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William Hrushesky

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
24
Retsky, Michael
22
Demicheli, Romano
17
Wood, Patricia
11
Gruber, Scott
8
Du-Quiton, Jovelyn
7
Bonadonna, Gianni
7
Valagussa, Pinuccia
6
Matas, Arthur
5
You, Shaojin
3
Peña, Maria Marjorette
3
Sothern, Robert
3
Lincoln, David
3
Gukas, Isaac
3
Berger, Franklin
3
Bjarnason, Georg

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Publications

TOP 3
Oh Eun-Young; Wood Patricia A; Yang Xiaoming; Hrushesky William J M
Discovery of candidate genes and pathways that may help explain fertility cycle stage dependent post-resection breast cancer outcome.
Yang Xiaoming; Wood Patricia A; Ansell Christine M; Quiton Dinah Faith T; Oh Eun-Yeong; Du-Quiton Jovelyn; Hrushesky William J M
The circadian clock gene Per1 suppresses cancer cell proliferation and tumor growth at specific times of day.
Yang Xiaoming; Wood Patricia A; Oh Eun-Young; Du-Quiton Jovelyn; Ansell Christine M; Hrushesky William J M
Down regulation of circadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm.

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All Publications

2009: Oh Eun-Young; Wood Patricia A; Yang Xiaoming; Hrushesky William J M
Discovery of candidate genes and pathways that may help explain fertility cycle stage dependent post-resection breast cancer outcome.
Breast cancer research and treatment 2009;118(2):345-59.
2009: Yang Xiaoming; Wood Patricia A; Ansell Christine M; Quiton Dinah Faith T; Oh Eun-Yeong; Du-Quiton Jovelyn; Hrushesky William J M
The circadian clock gene Per1 suppresses cancer cell proliferation and tumor growth at specific times of day.
Chronobiology international 2009;26(7):1323-39.
2009: Yang Xiaoming; Wood Patricia A; Oh Eun-Young; Du-Quiton Jovelyn; Ansell Christine M; Hrushesky William J M
Down regulation of circadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm.
Breast cancer research and treatment 2009;117(2):423-31.
2009: Chung Hyewon; Lee Hyunju; Lamoke Folami; Hrushesky William J M; Wood Patricia A; Jahng Wan Jin
Neuroprotective role of erythropoietin by antiapoptosis in the retina.
Journal of neuroscience research 2009;87(10):2365-74.
2009: Yang Xiaoming; Wood Patricia A; Ansell Christine M; Ohmori Masami; Oh Eun-Yeong; Xiong Yin; Berger Franklin G; Peña Maria Marjorette O; Hrushesky William J M
Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.
Journal of biochemistry 2009;145(3):289-97.
2009: Singletary Jamil; Wood Patricia A; Du-Quiton Jovelyn; Wang Song; Yang Xiaoming; Vishnoi Shobhit; Hrushesky William J M
Imaging multidimensional therapeutically relevant circadian relationships.
International journal of biomedical imaging 2009;2009():231539.
2009: Retsky Michael W; Hrushesky William J M; Gukas Isaac D
Hypothesis: primary antiangiogenic method proposed to treat early stage breast cancer.
BMC cancer 2009;9():7.
2008: Wood Patricia A; Yang Xiaoming; Taber Andrew; Oh Eun-Young; Ansell Christine; Ayers Stacy E; Al-Assaad Ziad; Carnevale Kevin; Berger Franklin G; Peña Maria Marjorette O; Hrushesky William J M
Period 2 mutation accelerates ApcMin/+ tumorigenesis.
Molecular cancer research : MCR 2008;6(11):1786-93.
2008: Demicheli R; Retsky M W; Hrushesky W J M; Baum M; Gukas I D
The effects of surgery on tumor growth: a century of investigations.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(11):1821-8.
2008: Oh Eun-Young; Wood Patricia A; Du-Quiton Jovelyn; Hrushesky William J M
Seasonal modulation of post-resection breast cancer metastasis.
Breast cancer research and treatment 2008;111(2):219-28.
2008: Retsky M W; Demicheli R; Hrushesky W J M; Baum M; Gukas I D
Dormancy and surgery-driven escape from dormancy help explain some clinical features of breast cancer.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2008;116(7-8):730-41.
2008: Ramanathan Ramesh K; Bjarnason Georg A; Bernard Stephen Alan; Desimone Philip; Braich Theodore; Evars Joseph P; Hrushesky William J; Jolivet Jacques
A four-arm, randomized, multicenter phase II trial of oxaliplatin combined with varying schedules of 5-fluorouracil as first-line therapy in previously untreated advanced colorectal cancer.
Clinical colorectal cancer 2008;7(2):134-9.
2007: Demicheli Romano; Retsky Michael W; Hrushesky William J M; Baum Michael
Tumor dormancy and surgery-driven interruption of dormancy in breast cancer: learning from failures.
Nature clinical practice. Oncology 2007;4(12):699-710.
2007: Demicheli Romano; Retsky Michael W; Hrushesky William J M; Baum Michael; Gukas Isaac D; Jatoi Ismail
Racial disparities in breast cancer outcome: insights into host-tumor interactions.
