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Fen Ze Hu

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Azad Ahmed; Robert Boissy; Thomas L Cherpes; J William Costerton; Margaret E Dahlgren; Josh Earl; Rory Eutsey; Barry G Hall; N Luisa Hiller; Sharon L Hillier; Fen Ze Hu; Benjamin Janto; J Christopher Post; Evan Powell; Lorna K Rabe; Adam Retchless; Garth D Ehrlich
Comparative genomic analyses of 17 clinical isolates of Gardnerella vaginalis provide evidence of multiple genetically isolated clades consistent with subspeciation into genovars.
Fen Ze Hu; Benjamin Janto; Jennifer Kress-Bennett; Mark Longwell; Mirjana Nesin; J Christopher Post; Evan Powell; Alexander Tomasz; Azad Ahmed; Robert Boissy; Farrel Buchinsky; Rory Eutsey; Suzanne Ezzo; Nelson Frazao; N Luisa Hiller; Todd Hillman; Garth D Ehrlich
In vivo capsular switch in Streptococcus pneumoniae--analysis by whole genome sequencing.
John William Costerton; J Christopher Post; Garth D Ehrlich; Fen Ze Hu; Rachael Kreft; Laura Nistico; Sandeep Kathju; Paul Stoodley; Luanne Hall-Stoodley; Gerhard Maale; Garth James; Nick Sotereanos; Patrick DeMeo
New methods for the detection of orthopedic and other biofilm infections.

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All Publications

2012: Azad Ahmed; Robert Boissy; Thomas L Cherpes; J William Costerton; Margaret E Dahlgren; Josh Earl; Rory Eutsey; Barry G Hall; N Luisa Hiller; Sharon L Hillier; Fen Ze Hu; Benjamin Janto; J Christopher Post; Evan Powell; Lorna K Rabe; Adam Retchless; Garth D Ehrlich
Comparative genomic analyses of 17 clinical isolates of Gardnerella vaginalis provide evidence of multiple genetically isolated clades consistent with subspeciation into genovars.
Journal of bacteriology 2012;194(15):3922-37.
2012: Fen Ze Hu; Benjamin Janto; Jennifer Kress-Bennett; Mark Longwell; Mirjana Nesin; J Christopher Post; Evan Powell; Alexander Tomasz; Azad Ahmed; Robert Boissy; Farrel Buchinsky; Rory Eutsey; Suzanne Ezzo; Nelson Frazao; N Luisa Hiller; Todd Hillman; Garth D Ehrlich
In vivo capsular switch in Streptococcus pneumoniae--analysis by whole genome sequencing.
PloS one 2012;7(11):e47983.
2011: John William Costerton; J Christopher Post; Garth D Ehrlich; Fen Ze Hu; Rachael Kreft; Laura Nistico; Sandeep Kathju; Paul Stoodley; Luanne Hall-Stoodley; Gerhard Maale; Garth James; Nick Sotereanos; Patrick DeMeo
New methods for the detection of orthopedic and other biofilm infections.
FEMS immunology and medical microbiology 2011;61(2):133-40.
2010: Garth D Ehrlich; Azad Ahmed; Josh Earl; N Luisa Hiller; J William Costerton; Paul Stoodley; J Christopher Post; Patrick DeMeo; Fen Ze Hu
The distributed genome hypothesis as a rubric for understanding evolution in situ during chronic bacterial biofilm infectious processes.
FEMS immunology and medical microbiology 2010;59(3):269-79.
2010: Shichun Cai; Jiabao Li; Fen Ze Hu; Kegui Zhang; Yuanming Luo; Benjamin Janto; Robert Boissy; Garth Ehrlich; Xiuzhu Dong
Cellulosilyticum ruminicola, a newly described rumen bacterium that possesses redundant fibrolytic-protein-encoding genes and degrades lignocellulose with multiple carbohydrate- borne fibrolytic enzymes.
Applied and environmental microbiology 2010;76(12):3818-24.
