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Gil Atzmon

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Kaori Kato; Clyde B Schechter; Joe Verghese; Richard Zweig; Nir Barzilai; Gil Atzmon
Personality, self-rated health, and cognition in centenarians: do personality and self-rated health relate to cognitive function in advanced age?
Derek M Huffman; John J Lofrese; Gil Atzmon; Leonard H Augenlicht; John P Chamberland; Xueying Zhang; Christos S Mantzoros
Abdominal obesity, independent from caloric intake, accounts for the development of intestinal tumors in Apc(1638N/+) female mice.
Derek M Huffman; Eline P Slagboom; Kenny Ye; Nir Barzilai; Aviv Bergman; Joris Deelen; Gil Atzmon
Distinguishing between longevity and buffered-deleterious genotypes for exceptional human longevity: the case of the MTP gene.

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2013: Kaori Kato; Clyde B Schechter; Joe Verghese; Richard Zweig; Nir Barzilai; Gil Atzmon
Personality, self-rated health, and cognition in centenarians: do personality and self-rated health relate to cognitive function in advanced age?
Aging 2013;5(3):183-91.
2013: Derek M Huffman; John J Lofrese; Gil Atzmon; Leonard H Augenlicht; John P Chamberland; Xueying Zhang; Christos S Mantzoros
Abdominal obesity, independent from caloric intake, accounts for the development of intestinal tumors in Apc(1638N/+) female mice.
Cancer prevention research (Philadelphia, Pa.) 2013;6(3):177-87.
2012: Derek M Huffman; Eline P Slagboom; Kenny Ye; Nir Barzilai; Aviv Bergman; Joris Deelen; Gil Atzmon
Distinguishing between longevity and buffered-deleterious genotypes for exceptional human longevity: the case of the MTP gene.
The journals of gerontology. Series A, Biological sciences and medical sciences 2012;67(11):1153-60.
2012: Danny Ben-Avraham; Radhika Muzumdar; Gil Atzmon
Epigenetic genome-wide association methylation in aging and longevity.
Epigenomics 2012;4(5):503-9.
2012: Christopher L Campbell; David Comas; Maya Dubrovsky; Marc Fellous; Eitan Friedman; Li Hao; Brenna M Henn; Carole Oddoux; Gil Atzmon; Laura R Botigué; Edward Burns; Carlos D Bustamante; Pier F Palamara; Alexander Pearlman; Itsik Pe'er; Harry Ostrer
North African Jewish and non-Jewish populations form distinctive, orthogonal clusters.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(34):13865-70.
2012: Karen N Conneely; Michael R Erdos; Bard J Geesaman; Thomas T Perls; Annibale A Puca; Paola Sebastiani; Nadia Solovieff; Amy J Swift; Gil Atzmon; Clinton T Baldwin; Nir Barzilai; Michael Boehnke; Temuri Budagov; Brian C Capell; Francis S Collins
Human longevity and common variations in the LMNA gene: a meta-analysis.
Aging cell 2012;11(3):475-81.
2012: Kaori Kato; Richard Zweig; Nir Barzilai; Gil Atzmon
Positive attitude towards life and emotional expression as personality phenotypes for centenarians.
Aging 2012;4(5):359-67.
2012: Jennifer Yi-Chun Lai; Michal Melamed; Gil Atzmon; Nir Barzilai; Jill Crandall; Thomas H Hostetter; Markus Bitzer
Family history of exceptional longevity is associated with lower serum uric acid levels in Ashkenazi Jews.
Journal of the American Geriatrics Society 2012;60(4):745-50.
2012: C Velez; J Guevara-Aguirre; T Karafet; P F Palamara; I Pe'er; C Oddoux; Edward R Burns; M Hammer; Gil Atzmon; M Guevara-Aguirre; A Pearlman; L Hao; Harry Ostrer
The impact of Converso Jews on the genomes of modern Latin Americans.
Human genetics 2012;131(2):251-63.
2012: Guiqing Cai; Jonathan L Haines; Adam C Naj; Margaret Pericak-Vance; Mary Sano; Gil Atzmon; Nir Barzilai; Gary Beecham; Joseph Buxbaum
Evidence against a role for rare ADAM10 mutations in sporadic Alzheimer disease.
Neurobiology of aging 2012;33(2):416-417.e3.
2012: Alexandra Mirina; Kenny Ye; Gil Atzmon; Aviv Bergman
Gene size matters.
PloS one 2012;7(11):e49093.
