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Michel Aubert

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emmanuel somm; Audrey Toulotte; Nicolas Bonnet; Verity A Cadd; Mark Elliott; Serge L Ferrari; Elaine Harper; Petra S Hüppi; Richard Jones; Philip M H Marks; Alberto Martinez; Shlomo Melmed; René Rizzoli; Michel L Aubert
A botulinum toxin-derived targeted secretion inhibitor downregulates the GH/IGF1 axis.
emmanuel somm; Audrey Toulotte; Delphine M Vauthay; Michel L Aubert; Philippe Cettour-Rose; Audrey Guérardel; Petra S Hüppi; Philippe Klee; Paolo Meda; Valerie M Schwitzgebel
Early metabolic defects in dexamethasone-exposed and undernourished intrauterine growth restricted rats.
emmanuel somm; Valérie M Schwitzgebel; Audrey Toulotte; Christopher R Cederroth; Christophe Combescure; Serge Nef; Michel L Aubert; Petra S Hüppi
Perinatal exposure to bisphenol a alters early adipogenesis in the rat.

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2012: emmanuel somm; Audrey Toulotte; Nicolas Bonnet; Verity A Cadd; Mark Elliott; Serge L Ferrari; Elaine Harper; Petra S Hüppi; Richard Jones; Philip M H Marks; Alberto Martinez; Shlomo Melmed; René Rizzoli; Michel L Aubert
A botulinum toxin-derived targeted secretion inhibitor downregulates the GH/IGF1 axis.
The Journal of clinical investigation 2012;122(9):3295-306.
2012: emmanuel somm; Audrey Toulotte; Delphine M Vauthay; Michel L Aubert; Philippe Cettour-Rose; Audrey Guérardel; Petra S Hüppi; Philippe Klee; Paolo Meda; Valerie M Schwitzgebel
Early metabolic defects in dexamethasone-exposed and undernourished intrauterine growth restricted rats.
PloS one 2012;7(11):e50131.
2009: emmanuel somm; Valérie M Schwitzgebel; Audrey Toulotte; Christopher R Cederroth; Christophe Combescure; Serge Nef; Michel L Aubert; Petra S Hüppi
Perinatal exposure to bisphenol a alters early adipogenesis in the rat.
Environmental health perspectives 2009;117(10):1549-55.
2004: Eiva Bernotiene; Gaby Palmer; Dominique Talabot-Ayer; Ildiko Szalay-Quinodoz; Michel L Aubert; Cem Gabay
Delayed resolution of acute inflammation during zymosan-induced arthritis in leptin-deficient mice.
Arthritis research & therapy 2004;6(3):R256-63.
2004: Paula D Raposinho; Thierry Pedrazzini; Richard B White; Richard D Palmiter; Michel L Aubert
Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression.
Endocrinology 2004;145(1):304-10.
2003: Paula D Raposinho; Richard B White; Michel L Aubert
The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat.
Journal of neuroendocrinology 2003;15(2):173-81.
2002: Béatrice Sudre; Pierre Broqua; Richard B White; Doreen Ashworth; D Michael Evans; Robert Haigh; Jean-Louis Junien; Michel L Aubert
Chronic inhibition of circulating dipeptidyl peptidase IV by FE 999011 delays the occurrence of diabetes in male zucker diabetic fatty rats.
Diabetes 2002;51(5):1461-9.
2002: Pierre Broqua; Pierre J-M Riviere; P Michael Conn; Jean E Rivier; Michel L Aubert; Jean-Louis Junien
Pharmacological profile of a new, potent, and long-acting gonadotropin-releasing hormone antagonist: degarelix.
The Journal of pharmacology and experimental therapeutics 2002;301(1):95-102.
2001: Paula D Raposinho; DD Pierroz; Pierre Broqua; Richard B White; Thierry Pedrazzini; Michel L Aubert
Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism.
Molecular and cellular endocrinology 2001;185(1-2):195-204.
2001: G Jiang; J Stalewski; R Galyean; John Dykert; Claudio D Schteingart; Pierre Broqua; AC Aebi; Michel L Aubert; G Semple; P Robson; Karen Akinsanya; R Haigh; Pierre J-M Riviere; Jerzy Trojnar; Jean-Louis Junien; Jean E Rivier
GnRH antagonists: a new generation of long acting analogues incorporating p-ureido-phenylalanines at positions 5 and 6.
