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Leaf Huang

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Co-Publications
Name
22
Li, Song
19
Liu, Feng
9
Tyagi, Pradeep
9
Hung, Mien-Chie
8
wang, liang
7
Falo, Louis
7
Xia, Weiya
7
Li, Shyh-Dar
7
Gao, Xiang
6
Bambara, Robert
6
Chancellor, Michael
6
Chesnoy, Sophie
6
Yoshimura, Naoki
6
Pitt, Bruce
5
Tan, Yadi

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Publications

TOP 3
Li Shyh-Dar; Huang Leaf
Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer.
Tseng Yu-Cheng; Mozumdar Subho; Huang Leaf
Lipid-based systemic delivery of siRNA.
Chen Yunching; Sen Joyeeta; Bathula Surendar Reddy; Yang Qi; Fittipaldi Raffaella; Huang Leaf
Novel cationic lipid that delivers siRNA and enhances therapeutic effect in lung cancer cells.

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All Publications

2009: Li Shyh-Dar; Huang Leaf
Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer.
Biochimica et biophysica acta 2009;1788(10):2259-66.
2009: Tseng Yu-Cheng; Mozumdar Subho; Huang Leaf
Lipid-based systemic delivery of siRNA.
Advanced drug delivery reviews 2009;61(9):721-31.
2009: Chen Yunching; Sen Joyeeta; Bathula Surendar Reddy; Yang Qi; Fittipaldi Raffaella; Huang Leaf
Novel cationic lipid that delivers siRNA and enhances therapeutic effect in lung cancer cells.
Molecular pharmaceutics 2009;6(3):696-705.
2009: Gao Kun; Huang Leaf
Nonviral methods for siRNA delivery.
Molecular pharmaceutics 2009;6(3):651-8.
2009: Yan Weili; Huang Leaf
The effects of salt on the physicochemical properties and immunogenicity of protein based vaccine formulated in cationic liposome.
International journal of pharmaceutics 2009;368(1-2):56-62.
2008: Chen Yunching; Huang Leaf
Tumor-targeted delivery of siRNA by non-viral vector: safe and effective cancer therapy.
Expert opinion on drug delivery 2008;5(12):1301-11.
2008: Li Shyh-Dar; Huang Leaf
Targeted delivery of siRNA by nonviral vectors: lessons learned from recent advances.
Current opinion in investigational drugs (London, England : 2000) 2008;9(12):1317-23.
2008: Chono Sumio; Li Shyh-Dar; Conwell Christine C; Huang Leaf
An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor.
Journal of controlled release : official journal of the Controlled Release Society 2008;131(1):64-9.
2008: Yan Weili; Chen Weihsu; Huang Leaf
Reactive oxygen species play a central role in the activity of cationic liposome based cancer vaccine.
Journal of controlled release : official journal of the Controlled Release Society 2008;130(1):22-8.
2008: Li Shyh-Dar; Huang Leaf
Pharmacokinetics and biodistribution of nanoparticles.
Molecular pharmaceutics 2008;5(4):496-504.
2008: Li Shyh-Dar; Chono Sumio; Huang Leaf
Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(5):942-6.
2008: Chen Weihsu; Huang Leaf
Induction of cytotoxic T-lymphocytes and antitumor activity by a liposomal lipopeptide vaccine.
Molecular pharmaceutics 2008;5(3):464-71.
2008: Chen Weihsu; Yan Weili; Huang Leaf
A simple but effective cancer vaccine consisting of an antigen and a cationic lipid.
Cancer immunology, immunotherapy : CII 2008;57(4):517-30.
2008: Toyokawa Hideyoshi; Nakao Atsunori; Bailey Robert J; Nalesnik Michael A; Kaizu Takashi; Lemoine Jerome L; Ikeda Atsushi; Tomiyama Koji; Papworth Glenn D; Huang Leaf; Demetris Anthony J; Starzl Thomas E; Murase Noriko
Relative contribution of direct and indirect allorecognition in developing tolerance after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2008;14(3):346-57.
2008: Tyagi Pradeep; Chancellor Michael; Yoshimura Naoki; Huang Leaf
Activity of different phospholipids in attenuating hyperactivity in bladder irritation.
BJU international 2008;101(5):627-32.
2008: Li Shyh-Dar; Chono Sumio; Huang Leaf
Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles.
Journal of controlled release : official journal of the Controlled Release Society 2008;126(1):77-84.
2008: Conwell Christine C; Liu Feng; Huang Leaf
Several serum proteins significantly decrease inflammatory response to lipid-based non-viral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(2):370-7.
