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Gin Hsieh

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Penile Erection

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TOP 3
Chandran Prasant; Pai Madhavi; Blomme Eric A; Hsieh Gin C; Decker Michael W; Honore Prisca
Pharmacological modulation of movement-evoked pain in a rat model of osteoarthritis.
Zhu C Z; Mikusa J P; Fan Y; Hollingsworth P R; Pai M; Chandran P; Daza A V; Yao B B; Dart M J; Meyer M D; Decker M W; Hsieh G C; Honore P
Peripheral and central sites of action for the non-selective cannabinoid agonist WIN 55,212-2 in a rat model of post-operative pain.
Perez-Medrano Arturo; Donnelly-Roberts Diana L; Honore Prisca; Hsieh Gin C; Namovic Marian T; Peddi Sridhar; Shuai Qi; Wang Ying; Faltynek Connie R; Jarvis Michael F; Carroll William A
Discovery and biological evaluation of novel cyanoguanidine P2X(7) antagonists with analgesic activity in a rat model of neuropathic pain.

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2009: Chandran Prasant; Pai Madhavi; Blomme Eric A; Hsieh Gin C; Decker Michael W; Honore Prisca
Pharmacological modulation of movement-evoked pain in a rat model of osteoarthritis.
European journal of pharmacology 2009;613(1-3):39-45.
2009: Zhu C Z; Mikusa J P; Fan Y; Hollingsworth P R; Pai M; Chandran P; Daza A V; Yao B B; Dart M J; Meyer M D; Decker M W; Hsieh G C; Honore P
Peripheral and central sites of action for the non-selective cannabinoid agonist WIN 55,212-2 in a rat model of post-operative pain.
British journal of pharmacology 2009;157(4):645-55.
2009: Perez-Medrano Arturo; Donnelly-Roberts Diana L; Honore Prisca; Hsieh Gin C; Namovic Marian T; Peddi Sridhar; Shuai Qi; Wang Ying; Faltynek Connie R; Jarvis Michael F; Carroll William A
Discovery and biological evaluation of novel cyanoguanidine P2X(7) antagonists with analgesic activity in a rat model of neuropathic pain.
Journal of medicinal chemistry 2009;52(10):3366-76.
2009: Strakhova Marina I; Nikkel Arthur L; Manelli Arlene M; Hsieh Gin C; Esbenshade Timothy A; Brioni Jorge D; Bitner Robert S
Localization of histamine H4 receptors in the central nervous system of human and rat.
Brain research 2009;1250():41-8.
2008: Liu Huaqing; Altenbach Robert J; Carr Tracy L; Chandran Prasant; Hsieh Gin C; Lewis La Geisha R; Manelli Arlene M; Milicic Ivan; Marsh Kennan C; Miller Thomas R; Strakhova Marina I; Vortherms Timothy A; Wakefield Brian D; Wetter Jill M; Witte David G; Honore Prisca; Esbenshade Timothy A; Brioni Jorge D; Cowart Marlon D
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Journal of medicinal chemistry 2008;51(22):7094-8.
2008: Cowart Marlon D; Altenbach Robert J; Liu Huaqing; Hsieh Gin C; Drizin Irene; Milicic Ivan; Miller Thomas R; Witte David G; Wishart Neil; Fix-Stenzel Shannon R; McPherson Michael J; Adair Ronald M; Wetter Jill M; Bettencourt Brian M; Marsh Kennan C; Sullivan James P; Honore Prisca; Esbenshade Timothy A; Brioni Jorge D
Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class of histamine H4 receptor antagonists with improved druglikeness and in vivo efficacy in pain and inflammation models.
Journal of medicinal chemistry 2008;51(20):6547-57.
2008: Altenbach Robert J; Adair Ronald M; Bettencourt Brian M; Black Lawrence A; Fix-Stenzel Shannon R; Gopalakrishnan Sujatha M; Hsieh Gin C; Liu Huaqing; Marsh Kennan C; McPherson Michael J; Milicic Ivan; Miller Thomas R; Vortherms Timothy A; Warrior Usha; Wetter Jill M; Wishart Neil; Witte David G; Honore Prisca; Esbenshade Timothy A; Hancock Arthur A; Brioni Jorge D; Cowart Marlon D
Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligands.
Journal of medicinal chemistry 2008;51(20):6571-80.
2008: Frost Jennifer M; Dart Michael J; Tietje Karin R; Garrison Tiffany R; Grayson George K; Daza Anthony V; El-Kouhen Odile F; Miller Loan N; Li Lanlan; Yao Betty B; Hsieh Gin C; Pai Madhavi; Zhu Chang Z; Chandran Prasant; Meyer Michael D
Indol-3-yl-tetramethylcyclopropyl ketones: effects of indole ring substitution on CB2 cannabinoid receptor activity.