Cancer 2007;110(9):1880-8.
2007: Retsky Michael W; Demicheli Romano; Gukas Isaac D; Hrushesky William J M
Enhanced surgery-induced angiogenesis among premenopausal women might partially explain excess breast cancer mortality of blacks compared to whites: an hypothesis.
International journal of surgery (London, England) 2007;5(5):300-4.
2007: Hrushesky William J M; Retsky Michael; Baum Michael; Demicheli Romano
Re: Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer.
Journal of the National Cancer Institute 2007;99(13):1053; author reply 1053-4.
2007: Berk Lawrence; Berkey Brian; Rich Tyvin; Hrushesky William; Blask David; Gallagher Michael; Kudrimoti Mahesh; McGarry Ronald C; Suh John; Mehta Minesh
Randomized phase II trial of high-dose melatonin and radiation therapy for RPA class 2 patients with brain metastases (RTOG 0119).
International journal of radiation oncology, biology, physics 2007;68(3):852-7.
2007: Demicheli Romano; Hrushesky William J M; Retsky Michael W; Bonadonna Gianni; Valagussa Pinuccia
Comment to "Effect of primary tumor extirpation in breast cancer patients who present with stage IV disease and intact primary tumor" by G V Babiera, R Rao, L Feng, F Meric-Bernstam, H M Kuerer, S E Singletary, K K Hunt, M I Ross, K M Gwyn, B W Feig, F C Ames, G N Horthobagyi. Ann Surg Oncol 2006;13:776-782.
Annals of surgical oncology 2007;14(4):1519-20.
2006: Demicheli Romano; Biganzoli Elia; Boracchi Patrizia; Greco Marco; Hrushesky William J M; Retsky Michael W
Allometric scaling law questions the traditional mechanical model for axillary lymph node involvement in breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(27):4391-6.
2006: Wood Patricia A; Du-Quiton Jovelyn; You Shaojin; Hrushesky William J M
Circadian clock coordinates cancer cell cycle progression, thymidylate synthase, and 5-fluorouracil therapeutic index.
Molecular cancer therapeutics 2006;5(8):2023-33.
2006: Kanabrocki E L; Hermida R C; Haseman M B; Bettis K; Young R M I; Mathew J P; Potkul R; Hrushesky W J M
Chronotherapy of ovarian cancer: effect on blood variables and serum cytokines. A case report.
La Clinica terapeutica 2006;157(4):349-54.
2006: Demicheli Romano; Bonadonna Gianni; Greco Marco; Hrushesky William J M; Moliterni Angela; Retsky Michael W; Valagussa Pinuccia; Zambetti Milvia
Comment to Anderson WF, Jatoi I, Devesa SS: distinct breast cancer incidence and prognostic patterns in the NCI'S SEER program: suggesting a possible link between etiology and outcome. Breast Cancer Res Treat 90:127-137, 2005.
Breast cancer research and treatment 2006;97(3):341-3.
2006: You Shaojin; Ohmori Masami; Peña Maria Marjorette O; Nassri Basel; Quiton Jovelyn; Al-Assad Ziad A; Liu Lucy; Wood Patricia A; Berger Sondra H; Liu Zhijian; Wyatt Michael D; Price Robert L; Berger Franklin G; Hrushesky William J M
Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice.
International journal of experimental pathology 2006;87(3):227-36.
2006: Retsky Michael W; Demicheli Romano; Hrushesky William J M
Screening and breast cancer.
The New England journal of medicine 2006;354(7):767-9; author reply 767-9.
2006: Retsky Michael W; Hrushesky William; Baum Michael
Sociodemographic determinants of cancer treatment health literacy.
Cancer 2006;106(3):726-7; author reply 727.
2006: Hrushesky William J M; Sothern Robert B; Rietveld Wop J; Du-Quiton Jovelyn; Boon Mathilde E
Sun exposure, sexual behavior and uterine cervical human papilloma virus.
International journal of biometeorology 2006;50(3):167-73.
2006: Halberg Franz; Cornélissen Germaine; Ulmer Waldemar; Blank Mikhail; Hrushesky William; Wood Patricia; Singh Rajesh K; Wang Zhengrong
Cancer chronomics III. Chronomics for cancer, aging, melatonin and experimental therapeutics researchers.
Journal of experimental therapeutics & oncology 2006;6(1):73-84.
2005: Levin R D; Daehler M A; Grutsch J F; Quiton J; Lis C G; Peterson C; Gupta D; Watson K; Layer D; Huff-Adams S; Desai B; Sharma P; Wallam M; Delioukina M; Ball P; Bryant M; Ashford M; Copeland D; Ohmori M; Wood P A; Hrushesky W J M
Circadian function in patients with advanced non-small-cell lung cancer.
British journal of cancer 2005;93(11):1202-8.
2005: Demicheli Romano; Bonadonna Gianni; Valagussa Pinuccia; Retsky Michael W; Hrushesky William J M; Baum Michael
Comment to Jatoi et al. report.
Breast cancer research and treatment 2005;93(1):1-2.