2012: Saurabh Gombar; Jan H J Hoeijmakers; Hwa Jin Jung; Joris Pothof; Gil Atzmon; Nir Barzilai; Brent Calder; Judith Campisi; Feng Dong; Xiao-Li Tian; Jan Vijg; Yousin Suh
Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing.
BMC genomics 2012;13():353.
2012: Eimear E Kenny; Karen Marder; Lloyd Mayer; Dermot P B McGovern; Adele A Mitchell; Jennifer Mulle; Sok Meng Ng; Avi Orr-Urtreger; Harry Ostrer; Laurie Ozelius; Itsik Pe'er; Deborah D Proctor; Ann E Pulver; Jerome I Rotter; Mark S Silverberg; Thomas Ullman; Stephen Warren; Matti Waterman; Wei Zhang; Clara Abraham; Maria Abreu; Gil Atzmon; Nir Barzilai; Aviv Bergman; Steven R Brant; Susan Bressman; Edward R Burns; Judy H Cho; Yehuda Chowers; Lorraine N Clark; Ariel Darvasi; Robert J Desnick; Dana Doheny; Richard H Duerr; Rami Eliakim; Monica Erazo; Nir Giladi; Peter K Gregersen; Hakon Hakonarson; Michelle Jones; Amir Karban; Seymour Katz; Inga Peter
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
PLoS genetics 2012;8(3):e1002559.
2011: Vafa Tabatabaie; Gil Atzmon; Nir Barzilai; Ruth Freeman; swapnil rajpathak; Jill Crandall
Exceptional longevity is associated with decreased reproduction.
Aging 2011;3(12):1202-5.
2011: Stefan Walter; Lei Yu; M Carola Zillikens; Alice Arnold; Gil Atzmon; Stefania Bandinelli; Sebastian E Baumeister; Emelia J Benjamin; David A Bennett; Reiner Biffar; Eric Boerwinkle; Aron S Buchman; David Couper; Philip L De Jager; Ellen W Demerath; Denis A Evans; Luigi Ferrucci; Melissa E Garcia; Vilmundur Gudnason; Tamara B Harris; Wolfgang Hoffmann; Albert Hofman; Robert Kaplan; David Karasik; Douglas P Kiel; Mika Kivimaki; Thomas Kocher; Meena Kumari; Maris Kuningas; Lenore J Launer; Yongmei Liu; Kurt K Lohman; Kathryn L Lunetta; Pamela L Lutsey; Johan Mackenbach; Kristin Marciante; Yuri Milaneschi; Joanne M Murabito; Anne B Newman; Bruce M Psaty; Eric Reiman; Jerome I Rotter; Sudha Seshadri; Michelle D Shardell; Albert V Smith; Toshiko Tanaka; Henning Tiemeier; Gregory J Tranah; Cornelia van Duijn; Uwe Völker; Jeremy Walston; Nora Franceschini
A genome-wide association study of aging.
Neurobiology of aging 2011;32(11):2109.e15-28.
2011: swapnil rajpathak; Saritha Reddy; Gil Atzmon; Orit Ben-David; Jill Crandall; Yingheng Liu; Nir Barzilai
Lifestyle factors of people with exceptional longevity.
Journal of the American Geriatrics Society 2011;59(8):1509-12.
2011: Priya Moorjani; Nick Patterson; Joel N Hirschhorn; Alon Keinan; Li Hao; Gil Atzmon; Edward R Burns; Harry Ostrer; Alkes L Price; David Reich
The history of African gene flow into Southern Europeans, Levantines, and Jews.
PLoS genetics 2011;7(4):e1001373.
2010: Nir Barzilai; Ilan Gabriely; Gil Atzmon; Devorah Rothenberg; Yousin Suh; Aviv Bergman
Genetic studies reveal the role of the endocrine and metabolic systems in aging.
The Journal of clinical endocrinology and metabolism 2010;95(10):4493-500.
2010: Radhika Muzumdar; Derek M Huffman; John W Calvert; Saurabh Jha; Yoni Weinberg; Lingguang Cui; Anjana-Devi Nemkal; Gil Atzmon; Laura E. Klein; Susheel Gundewar; Sang Yong Ji; Madhav Lavu; Benjamin Predmore; David J Lefer
Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(10):1940-8.
2010: Francine Einstein; Derek M Huffman; Sigal Fishman; Elina Jerschow; Hye Heo; Gil Atzmon; Clyde Schechter; Nir Barzilai; Radhika Muzumdar
Aging per se increases the susceptibility to free fatty acid-induced insulin resistance.