Journal of medicinal chemistry 2008;51(6):1904-12.
2008: Yao B B; Hsieh G C; Frost J M; Fan Y; Garrison T R; Daza A V; Grayson G K; Zhu C Z; Pai M; Chandran P; Salyers A K; Wensink E J; Honore P; Sullivan J P; Dart M J; Meyer M D
In vitro and in vivo characterization of A-796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models.
British journal of pharmacology 2008;153(2):390-401.
2008: Chin C-L; Tovcimak A E; Hradil V P; Seifert T R; Hollingsworth P R; Chandran P; Zhu C Z; Gauvin D; Pai M; Wetter J; Hsieh G C; Honore P; Frost J M; Dart M J; Meyer M D; Yao B B; Cox B F; Fox G B
Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI.
British journal of pharmacology 2008;153(2):367-79.
2007: Chen Yung-Wu; Smith Morey L; Sheets Michael; Ballaron Steve; Trevillyan James M; Burke Sandra E; Rosenberg Teresa; Henry Cindy; Wagner Rolf; Bauch Joy; Marsh Kennan; Fey Thomas A; Hsieh Gin; Gauvin Donna; Mollison Karl W; Carter George W; Djuric Stevan W
Zotarolimus, a novel sirolimus analogue with potent anti-proliferative activity on coronary smooth muscle cells and reduced potential for systemic immunosuppression.
Journal of cardiovascular pharmacology 2007;49(4):228-35.
2006: Patel Meena V; Kolasa Teodozyj; Mortell Kathleen; Matulenko Mark A; Hakeem Ahmed A; Rohde Jeffrey J; Nelson Sherry L; Cowart Marlon D; Nakane Masaki; Miller Loan N; Uchic Marie E; Terranova Marc A; El-Kouhen Odile F; Donnelly-Roberts Diana L; Namovic Marian T; Hollingsworth Peter R; Chang Renjie; Martino Brenda R; Wetter Jill M; Marsh Kennan C; Martin Ruth; Darbyshire John F; Gintant Gary; Hsieh Gin C; Moreland Robert B; Sullivan James P; Brioni Jorge D; Stewart Andrew O
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction.
Journal of medicinal chemistry 2006;49(25):7450-65.
2006: Honore Prisca; Donnelly-Roberts Diana; Namovic Marian T; Hsieh Gin; Zhu Chang Z; Mikusa Joe P; Hernandez Gricelda; Zhong Chengmin; Gauvin Donna M; Chandran Prasant; Harris Richard; Medrano Arturo Perez; Carroll William; Marsh Kennan; Sullivan James P; Faltynek Connie R; Jarvis Michael F
A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat.
The Journal of pharmacology and experimental therapeutics 2006;319(3):1376-85.
2006: Kolasa Teodozyj; Matulenko Mark A; Hakeem Ahmed A; Patel Meena V; Mortell Kathleen; Bhatia Pramila; Henry Rodger; Nakane Masaki; Hsieh Gin C; Terranova Marc A; Uchic Marie E; Miller Loan N; Chang Renje; Donnelly-Roberts Diana L; Namovic Marian T; Hollingsworth Peter R; Martino Brenda; El Kouhen Odile; Marsh Kennan C; Wetter Jill M; Moreland Robert B; Brioni Jorge D; Stewart Andrew O
1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction.
Journal of medicinal chemistry 2006;49(17):5093-109.
2005: Wagner Rolf; Mollison Karl W; Liu Luping; Henry Cynthia L; Rosenberg Teresa A; Bamaung Nwe; Tu Noah; Wiedeman Paul E; Or Yatsun; Luly Jay R; Lane Benjamin C; Trevillyan James; Chen Yung-Wu; Fey Thomas; Hsieh Gin; Marsh Kennan; Nuss Merrill; Jacobson Peer B; Wilcox Denise; Carlson Richard P; Carter George W; Djuric Stevan W
Rapamycin analogs with reduced systemic exposure.
Bioorganic & medicinal chemistry letters 2005;15(23):5340-3.
2005: Moreland Robert B; Patel Meena; Hsieh Gin C; Wetter Jill M; Marsh Kennan; Brioni Jorge D
A-412997 is a selective dopamine D4 receptor agonist in rats.
Pharmacology, biochemistry, and behavior 2005;82(1):140-7.
2005: Martino Brenda; Hsieh Gin C; Hollingsworth Peter R; Mikusa Joseph P; Moreland Robert B; Bitner R Scott
Central oxytocinergic and dopaminergic mechanisms regulating penile erection in conscious rats.