2005: Demicheli R; Miceli R; Moliterni A; Zambetti M; Hrushesky W J M; Retsky M W; Valagussa P; Bonadonna G
Breast cancer recurrence dynamics following adjuvant CMF is consistent with tumor dormancy and mastectomy-driven acceleration of the metastatic process.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(9):1449-57.
2005: Hrushesky William J M; Sothern Robert B; Rietveld Wop J; Du Quiton Jovelyn; Boon Mathilde E
Season, sun, sex, and cervical cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(8):1940-7.
2005: Wood Patricia A; Bove Kathleen; You Shaojin; Chambers Ann; Hrushesky William J M
Cancer growth and spread are saltatory and phase-locked to the reproductive cycle through mediators of angiogenesis.
Molecular cancer therapeutics 2005;4(7):1065-75.
2005: Wood Patricia A; Hrushesky William J M
Sex cycle modulates cancer growth.
Breast cancer research and treatment 2005;91(1):95-102.
2005: You Shaojin; Wood Patricia A; Xiong Yin; Kobayashi Minoru; Du-Quiton Jovelyn; Hrushesky William J M
Daily coordination of cancer growth and circadian clock gene expression.
Breast cancer research and treatment 2005;91(1):47-60.
2005: Baum Michael; Demicheli Romano; Hrushesky William; Retsky Michael
Does surgery unfavourably perturb the "natural history" of early breast cancer by accelerating the appearance of distant metastases?
European journal of cancer (Oxford, England : 1990) 2005;41(4):508-15.
2005: Dominitz Jason A; Boyko Edward J; Koepsell Thomas D; Heagerty Patrick J; Maynard Charles; Sporleder Jennifer L; Stenhouse Andrew; Kling Mitchel A; Hrushesky William; Zeilman Charles; Sontag Stephen; Shah Nikunj; Ona Fernando; Anand Bhupinder; Subik Marc; Imperiale Thomas F; Nakhle Samer; Ho Sam B; Bini Edmund J; Lockhart Bruce; Ahmad Jawad; Sasaki Anna; van der Linden Brian; Toro Doris; Martinez-Souss Jaime; Huilgol Vivek; Eisen Seth; Young Keith A
Elevated prevalence of hepatitis C infection in users of United States veterans medical centers.
Hepatology (Baltimore, Md.) 2005;41(1):88-96.
2005: Retsky Michael; Demicheli Romano; Hrushesky William J M
Authors respond to controversy surrounding breast cancer study.
International journal of surgery (London, England) 2005;3(4):235-9.
2005: Retsky Michael; Demicheli Romano; Hrushesky William J M
Does surgery induce angiogenesis in breast cancer? Indirect evidence from relapse pattern and mammography paradox.
International journal of surgery (London, England) 2005;3(3):179-87.
2005: Retsky Michael; Demicheli Romano; Hrushesky William; Speer John; Swartzendruber Douglas; Wardwell Robert
Recent translational research: computational studies of breast cancer.
Breast cancer research : BCR 2005;7(1):37-40.
2004: Hrushesky William; Wood Patricia; Levi Francis; von Roemeling Reinhard; Bjarnason Georg; Focan Christian; Meier Klaus; Cornélissen Germaine; Halberg Franz
A recent illustration of some essentials of circadian chronotherapy study design.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(14):2971-2; author reply 2972.
2004: You Shaojin; Li Wei; Kobayashi Minoru; Xiong Yin; Hrushesky William; Wood Patricia
Creation of a stable mammary tumor cell line that maintains fertility-cycle tumor biology of the parent tumor.
In vitro cellular & developmental biology. Animal 2004;40(7):187-95.
2004: Hrushesky William J M; Blask David E
Re: Melatonin and breast cancer: a prospective study.
Journal of the National Cancer Institute 2004;96(11):888-9.
2004: Demicheli Romano; Bonadonna Gianni; Hrushesky William J M; Retsky Michael W; Valagussa Pinuccia
Menopausal status dependence of early mortality reduction due to diagnosis of smaller breast cancers (T1 v T2-T3): relevance to screening.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(1):102-7.
2004: Demicheli Romano; Bonadonna Gianni; Hrushesky William J M; Retsky Michael W; Valagussa Pinuccia
Menopausal status dependence of the timing of breast cancer recurrence after surgical removal of the primary tumour.
Breast cancer research : BCR 2004;6(6):R689-96.
2004: Retsky Michael; Bonadonna Gianni; Demicheli Romano; Folkman Judah; Hrushesky William; Valagussa Pinuccia
Hypothesis: Induced angiogenesis after surgery in premenopausal node-positive breast cancer patients is a major underlying reason why adjuvant chemotherapy works particularly well for those patients.
Breast cancer research : BCR 2004;6(4):R372-4.
2003: Lis Christopher G; Grutsch James F; Wood Patricia; You Mark; Rich Ivan; Hrushesky William J M
Circadian timing in cancer treatment: the biological foundation for an integrative approach.
Integrative cancer therapies 2003;2(2):105-11.
2003: Retsky Michael; Demicheli Romano; Hrushesky William
Breast cancer screening: controversies and future directions.
