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An-Cheng Huang

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Fang-Ming Hung; Hsu-Feng Lu; Jai-Sing Yang; Yung-Liang Chen; Fu-Shin Chueh; Ming-Teng Chung; Yu-Ping Hsiao; An-Cheng Huang; Jing-Gung Chung
Triptolide induces S phase arrest via the inhibition of cyclin E and CDC25A and triggers apoptosis via caspase- and mitochondrial-dependent signaling pathways in A375.S2 human melanoma cells.
Yi-Ting Lin; Jai-Sing Yang; Chien-Chih Yu; An-Cheng Huang; Wen-Wen Huang; Chao-Lin Kuo; Yu-Hsuan Lan; Jing-Gung Chung
Induction of cell cycle arrest and apoptosis in human osteosarcoma U-2 OS cells by Solanum lyratum extracts.
Chin-Chung Lin; Jing-Pin Lin; Chi-Cheng Lu; Nou-Ying Tang; Jai-Sing Yang; Chien-Chih Yu; Jo-Hua Chiang; Ya-Ju Chuang; An-Cheng Huang; Jing-Gung Chung
Apigenin induces apoptosis through mitochondrial dysfunction in U-2 OS human osteosarcoma cells and inhibits osteosarcoma xenograft tumor growth in vivo.

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All Publications

2013: Fang-Ming Hung; Hsu-Feng Lu; Jai-Sing Yang; Yung-Liang Chen; Fu-Shin Chueh; Ming-Teng Chung; Yu-Ping Hsiao; An-Cheng Huang; Jing-Gung Chung
Triptolide induces S phase arrest via the inhibition of cyclin E and CDC25A and triggers apoptosis via caspase- and mitochondrial-dependent signaling pathways in A375.S2 human melanoma cells.
Oncology reports 2013;29(3):1053-60.
2013: Yi-Ting Lin; Jai-Sing Yang; Chien-Chih Yu; An-Cheng Huang; Wen-Wen Huang; Chao-Lin Kuo; Yu-Hsuan Lan; Jing-Gung Chung
Induction of cell cycle arrest and apoptosis in human osteosarcoma U-2 OS cells by Solanum lyratum extracts.
Nutrition and cancer 2013;65(3):469-79.
2012: Chin-Chung Lin; Jing-Pin Lin; Chi-Cheng Lu; Nou-Ying Tang; Jai-Sing Yang; Chien-Chih Yu; Jo-Hua Chiang; Ya-Ju Chuang; An-Cheng Huang; Jing-Gung Chung
Apigenin induces apoptosis through mitochondrial dysfunction in U-2 OS human osteosarcoma cells and inhibits osteosarcoma xenograft tumor growth in vivo.
Journal of agricultural and food chemistry 2012;60(45):11395-402.
2012: Chun-Shu Yu; An-Cheng Huang; Yi-Ping Huang; Kuang-Chi Lai; Meng-Wei Lin; Jai-Sing Yang; Jing-Gung Chung
Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells.
Oncology reports 2012;28(3):949-54.
2012: Fu-Shun Yu; Jo-Hua Chiang; Chang-Fang Chiu; An-Cheng Huang; Chi-Cheng Lu; Jai-Sing Yang; Chun-Shu Yu; Jing-Gung Chung
Safrole induces cell death in human tongue squamous cancer SCC-4 cells through mitochondria-dependent caspase activation cascade apoptotic signaling pathways.
Environmental toxicology 2012;27(7):433-44.
2012: S-W Ip; S-H Lan; J-C Lien; Jing-Pin Lin; Hsu-Feng Lu; Wg Wood; Jai-Sing Yang; Chang-Fang Chiu; Chin-Chin Ho; An-Cheng Huang; Hui-Ying Huang; Jing-Gung Chung
Capsaicin mediates apoptosis in human nasopharyngeal carcinoma NPC-TW 039 cells through mitochondrial depolarization and endoplasmic reticulum stress.