Pharmacology, biochemistry, and behavior 2005;81(4):797-804.
2005: Nakane Masaki; Cowart Marlon D; Hsieh Gin C; Miller Loan; Uchic Marie E; Chang Renjie; Terranova Marc A; Donnelly-Roberts Diana L; Namovic Marian T; Miller Thomas R; Wetter Jill M; Marsh Kennan; Stewart Andrew O; Brioni Jorge D; Moreland Robert B
2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist.
Neuropharmacology 2005;49(1):112-21.
2005: Basso Ana M; Gallagher Kelly B; Bratcher Natalie A; Brioni Jorge D; Moreland Robert B; Hsieh Gin C; Drescher Karla; Fox Gerard B; Decker Michael W; Rueter Lynne E
Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(7):1257-68.
2005: Zhu Chang Z; Hsieh Gin; Ei-Kouhen Odile; Wilson Sonya G; Mikusa Joe P; Hollingsworth Peter R; Chang Renjie; Moreland Robert B; Brioni Jorge; Decker Michael W; Honore Prisca
Role of central and peripheral mGluR5 receptors in post-operative pain in rats.
Pain 2005;114(1-2):195-202.
2004: Polakowski James S; Segreti Jason A; Cox Bryan F; Hsieh Gin C; Kolasa Teodozyj; Moreland Robert B; Brioni Jorge D
Effects of selective dopamine receptor subtype agonists on cardiac contractility and regional haemodynamics in rats.
Clinical and experimental pharmacology & physiology 2004;31(12):837-41.
2004: Cowart Marlon; Latshaw Steven P; Bhatia Pramila; Daanen Jerome F; Rohde Jeffrey; Nelson Sherry L; Patel Meena; Kolasa Teodozyi; Nakane Masaki; Uchic Marie E; Miller Loan N; Terranova Marc A; Chang Renjie; Donnelly-Roberts Diana L; Namovic Marian T; Hollingsworth Peter R; Martino Brenda R; Lynch James J; Sullivan James P; Hsieh Gin C; Moreland Robert B; Brioni Jorge D; Stewart Andrew O
Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction.
Journal of medicinal chemistry 2004;47(15):3853-64.
2004: Brioni Jorge D; Moreland Robert B; Cowart Marlon; Hsieh Gin C; Stewart Andrew O; Hedlund Petter; Donnelly-Roberts Diana L; Nakane Masaki; Lynch James J; Kolasa Teodozyi; Polakowski James S; Osinski Mark A; Marsh Kennan; Andersson Karl-Erik; Sullivan James P
Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(17):6758-63.
2004: Hsieh Gin C; Hollingsworth Peter R; Martino Brenda; Chang Renjie; Terranova Marc A; O'Neill Alyssa B; Lynch James J; Moreland Robert B; Donnelly-Roberts Diana L; Kolasa Teodozyi; Mikusa Joseph P; McVey Jill M; Marsh Kennan C; Sullivan James P; Brioni Jorge D
Central mechanisms regulating penile erection in conscious rats: the dopaminergic systems related to the proerectile effect of apomorphine.
The Journal of pharmacology and experimental therapeutics 2004;308(1):330-8.
2003: Hsieh Gin C; O'Neill Alyssa B; Moreland Robert B; Sullivan James P; Brioni Jorge D
YC-1 potentiates the nitric oxide/cyclic GMP pathway in corpus cavernosum and facilitates penile erection in rats.
European journal of pharmacology 2003;458(1-2):183-9.
2003: Miller Loan N; Nakane Masaki; Hsieh Gin C; Chang Renjie; Kolasa Teodozyi; Moreland Robert B; Brioni Jorge D
A-350619: a novel activator of soluble guanylyl cyclase.
Life sciences 2003;72(9):1015-25.
2002: Nakane M; Hsieh G; Miller L N; Chang R; Terranova M A; Moreland R B; Kolasa T; Brioni J D
Activation of soluble guanylate cyclase causes relaxation of corpus cavernosum tissue: synergism of nitric oxide and YC-1.
International journal of impotence research 2002;14(2):121-7.
2002: Brioni J D; Nakane M; Hsieh G C; Moreland R B; Kolasa T; Sullivan J P
Activators of soluble guanylate cyclase for the treatment of male erectile dysfunction.
International journal of impotence research 2002;14(1):8-14.
2001: Hsieh G C; Kolasa T; Sullivan J P; Brioni J D
Dual mechanism of action of nicorandil on rabbit corpus cavernosal smooth muscle tone.
International journal of impotence research 2001;13(4):240-6.
2001: Moreland R B; Hsieh G; Nakane M; Brioni J D
The biochemical and neurologic basis for the treatment of male erectile dysfunction.
