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Walter Hubbard

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Chemicals & Drugs

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Histamine Release

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Krzysztof Kamocki; Swetlana Adamsky; Evgeny Berdyshev; Elena Feinstein; Amanda Fisher; Aneta Gandjeva; Walter Hubbard; Robert G Presson; Natalia I Rush; Rubin M Tuder; Mary Van Demark; Irina Petrache
RTP801 is required for ceramide-induced cell-specific death in the murine lung.
K E Dooley; E E Bliven-Sizemore; W J Burman; Edward J Fuchs; Walter Hubbard; Y Lu; Michael THOMAS Melia; Eric Nuermberger; M Weiner; Susan E Dorman
Safety and pharmacokinetics of escalating daily doses of the antituberculosis drug rifapentine in healthy volunteers.
Yana Sandlers; Walter Hubbard; Richard O Jones; Lisa Kratz; Ann B Moser; Gerald V Raymond
Combined extraction of acyl carnitines and 26:0 lysophosphatidylcholine from dried blood spots: prospective newborn screening for X-linked adrenoleukodystrophy.

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2013: Krzysztof Kamocki; Swetlana Adamsky; Evgeny Berdyshev; Elena Feinstein; Amanda Fisher; Aneta Gandjeva; Walter Hubbard; Robert G Presson; Natalia I Rush; Rubin M Tuder; Mary Van Demark; Irina Petrache
RTP801 is required for ceramide-induced cell-specific death in the murine lung.
American journal of respiratory cell and molecular biology 2013;48(1):87-93.
2012: K E Dooley; E E Bliven-Sizemore; W J Burman; Edward J Fuchs; Walter Hubbard; Y Lu; Michael THOMAS Melia; Eric Nuermberger; M Weiner; Susan E Dorman
Safety and pharmacokinetics of escalating daily doses of the antituberculosis drug rifapentine in healthy volunteers.
Clinical pharmacology and therapeutics 2012;91(5):881-8.
2012: Yana Sandlers; Walter Hubbard; Richard O Jones; Lisa Kratz; Ann B Moser; Gerald V Raymond
Combined extraction of acyl carnitines and 26:0 lysophosphatidylcholine from dried blood spots: prospective newborn screening for X-linked adrenoleukodystrophy.
Molecular genetics and metabolism 2012;105(3):416-20.
2011: Kelly S Schweitzer; Mary Van Demark; Robert G Presson; Besem Beteck; Mary Beth Brown; Yuan Gu; Mehak Gupta; Hadi Hatoum; Walter Hubbard; Matthew J Justice; Irina Petrache
Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: role of oxidative stress and ceramides.
American journal of physiology. Lung cellular and molecular physiology 2011;301(6):L836-46.
2011: Cecilia M Devlin; Walter Hubbard; Mircea Ivan; Tim Lahm; Lina M Obeid; Mary Van Demark; Kevin C Wang; Xue Wu; Alicja Bielawska; Irina Petrache
Dihydroceramide-based response to hypoxia.
The Journal of biological chemistry 2011;286(44):38069-78.
2011: Matthias Clauss; Robert Voswinckel; Gangaraju Rajashekhar; Ninotchka L Sigua; Heinz Fehrenbach; Natalia I Rush; Kelly S Schweitzer; Ali Ö Yildirim; Krzysztof Kamocki; Amanda J Fisher; Yuan Gu; Bilal Safadi; Sandeep Nikam; Walter Hubbard; Rubin M Tuder; Homer L Twigg; Robert G Presson; Sanjay Sethi; Irina Petrache
Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice.
The Journal of clinical investigation 2011;121(6):2470-9.
2010: Daniela N Petrusca; Yuan Gu; Jeremy J Adamowicz; Natalia I Rush; Walter Hubbard; Patricia A Smith; Evgeny Berdyshev; Konstantin G Birukov; Chao-Hung Lee; Rubin M Tuder; Homer L Twigg; R William Vandivier; Irina Petrache
Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages.
The Journal of biological chemistry 2010;285(51):40322-32.
2010: Lindsay B Avery; Teresa Parsons; DAVID MEYERS; Walter Hubbard
A highly sensitive ultra performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) technique for quantitation of protein free and bound efavirenz (EFV) in human seminal and blood plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(31):3217-24.
2010: J Chen; R C Garner; Lawrence Lee; M Seymour; Edward J Fuchs; Walter Hubbard; Teresa Parsons; G E Pakes; Courtney V Fletcher; Charles Flexner
Accelerator mass spectrometry measurement of intracellular concentrations of active drug metabolites in human target cells in vivo.
