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Peter Howley

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
21
Huibregtse, Jon
17
Scheffner, Martin
9
Phelps, William
8
mcbride, alison
8
Benson, JD
6
Karpova, Alla
6
Lambert, Paul
5
Hanahan, Douglas
5
Goh, Amanda
5
You, Jianxin
5
Schlegel, Richard
5
Walters, Kylie
4
Schweiger, Michal-Ruth
4
Beaudenon, Sylvie
4
Ronco, LV

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Publications

TOP 3
Zheng Gang; Schweiger Michal-Ruth; Martinez-Noel Gustavo; Zheng Leon; Smith Jennifer A; Harper J Wade; Howley Peter M
Brd4 regulation of papillomavirus protein E2 stability.
Vos Robin M; Altreuter Jennifer; White Elizabeth A; Howley Peter M
The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability.
Howley Peter M; Livingston David M
Small DNA tumor viruses: large contributors to biomedical sciences.

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All Publications

2009: Zheng Gang; Schweiger Michal-Ruth; Martinez-Noel Gustavo; Zheng Leon; Smith Jennifer A; Harper J Wade; Howley Peter M
Brd4 regulation of papillomavirus protein E2 stability.
Journal of virology 2009;83(17):8683-92.
2009: Vos Robin M; Altreuter Jennifer; White Elizabeth A; Howley Peter M
The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability.
Journal of virology 2009;83(17):8885-92.
2009: Howley Peter M; Livingston David M
Small DNA tumor viruses: large contributors to biomedical sciences.
Virology 2009;384(2):256-9.
2008: Mulligan Peter; Westbrook Thomas F; Ottinger Matthias; Pavlova Natalya; Chang Bin; Macia Eric; Shi Yu-Jiang; Barretina Jordi; Liu Jinsong; Howley Peter M; Elledge Stephen J; Shi Yang
CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.
Molecular cell 2008;32(5):718-26.
2008: Goh Amanda M; Walters Kylie J; Elsasser Suzanne; Verma Rati; Deshaies Raymond J; Finley Daniel; Howley Peter M
Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins.
BMC biochemistry 2008;9():4.
2007: Schweiger Michal-Ruth; Ottinger Matthias; You Jianxin; Howley Peter M
Brd4-independent transcriptional repression function of the papillomavirus e2 proteins.
Journal of virology 2007;81(18):9612-22.
2007: DeMasi Joseph; Chao Michael C; Kumar Ashu S; Howley Peter M
Bovine papillomavirus E7 oncoprotein inhibits anoikis.
Journal of virology 2007;81(17):9419-25.
2007: Shirakura Masayuki; Murakami Kyoko; Ichimura Tohru; Suzuki Ryosuke; Shimoji Tetsu; Fukuda Kouichirou; Abe Katsutoshi; Sato Shigeko; Fukasawa Masayoshi; Yamakawa Yoshio; Nishijima Masahiro; Moriishi Kohji; Matsuura Yoshiharu; Wakita Takaji; Suzuki Tetsuro; Howley Peter M; Miyamura Tatsuo; Shoji Ikuo
E6AP ubiquitin ligase mediates ubiquitylation and degradation of hepatitis C virus core protein.
Journal of virology 2007;81(3):1174-85.
2006: You Jianxin; Srinivasan Viswanathan; Denis Gerald V; Harrington William J; Ballestas Mary E; Kaye Kenneth M; Howley Peter M
Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes.
Journal of virology 2006;80(18):8909-19.
2006: Schweiger Michal-Ruth; You Jianxin; Howley Peter M
Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function.
Journal of virology 2006;80(9):4276-85.
2006: Nishimura Akiko; Nakahara Tomomi; Ueno Takaharu; Sasaki Kenta; Yoshida Satoshi; Kyo Satoru; Howley Peter M; Sakai Hiroyuki
Requirement of E7 oncoprotein for viability of HeLa cells.
Microbes and infection / Institut Pasteur 2006;8(4):984-93.
2006: Li Lu; Li Zhigang; Howley Peter M; Sacks David B
E6AP and calmodulin reciprocally regulate estrogen receptor stability.
The Journal of biological chemistry 2006;281(4):1978-85.