The journals of gerontology. Series A, Biological sciences and medical sciences 2010;65(8):800-8.
2010: Reid F Thompson; Gil Atzmon; Ciprian Gheorghe; Hong Qian Liang; Christina Lowes; John M Greally; Nir Barzilai
Tissue-specific dysregulation of DNA methylation in aging.
Aging cell 2010;9(4):506-18.
2010: Gil Atzmon; Li Hao; Itsik Pe'er; Christopher Velez; Alexander Pearlman; Pier Francesco Palamara; Bernice E Morrow; Eitan Friedman; Carole Oddoux; Edward R Burns; Harry Ostrer
Abraham's children in the genome era: major Jewish diaspora populations comprise distinct genetic clusters with shared Middle Eastern Ancestry.
American journal of human genetics 2010;86(6):850-9.
2010: Clyde Schechter; Nir Barzilai; Jill Crandall; Gil Atzmon
Cholesteryl ester transfer protein (CETP) genotype and reduced CETP levels associated with decreased prevalence of hypertension.
Mayo Clinic proceedings. Mayo Clinic 2010;85(6):522-6.
2010: Gil Atzmon; Miook Cho; Richard M Cawthon; Temuri Budagov; Micol Katz; Xiaoman Yang; Glenn Siegel; Aviv Bergman; Derek M Huffman; Clyde Schechter; Woodring E Wright; Jerry W Shay; Nir Barzilai; Diddahally R Govindaraju; Yousin Suh
Evolution in health and medicine Sackler colloquium: Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians.
Proceedings of the National Academy of Sciences of the United States of America 2010;107 Suppl 1():1710-7.
2010: Rosalind J Neuman; Jon Wasson; Gil Atzmon; Julio Wainstein; Yair Yerushalmi; Joseph Cohen; Nir Barzilai; Ilana Blech; Benjamin Glaser; M Alan Permutt
Gene-gene interactions lead to higher risk for development of type 2 diabetes in an Ashkenazi Jewish population.
PloS one 2010;5(3):e9903.
2009: Gil Atzmon; Nir Barzilai; Martin I Surks; Ilan Gabriely
Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity.
The Journal of clinical endocrinology and metabolism 2009;94(12):4768-75.
2009: Ludmila Pawlikowska; Donglei Hu; Scott Huntsman; Andrew Sung; Catherine Chu; Justin Chen; Alexander H Joyner; Nicholas J Schork; Wen-Chi Hsueh; Alexander P Reiner; Bruce M Psaty; Gil Atzmon; Nir Barzilai; Steven R Cummings; Warren S Browner; Pui-Yan Kwok; Elad Ziv
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.
Aging cell 2009;8(4):460-72.
2009: Jeremy Walston; Amy M Matteini; Caroline Nievergelt; Leslie A Lange; Dani M Fallin; Nir Barzilai; Elad Ziv; Ludmila Pawlikowska; Pui Kwok; Steve R Cummings; Charles Kooperberg; Andrea LaCroix; Russell P Tracy; Gil Atzmon; Ethan M Lange; Alex P Reiner
Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults.
Experimental gerontology 2009;44(5):350-5.
2009: Gil Atzmon; Nir Barzilai; Joseph G Hollowell; Martin I Surks; Ilan Gabriely
Extreme longevity is associated with increased serum thyrotropin.
The Journal of clinical endocrinology and metabolism 2009;94(4):1251-4.
2009: Paola Sebastiani; Monty Montano; Annibale Puca; Nadia Solovieff; Toshio Kojima; Meng C Wang; Efthymia Melista; Micah Meltzer; Sylvia E J Fischer; Stacy Andersen; Stephen H Hartley; Amanda Sedgewick; Yasumichi Arai; Aviv Bergman; Nir Barzilai; Dellara F Terry; Alberto Riva; Chiara Viviani Anselmi; Alberto Malovini; Aya Kitamoto; Motoji Sawabe; Tomio Arai; Yasuyuki Gondo; Martin H Steinberg; Nobuyoshi Hirose; Gil Atzmon; Gary Ruvkun; Clinton T Baldwin; Thomas T Perls
RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.
PloS one 2009;4(12):e8210.
2009: Radhika Muzumdar; Derek M Huffman; Gil Atzmon; Christoph Buettner; Laura J Cobb; Sigal Fishman; Temuri Budagov; Lingguang Cui; Francine Einstein; Aruna Poduval; David Hwang; Nir Barzilai; Pinchas Cohen
Humanin: a novel central regulator of peripheral insulin action.
