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Ya-Ling Hsu

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Po-Lin Kuo; Szi-Hui Liao; Ming-Shyan Huang; Jen-Yu Hung; Ya-Ling Hsu
MicroRNA-33a functions as a bone metastasis suppressor in lung cancer by targeting parathyroid hormone related protein.
Ming-Ju Tsai; Kwou-Yeung Wu; Rei-Cheng Yang; Hsin-Su Yu; Yi-Jen Chen; Ya-Ling Hsu; Po-Lin Kuo
Heat effect induces production of inflammatory cytokines through heat shock protein 90 pathway in cornea cells.
Jen-Yu Hung; Chung-Yi Chen; Ya-Ling Hsu; Ming-Shyan Huang; En-Shyh Lin; Ching-Wen Wen; Po-Lin Kuo
Subamolide a induces mitotic catastrophe accompanied by apoptosis in human lung cancer cells.

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2013: Po-Lin Kuo; Szi-Hui Liao; Ming-Shyan Huang; Jen-Yu Hung; Ya-Ling Hsu
MicroRNA-33a functions as a bone metastasis suppressor in lung cancer by targeting parathyroid hormone related protein.
Biochimica et biophysica acta 2013;1830(6):3756-66.
2013: Ming-Ju Tsai; Kwou-Yeung Wu; Rei-Cheng Yang; Hsin-Su Yu; Yi-Jen Chen; Ya-Ling Hsu; Po-Lin Kuo
Heat effect induces production of inflammatory cytokines through heat shock protein 90 pathway in cornea cells.
Current eye research 2013;38(4):464-71.
2013: Jen-Yu Hung; Chung-Yi Chen; Ya-Ling Hsu; Ming-Shyan Huang; En-Shyh Lin; Ching-Wen Wen; Po-Lin Kuo
Subamolide a induces mitotic catastrophe accompanied by apoptosis in human lung cancer cells.
Evidence-based complementary and alternative medicine : eCAM 2013;2013():828143.
2012: Po-Lin Kuo; Kun-Hung Shen; Shun-Hsing Hung; Ya-Ling Hsu
CXCL1/GROα increases cell migration and invasion of prostate cancer by decreasing fibulin-1 expression through NF-κB/HDAC1 epigenetic regulation.
Carcinogenesis 2012;33(12):2477-87.
2012: Ya-Ling Hsu; Po-Lin Kuo; In-Pin Lin; Eing-Mei Tsai; Chung-Yi Chen; Ming-Feng Hou
4-Shogaol, an active constituent of dietary ginger, inhibits metastasis of MDA-MB-231 human breast adenocarcinoma cells by decreasing the repression of NF-κB/Snail on RKIP.
Journal of agricultural and food chemistry 2012;60(3):852-61.
2012: Chang-Hung Kuo; Po-Lin Kuo; Ching-Hsiung Lin; Wan-Ju Wei; San-Nan Yang; Hsiu-Lin Chen; Yi-Pin Chen; Ya-Ling Hsu; Ming-Yii Huang; Shau-Ku Huang; Yuh-Jyh Jong; Chih-Hsing Hung
Effect of prostaglandin I2 analogs on cytokine expression in human myeloid dendritic cells via epigenetic regulation.
Molecular medicine (Cambridge, Mass.) 2012;18():433-44.
2011: Ya-Ling Hsu; Ming-Shyan Huang; Jen-Yu Hung; Ling-Yu Wu; Chih-Jen Yang; Po-Lin Kuo
Lung tumor-associated osteoblast-derived bone morphogenetic protein-2 increased epithelial-to-mesenchymal transition of cancer by Runx2/Snail signaling pathway.
The Journal of biological chemistry 2011;286(43):37335-46.
2011: Ya-Ling Hsu; Hsien-Chung Lin; Kwou-Yeung Wu; Rei-Cheng Yang; Hsin-Su Yu; Po-Lin Kuo
Heat shock induces apoptosis through reactive oxygen species involving mitochondrial and death receptor pathways in corneal cells.
Experimental eye research 2011;93(4):405-12.
2011: Ya-Ling Hsu; Ming-Shyan Huang; Jen-Yu Hung; Da-En Cheng; Shah-Hwa Chou; Chih-Jen Yang; Po-Lin Kuo
Lung tumor-associated dendritic cell-derived amphiregulin increased cancer progression.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(4):1733-44.