Clinical pharmacology and therapeutics 2010;88(6):796-800.
2010: Khalil J Diab; Jeremy J Adamowicz; Krzysztof Kamocki; Natalia I Rush; Jana Garrison; Yuan Gu; Kelly S Schweitzer; Anastasia Skobeleva; Gangaraju Rajashekhar; Walter Hubbard; Evgeny Berdyshev; Irina Petrache
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema.
American journal of respiratory and critical care medicine 2010;181(4):344-52.
2009: Walter Hubbard; Ann B Moser; Anita C Liu; Richard O Jones; Steven J Steinberg; Fred Lorey; SUSAN PANNY; Robert F Vogt; Daniela Macaya; Coleman T Turgeon; Silvia Tortorelli; Gerald V Raymond
Newborn screening for X-linked adrenoleukodystrophy (X-ALD): validation of a combined liquid chromatography-tandem mass spectrometric (LC-MS/MS) method.
Molecular genetics and metabolism 2009;97(3):212-20.
2008: Irina Petrache; Terry R Medler; Amy T Richter; Krzysztof Kamocki; Ugonma Chukwueke; Lijie Zhen; Yuan Gu; Jeremy Adamowicz; Kelly S Schweitzer; Walter Hubbard; Evgeny Berdyshev; Giuseppe Lungarella; Rubin M Tuder
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide.
American journal of physiology. Lung cellular and molecular physiology 2008;295(1):L44-53.
2008: Terry R Medler; Daniela N Petrusca; Patty J Lee; Walter Hubbard; Evgeny Berdyshev; Jarrett Skirball; Krzysztof Kamocki; Edward Schuchman; Rubin M Tuder; Irina Petrache
Apoptotic sphingolipid signaling by ceramides in lung endothelial cells.
American journal of respiratory cell and molecular biology 2008;38(6):639-46.
2008: Alejandra Bosco; Denise M Inman; Michael R Steele; Guangming Wu; Ileana Soto; Nicholas Marsh-Armstrong; Walter Hubbard; David J Calkins; Philip J Horner; Monica L Vetter
Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma.
Investigative ophthalmology & visual science 2008;49(4):1437-46.
2008: Hidenori Yokoi; OKSOON CHOI; Walter Hubbard; Hyun-Sil Lee; Brendan J Canning; Hyun H Lee; Seung-Duk Ryu; Stephan von Gunten; Carol A Bickel; Sherry A Hudson; Donald MacGlashan; Bruce S Bochner
Inhibition of FcepsilonRI-dependent mediator release and calcium flux from human mast cells by sialic acid-binding immunoglobulin-like lectin 8 engagement.
The Journal of allergy and clinical immunology 2008;121(2):499-505.e1.
2007: Steve N Georas; Evgeny Berdyshev; Walter Hubbard; Irina A Gorshkova; Peter Usatyuk; Bahman Saatian; Allen C Myers; M A Williams; HUIQING XIAO; Mark C Liu; Viswanathan Natarajan
Lysophosphatidic acid is detectable in human bronchoalveolar lavage fluids at baseline and increased after segmental allergen challenge.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(3):311-22.
2006: Evgeny Berdyshev; Irina A Gorshkova; Peter Usatyuk; Yutong Zhao; Bahman Saatian; Walter Hubbard; Viswanathan Natarajan
De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells.
Cellular signalling 2006;18(10):1779-92.
2006: Walter Hubbard; Ann B Moser; Silvia Tortorelli; Anita Liu; David Jones; Hugo Moser
Combined liquid chromatography-tandem mass spectrometry as an analytical method for high throughput screening for X-linked adrenoleukodystrophy and other peroxisomal disorders: preliminary findings.
Molecular genetics and metabolism 2006;89(1-2):185-7.
2005: Jianguo Li; Laura N Thorne; Naresh M Punjabi; Cheuk-Kwan Sun; Alan R Schwartz; Philip L. Smith; Rafael L Marino; Annabelle Rodriguez; Walter Hubbard; Christopher P O'Donnell; Vsevolod Y Polotsky
Intermittent hypoxia induces hyperlipidemia in lean mice.
Circulation research 2005;97(7):698-706.
2005: Irina Petrache; Viswanathan Natarajan; Lijie Zhen; Terry R Medler; Amy T Richter; Cecilia Cho; Walter Hubbard; Evgeny Berdyshev; Rubin M Tuder
Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice.
