hothorn
Statistics of interlaboratory in vitro toxicological studies.
Alternatives to laboratory animals : ATLA 2003;31 Suppl 1():43-63.
2003: Ludwig A Hothorn; Gernot Wassmer
Analyzing randomized dose finding studies with a primary and a secondary endpoint.
Journal of biopharmaceutical statistics 2003;13(2):301-5.
2003: Frank Bretz; Ludwig A Hothorn; Jason C Hsu
Identifying effective and/or safe doses by stepwise confidence intervals for ratios.
Statistics in medicine 2003;22(6):847-58.
2002: Ludwig A Hothorn
Selected biostatistical aspects of the validation of in vitro toxicological assays.
Alternatives to laboratory animals : ATLA 2002;30 Suppl 2():93-8.
2002: Frank Bretz; Ludwig A Hothorn
Detecting dose-response using contrasts: asymptotic power and sample size determination for binomial data.
Statistics in medicine 2002;21(22):3325-35.
2002: Frieder Bauss; Sigrid Lalla; Richard Endele; Ludwig A Hothorn
Effects of treatment with ibandronate on bone mass, architecture, biomechanical properties, and bone concentration of ibandronate in ovariectomized aged rats.
The Journal of rheumatology 2002;29(10):2200-8.
2001: Frank Bretz; Ludwig A Hothorn
Testing dose-response relationships with a priori unknown, possibly nonmonotone shapes.
Journal of biopharmaceutical statistics 2001;11(3):193-207.
2000: Ludwig A Hothorn; Dieter Hauschke
Identifying the maximum safe dose: a multiple testing approach.
Journal of biopharmaceutical statistics 2000;10(1):15-30.
1998: S Lalla; Ludwig A Hothorn; N Haag; R Bader; Frieder Bauss
Lifelong administration of high doses of ibandronate increases bone mass and maintains bone quality of lumbar vertebrae in rats.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1998;8(2):97-103.