2011: Po-Lin Kuo; Ming-Ju Tsai; Ya-Ling Hsu; Ming-Shyan Huang
Pterostilbene suppresses benzo[a]pyrene-induced airway remodeling.
Journal of agricultural and food chemistry 2011;59(14):8028-35.
2011: Po-Lin Kuo; Yen-Hsu Chen; Tun-Chieh Chen; Kun-Hung Shen; Ya-Ling Hsu
CXCL5/ENA78 increased cell migration and epithelial-to-mesenchymal transition of hormone-independent prostate cancer by early growth response-1/snail signaling pathway.
Journal of cellular physiology 2011;226(5):1224-31.
2011: Po-Lin Kuo; Ming-Shyan Huang; Shau-Ku Huang; W-C Ni; J-Y Hung; Ying-Chin Ko; Chih-Hsing Hung; Y-M Tsai; T-H Duh; Ya-Ling Hsu
Signalling pathway of isophorone diisocyanate-responsive interleukin-8 in airway smooth muscle cells.
The European respiratory journal 2011;37(5):1226-36.
2011: Po-Lin Kuo; Ya-Ling Hsu; Ming-Shyan Huang; Ming-Ju Tsai; Ying-Chin Ko
Ginger suppresses phthalate ester-induced airway remodeling.
Journal of agricultural and food chemistry 2011;59(7):3429-38.
2011: A-Ching Chao; Ya-Ling Hsu; Ching-Kuan Liu; Po-Lin Kuo
α-Mangostin, a dietary xanthone, induces autophagic cell death by activating the AMP-activated protein kinase pathway in glioblastoma cells.
Journal of agricultural and food chemistry 2011;59(5):2086-96.
2011: Po-Lin Kuo; Jen-Yu Hung; Shau-Ku Huang; Shah-Hwa Chou; Da-En Cheng; Yuh-Jyh Jong; Chih-Hsing Hung; Chih-Jen Yang; Ying-Ming Tsai; Ya-Ling Hsu; Ming-Shyan Huang
Lung cancer-derived galectin-1 mediates dendritic cell anergy through inhibitor of DNA binding 3/IL-10 signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(3):1521-30.
2011: Ya-Ling Hsu; Ling-Yu Wu; Ming-Feng Hou; Eing-Mei Tsai; Jau-Nan Lee; Hsin-Lin Liang; Yuh-Jyh Jong; Chih-Hsing Hung; Po-Lin Kuo
Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway.
Molecular nutrition & food research 2011;55(2):318-27.
2010: Ya-Ling Hsu; Chung-Yi Chen; Ming-Feng Hou; Eing-Mei Tsai; Yuh-Jyh Jong; Chih-Hsing Hung; Po-Lin Kuo
6-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human breast cancer cells.
Molecular nutrition & food research 2010;54(9):1307-17.
2010: Jen-Yu Hung; Ya-Ling Hsu; Ying-Chin Ko; Ying-Ming Tsai; Chih-Jen Yang; Ming-Shyan Huang; Po-Lin Kuo
Didymin, a dietary flavonoid glycoside from citrus fruits, induces Fas-mediated apoptotic pathway in human non-small-cell lung cancer cells in vitro and in vivo.
Lung cancer (Amsterdam, Netherlands) 2010;68(3):366-74.
2010: Jen-Yu Hung; Ya-Ling Hsu; Wen-Chiu Ni; Ying-Ming Tsai; Chih-Jen Yang; Po-Lin Kuo; Ming-Shyan Huang
Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells.
Lung cancer (Amsterdam, Netherlands) 2010;68(3):355-65.
2009: Ya-Ling Hsu; Hsin-Lin Liang; Chih-Hsing Hung; Po-Lin Kuo
Syringetin, a flavonoid derivative in grape and wine, induces human osteoblast differentiation through bone morphogenetic protein-2/extracellular signal-regulated kinase 1/2 pathway.
Molecular nutrition & food research 2009;53(11):1452-61.
2009: Jen-Yu Hung; Ya-Ling Hsu; Chien-Te Li; Ying-Chin Ko; Wen-Chiu Ni; Ming-Shyan Huang; Po-Lin Kuo
6-Shogaol, an active constituent of dietary ginger, induces autophagy by inhibiting the AKT/mTOR pathway in human non-small cell lung cancer A549 cells.