2008: Li Shyh-Dar; Chen Yun-Ching; Hackett Michael J; Huang Leaf
Tumor-targeted delivery of siRNA by self-assembled nanoparticles.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(1):163-9.
2007: Li Shyh-Dar; Huang Leaf
Non-viral is superior to viral gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2007;123(3):181-3.
2007: Liu Feng; Shollenberger Lisa M; Conwell Christine C; Yuan Xing; Huang Leaf
Mechanism of naked DNA clearance after intravenous injection.
The journal of gene medicine 2007;9(7):613-9.
2007: Yan Weili; Chen Weihsu; Huang Leaf
Mechanism of adjuvant activity of cationic liposome: phosphorylation of a MAP kinase, ERK and induction of chemokines.
Molecular immunology 2007;44(15):3672-81.
2007: Lee Pui Yan; Cobain Erin; Huard Johnny; Huang Leaf
Thermosensitive hydrogel PEG-PLGA-PEG enhances engraftment of muscle-derived stem cells and promotes healing in diabetic wound.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(6):1189-94.
2007: Liu Feng; Conwell Christine C; Yuan Xing; Shollenberger Lisa M; Huang Leaf
Novel nonviral vectors target cellular signaling pathways: regulated gene expression and reduced toxicity.
The Journal of pharmacology and experimental therapeutics 2007;321(2):777-83.
2007: Olton Dana; Li Jinhua; Wilson Mary E; Rogers Todd; Close John; Huang Leaf; Kumta Prashant N; Sfeir Charles
Nanostructured calcium phosphates (NanoCaPs) for non-viral gene delivery: influence of the synthesis parameters on transfection efficiency.
Biomaterials 2007;28(6):1267-79.
2006: Tyagi Pradeep; Tyagi Shachi; Kaufman Jonathan; Huang Leaf; de Miguel Fernando
Local drug delivery to bladder using technology innovations.
The Urologic clinics of North America 2006;33(4):519-30, x.
2006: Li Shyh-Dar; Huang Leaf
Surface-modified LPD nanoparticles for tumor targeting.
Annals of the New York Academy of Sciences 2006;1082():1-8.
2006: Vangasseri Dileep P; Cui Zhengrong; Chen Weihsu; Hokey David A; Falo Louis D; Huang Leaf
Immunostimulation of dendritic cells by cationic liposomes.
Molecular membrane biology 2006;23(5):385-95.
2006: Li Shyh-Dar; Huang Leaf
Targeted delivery of antisense oligodeoxynucleotide and small interference RNA into lung cancer cells.
Molecular pharmaceutics 2006;3(5):579-88.
2006: Li S-D; Huang L
Gene therapy progress and prospects: non-viral gene therapy by systemic delivery.
Gene therapy 2006;13(18):1313-9.
2006: Tyagi Pradeep; Banerjee Rajkumar; Basu Soumitra; Yoshimura Naoki; Chancellor Michael; Huang Leaf
Intravesical antisense therapy for cystitis using TAT-peptide nucleic acid conjugates.
Molecular pharmaceutics 2006;3(4):398-406.
2006: Tyagi Pradeep; Wu Pao-Chu; Chancellor Michael; Yoshimura Naoki; Huang Leaf
Recent advances in intravesical drug/gene delivery.
Molecular pharmaceutics 2006;3(4):369-79.
2006: Liu Feng; Heston Steve; Shollenberger Lisa M; Sun Bin; Mickle Marlin; Lovell Michael; Huang Leaf
Mechanism of in vivo DNA transport into cells by electroporation: electrophoresis across the plasma membrane may not be involved.
The journal of gene medicine 2006;8(3):353-61.
2006: Mu Ying; Zhang Jinnan; Zhang Shimin; Zhou Hong-Hao; Toma David; Ren Songrong; Huang Leaf; Yaramus Maria; Baum Andrew; Venkataramanan Raman; Xie Wen
Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats.
The Journal of pharmacology and experimental therapeutics 2006;316(3):1369-77.
2006: Zhang Jing-Shi; Liu Feng; Conwell Christine C; Tan Yadi; Huang Leaf
Mechanistic studies of sequential injection of cationic liposome and plasmid DNA.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(2):429-37.
2005: Cui Zhengrong; Huang Leaf
Liposome-polycation-DNA (LPD) particle as a carrier and adjuvant for protein-based vaccines: therapeutic effect against cervical cancer.
Cancer immunology, immunotherapy : CII 2005;54(12):1180-90.
2005: Vangasseri Dileep Padinjarae; Han Su-Ji; Huang Leaf
Lipid-protamine-DNA-mediated antigen delivery.