2006: Howley Peter M
Warts, cancer and ubiquitylation: lessons from the papillomaviruses.
Transactions of the American Clinical and Climatological Association 2006;117():113-26; discussion 126-7.
2005: You Jianxin; Schweiger Michal-Ruth; Howley Peter M
Inhibition of E2 binding to Brd4 enhances viral genome loss and phenotypic reversion of bovine papillomavirus-transformed cells.
Journal of virology 2005;79(23):14956-61.
2005: DeMasi Joseph; Huh Kyung-Won; Nakatani Yoshihiro; Münger Karl; Howley Peter M
Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11486-91.
2005: Huh Kyung-Won; DeMasi Joseph; Ogawa Hidesato; Nakatani Yoshihiro; Howley Peter M; Münger Karl
Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11492-7.
2005: Kirshner Jessica R; Karpova Alla Y; Kops Maren; Howley Peter M
Identification of TRAIL as an interferon regulatory factor 3 transcriptional target.
Journal of virology 2005;79(14):9320-4.
2004: Walters Kylie J; Goh Amanda M; Wang Qinghua; Wagner Gerhard; Howley Peter M
Ubiquitin family proteins and their relationship to the proteasome: a structural perspective.
Biochimica et biophysica acta 2004;1695(1-3):73-87.
2004: Cooper Eric M; Hudson Amy W; Amos Joseph; Wagstaff Joseph; Howley Peter M
Biochemical analysis of Angelman syndrome-associated mutations in the E3 ubiquitin ligase E6-associated protein.
The Journal of biological chemistry 2004;279(39):41208-17.
2004: You Jianxin; Croyle Jennie L; Nishimura Akiko; Ozato Keiko; Howley Peter M
Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes.
Cell 2004;117(3):349-60.
2003: Hudson Amy W; Blom Daniël; Howley Peter M; Ploegh Hidde L
The ER-lumenal domain of the HHV-7 immunoevasin U21 directs class I MHC molecules to lysosomes.
Traffic (Copenhagen, Denmark) 2003;4(12):824-37.
2003: Wang Qinghua; Goh Amanda M; Howley Peter M; Walters Kylie J
Ubiquitin recognition by the DNA repair protein hHR23a.
Biochemistry 2003;42(46):13529-35.
2003: Walters Kylie J; Lech Patrycja J; Goh Amanda M; Wang Qinghua; Howley Peter M
DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12694-9.
2003: Kleijnen Maurits F; Alarcon Rodolfo M; Howley Peter M
The ubiquitin-associated domain of hPLIC-2 interacts with the proteasome.
Molecular biology of the cell 2003;14(9):3868-75.
2003: Wells Susanne I; Aronow Bruce J; Wise Trisha M; Williams Sarah S; Couget Jennifer A; Howley Peter M
Transcriptome signature of irreversible senescence in human papillomavirus-positive cervical cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(12):7093-8.
2002: Münger Karl; Howley Peter M
Human papillomavirus immortalization and transformation functions.
Virus research 2002;89(2):213-28.
2002: Karpova Alla Y; Trost Maren; Murray John M; Cantley Lewis C; Howley Peter M
Interferon regulatory factor-3 is an in vivo target of DNA-PK.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):2818-23.
2002: Walters Kylie J; Kleijnen Maurits F; Goh Amanda M; Wagner Gerhard; Howley Peter M
Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a.
Biochemistry 2002;41(6):1767-77.
2001: Hudson A W; Howley P M; Ploegh H L
A human herpesvirus 7 glycoprotein, U21, diverts major histocompatibility complex class I molecules to lysosomes.
Journal of virology 2001;75(24):12347-58.
2001: Karpova A Y; Ronco L V; Howley P M
Functional characterization of interferon regulatory factor 3a (IRF-3a), an alternative splice isoform of IRF-3.
Molecular and cellular biology 2001;21(13):4169-76.
2000: Karpova A Y; Howley P M; Ronco L V
Dual utilization of an acceptor/donor splice site governs the alternative splicing of the IRF-3 gene.
Genes & development 2000;14(22):2813-8.
2000: Wells S I; Francis D A; Karpova A Y; Dowhanick J J; Benson J D; Howley P M
Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways.
The EMBO journal 2000;19(21):5762-71.