Nature medicine 2005;11(5):491-8.
2005: Evgeny Berdyshev; Irina A Gorshkova; Joe G. N. Garcia; Viswanathan Natarajan; Walter Hubbard
Quantitative analysis of sphingoid base-1-phosphates as bisacetylated derivatives by liquid chromatography-tandem mass spectrometry.
Analytical biochemistry 2005;339(1):129-36.
2004: Francis M Giardiello; Robert A Casero; Stanley R Hamilton; Linda M Hylind; Jill D Trimbath; Deborah E Geiman; Katharine R Judge; Walter Hubbard; G Johan A Offerhaus; Yang Vincent
Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis.
Gastroenterology 2004;126(2):425-31.
2003: Walter Hubbard; Andrew E Blum; Carol A Bickel; Nicola M Heller; Robert P Schleimer
Detection and quantitation of fatty acid acyl conjugates of triamcinolone acetonide via gas chromatography-electron-capture negative-ion mass spectrometry.
Analytical biochemistry 2003;322(2):243-50.
2002: Francis M Giardiello; Yang Vincent; Linda M Hylind; Anne J Krush; Gloria M Petersen; Jill D Trimbath; Steven Piantadosi; Elizabeth Garrett-Mayer; Deborah E Geiman; Walter Hubbard; G Johan A Offerhaus; Stanley R Hamilton
Primary chemoprevention of familial adenomatous polyposis with sulindac.
The New England journal of medicine 2002;346(14):1054-9.
2001: Mark C Liu; David Proud; Lawrence M Lichtenstein; Walter Hubbard; Bruce S Bochner; B A Stealey; L Breslin; HUIQING XIAO; LR Freidhoff; John T Schroeder; Robert P Schleimer
Effects of prednisone on the cellular responses and release of cytokines and mediators after segmental allergen challenge of asthmatic subjects.
The Journal of allergy and clinical immunology 2001;108(1):29-38.
2001: Walter Hubbard; Mark C Liu; Carol A Bickel; Domenick Argenti; Donald Heald; Robert P Schleimer
Measurement of low picomolar levels of triamcinolone acetonide in human bronchoalveolar lavage fluid by gas chromatography-electron-capture negative-ion mass spectrometry.
Analytical biochemistry 2001;290(1):18-25.
2000: RS Peebles; Alkis Togias; Carol A Bickel; FB Diemer; Walter Hubbard; Robert P Schleimer
Endogenous glucocorticoids and antigen-induced acute and late phase pulmonary responses.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2000;30(9):1257-65.
2000: Yang Vincent; Deborah E Geiman; Walter Hubbard; Ernst Wm Spannhake; Linda M Hylind; Stanley R Hamilton; Francis M Giardiello
Tissue prostanoids as biomarkers for chemoprevention of colorectal neoplasia: correlation between prostanoid synthesis and clinical response in familial adenomatous polyposis.
Prostaglandins & other lipid mediators 2000;60(1-3):83-96.
1999: Katsushi Miura; John T Schroeder; Walter Hubbard; Donald MacGlashan
Extracellular signal-regulated kinases regulate leukotriene C4 generation, but not histamine release or IL-4 production from human basophils.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(7):4198-206.
1998: Katsushi Miura; Walter Hubbard; Donald MacGlashan
Phosphorylation of cytosolic phospholipase A2 by IL-3 is associated with increased free arachidonic acid generation and leukotriene C4 release in human basophils.
The Journal of allergy and clinical immunology 1998;102(3):512-20.
1998: Jeffrey R Jackson; Brian J Bolognese; C A Mangar; Walter Hubbard; Lisa A Marshall; James D Winkler
The role of platelet activating factor and other lipid mediators in inflammatory angiogenesis.
Biochimica et biophysica acta 1998;1392(1):145-52.
1998: Yang Vincent; Janiel M Shields; Stanley R Hamilton; Ernst Wm Spannhake; Walter Hubbard; Linda M Hylind; CR Robinson; Francis M Giardiello
Size-dependent increase in prostanoid levels in adenomas of patients with familial adenomatous polyposis.
Cancer research 1998;58(8):1750-3.
1998: T R Hundley; Lisa A Marshall; Walter Hubbard; Donald MacGlashan
Characteristics of arachidonic acid generation in human basophils: relationship between the effects of inhibitors of secretory phospholipase A2 activity and leukotriene C4 release.
The Journal of pharmacology and experimental therapeutics 1998;284(3):847-57.
