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Andrew Howard

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TOP 3
Kap Lim; Sadhana Pullalarevu; Karen Talin Surabian; Andrew Howard; Tomohiko Suzuki; John Moult; Osnat Herzberg
Structural basis for the mechanism and substrate specificity of glycocyamine kinase, a phosphagen kinase family member.
Mark A Willis; Zhihao Zhuang; Feng Song; Andrew Howard; Debra Dunaway-Mariano; Osnat Herzberg
Structure of YciA from Haemophilus influenzae (HI0827), a hexameric broad specificity acyl-coenzyme A thioesterase.
Alexey Teplyakov; Kap Lim; Peng-Peng Zhu; Geeta Kapadia; Celia C H Chen; Jennifer Schwartz; Andrew Howard; Prasad T Reddy; Alan Peterkofsky; Osnat Herzberg
Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein.

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All Publications

2010: Kap Lim; Sadhana Pullalarevu; Karen Talin Surabian; Andrew Howard; Tomohiko Suzuki; John Moult; Osnat Herzberg
Structural basis for the mechanism and substrate specificity of glycocyamine kinase, a phosphagen kinase family member.
Biochemistry 2010;49(9):2031-41.
2008: Mark A Willis; Zhihao Zhuang; Feng Song; Andrew Howard; Debra Dunaway-Mariano; Osnat Herzberg
Structure of YciA from Haemophilus influenzae (HI0827), a hexameric broad specificity acyl-coenzyme A thioesterase.
Biochemistry 2008;47(9):2797-805.
2006: Alexey Teplyakov; Kap Lim; Peng-Peng Zhu; Geeta Kapadia; Celia C H Chen; Jennifer Schwartz; Andrew Howard; Prasad T Reddy; Alan Peterkofsky; Osnat Herzberg
Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16218-23.
2006: Celia C H Chen; Ying Han; Weiling Niu; Anna N Kulakova; Andrew Howard; John P Quinn; Debra Dunaway-Mariano; Osnat Herzberg
Structure and kinetics of phosphonopyruvate hydrolase from Variovorax sp. Pal2: new insight into the divergence of catalysis within the PEP mutase/isocitrate lyase superfamily.
Biochemistry 2006;45(38):11491-504.
2006: Natasha Smith; Adrian E Roitberg; Eva Rivera; Andrew Howard; Marcia J Holden; Martin P Mayhew; Salita Kaistha; D Travis Gallagher
Structural analysis of ligand binding and catalysis in chorismate lyase.
Archives of biochemistry and biophysics 2006;445(1):72-80.
2005: Alexey Teplyakov; Sijiu Liu; Zhibing Lu; Andrew Howard; Debra Dunaway-Mariano; Osnat Herzberg
Crystal structure of the petal death protein from carnation flower.
Biochemistry 2005;44(50):16377-84.
2005: Christopher Lehmann; Sadhana Pullalarevu; Wojciech Krajewski; Mark A Willis; Andrey Galkin; Andrew Howard; Osnat Herzberg
Structure of HI0073 from Haemophilus influenzae, the nucleotide-binding domain of a two-protein nucleotidyl transferase.
Proteins 2005;60(4):807-11.
2005: Mark A Willis; Feng Song; Zhihao Zhuang; Wojciech Krajewski; Vani Rao Chalamasetty; Prasad Reddy; Andrew Howard; Debra Dunaway-Mariano; Osnat Herzberg
Structure of YciI from Haemophilus influenzae (HI0828) reveals a ferredoxin-like alpha/beta-fold with a histidine/aspartate centered catalytic site.
Proteins 2005;59(3):648-52.
2005: Kap Lim; Victoria Doseeva; Elif Sarikaya Demirkan; Sadhana Pullalarevu; Wojciech Krajewski; Andrey Galkin; Andrew Howard; Osnat Herzberg
Crystal structure of the YgfY from Escherichia coli, a protein that may be involved in transcriptional regulation.
Proteins 2005;58(3):759-63.
2004: Andrey Galkin; Elif Sarikaya; Christopher Lehmann; Andrew Howard; Osnat Herzberg
X-ray structure of HI0817 from Haemophilus influenzae: protein of unknown function with a novel fold.
Proteins 2004;57(4):874-7.
2004: Kap Lim; Elif Sarikaya; Andrey Galkin; Wojciech Krajewski; Sadhana Pullalarevu; Jae-Ho Shin; Zvi Kelman; Andrew Howard; Osnat Herzberg
Novel structure and nucleotide binding properties of HI1480 from Haemophilus influenzae: a protein with no known sequence homologues.