PloS one 2009;4(7):e6334.
2008: Francine Einstein; Sigal Fishman; Jeffery Bauman; Reid Thompson; Derek M Huffman; Gil Atzmon; Nir Barzilai; Radhika Muzumdar
Enhanced activation of a "nutrient-sensing" pathway with age contributes to insulin resistance.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(10):3450-7.
2008: Gil Atzmon; S Blum; Marc Feldman; A Cahaner; Uri Lavi; Jossi Hillel
QTLs detected in a multigenerational resource chicken population.
The Journal of heredity 2008;99(5):528-38.
2008: Radhika Muzumdar; David Allison; Derek M Huffman; Xiaohui Ma; Gil Atzmon; Francine Einstein; Sigal Fishman; Aruna D Poduval; Theresa McVei; Scott W Keith; Nir Barzilai
Visceral adipose tissue modulates mammalian longevity.
Aging cell 2008;7(3):438-40.
2008: Gil Atzmon; Toni I Pollin; Jill Crandall; Keith Tanner; Clyde Schechter; Philipp E Scherer; Marielisa Rincon; Glenn Siegel; Micol Katz; richard lipton; Alan R Shuldiner; Nir Barzilai
Adiponectin levels and genotype: a potential regulator of life span in humans.
The journals of gerontology. Series A, Biological sciences and medical sciences 2008;63(5):447-53.
2008: Yousin Suh; Gil Atzmon; Mi-Ook Cho; David Hwang; Bingrong Liu; Daniel J Leahy; Nir Barzilai; Pinchas Cohen
Functionally significant insulin-like growth factor I receptor mutations in centenarians.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(9):3438-42.
2008: Francine Einstein; Sigal Fishman; Radhika Muzumdar; Xiao Man Yang; Gil Atzmon; Nir Barzilai
Accretion of visceral fat and hepatic insulin resistance in pregnant rats.
American journal of physiology. Endocrinology and metabolism 2008;294(2):E451-5.
2008: Liran Shlush; Gil Atzmon; Roni Weisshof; Doron Behar; Guenady Yudkovsky; Nir Barzilai; Karl Skorecki
Ashkenazi Jewish centenarians do not demonstrate enrichment in mitochondrial haplogroup J.
PloS one 2008;3(10):e3425.
2007: Aviv Bergman; Gil Atzmon; Qian Ye; Thomas MacCarthy; Nir Barzilai
Buffering mechanisms in aging: a systems approach toward uncovering the genetic component of aging.
PLoS computational biology 2007;3(8):e170.
2007: Nahoko Iwata; Jin Zhang; Gil Atzmon; Suzanne Leanza; Jaehyoung Cho; Anne Chomyn; Robert D Burk; Nir Barzilai; Giuseppe Attardi
Aging-related occurrence in Ashkenazi Jews of leukocyte heteroplasmic mtDNA mutation adjacent to replication origin frequently remodeled in Italian centenarians.
Mitochondrion 2007;7(4):267-72.
2007: Gil Atzmon; S Blum; M Feldman; Uri Lavi; Jossi Hillel
Detection of agriculturally important QTLs in chickens and analysis of the factors affecting genotyping strategy.
Cytogenetic and genome research 2007;117(1-4):327-37.
2007: Sigal Fishman; Radhika Muzumdar; Gil Atzmon; Xiaohui Ma; Xiaoman Yang; Francine Einstein; Nir Barzilai
Resistance to leptin action is the major determinant of hepatic triglyceride accumulation in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(1):53-60.
2006: Nir Barzilai; Gil Atzmon; Carol A Derby; J M Bauman; richard lipton
A genotype of exceptional longevity is associated with preservation of cognitive function.
Neurology 2006;67(12):2170-5.
2006: Dellara F Terry; Diego F Wyszynski; Vikki G Nolan; Gil Atzmon; Emily A Schoenhofen; JaeMi Pennington; Stacy L Andersen; Marsha A. Wilcox; Lindsay A Farrer; Nir Barzilai; Clinton T Baldwin; Alexzander Asea
Serum heat shock protein 70 level as a biomarker of exceptional longevity.
Mechanisms of ageing and development 2006;127(11):862-8.
2006: Radhika Muzumdar; Xiaohui Ma; Sigal Fishman; Xiaoman Yang; Gil Atzmon; Patricia Vuguin; Francine Einstein; David Hwang; Pinchas Cohen; Nir Barzilai
Central and opposing effects of IGF-I and IGF-binding protein-3 on systemic insulin action.