1998: Francis M Giardiello; Ernst Wm Spannhake; Raymond DuBois; Linda M Hylind; CR Robinson; Walter Hubbard; Stanley R Hamilton; Yang Vincent
Prostaglandin levels in human colorectal mucosa: effects of sulindac in patients with familial adenomatous polyposis.
Digestive diseases and sciences 1998;43(2):311-6.
1997: A Oriente; T Hundley; Walter Hubbard; Donald MacGlashan
Preliminary characterization of diacylglycerol generation in human basophils: temporal relationship to histamine release and resolution of degranulation.
Journal of leukocyte biology 1997;61(5):637-42.
1996: Joan M Bathon; F H Chilton; Walter Hubbard; M C Towns; N J Solan; David Proud
Mechanisms of prostanoid synthesis in human synovial cells: cytokine-peptide synergism.
Inflammation 1996;20(5):537-54.
1996: Robert M Naclerio; Walter Hubbard; Lawrence M Lichtenstein; Anne Kagey-Sobotka; David Proud
Origin of late phase histamine release.
The Journal of allergy and clinical immunology 1996;98(4):721-3.
1996: Walter Hubbard; T R Hundley; A Oriente; Donald MacGlashan
Quantitation of 1-stearoyl-2-arachidonoyl-sn-3-glycerol in human basophils via gas chromatography-negative ion chemical ionization mass spectrometry.
Analytical biochemistry 1996;236(2):309-21.
1996: Floyd H Chilton; F J Averill; Walter Hubbard; Alfred Fonteh; M Triggiani; Mark C Liu
Antigen-induced generation of lyso-phospholipids in human airways.
The Journal of experimental medicine 1996;183(5):2235-45.
1996: Martin Wagenmann; Fuad M Baroody; M Desrosiers; Walter Hubbard; S Ford; Lawrence M Lichtenstein; Robert M Naclerio
Unilateral nasal allergen challenge leads to bilateral release of prostaglandin D2.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1996;26(4):371-8.
1995: G G Weinmann; Mark C Liu; David Proud; M Weidenbach-Gerbase; Walter Hubbard; R Frank
Ozone exposure in humans: inflammatory, small and peripheral airway responses.
American journal of respiratory and critical care medicine 1995;152(4 Pt 1):1175-82.
1994: Bradley J Undem; Lawrence M Lichtenstein; Walter Hubbard; Sonya N Meeker; J L Ellis
Recombinant stem cell factor-induced mast cell activation and smooth muscle contraction in human bronchi.
American journal of respiratory cell and molecular biology 1994;11(6):646-50.
1994: J L Ellis; Walter Hubbard; Sonya N Meeker; Bradley J Undem
Ragweed antigen E and anti-IgE in human central versus peripheral isolated bronchi.
American journal of respiratory and critical care medicine 1994;150(3):717-23.
1994: L B Fernandes; Walter Hubbard; Bradley J Undem
Release of inflammatory mediators from guinea pig trachea by electrical field stimulation: lack of neuronal involvement.
The Journal of pharmacology and experimental therapeutics 1994;270(3):1166-70.
1994: Walter Hubbard; CA Bickel; Robert P Schleimer
Simultaneous quantitation of endogenous levels of cortisone and cortisol in human nasal and bronchoalveolar lavage fluids and plasma via gas chromatography-negative ion chemical ionization mass spectrometry.
Analytical biochemistry 1994;221(1):109-17.
1994: Arthur N Freed; C Omori; Walter Hubbard; N FRANKLIN ADKINSON
Dry air- and hypertonic aerosol-induced bronchoconstriction and cellular responses in the canine lung periphery.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1994;7(7):1308-16.
1994: C Kroegel; Mark C Liu; Walter Hubbard; Lawrence M Lichtenstein; Bruce S Bochner
Blood and bronchoalveolar eosinophils in allergic subjects after segmental antigen challenge: surface phenotype, density heterogeneity, and prostanoid production.
The Journal of allergy and clinical immunology 1994;93(4):725-34.
1994: M H Shin; F J Averill; Walter Hubbard; Floyd H Chilton; Fuad M Baroody; Mark C Liu; Robert M Naclerio
Nasal allergen challenge generates 1-0-hexadecyl-2-lyso-sn-glycero-3-phosphocholine.
American journal of respiratory and critical care medicine 1994;149(3 Pt 1):660-6.
1993: Donald MacGlashan; Walter Hubbard
IL-3 alters free arachidonic acid generation in C5a-stimulated human basophils.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(11):6358-69.