2000: Zhou P; Bogacki R; McReynolds L; Howley P M
Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins.
Molecular cell 2000;6(3):751-6.
2000: Kleijnen M F; Shih A H; Zhou P; Kumar S; Soccio R E; Kedersha N L; Gill G; Howley P M
The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome.
Molecular cell 2000;6(2):409-19.
2000: Kao W H; Beaudenon S L; Talis A L; Huibregtse J M; Howley P M
Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase.
Journal of virology 2000;74(14):6408-17.
2000: Nishimura A; Ono T; Ishimoto A; Dowhanick J J; Frizzell M A; Howley P M; Sakai H
Mechanisms of human papillomavirus E2-mediated repression of viral oncogene expression and cervical cancer cell growth inhibition.
Journal of virology 2000;74(8):3752-60.
2000: Francis D A; Schmid S I; Howley P M
Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells.
Journal of virology 2000;74(6):2679-86.
1999: Harris K F; Shoji I; Cooper E M; Kumar S; Oda H; Howley P M
Ubiquitin-mediated degradation of active Src tyrosine kinase.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13738-43.
1999: Huang L; Kinnucan E; Wang G; Beaudenon S; Howley P M; Huibregtse J M; Pavletich N P
Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.
Science (New York, N.Y.) 1999;286(5443):1321-6.
1999: Oda H; Kumar S; Howley P M
Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9557-62.
1999: Kumar S; Talis A L; Howley P M
Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination.
The Journal of biological chemistry 1999;274(26):18785-92.
1998: Zhou P; Howley P M
Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases.
Molecular cell 1998;2(5):571-80.
1998: Benson J D; Benson M; Howley P M; Struhl K
Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes.
The EMBO journal 1998;17(22):6714-22.
1998: Kasukawa H; Howley P M; Benson J D
A fifteen-amino-acid peptide inhibits human papillomavirus E1-E2 interaction and human papillomavirus DNA replication in vitro.
Journal of virology 1998;72(10):8166-73.
1998: Patrick G N; Zhou P; Kwon Y T; Howley P M; Tsai L H
p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.
The Journal of biological chemistry 1998;273(37):24057-64.
1998: Ronco L V; Karpova A Y; Vidal M; Howley P M
Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity.
Genes & development 1998;12(13):2061-72.
1998: Wathelet M G; Lin C H; Parekh B S; Ronco L V; Howley P M; Maniatis T
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo.
Molecular cell 1998;1(4):507-18.
1998: Talis A L; Huibregtse J M; Howley P M
The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.
The Journal of biological chemistry 1998;273(11):6439-45.
1998: Tong X; Boll W; Kirchhausen T; Howley P M
Interaction of the bovine papillomavirus E6 protein with the clathrin adaptor complex AP-1.
Journal of virology 1998;72(1):476-82.
1997: Tong X; Salgia R; Li J L; Griffin J D; Howley P M
The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase.
The Journal of biological chemistry 1997;272(52):33373-6.
1997: Benson J D; Lawande R; Howley P M
Conserved interaction of the papillomavirus E2 transcriptional activator proteins with human and yeast TFIIB proteins.
Journal of virology 1997;71(10):8041-7.
1997: Yasugi T; Vidal M; Sakai H; Howley P M; Benson J D
Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins.
Journal of virology 1997;71(8):5942-51.
1997: Kumar S; Kao W H; Howley P M
Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity.
The Journal of biological chemistry 1997;272(21):13548-54.
1997: Yamamoto Y; Huibregtse J M; Howley P M
The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing.
Genomics 1997;41(2):263-6.
1997: Tong X; Howley P M
The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4412-7.
1997: Yasugi T; Benson J D; Sakai H; Vidal M; Howley P M
Mapping and characterization of the interaction domains of human papillomavirus type 16 E1 and E2 proteins.
Journal of virology 1997;71(2):891-9.
1997: Maki C G; Howley P M
Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation.
Molecular and cellular biology 1997;17(1):355-63.
1996: Yasugi T; Howley P M
Identification of the structural and functional human homolog of the yeast ubiquitin conjugating enzyme UBC9.
Nucleic acids research 1996;24(11):2005-10.
