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Christopher L-H Huang

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TOP 3
Ian N Sabir; Gareth D K Matthews; Christopher L-H Huang
Antithrombotic therapy in atrial fibrillation: aspirin is rarely the right choice.
Yanmin Zhang; Andrew A Grace; Laila Guzadhur; Christopher L-H Huang; Kamalan Jeevaratnam; James H King; Ming Lei; XiaoLei Ren; JingJing Wu; James A Fraser
Conduction slowing contributes to spontaneous ventricular arrhythmias in intrinsically active murine RyR2-P2328S hearts.
Kamalan Jeevaratnam; Ming Lei; Rebecca Rewbury; Yanmin Zhang; Andrew A Grace; Laila Guzadhur; Christopher L-H Huang
Frequency distribution analysis of activation times and regional fibrosis in murine Scn5a+/- hearts: the effects of ageing and sex.

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2013: Ian N Sabir; Gareth D K Matthews; Christopher L-H Huang
Antithrombotic therapy in atrial fibrillation: aspirin is rarely the right choice.
Postgraduate medical journal 2013;89(1052):346-51.
2013: Yanmin Zhang; Andrew A Grace; Laila Guzadhur; Christopher L-H Huang; Kamalan Jeevaratnam; James H King; Ming Lei; XiaoLei Ren; JingJing Wu; James A Fraser
Conduction slowing contributes to spontaneous ventricular arrhythmias in intrinsically active murine RyR2-P2328S hearts.
Journal of cardiovascular electrophysiology 2013;24(2):210-8.
2012: Kamalan Jeevaratnam; Ming Lei; Rebecca Rewbury; Yanmin Zhang; Andrew A Grace; Laila Guzadhur; Christopher L-H Huang
Frequency distribution analysis of activation times and regional fibrosis in murine Scn5a+/- hearts: the effects of ageing and sex.
Mechanisms of ageing and development 2012;133(9-10):591-9.
2012: Christopher L-H Huang
Andrew Fielding Huxley (1917-2012).
The Journal of physiology 2012;590(Pt 15):3415-20.
2012: Claire A Martin; Christof Schwiening; Urszula Siedlecka; Cesare M Terracciano; NL Brice; James Cartledge; Andrew A Grace; Laila Guzadhur; Kristin Kemmerich; Jason Lawrence; Christopher L-H Huang
Reduced Na(+) and higher K(+) channel expression and function contribute to right ventricular origin of arrhythmias in Scn5a+/- mice.
Open biology 2012;2(6):120072.
2012: Laila Guzadhur; Rudy M Duehmke; Andrew A Grace; Kamalan Jeevaratnam; Wenhui Jiang; Ming Lei; Sarah M Pearcey; Christopher L-H Huang
The age-dependence of atrial arrhythmogenicity in Scn5a+/- murine hearts reflects alterations in action potential propagation and recovery.
Clinical and experimental pharmacology & physiology 2012;39(6):518-27.
2012: Gareth D K Matthews; Andrew Grace; Laila Guzadhur; Christopher L-H Huang
Nonlinearity between action potential alternans and restitution, which both predict ventricular arrhythmic properties in Scn5a+/- and wild-type murine hearts.
Journal of applied physiology (Bethesda, Md. : 1985) 2012;112(11):1847-63.
2012: Claire A Martin; Gareth D K Matthews; Christopher L-H Huang
Sudden cardiac death and inherited channelopathy: the basic electrophysiology of the myocyte and myocardium in ion channel disease.
Heart (British Cardiac Society) 2012;98(7):536-43.
2012: Jingjing Wu; Henggui Zhang; Xinzhao Zhang; Yanmin Zhang; Longxian Cheng; James A Fraser; Andrew A Grace; Christopher L-H Huang; Wim J Lammers; Ming Lei
Altered sinoatrial node function and intra-atrial conduction in murine gain-of-function Scn5a+/ΔKPQ hearts suggest an overlap syndrome.
American journal of physiology. Heart and circulatory physiology 2012;302(7):H1510-23.
2012: Gary Tse; Andrew A Grace; Sandeep S Hothi; Christopher L-H Huang
Ventricular arrhythmogenesis following slowed conduction in heptanol-treated, Langendorff-perfused mouse hearts.
The journal of physiological sciences : JPS 2012;62(2):79-92.
2012: Christopher L-H Huang; Lily Lei; Gareth D K Matthews; Yanmin Zhang; Ming Lei
Pathophysiological Mechanisms of Sino-Atrial Dysfunction and Ventricular Conduction Disease Associated with SCN5A Deficiency: Insights from Mouse Models.
Frontiers in physiology 2012;3():234.
2011: Gareth D K Matthews; Li Sun; Christopher L-H Huang; Mone Zaidi
Translational musculoskeletal science: is sarcopenia the next clinical target after osteoporosis?
Annals of the New York Academy of Sciences 2011;1237():95-105.
2011: Christopher L-H Huang; Thomas H Pedersen; James A Fraser
Reciprocal dihydropyridine and ryanodine receptor interactions in skeletal muscle activation.
Journal of muscle research and cell motility 2011;32(3):171-202.
2011: Claire A Martin; Andrew A Grace; Christopher L-H Huang
Refractory dispersion promotes conduction disturbance and arrhythmias in a Scn5a (+/-) mouse model.
Pflügers Archiv : European journal of physiology 2011;462(4):495-504.
2011: Iman S Gurung; Michael Baker; Mark Campbell; Andrew A Grace; Adrienn Kis; Christopher J Lelliott; Ian McFarlane; Gema Medina-Gomez; Sudeshna Guha Neogi; Matej Oresic; Sergio Rodriguez-Cuenca; Vidya Velagapudi; Antonio Vidal-Puig; Christopher L-H Huang
Deletion of the metabolic transcriptional coactivator PGC1β induces cardiac arrhythmia.