Journal of medicinal chemistry 2001;44(3):453-67.
2000: Paula D Raposinho; Einar Castillo; V d'Alleves; Pierre Broqua; François P Pralong; Michel L Aubert
Chronic blockade of the melanocortin 4 receptor subtype leads to obesity independently of neuropeptide Y action, with no adverse effects on the gonadotropic and somatotropic axes.
Endocrinology 2000;141(12):4419-27.
2000: Paula D Raposinho; Pierre Broqua; A Hayward; Karen Akinsanya; R Galyean; Claudio D Schteingart; Jean-Louis Junien; Michel L Aubert
Stimulation of the gonadotropic axis by the neuropeptide Y receptor Y1 antagonist/Y4 agonist 1229U91 in the male rat.
Neuroendocrinology 2000;71(1):2-7.
1999: François P Pralong; F Gomez; Einar Castillo; S Cotecchia; Liliane Abuin; Michel L Aubert; Luc Portmann; Rolf C Gaillard
Complete hypogonadotropic hypogonadism associated with a novel inactivating mutation of the gonadotropin-releasing hormone receptor.
The Journal of clinical endocrinology and metabolism 1999;84(10):3811-6.
1999: Paula D Raposinho; Pierre Broqua; DD Pierroz; Anthony R Hayward; Y Dumont; R Quirion; Jean-Louis Junien; Michel L Aubert
Evidence that the inhibition of luteinizing hormone secretion exerted by central administration of neuropeptide Y (NPY) in the rat is predominantly mediated by the NPY-Y5 receptor subtype.
Endocrinology 1999;140(9):4046-55.
1999: DD Pierroz; AC Aebi; I T Huhtaniemi; Michel L Aubert
Many LH peaks are needed to physiologically stimulate testosterone secretion: modulation by fasting and NPY.
The American journal of physiology 1999;276(4 Pt 1):E603-10.
1998: NM Gruaz; M Lalaoui; DD Pierroz; P Englaro; P C Sizonenko; WF Blum; Michel L Aubert
Chronic administration of leptin into the lateral ventricle induces sexual maturation in severely food-restricted female rats.
Journal of neuroendocrinology 1998;10(8):627-33.
1998: Michel L Aubert; DD Pierroz; NM Gruaz; V d'Allèves; BA Vuagnat; François P Pralong; WF Blum; P C Sizonenko
Metabolic control of sexual function and growth: role of neuropeptide Y and leptin.
Molecular and cellular endocrinology 1998;140(1-2):107-13.
1998: BA Vuagnat; DD Pierroz; M Lalaoui; P Englaro; François P Pralong; WF Blum; Michel L Aubert
Evidence for a leptin-neuropeptide Y axis for the regulation of growth hormone secretion in the rat.
Neuroendocrinology 1998;67(5):291-300.
1998: Michel L Aubert
1997 ESPE Research Award. Regulation of sexual maturation in the rat: the search for the neuromodulator that controls the onset of puberty. European Society for Paediatric Endocrinology.
Hormone research 1998;50(1):55-6.
1997: NM Gruaz; V d'Allèves; Yves Charnay; A Skotther; S Ekvärn; L Fryklund; Michel L Aubert
Effects of constant infusion with insulin-like growth factor-I (IGF-I) to immature female rats on body weight gain, tissue growth, and sexual function : Evidence that such treatment does not affect sexual maturation or fertility.
Endocrine 1997;6(1):11-9.
1997: NM Gruaz; V d'Allèves; Yves Charnay; A Skottner; S Ekvärn; L Fryklund; Michel L Aubert
Effects of constant infusion with insulin-like growth factor-I (IGF-I) to immature female rats on body weight gain, tissue growth and sexual function. Evidence that such treatment does not affect sexual maturation of fertility.
Endocrine 1997;6(1):11-9.
1996: Michel L Aubert; PC Sizonenko
Environmental factors and sexual maturation in rodents.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1996;417():86-8.
1996: DD Pierroz; C Catzeflis; AC Aebi; J E Rivier; Michel L Aubert
Chronic administration of neuropeptide Y into the lateral ventricle inhibits both the pituitary-testicular axis and growth hormone and insulin-like growth factor I secretion in intact adult male rats.
Endocrinology 1996;137(1):3-12.
1995: DD Pierroz; N M Gruaz; V d'Alièves; Michel L Aubert
Chronic administration of neuropeptide Y into the lateral ventricle starting at 30 days of life delays sexual maturation in the female rat.
