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Kembra Howdeshell

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TOP 3
Bethany R Hannas; Kembra L Howdeshell; Christy S Lambright; Vickie S Wilson; Johnathan Furr; L Earl Gray
Dose-response assessment of fetal testosterone production and gene expression levels in rat testes following in utero exposure to diethylhexyl phthalate, diisobutyl phthalate, diisoheptyl phthalate, and diisononyl phthalate.
Andrew Hotchkiss; C V Rider; Johnathan Furr; Kembra L Howdeshell; Chad R Blystone; Vickie S Wilson; L Earl Gray
In utero exposure to an AR antagonist plus an inhibitor of fetal testosterone synthesis induces cumulative effects on F1 male rats.
Nigel C Noriega; Kembra L Howdeshell; Johnathan Furr; Christy R Lambright; Vickie S Wilson; L Earl Gray
Pubertal administration of DEHP delays puberty, suppresses testosterone production, and inhibits reproductive tract development in male Sprague-Dawley and Long-Evans rats.

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All Publications

2011: Bethany R Hannas; Kembra L Howdeshell; Christy S Lambright; Vickie S Wilson; Johnathan Furr; L Earl Gray
Dose-response assessment of fetal testosterone production and gene expression levels in rat testes following in utero exposure to diethylhexyl phthalate, diisobutyl phthalate, diisoheptyl phthalate, and diisononyl phthalate.
Toxicological sciences : an official journal of the Society of Toxicology 2011;123(1):206-16.
2010: Andrew Hotchkiss; C V Rider; Johnathan Furr; Kembra L Howdeshell; Chad R Blystone; Vickie S Wilson; L Earl Gray
In utero exposure to an AR antagonist plus an inhibitor of fetal testosterone synthesis induces cumulative effects on F1 male rats.
Reproductive toxicology (Elmsford, N.Y.) 2010;30(2):261-70.
2009: Nigel C Noriega; Kembra L Howdeshell; Johnathan Furr; Christy R Lambright; Vickie S Wilson; L Earl Gray
Pubertal administration of DEHP delays puberty, suppresses testosterone production, and inhibits reproductive tract development in male Sprague-Dawley and Long-Evans rats.
Toxicological sciences : an official journal of the Society of Toxicology 2009;111(1):163-78.
2009: L Earl Gray; Norman J Barlow; Kembra L Howdeshell; Joseph Ostby; Johnathan Furr; Clark L Gray
Transgenerational effects of Di (2-ethylhexyl) phthalate in the male CRL:CD(SD) rat: added value of assessing multiple offspring per litter.
Toxicological sciences : an official journal of the Society of Toxicology 2009;110(2):411-25.
2009: Vickie S Wilson; Christy Lambright; Johnathan Furr; Kembra L Howdeshell; L Earl Gray
The herbicide linuron reduces testosterone production from the fetal rat testis during both in utero and in vitro exposures.
Toxicology letters 2009;186(2):73-7.
2009: Cynthia V Rider; Vickie S Wilson; Kembra L Howdeshell; Andrew Hotchkiss; Johnathan R Furr; Christy R Lambright; L Earl Gray
Cumulative effects of in utero administration of mixtures of "antiandrogens" on male rat reproductive development.
Toxicologic pathology 2009;37(1):100-13.
2008: Kembra L Howdeshell; Cynthia V Rider; Vickie S Wilson; L Earl Gray
Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats.
Environmental research 2008;108(2):168-76.
2008: Kembra L Howdeshell; Vickie S Wilson; Johnathan Furr; Christy R Lambright; Cynthia V Rider; Chad R Blystone; Andrew K Hotchkiss; L Earl Gray
A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner.
Toxicological sciences : an official journal of the Society of Toxicology 2008;105(1):153-65.
2008: Kembra L Howdeshell; Johnathan Furr; Christy Lambright; Vickie S Wilson; Bryce Ryan; L Earl Gray
Gestational and lactational exposure to ethinyl estradiol, but not bisphenol A, decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male long evans hooded rat.
Toxicological sciences : an official journal of the Society of Toxicology 2008;102(2):371-82.
2008: Rachel L Ruhlen; Kembra L Howdeshell; Jiude Mao; Julia A Taylor; Franklin H Bronson; Retha R Newbold; Wade V Welshons; Frederick S vom Saal
Low phytoestrogen levels in feed increase fetal serum estradiol resulting in the "fetal estrogenization syndrome" and obesity in CD-1 mice.