Journal of agricultural and food chemistry 2009;57(20):9809-16.
2009: Ya-Ling Hsu; Yih-Huei Uen; Yi Chen; Hsin-Lin Liang; Po-Lin Kuo
Tricetin, a dietary flavonoid, inhibits proliferation of human breast adenocarcinoma mcf-7 cells by blocking cell cycle progression and inducing apoptosis.
Journal of agricultural and food chemistry 2009;57(18):8688-95.
2009: Ya-Ling Hsu; Chun-Chieh Chia; Ping-Jye Chen; Su-Er Huang; Soon-Cen Huang; Po-Lin Kuo
Shallot and licorice constituent isoliquiritigenin arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and initiation of the mitochondrial system in human cervical carcinoma HeLa cells.
Molecular nutrition & food research 2009;53(7):826-35.
2009: Po-Lin Kuo; Wen-Chiu Ni; Eing-Mei Tsai; Ya-Ling Hsu
Dehydrocostuslactone disrupts signal transducers and activators of transcription 3 through up-regulation of suppressor of cytokine signaling in breast cancer cells.
Molecular cancer therapeutics 2009;8(5):1328-39.
2009: Ya-Ling Hsu; Ling-Yu Wu; Po-Lin Kuo
Dehydrocostuslactone, a medicinal plant-derived sesquiterpene lactone, induces apoptosis coupled to endoplasmic reticulum stress in liver cancer cells.
The Journal of pharmacology and experimental therapeutics 2009;329(2):808-19.
2008: Ya-Ling Hsu; Po-Lin Kuo; Tz-Fei Tzeng; Shu-Chiao Sung; Ming-Hong Yen; Liang-Tzung Lin; Chun-Ching Lin
Huang-lian-jie-du-tang, a traditional Chinese medicine prescription, induces cell-cycle arrest and apoptosis in human liver cancer cells in vitro and in vivo.
Journal of gastroenterology and hepatology 2008;23(7 Pt 2):e290-9.
2008: Po-Lin Kuo; Chung-Yi Chen; Tz-Fei Tzeng; Chun-Ching Lin; Ya-Ling Hsu
Involvement of reactive oxygen species/c-Jun NH(2)-terminal kinase pathway in kotomolide A induces apoptosis in human breast cancer cells.
Toxicology and applied pharmacology 2008;229(2):215-26.
2008: Ya-Ling Hsu; Po-Lin Kuo
Diosmetin induces human osteoblastic differentiation through the protein kinase C/p38 and extracellular signal-regulated kinase 1/2 pathway.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008;23(6):949-60.
2008: Po-Lin Kuo; Ya-Ling Hsu
The grape and wine constituent piceatannol inhibits proliferation of human bladder cancer cells via blocking cell cycle progression and inducing Fas/membrane bound Fas ligand-mediated apoptotic pathway.
Molecular nutrition & food research 2008;52(4):408-18.
2007: Kun-Hung Shen; Jiunn-Kae Chang; Ya-Ling Hsu; Po-Lin Kuo
Chalcone arrests cell cycle progression and induces apoptosis through induction of mitochondrial pathway and inhibition of nuclear factor kappa B signalling in human bladder cancer cells.
Basic & clinical pharmacology & toxicology 2007;101(4):254-61.
2007: Po-Lin Kuo; Chung-Yi Chen; Ya-Ling Hsu
Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells.
Cancer research 2007;67(15):7406-20.
2007: Ya-Ling Hsu; Po-Lin Kuo; Chien-Yu Cho; Wen-Chiu Ni; Tz-Fei Tzeng; Lean-Teik Ng; Yueh-Hsiung Kuo; Chun-Ching Lin
Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/PRF/5 through inhibition of nuclear factor kappaB pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(7):1249-57.
2007: Po-Lin Kuo; Ya-Ling Hsu; Shu-Chiao Sung; Wen-Chiu Ni; Ta-Chen Lin; Chun-Ching Lin
Induction of apoptosis in human breast adenocarcinoma MCF-7 cells by pterocarnin A from the bark of Pterocarya stenoptera via the Fas-mediated pathway.
Anti-cancer drugs 2007;18(5):555-62.
