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Steven Howell

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Anatomy

Phenomena

Disorders

Malaria

Procedures

Physiology

Post Translational Protein Processing

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Publications

TOP 3
Bing Xiao; Matthew J Sanders; Elizabeth Underwood; Richard Heath; Faith V Mayer; David Carmena; Chun Jing; Philip A Walker; John F Eccleston; Lesley F Haire; Peter Saiu; Steven A Howell; Rein Aasland; Stephen Martin; David Carling; Steven J Gamblin
Structure of mammalian AMPK and its regulation by ADP.
Solabomi A Ogun; Rita Tewari; Thomas D Otto; Steven A Howell; Ellen Knuepfer; Deirdre A Cunningham; Zhengyao Xu; Arnab Pain; Anthony A Holder
Targeted disruption of py235ebp-1: invasion of erythrocytes by Plasmodium yoelii using an alternative Py235 erythrocyte binding protein.
Qian Wang; Alan Kennedy; Papia Das; Pauline McIntosh; Steven A Howell; Erin R Isaacson; Steven A Hinz; Clare E Davy; John Doorbar
Phosphorylation of the human papillomavirus type 16 E1--E4 protein at T57 by ERK triggers a structural change that enhances keratin binding and protein stability.

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All Publications

2011: Bing Xiao; Matthew J Sanders; Elizabeth Underwood; Richard Heath; Faith V Mayer; David Carmena; Chun Jing; Philip A Walker; John F Eccleston; Lesley F Haire; Peter Saiu; Steven A Howell; Rein Aasland; Stephen Martin; David Carling; Steven J Gamblin
Structure of mammalian AMPK and its regulation by ADP.
Nature 2011;472(7342):230-3.
2011: Solabomi A Ogun; Rita Tewari; Thomas D Otto; Steven A Howell; Ellen Knuepfer; Deirdre A Cunningham; Zhengyao Xu; Arnab Pain; Anthony A Holder
Targeted disruption of py235ebp-1: invasion of erythrocytes by Plasmodium yoelii using an alternative Py235 erythrocyte binding protein.
PLoS pathogens 2011;7(2):e1001288.
2009: Qian Wang; Alan Kennedy; Papia Das; Pauline McIntosh; Steven A Howell; Erin R Isaacson; Steven A Hinz; Clare E Davy; John Doorbar
Phosphorylation of the human papillomavirus type 16 E1--E4 protein at T57 by ERK triggers a structural change that enhances keratin binding and protein stability.
Journal of virology 2009;83(8):3668-83.
2008: Judith L Green; Roxanne R Rees-Channer; Steven A Howell; Stephen Martin; Ellen Knuepfer; Helen M Taylor; Munira Grainger; Anthony A Holder
The motor complex of Plasmodium falciparum: phosphorylation by a calcium-dependent protein kinase.
The Journal of biological chemistry 2008;283(45):30980-9.
2008: Chrislaine Withers-Martinez; Lesley F Haire; Fiona Hackett; Philip A Walker; Steven A Howell; Stephen John Smerdon; Guy G Dodson; Michael J Blackman
Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface.
Journal of molecular biology 2008;375(3):773-81.
2006: Rebecca A O'Donnell; Fiona Hackett; Steven A Howell; Moritz Treeck; Nicole Struck; Zita Krnajski; Chrislaine Withers-Martinez; Tim-Wolf Gilberger; Michael J Blackman
Intramembrane proteolysis mediates shedding of a key adhesin during erythrocyte invasion by the malaria parasite.
The Journal of cell biology 2006;174(7):1023-33.
2006: Solabomi A Ogun; Steven A Howell; Helen M Taylor; Anthony A Holder
A member of the py235 gene family of Plasmodium yoelii encodes an erythrocyte binding protein recognised by a protective monoclonal antibody.
Molecular and biochemical parasitology 2006;147(1):140-3.
2005: Steven A Howell; Fiona Hackett; Artemio M Jongco; Chrislaine Withers-Martinez; Kami Kim; Vernon Bruce Carruthers; Michael J Blackman
Distinct mechanisms govern proteolytic shedding of a key invasion protein in apicomplexan pathogens.
Molecular microbiology 2005;57(5):1342-56.
2004: Xing W Zhou; Michael J Blackman; Steven A Howell; Vernon Bruce Carruthers
Proteomic analysis of cleavage events reveals a dynamic two-step mechanism for proteolysis of a key parasite adhesive complex.
Molecular & cellular proteomics : MCP 2004;3(6):565-76.
2003: Steven A Howell; Isabelle Well; Suzanne L Fleck; Catherine A Kettleborough; Christine R Collins; Michael J Blackman
A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavage.
The Journal of biological chemistry 2003;278(26):23890-8.
2002: Jonathan R Wilson; Chun Jing; Philip A Walker; Stephen Martin; Steven A Howell; G Michael Blackburn; Steven J Gamblin; Bing Xiao
Crystal structure and functional analysis of the histone methyltransferase SET7/9.
Cell 2002;111(1):105-15.
2001: Steven A Howell; Chrislaine Withers-Martinez; Clemens H M Kocken; Alan Thomas; Michael J Blackman
Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1.
The Journal of biological chemistry 2001;276(33):31311-20.
1998: M Brune; Jackie L Hunter; Steven A Howell; Stephen Martin; T L Hazlett; John E T Corrie; Martin R Webb
Mechanism of inorganic phosphate interaction with phosphate binding protein from Escherichia coli.
Biochemistry 1998;37(29):10370-80.