1993: Douglas W P Hay; Mark A Luttmann; Walter Hubbard; Bradley J Undem
Endothelin receptor subtypes in human and guinea-pig pulmonary tissues.
British journal of pharmacology 1993;110(3):1175-83.
1993: Douglas W P Hay; Walter Hubbard; Bradley J Undem
Relative contributions of direct and indirect mechanisms mediating endothelin-induced contraction of guinea-pig trachea.
British journal of pharmacology 1993;110(3):955-62.
1993: Karen S Lindeman; N Downey; Mark C Liu; Walter Hubbard; A Kagey-Sobotka; Carol A Hirshman
Importance of prostanoids in calcium chelator-induced airway constriction.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(3):1110-6.
1993: Douglas W P Hay; Walter Hubbard; Bradley J Undem
Endothelin-induced contraction and mediator release in human bronchus.
British journal of pharmacology 1993;110(1):392-8.
1993: Bradley J Undem; Walter Hubbard; Daniel Weinreich
Immunologically induced neuromodulation of guinea pig nodose ganglion neurons.
Journal of the autonomic nervous system 1993;44(1):35-44.
1993: James D Winkler; Chiu-Mei Sung; Walter Hubbard; Floyd H Chilton
Influence of arachidonic acid on indices of phospholipase A2 activity in the human neutrophil.
The Biochemical journal 1993;291 ( Pt 3)():825-31.
1993: Floyd H Chilton; M Patel; Alfred Fonteh; Walter Hubbard; M Triggiani
Dietary n-3 fatty acid effects on neutrophil lipid composition and mediator production. Influence of duration and dosage.
The Journal of clinical investigation 1993;91(1):115-22.
1992: M Triggiani; Robert P Schleimer; K Tomioka; Walter Hubbard; Floyd H Chilton
Characterization of platelet-activating factor synthesized by normal and granulocyte-macrophage colony-stimulating factor-primed human eosinophils.
Immunology 1992;77(4):500-4.
1992: James D Winkler; Chiu-Mei Sung; Walter Hubbard; Floyd H Chilton
Evidence for different mechanisms involved in the formation of lyso platelet-activating factor and the calcium-dependent release of arachidonic acid from human neutrophils.
Biochemical pharmacology 1992;44(10):2055-66.
1992: Dallas M Hyde; Walter Hubbard; V Wong; Reen Wu; Kent E Pinkerton; Charles G Plopper
Ozone-induced acute tracheobronchial epithelial injury: relationship to granulocyte emigration in the lung.
American journal of respiratory cell and molecular biology 1992;6(5):481-97.
1992: F J Averill; Walter Hubbard; David Proud; G J Gleich; Mark C Liu
Platelet activation in the lung after antigen challenge in a model of allergic asthma.
The American review of respiratory disease 1992;145(3):571-6.
1992: X Y Yu; Walter Hubbard; Ernst Wm Spannhake
Inhibition of canine tracheal smooth muscle by mediators from cultured bronchial epithelial cells.
The American journal of physiology 1992;262(2 Pt 1):L229-34.
1991: W A Massey; Walter Hubbard; Mark C Liu; Anne Kagey-Sobotka; P Cooper; Lawrence M Lichtenstein
Profile of prostanoid release following antigen challenge in vivo in the skin of man.
The British journal of dermatology 1991;125(6):529-34.
1991: T Nakamura; Alfred Fonteh; Walter Hubbard; M Triggiani; N Inagaki; TERUKO ISHIZAKA; Floyd H Chilton
Arachidonic acid metabolism during antigen and ionophore activation of the mouse bone marrow derived mast cell.
Biochimica et biophysica acta 1991;1085(2):191-200.
1991: W A Massey; C B Guo; A M Dvorak; Walter Hubbard; B S Bhagavan; V L Cohan; J A Warner; Anne Kagey-Sobotka; Lawrence M Lichtenstein
Human uterine mast cells. Isolation, purification, characterization, ultrastructure, and pharmacology.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(5):1621-7.
1991: Thomas E Eling; Wayne C Glasgow; J F Curtis; Walter Hubbard; J A Handler
Studies on the reduction of endogenously generated prostaglandin G2 by prostaglandin H synthase.
The Journal of biological chemistry 1991;266(19):12348-55.
1991: Mark C Liu; Walter Hubbard; David Proud; B A Stealey; S J Galli; Anne Kagey-Sobotka; Eugene R Bleecker; Lawrence M Lichtenstein
Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permeability changes.