Diabetes 2006;55(10):2788-96.
2006: T Lahav; Gil Atzmon; S Blum; Giora Ben-Ari; Steffen Weigend; A Cahaner; Uri Lavi; Jossi Hillel
Marker-assisted selection based on a multi-trait economic index in chicken: Experimental results and simulation.
Animal genetics 2006;37(5):482-8.
2006: Radhika Muzumdar; Xiaohui Ma; Xiaoman Yang; Gil Atzmon; Nir Barzilai
Central resistance to the inhibitory effects of leptin on stimulated insulin secretion with aging.
Neurobiology of aging 2006;27(9):1308-14.
2006: Gil Atzmon; Yefim I Ronin; A Korol; N Yonash; H Cheng; Jossi Hillel
QTLs associated with growth traits and abdominal fat weight and their interactions with gender and hatch in commercial meat-type chickens.
Animal genetics 2006;37(4):352-8.
2006: Gil Atzmon; Marielisa Rincon; Clyde Schechter; Alan R Shuldiner; richard lipton; Aviv Bergman; Nir Barzilai
Lipoprotein genotype and conserved pathway for exceptional longevity in humans.
PLoS biology 2006;4(4):e113.
2005: Dan E Arking; Gil Atzmon; Albert Arking; Nir Barzilai; Harry C Dietz
Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity.
Circulation research 2005;96(4):412-8.
2005: Francine Einstein; Gil Atzmon; Xiao Man Yang; Xiao Hui Ma; Marielisa Rincon; Eric Rudin; Radhika Muzumdar; Nir Barzilai
Differential responses of visceral and subcutaneous fat depots to nutrients.
Diabetes 2005;54(3):672-8.
2005: Gil Atzmon; Marielisa Rincon; Pegah Rabizadeh; Nir Barzilai
Biological evidence for inheritance of exceptional longevity.
Mechanisms of ageing and development 2005;126(2):341-5.
2004: Marielisa Rincon; Radhika Muzumdar; Gil Atzmon; Nir Barzilai
The paradox of the insulin/IGF-1 signaling pathway in longevity.
Mechanisms of ageing and development 2004;125(6):397-403.
2004: Radhika Muzumdar; Xiaohui Ma; Gil Atzmon; Patricia Vuguin; Xiaoman Yang; Nir Barzilai
Decrease in glucose-stimulated insulin secretion with aging is independent of insulin action.
Diabetes 2004;53(2):441-6.
2004: Gil Atzmon; Clyde Schechter; William Greiner; Deborah Davidson; Gad Rennert; Nir Barzilai
Clinical phenotype of families with longevity.
Journal of the American Geriatrics Society 2004;52(2):274-7.
2003: Nir Barzilai; Gil Atzmon; Clyde Schechter; Ernst Schaefer; Adrienne L Cupples; richard lipton; Suzanne Cheng; Alan R Shuldiner
Unique lipoprotein phenotype and genotype associated with exceptional longevity.
JAMA : the journal of the American Medical Association 2003;290(15):2030-40.
2003: Radhika Muzumdar; Xiaohui Ma; Xiaoman Yang; Gil Atzmon; Julia Bernstein; George Karkanias; Nir Barzilai
Physiologic effect of leptin on insulin secretion is mediated mainly through central mechanisms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1130-2.
2002: Gil Atzmon; Xiao Man Yang; Radhika Muzumdar; Xiao Hui Ma; Ilan Gabriely; Nir Barzilai
Differential gene expression between visceral and subcutaneous fat depots.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(11-12):622-8.
2002: Gil Atzmon; Ilan Gabriely; William Greiner; Deborah Davidson; Clyde Schechter; Nir Barzilai
Plasma HDL levels highly correlate with cognitive function in exceptional longevity.
The journals of gerontology. Series A, Biological sciences and medical sciences 2002;57(11):M712-5.
2002: Ilan Gabriely; Xiao Hui Ma; Xiao Man Yang; Gil Atzmon; Michael W Rajala; Anders H Berg; Phillip Scherer; Luciano Rossetti; Nir Barzilai
Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process?
Diabetes 2002;51(10):2951-8.
2002: Gil Atzmon; D Cassuto; Uri Lavi; A Cahaner; G Zeitlin; Jossi Hillel
DNA markers and crossbreeding scheme as means to select sires for heterosis in egg production of chickens.
Animal genetics 2002;33(2):132-9.