Neuroendocrinology 1995;61(3):293-300.
1994: N M Gruaz; Yvan Arsenijevic; W B Wehrenberg; PC Sizonenko; Michel L Aubert
Growth hormone (GH) deprivation induced by passive immunization against rat GH-releasing factor does not disturb the course of sexual maturation and fertility in the female rat.
Endocrinology 1994;135(2):509-19.
1994: Senlin Li; B Vuagnat; N M Gruaz; A Eshkol; PC Sizonenko; Michel L Aubert
Binding kinetics of the long-acting gonadotropin-releasing hormone (GnRH) antagonist antide to rat pituitary GnRH receptors.
Endocrinology 1994;135(1):45-52.
1993: N M Gruaz; DD Pierroz; Françoise Rohner-Jeanrenaud; PC Sizonenko; Michel L Aubert
Evidence that neuropeptide Y could represent a neuroendocrine inhibitor of sexual maturation in unfavorable metabolic conditions in the rat.
Endocrinology 1993;133(4):1891-4.
1993: C Catzeflis; DD Pierroz; Françoise Rohner-Jeanrenaud; J E Rivier; PC Sizonenko; Michel L Aubert
Neuropeptide Y administered chronically into the lateral ventricle profoundly inhibits both the gonadotropic and the somatotropic axis in intact adult female rats.
Endocrinology 1993;132(1):224-34.
1990: P C Sizonenko; Y Reznik; Michel L Aubert
Urinary excretion of [D-Ser(t-Bu)6,Des-Gly10]GnRH ethylamide (buserelin) during therapy of central precocious puberty: a multicentre study.
Acta endocrinologica 1990;122(5):553-8.
1990: Yvan Arsenijevic; Michel L Aubert
[Mechanism of action of gonadoliberin in pituitary gonadotropic cells].
Annales d'endocrinologie 1990;51(2):65-71.
1989: C D Walker; R W Rivest; M J Meaney; Michel L Aubert
Differential activation of the pituitary-adrenocortical axis after stress in the rat: use of two genetically selected lines (Roman low- and high-avoidance rats) as a model.
The Journal of endocrinology 1989;123(3):477-85.
1989: C D Walker; PC Sizonenko; Michel L Aubert
Modulation of the neonatal pituitary and adrenocortical responses to stress by thyroid hormones in the rat: effects of hypothyroidism and hyperthyroidism.
Neuroendocrinology 1989;50(3):265-73.
1989: Yvan Arsenijevic; W B Wehrenberg; A Conz; A Eshkol; PC Sizonenko; Michel L Aubert
Growth hormone (GH) deprivation induced by passive immunization against rat GH-releasing factor delays sexual maturation in the male rat.
Endocrinology 1989;124(6):3050-9.
1988: F J Hemming; Michel L Aubert; P M Dubois
Differentiation of fetal rat somatotropes in vitro: effects of cortisol, 3,5,3'-triiodothyronine, and glucagon, a light microscopic and radioimmunological study.
Endocrinology 1988;123(3):1230-6.
1988: Michel L Aubert; R W Rivest; Ursula Lang; B P Winiger; PC Sizonenko
Delayed sexual maturation induced by daily melatonin administration eliminates the LH response to naloxone despite normal responsiveness to GnRH in juvenile male rats.
Neuroendocrinology 1988;48(1):72-80.
1988: M Dunand; J P Kraehenbuhl; B C Rossier; Michel L Aubert
Purification of PRL receptors from toad kidney: comparisons with rabbit mammary PRL receptors.
The American journal of physiology 1988;254(3 Pt 1):C372-82.
1988: C D Walker; Michel L Aubert
Effects of early undernutrition and handling on the adrenocortical activity of neonatal rats.
Life sciences 1988;43(24):1983-90.
1987: R W Rivest; M E Jaconi; N Gruaz; PC Sizonenko; Michel L Aubert
Short-term and long-term effects of melatonin on GnRH-stimulated gonadotropin secretion in pituitaries of sexually maturing rats.
Neuroendocrinology 1987;46(5):379-86.
1987: Yvan Arsenijevic; R W Rivest; A Eshkol; PC Sizonenko; Michel L Aubert
Plasma growth hormone (GH) response to intravenous GH-releasing factor (GRF) in adult rats: evidence for transient pituitary desensitization after GRF stimulation.
