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Shaohua Huang

Research Profile

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TOP 3
Xiaotang Jing; Ting Wang; Joseph C Glorioso; Shaohua Huang; Kathryn M Albers
The transcription factor Sox11 promotes nerve regeneration through activation of the regeneration-associated gene Sprr1a.
William F Goins; David M Krisky; James B Wechuck; Darren Wolfe; Shaohua Huang; Joseph C Glorioso
Generation of replication-competent and -defective HSV vectors.
James R Goss; Michael Cascio; William F Goins; Shaohua Huang; David M Krisky; Richard J Clarke; Jon W Johnson; Hitoshi Yokoyama; Naoki Yoshimura; Michael S Gold; Joseph C Glorioso
HSV delivery of a ligand-regulated endogenous ion channel gene to sensory neurons results in pain control following channel activation.

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All Publications

2012: Xiaotang Jing; Ting Wang; Joseph C Glorioso; Shaohua Huang; Kathryn M Albers
The transcription factor Sox11 promotes nerve regeneration through activation of the regeneration-associated gene Sprr1a.
Experimental neurology 2012;233(1):221-32.
2011: William F Goins; David M Krisky; James B Wechuck; Darren Wolfe; Shaohua Huang; Joseph C Glorioso
Generation of replication-competent and -defective HSV vectors.
Cold Spring Harbor protocols 2011;2011(5):pdb.prot5615.
2011: James R Goss; Michael Cascio; William F Goins; Shaohua Huang; David M Krisky; Richard J Clarke; Jon W Johnson; Hitoshi Yokoyama; Naoki Yoshimura; Michael S Gold; Joseph C Glorioso
HSV delivery of a ligand-regulated endogenous ion channel gene to sensory neurons results in pain control following channel activation.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(3):500-6.
2008: William F Goins; David M Krisky; James B Wechuck; Shaohua Huang; Joseph C Glorioso
Construction and production of recombinant herpes simplex virus vectors.
Methods in molecular biology (Clifton, N.J.) 2008;433():97-113.
2007: Rahul Srinivasan; Shaohua Huang; Suchita Chaudhry; Adrian Sculptoreanu; David M Krisky; Michael Cascio; Peter A Friedman; william chesney de groat; Darren Wolfe; Joseph C Glorioso
An HSV vector system for selection of ligand-gated ion channel modulators.
Nature methods 2007;4(9):733-9.
2007: R Kato; Darren Wolfe; C H Coyle; Shaohua Huang; James B Wechuck; William F Goins; David M Krisky; T Tsukamoto; Joel B Nelson; Joseph C Glorioso; Michael B Chancellor; Naoki Yoshimura
Herpes simplex virus vector-mediated delivery of glial cell line-derived neurotrophic factor rescues erectile dysfunction following cavernous nerve injury.
Gene therapy 2007;14(18):1344-52.
2007: Munmun Chattopadhyay; Marina Mata; James Goss; Darren Wolfe; Shaohua Huang; Joseph C Glorioso; David J Fink
Prolonged preservation of nerve function in diabetic neuropathy in mice by herpes simplex virus-mediated gene transfer.
Diabetologia 2007;50(7):1550-8.
2005: Munmun Chattopadhyay; Darren Wolfe; Marina Mata; Shaohua Huang; Joseph C Glorioso; David J Fink
Long-term neuroprotection achieved with latency-associated promoter-driven herpes simplex virus gene transfer to the peripheral nervous system.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(2):307-13.
2005: Shuanglin Hao; Marina Mata; Darren Wolfe; Shaohua Huang; Joseph C Glorioso; David J Fink
Gene transfer of glutamic acid decarboxylase reduces neuropathic pain.
Annals of neurology 2005;57(6):914-8.
2005: Nelson E Bennett; Jang H Kim; Darren P Wolfe; Katsumi Sasaki; Naoki Yoshimura; William F Goins; Shaohua Huang; Joel B Nelson; william chesney de groat; Joseph C Glorioso; Michael B Chancellor
Improvement in erectile dysfunction after neurotrophic factor gene therapy in diabetic rats.
The Journal of urology 2005;173(5):1820-4.
2005: Radosveta P Koldamova; Iliya Lefterov; Matthias Staufenbiel; Darren Wolfe; Shaohua Huang; Joseph C Glorioso; Michael Walter; Michael Roth; John Lazo
The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease.
The Journal of biological chemistry 2005;280(6):4079-88.
2005: J Fradette; Darren Wolfe; William F Goins; Shaohua Huang; R M Flanigan; Joseph C Glorioso
HSV vector-mediated transduction and GDNF secretion from adipose cells.
Gene therapy 2005;12(1):48-58.
2004: Veljko Puskovic; Darren Wolfe; James Goss; Shaohua Huang; Marina Mata; Joseph C Glorioso; David J Fink
Prolonged biologically active transgene expression driven by HSV LAP2 in brain in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(1):67-75.
2004: Jun Liu; Darren Wolfe; Shuanglin Hao; Shaohua Huang; Joseph C Glorioso; Marina Mata; David J Fink
Peripherally delivered glutamic acid decarboxylase gene therapy for spinal cord injury pain.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(1):57-66.
2004: Munmun Chattopadhyay; James Goss; Darren Wolfe; William C Goins; Shaohua Huang; Joseph C Glorioso; Marina Mata; David J Fink
Protective effect of herpes simplex virus-mediated neurotrophin gene transfer in cisplatin neuropathy.
Brain : a journal of neurology 2004;127(Pt 4):929-39.
2003: Atsushi Natsume; Darren Wolfe; Jian Hu; Shaohua Huang; Veljko Puskovic; Joseph C Glorioso; David J Fink; Marina Mata
Enhanced functional recovery after proximal nerve root injury by vector-mediated gene transfer.
Experimental neurology 2003;184(2):878-86.
2003: Hong Liang Guo; Darren Wolfe; Michael W Epperly; Shaohua Huang; Kaihong Liu; Joseph C Glorioso; Joel S Greenberger; David Blumberg
Gene transfer of human manganese superoxide dismutase protects small intestinal villi from radiation injury.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2003;7(2):229-35; discussion 235-6.
2003: Edward A Burton; Shaohua Huang; William F Goins; Joseph C Glorioso
Use of the herpes simplex viral genome to construct gene therapy vectors.
Methods in molecular medicine 2003;76():1-31.
2002: Atsushi Natsume; Marina Mata; Darren Wolfe; Thomas J Oligino; James Goss; Shaohua Huang; Joseph C Glorioso; David J Fink
Bcl-2 and GDNF delivered by HSV-mediated gene transfer after spinal root avulsion provide a synergistic effect.
Journal of neurotrauma 2002;19(1):61-8.
2002: Munmun Chattopadhyay; Darren Wolfe; Shaohua Huang; James Goss; Joseph C Glorioso; Marina Mata; David J Fink
In vivo gene therapy for pyridoxine-induced neuropathy by herpes simplex virus-mediated gene transfer of neurotrophin-3.
Annals of neurology 2002;51(1):19-27.
2001: Atsushi Natsume; Marina Mata; James Goss; Shaohua Huang; Darren Wolfe; Thomas J Oligino; Joseph C Glorioso; David J Fink
Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induced degeneration.
Experimental neurology 2001;169(2):231-8.