Cardiovascular research 2011;92(1):29-38.
2011: James A Fraser; Christopher L-H Huang; Thomas H Pedersen
Relationships between resting conductances, excitability, and t-system ionic homeostasis in skeletal muscle.
The Journal of general physiology 2011;138(1):95-116.
2011: Xiaojin Hao; Christopher L-H Huang; Dimitrios Konstantinou; Mark Boyett; Laura Davies; Halina Dobrzynski; Andrew Grace; Mahesh Nirmalan; Xin Wang; Fei Yin; Henggui Zhang; Xinzhao Zhang; Yanmin Zhang; Ming Lei
TGF-β1-mediated fibrosis and ion channel remodeling are key mechanisms in producing the sinus node dysfunction associated with SCN5A deficiency and aging.
Circulation. Arrhythmia and electrophysiology 2011;4(3):397-406.
2011: Harry C Blair; Peter A Friedman; Christopher L-H Huang; Lisa J Robinson; Paul H Schlesinger; Li Sun; Mone Zaidi
Calcium and bone disease.
BioFactors (Oxford, England) 2011;37(3):159-67.
2011: Claire A Martin; Laila Guzadhur; Andrew A Grace; Ming Lei; Christopher L-H Huang
Mapping of reentrant spontaneous polymorphic ventricular tachycardia in a Scn5a+/- mouse model.
American journal of physiology. Heart and circulatory physiology 2011;300(5):H1853-62.
2011: Yanmin Zhang; James A Fraser; Kamalan Jeevaratnam; Xiaojin Hao; Sandeep S Hothi; Andrew A Grace; Ming Lei; Christopher L-H Huang
Acute atrial arrhythmogenicity and altered Ca(2+) homeostasis in murine RyR2-P2328S hearts.
Cardiovascular research 2011;89(4):794-804.
2011: Claire A Martin; Andrew A Grace; Christopher L-H Huang
Spatial and temporal heterogeneities are localized to the right ventricular outflow tract in a heterozygotic Scn5a mouse model.
American journal of physiology. Heart and circulatory physiology 2011;300(2):H605-16.
2011: Kamalan Jeevaratnam; Sui Poh Tee; Yanmin Zhang; Rebecca Rewbury; Laila Guzadhur; Rudolf Duehmke; Andrew A Grace; Ming Lei; Christopher L-H Huang
Delayed conduction and its implications in murine Scn5a(+/-) hearts: independent and interacting effects of genotype, age, and sex.
Pflügers Archiv : European journal of physiology 2011;461(1):29-44.
2010: Yana Dautova; Yanmin Zhang; Andrew A Grace; Christopher L-H Huang
Atrial arrhythmogenic properties in wild-type and Scn5a+/- murine hearts.
Experimental physiology 2010;95(10):994-1007.
2010: Claire A Martin; Yanmin Zhang; Andrew A Grace; Christopher L-H Huang
Increased right ventricular repolarization gradients promote arrhythmogenesis in a murine model of Brugada syndrome.
Journal of cardiovascular electrophysiology 2010;21(10):1153-9.
2010: Claire A Martin; Yanmin Zhang; Andrew A Grace; Christopher L-H Huang
In vivo studies of Scn5a+/- mice modeling Brugada syndrome demonstrate both conduction and repolarization abnormalities.
Journal of electrocardiology 2010;43(5):433-9.
2010: Laila Guzadhur; Sarah M Pearcey; Rudolf M Duehmke; Kamalan Jeevaratnam; Anja F Hohmann; Yanmin Zhang; Andrew A Grace; Ming Lei; Christopher L-H Huang
Atrial arrhythmogenicity in aged Scn5a+/DeltaKPQ mice modeling long QT type 3 syndrome and its relationship to Na+ channel expression and cardiac conduction.
Pflügers Archiv : European journal of physiology 2010;460(3):593-601.
2010: Parvez Hakim; Rosemary Thresher; Andrew A Grace; Christopher L-H Huang
Effects of flecainide and quinidine on action potential and ventricular arrhythmogenic properties in Scn3b knockout mice.
Clinical and experimental pharmacology & physiology 2010;37(8):782-9.
2010: Asli Kalin; Juliet Usher-Smith; Victoria J Jones; Christopher L-H Huang; Ian N Sabir
Cardiac arrhythmia: a simple conceptual framework.
Trends in cardiovascular medicine 2010;20(3):103-7.
2010: Lisa J Robinson; Harry C Blair; John B Barnett; Mone Zaidi; Christopher L-H Huang
Regulation of bone turnover by calcium-regulated calcium channels.
Annals of the New York Academy of Sciences 2010;1192():351-7.
2010: Ian N Sabir; Nan Ma; Victoria J Jones; Catharine Goddard; Yanmin Zhang; Asli Kalin; Andrew A Grace; Christopher L-H Huang
Alternans in genetically modified langendorff-perfused murine hearts modeling catecholaminergic polymorphic ventricular tachycardia.
Frontiers in physiology 2010;1():126.
2010: Anne-Laure Leoni; Bruno Gavillet; Jean-Sébastien Rougier; Céline Marionneau; Vincent Probst; Solena Le Scouarnec; Jean-Jacques Schott; Sophie Demolombe; Patrick Bruneval; Christopher L-H Huang; William H Colledge; Andrew A Grace; Hervé Le Marec; Arthur A Wilde; Peter J Mohler; Denis Escande; Hugues Abriel; Flavien Charpentier
Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model.
PloS one 2010;5(2):e9298.
2010: Michael Pazianas; Juliet Compston; Christopher L-H Huang
Atrial fibrillation and bisphosphonate therapy.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(1):2-10.
2009: Aliza Imam; Jameel Iqbal; Harry C Blair; Terry F Davies; Christopher L-H Huang; Alberta Zallone; Mone Zaidi; Li Sun
Role of the pituitary-bone axis in skeletal pathophysiology.