1996: Maki C G; Huibregtse J M; Howley P M
In vivo ubiquitination and proteasome-mediated degradation of p53(1).
Cancer research 1996;56(11):2649-54.
1996: Khleif S N; DeGregori J; Yee C L; Otterson G A; Kaye F J; Nevins J R; Howley P M
Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4350-4.
1996: Sakai H; Yasugi T; Benson J D; Dowhanick J J; Howley P M
Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions.
Journal of virology 1996;70(3):1602-11.
1995: Dowhanick J J; McBride A A; Howley P M
Suppression of cellular proliferation by the papillomavirus E2 protein.
Journal of virology 1995;69(12):7791-9.
1995: Benson J D; Howley P M
Amino-terminal domains of the bovine papillomavirus type 1 E1 and E2 proteins participate in complex formation.
Journal of virology 1995;69(7):4364-72.
1995: Huibregtse J M; Scheffner M; Beaudenon S; Howley P M
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):5249.
1995: Huibregtse J M; Scheffner M; Beaudenon S; Howley P M
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2563-7.
1995: Vande Pol S B; Howley P M
Negative regulation of the bovine papillomavirus E5, E6, and E7 oncogenes by the viral E1 and E2 genes.
Journal of virology 1995;69(1):395-402.
1994: Scheffner M; Huibregtse J M; Howley P M
Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):8797-801.
1994: Arbeit J M; Münger K; Howley P M; Hanahan D
Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice.
Journal of virology 1994;68(7):4358-68.
1994: Scheffner M; Romanczuk H; Münger K; Huibregtse J M; Mietz J A; Howley P M
Functions of human papillomavirus proteins.
Current topics in microbiology and immunology 1994;186():83-99.
1994: Huibregtse J M; Scheffner M; Howley P M
E6-AP directs the HPV E6-dependent inactivation of p53 and is representative of a family of structurally and functionally related proteins.
Cold Spring Harbor symposia on quantitative biology 1994;59():237-45.
1993: Scheffner M; Huibregtse J M; Vierstra R D; Howley P M
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53.
Cell 1993;75(3):495-505.
1993: Unger T; Mietz J A; Scheffner M; Yee C L; Howley P M
Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation, transdominant inhibition, and transformation suppression.
Molecular and cellular biology 1993;13(9):5186-94.
1993: Huibregtse J M; Scheffner M; Howley P M
Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins.
Molecular and cellular biology 1993;13(8):4918-27.
1993: Arbeit J M; Münger K; Howley P M; Hanahan D
Neuroepithelial carcinomas in mice transgenic with human papillomavirus type 16 E6/E7 ORFs.
The American journal of pathology 1993;142(4):1187-97.
1993: Huibregtse J M; Scheffner M; Howley P M
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.
Molecular and cellular biology 1993;13(2):775-84.
1992: Mietz J A; Unger T; Huibregtse J M; Howley P M
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein.
The EMBO journal 1992;11(13):5013-20.
1992: Del Vecchio A M; Romanczuk H; Howley P M; Baker C C
Transient replication of human papillomavirus DNAs.
Journal of virology 1992;66(10):5949-58.
1992: McBride A A; Klausner R D; Howley P M
Conserved cysteine residue in the DNA-binding domain of the bovine papillomavirus type 1 E2 protein confers redox regulation of the DNA-binding activity in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7531-5.
1992: Scheffner M; Takahashi T; Huibregtse J M; Minna J D; Howley P M
Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins.
Journal of virology 1992;66(8):5100-5.
1992: Scheffner M; Münger K; Huibregtse J M; Howley P M
Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins.
The EMBO journal 1992;11(7):2425-31.
1992: Thierry F; Spyrou G; Yaniv M; Howley P
Two AP1 sites binding JunB are essential for human papillomavirus type 18 transcription in keratinocytes.
Journal of virology 1992;66(6):3740-8.
1992: Chellappan S; Kraus V B; Kroger B; Munger K; Howley P M; Phelps W C; Nevins J R
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4549-53.
1992: Heck D V; Yee C L; Howley P M; Münger K
Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4442-6.
1992: Romanczuk H; Howley P M
Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(7):3159-63.
1992: Phelps W C; Münger K; Yee C L; Barnes J A; Howley P M
Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein.