The Journal of pharmacology and experimental therapeutics 2001;296(2):225-34.
2000: Djuric S W; BaMaung N Y; Basha A; Liu H; Luly J R; Madar D J; Sciotti R J; Tu N P; Wagenaar F L; Wiedeman P E; Zhou X; Ballaron S; Bauch J; Chen Y W; Chiou X G; Fey T; Gauvin D; Gubbins E; Hsieh G C; Marsh K C; Mollison K W; Pong M; Shaughnessy T K; Sheets M P; Smith M; Trevillyan J M; Warrior U; Wegner C D; Carter G W
3,5-Bis(trifluoromethyl)pyrazoles: a novel class of NFAT transcription factor regulator.
Journal of medicinal chemistry 2000;43(16):2975-81.
1999: Burke S E; Lubbers N L; Chen Y W; Hsieh G C; Mollison K W; Luly J R; Wegner C D
Neointimal formation after balloon-induced vascular injury in Yucatan minipigs is reduced by oral rapamycin.
Journal of cardiovascular pharmacology 1999;33(6):829-35.
1999: Mollison K W; Fey T A; Gauvin D M; Kolano R M; Sheets M P; Smith M L; Pong M; Nikolaidis N M; Lane B C; Trevillyan J M; Cannon J; Marsh K; Carter G W; Or Y S; Chen Y W; Hsieh G C; Luly J R
A macrolactam inhibitor of T helper type 1 and T helper type 2 cytokine biosynthesis for topical treatment of inflammatory skin diseases.
The Journal of investigative dermatology 1999;112(5):729-38.
1999: Chen Y W; Smith M L; Sheets M P; Ballaron S J; Trevillyan J M; Fey T A; Gauvin D M; Kolano R; Pong M S; Hsieh G C; Bauch J; Marsh K; Carter G; Luly J; Djuric S; Mollison K W
Ex vivo assessment of immunosuppression in undiluted whole blood from pigs dosed with tacrolimus (FK506).
Clinical immunology (Orlando, Fla.) 1999;90(1):133-40.
1998: Wang A X; Xie Q; Lane B; Mollison K W; Hsieh G C; Marsh K; Sheets M P; Luly J R; Coghlan M J
Synthesis and immunosuppressant activity of pyrazole carboxamides.
Bioorganic & medicinal chemistry letters 1998;8(19):2787-92.
1998: Wagner R; Rhoades T A; Or Y S; Lane B C; Hsieh G; Mollison K W; Luly J R
32-Ascomycinyloxyacetic acid derived immunosuppressants. Independence of immunophilin binding and immunosuppressive potency.
Journal of medicinal chemistry 1998;41(11):1764-76.
1998: Kawai M; Gunawardana I W; Mollison K W; Hsieh G C; Lane B C; Luly J R
Studies on an immunosuppressive macrolactam, ascomycin: synthesis of a C-33 hydroxyl derivative.
Bioorganic & medicinal chemistry letters 1998;8(8):935-8.
1998: Fey T A; Krause R A; Hsieh G C; Andrews J M; Bretheim P T; Morgan S J; Luly J R; Mollison K W
Improved methods for transplanting split-heart neonatal cardiac grafts into the ear pinna of mice and rats.
Journal of pharmacological and toxicological methods 1998;39(1):9-17.
1998: Mollison K W; Fey T A; Krause R A; Andrews J M; Bretheim P T; Cusick P K; Hsieh G C; Luly J R
Nephrotoxicity studies of the immunosuppressants tacrolimus (FK506) and ascomycin in rat models.
Toxicology 1998;125(2-3):169-81.
1997: Mollison K W; Fey T A; Krause R A; Andrews J M; Bretheim P T; Brandt J A; Kawai M; Wagner R; Hsieh G C; Luly J R
Discovery of less nephrotoxic FK506 analogs and determining immunophilin dependence of immunosuppressant nephrotoxicity with a novel single-dose rat cisplatin potentiation assay.
The Journal of pharmacology and experimental therapeutics 1997;283(3):1509-19.
1996: Mollison K W; Andrews J M; Fey T A; Miller L N; Krause R A; Bretheim P T; Brandt J A; Wagner R; Lane B C; Hsieh G C; Luly J R
Discovery of FK 506 analogues that are nontoxic to mouse pancreatic beta cells in vitro but show diabetogenic potential when administered to the rat.
Transplantation proceedings 1996;28(6):3185-8.
1993: Kawai M; Lane B C; Hsieh G C; Mollison K W; Carter G W; Luly J R
Structure-activity profiles of macrolactam immunosuppressant FK-506 analogues.
FEBS letters 1993;316(2):107-13.

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Gin Hsieh

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