Current opinion in endocrinology, diabetes, and obesity 2009;16(6):423-9.
2009: Iman S Gurung; Asli Kalin; Andrew A Grace; Christopher L-H Huang
Activation of purinergic receptors by ATP induces ventricular tachycardia by membrane depolarization and modifications of Ca2+ homeostasis.
Journal of molecular and cellular cardiology 2009;47(5):622-33.
2009: Man Liu; Shamarendra Sanyal; Ge Gao; Iman S Gurung; Xiaodong Zhu; Georgia Gaconnet; Laurie J Kerchner; Lijuan L Shang; Christopher L-H Huang; Andrew Grace; Barry London; Samuel C Dudley
Cardiac Na+ current regulation by pyridine nucleotides.
Circulation research 2009;105(8):737-45.
2009: Yanmin Zhang; Christof J Schwiening; Matthew J Killeen; Yanhui Zhang; Aiqun Ma; Ming Lei; Andrew A Grace; Christopher L-H Huang
Pharmacological changes in cellular Ca2+ homeostasis parallel initiation of atrial arrhythmogenesis in murine Langendorff-perfused hearts.
Clinical and experimental pharmacology & physiology 2009;36(10):969-80.
2009: Sandeep S Hothi; Glyn Thomas; Matthew Killeen; Andrew A Grace; Christopher L-H Huang
Empirical correlation of triggered activity and spatial and temporal re-entrant substrates with arrhythmogenicity in a murine model for Jervell and Lange-Nielsen syndrome.
Pflügers Archiv : European journal of physiology 2009;458(5):819-35.
2009: Yana Dautova; Yanmin Zhang; Ian N Sabir; Andrew A Grace; Christopher L-H Huang
Atrial arrhythmogenesis in wild-type and Scn5a+/delta murine hearts modelling LQT3 syndrome.
Pflügers Archiv : European journal of physiology 2009;458(3):443-57.
2009: Juliet A Usher-Smith; Christopher L-H Huang; James A Fraser
Control of cell volume in skeletal muscle.
Biological reviews of the Cambridge Philosophical Society 2009;84(1):143-59.
2009: Nina S Ghais; Yanmin Zhang; Andrew A Grace; Christopher L-H Huang
Arrhythmogenic actions of the Ca2+ channel agonist FPL-64716 in Langendorff-perfused murine hearts.
Experimental physiology 2009;94(2):240-54.
2008: Harry C Blair; Mone Zaidi; Christopher L-H Huang; Li Sun
The developmental basis of skeletal cell differentiation and the molecular basis of major skeletal defects.
Biological reviews of the Cambridge Philosophical Society 2008;83(4):401-15.
2008: Ruiming Shi; Yanmin Zhang; Chun Yang; Chen Huang; Xihui Zhou; Hua Qiang; Andrew A Grace; Christopher L-H Huang; Aiqun Ma
The cardiac sodium channel mutation delQKP 1507-1509 is associated with the expanding phenotypic spectrum of LQT3, conduction disorder, dilated cardiomyopathy, and high incidence of youth sudden death.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2008;10(11):1329-35.
2008: Sandeep S Hothi; Iman S Gurung; Jennifer C Heathcote; Yanmin Zhang; Stephen W Booth; Jeremy N Skepper; Andrew A Grace; Christopher L-H Huang
Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart.
Pflügers Archiv : European journal of physiology 2008;457(2):253-70.
2008: Ian N Sabir; Juliet A Usher-Smith; Christopher L-H Huang; Andrew A Grace
Risk stratification for sudden cardiac death.
Progress in biophysics and molecular biology 2008;98(2-3):340-6.
2008: Nina S Ghais; Yanmin Zhang; Bina Mistry; Andrew A Grace; Christopher L-H Huang
Anti-arrhythmic effects of cyclopiazonic acid in Langendorff-perfused murine hearts.
Progress in biophysics and molecular biology 2008;98(2-3):281-8.
2008: Sandeep S Hothi; Stephen W Booth; Ian N Sabir; Matthew Killeen; Fergus Simpson; Yanmin Zhang; Andrew A Grace; Christopher L-H Huang
Arrhythmogenic substrate and its modification by nicorandil in a murine model of long QT type 3 syndrome.
Progress in biophysics and molecular biology 2008;98(2-3):267-80.
2008: Parvez Hakim; Iman S Gurung; Thomas H Pedersen; Rosemary Thresher; Nicola Brice; Jason Lawrence; Andrew A Grace; Christopher L-H Huang
Scn3b knockout mice exhibit abnormal ventricular electrophysiological properties.
Progress in biophysics and molecular biology 2008;98(2-3):251-66.
2008: Ming Lei; Andrew A Grace; Christopher L-H Huang; Denis Noble
Cardiac arrhythmogenesis is a major clinical problem.
Progress in biophysics and molecular biology 2008;98(2-3):119.
2008: Ian N Sabir; Matthew Killeen; Andrew A Grace; Christopher L-H Huang
Ventricular arrhythmogenesis: insights from murine models.
Progress in biophysics and molecular biology 2008;98(2-3):208-18.
2008: Matthew J Killeen; Ian N Sabir; Andrew A Grace; Christopher L-H Huang
Dispersions of repolarization and ventricular arrhythmogenesis: lessons from animal models.
Progress in biophysics and molecular biology 2008;98(2-3):219-29.
2008: Ming Lei; Christopher L-H Huang; Yanmin Zhang
Genetic Na+ channelopathies and sinus node dysfunction.
Progress in biophysics and molecular biology 2008;98(2-3):171-8.
2008: Jianhua Huo; Yanmin Zhang; Na Huang; Ping Liu; Chen Huang; Xueyan Guo; Wenhui Jiang; Nan Zhou; Andrew Grace; Christopher L-H Huang; Aiqun Ma
The G604S-hERG mutation alters the biophysical properties and exerts a dominant-negative effect on expression of hERG channels in HEK293 cells.