The American review of respiratory disease 1991;144(1):51-8.
1991: A M Majchel; David Proud; Walter Hubbard; Robert M Naclerio
Histamine stimulation of the nasal mucosa does not induce prostaglandin or leukotriene generation or induce methacholine hyperresponsiveness.
International archives of allergy and applied immunology 1991;95(2-3):149-55.
1990: T L McLemore; C L Litterst; B P Coudert; Mark C Liu; Walter Hubbard; S Adelberg; M Czerwinski; N A McMahon; J C Eggleston; Michael R Boyd
Metabolic activation of 4-ipomeanol in human lung, primary pulmonary carcinomas, and established human pulmonary carcinoma cell lines.
Journal of the National Cancer Institute 1990;82(17):1420-6.
1990: T L McLemore; S Adelberg; Mark C Liu; N A McMahon; S J Yu; Walter Hubbard; M Czerwinski; T G Wood; R Storeng; Ronald A Lubet
Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas.
Journal of the National Cancer Institute 1990;82(16):1333-9.
1990: Mark C Liu; Eugene R Bleecker; L M Lichtenstein; A Kagey-Sobotka; Y Niv; T L McLemore; Solbert Permutt; David Proud; Walter Hubbard
Evidence for elevated levels of histamine, prostaglandin D2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthma.
The American review of respiratory disease 1990;142(1):126-32.
1990: M Triggiani; Walter Hubbard; Floyd H Chilton
Synthesis of 1-acyl-2-acetyl-sn-glycero-3-phosphocholine by an enriched preparation of the human lung mast cell.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(12):4773-80.
1990: Bradley J Undem; Walter Hubbard; E P Christian; Daniel Weinreich
Mast cells in the guinea pig superior cervical ganglion: a functional and histological assessment.
Journal of the autonomic nervous system 1990;30(1):75-87.
1989: T L McLemore; S Adelberg; M Czerwinski; Walter Hubbard; S J Yu; R Storeng; T G Wood; Ronald Hines; Michael R Boyd
Altered regulation of the cytochrome P4501A1 gene: novel inducer-independent gene expression in pulmonary carcinoma cell lines.
Journal of the National Cancer Institute 1989;81(23):1787-94.
1989: L Churchill; Floyd H Chilton; James Resau; Rebecca Bascom; Walter Hubbard; David Proud
Cyclooxygenase metabolism of endogenous arachidonic acid by cultured human tracheal epithelial cells.
The American review of respiratory disease 1989;140(2):449-59.
1989: J A Warner; Stephen P Peters; Lawrence M Lichtenstein; Walter Hubbard; K B Yancey; H C Stevenson; P J Miller; Donald MacGlashan
Differential release of mediators from human basophils: differences in arachidonic acid metabolism following activation by unrelated stimuli.
Journal of leukocyte biology 1989;45(6):558-71.
1989: Walter Hubbard; M C Alley; G N Gray; K C Green; T L McLemore; Michael R Boyd
Evidence for prostanoid biosynthesis as a biochemical feature of certain subclasses of non-small cell carcinomas of the lung as determined in established cell lines derived from human lung tumors.
Cancer research 1989;49(4):826-32.
1988: Walter Hubbard; M C Alley; T L McLemore; Michael R Boyd
Profiles of prostaglandin biosynthesis in sixteen established cell lines derived from human lung, colon, prostate, and ovarian tumors.
Cancer research 1988;48(17):4770-5.
1988: T L McLemore; Walter Hubbard; C L Litterst; Mark C Liu; S Miller; N A McMahon; J C Eggleston; Michael R Boyd
Profiles of prostaglandin biosynthesis in normal lung and tumor tissue from lung cancer patients.
Cancer research 1988;48(11):3140-7.
1988: Walter Hubbard; M C Alley; T L McLemore; Michael R Boyd
Evidence for thromboxane biosynthesis in established cell lines derived from human lung adenocarcinomas.
Cancer research 1988;48(10):2674-7.
1988: Mark C Liu; Eugene R Bleecker; David Proud; T L McLemore; Walter Hubbard
Profiling of bisenoic prostaglandins and thromboxane B2 in bronchoalveolar fluid from the lower respiratory tract of human subjects by combined capillary gas chromatography-mass spectrometry.
Prostaglandins 1988;35(1):67-79.
1987: I D Lawrence; J A Warner; V L Cohan; Walter Hubbard; Anne Kagey-Sobotka; Lawrence M Lichtenstein
Purification and characterization of human skin mast cells. Evidence for human mast cell heterogeneity.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(9):3062-9.
