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Gareth Howell

Research Profile

Living Beings

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Physiology

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TOP 3
Laura G Reinholdt; Chyuan-Sheng Lin; Danilo G Macalinao; Katharine H Macnicoll; Anne M Czechanski; Leah Rae Donahue; Gareth R Howell; Simon W M John
Generating embryonic stem cells from the inbred mouse strain DBA/2J, a model of glaucoma and other complex diseases.
K Saidas Nair; Mounira Hmani-Aifa; Zain Ali; Alison L Kearney; Danilo G Macalinao; Ioan M Cosma; Walid Bouassida; Bochra Hakim; Zeineb Benzina; Ileana Soto; Peter Söderkvist; Gareth R Howell; Richard S Smith; Hammadi Ayadi; Salma Ben Salem; Simon W M John
Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice.
Gareth R Howell; Richard T Libby; Simon W M John
Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection.

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All Publications

2012: Laura G Reinholdt; Chyuan-Sheng Lin; Danilo G Macalinao; Katharine H Macnicoll; Anne M Czechanski; Leah Rae Donahue; Gareth R Howell; Simon W M John
Generating embryonic stem cells from the inbred mouse strain DBA/2J, a model of glaucoma and other complex diseases.
PloS one 2012;7(11):e50081.
2011: K Saidas Nair; Mounira Hmani-Aifa; Zain Ali; Alison L Kearney; Danilo G Macalinao; Ioan M Cosma; Walid Bouassida; Bochra Hakim; Zeineb Benzina; Ileana Soto; Peter Söderkvist; Gareth R Howell; Richard S Smith; Hammadi Ayadi; Salma Ben Salem; Simon W M John
Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice.
Nature genetics 2011;43(6):579-84.
2008: Gareth R Howell; Richard T Libby; Simon W M John
Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection.
Progress in brain research 2008;173():303-21.
2007: Gareth R Howell; Richard T Libby; Tatjana C Jakobs; Richard S Smith; F Campbell Phalan; Joseph W Barter; Jessica M Barbay; Jeffrey K Marchant; Nagaraju Mahesh; Vittorio porciatti; Alan V Whitmore; Richard H Masland; Simon W M John
Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma.
The Journal of cell biology 2007;179(7):1523-37.
2007: Beth Stevens; Nicola J Allen; Luis E Vazquez; Gareth R Howell; Karen S Christopherson; Navid Nouri; Kristina D Micheva; Adrienne K Mehalow; Andrew D Huberman; Benjamin Stafford; Alexander Sher; Alan Litke; John D Lambris; Stephen J Smith; Simon W M John; Ben A Barres
The classical complement cascade mediates CNS synapse elimination.
Cell 2007;131(6):1164-78.
2007: Gareth R Howell; Mami Shindo; Stephen A Murray; Thomas Gridley; Lawriston A Wilson; John C Schimenti
Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations.
Genetics 2007;175(2):699-707.
2007: Richard T Libby; Gareth R Howell; Iok-Hou Pang; Olga V Savinova; Adrienne K Mehalow; Joseph W Barter; Richard S Smith; Abbot F Clark; Simon W M John
Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model.
BMC neuroscience 2007;8():108.
2007: Gareth R Howell; Richard T Libby; Jeffrey K Marchant; Lawriston A Wilson; Ioan M Cosma; Richard S Smith; Michael G Anderson; Simon W M John
Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1.
BMC genetics 2007;8():45.
2005: Gareth R Howell; Robert J Munroe; John C Schimenti
Transgenic rescue of the mouse t complex haplolethal locus Thl1.
Mammalian genome : official journal of the International Mammalian Genome Society 2005;16(11):838-46.
2005: Lawriston Wilson; Yung-Hao Ching; Michael Farias; Suzanne Hartford; Gareth R Howell; Hongguang Shao; Maja Bucan; John C Schimenti
Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations.
Genome research 2005;15(8):1095-105.
2004: Gareth R Howell; Rebecca A Bergstrom; Robert J Munroe; Jessica Masse; John C Schimenti
Identification of a cryptic lethal mutation in the mouse t(w73) haplotype.
Genetical research 2004;84(3):153-9.