Pflügers Archiv : European journal of physiology 2008;456(5):917-28.
2008: Richard C Saumarez; Mariusz Pytkowski; Maciej Sterlinski; John Bourke; Jonathan R Clague; Stuart M Cobbe; Derek T Connelly; Michael J Griffith; Pascal P McKeown; Karen McLeod; John M Morgan; Nicolas Sadoul; Lidia Chojnowska; Christopher L-H Huang; Andrew A Grace
Paced ventricular electrogram fractionation predicts sudden cardiac death in hypertrophic cardiomyopathy.
European heart journal 2008;29(13):1653-61.
2008: Arpan R Mehta; Christopher L-H Huang; Jeremy N Skepper; James A Fraser
Extracellular charge adsorption influences intracellular electrochemical homeostasis in amphibian skeletal muscle.
Biophysical journal 2008;94(11):4549-60.
2008: Justin M Smith; Michael F James; James A Fraser; Christopher L-H Huang
Translational imaging studies of cortical spreading depression in experimental models for migraine aura.
Expert review of neurotherapeutics 2008;8(5):759-68.
2008: Ian N Sabir; Lucia M Li; Victoria J Jones; Catharine Goddard; Andrew A Grace; Christopher L-H Huang
Criteria for arrhythmogenicity in genetically-modified Langendorff-perfused murine hearts modelling the congenital long QT syndrome type 3 and the Brugada syndrome.
Pflügers Archiv : European journal of physiology 2008;455(4):637-51.
2008: Ian N Sabir; Lucia M Li; Andrew A Grace; Christopher L-H Huang
Restitution analysis of alternans and its relationship to arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts.
Pflügers Archiv : European journal of physiology 2008;455(4):653-66.
2007: Christopher L-H Huang; Li Sun; James A Fraser; Andrew A Grace; Mone Zaidi
Similarities and contrasts in ryanodine receptor localization and function in osteoclasts and striated muscle cells.
Annals of the New York Academy of Sciences 2007;1116():255-70.
2007: Li Sun; Ling Ling Zhu; Neeha Zaidi; Guozhe Yang; Baljit S Moonga; Etsuko Abe; Jameel Iqbal; Solomon Epstein; Harry C Blair; Christopher L-H Huang; Mone Zaidi
Cellular and molecular consequences of calcineurin A alpha gene deletion.
Annals of the New York Academy of Sciences 2007;1116():216-26.
2007: Ian N Sabir; James A Fraser; Thomas R Cass; Andrew A Grace; Christopher L-H Huang
A quantitative analysis of the effect of cycle length on arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts.
Pflügers Archiv : European journal of physiology 2007;454(6):925-36.
2007: Yanmin Zhang; Nan Zhou; Wenhui Jiang; Jun Peng; Hongmei Wan; Chen Huang; Zenghui Xie; Christopher L-H Huang; Andrew A Grace; Aiqun Ma
A missense mutation (G604S) in the S5/pore region of HERG causes long QT syndrome in a Chinese family with a high incidence of sudden unexpected death.
European journal of pediatrics 2007;166(9):927-33.
2007: James A Fraser; Christopher L-H Huang
Quantitative techniques for steady-state calculation and dynamic integrated modelling of membrane potential and intracellular ion concentrations.
Progress in biophysics and molecular biology 2007;94(3):336-72.
2007: Ming Lei; Henggui Zhang; Andrew A Grace; Christopher L-H Huang
SCN5A and sinoatrial node pacemaker function.
Cardiovascular research 2007;74(3):356-65.
2007: Ian N Sabir; Matthew Killeen; Catharine Goddard; Glyn Thomas; Simon Gray; Andrew A Grace; Christopher L-H Huang
Transient alterations in transmural repolarization gradients and arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts.
The Journal of physiology 2007;581(Pt 1):277-89.
2007: Kate S Stokoe; Richard Balasubramaniam; Catharine Goddard; William H Colledge; Andrew A Grace; Christopher L-H Huang
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/- murine hearts modelling the Brugada syndrome.
The Journal of physiology 2007;581(Pt 1):255-75.
2007: Ian N Sabir; James A Fraser; Matthew Killeen; Andrew A Grace; Christopher L-H Huang
The contribution of refractoriness to arrhythmic substrate in hypokalemic Langendorff-perfused murine hearts.
Pflügers Archiv : European journal of physiology 2007;454(2):209-22.
2007: Zhongbo Chen; Sandeep S Hothi; Wei Xu; Christopher L-H Huang
Conduction velocities in amphibian skeletal muscle fibres exposed to hyperosmotic extracellular solutions.
Journal of muscle research and cell motility 2007;28(4-5):195-202.
2007: Juliet A Usher-Smith; James A Fraser; Christopher L-H Huang; Jeremy N Skepper
Alterations in triad ultrastructure following repetitive stimulation and intracellular changes associated with exercise in amphibian skeletal muscle.
Journal of muscle research and cell motility 2007;28(1):19-28.
2007: Glyn Thomas; Iman S Gurung; Matthew Killeen; Parvez Hakim; Catharine Goddard; Martyn P Mahaut-Smith; William H Colledge; Andrew A Grace; Christopher L-H Huang
Effects of L-type Ca2+ channel antagonism on ventricular arrhythmogenesis in murine hearts containing a modification in the Scn5a gene modelling human long QT syndrome 3.
The Journal of physiology 2007;578(Pt 1):85-97.
2007: Glyn Thomas; Matthew Killeen; Iman S Gurung; Parvez Hakim; Richard Balasubramaniam; Catharine Goddard; Andrew A Grace; Christopher L-H Huang
Mechanisms of ventricular arrhythmogenesis in mice following targeted disruption of KCNE1 modelling long QT syndrome 5.