2010: Joseph E Kerschner; Geza Erdos; Fen Ze Hu; Amy Burrows; Joseph A Cioffi; Pawjai Khampang; Margaret Dahlgren; Jay Hayes; Randy Keefe; Benjamin Janto; J Christopher Post; Garth D Ehrlich
Partial characterization of normal and Haemophilus influenzae-infected mucosal complementary DNA libraries in chinchilla middle ear mucosa.
The Annals of otology, rhinology, and laryngology 2010;119(4):270-8.
2010: Claudio Donati; N Luisa Hiller; Hervé Tettelin; Alessandro Muzzi; Nicholas J Croucher; Samuel V Angiuoli; Marco Oggioni; Julie C Hotopp; Fen Ze Hu; David R Riley; Antonello Covacci; Tim Mitchell; Stephen D Bentley; Morgens Kilian; Garth D Ehrlich; Rino Rappuoli; E Richard Moxon; Vega Masignani
Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species.
Genome biology 2010;11(10):R107.
2010: N Luisa Hiller; Azad Ahmed; Evan Powell; Darren P Martin; Rory Eutsey; Josh Earl; Benjamin Janto; Robert J Boissy; Justin Hogg; Karen Barbadora; Rangarajan Sampath; Shaun Lonergan; J Christopher Post; Fen Ze Hu; Garth D Ehrlich
Generation of genic diversity among Streptococcus pneumoniae strains via horizontal gene transfer during a chronic polyclonal pediatric infection.
PLoS pathogens 2010;6(9):e1001108.
2009: K Shen; S M Krakora; M Cunningham; M Singh; X Wang; Fen Ze Hu; J Christopher Post; Garth D Ehrlich
Medical treatment of craniosynostosis: recombinant Noggin inhibits coronal suture closure in the rat craniosynostosis model.
Orthodontics & craniofacial research 2009;12(3):254-62.
2009: Bethany Dice; Paul Stoodley; Farrel Buchinsky; Nalini Metha; Garth D Ehrlich; Fen Ze Hu
Biofilm formation by ica-positive and ica-negative strains of Staphylococcus epidermidis in vitro.
Biofouling 2009;25(4):367-75.
2009: Joseph E Kerschner; Edward Horsey; Azad Ahmed; Christy Erbe; Pawjai Khampang; Joseph A Cioffi; Fen Ze Hu; James Christopher Post; Garth D Ehrlich
Gene expression differences in infected and noninfected middle ear complementary DNA libraries.
Archives of otolaryngology--head & neck surgery 2009;135(1):33-9.
2008: Latha Satish; Adam Abdulally; Duane Oswald; Sandra Johnson; Fen Ze Hu; J Christopher Post; Garth D Ehrlich; Sandeep Kathju
Differential expression of chaperonin containing T-complex polypeptide (CCT) subunits during fetal and adult skin wound healing.
Cell stress & chaperones 2008;13(4):527-33.
2008: Fen Ze Hu; Garth D Ehrlich
Population-level virulence factors amongst pathogenic bacteria: relation to infection outcome.
Future microbiology 2008;3(1):31-42.
2008: Garth D Ehrlich; N Luisa Hiller; Fen Ze Hu
What makes pathogens pathogenic.
Genome biology 2008;9(6):225.
2008: Farrel Buchinsky; Joseph Donfack; Craig S Derkay; Sukgi S Choi; Stephen F Conley; Charles M Myer; John McClay; Paolo Campisi; Brian J Wiatrak; Steven E Sobol; John M Schweinfurth; Domingos H Tsuji; Fen Ze Hu; Howard E Rockette; Garth D Ehrlich; J Christopher Post
Age of child, more than HPV type, is associated with clinical course in recurrent respiratory papillomatosis.
PloS one 2008;3(5):e2263.
2008: Latha Satish; William A LaFramboise; David B O'Gorman; Sandra Johnson; Benjamin Janto; Bing Siang Gan; Mark E Baratz; Fen Ze Hu; J Christopher Post; Garth D Ehrlich; Sandeep Kathju
Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren's Contracture.
BMC medical genomics 2008;1():10.