Current opinion in obstetrics & gynecology 2003;15(1):1-8.
2002: Hrushesky William J M
Androgen suppression and irradiation for locally advanced prostate cancer.
Lancet 2002;360(9349):1987; author reply 1987-8.
2002: Hrushesky William J M
Re: Mastectomy and oophorectomy by menstrual cycle phase in women with operable breast cancer.
Journal of the National Cancer Institute 2002;94(22):1720-1.
2002: Bove Kathleen; Lincoln David W; Wood Patricia A; Hrushesky William J M
Fertility cycle influence on surgical breast cancer cure.
Breast cancer research and treatment 2002;75(1):65-72.
2002: Kobayashi Minoru; Wood Patricia A; Hrushesky William J M
Circadian chemotherapy for gynecological and genitourinary cancers.
Chronobiology international 2002;19(1):237-51.
2001: Retsky M; Demicheli R; Hrushesky W
Breast cancer screening for women aged 40-49 years: screening may not be the benign process usually thought.
Journal of the National Cancer Institute 2001;93(20):1572.
2001: Hrushesky W J
Tumor chronobiology.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):27-30.
2001: Bjarnason G A; Jordan R C; Wood P A; Li Q; Lincoln D W; Sothern R B; Hrushesky W J; Ben-David Y
Circadian expression of clock genes in human oral mucosa and skin: association with specific cell-cycle phases.
The American journal of pathology 2001;158(5):1793-801.
2001: Retsky M; Demicheli R; Hrushesky W
Wounding from biopsy and breast-cancer progression.
Lancet 2001;357(9261):1048.
2001: Mizumura Y; Matsumura Y; Hamaguchi T; Nishiyama N; Kataoka K; Kawaguchi T; Hrushesky W J; Moriyasu F; Kakizoe T
Cisplatin-incorporated polymeric micelles eliminate nephrotoxicity, while maintaining antitumor activity.
Japanese journal of cancer research : Gann 2001;92(3):328-36.
2001: Retsky M; Demicheli R; Hrushesky W
Premenopausal status accelerates relapse in node positive breast cancer: hypothesis links angiogenesis, screening controversy.
Breast cancer research and treatment 2001;65(3):217-24.
2000: Hrushesky W J
The temporal organization of life: the impact of multi-frequency non-linear biologic time structure upon the host-cancer balance.
Japanese journal of clinical oncology 2000;30(12):529-33.
2000: Lincoln D W; Hrushesky W J; Wood P A
Circadian organization of thymidylate synthase activity in normal tissues: a possible basis for 5-fluorouracil chronotherapeutic advantage.
International journal of cancer. Journal international du cancer 2000;88(3):479-85.
2000: Hrushesky W J
Rhythmic menstrual cycle modulation of breast cancer biology.
Journal of surgical oncology 2000;74(3):238-41.
2000: Thrall M M; Wood P; King V; Rivera W; Hrushesky W
Investigation of the comparative toxicity of 5-FU bolus versus 5-FU continuous infusion circadian chemotherapy with concurrent radiation therapy in locally advanced rectal cancer.
International journal of radiation oncology, biology, physics 2000;46(4):873-81.
1999: Hrushesky W J; Lester B; Lannin D
Circadian coordination of cancer growth and metastatic spread.
International journal of cancer. Journal international du cancer 1999;83(3):365-73.
1999: Hrushesky W J; Vyzula R; Wood P A
Fertility maintenance and 5-fluorouracil timing within the mammalian fertility cycle.
Reproductive toxicology (Elmsford, N.Y.) 1999;13(5):413-20.
1998: Hrushesky W J; Lannin D; Haus E
Evidence for an ontogenetic basis for circadian coordination of cancer cell proliferation.
Journal of the National Cancer Institute 1998;90(19):1480-4.
1998: Wood P A; Hrushesky W J; Klevecz R
Distinct circadian time structures characterize myeloid and erythroid progenitor and multipotential cell clonogenicity as well as marrow precursor proliferation dynamics.
Experimental hematology 1998;26(6):523-33.
1998: Hagen A A; Hrushesky W J
Menstrual timing of breast cancer surgery.
American journal of surgery 1998;175(3):245-61.
1997: Hrushesky W J; Wood P A
Circadian time structure of septic shock: timing is everything.
The Journal of infectious diseases 1997;175(5):1283-4.
1996: Tzannis S T; Hrushesky W J; Wood P A; Przybycien T M
Irreversible inactivation of interleukin 2 in a pump-based delivery environment.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5460-5.
1996: Wood P A; Hrushesky W J
Circadian rhythms and cancer chemotherapy.
Critical reviews in eukaryotic gene expression 1996;6(4):299-343.
1996: Hrushesky W J
Menstrual cycle timing of breast cancer resection.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1996;140():27-40.
1995: Wood P A; Hrushesky W J
Erythropoietin usage in patients with cancer.
The cancer journal from Scientific American 1995;1(4):243-6.
1995: Hrushesky W J
Square pegs in round holes.
International journal of cancer. Journal international du cancer 1995;62(5):651-2.