Journal of virology 1992;66(4):2418-27.
1992: Vande Pol S B; Howley P M
The bovine papillomavirus constitutive enhancer is essential for viral transformation, DNA replication, and the maintenance of latency.
Journal of virology 1992;66(4):2346-58.
1992: Münger K; Scheffner M; Huibregtse J M; Howley P M
Interactions of HPV E6 and E7 oncoproteins with tumour suppressor gene products.
Cancer surveys 1992;12():197-217.
1991: Phelps W C; Bagchi S; Barnes J A; Raychaudhuri P; Kraus V; Münger K; Howley P M; Nevins J R
Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism.
Journal of virology 1991;65(12):6922-30.
1991: Huibregtse J M; Scheffner M; Howley P M
A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18.
The EMBO journal 1991;10(13):4129-35.
1991: McBride A A; Howley P M
Bovine papillomavirus with a mutation in the E2 serine 301 phosphorylation site replicates at a high copy number.
Journal of virology 1991;65(12):6528-34.
1991: McBride A A; Romanczuk H; Howley P M
The papillomavirus E2 regulatory proteins.
The Journal of biological chemistry 1991;266(28):18411-4.
1991: Dostatni N; Lambert P F; Sousa R; Ham J; Howley P M; Yaniv M
The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex.
Genes & development 1991;5(9):1657-71.
1991: Howley P M
Role of the human papillomaviruses in human cancer.
Cancer research 1991;51(18 Suppl):5019s-5022s.
1991: Scheffner M; Münger K; Byrne J C; Howley P M
The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(13):5523-7.
1991: Münger K; Yee C L; Phelps W C; Pietenpol J A; Moses H L; Howley P M
Biochemical and biological differences between E7 oncoproteins of the high- and low-risk human papillomavirus types are determined by amino-terminal sequences.
Journal of virology 1991;65(7):3943-8.
1991: Romanczuk H; Villa L L; Schlegel R; Howley P M
The viral transcriptional regulatory region upstream of the E6 and E7 genes is a major determinant of the differential immortalization activities of human papillomavirus types 16 and 18.
Journal of virology 1991;65(5):2739-44.
1991: Schiffman M H; Bauer H M; Lorincz A T; Manos M M; Byrne J C; Glass A G; Cadell D M; Howley P M
Comparison of Southern blot hybridization and polymerase chain reaction methods for the detection of human papillomavirus DNA.
Journal of clinical microbiology 1991;29(3):573-7.
1991: Spalholz B A; Vande Pol S B; Howley P M
Characterization of the cis elements involved in basal and E2-transactivated expression of the bovine papillomavirus P2443 promoter.
Journal of virology 1991;65(2):743-53.
1991: Thierry F; Howley P M
Functional analysis of E2-mediated repression of the HPV18 P105 promoter.
The New biologist 1991;3(1):90-100.
1991: Howley P M; Münger K; Romanczuk H; Scheffner M; Huibregtse J M
Cellular targets of the oncoproteins encoded by the cancer associated human papillomaviruses.
Princess Takamatsu symposia 1991;22():239-48.
1991: Howley P M; Scheffner M; Huibregtse J; Münger K
Oncoproteins encoded by the cancer-associated human papillomaviruses target the products of the retinoblastoma and p53 tumor suppressor genes.
Cold Spring Harbor symposia on quantitative biology 1991;56():149-55.
1991: Howley P M
Tumor progression in transgenic mice containing the bovine papillomavirus genome.
Basic life sciences 1991;57():103-7; discussion 108-10.
1991: Werness B A; Münger K; Howley P M
Role of the human papillomavirus oncoproteins in transformation and carcinogenic progression.
Important advances in oncology 1991;():3-18.
1990: Scheffner M; Werness B A; Huibregtse J M; Levine A J; Howley P M
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53.
Cell 1990;63(6):1129-36.
1990: Vande Pol S B; Howley P M
A bovine papillomavirus constitutive enhancer is negatively regulated by the E2 repressor through competitive binding for a cellular factor.
Journal of virology 1990;64(11):5420-9.
1990: Romanczuk H; Thierry F; Howley P M
Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters.
Journal of virology 1990;64(6):2849-59.