Current drug delivery 2005;2(4):401-6.
2005: Wilson Annette; Zhou Wen; Champion Hunter C; Alber Sean; Tang Zhi-Lue; Kennel Steven; Watkins Simon; Huang Leaf; Pitt Bruce; Li Song
Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(3):510-8.
2005: Lemoine J L; Farley R; Huang L
Mechanism of efficient transfection of the nasal airway epithelium by hypotonic shock.
Gene therapy 2005;12(16):1275-82.
2005: Zhang Jing-Shi; Liu Feng; Huang Leaf
Implications of pharmacokinetic behavior of lipoplex for its inflammatory toxicity.
Advanced drug delivery reviews 2005;57(5):689-98.
2005: Cui Zhengrong; Han Su-Ji; Vangasseri Dileep Padinjarae; Huang Leaf
Immunostimulation mechanism of LPD nanoparticle as a vaccine carrier.
Molecular pharmaceutics 2005;2(1):22-8.
2005: Conwell Christine C; Huang Leaf
Recent advances in non-viral gene delivery.
Advances in genetics 2005;53():3-18.
2005: Chen Weihsu Claire; Huang Leaf
Non-viral vector as vaccine carrier.
Advances in genetics 2005;54():315-37.
2004: Banerjee Rajkumar; Tyagi Pradeep; Li Song; Huang Leaf
Anisamide-targeted stealth liposomes: a potent carrier for targeting doxorubicin to human prostate cancer cells.
International journal of cancer. Journal international du cancer 2004;112(4):693-700.
2004: Liu Feng; Shollenberger Lisa M; Huang Leaf
Non-immunostimulatory nonviral vectors.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(14):1779-81.
2004: Hyndman Laura; Lemoine Jerome L; Huang Leaf; Porteous David J; Boyd A Christopher; Nan Xinsheng
HIV-1 Tat protein transduction domain peptide facilitates gene transfer in combination with cationic liposomes.
Journal of controlled release : official journal of the Controlled Release Society 2004;99(3):435-44.
2004: Lee Pui-Yan; Chesnoy Sophie; Huang Leaf
Electroporatic delivery of TGF-beta1 gene works synergistically with electric therapy to enhance diabetic wound healing in db/db mice.
The Journal of investigative dermatology 2004;123(4):791-8.
2004: Li Zhenhua; Huang Leaf
Sustained delivery and expression of plasmid DNA based on biodegradable polyester, poly(D,L-lactide-co-4-hydroxy-L-proline).
Journal of controlled release : official journal of the Controlled Release Society 2004;98(3):437-46.
2004: Cui Zhengrong; Han Su-Ji; Huang Leaf
Coating of mannan on LPD particles containing HPV E7 peptide significantly enhances immunity against HPV-positive tumor.
Pharmaceutical research 2004;21(6):1018-25.
2004: Liang K W; Nishikawa M; Liu F; Sun B; Ye Q; Huang L
Restoration of dystrophin expression in mdx mice by intravascular injection of naked DNA containing full-length dystrophin cDNA.
Gene therapy 2004;11(11):901-8.
2004: Tyagi Pradeep; Li Zhenhua; Chancellor Michael; De Groat William C; Yoshimura Naoki; Huang Leaf
Sustained intravesical drug delivery using thermosensitive hydrogel.
Pharmaceutical research 2004;21(5):832-7.
2004: Liu Feng; Lei Jing; Vollmer Regis; Huang Leaf
Mechanism of liver gene transfer by mechanical massage.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(3):452-7.
2004: Stabile L P; Lyker J S; Huang L; Siegfried J M
Inhibition of human non-small cell lung tumors by a c-Met antisense/U6 expression plasmid strategy.
Gene therapy 2004;11(3):325-35.
2004: Tyagi Pradeep; Chancellor Michael B; Li Zhenhua; De Groat William C; Yoshimura Naoki; Fraser Matthew O; Huang Leaf
Urodynamic and immunohistochemical evaluation of intravesical capsaicin delivery using thermosensitive hydrogel and liposomes.
The Journal of urology 2004;171(1):483-9.
2003: Lee Pui-Yan; Li Zhenhua; Huang Leaf
Thermosensitive hydrogel as a Tgf-beta1 gene delivery vehicle enhances diabetic wound healing.
Pharmaceutical research 2003;20(12):1995-2000.
2003: Sturlan Sanda; Schneeberger Achim; Fang Min; Beinhauer Britta G; Lührs Petra; Kutil Raphaela; Wessner Barbara; Huang Leaf; Aasen Ansgar O; Rogy Michael A
Intraperitoneal administration of pMP6/liposome complexes inhibits the growth of co-localized colon-26 adenocarcinoma cells by inducing a tumor-specific immune response.