1995: Wong M K; Bjarnason G A; Hrushesky W J; Webster P; Morava-Protzner I; Towers M
Steroid-responsive interstitial lung disease in patients receiving 2'-deoxy-5-fluorouridine-infusion chemotherapy. A report of three cases.
Cancer 1995;75(10):2558-64.
1995: Wood P A; Hrushesky W J
Cisplatin-associated anemia: an erythropoietin deficiency syndrome.
The Journal of clinical investigation 1995;95(4):1650-9.
1995: Hrushesky W J
Menstrual cycle timing of breast cancer resection: prospective study is overdue.
Journal of the National Cancer Institute 1995;87(2):143-4.
1995: Wood P A; Hrushesky W J
Biological perspectives on circadian cancer therapy.
The Journal of infusional chemotherapy 1995;5(4):182-90.
1995: Hrushesky W J
Cancer chronotherapy: is there a right time in the day to treat?
The Journal of infusional chemotherapy 1995;5(1):38-43.
1995: Hrushesky W J
Larry Scheving and cancer chronotherapy.
The Journal of infusional chemotherapy 1995;5(1):1-2.
1994: Hrushesky W J
The Department of Veterans Affairs' unique clinical cancer research effort.
Cancer 1994;74(9 Suppl):2701-9.
1994: Hrushesky W J
Mammography and the menstrual cycle.
International journal of cancer. Journal international du cancer 1994;59(1):151.
1994: Hrushesky W J; Langevin T; Kim Y J; Wood P A
Circadian dynamics of tumor necrosis factor alpha (cachectin) lethality.
The Journal of experimental medicine 1994;180(3):1059-65.
1993: Hrushesky W J
Circadian pharmacodynamics of anticancer therapies.
Clinical chemistry 1993;39(11 Pt 2):2413-8.
1993: Hrushesky W J; Bjarnason G A
Circadian cancer therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993;11(7):1403-17.
1993: Hrushesky W J
Breast cancer and the menstrual cycle.
Journal of surgical oncology 1993;53(1):1-3.
1993: Hrushesky W J
Circadian cancer pharmacodynamics.
Annali dell'Istituto superiore di sanità 1993;29(4):705-10.
1992: Bluming A Z; Hrushesky W J
Optimal timing of initial breast cancer surgery.
Annals of internal medicine 1992;116(3):268.
1992: Gruber S A; Erdmann G R; Burke B A; Moss A; Bowers L; Hrushesky W J; Cipolle R J; Canafax D M; Matas A J
Mizoribine pharmacokinetics and pharmacodynamics in a canine renal allograft model of local immunosuppression.
Transplantation 1992;53(1):12-9.
1991: Buchi K N; Moore J G; Hrushesky W J; Sothern R B; Rubin N H
Circadian rhythm of cellular proliferation in the human rectal mucosa.
Gastroenterology 1991;101(2):410-5.
1991: Hrushesky W J; Fader D J; Berestka J S; Sommer M; Hayes J; Cope F O
Diminishment of respiratory sinus arrhythmia foreshadows doxorubicin-induced cardiomyopathy.
Circulation 1991;84(2):697-707.
1991: Hrushesky W J
Reprogramming SynchroMed pumps: unanticipated inaccuracy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1991;9(6):1089-90.
1991: Hrushesky W J
Quantitative respiratory sinus arrhythmia analysis. A simple noninvasive, reimbursable measure of cardiac wellness and dysfunction.
Annals of the New York Academy of Sciences 1991;618():67-101.
1991: Bluming A; Hrushesky W J
The effect of surgical timing within the fertility cycle on breast cancer outcome.
Annals of the New York Academy of Sciences 1991;618():277-91.
1991: Hrushesky W J
Temporally optimizable delivery systems--sine qua non for molecular medicine. Preface.
Annals of the New York Academy of Sciences 1991;618():xi-xvii.
1991: Hrushesky W J
The multifrequency (circadian, fertility cycle, and season) balance between host and cancer.
Annals of the New York Academy of Sciences 1991;618():228-56.
1990: Hrushesky W J; von Roemeling R; Lanning R M; Rabatin J T
Circadian-shaped infusions of floxuridine for progressive metastatic renal cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1990;8(9):1504-13.
1990: Hrushesky W J
Health care for US veterans and others.
Lancet 1990;336(8708):182.
1990: Hrushesky W J; Bluming A Z; Gruber S A
Menstrual influence on surgical cure of breast cancer.
Lancet 1990;335(8695):984.
1990: Hrushesky W J
More evidence for circadian rhythm effects in cancer chemotherapy: the fluoropyrimidine story.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1990;2(3):65-8.
1990: von Roemeling R; Hrushesky W J
Determination of the therapeutic index of floxuridine by its circadian infusion pattern.
Journal of the National Cancer Institute 1990;82(5):386-93.
1990: Gruber S A; Cipolle R J; Tzardis P; Skjei K L; Jossart G; Abed J F; Canafax D M; Burke B A; Matas A J; Hrushesky W J
Pharmacodynamics of local heparin infusion in a canine renal allograft model.