The Journal of physiology 2007;578(Pt 1):99-114.
2007: Kate S Stokoe; Glyn Thomas; Catharine Goddard; William H Colledge; Andrew A Grace; Christopher L-H Huang
Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3.
The Journal of physiology 2007;578(Pt 1):69-84.
2006: Juliet A Usher-Smith; Wei Xu; James A Fraser; Christopher L-H Huang
Alterations in calcium homeostasis reduce membrane excitability in amphibian skeletal muscle.
Pflügers Archiv : European journal of physiology 2006;453(2):211-21.
2006: Justin M Smith; Daniel P Bradley; Michael F James; Christopher L-H Huang
Physiological studies of cortical spreading depression.
Biological reviews of the Cambridge Philosophical Society 2006;81(4):457-81.
2006: Richard C Saumarez; Mariusz Pytkowski; Maciej Sterlinski; Richard N W Hauer; Richard Derksen; Martin D Lowe; Hannah Szwed; Christopher L-H Huang; David E Ward; A John Camm; Andrew A Grace
Delayed paced ventricular activation in the long QT syndrome is associated with ventricular fibrillation.
Heart rhythm : the official journal of the Heart Rhythm Society 2006;3(7):771-8.
2006: Jamie I Vandenberg; Anthony Varghese; Yu Lu; Jane A Bursill; Martyn P Mahaut-Smith; Christopher L-H Huang
Temperature dependence of human ether-a-go-go-related gene K+ currents.
American journal of physiology. Cell physiology 2006;291(1):C165-75.
2006: Juliet A Usher-Smith; James A Fraser; Peter S J Bailey; Julian L Griffin; Christopher L-H Huang
The influence of intracellular lactate and H+ on cell volume in amphibian skeletal muscle.
The Journal of physiology 2006;573(Pt 3):799-818.
2006: Juliet A Usher-Smith; Jeremy N Skepper; James A Fraser; Christopher L-H Huang
Effect of repetitive stimulation on cell volume and its relationship to membrane potential in amphibian skeletal muscle.
Pflügers Archiv : European journal of physiology 2006;452(2):231-9.
2006: James A Fraser; Kai Yuen Wong; Juliet A Usher-Smith; Christopher L-H Huang
Membrane potentials in Rana temporaria muscle fibres in strongly hypertonic solutions.
Journal of muscle research and cell motility 2006;27(8):591-606.
2005: Catherine E Head; Richard Balasubramaniam; Glyn Thomas; Catharine Goddard; Ming Lei; William H Colledge; Andrew A Grace; Christopher L-H Huang
Paced electrogram fractionation analysis of arrhythmogenic tendency in DeltaKPQ Scn5a mice.
Journal of cardiovascular electrophysiology 2005;16(12):1329-40.
2005: Bhashkar Mukherjee; Mark Preece; Gavin C Houston; Nikos G Papadakis; T Adrian Carpenter; Laurance D Hall; Christopher L-H Huang
Mapping of the cerebral response to acetazolamide using graded asymmetric spin echo EPI.
Magnetic resonance imaging 2005;23(9):907-20.
2005: Richard G Wise; Ahmad I M Al-Shafei; T Adrian Carpenter; Laurance D Hall; Christopher L-H Huang
Simultaneous measurement of blood and myocardial velocity in the rat heart by phase contrast MRI using sparse q-space sampling.
Journal of magnetic resonance imaging : JMRI 2005;22(5):614-27.
2005: Richard Balasubramaniam; Sangeeta Chawla; Andrew A Grace; Christopher L-H Huang
Caffeine-induced arrhythmias in murine hearts parallel changes in cellular Ca(2+) homeostasis.
American journal of physiology. Heart and circulatory physiology 2005;289(4):H1584-93.
2005: Toon A B van Veen; Mera Stein; Anne Royer; Khai Le Quang; Flavien Charpentier; William H Colledge; Christopher L-H Huang; Ronald Wilders; Andrew A Grace; Denis Escande; Jacques M T de Bakker; Harold V M van Rijen
Impaired impulse propagation in Scn5a-knockout mice: combined contribution of excitability, connexin expression, and tissue architecture in relation to aging.
Circulation 2005;112(13):1927-35.
2005: Ming Lei; Catharine Goddard; Jie Liu; Anne-Laure Léoni; Anne Royer; Simon S-M Fung; Guosheng Xiao; Aiqun Ma; Henggui Zhang; Flavien Charpentier; Jamie I Vandenberg; William H Colledge; Andrew A Grace; Christopher L-H Huang
Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a.
The Journal of physiology 2005;567(Pt 2):387-400.
2005: James A Fraser; Catherine E J Rang; Juliet A Usher-Smith; Christopher L-H Huang
Slow volume transients in amphibian skeletal muscle fibres studied in hypotonic solutions.
The Journal of physiology 2005;564(Pt 1):51-63.
2005: James A Fraser; Claire E Middlebrook; Juliet A Usher-Smith; Christof J Schwiening; Christopher L-H Huang
The effect of intracellular acidification on the relationship between cell volume and membrane potential in amphibian skeletal muscle.
The Journal of physiology 2005;563(Pt 3):745-64.
2004: Richard Balasubramaniam; Sangeeta Chawla; Lauren Mackenzie; Christof J Schwiening; Andrew A Grace; Christopher L-H Huang
Nifedipine and diltiazem suppress ventricular arrhythmogenesis and calcium release in mouse hearts.
Pflügers Archiv : European journal of physiology 2004;449(2):150-8.
2004: James A Fraser; Christopher L-H Huang
A quantitative analysis of cell volume and resting potential determination and regulation in excitable cells.
The Journal of physiology 2004;559(Pt 2):459-78.
2004: Angela M Inzerillo; Mone Zaidi; Christopher L-H Huang
Calcitonin: physiological actions and clinical applications.