Anticancer research 2003;23(6C):4843-51.
2003: Li Zhenhua; Ning Wen; Wang Jumei; Choi Augustine; Lee Pui-Yan; Tyagi Pradeep; Huang Leaf
Controlled gene delivery system based on thermosensitive biodegradable hydrogel.
Pharmaceutical research 2003;20(6):884-8.
2003: Dileo John; Banerjee Rajkumar; Whitmore Mark; Nayak Jayakar V; Falo Louis D; Huang Leaf
Lipid-protamine-DNA-mediated antigen delivery to antigen-presenting cells results in enhanced anti-tumor immune responses.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(5 Pt 1):640-8.
2003: Zhang J; Wilson A; Alber S; Ma Z; Tang Z-L; Satoh E; Mazda O; Watkins S; Huang L; Pitt B; Li S
Prolonged gene expression in mouse lung endothelial cells following transfection with Epstein-Barr virus-based episomal plasmid.
Gene therapy 2003;10(9):822-6.
2003: Chesnoy Sophie; Lee Pui-Yan; Huang Leaf
Intradermal injection of transforming growth factor-beta1 gene enhances wound healing in genetically diabetic mice.
Pharmaceutical research 2003;20(3):345-50.
2003: Chuang Yao-Chi; Chancellor Michael B; Seki Satoshi; Yoshimura Naoki; Tyagi Pradeep; Huang Leaf; Lavelle John P; De Groat William C; Fraser Matthew O
Intravesical protamine sulfate and potassium chloride as a model for bladder hyperactivity.
Urology 2003;61(3):664-70.
2003: Fraser Matthew O; Chuang Yao-Chi; Tyagi Pradeep; Yokoyama Teruhiko; Yoshimura Naoki; Huang Leaf; De Groat William C; Chancellor Michael B
Intravesical liposome administration--a novel treatment for hyperactive bladder in the rat.
Urology 2003;61(3):656-63.
2003: Yuan Xing; Ma Zheng; Zhou Wen; Niidome Takuro; Alber Sean; Huang Leaf; Watkins Simon; Li Song
Lipid-mediated delivery of peptide nucleic acids to pulmonary endothelium.
Biochemical and biophysical research communications 2003;302(1):6-11.
2003: Dileo John; Miller Theodore E; Chesnoy Sophie; Huang Leaf
Gene transfer to subdermal tissues via a new gene gun design.
Human gene therapy 2003;14(1):79-87.
2003: Zhang Jing-Shi; Li Song; Huang Leaf
Cationic liposome-protamine-DNA complexes for gene delivery.
Methods in enzymology 2003;373():332-42.
2002: Tan Yadi; Zhang Jing Shi; Huang Leaf
Codelivery of NF-kappaB decoy-related oligodeoxynucleotide improves LPD-mediated systemic gene transfer.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(6):804-12.
2002: Niidome T; Huang L
Gene therapy progress and prospects: nonviral vectors.
Gene therapy 2002;9(24):1647-52.
2002: Ueno Naoto T; Bartholomeusz Chandra; Xia Weiya; Anklesaria Pervin; Bruckheimer Elizabeth M; Mebel Elise; Paul Ralph; Li Song; Yo George H; Huang Leaf; Hung Mien-Chie
Systemic gene therapy in human xenograft tumor models by liposomal delivery of the E1A gene.
Cancer research 2002;62(22):6712-6.
2002: Sturlan Sanda; Beinhauer Britta G; Oberhuber Georg; Huang Leaf; Aasen Ansgar O; Rogy Michael A
In vivo gene transfer of murine interleukin-4 inhibits colon-26-mediated cancer cachexia in mice.
Anticancer research 2002;22(5):2547-54.
2002: Ma Zheng; Zhang Junlan; Alber Sean; Dileo John; Negishi Yoichi; Stolz Donna; Watkins Simon; Huang Leaf; Pitt Bruce; Li Song
Lipid-mediated delivery of oligonucleotide to pulmonary endothelium.
American journal of respiratory cell and molecular biology 2002;27(2):151-9.
2002: Liu F; Huang L
Electric gene transfer to the liver following systemic administration of plasmid DNA.
Gene therapy 2002;9(16):1116-9.
2002: Liu Feng; Huang Leaf
Noninvasive gene delivery to the liver by mechanical massage.
Hepatology (Baltimore, Md.) 2002;35(6):1314-9.