The Journal of pharmacology and experimental therapeutics 1990;252(2):733-8.
1990: Gruber S A; Canafax D M; Cipolle R J; Erdmann G R; Burke B A; Matas A J; Simmons R L; Hrushesky W J
Local immunosuppression of the vascularized graft.
Surgery 1990;107(2):209-14.
1990: Lanning R M; von Roemeling R; Hrushesky W J
Circadian-based infusional FUDR therapy.
Oncology nursing forum 1990;17(1):49-56.
1990: Sothern R B; Rhame F; Suarez C; Fletcher C; Sackett-Lundeen L; Haus E; Hrushesky W J
Oral temperature rhythmometry and substantial within-day variation in zidovudine levels following steady-state dosing in human immunodeficiency virus (HIV) infection.
Progress in clinical and biological research 1990;341A():67-76.
1990: Swoyer J; Rhame F; Hrushesky W; Sackett-Lundeen L; Sothern R; Gale H; Haus E
Circadian rhythm alteration in HIV infected subjects.
Progress in clinical and biological research 1990;341A():437-49.
1990: Schraufek S R; Sothern R B; Voegele M; Ainsworth B; Serfass R; Leon A; Khanuja H S; Hrushesky W J
Enhancement of respiratory sinus arrhythmia by moderate exercise.
Progress in clinical and biological research 1990;341A():283-96.
1990: Lanning R M; Hrushesky W J
Outpatient time-specified infusion of fluoropyrimidines by implanted pump is less costly than flat delivery by external pump.
Progress in clinical and biological research 1990;341B():397-409.
1990: Hrushesky W J
Cancer chronotherapy: a drug delivery challenge.
Progress in clinical and biological research 1990;341A():1-10.
1989: Gruber S A; Hrushesky W J; Cipolle R J; Erdmann G R; Burke B A; Skjei K L; Mueller R P; Fryd D S; Matas A J; Simmons R L
Local immunosuppression with reduced systemic toxicity in a canine renal allograft model.
Transplantation 1989;48(6):936-43.
1989: Gruber S A; Hrushesky W J; Canafax D M; Cipolle R J; Burke B A; Matas A J; Ascher N L; Simmons R L
Local prednisolone infusion of canine renal allografts.
Transplantation 1989;48(6):1072-5.
1989: von Roemeling R; Hrushesky W J
Circadian patterning of continuous floxuridine infusion reduces toxicity and allows higher dose intensity in patients with widespread cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(11):1710-9.
1989: Hrushesky W J; Bluming A Z; Gruber S A; Sothern R B
Menstrual influence on surgical cure of breast cancer.
Lancet 1989;2(8669):949-52.
1989: Gruber S A; Nichol K L; Sothern R B; Malone M E; Potter J D; Lakatua D; Hrushesky W J
Menstrual history and breast cancer surgery.
Breast cancer research and treatment 1989;13(3):278.
1989: Gruber S A; Burke B A; Canafax D M; Hrushesky W J; Cipolle R J; Erdmann G R; Matas A; Simmons R L; Najarian J S
Feasibility of vascular catheter placement for intrarenal infusion in a canine autotransplant model.
Transplantation proceedings 1989;21(1 Pt 1):1125-6.
1989: Sothern R B; Lévi F; Haus E; Halberg F; Hrushesky W J
Control of a murine plasmacytoma with doxorubicin-cisplatin: dependence on circadian stage of treatment.
Journal of the National Cancer Institute 1989;81(2):135-45.
1988: Mormont M C; von Roemeling R; Sothern R B; Berestka J S; Langevin T R; Wick M; Hrushesky W J
Circadian rhythm and seasonal dependence in the toxicological response of mice to epirubicin.
Investigational new drugs 1988;6(4):273-83.
1988: Hrushesky W J; Gruber S A; Sothern R B; Hoffman R A; Lakatua D; Carlson A; Cerra F; Simmons R L
Natural killer cell activity: age, estrous- and circadian-stage dependence and inverse correlation with metastatic potential.
Journal of the National Cancer Institute 1988;80(15):1232-7.
1988: Gruber S A; Hoffman R A; Sothern R B; Lakatua D; Carlson A; Simmons R L; Hrushesky W J
Splenocyte natural killer cell activity and metastatic potential are inversely dependent on estrous stage.
Surgery 1988;104(2):398-403.
1988: Ratajczak H V; Sothern R B; Hrushesky W J
Estrous influence on surgical cure of a mouse breast cancer.
The Journal of experimental medicine 1988;168(1):73-83.
1988: Canafax D M; Cipolle R J; Hrushesky W J; Rabatin J T; Min D I; Graves N M; Sutherland D E; Bowers L D
The chronopharmacokinetics of cyclosporine and its metabolites in recipients of pancreas allografts.
Transplantation proceedings 1988;20(2 Suppl 2):471-7.
1988: von Roemeling R; Rabatin J T; Fraley E E; Hrushesky W J
Progressive metastatic renal cell carcinoma controlled by continuous 5-fluoro-2-deoxyuridine infusion.
The Journal of urology 1988;139(2):259-62.