Endocrinology 1987;121(4):1487-96.
1987: Y Reznik; B P Winiger; Michel L Aubert; P C Sizonenko
Pharmacodynamics of [D-Ser (t-Bu)6,Des-Gly10]GnRH ethylamide (Buserelin) in 6 normal volunteers. Its usefulness to monitor treatment of central precocious puberty.
Acta endocrinologica 1987;115(2):235-42.
1987: M Begeot; F J Hemming; Michel L Aubert; P M Dubois
[Differentiation of pituitary cells in culture].
Annales d'endocrinologie 1987;48(5):367-77.
1986: R W Rivest; Michel L Aubert; Ursula Lang; PC Sizonenko
Puberty in the rat: modulation by melatonin and light.
Journal of neural transmission. Supplementum 1986;21():81-108.
1985: Ursula Lang; Michel L Aubert; R W Rivest; J C Vinas-Bradtke; PC Sizonenko
Inhibitory action of exogenous melatonin, 5-methoxytryptamine, and 6-hydroxymelatonin on sexual maturation of male rats: activity of 5-methoxytryptamine might be due to its conversion to melatonin.
Biology of reproduction 1985;33(3):618-28.
1985: Michel L Aubert; M Begeot; B P Winiger; G Morel; PC Sizonenko; P M Dubois
Ontogeny of hypothalamic luteinizing hormone-releasing hormone (GnRH) and pituitary GnRH receptors in fetal and neonatal rats.
Endocrinology 1985;116(4):1565-76.
1985: R W Rivest; Ursula Lang; Michel L Aubert; PC Sizonenko
Daily administration of melatonin delays rat vaginal opening and disrupts the first estrous cycles: evidence that these effects are synchronized by the onset of light.
Endocrinology 1985;116(2):779-87.
1985: PC Sizonenko; Ursula Lang; R W Rivest; Michel L Aubert
The pineal and pubertal development.
Ciba Foundation symposium 1985;117():208-30.
1985: M Dunand; Michel L Aubert; J P Kraehenbuhl; B C Rossier
Specific binding sites for ovine prolactin in three amphibian cell lines.
The American journal of physiology 1985;248(1 Pt 1):C80-7.
1984: Ursula Lang; Michel L Aubert; R W Rivest; J C Vinas-Bradtke; PC Sizonenko
Daily afternoon administration of melatonin does not irreversibly inhibit sexual maturation in the male rat.
Endocrinology 1984;115(6):2303-10.
1984: M Bégeot; F J Hemming; P M Dubois; Y Combarnous; M P Dubois; Michel L Aubert
Induction of pituitary lactotrope differentiation by luteinizing hormone alpha subunit.
Science (New York, N.Y.) 1984;226(4674):566-8.
1984: Ursula Lang; R W Rivest; L V Schlaepfer; J C Bradtke; Michel L Aubert; PC Sizonenko
Diurnal rhythm of melatonin action on sexual maturation of male rats.
Neuroendocrinology 1984;38(4):261-8.
1984: M Begeot; G Morel; R W Rivest; Michel L Aubert; M P Dubois; P M Dubois
Influence of gonadoliberin on the differentiation of rat gonadotrophs: an in vivo and in vitro study.
Neuroendocrinology 1984;38(3):217-25.
1983: B P Winiger; M A Birabeau; Ursula Lang; A M Capponi; PC Sizonenko; Michel L Aubert
Solubilization of pituitary GnRH binding sites by means of a zwitterionic detergent.
Molecular and cellular endocrinology 1983;31(1):77-91.
1983: Ursula Lang; Michel L Aubert; B S Conne; J C Bradtke; P C Sizonenko
Influence of exogenous melatonin on melatonin secretion and the neuroendocrine reproductive axis of intact male rats during sexual maturation.
Endocrinology 1983;112(5):1578-84.
1982: B S Conne; S Scaglioni; Ursula Lang; P C Sizonenko; Michel L Aubert
Pituitary receptor sites for gonadotropin-releasing hormone: effect of castration and substitutive therapy with sex steroids in the male rat.
Endocrinology 1982;110(1):70-9.
1980: Michel L Aubert; B S Conne; S Scaglioni; P C Sizonenko
[Pituitary LHRH receptor sites: quantification with a superactive analog as tracer, structure-function relationship, and change during castration in male rats (author's transl)].
Journal de physiologie 1980;76(3):207-18.