2007: Po-Lin Kuo; Ya-Ling Hsu; Ta-Chen Lin; Wen-Sheng Tzeng; Yin-Yi Chen; Chun-Ching Lin
Rugosin E, an ellagitannin, inhibits MDA-MB-231 human breast cancer cell proliferation and induces apoptosis by inhibiting nuclear factor-kappaB signaling pathway.
Cancer letters 2007;248(2):280-91.
2007: Ya-Ling Hsu; Jiunn-Kae Chang; Chu-Hung Tsai; Tzu-Tsung Chang Chien; Po-Lin Kuo
Myricetin induces human osteoblast differentiation through bone morphogenetic protein-2/p38 mitogen-activated protein kinase pathway.
Biochemical pharmacology 2007;73(4):504-14.
2006: Jiunn-Kae Chang; Ya-Ling Hsu; I-Chun Teng; Po-Lin Kuo
Piceatannol stimulates osteoblast differentiation that may be mediated by increased bone morphogenetic protein-2 production.
European journal of pharmacology 2006;551(1-3):1-9.
2006: Po-Lin Kuo; Ya-Ling Hsu; Chien-Yu Cho
Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells.
Molecular cancer therapeutics 2006;5(12):3209-21.
2006: Ya-Ling Hsu; Ming-Hong Yen; Po-Lin Kuo; Chien-Yu Cho; Yu-Ting Huang; Chien-Jung Tseng; Ju-Ping Lee; Chun-Ching Lin
San-Zhong-Kui-Jian-Tang, a traditional Chinese medicine prescription, inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis.
Biological & pharmaceutical bulletin 2006;29(12):2388-94.
2006: Ya-Ling Hsu; Chien-Yu Cho; Po-Lin Kuo; Yu-Ting Huang; Chun-Ching Lin
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo.
The Journal of pharmacology and experimental therapeutics 2006;318(2):484-94.
2006: Po-Lin Kuo; Ya-Ling Hsu; Chien-Yu Cho; Lean-Teik Ng; Yueh-Hsiung Kuo; Chun-Ching Lin
Apoptotic effects of Antrodia cinnamomea fruiting bodies extract are mediated through calcium and calpain-dependent pathways in Hep 3B cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(8):1316-26.
2006: Po-Lin Kuo; Chien-Yu Cho; Ya-Ling Hsu; Ta-Chen Lin; Chun-Ching Lin
Putranjivain A from Euphorbia jolkini inhibits proliferation of human breast adenocarcinoma MCF-7 cells via blocking cell cycle progression and inducing apoptosis.
Toxicology and applied pharmacology 2006;213(1):37-45.
2006: Ya-Ling Hsu; Po-Lin Kuo; W S Tzeng; Chun-Ching Lin
Chalcone inhibits the proliferation of human breast cancer cell by blocking cell cycle progression and inducing apoptosis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(5):704-13.
2006: Yu-Chun Kuo; Po-Lin Kuo; Ya-Ling Hsu; Chien-Yu Cho; Chun-Ching Lin
Ellipticine induces apoptosis through p53-dependent pathway in human hepatocellular carcinoma HepG2 cells.
Life sciences 2006;78(22):2550-7.
2005: Po-Lin Kuo; Ya-Ling Hsu; Cheng-Hsiung Chang; Jiunn-Kae Chang
Osthole-mediated cell differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway in human osteoblast cells.
The Journal of pharmacology and experimental therapeutics 2005;314(3):1290-9.
2005: Po-Lin Kuo; Ya-Ling Hsu; Yu-Chun Kuo; Cheng-Hsiung Chang; Chun-Ching Lin
The anti-proliferative inhibition of ellipticine in human breast mda-mb-231 cancer cells is through cell cycle arrest and apoptosis induction.
Anti-cancer drugs 2005;16(7):789-95.
2005: Po-Lin Kuo; Ya-Ling Hsu; Cheng-Hsiung Chang; Chun-Ching Lin
The mechanism of ellipticine-induced apoptosis and cell cycle arrest in human breast MCF-7 cancer cells.
Cancer letters 2005;223(2):293-301.
2005: Ya-Ling Hsu; Po-Lin Kuo; Chun-Ching Lin
Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cells.
Life sciences 2005;77(3):279-92.
2005: Ya-Ling Hsu; Yu-Chun Kuo; Po-Lin Kuo; Lean-Teik Ng; Yueh-Hsiung Kuo; Chun-Ching Lin
Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell lines.
Cancer letters 2005;221(1):77-89.