Environmental health perspectives 2008;116(3):322-8.
2008: Pia Bagamasbad; Kembra L Howdeshell; Laurent M Sachs; Barbara A Demeneix; Robert J Denver
A role for basic transcription element-binding protein 1 (BTEB1) in the autoinduction of thyroid hormone receptor beta.
The Journal of biological chemistry 2008;283(4):2275-85.
2007: Kembra L Howdeshell; Johnathan Furr; Christy Lambright; Cynthia V Rider; Vickie S Wilson; L Earl Gray
Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes.
Toxicological sciences : an official journal of the Society of Toxicology 2007;99(1):190-202.
2007: Chad R Blystone; Christy S Lambright; Kembra L Howdeshell; Johnathan Furr; Robin M Sternberg; Brian C Butterworth; Elizabeth J Durhan; Elizabeth A Makynen; Gerald T Ankley; Vickie S Wilson; Gerald A LeBlanc; L Earl Gray
Sensitivity of fetal rat testicular steroidogenesis to maternal prochloraz exposure and the underlying mechanism of inhibition.
Toxicological sciences : an official journal of the Society of Toxicology 2007;97(2):512-9.
2007: Vickie S Wilson; Kembra L Howdeshell; Christy S Lambright; Johnathan Furr; L Earl Gray
Differential expression of the phthalate syndrome in male Sprague-Dawley and Wistar rats after in utero DEHP exposure.
Toxicology letters 2007;170(3):177-84.
2007: Chad R Blystone; Johnathan Furr; Christy S Lambright; Kembra L Howdeshell; Bryce Ryan; Vickie S Wilson; Gerald A LeBlanc; L Earl Gray
Prochloraz inhibits testosterone production at dosages below those that affect androgen-dependent organ weights or the onset of puberty in the male Sprague Dawley rat.
Toxicological sciences : an official journal of the Society of Toxicology 2007;97(1):65-74.
2006: L Earl Gray; Vickie S Wilson; Tammy E Stoker; Christy Lambright; Johnathan Furr; Nigel Noriega; Kembra L Howdeshell; Gerald T Ankley; Louis Guillette
Adverse effects of environmental antiandrogens and androgens on reproductive development in mammals.
International journal of andrology 2006;29(1):96-104; discussion 105-8.
2005: Barry G Timms; Kembra L Howdeshell; Lesley Barton; Sarahann Bradley; Catherine A Richter; Frederick S vom Saal
Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(19):7014-9.
2003: Kembra L Howdeshell; Paul H Peterman; Barbara M Judy; Julia A Taylor; Carl E Orazio; Rachel L Ruhlen; Frederick S vom Saal; Wade V Welshons
Bisphenol A is released from used polycarbonate animal cages into water at room temperature.
Environmental health perspectives 2003;111(9):1180-7.
2002: L C Alworth; Kembra L Howdeshell; Rachel L Ruhlen; J Kevin Day; Dennis B Lubahn; Hui-Ming (Tim) Huang; Cynthia Besch-Williford; Frederick S vom Saal
Uterine responsiveness to estradiol and DNA methylation are altered by fetal exposure to diethylstilbestrol and methoxychlor in CD-1 mice: effects of low versus high doses.
Toxicology and applied pharmacology 2002;183(1):10-22.
2002: Paola Palanza; Kembra L Howdeshell; Stefano Parmigiani; Frederick S vom Saal
Exposure to a low dose of bisphenol A during fetal life or in adulthood alters maternal behavior in mice.
Environmental health perspectives 2002;110 Suppl 3():415-22.
2002: Kembra L Howdeshell
A model of the development of the brain as a construct of the thyroid system.
Environmental health perspectives 2002;110 Suppl 3():337-48.
2001: Kristina A Thayer; Rachel L Ruhlen; Kembra L Howdeshell; David Lee Buchanan; Paul S Cooke; Diane E Preziosi; Wade V Welshons; J Haseman; Frederick S vom Saal
Altered prostate growth and daily sperm production in male mice exposed prenatally to subclinical doses of 17alpha-ethinyl oestradiol.
Human reproduction (Oxford, England) 2001;16(5):988-96.
1999: Kembra L Howdeshell; Andrew Hotchkiss; Kristina A Thayer; John G Vandenbergh; Frederick S vom Saal
Exposure to bisphenol A advances puberty.
Nature 1999;401(6755):763-4.
1999: R Bigsby; Robert Chapin; George P Daston; B J Davis; J Gorski; L Earl Gray; Kembra L Howdeshell; R T Zoeller; Frederick S vom Saal
Evaluating the effects of endocrine disruptors on endocrine function during development.
Environmental health perspectives 1999;107 Suppl 4():613-8.