Proteins 2004;56(3):564-71.
2004: Christopher Lehmann; Victoria Doseeva; Sadhana Pullalarevu; Wojciech Krajewski; Andrew Howard; Osnat Herzberg
YbdK is a carboxylate-amine ligase with a gamma-glutamyl:Cysteine ligase activity: crystal structure and enzymatic assays.
Proteins 2004;56(2):376-83.
2004: Sijiu Liu; Zhibing Lu; Ying Han; Yong Jia; Andrew Howard; Debra Dunaway-Mariano; Osnat Herzberg
Conformational flexibility of PEP mutase.
Biochemistry 2004;43(15):4447-53.
2004: Andrey Galkin; Liudmila Kulakova; Elif Sarikaya; Kap Lim; Andrew Howard; Osnat Herzberg
Structural insight into arginine degradation by arginine deiminase, an antibacterial and parasite drug target.
The Journal of biological chemistry 2004;279(14):14001-8.
2003: Kap Lim; Aleksandra Tempczyk; Nicklas Bonander; John Toedt; Andrew Howard; Edward Eisenstein; Osnat Herzberg
A catalytic mechanism for D-Tyr-tRNATyr deacylase based on the crystal structure of Hemophilus influenzae HI0670.
The Journal of biological chemistry 2003;278(15):13496-502.
2003: Kap Lim; Hong Zhang; Aleksandra Tempczyk; Wojciech Krajewski; Nicklas Bonander; John Toedt; Andrew Howard; Edward Eisenstein; Osnat Herzberg
Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): a cofactor bound at a site formed by a knot.
Proteins 2003;51(1):56-67.
2003: Kap Lim; Aleksandra Tempczyk; James F Parsons; Nicklas Bonander; John Toedt; Zvi Kelman; Andrew Howard; Edward Eisenstein; Osnat Herzberg
Crystal structure of YbaB from Haemophilus influenzae (HI0442), a protein of unknown function coexpressed with the recombinational DNA repair protein RecR.
Proteins 2003;50(2):375-9.
2003: Christopher Lehmann; Kap Lim; Vani Rao Chalamasetty; Wojciech Krajewski; Eugene Melamud; Andrey Galkin; Andrew Howard; Zvi Kelman; Prasad T Reddy; Alexey G Murzin; Osnat Herzberg
The HI0073/HI0074 protein pair from Haemophilus influenzae is a member of a new nucleotidyltransferase family: structure, sequence analyses, and solution studies.
Proteins 2003;50(2):249-60.
2002: Mark A Willis; Wojciech Krajewski; Vani Rao Chalamasetty; Prasad Reddy; Andrew Howard; Osnat Herzberg
Structure of HI1333 (YhbY), a putative RNA-binding protein from Haemophilus influenzae.
Proteins 2002;49(3):423-6.
2002: Celia C H Chen; H Zhang; A D Kim; Andrew Howard; G M Sheldrick; D Mariano-Dunaway; Osnat Herzberg
Degradation pathway of the phosphonate ciliatine: crystal structure of 2-aminoethylphosphonate transaminase.
Biochemistry 2002;41(44):13162-9.
2002: Christopher Lehmann; Kap Lim; John Toedt; Wojciech Krajewski; Andrew Howard; Edward Eisenstein; Osnat Herzberg
Structure of 2C-methyl-D-erythrol-2,4-cyclodiphosphate synthase from Haemophilus influenzae: activation by conformational transition.
Proteins 2002;49(1):135-8.
2002: Osnat Herzberg; Celia C H Chen; Sijiu Liu; Aleksandra Tempczyk; Andrew Howard; Min Wei; Dongmei Ye; Debra Dunaway-Mariano
Pyruvate site of pyruvate phosphate dikinase: crystal structure of the enzyme-phosphonopyruvate complex, and mutant analysis.
Biochemistry 2002;41(3):780-7.
2001: Kap Lim; Hong Zhang; Aleksandra Tempczyk; Nicklas Bonander; John Toedt; Andrew Howard; Edward Eisenstein; Osnat Herzberg
Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine.
Proteins 2001;45(4):397-407.
2001: D Travis Gallagher; Martin P Mayhew; Marcia J Holden; Andrew Howard; K J Kim; Vincent L Vilker
The crystal structure of chorismate lyase shows a new fold and a tightly retained product.
Proteins 2001;44(3):304-11.
2000: C Kendall Stover; Martin P Mayhew; Marcia J Holden; Andrew Howard; D Travis Gallagher
Crystallization and 1.1-A diffraction of chorismate lyase from Escherichia coli.
Journal of structural biology 2000;129(1):96-9.