Journal of pediatric endocrinology & metabolism : JPEM 2004;17(7):931-40.
2004: Sangeeta Chawla; Christopher L-H Huang
FPL-64176 alters both charge movement and Ca2+ release properties in amphibian muscle fibres.
Pflügers Archiv : European journal of physiology 2004;447(6):922-7.
2004: Emily A Ferenczi; James A Fraser; Sangeeta Chawla; Jeremy N Skepper; Christof J Schwiening; Christopher L-H Huang
Membrane potential stabilization in amphibian skeletal muscle fibres in hypertonic solutions.
The Journal of physiology 2004;555(Pt 2):423-38.
2004: Mone Zaidi; Baljit S Moonga; Christopher L-H Huang
Calcium sensing and cell signaling processes in the local regulation of osteoclastic bone resorption.
Biological reviews of the Cambridge Philosophical Society 2004;79(1):79-100.
2004: Jann Yee Chin; Hugh R Matthews; James A Fraser; Jeremy N Skepper; Sangeeta Chawla; Christopher L-H Huang
Detubulation experiments localise delayed rectifier currents to the surface membrane of amphibian skeletal muscle fibres.
Journal of muscle research and cell motility 2004;25(4-5):389-95.
2004: Diana X-L Chin; James A Fraser; Juliet A Usher-Smith; Jeremy N Skepper; Christopher L-H Huang
Detubulation abolishes membrane potential stabilization in amphibian skeletal muscle.
Journal of muscle research and cell motility 2004;25(4-5):379-87.
2003: Chaiyapoj Netsiri; Daniel P Bradley; Tsunehiro Takeda; Martin I Smith; Nikos G Papadakis; Laurance D Hall; Andrew A Parsons; Michael F James; Christopher L-H Huang
A delayed class of BOLD waveforms associated with spreading depression in the feline cerebral cortex can be detected and characterised using independent component analysis (ICA).
Magnetic resonance imaging 2003;21(9):1097-110.
2003: Richard Balasubramaniam; Andrew A Grace; Richard C Saumarez; Jamie I Vandenberg; Christopher L-H Huang
Electrogram prolongation and nifedipine-suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1.
The Journal of physiology 2003;552(Pt 2):535-46.
2003: David S Yu; Eiichiro Sonoda; Shunichi Takeda; Christopher L-H Huang; Luca Pellegrini; Tom L Blundell; Ashok R Venkitaraman
Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2.
Molecular cell 2003;12(4):1029-41.
2003: Yu Lu; Martyn P Mahaut-Smith; Christopher L-H Huang; Jamie I Vandenberg
Mutant MiRP1 subunits modulate HERG K+ channel gating: a mechanism for pro-arrhythmia in long QT syndrome type 6.
The Journal of physiology 2003;551(Pt 1):253-62.
2003: Richard C Saumarez; Lidia Chojnowska; Richard Derksen; Mariusz Pytkowski; Maciej Sterlinski; Christopher L-H Huang; Nicolas Sadoul; Richard N W Hauer; Witold Ruzyłło; Andrew A Grace
Sudden death in noncoronary heart disease is associated with delayed paced ventricular activation.
Circulation 2003;107(20):2595-600.
2003: Mone Zaidi; Harry C Blair; Baljit S Moonga; Etsuko Abe; Christopher L-H Huang
Osteoclastogenesis, bone resorption, and osteoclast-based therapeutics.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(4):599-609.
2003: Sangeeta Chawla; Peter Vanhoutte; Fiona J L Arnold; Christopher L-H Huang; Hilmar Bading
Neuronal activity-dependent nucleocytoplasmic shuttling of HDAC4 and HDAC5.
Journal of neurochemistry 2003;85(1):151-9.
2003: Li Sun; Jameel Iqbal; Svetlana Dolgilevich; Tony Yuen; Xue-Bin Wu; Baljit S Moonga; Olugbenga A Adebanjo; Peter J R Bevis; Frances Lund; Christopher L-H Huang; Harry C Blair; Etsuko Abe; Mone Zaidi
Disordered osteoclast formation and function in a CD38 (ADP-ribosyl cyclase)-deficient mouse establishes an essential role for CD38 in bone resorption.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(3):369-75.
2003: Li Sun; Baljit S Moonga; Min Lu; Neeha Zaidi; Jameel Iqbal; Harry C Blair; Solomon Epstein; Etsuko Abe; Bruce R Troen; Christopher L-H Huang; Mone Zaidi
Molecular cloning, expression, and function of osteoclastic calcineurin Aalpha.
American journal of physiology. Renal physiology 2003;284(3):F575-83.
2003: Claire A Martin; Nayia Petousi; Sangeeta Chawla; Austin R Hockaday; Antony J Burgess; James A Fraser; Christopher L-H Huang; Jeremy N Skepper
The effect of extracellular tonicity on the anatomy of triad complexes in amphibian skeletal muscle.
Journal of muscle research and cell motility 2003;24(7):407-15.
2002: Daniel P Bradley; Justin M Smith; Martin I Smith; Kurt H-J Bockhorst; Nikos G Papadakis; Laurance D Hall; Andrew A Parsons; Michael F James; Christopher L-H Huang
Cortical spreading depression in the feline brain following sustained and transient stimuli studied using diffusion-weighted imaging.
The Journal of physiology 2002;544(Pt 1):39-56.
2002: Angela M Inzerillo; Mone Zaidi; Christopher L-H Huang
Calcitonin: the other thyroid hormone.
Thyroid : official journal of the American Thyroid Association 2002;12(9):791-8.
2002: Baljit S Moonga; Sun Li; Jameel Iqbal; Robert Davidson; Vijai S Shankar; Peter J R Bevis; Angela M Inzerillo; Etsuko Abe; Christopher L-H Huang; Mone Zaidi
Ca(2+) influx through the osteoclastic plasma membrane ryanodine receptor.
