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Kuo-Sen Huang

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Procedures

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Physiology

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Publications

TOP 3
Yimin Qian; Tsutomu Sato; Qing Xiang; Weiya Yun; David R Bolin; Karin Conde-Knape; Paul Gillespie; Stuart Hayden; Kuo-Sen Huang; Andrée R Olivier; Xiaolei Zhang
Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators.
David Fry; Takeo Harada; Kuo-Sen Huang; Peter Mohr; Klaus Müller; Sung-Sau So; Martin Stahl; Binh T Vu; Paola Di Lello; Harald Mauser
Design of libraries targeting protein-protein interfaces.
Bradford Graves; Kuo-Sen Huang; Cheryl Janson; Allen Lovey; Christine Lukacs; Thelma Thompson; Christian Tovar; Dayanand Deo; Paola Di Lello; David Fry; Lin Gao; Colin Garvie; Jutta Wanner; Mingxuan Xia; Lyubomir T Vassilev
Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization.

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All Publications

2013: Yimin Qian; Tsutomu Sato; Qing Xiang; Weiya Yun; David R Bolin; Karin Conde-Knape; Paul Gillespie; Stuart Hayden; Kuo-Sen Huang; Andrée R Olivier; Xiaolei Zhang
Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators.
Bioorganic & medicinal chemistry letters 2013;23(10):2936-40.
2013: David Fry; Takeo Harada; Kuo-Sen Huang; Peter Mohr; Klaus Müller; Sung-Sau So; Martin Stahl; Binh T Vu; Paola Di Lello; Harald Mauser
Design of libraries targeting protein-protein interfaces.
ChemMedChem 2013;8(5):726-32.
2012: Bradford Graves; Kuo-Sen Huang; Cheryl Janson; Allen Lovey; Christine Lukacs; Thelma Thompson; Christian Tovar; Dayanand Deo; Paola Di Lello; David Fry; Lin Gao; Colin Garvie; Jutta Wanner; Mingxuan Xia; Lyubomir T Vassilev
Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(29):11788-93.
2012: Tobias Koschubs; Dirk Kostrewa; Martin Lanzendörfer; Kathryn Packman; Stefan Ries; Alvin Stern; Johannes Auer; Patrick Cramer; Stefan Dengl; Harald Dürr; Guy Georges; Ueli Gubler; Silke Hansen; Christiane Hartl; Kuo-Sen Huang; Stefan Jennewein; Klaus Kaluza; Ulrich Kohnert; Olaf Mundigl
Allosteric antibody inhibition of human hepsin protease.
The Biochemical journal 2012;442(3):483-94.
2011: Charles A Wartchow; Xiaolei Zhang; Shirley Li; David Mark; Frank Podlaski; Karen Rowan; Kuo-Sen Huang
Biosensor-based small molecule fragment screening with biolayer interferometry.
Journal of computer-aided molecular design 2011;25(7):669-76.
2011: Yimin Qian; Stanley J Wertheimer; Mushtaq Ahmad; Adrian Wai-Hing Cheung; Fariborz Firooznia; Matthew M Hamilton; Stuart Hayden; Shiming Li; Nicholas Marcopulos; Lee McDermott; Jenny Tan; Weiya Yun; Liang Guo; Anjula Pamidimukkala; Yingsi Chen; Kuo-Sen Huang; Gwendolyn B Ramsey; Toni Whittard; Karin Conde-Knape; Rebecca Taub; Cristina M Rondinone; Jefferson W Tilley; David Bolin
Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes.
Journal of medicinal chemistry 2011;54(7):2433-46.
2008: Sherif Daouti; Wen-hui Li; Hong Qian; Kuo-Sen Huang; Janna Holmgren; Wayne Levin; Linda Reik; Debra Lucas McGady; Paul Gillespie; Agostino Perrotta; Hongjin Bian; John Reidhaar-Olson; Sarah A Bliss; Andree R Olivier; Joseph A Sergi; David Fry; Waleed Danho; Steve Ritland; Nader Fotouhi; David Heimbrook; Huifeng Niu
A selective phosphatase of regenerating liver phosphatase inhibitor suppresses tumor cell anchorage-independent growth by a novel mechanism involving p130Cas cleavage.
Cancer research 2008;68(4):1162-9.
2006: Kuo-Sen Huang; David Mark; Frank Ulrich Gandenberger
High-throughput measurements of biochemical responses using the plate::vision multimode 96 minilens array reader.
Methods in enzymology 2006;414():589-600.
2005: Kuo-Sen Huang; Lyubomir T Vassilev
High-throughput screening for inhibitors of the Cks1-Skp2 interaction.
Methods in enzymology 2005;399():717-28.
2004: Kuo-Sen Huang; Janna Holmgren; Linda Reik; Debra Lucas-McGady; John Roberts; Chao-Min Liu; Wayne Levin
High-throughput methods for measuring heparanase activity and screening potential antimetastatic and anti-inflammatory agents.
Analytical biochemistry 2004;333(2):389-98.
2003: Kui Xu; Charles Belunis; Wei Chu; David Weber; Frank Podlaski; Kuo-Sen Huang; Steven I Reed; Lyubomir T Vassilev
Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase.
The Biochemical journal 2003;371(Pt 3):957-64.
2003: Elizabeth A Gaudet; Kuo-Sen Huang; Yan Zhang; Wei Huang; David Mark; J Richard Sportsman
A homogeneous fluorescence polarization assay adaptable for a range of protein serine/threonine and tyrosine kinases.
Journal of biomolecular screening 2003;8(2):164-75.