2002: Zeng Qing; Kanter Peter M; Dhir Rajiv; Gooding William E; Huang Leaf; Grandis Jennifer Rubin
Lack of toxicity of EGFR antisense gene therapy.
Journal of experimental therapeutics & oncology 2002;2(3):174-86.
2002: Tan Yadi; Huang Leaf
Overcoming the inflammatory toxicity of cationic gene vectors.
Journal of drug targeting 2002;10(2):153-60.
2002: Liu Feng; Huang Leaf
A syringe electrode device for simultaneous injection of DNA and electrotransfer.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(3):323-8.
2002: Lui Vivian Wai Yan; He Yukai; Falo Louis; Huang Leaf
Systemic administration of naked DNA encoding interleukin 12 for the treatment of human papillomavirus DNA-positive tumor.
Human gene therapy 2002;13(2):177-85.
2002: Chesnoy Sophie; Huang Leaf
Enhanced cutaneous gene delivery following intradermal injection of naked DNA in a high ionic strength solution.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(1):57-62.
2002: Liu Feng; Huang Leaf
Development of non-viral vectors for systemic gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2002;78(1-3):259-66.
2002: Tan Yadi; Whitmore Mark; Li Song; Frederik Peter; Huang Leaf
LPD nanoparticles--novel nonviral vector for efficient gene delivery.
Methods in molecular medicine 2002;69():73-81.
2001: Whitmore M M; Li S; Falo L; Huang L
Systemic administration of LPD prepared with CpG oligonucleotides inhibits the growth of established pulmonary metastases by stimulating innate and acquired antitumor immune responses.
Cancer immunology, immunotherapy : CII 2001;50(10):503-14.
2001: Liu F; Huang L
Improving plasmid DNA-mediated liver gene transfer by prolonging its retention in the hepatic vasculature.
The journal of gene medicine 2001;3(6):569-76.
2001: Chesnoy S; Durand D; Doucet J; Stolz D B; Huang L
Improved DNA/emulsion complex stabilized by poly(ethylene glycol) conjugated phospholipid.
Pharmaceutical research 2001;18(10):1480-4.
2001: Liu F; Liang K W; Huang L
Systemic administration of naked DNA: gene transfer to skeletal muscle.
Molecular interventions 2001;1(3):168-72.
2001: Lui V W; Falo L D; Huang L
Systemic production of IL-12 by naked DNA mediated gene transfer: toxicity and attenuation of transgene expression in vivo.
The journal of gene medicine 2001;3(4):384-93.
2001: Liu F; Nishikawa M; Clemens P R; Huang L
Transfer of full-length Dmd to the diaphragm muscle of Dmd(mdx/mdx) mice through systemic administration of plasmid DNA.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(1):45-51.
2001: Hortobagyi G N; Ueno N T; Xia W; Zhang S; Wolf J K; Putnam J B; Weiden P L; Willey J S; Carey M; Branham D L; Payne J Y; Tucker S D; Bartholomeusz C; Kilbourn R G; De Jager R L; Sneige N; Katz R L; Anklesaria P; Ibrahim N K; Murray J L; Theriault R L; Valero V; Gershenson D M; Bevers M W; Huang L; Lopez-Berestein G; Hung M C
Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(14):3422-33.
2001: Nishikawa M; Huang L
Nonviral vectors in the new millennium: delivery barriers in gene transfer.
Human gene therapy 2001;12(8):861-70.
2001: Tan Y; Liu F; Li Z; Li S; Huang L
Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(5 Pt 1):673-82.
2001: Yang J; Chen S; Huang L; Michalopoulos G K; Liu Y
Sustained expression of naked plasmid DNA encoding hepatocyte growth factor in mice promotes liver and overall body growth.
Hepatology (Baltimore, Md.) 2001;33(4):848-59.
2001: Wu X; He Y; Falo L D; Hui K M; Huang L
Regression of human mammary adenocarcinoma by systemic administration of a recombinant gene encoding the hFlex-TRAIL fusion protein.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(3):368-74.
2001: Lui V W; He Y; Huang L
Specific down-regulation of HER-2/neu mediated by a chimeric U6 hammerhead ribozyme results in growth inhibition of human ovarian carcinoma.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(2):169-77.
2001: Hofman C R; Dileo J P; Li Z; Li S; Huang L
Efficient in vivo gene transfer by PCR amplified fragment with reduced inflammatory activity.
Gene therapy 2001;8(1):71-4.
2000: Endo S; Zeng Q; Burke N A; He Y; Melhem M F; Watkins S F; Lango M N; Drenning S D; Huang L; Rubin Grandis J
TGF-alpha antisense gene therapy inhibits head and neck squamous cell carcinoma growth in vivo.