2008: MICHAEL LEIGHTON FORBES; Edward Horsey; N Luisa Hiller; Farrel Buchinsky; Jay D Hayes; James M Compliment; Todd Hillman; Suzanne Ezzo; Kai Shen; Randy Keefe; Karen Barbadora; J Christopher Post; Fen Ze Hu; Garth D Ehrlich
Strain-specific virulence phenotypes of Streptococcus pneumoniae assessed using the Chinchilla laniger model of otitis media.
PloS one 2008;3(4):e1969.
2007: N Luisa Hiller; Benjamin Janto; Justin S Hogg; Robert Boissy; Susan Yu; Evan Powell; Randy Keefe; Nathan Ehrlich; Kai Shen; Jay Hayes; Karen Barbadora; William Klimke; Dmitry Dernovoy; Tatiana Tatusova; Julian Parkhill; Stephen D Bentley; J Christopher Post; Garth D Ehrlich; Fen Ze Hu
Comparative genomic analyses of seventeen Streptococcus pneumoniae strains: insights into the pneumococcal supragenome.
Journal of bacteriology 2007;189(22):8186-95.
2007: Marc Mussmann; Fen Ze Hu; Michael Richter; Dirk de Beer; André Preisler; Bo Barker Jørgensen; Marcel Huntemann; Frank Oliver Glöckner; Rudolf Amann; Werner J H Koopman; Roger S Lasken; Benjamin Janto; Justin Hogg; Paul Stoodley; Robert Boissy; Garth D Ehrlich
Insights into the genome of large sulfur bacteria revealed by analysis of single filaments.
PLoS biology 2007;5(9):e230.
2007: M K Singh; T F Scott; W A LaFramboise; Fen Ze Hu; J Christopher Post; Garth D Ehrlich
Gene expression changes in peripheral blood mononuclear cells from multiple sclerosis patients undergoing beta-interferon therapy.
Journal of the neurological sciences 2007;258(1-2):52-9.
2007: Farrel Buchinsky; MICHAEL LEIGHTON FORBES; Jay D Hayes; Kai Shen; Suzanne Ezzo; James M Compliment; Justin Hogg; N Luisa Hiller; Fen Ze Hu; J Christopher Post; Garth D Ehrlich
Virulence phenotypes of low-passage clinical isolates of nontypeable Haemophilus influenzae assessed using the chinchilla laniger model of otitis media.
BMC microbiology 2007;7():56.
2007: Justin S Hogg; Fen Ze Hu; Benjamin Janto; Robert Boissy; Jay Hayes; Randy Keefe; J Christopher Post; Garth D Ehrlich
Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains.
Genome biology 2007;8(6):R103.
2006: Geza Erdos; Sameera Sayeed; Fen Ze Hu; Patricia Antalis; Kai Shen; Jay D Hayes; Azad I Ahmed; Sandra L Johnson; J Christopher Post; Garth D Ehrlich
Construction and characterization of a highly redundant Pseudomonas aeruginosa genomic library prepared from 12 clinical isolates: application to studies of gene distribution among populations.
International journal of pediatric otorhinolaryngology 2006;70(11):1891-900.
2006: Kai Shen; Sameera Sayeed; Patricia Antalis; John Gladitz; Azad Ahmed; Bethany Dice; Benjamin Janto; richard dopico; Randy Keefe; Jay Hayes; Sandra Johnson; Sujun Yu; Nathan Ehrlich; Jennifer Jocz; Laura Kropp; Ray Wong; Robert M Wadowsky; Malcolm Slifkin; Robert A Preston; Geza Erdos; J Christopher Post; Garth D Ehrlich; Fen Ze Hu
Extensive genomic plasticity in Pseudomonas aeruginosa revealed by identification and distribution studies of novel genes among clinical isolates.
Infection and immunity 2006;74(9):5272-83.
2006: Luanne Hall-Stoodley; Fen Ze Hu; Armin Gieseke; Laura Nistico; Duc Nguyen; Jay Hayes; Michael Forbes; David P Greenberg; Bethany Dice; Amy Burrows; P Ashley Wackym; Paul Stoodley; J Christopher Post; Garth D Ehrlich; Joseph E Kerschner
Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media.
JAMA : the journal of the American Medical Association 2006;296(2):202-11.