1987: T L McLemore; Mark C Liu; P C Blacker; M Gregg; M C Alley; B J Abbott; Robert H Shoemaker; Mark E Bohlman; C C Litterst; Walter Hubbard
Novel intrapulmonary model for orthotopic propagation of human lung cancers in athymic nude mice.
Cancer research 1987;47(19):5132-40.
1986: Walter Hubbard; C L Litterst; Mark C Liu; Eugene R Bleecker; J C Eggleston; T L McLemore; M R Boyd
Profiling of prostaglandin biosynthesis in biopsy fragments of human lung carcinomas and normal human lung by capillary gas chromatography-negative ion chemical ionization mass spectrometry.
Prostaglandins 1986;32(6):889-906.
1984: W E Serafin; J A Oates; Walter Hubbard
Metabolism of leukotriene B4 in the monkey. Identification of the principal nonvolatile metabolite in the urine.
Prostaglandins 1984;27(6):899-911.
1984: R L Forti; W M Mitchell; Walter Hubbard; R J Workman; J T Forbes
Pleiotropic activities of human interferons are mediated by multiple response pathways.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(1):170-4.
1983: R L Forti; W M Mitchell; R J Workman; J T Forbes; Walter Hubbard
A functional cyclooxygenase enzyme is not required for mediation of the pleiotropic effects of human alpha or beta interferon.
Prostaglandins 1983;26(3):409-20.
1983: A J Hough; Walter Hubbard; J A Oates
VX2 carcinoma, pulmonary metastases, and neutrophilic leukocytosis. Possible animal model of tumor-associated granulocytosis.
The American journal of pathology 1983;112(2):231-7.
1983: J Turk; W R Henderson; S J Klebanoff; Walter Hubbard
Iodination of arachidonic acid mediated by eosinophil peroxidase, myeloperoxidase and lactoperoxidase. Identification and comparison of products.
Biochimica et biophysica acta 1983;751(2):189-200.
1982: Martin Ogletree; J A Oates; Kenneth L Brigham; Walter Hubbard
Evidence for pulmonary release of 5-hydroxyeicosatetraenoic acid (5-hete) during endotoxemia in unanesthetized sheep.
Prostaglandins 1982;23(4):459-68.
1982: Martin Ogletree; K Schlesinger; Mary D Nettleman; Walter Hubbard
Measurement of 5-hydroxyeicosatetraenoic acid (5-HETE) in biological fluids by GC-MS.
Methods in enzymology 1982;86():607-12.
1982: Walter Hubbard
Quantitation of 15-Keto-13,14-dihydro-PGE2 in plasma by GC-MS1.
Methods in enzymology 1982;86():571-8.
1982: Walter Hubbard; M A Phillips; D F Taber
Selective synthesis of octadeuterated (+/-)-5-HETE for use in GC-MS quantitation of 5-HETE.
Prostaglandins 1982;23(1):61-5.
1981: J M Boeynaems; D Pelster; J A Oates; Walter Hubbard
Novel transformations of arachidonic acid by the rat thyroid in vitro.
Biochimica et biophysica acta 1981;665(3):623-7.
1981: D F Taber; M A Phillips; Walter Hubbard
Preparation of deuterated arachidonic acid.
Prostaglandins 1981;22(3):349-52.
1981: E J Goetzl; J M Boeynaems; J A Oates; Walter Hubbard
Stimulus-specificity of the chemotactic deactivation of human neutrophils by lipoxygenase products of arachidonic acid.
Prostaglandins 1981;22(2):279-88.
1981: J M Boeynaems; J T Watson; J A Oates; Walter Hubbard
Iodination of docosahexaenoic acid by lactoperoxidase and thyroid gland in vitro: formation of an lodolactone.
Lipids 1981;16(5):323-7.
1981: J M Boeynaems; D Reagan; Walter Hubbard
Lactoperoxidase-catalyzed iodination of arachidonic acid: formation of macrolides.
Lipids 1981;16(4):246-9.
1981: L J Roberts; B J Sweetman; R L Maas; Walter Hubbard; J A Oates
Clinical application of PG and TX metabolite quantification.
Progress in lipid research 1981;20():117-21.
1980: J M Boeynaems; Walter Hubbard
Transformation of arachidonic acid into an iodolactone by the rat thyroid.
The Journal of biological chemistry 1980;255(19):9001-4.