1990: Werness B A; Levine A J; Howley P M
Association of human papillomavirus types 16 and 18 E6 proteins with p53.
Science (New York, N.Y.) 1990;248(4951):76-9.
1990: Lambert P F; Monk B C; Howley P M
Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants.
Journal of virology 1990;64(2):950-6.
1989: Münger K; Werness B A; Dyson N; Phelps W C; Harlow E; Howley P M
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.
The EMBO journal 1989;8(13):4099-105.
1989: McBride A A; Bolen J B; Howley P M
Phosphorylation sites of the E2 transcriptional regulatory proteins of bovine papillomavirus type 1.
Journal of virology 1989;63(12):5076-85.
1989: Münger K; Phelps W C; Bubb V; Howley P M; Schlegel R
The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes.
Journal of virology 1989;63(10):4417-21.
1989: Lindgren V; Sippola-Thiele M; Skowronski J; Wetzel E; Howley P M; Hanahan D
Specific chromosomal abnormalities characterize fibrosarcomas of bovine papillomavirus type 1 transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(13):5025-9.
1989: Lambert P F; Hubbert N L; Howley P M; Schiller J T
Genetic assignment of multiple E2 gene products in bovine papillomavirus-transformed cells.
Journal of virology 1989;63(7):3151-4.
1989: Sippola-Thiele M; Hanahan D; Howley P M
Cell-heritable stages of tumor progression in transgenic mice harboring the bovine papillomavirus type 1 genome.
Molecular and cellular biology 1989;9(3):925-34.
1989: Lambert P F; Dostatni N; McBride A A; Yaniv M; Howley P M; Arcangioli B
Functional analysis of the papilloma virus E2 trans-activator in Saccharomyces cerevisiae.
Genes & development 1989;3(1):38-48.
1989: McBride A A; Byrne J C; Howley P M
E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(2):510-4.
1989: Hanahan D; Wetzel E; Skowronski J; Sippola-Thiele M; Lindgren V; Howley P
Tumorigenic latency and separable stages during fibrosarcoma development in transgenic mice carrying papillomavirus genomes.
Princess Takamatsu symposia 1989;20():289-96.
1989: Howley P M; Münger K; Werness B A; Phelps W C; Schlegel R
Molecular mechanisms of transformation by the human papillomaviruses.
Princess Takamatsu symposia 1989;20():199-206.
1989: Phelps W C; Yee C L; Münger K; Howley P M
Functional and sequence similarities between HPV16 E7 and adenovirus E1A.
Current topics in microbiology and immunology 1989;144():153-66.
1988: Lambert P F; Howley P M
Bovine papillomavirus type 1 E1 replication-defective mutants are altered in their transcriptional regulation.
Journal of virology 1988;62(11):4009-15.
1988: Hermonat P L; Spalholz B A; Howley P M
The bovine papillomavirus P2443 promoter is E2 trans-responsive: evidence for E2 autoregulation.
The EMBO journal 1988;7(9):2815-22.
1988: Spalholz B A; Byrne J C; Howley P M
Evidence for cooperativity between E2 binding sites in E2 trans-regulation of bovine papillomavirus type 1.
Journal of virology 1988;62(9):3143-50.
1988: Howley P M; Schlegel R
The human papillomaviruses. An overview.
The American journal of medicine 1988;85(2A):155-8.
1988: Phelps W C; Yee C L; Münger K; Howley P M
The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A.
Cell 1988;53(4):539-47.
1988: McBride A A; Schlegel R; Howley P M
The carboxy-terminal domain shared by the bovine papillomavirus E2 transactivator and repressor proteins contains a specific DNA binding activity.
The EMBO journal 1988;7(2):533-9.
1988: Lambert P F; Baker C C; Howley P M
The genetics of bovine papillomavirus type 1.
Annual review of genetics 1988;22():235-58.
1987: Hermonat P L; Howley P M
Mutational analysis of the 3' open reading frames and the splice junction at nucleotide 3225 of bovine papillomavirus type 1.
Journal of virology 1987;61(12):3889-95.
1981: Sarver N; Gruss P; Law M F; Khoury G; Howley P M
Bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector.
Molecular and cellular biology 1981;1(6):486-96.

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