American journal of physiology. Renal physiology 2002;282(5):F921-32.
2002: G Alex Papadatos; Polly M R Wallerstein; Catherine E G Head; Rosemary Ratcliff; Peter A Brady; Klaus Benndorf; Richard C Saumarez; Ann E O Trezise; Christopher L-H Huang; Jamie I Vandenberg; William H Colledge; Andrew A Grace
Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6210-5.
2002: Sangeeta Chawla; Jeremy N Skepper; Christopher L-H Huang
Differential effects of sarcoplasmic reticular Ca(2+)-ATPase inhibition on charge movements and calcium transients in intact amphibian skeletal muscle fibres.
The Journal of physiology 2002;539(Pt 3):869-82.
2002: Li Sun; Olugbenga A Adebanjo; Anatoliy Koval; Hindupur K Anandatheerthavarada; Jameel Iqbal; Xing Y Wu; Baljit S Moonga; Xue-Bin Wu; Gopa Biswas; Peter J R Bevis; Masayoshi Kumegawa; Solomon Epstein; Christopher L-H Huang; Narayan G Avadhani; Etsuko Abe; Mone Zaidi
A novel mechanism for coupling cellular intermediary metabolism to cytosolic Ca2+ signaling via CD38/ADP-ribosyl cyclase, a putative intracellular NAD+ sensor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(3):302-14.
2002: Ahmad I M Al-Shafei; Richard G Wise; GA Gresham; T Adrian Carpenter; Laurance D Hall; Christopher L-H Huang
Magnetic resonance imaging analysis of cardiac cycle events in diabetic rats: the effect of angiotensin-converting enzyme inhibition.
The Journal of physiology 2002;538(Pt 2):555-72.
2002: Ahmad I M Al-Shafei; Richard G Wise; GA Gresham; G Bronns; T Adrian Carpenter; Laurance D Hall; Christopher L-H Huang
Non-invasive magnetic resonance imaging assessment of myocardial changes and the effects of angiotensin-converting enzyme inhibition in diabetic rats.
The Journal of physiology 2002;538(Pt 2):541-53.
2002: Sarah J Cooper; Sangeeta Chawla; James A Fraser; Jeremy N Skepper; Christopher L-H Huang
Separation of detubulation and vacuolation phenomena in amphibian skeletal muscle.
Journal of muscle research and cell motility 2002;23(4):327-33.
2002: Sangeeta Chawla; Jeremy N Skepper; James F Fraser; Christopher L-H Huang
Osmotic processes in vacuolation and detubulation of skeletal muscle.
Cell biology international 2002;26(10):905-10.
2001: Y Lu; Martyn P Mahaut-Smith; Anthony Varghese; Christopher L-H Huang; Paul R Kemp; Jamie I Vandenberg
Effects of premature stimulation on HERG K(+) channels.
The Journal of physiology 2001;537(Pt 3):843-51.
2001: Ahmad I M Al-Shafei; Richard G Wise; A A Grace; T Adrian Carpenter; Laurance D Hall; Christopher L-H Huang
MRI analysis of right ventricular function in normal and spontaneously hypertensive rats.
Magnetic resonance imaging 2001;19(10):1297-304.
2001: Daniel P Bradley; Martin I Smith; Chaiyapoj Netsiri; Justin M Smith; Kurt H-J Bockhorst; Laurance D Hall; Christopher L-H Huang; Ronald A Leslie; Andrew A Parsons; Michael F James
Diffusion-weighted MRI used to detect in vivo modulation of cortical spreading depression: comparison of sumatriptan and tonabersat.
Experimental neurology 2001;172(2):342-53.
2001: M Preece; Bhashkar Mukherjee; Christopher L-H Huang; Laurance D Hall; Ronald A Leslie; Michael F James
Detection of pharmacologically mediated changes in cerebral activity by functional magnetic resonance imaging: the effects of sulpiride in the brain of the anaesthetised rat.
Brain research 2001;916(1-2):107-14.
2001: Sangeeta Chawla; Jeremy N Skepper; Austin R Hockaday; Christopher L-H Huang
Calcium waves induced by hypertonic solutions in intact frog skeletal muscle fibres.
The Journal of physiology 2001;536(Pt 2):351-9.
2001: Gavin C Houston; Nikos G Papadakis; T Adrian Carpenter; Laurance D Hall; Bhashkar Mukherjee; Michael F James; Christopher L-H Huang
Mapping of brain activation in response to pharmacological agents using fMRI in the rat.
Magnetic resonance imaging 2001;19(7):905-19.
2001: S M Sheikh; Jeremy N Skepper; Sangeeta Chawla; Jamie I Vandenberg; Suzy Elneil; Christopher L-H Huang
Normal conduction of surface action potentials in detubulated amphibian skeletal muscle fibres.
The Journal of physiology 2001;535(Pt 2):579-90.
2001: Baljit S Moonga; R Davidson; Li Sun; Olugbenga A Adebanjo; J Moser; M Abedin; Neeha Zaidi; Christopher L-H Huang; Mone Zaidi
Identification and characterization of a sodium/calcium exchanger, NCX-1, in osteoclasts and its role in bone resorption.
Biochemical and biophysical research communications 2001;283(4):770-5.
2001: Justin M Smith; Michael F James; Kurt H-J Bockhorst; Martin I Smith; Daniel P Bradley; Nikos G Papadakis; T Adrian Carpenter; Andrew A Parsons; Ronald A Leslie; Laurance D Hall; Christopher L-H Huang
Investigation of feline brain anatomy for the detection of cortical spreading depression with magnetic resonance imaging.
Journal of anatomy 2001;198(Pt 5):537-54.
2001: Christopher L-H Huang
Charge movements in intact amphibian skeletal muscle fibres in the presence of cardiac glycosides.
The Journal of physiology 2001;532(Pt 2):509-23.
