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Thomas Houslay

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Signal Transduction

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Publications

TOP 3
Tian-Rui Xu; George S Baillie; Narinder Bhari; Thomas M Houslay; Andrew M Pitt; David R Adams; Walter Kolch; Miles D Houslay; Graeme Milligan
Mutations of beta-arrestin 2 that limit self-association also interfere with interactions with the beta2-adrenoceptor and the ERK1/2 MAPKs: implications for beta2-adrenoceptor signalling via the ERK1/2 MAPKs.
K John Smith; George S Baillie; Eva I Hyde; Xiang Li; Thomas M Houslay; Angela McCahill; Allan J Dunlop; Graeme B Bolger; Enno Klussmann; David R Adams; Miles D Houslay
1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1.
George S Baillie; David R Adams; Narinder Bhari; Thomas M Houslay; Suryakiran Vadrevu; Dong Meng; Xiang Li; Allan J Dunlop; Graeme Milligan; Graeme B Bolger; Enno Klussmann; Miles D Houslay
Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays.

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All Publications

2008: Tian-Rui Xu; George S Baillie; Narinder Bhari; Thomas M Houslay; Andrew M Pitt; David R Adams; Walter Kolch; Miles D Houslay; Graeme Milligan
Mutations of beta-arrestin 2 that limit self-association also interfere with interactions with the beta2-adrenoceptor and the ERK1/2 MAPKs: implications for beta2-adrenoceptor signalling via the ERK1/2 MAPKs.
The Biochemical journal 2008;413(1):51-60.
2007: K John Smith; George S Baillie; Eva I Hyde; Xiang Li; Thomas M Houslay; Angela McCahill; Allan J Dunlop; Graeme B Bolger; Enno Klussmann; David R Adams; Miles D Houslay
1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1.
Cellular signalling 2007;19(12):2612-24.
2007: George S Baillie; David R Adams; Narinder Bhari; Thomas M Houslay; Suryakiran Vadrevu; Dong Meng; Xiang Li; Allan J Dunlop; Graeme Milligan; Graeme B Bolger; Enno Klussmann; Miles D Houslay
Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays.
The Biochemical journal 2007;404(1):71-80.
2006: Elaine Huston; Irene Gall; Thomas M Houslay; Miles D Houslay
Helix-1 of the cAMP-specific phosphodiesterase PDE4A1 regulates its phospholipase-D-dependent redistribution in response to release of Ca2+.
Journal of cell science 2006;119(Pt 18):3799-810.
2006: Elaine Huston; Thomas M Houslay; George S Baillie; Miles D Houslay
cAMP phosphodiesterase-4A1 (PDE4A1) has provided the paradigm for the intracellular targeting of phosphodiesterases, a process that underpins compartmentalized cAMP signalling.
Biochemical Society transactions 2006;34(Pt 4):504-9.
2005: Derek A Wallace; Lee Ann Johnston; Elaine Huston; Douglas MacMaster; Thomas M Houslay; York-Fong Cheung; Lachlan Campbell; Jennifer Millen; Robin A Smith; Irene Gall; Richard G Knowles; Michael Sullivan; Miles D Houslay
Identification and characterization of PDE4A11, a novel, widely expressed long isoform encoded by the human PDE4A cAMP phosphodiesterase gene.
Molecular pharmacology 2005;67(6):1920-34.