Human & experimental toxicology 2012;31(6):539-49.
2012: Chun-Shu Yu; Fu-Shin Chueh; Hsiung-Kwang Chung; An-Cheng Huang; Yi-Ping Huang; Chin-Chung Lin; Jai-Sing Yang; Chien-Chih Yu; Jing-Gung Chung
Safrole induces G0/G1 phase arrest via inhibition of cyclin E and provokes apoptosis through endoplasmic reticulum stress and mitochondrion-dependent pathways in human leukemia HL-60 cells.
Anticancer research 2012;32(5):1671-9.
2012: Ching-Lung Liao; Jaung-Geng Lin; Jen-Jyh Lin; Shin-Hwar Wu; Jai-Sing Yang; W Gibson Wood; An-Cheng Huang; Kuang-Chi Lai; Jing-Gung Chung
Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase B (PKB) and PKC signaling pathways.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(5):1734-40.
2012: Siu-Wan Ip; Sheng-Hui Lan; Zen-Pin Lin; Jai-Sing Yang; Mei-Due Yang; Ya-Yin Chen; Chang-Fang Chiu; Yuan-Man Hsu; An-Cheng Huang; Hui-Ying Huang; Jing-Gung Chung
Capsaicin induces apoptosis in SCC-4 human tongue cancer cells through mitochondria-dependent and -independent pathways.
Environmental toxicology 2012;27(6):332-41.
2012: Yu-Ping Hsiao; An-Cheng Huang; Hui-Ying Huang; Chi-Cheng Lu; Nou-Ying Tang; Jen-Hung Yang; Jai-Sing Yang; Chien-Chih Yu; Chun-Shu Yu; Jo-Hua Chiang; Jing-Gung Chung
Triggering apoptotic death of human malignant melanoma a375.s2 cells by bufalin: involvement of caspase cascade-dependent and independent mitochondrial signaling pathways.
Evidence-based complementary and alternative medicine : eCAM 2012;2012():591241.
2011: Chang-Lin Wu; Jai-Sing Yang; Su-Tze Chou; Te-Chun Hsia; An-Cheng Huang; Yang-Ching Ko; Ching-Lung Liao; Hsu-Feng Lu; Chia-Yu Ma; Jing-Gung Chung
Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2011;29(8):1199-209.
2011: Chin-Chung Lin; Jing-Pin Lin; Chi-Cheng Lu; Nou-Ying Tang; Jai-Sing Yang; Shu-Chun Hsu; An-Cheng Huang; Chao-Lin Kuo; Mau-Hva Lee; Jo-Hua Chiang; Fu-Shin Chueh; Jing-Gung Chung
Extract of Hedyotis diffusa Willd influences murine leukemia WEHI-3 cells in vivo as well as promoting T- and B-cell proliferation in leukemic mice.
In vivo (Athens, Greece) 2011;25(4):633-40.
2011: Yung-Liang Chen; Hsu-Feng Lu; Fang-Ming Hung; An-Cheng Huang; Shu-Ching Hsueh; Chi-Ming Liu; Jai-Sing Yang; Chien-Chih Yu; Jo-Hua Chiang; Chi-Cheng Lu; Tsan-Hung Chiu; Jing-Gung Chung
Danthron inhibits murine WEHI-3 cells in vivo, and enhances macrophage phagocytosis and natural killer cell cytotoxic activity in leukemic mice.
In vivo (Athens, Greece) 2011;25(3):393-8.
2010: Chi-Cheng Lu; Jai-Sing Yang; An-Cheng Huang; Te-Chun Hsia; Su-Tze Chou; Chao-Lin Kuo; Hsu-Feng Lu; Tsung-Han Lee; Wellington G Wood; Jing-Gung Chung
Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells.
Molecular nutrition & food research 2010;54(7):967-76.