Gene therapy 2000;7(22):1906-14.
2000: Rogy M A; Beinhauer B G; Reinisch W; Huang L; Pokieser P
Transfer of interleukin-4 and interleukin-10 in patients with severe inflammatory bowel disease of the rectum.
Human gene therapy 2000;11(12):1731-41.
2000: Glorioso J C; Huang L; Dunbar C; Felgner P L
Highlights from the third annual ASGT meeting. American Society of Gene Therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(2):96-100.
2000: Grandis J R; Drenning S D; Zeng Q; Watkins S C; Melhem M F; Endo S; Johnson D E; Huang L; He Y; Kim J D
Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4227-32.
2000: Liang K W; Hoffman E P; Huang L
Targeted delivery of plasmid DNA to myogenic cells via transferrin-conjugated peptide nucleic acid.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(3):236-43.
2000: He Y; Pimenov A A; Nayak J V; Plowey J; Falo L D; Huang L
Intravenous injection of naked DNA encoding secreted flt3 ligand dramatically increases the number of dendritic cells and natural killer cells in vivo.
Human gene therapy 2000;11(4):547-54.
2000: Li S; Tan Y; Viroonchatapan E; Pitt B R; Huang L
Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody.
American journal of physiology. Lung cellular and molecular physiology 2000;278(3):L504-11.
2000: Huang L; Li X; El-Hodiri H M; Dayal S; Wikramanayake A H; Klein W H
Involvement of Tcf/Lef in establishing cell types along the animal-vegetal axis of sea urchins.
Development genes and evolution 2000;210(2):73-81.
2000: Li S; Huang L
Nonviral gene therapy: promises and challenges.
Gene therapy 2000;7(1):31-4.
2000: Chesnoy S; Huang L
Structure and function of lipid-DNA complexes for gene delivery.
Annual review of biophysics and biomolecular structure 2000;29():27-47.
1999: Whitmore M; Li S; Huang L
LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth.
Gene therapy 1999;6(11):1867-75.
1999: Brisson M; Tseng W C; Almonte C; Watkins S; Huang L
Subcellular trafficking of the cytoplasmic expression system.
Human gene therapy 1999;10(16):2601-13.
1999: Tan Y; Li S; Pitt B R; Huang L
The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo.
Human gene therapy 1999;10(13):2153-61.
1999: Savva M; Duda E; Huang L
A genetically modified recombinant tumor necrosis factor-alpha conjugated to the distal terminals of liposomal surface grafted polyethyleneglycol chains.
International journal of pharmaceutics 1999;184(1):45-51.
1999: Li S; Wu S P; Whitmore M; Loeffert E J; Wang L; Watkins S C; Pitt B R; Huang L
Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors.
The American journal of physiology 1999;276(5 Pt 1):L796-804.
1999: Brisson M; Huang L
Liposomes: conquering the nuclear barrier.
Current opinion in molecular therapeutics 1999;1(2):140-6.
1999: Li S; Tseng W C; Stolz D B; Wu S P; Watkins S C; Huang L
Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection.
Gene therapy 1999;6(4):585-94.
1999: Ueno N T; Xia W; Tucker S D; Zhang S; Lopez-Berestein G; Huang L; Hung M C
Issues in the development of gene therapy: preclinical experiments in E1A gene delivery.
Oncology reports 1999;6(2):257-62.
1999: Brisson M; He Y; Li S; Yang J P; Huang L
A novel T7 RNA polymerase autogene for efficient cytoplasmic expression of target genes.
Gene therapy 1999;6(2):263-70.
1998: Xing X; Zhang S; Chang J Y; Tucker S D; Chen H; Huang L; Hung M C
Safety study and characterization of E1A-liposome complex gene-delivery protocol in an ovarian cancer model.
Gene therapy 1998;5(11):1538-44.
1998: He Y K; Lui V W; Baar J; Wang L; Shurin M; Almonte C; Watkins S C; Huang L
Potentiation of E7 antisense RNA-induced antitumor immunity by co-delivery of IL-12 gene in HPV16 DNA-positive mouse tumor.
Gene therapy 1998;5(11):1462-71.
1998: Li S; Deshmukh H M; Huang L
Folate-mediated targeting of antisense oligodeoxynucleotides to ovarian cancer cells.
Pharmaceutical research 1998;15(10):1540-5.
1998: Wikramanayake A H; Huang L; Klein W H
beta-Catenin is essential for patterning the maternally specified animal-vegetal axis in the sea urchin embryo.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9343-8.