2000: Gavin C Houston; Nikos G Papadakis; T Adrian Carpenter; Laurance D Hall; Bhashkar Mukherjee; Michael F James; Christopher L-H Huang
Mapping of the cerebral response to hypoxia measured using graded asymmetric spin echo EPI.
Magnetic resonance imaging 2000;18(9):1043-54.
2000: Kurt H-J Bockhorst; Justin M Smith; Martin I Smith; Daniel P Bradley; Gavin C Houston; T Adrian Carpenter; Laurance D Hall; Nikos G Papadakis; Andrew A Parsons; Christopher L-H Huang; Michael F James
A quantitative analysis of cortical spreading depression events in the feline brain characterized with diffusion-weighted MRI.
Journal of magnetic resonance imaging : JMRI 2000;12(5):722-33.
2000: Nikos G Papadakis; Kay M Martin; John D Pickard; Laurance D Hall; T Adrian Carpenter; Christopher L-H Huang
Gradient preemphasis calibration in diffusion-weighted echo-planar imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2000;44(4):616-24.
2000: Nikos G Papadakis; C D Murrills; Laurance D Hall; Christopher L-H Huang; T Adrian Carpenter
Minimal gradient encoding for robust estimation of diffusion anisotropy.
Magnetic resonance imaging 2000;18(6):671-9.
2000: V L Keevil; Christopher L-H Huang; P L Chau; Rana A Sayeed; Jamie I Vandenberg
The effect of heptanol on the electrical and contractile function of the isolated, perfused rabbit heart.
Pflügers Archiv : European journal of physiology 2000;440(2):275-82.
2000: K N Khan; Jeremy N Skepper; Austin R Hockaday; A J Burgess; Christopher L-H Huang
Loop diuretics inhibit detubulation and vacuolation in amphibian muscle fibres exposed to osmotic shock.
Journal of muscle research and cell motility 2000;21(1):79-90.
1999: Olugbenga A Adebanjo; Hindupur K Anandatheerthavarada; Anatoliy Koval; Baljit S Moonga; Gopa Biswas; Li Sun; BR Sodam; Peter J R Bevis; Christopher L-H Huang; Solomon Epstein; FA Lai; Narayan G Avadhani; Mone Zaidi
A new function for CD38/ADP-ribosyl cyclase in nuclear Ca2+ homeostasis.
Nature cell biology 1999;1(7):409-14.
1999: Richard G Wise; Christopher L-H Huang; Ahmad I M Al-Shafei; T Adrian Carpenter; Laurance D Hall
Geometrical models of left ventricular contraction from MRI of the normal and spontaneously hypertensive rat heart.
Physics in medicine and biology 1999;44(10):2657-76.
1999: Michael F James; Martin I Smith; Kurt H-J Bockhorst; Laurance D Hall; Gavin C Houston; Nikos G Papadakis; Justin M Smith; A J Williams; D Xing; Andrew A Parsons; Christopher L-H Huang; T Adrian Carpenter
Cortical spreading depression in the gyrencephalic feline brain studied by magnetic resonance imaging.
The Journal of physiology 1999;519 Pt 2():415-25.
1999: Kay M Martin; Nikos G Papadakis; Christopher L-H Huang; Laurance D Hall; T Adrian Carpenter
The reduction of the sorting bias in the eigenvalues of the diffusion tensor.
Magnetic resonance imaging 1999;17(6):893-901.
1999: Nikos G Papadakis; D Xing; Gavin C Houston; Justin M Smith; Martin I Smith; Michael F James; Andrew A Parsons; Christopher L-H Huang; Laurance D Hall; T Adrian Carpenter
A study of rotationally invariant and symmetric indices of diffusion anisotropy.
Magnetic resonance imaging 1999;17(6):881-92.
1999: Guy B Williams; B J Fisher; Christopher L-H Huang; T Adrian Carpenter; Laurance D Hall
Design of biplanar gradient coils for magnetic resonance imaging of the human torso and limbs.
Magnetic resonance imaging 1999;17(5):739-54.
1999: S Nik-Zainal; Jeremy N Skepper; Austin R Hockaday; Christopher L-H Huang
Cardiac glycosides inhibit detubulation in amphibian skeletal muscle fibres exposed to osmotic shock.
Journal of muscle research and cell motility 1999;20(1):45-53.
1998: Richard G Wise; Christopher L-H Huang; GA Gresham; Ahmad I M Al-Shafei; T Adrian Carpenter; Laurance D Hall
Magnetic resonance imaging analysis of left ventricular function in normal and spontaneously hypertensive rats.
The Journal of physiology 1998;513 ( Pt 3)():873-87.
1998: Christopher L-H Huang
The influence of caffeine on intramembrane charge movements in intact frog striated muscle.
The Journal of physiology 1998;512 ( Pt 3)():707-21.
1998: James A Fraser; Jeremy N Skepper; Austin R Hockaday; Christopher L-H Huang
The tubular vacuolation process in amphibian skeletal muscle.
Journal of muscle research and cell motility 1998;19(6):613-29.
1998: Christopher L-H Huang
The influence of perchlorate ions on complex charging transients in amphibian striated muscle.
The Journal of physiology 1998;506 ( Pt 3)():699-714.
1997: Ferdia Gallagher; Christopher L-H Huang
Osmotic 'detubulation' in frog muscle arises from a reversible vacuolation process.
Journal of muscle research and cell motility 1997;18(3):305-21.
1997: D Xing; Nikos G Papadakis; Christopher L-H Huang; V M Lee; T Adrian Carpenter; Laurance D Hall
Optimised diffusion-weighting for measurement of apparent diffusion coefficient (ADC) in human brain.
Magnetic resonance imaging 1997;15(7):771-84.
1996: Christopher L-H Huang
Kinetic isoforms of intramembrane charge in intact amphibian striated muscle.
The Journal of general physiology 1996;107(4):515-34.