2010: Kuang-Chi Lai; An-Cheng Huang; Shu-Chun Hsu; Chao-Lin Kuo; Jai-Sing Yang; Shin-Hwar Wu; Jing-Gung Chung
Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.
Journal of agricultural and food chemistry 2010;58(5):2935-42.
2009: Hsiu-Maan Kuo; Hung-Chieh Tsai; Ya-Ling Lin; Jai-Sing Yang; An-Cheng Huang; Mei-Due Yang; Shu-Chun Hsu; Meng-Chin Chung; W Gibson Wood; Jing-Gung Chung
Mitochondrial-dependent caspase activation pathway is involved in baicalein-induced apoptosis in human hepatoma J5 cells.
International journal of oncology 2009;35(4):717-24.
2009: An-Cheng Huang; Shu-Chun Hsu; Chao-Lin Kuo; Ching-Lung Liao; Kuang-Chi Lai; Tsung-Ping Lin; Shin-Hwar Wu; Hsu-Feng Lu; Nou-Ying Tang; Jai-Sing Yang; Jing-Gung Chung
Involvement of matrix metalloproteinases in the inhibition of cell invasion and migration through the inhibition of NF-[kappa]B by the new synthesized ethyl 2-[N-p-chlorobenzyl-(2'-methyl)]anilino-4-oxo-4,5-dihydrofuran-3-carboxylate (JOTO1007) in human cervical cancer Ca ski cells.
In vivo (Athens, Greece) 2009;23(4):613-9.
2008: Kung-Wen Lu; Ming-Li Tsai; Jung-Chou Chen; Shu-Chun Hsu; Te-Chun Hsia; Meng-Wei Lin; An-Cheng Huang; Yung-Hsien Chang; Siu-Wan Ip; Hsu-Feng Lu; Jing-Gung Chung
Gypenosides inhibited invasion and migration of human tongue cancer SCC4 cells through down-regulation of NFkappaB and matrix metalloproteinase-9.
Anticancer research 2008;28(2A):1093-9.
2007: Chin-Chung Lin; Jai-Sing Yang; Jin-Tang Chen; Shang Fan; Fu-Shun Yu; Jiun-Long Yang; Chi-Cheng Lu; Ming-Ching Kao; An-Cheng Huang; Hsu-Feng Lu; Jing-Gung Chung
Berberine induces apoptosis in human HSC-3 oral cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway.
Anticancer research 2007;27(5A):3371-8.
2007: An-Cheng Huang; Tsung-Ping Lin; Yueh-Shan Weng; Yung-Tsuan Ho; Hui-Ju Lin; Li-Jiau Huang; Sheng-Chu Kuo; Jing-Gung Chung
Ethyl 2- [N-m-chlorobenzyl- (2'-methyl)] anilino-4-oxo-4,5-dihydrofuran-3-carboxylate (JOT01006) induces apoptosis in human cervical cancer HeLa cells.
Anticancer research 2007;27(4B):2505-14.
2007: Tsung-Ping Lin; An-Cheng Huang; Hsiu-Chuan Wei; Jaung-Geng Lin; Jing-Gung Chung
Ethyl 2- [N-p-chlorobenzyl- (2'-methyl)] anilino-4-oxo-4,5-dihydrofuran-3-carboxylate (JOT01007)induces apoptosis in human cervical cancer Ca Ski cells.
In vivo (Athens, Greece) 2007;21(2):397-406.
2007: An-Cheng Huang; Jing-Gung Chung; Sheng-Chu Kuo; Hsu-Feng Lu; Tsung-Ping Lin
Synthesis and cytotoxic activity of certain 2,3,4,9-tetrahydrofuro [2,3-b] quinolin-3,4-dione and ethyl 2-(substituted aniline) -4-oxo-4,5-dihydrofuran-3-carboxylate derivatives in murine leukemia WEHI-3 cells.
In vivo (Athens, Greece) 2007;21(2):227-36.