1998: Li S; Rizzo M A; Bhattacharya S; Huang L
Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery.
Gene therapy 1998;5(7):930-7.
1998: He Y; Zeng Q; Drenning S D; Melhem M F; Tweardy D J; Huang L; Grandis J R
Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter.
Journal of the National Cancer Institute 1998;90(14):1080-7.
1998: Yang J P; Huang L
Time-dependent maturation of cationic liposome-DNA complex for serum resistance.
Gene therapy 1998;5(3):380-7.
1997: Hara T; Tan Y; Huang L
In vivo gene delivery to the liver using reconstituted chylomicron remnants as a novel nonviral vector.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14547-52.
1997: Sorgi F L; Bhattacharya S; Huang L
Protamine sulfate enhances lipid-mediated gene transfer.
Gene therapy 1997;4(9):961-8.
1997: Yang J P; Huang L
Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA.
Gene therapy 1997;4(9):950-60.
1997: Li S; Huang L
In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes.
Gene therapy 1997;4(9):891-900.
1997: He Y; Huang L
Growth inhibition of human papillomavirus 16 DNA-positive mouse tumor by antisense RNA transcribed from U6 promoter.
Cancer research 1997;57(18):3993-9.
1997: Feero W G; Li S; Rosenblatt J D; Sirianni N; Morgan J E; Partridge T A; Huang L; Hoffman E P
Selection and use of ligands for receptor-mediated gene delivery to myogenic cells.
Gene therapy 1997;4(7):664-74.
1997: Liu F; Qi H; Huang L; Liu D
Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration.
Gene therapy 1997;4(6):517-23.
1997: Li S; Brisson M; He Y; Huang L
Delivery of a PCR amplified DNA fragment into cells: a model for using synthetic genes for gene therapy.
Gene therapy 1997;4(5):449-54.
1997: Xing X; Liu V; Xia W; Stephens L C; Huang L; Lopez-Berestein G; Hung M C
Safety studies of the intraperitoneal injection of E1A--liposome complex in mice.
Gene therapy 1997;4(3):238-43.
1997: Chang J Y; Xia W; Shao R; Sorgi F; Hortobagyi G N; Huang L; Hung M C
The tumor suppression activity of E1A in HER-2/neu-overexpressing breast cancer.
Oncogene 1997;14(5):561-8.
1996: Liu F; Yang J; Huang L; Liu D
New cationic lipid formulations for gene transfer.
Pharmaceutical research 1996;13(12):1856-60.
1996: Liu F; Yang J; Huang L; Liu D
Effect of non-ionic surfactants on the formation of DNA/emulsion complexes and emulsion-mediated gene transfer.
Pharmaceutical research 1996;13(11):1642-6.
1996: Bedu-Addo F K; Huang L
Effect of matrix lipid chain length on liposomes containing cholesterol and ganglioside GM1: implications in drug delivery.
Journal of pharmaceutical sciences 1996;85(7):714-9.
1996: Son K; Huang L
Factors influencing the drug sensitization of human tumor cells for in situ lipofection.
Gene therapy 1996;3(7):630-4.
1996: Huang L; Rumbaugh J A; Murante R S; Lin R J; Rust L; Bambara R A
Role of calf RTH-1 nuclease in removal of 5'-ribonucleotides during Okazaki fragment processing.
Biochemistry 1996;35(28):9266-77.
1996: Yang J P; Huang L
Direct gene transfer to mouse melanoma by intratumor injection of free DNA.
Gene therapy 1996;3(6):542-8.
1996: Xing X; Matin A; Yu D; Xia W; Sorgi F; Huang L; Hung M C
Mutant SV40 large T antigen as a therapeutic agent for HER-2/neu-overexpressing ovarian cancer.
Cancer gene therapy 1996;3(3):168-74.
1996: Lee R J; Huang L
Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer.
The Journal of biological chemistry 1996;271(14):8481-7.
1996: Huang L; Son K; Gao X; Hages D; Yang Y Y; Holden S A; Teicher B; Kirkwood J; Lazo J S
Efficient lipofection with cisplatin-resistant human tumor cells.
Cancer gene therapy 1996;3(2):107-12.
1996: Gao X; Huang L
Potentiation of cationic liposome-mediated gene delivery by polycations.
Biochemistry 1996;35(3):1027-36.
1996: Mori A; Wu S P; Han I; Khokhar A R; Perez-Soler R; Huang L
In vivo antitumor activity of cis-bis-neodecanoato-trans-R,R-1, 2-diaminocyclohexane platinum(II) formulated in long-circulating liposomes.