2005: Po-Lin Kuo; Ya-Ling Hsu; Ta-Chen Lin; Jiunn-Kae Chang; Chun-Ching Lin
Induction of cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells by casuarinin from the bark of Terminalia arjuna Linn.
Anti-cancer drugs 2005;16(4):409-15.
2005: Ya-Ling Hsu; Po-Lin Kuo; Liang-Tzung Lin; Chun-Ching Lin
Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells.
The Journal of pharmacology and experimental therapeutics 2005;313(1):333-44.
2005: Po-Lin Kuo; Ya-Ling Hsu; Ta-Chen Lin; Liang-Tzung Lin; Jiunn-Kae Chang; Chun-Ching Lin
Casuarinin from the bark of Terminalia arjuna induces apoptosis and cell cycle arrest in human breast adenocarcinoma MCF-7 cells.
Planta medica 2005;71(3):237-43.
2005: Ya-Ling Hsu; Po-Lin Kuo; Liang-Tzung Lin; Chun-Ching Lin
Isoliquiritigenin inhibits cell proliferation and induces apoptosis in human hepatoma cells.
Planta medica 2005;71(2):130-4.
2005: Po-Lin Kuo; Ya-Ling Hsu; Ta-Chen Lin; Chun-Ching Lin
The antiproliferative activity of prodelphinidin B-2 3'-O-gallate from green tea leaf is through cell cycle arrest and Fas-mediated apoptotic pathway in A549 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2005;43(2):315-23.
2004: Po-Lin Kuo; Ya-Ling Hsu; Ta-Chen Lin; Liang-Tzung Lin; Chun-Ching Lin
Induction of apoptosis in human breast adenocarcinoma MCF-7 cells by prodelphinidin B-2 3,3'-di-O-gallate from Myrica rubra via Fas-mediated pathway.
The Journal of pharmacy and pharmacology 2004;56(11):1399-406.
2004: Po-Lin Kuo; Ya-Ling Hsu; Ta-Chen Lin; Chun-Ching Lin
Prodelphinidin B-2 3,3'-di-O-gallate from Myrica rubra inhibits proliferation of A549 carcinoma cells via blocking cell cycle progression and inducing apoptosis.
European journal of pharmacology 2004;501(1-3):41-8.
2004: Ya-Ling Hsu; Po-Lin Kuo; Lien-Chai Chiang; Chun-Ching Lin
Involvement of p53, nuclear factor kappaB and Fas/Fas ligand in induction of apoptosis and cell cycle arrest by saikosaponin d in human hepatoma cell lines.
Cancer letters 2004;213(2):213-21.
2004: Ya-Ling Hsu; Po-Lin Kuo; Chun-Ching Lin
Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cells.
Life sciences 2004;75(19):2303-16.
2004: Ya-Ling Hsu; Po-Lin Kuo; Chi-Feng Liu; Chun-Ching Lin
Acacetin-induced cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells.
Cancer letters 2004;212(1):53-60.
2004: Ya-Ling Hsu; Po-Lin Kuo; Chun-Ching Lin
The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cells.
Life sciences 2004;75(10):1231-42.
2004: Ya-Ling Hsu; Po-Lin Kuo; Ting-Chun Weng; Ming-Hong Yen; Lien-Chai Chiang; Chun-Ching Lin
The antiproliferative activity of saponin-enriched fraction from Bupleurum Kaoi is through Fas-dependent apoptotic pathway in human non-small cell lung cancer A549 cells.
Biological & pharmaceutical bulletin 2004;27(7):1112-5.
2004: Ya-Ling Hsu; Po-Lin Kuo; Lien-Chai Chiang; Chun-Ching Lin
Isoliquiritigenin inhibits the proliferation and induces the apoptosis of human non-small cell lung cancer a549 cells.
Clinical and experimental pharmacology & physiology 2004;31(7):414-8.
2004: Ya-Ling Hsu; Po-Lin Kuo; Chun-Ching Lin
Acacetin inhibits the proliferation of Hep G2 by blocking cell cycle progression and inducing apoptosis.
Biochemical pharmacology 2004;67(5):823-9.
2004: Po-Lin Kuo; Ya-Ling Hsu; Lean-Teik Ng; Chun-Ching Lin
Rhein inhibits the growth and induces the apoptosis of Hep G2 cells.
Planta medica 2004;70(1):12-6.