2006: Sandeep Kathju; Latha Satish; Cara Rabik; Terra Rupert; Duane Oswald; Sandra Johnson; Fen Ze Hu; J Christopher Post; Garth D Ehrlich
Identification of differentially expressed genes in scarless wound healing utilizing polymerase chain reaction-suppression subtractive hybridization.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2006;14(4):413-20.
2006: Joseph Donfack; Farrel Buchinsky; Craig S Derkay; Bettie Steinberg; Sukgi S Choi; Stephen F Conley; Charles M Meyer; John McClay; Paolo Campisi; Fen Ze Hu; Robert A Preston; Allan Abramson; Garth D Ehrlich; J Christopher Post
Four mutations in Epidermodysplasia verruciformis 1 (EVER1) gene are not contributors to susceptibility in RRP.
International journal of pediatric otorhinolaryngology 2006;70(7):1235-40.
2006: Magee Allegrucci; Fen Ze Hu; K Shen; J Hayes; Garth D Ehrlich; J Christopher Post; Karin Sauer
Phenotypic characterization of Streptococcus pneumoniae biofilm development.
Journal of bacteriology 2006;188(7):2325-35.
2006: Kai Shen; John Gladitz; Patricia Antalis; Bethany Dice; Benjamin Janto; Randy Keefe; Jay Hayes; Azad Ahmed; richard dopico; Nathan Ehrlich; Jennifer Jocz; Laura Kropp; Shujun Yu; Laura Nistico; David P Greenberg; Karen Barbadora; Robert A Preston; J Christopher Post; Garth D Ehrlich; Fen Ze Hu
Characterization, distribution, and expression of novel genes among eight clinical isolates of Streptococcus pneumoniae.
Infection and immunity 2006;74(1):321-30.
2005: Fen Ze Hu; A Nystrom; Azad Ahmed; M Palmquist; richard dopico; I Mossberg; John Gladitz; MG Rayner; J Christopher Post; Garth D Ehrlich; Robert A Preston
Mapping of an autosomal dominant gene for Dupuytren's contracture to chromosome 16q in a Swedish family.
Clinical genetics 2005;68(5):424-9.
2005: Ernest E Braxton; Garth D Ehrlich; Luanne Hall-Stoodley; Paul Stoodley; Richard Veeh; Christoph A Fux; Fen Ze Hu; Matthew Quigley; J Christopher Post
Role of biofilms in neurosurgical device-related infections.
Neurosurgical review 2005;28(4):249-55.
2005: Garth D Ehrlich; Paul Stoodley; Sandeep Kathju; Yongjun Zhao; Bruce R McLeod; Naomi Balaban; Fen Ze Hu; Nicholas G Sotereanos; J William Costerton; Philip S Stewart; J Christopher Post; Qiao Lin
Engineering approaches for the detection and control of orthopaedic biofilm infections.
Clinical orthopaedics and related research 2005;(437):59-66.
2005: Paul Stoodley; Sandeep Kathju; Fen Ze Hu; Geza Erdos; Joshua E Levenson; Nalini Mehta; Bethany Dice; Sandy Johnson; Luanne Hall-Stoodley; Laura Nistico; Nicholas G Sotereanos; Jeffrey J Sewecke; J Christopher Post; Garth D Ehrlich
Molecular and imaging techniques for bacterial biofilms in joint arthroplasty infections.
Clinical orthopaedics and related research 2005;(437):31-40.
2005: Garth D Ehrlich; Fen Ze Hu; Kai Shen; Paul Stoodley; J Christopher Post
Bacterial plurality as a general mechanism driving persistence in chronic infections.
Clinical orthopaedics and related research 2005;(437):20-4.
2005: Kai Shen; Patricia Antalis; John Gladitz; Sameera Sayeed; Azad Ahmed; Shujun Yu; Jay Hayes; Sandra Johnson; Bethany Dice; richard dopico; Randy Keefe; Benjamin Janto; William Chong; Joseph Goodwin; Robert M Wadowsky; Geza Erdos; J Christopher Post; Garth D Ehrlich; Fen Ze Hu
Identification, distribution, and expression of novel genes in 10 clinical isolates of nontypeable Haemophilus influenzae.