1988: Kanabrocki E L; Snedeker P W; Zieher S J; Raymond R; Gordey J; Bird T; Sothern R B; Hrushesky W J; Marks G; Olwin J H
Circadian characteristics of dialyzable and non-dialyzable human urinary electrolytes, trace elements and total solids.
Chronobiology international 1988;5(2):175-84.
1988: Cipolle R J; Canafax D M; Rabatin J; Bowers L D; Sutherland D E; Hrushesky W J
Time-dependent disposition of cyclosporine after pancreas transplantation, and application of chronopharmacokinetics to improve immunosuppression.
Pharmacotherapy 1988;8(1):47-51.
1988: Scheving L E; Tsai T H; Sothern R B; Hrushesky W J
Circadian susceptibility-resistance cycles to radiation and their manipulability by methylene blue.
Pharmacology & therapeutics 1988;39(1-3):397-402.
1988: Hrushesky W J; Berestka J S; von Roemeling R; Olshefski R; Langevin T R; Potish R A; Delaney J P; Ellefson M; Schwartz S
Methylene blue protects intestinal mucosa from free radical-mediated sublethal radiation damage.
Free radical biology & medicine 1988;5(4):207-13.
1988: Hrushesky W J; Von Roemeling R; Fraley E E; Rabatin J T
Circadian-based infusional chrono-chemotherapy controls progressive metastatic renal cell carcinoma.
Seminars in surgical oncology 1988;4(2):110-5.
1987: Hrushesky W J; Nygaard S D; Young J
Timing may be a critical factor in drug therapy.
Cancer treatment reports 1987;71(12):1321.
1987: Hrushesky W J
The rationale for non-zero-order drug delivery using automatic, computer-based drug delivery systems (chronotherapy).
Journal of biological response modifiers 1987;6(6):587-98.
1987: Hrushesky W J; Roemeling R V; Wood P A; Langevin T R; Lange P; Fraley E
High-dose intensity, circadian-timed doxorubicin and cisplatin adjuvant chemotherapy for bladder cancer.
Cancer treatment reports 1987;71(10):915-9.
1987: Hrushesky W J; Roemeling R V; Wood P A; Langevin T R; Lange P; Farley E
High-dose intensity systemic therapy of metastatic bladder cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1987;5(3):450-5.
1987: Focan C; Collette J; Levi F; Touitou Y; Hrushesky W; Franchimont P
[Biological rhythms and tumor markers in man. With special reference to the carcinoembryonic antigen (CEA) and alpha fetoprotein (AFP) in digestive system tumors]
Acta gastro-enterologica Belgica 1987;50(1):12-21.
1987: Roemeling R V; Hrushesky W J
Circadian pattern of continuous FUDR infusion reduces toxicities.
Progress in clinical and biological research 1987;227B():357-73.
1986: Hrushesky W J; von Roemeling R
Chemotherapy-induced vomiting: circadian drug timing as a source of predictable within-patient variability.
Cancer treatment reports 1986;70(11):1347-8.
1986: Focan C; Focan-Henrard D; Collette J; Mechkouri M; Levi F; Hrushesky W; Touitou Y; Franchimont P
Cancer-associated alteration of circadian rhythms in carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) in humans.
Anticancer research 1986;6(5):1137-44.
1986: von Roemeling R; MacDonald M; Langevin T; Buchwald H; Hrushesky W J
Chemotherapy via implanted infusion pump: new perspectives for delivery of long-term continuous treatment.
Oncology nursing forum 1986;13(2):17-24.
1986: Roemeling R V; Olshefski R; Langevin T; Berestka J; Reusch J J; Reusch J E; Lakatua D; Wick M R; Hrushesky W J
Cisplatin chronotherapy and disulfiram rescue reduce toxicity without interfering with anticancer activity: animal findings and preliminary clinical experiences.
Chronobiology international 1986;3(1):55-64.
1986: Roemeling R V; Hrushesky W J
Advanced transitional cell bladder cancer: a treatable disease.
Seminars in surgical oncology 1986;2(2):76-89.
1985: Hrushesky W J
Utility of non-invasive instantaneous screening test for drug-induced cardiac damage.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1985;3(10):1438-9.
1985: Roemeling R V; Christiansen N P; Hrushesky W J
Lack of antiemetic effect of high-dose metoclopramide.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1985;3(9):1273-6.
1985: Hrushesky W J
Distinguishing between renal allograft rejection and cyclosporin nephrotoxicity.
Lancet 1985;2(8453):501.
1985: Hrushesky W J
Cyclosporine timing and kidney damage.
The New England journal of medicine 1985;313(3):184.
1985: Trugman J; Hogenkamp H P; Roelofs R; Hrushesky W J
Cisplatin neurotoxicity: failure to demonstrate vitamin B12 inactivation.
Cancer treatment reports 1985;69(4):453-5.
1985: Hrushesky W J
Circadian timing of cancer chemotherapy.
Science (New York, N.Y.) 1985;228(4695):73-5.
1985: Hrushesky W J; Olshefski R; Wood P; Meshnick S; Eaton J W
Modifying intracellular redox balance: an approach to improving therapeutic index.
