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Ming-Hon Hou

Research Profile

Phenomena

Chemicals & Drugs

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Human Coronavirus 229E

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Surface Plasmon Resonance

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Publications

TOP 3
I-Jung Chen; Yu-Ming Chang; Tai-Huang Huang; Shing-Yen Lin; Stanley Perlman; Yo-Yu Shen; Jeu-Ming P Yuann; Jincun Zhao; Ming-Hon Hou
Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein.
Yu-Sheng Lo; Wen-Hsuan Tseng; Chien-Ying Chuang; Ming-Hon Hou
The structural basis of actinomycin D-binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats.
Yu-Wen Chen; Ming-Hon Hou
The binding of the Co(II) complex of dimeric chromomycin A3 to GC sites with flanking G:G mismatches.

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2013: I-Jung Chen; Yu-Ming Chang; Tai-Huang Huang; Shing-Yen Lin; Stanley Perlman; Yo-Yu Shen; Jeu-Ming P Yuann; Jincun Zhao; Ming-Hon Hou
Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein.
Biochimica et biophysica acta 2013;1834(6):1054-62.
2013: Yu-Sheng Lo; Wen-Hsuan Tseng; Chien-Ying Chuang; Ming-Hon Hou
The structural basis of actinomycin D-binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats.
Nucleic acids research 2013;41(7):4284-94.
2013: Yu-Wen Chen; Ming-Hon Hou
The binding of the Co(II) complex of dimeric chromomycin A3 to GC sites with flanking G:G mismatches.
Journal of inorganic biochemistry 2013;121():28-36.
2013: Shu-Ming Kuo; Siou-Hong Lin; Ming-Hon Hou; Hsiao-Wei Kao; Ching-Ho Wang; Hong-Lin Su
Evolution of infectious bronchitis virus in Taiwan: positively selected sites in the nucleocapsid protein and their effects on RNA-binding activity.
Veterinary microbiology 2013;162(2-4):408-18.
2013: Fang-Ying Liang; Leng-Chieh Lin; Tswen-Kei Tang; Chen-Wen Yao; Tsung-Ho Ying; Yi-Wen Chen; Ming-Hon Hou
Immunoreactivity characterisation of the three structural regions of the human coronavirus OC43 nucleocapsid protein by Western blot: implications for the diagnosis of coronavirus infection.
Journal of virological methods 2013;187(2):413-20.
2013: Chun-Wei Hsu; Chia-Feng Kuo; Show-Mei Chuang; Ming-Hon Hou
Elucidation of the DNA-interacting properties and anticancer activity of a Ni(II)-coordinated mithramycin dimer complex.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2013;26(1):1-12.
2013: Yu-Sheng Lo; Chin-Tien Wang; Shiu-Mei Wang; Ya-Li Chiu; Tai-Huang Huang; Shing-Yen Lin; Ming-Hon Hou
Oligomerization of the carboxyl terminal domain of the human coronavirus 229E nucleocapsid protein.
FEBS letters 2013;587(2):120-7.
2012: Hui-Chen Hung; Chia-Lin Liu; Shau-Hua Ueng; Min-Ying Wang; Su-Ying Wu; Cheng-Wen Yaw; Ming-Yu Fang; Jim-Tong Horng; John T A Hsu; Ming-Hon Hou
Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching.
Analytical chemistry 2012;84(15):6391-9.
2012: Man-Ru Wu; Ya-Lin Lin; Ming-Hon Hou; Chia-Feng Kuo
2,4,5-TMBA, a natural inhibitor of cyclooxygenase-2, suppresses adipogenesis and promotes lipolysis in 3T3-L1 adipocytes.
Journal of agricultural and food chemistry 2012;60(29):7262-9.
2012: Sheng-Yu Wang; Wen-Lin Wu; Jeu-Ming P Yuann; Jeremy J W Chen; Show-Mei Chuang; Yi-Hua Lai; Yueh-Luen Lee; Wang-Lin Su; Ming-Hon Hou
Spermine attenuates the action of the DNA intercalator, actinomycin D, on DNA binding and the inhibition of transcription and DNA replication.
PloS one 2012;7(11):e47101.
2012: Yu-Ming Chang; Cammy K-M Chen; Ming-Hon Hou; Wen-Yih Jeng; Yuan-Chih Chang; Andrew H-J Wang
Functional studies of ssDNA binding ability of MarR family protein TcaR from Staphylococcus epidermidis.
PloS one 2012;7(9):e45665.
2012: Chun-Wei Hsu; Wen-Ling Wu; Show-Mei Chuang; Ming-Hon Hou
The crucial role of divalent metal ions in the DNA-acting efficacy and inhibition of the transcription of dimeric chromomycin A3.
PloS one 2012;7(9):e43792.
2012: Yu-Ming Chang; Cammy K-M Chen; Ming-Hon Hou
Conformational Changes in DNA upon Ligand Binding Monitored by Circular Dichroism.
International journal of molecular sciences 2012;13(3):3394-413.
2005: Tswen-Kei Tang; Mark P-J Wu; Shui-Tein Chen; Ming-Hon Hou; Ming-Hsiang Hong; Fu-Ming Pan; Hui-Ming Yu; Jenn-Han Chen; Chen-Wen Yao; Andrew H-J Wang
Biochemical and immunological studies of nucleocapsid proteins of severe acute respiratory syndrome and 229E human coronaviruses.
Proteomics 2005;5(4):925-37.
2005: Ming-Hon Hou; Andrew H-J Wang
Mithramycin forms a stable dimeric complex by chelating with Fe(II): DNA-interacting characteristics, cellular permeation and cytotoxicity.
Nucleic acids research 2005;33(4):1352-61.
2004: Ming-Hon Hou; Howard Robinson; Yi-Gui Gao; Andrew H-J Wang
Crystal structure of the [Mg2+-(chromomycin A3)2]-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by a metal ion.
Nucleic acids research 2004;32(7):2214-22.
2002: Ming-Hon Hou; Howard Robinson; Yi-Gui Gao; Andrew H-J Wang
Crystal structure of actinomycin D bound to the CTG triplet repeat sequences linked to neurological diseases.
Nucleic acids research 2002;30(22):4910-7.