Infection and immunity 2005;73(6):3479-91.
2005: John Gladitz; Kai Shen; Patricia Antalis; Fen Ze Hu; J Christopher Post; Garth D Ehrlich
Codon usage comparison of novel genes in clinical isolates of Haemophilus influenzae.
Nucleic acids research 2005;33(11):3644-58.
2004: Songshan Jiang; Jordan Gitlin; Fang-Ming Deng; Feng-Xia Liang; Andy Lee; Anthony Atala; Stuart B Bauer; Garth D Ehrlich; Sally A Feather; Judith D Goldberg; Judith A Goodship; Timothy H J Goodship; Monika Hermanns; Fen Ze Hu; Katrin E Jones; Sue Malcolm; Cathy Mendelsohn; Robert A Preston; Alan B Retik; Francis X Schneck; Victoria Wright; Xiang Y Ye; Adrian S Woolf; Xue-Ru Wu; Harry Ostrer; Ellen Shapiro; Jun Yu; Tung-Tien Sun
Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity.
Kidney international 2004;66(1):10-9.
2004: Fen Ze Hu; Joseph Donfack; Azad Ahmed; richard dopico; Sandra Johnson; J Christopher Post; Garth D Ehrlich; Robert A Preston
Fine mapping a gene for pediatric gastroesophageal reflux on human chromosome 13q14.
Human genetics 2004;114(6):562-72.
2003: Geza Erdos; Sameera Sayeed; Patricia Antalis; Fen Ze Hu; Jay Hayes; Joseph Goodwin; richard dopico; J Christopher Post; Garth D Ehrlich
Development and characterization of a pooled Haemophilus influenzae genomic library for the evaluation of gene expression changes associated with mucosal biofilm formation in otitis media.
International journal of pediatric otorhinolaryngology 2003;67(7):749-55.
2002: Garth D Ehrlich; Richard Veeh; Xue Wang; J William Costerton; Jay D Hayes; Fen Ze Hu; Bernie J Daigle; Miles D Ehrlich; J Christopher Post
Mucosal biofilm formation on middle-ear mucosa in the chinchilla model of otitis media.
JAMA : the journal of the American Medical Association 2002;287(13):1710-5.
2001: C Heike; Marianne L Seto; Anne V Hing; A Palidin; Fen Ze Hu; R A Preston; Garth D Ehrlich; Michael L Cunningham
Century of Jackson-Weiss syndrome: further definition of clinical and radiographic findings in "lost" descendants of the original kindred.
American journal of medical genetics 2001;100(4):315-24.
2001: G M Dry; Y I Yasinskaya; J Kerwin Williams; Garth D Ehrlich; R A Preston; Fen Ze Hu; Joseph S Gruss; Richard G Ellenbogen; Michael L Cunningham
Inhibition of apoptosis: a potential mechanism for syndromic craniosynostosis.
Plastic and reconstructive surgery 2001;107(2):425-32.
2000: Fen Ze Hu; J Christopher Post; Sandra Johnson; Garth D Ehrlich; Robert A Preston
Refined localization of a gene for pediatric gastroesophageal reflux makes HTR2A an unlikely candidate gene.
Human genetics 2000;107(5):519-25.
2000: Fen Ze Hu; Robert A Preston; J Christopher Post; GJ White; L W Kikuchi; X Wang; S M Leal; M A Levenstien; J Ott; T W Self; G Allen; R S Stiffler; C McGraw; E A Pulsifer-Anderson; Garth D Ehrlich
Mapping of a gene for severe pediatric gastroesophageal reflux to chromosome 13q14.
JAMA : the journal of the American Medical Association 2000;284(3):325-34.
2000: D L Darden; Fen Ze Hu; Miles D Ehrlich; Michael C Gorry; D Dressman; H S Li; david whitcomb; Patricia A Hebda; Joseph E Dohar; Garth D Ehrlich
RNA differential display of scarless wound healing in fetal rabbit indicates downregulation of a CCT chaperonin subunit and upregulation of a glycophorin-like gene transcript.
Journal of pediatric surgery 2000;35(3):406-19.