Lancet 1985;1(8428):565-7.
1985: Magnus G; Cavallini M; Halberg F; Cornelissen G; Sutherland D E; Najarian J A; Hrushesky W J
Circadian toxicology of cyclosporin.
Toxicology and applied pharmacology 1985;77(1):181-5.
1985: Rosenberg C A; Hrushesky W J; Langevin T; Kennedy B J
Hormonal and chemotherapeutic treatment of prostatic carcinoma; Dunning adenocarcinoma of the prostate in Copenhagen-Fischer rats.
Oncology 1985;42(1):48-54.
1984: Hrushesky W J; Vukelich M; Steiner B; Dell I; Mukai K
24-hour mean pulse. Simple predictor of doxorubicin-induced cardiac damage.
The American journal of medicine 1984;77(3):399-406.
1984: Roelofs R I; Hrushesky W; Rogin J; Rosenberg L
Peripheral sensory neuropathy and cisplatin chemotherapy.
Neurology 1984;34(7):934-8.
1984: Hrushesky W J; Fader D; Schmitt O; Gilbertsen V
The respiratory sinus arrhythmia: a measure of cardiac age.
Science (New York, N.Y.) 1984;224(4652):1001-4.
1984: Hrushesky W J; Shimp W; Kennedy B J
Lack of age-dependent cisplatin nephrotoxicity.
The American journal of medicine 1984;76(4):579-84.
1984: Hrushesky W J; Vukelich M
Circadian mesor of recumbent pulse--cost-effective predictor of doxorubicin-induced congestive heart failure.
Chronobiology international 1984;1(1):59-66.
1983: Hrushesky W J
The clinical application of chronobiology to oncology.
The American journal of anatomy 1983;168(4):519-42.
1983: Hrushesky W J; Merdink J; Abdel-Monem M M
Circadian rhythmicity of polyamine urinary excretion.
Cancer research 1983;43(8):3944-7.
1982: Levi F; Hrushesky W J; Borch R F; Pleasants M E; Kennedy B J; Halberg F
Cisplatin urinary pharmacokinetics and nephrotoxicity: a common circadian mechanism.
Cancer treatment reports 1982;66(11):1933-8.
1982: Hrushesky W J; Borch R; Levi F
Circadian time dependence of cisplatin urinary kinetics.
Clinical pharmacology and therapeutics 1982;32(3):330-9.
1982: Levi F A; Hrushesky W J; Halberg F; Langevin T R; Haus E; Kennedy B J
Lethal nephrotoxicity and hematologic toxicity of cis-diamminedichloroplatinum ameliorated by optimal circadian timing and hydration.
European journal of cancer & clinical oncology 1982;18(5):471-7.
1982: Levi F A; Hrushesky W J; Blomquist C H; Lakatua D J; Haus E; Halberg F; Kennedy B J
Reduction of cis-diamminedichloroplatinum nephrotoxicity in rats by optimal circadian drug timing.
Cancer research 1982;42(3):950-5.
1982: Hrushesky W J; Levi F A; Halberg F; Kennedy B J
Circadian stage dependence of cis-diamminedichloroplatinum lethal toxicity in rats.
Cancer research 1982;42(3):945-9.
1980: Levi F; Halberg F; Haus E; Sanchez de la Peña S; Sothern R B; Halberg E; Hrushesky W; Brown H; Scheving L E; Kennedy B J
Synthetic adrenocorticotropin for optimizing murine circadian chronotolerance for adriamycin.
Chronobiologia 1980;7(2):227-44.
1979: Gordon L I; Hrushesky W; Oken M M; Kay N E; Rydell R E
Chronic lymphocytic leukemia in association with a second lymphoproliferative disorder: response to chemotherapy in two cases.
Medical and pediatric oncology 1979;7(2):111-6.
1977: Hrushesky W
Thrombocytopenia induced by low-dose subcutaneous heparin.
Lancet 1977;2(8051):1286.
1977: Hrushesky W J; Murphy G P
Current status of the therapy of advanced renal carcinoma.
Journal of surgical oncology 1977;9(3):277-88.
1976: Hrushesky W
L-asparaginase activity in acute nonlymphocytic leukemia.
Cancer treatment reports 1976;60(7):966-7.
1976: Hrushesky W J
Serpentine supravenous 5-fluorouracil (NSC-19893) hyperpigmentation.
Cancer treatment reports 1976;60(5):639.
1976: Hrushesky W J; Slavik M; Penta J; Muggia F
The "other" asparaginase.
Medical and pediatric oncology 1976;2(4):441-2.
1974: Hrushesky W J; Murphy G P
Evaluation of chemotherapeutic agents in a new murine renal carcinoma model.
Journal of the National Cancer Institute 1974;52(4):1117-22.
1973: Hrushesky W J; Murphy G P
Investigation of a new renal tumor model.
The Journal of surgical research 1973;15(5):327-36.
1973: Murphy G P; Hrushesky W J
A murine renal cell carcinoma.
Journal of the National Cancer Institute 1973;50(4):1013-25.

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