Cancer chemotherapy and pharmacology 1996;37(5):435-44.
1995: Gao X; Huang L
Cationic liposome-mediated gene transfer.
Gene therapy 1995;2(10):710-22.
1995: Huang L; Farhood H; Serbina N; Teepe A G; Barsoum J
Endosomolytic activity of cationic liposomes enhances the delivery of human immunodeficiency virus-1 trans-activator protein (TAT) to mammalian cells.
Biochemical and biophysical research communications 1995;217(3):761-8.
1995: Yu D; Matin A; Xia W; Sorgi F; Huang L; Hung M C
Liposome-mediated in vivo E1A gene transfer suppressed dissemination of ovarian cancer cells that overexpress HER-2/neu.
Oncogene 1995;11(7):1383-8.
1995: Hung M C; Matin A; Zhang Y; Xing X; Sorgi F; Huang L; Yu D
HER-2/neu-targeting gene therapy--a review.
Gene 1995;159(1):65-71.
1995: Farhood H; Serbina N; Huang L
The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer.
Biochimica et biophysica acta 1995;1235(2):289-95.
1995: Hofland H; Huang L
Inhibition of human ovarian carcinoma cell proliferation by liposome-plasmid DNA complex.
Biochemical and biophysical research communications 1995;207(2):492-6.
1995: Farhood H; Gao X; Barsoum J; Huang L
Codelivery to mammalian cells of a transcriptional factor with cis-acting element using cationic liposomes.
Analytical biochemistry 1995;225(1):89-93.
1995: Li S; Khokhar A R; Perez-Soler R; Huang L
Improved antitumor activity of cis-Bis-neodecanoato-trans-R,R-1,2- diaminocyclohexaneplatinum (II) entrapped in long-circulating liposomes.
Oncology research 1995;7(12):611-7.
1995: Mori A; Kennel S J; van Borssum Waalkes M; Scherphof G L; Huang L
Characterization of organ-specific immunoliposomes for delivery of 3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine in a mouse lung-metastasis model.
Cancer chemotherapy and pharmacology 1995;35(6):447-56.
1995: Bambara R A; Huang L
Reconstitution of mammalian DNA replication.
Progress in nucleic acid research and molecular biology 1995;51():93-122.
1994: Son K; Huang L
Exposure of human ovarian carcinoma to cisplatin transiently sensitizes the tumor cells for liposome-mediated gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12669-72.
1994: Turchi J J; Huang L; Murante R S; Kim Y; Bambara R A
Enzymatic completion of mammalian lagging-strand DNA replication.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9803-7.
1994: Huang L; Kim Y; Turchi J J; Bambara R A
Structure-specific cleavage of the RNA primer from Okazaki fragments by calf thymus RNase HI.
The Journal of biological chemistry 1994;269(41):25922-7.
1994: Gao X; Jaffurs D; Robbins P D; Huang L
A sustained, cytoplasmic transgene expression system delivered by cationic liposomes.
Biochemical and biophysical research communications 1994;200(3):1201-6.
1994: Farhood H; Gao X; Son K; Yang Y Y; Lazo J S; Huang L; Barsoum J; Bottega R; Epand R M
Cationic liposomes for direct gene transfer in therapy of cancer and other diseases.
Annals of the New York Academy of Sciences 1994;716():23-34; discussion 34-5.
1994: Litzinger D C; Buiting A M; van Rooijen N; Huang L
Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes.
Biochimica et biophysica acta 1994;1190(1):99-107.
1994: Murante R S; Huang L; Turchi J J; Bambara R A
The calf 5'- to 3'-exonuclease is also an endonuclease with both activities dependent on primers annealed upstream of the point of cleavage.
The Journal of biological chemistry 1994;269(2):1191-6.
1993: Huang L; Turchi J J; Wahl A F; Bambara R A
Activity of calf thymus DNA helicase E on cis-diamminedichloroplatinum (II)-damaged DNA.
The Journal of biological chemistry 1993;268(35):26731-7.
1993: Gao X; Huang L
Cytoplasmic expression of a reporter gene by co-delivery of T7 RNA polymerase and T7 promoter sequence with cationic liposomes.
Nucleic acids research 1993;21(12):2867-72.
1993: Mori A; Kennel S J; Huang L
Immunotargeting of liposomes containing lipophilic antitumor prodrugs.
Pharmaceutical research 1993;10(4):507-14.
1992: Farhood H; Bottega R; Epand R M; Huang L
Effect of cationic cholesterol derivatives on gene transfer and protein kinase C activity.
Biochimica et biophysica acta 1992;1111(2):239-46.

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