1980: Walter Hubbard; A J Hough; A R Brash; J T Watson; J A Oates
Metabolism of linoleic and arachidonic acids in VX2 carcinoma tissue: identification of monohydroxy octadecadienoic acids and monohydroxy eicosatetraenoic acids.
Prostaglandins 1980;20(3):431-47.
1980: Walter Hubbard; A J Hough; R M Johnson; J A Oates
The site of VX2 tumor transplantation affects the development of hypercalcemia in rabbits.
Prostaglandins 1980;19(6):881-9.
1980: J M Boeynaems; A R Brash; J A Oates; Walter Hubbard
Preparation and assay of monohydroxy-eicosatetraenoic acids.
Analytical biochemistry 1980;104(2):259-67.
1980: E J Goetzl; A R Brash; A I Tauber; J A Oates; Walter Hubbard
Modulation of human neutrophil function by monohydroxy-eicosatetraenoic acids.
Immunology 1980;39(4):491-501.
1980: Walter Hubbard; A Hough; A R Brash; R M Johnson; J A Oates
The VX-2 carcinoma: humoral effects and arachidonic acid metabolism.
Advances in prostaglandin and thromboxane research 1980;6():525-7.
1980: J M Boeynaems; J A Oates; Walter Hubbard
Preparation and characterization of hydroperoxy-eicosatetraenoic acids (HPETEs).
Prostaglandins 1980;19(1):87-97.
1979: J G Gerber; Walter Hubbard; A S Nies
Uterine vein prostaglandin levels in late pregnant dogs.
Prostaglandins 1979;17(4):623-7.
1979: L P Gangarosa; Walter Hubbard; C T Hung; N H Park
Relative vasodilator potency of ATP, ADP, AMP and adenosine (Ado) in the cat hind limb.
Archives internationales de pharmacodynamie et de thérapie 1979;238(1):114-23.
1979: J G Gerber; Walter Hubbard; A S Nies
The role of renal metabolism of PGE2 in determining its activity as a renal vasodilator in the dog.
Prostaglandins 1979;17(3):323-36.
1979: L J Roberts; Walter Hubbard; Z T Bloomgarden; X Y Bertagna; T J McKenna; D Rabinowitz; J A Oates
Prostaglandins: role in the humoral manifestations of medullary carcinoma of the thyroid and inhibition by somatostatin.
Transactions of the Association of American Physicians 1979;92():286-91.
1978: J G Gerber; R A Branch; Walter Hubbard; A S Nies
Indomethacin is a placental vasodilator in the dog. The effect of prostaglandin inhibition.
The Journal of clinical investigation 1978;62(1):14-9.
1978: J G Gerber; Walter Hubbard; R A Branch; A S Nies
The lack of an effect of furosemide on uterine prostaglandin metabolism in vivo.
Prostaglandins 1978;15(4):663-70.
1977: H W Seyberth; Walter Hubbard; O Oelz; B J Sweetman; J T Watson; J A Oates
Prostaglandin-mediated hypercalcemia in the VX2 carcinoma-bearing rabbit.
Prostaglandins 1977;14(2):319-31.
1977: L G Raisz; J W Dietrich; H A Simmons; H W Seyberth; Walter Hubbard; J A Oates
Effect of prostaglaidin endoperoxides and metabolites on bone resorption in vitro.
Nature 1977;267(5611):532-4.
1976: R A Goodwin; F T Owens; J D Snell; Walter Hubbard; R D Buchanan; R T Terry; R M Des Prez
Chronic pulmonary histoplasmosis.
Medicine 1976;55(6):413-52.
1976: Walter Hubbard; J T Watson
Determination of 15-keto-13,14-dihydro-metabolites of PGE2 and PGF2alpha in plasma using high performance liquid chromatography and gas chromatography-mass spectrometry.
Prostaglandins 1976;12(1):21-35.
1975: R B Strecker; Walter Hubbard; A M Michelakis
Dissociation constant of the norepinephrine-receptor complex in normotensive and hypertensive rats.
Circulation research 1975;37(5):658-63.
1972: L Hurwitz; Walter Hubbard; S Little
The relationship between the drug-receptor interaction and calcium transport in smooth muscle.
The Journal of pharmacology and experimental therapeutics 1972;183(1):117-26.
1965: M W Jordin; W D Easterly; T E Winningham; Walter Hubbard
Synthesis and pharmacological properties of some fluorine-containing amide derivatives.
Journal of pharmaceutical sciences 1965;54(8):1190-3.