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Wayne Hubbell

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TOP 3
Sergey A Vishnivetskiy; Wayne L Hubbell; Thomas Tomasiak; Maria C Palazzo; Christian Altenbach; Evan K Brooks; Qiuyan Chen; Vsevolod V Gurevich
Engineering visual arrestin-1 with special functional characteristics.
Miyeon Kim; Jens Meiler; Takefumi Morizumi; Ned Van Eps; Sergey A Vishnivetskiy; Xuanzhi Zhan; Nathan S Alexander; Whitney M Cleghorn; Oliver P Ernst; Vsevolod V Gurevich; Susan M Hanson; Wayne L Hubbell
Conformation of receptor-bound visual arrestin.
Carlos J López; Shirley Oga; Wayne L Hubbell
Mapping molecular flexibility of proteins with site-directed spin labeling: a case study of myoglobin.

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2013: Sergey A Vishnivetskiy; Wayne L Hubbell; Thomas Tomasiak; Maria C Palazzo; Christian Altenbach; Evan K Brooks; Qiuyan Chen; Vsevolod V Gurevich
Engineering visual arrestin-1 with special functional characteristics.
The Journal of biological chemistry 2013;288(5):3394-405.
2012: Miyeon Kim; Jens Meiler; Takefumi Morizumi; Ned Van Eps; Sergey A Vishnivetskiy; Xuanzhi Zhan; Nathan S Alexander; Whitney M Cleghorn; Oliver P Ernst; Vsevolod V Gurevich; Susan M Hanson; Wayne L Hubbell
Conformation of receptor-bound visual arrestin.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(45):18407-12.
2012: Carlos J López; Shirley Oga; Wayne L Hubbell
Mapping molecular flexibility of proteins with site-directed spin labeling: a case study of myoglobin.
Biochemistry 2012;51(33):6568-83.
2012: Zhongyu Yang; Jay L Zweier; Peter Borbat; Jack H Freed; Yangping Liu; Wayne L Hubbell
Pulsed ESR dipolar spectroscopy for distance measurements in immobilized spin labeled proteins in liquid solution.
Journal of the American Chemical Society 2012;134(24):9950-2.
2011: Mark R Fleissner; Kálmán Hideg; Michael D Bridges; Evan K Brooks; Duilio Cascio; Tamás Kálai; Wayne L Hubbell
Structure and dynamics of a conformationally constrained nitroxide side chain and applications in EPR spectroscopy.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(39):16241-6.
2011: Sergey A Vishnivetskiy; Derek J Francis; Luis E Gimenez; Susan M Hanson; Wayne L Hubbell; Candice S Klug; Vsevolod V Gurevich
Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins.
The Journal of biological chemistry 2011;286(27):24288-99.
2011: Kurt Januszyk; Sandra L Martin; Fa-Kuen Shieh; Christian Altenbach; Lara Atchabahian; Mark R Fleissner; Feng Guo; Wayne L Hubbell; Robert T Clubb
Site-directed spin labeling electron paramagnetic resonance study of the ORF1 protein from a mouse L1 retrotransposon.
Protein science : a publication of the Protein Society 2011;20(7):1231-43.
2011: Ned Van Eps; Nathan Alexander; Heidi E Hamm; Ali I Kaya; Scott Meier; Jens Meiler; Anita M Preininger; Wayne L Hubbell
Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(23):9420-4.
2011: Miyeon Kim; Susan M Hanson; Sergey A Vishnivetskiy; Xiufeng Song; Whitney M Cleghorn; Wayne L Hubbell; Vsevolod V Gurevich
Robust self-association is a common feature of mammalian visual arrestin-1.
Biochemistry 2011;50(12):2235-42.
2011: John McCoy; Wayne L Hubbell
High-pressure EPR reveals conformational equilibria and volumetric properties of spin-labeled proteins.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(4):1331-6.
2011: Dora Toledo Warshaviak; Laura Serbulea; Kendall N Houk; Wayne L Hubbell
Conformational analysis of a nitroxide side chain in an α-helix with density functional theory.
The journal of physical chemistry. B 2011;115(2):397-405.
2010: Sergey A Vishnivetskiy; Derek Francis; Ned Van Eps; Miyeon Kim; Susan M Hanson; Candice S Klug; Wayne L Hubbell; Vsevolod V Gurevich
The role of arrestin alpha-helix I in receptor binding.
Journal of molecular biology 2010;395(1):42-54.
2009: Mark R Fleissner; Eric M Brustad; Tamás Kálai; Christian Altenbach; Duilio Cascio; Francis B Peters; Kálmán Hideg; Sebastian Peuker; Peter G Schultz; Wayne L Hubbell
Site-directed spin labeling of a genetically encoded unnatural amino acid.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(51):21637-42.
2009: Carlos J López; Mark R Fleissner; Zhefeng Guo; Ana K Kusnetzow; Wayne L Hubbell
Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins.
Protein science : a publication of the Protein Society 2009;18(8):1637-52.
2009: Mark R Fleissner; Duilio Cascio; Wayne L Hubbell
Structural origin of weakly ordered nitroxide motion in spin-labeled proteins.
Protein science : a publication of the Protein Society 2009;18(5):893-908.
2009: Damon Scoville; John D Stamm; Christian Altenbach; Alexander Shvetsov; Kaveh Kokabi; Peter A Rubenstein; Wayne L Hubbell; Emil Reisler
Effects of binding factors on structural elements in F-actin.
Biochemistry 2009;48(2):370-8.
2008: Susan M Hanson; Eric S Dawson; Derek J Francis; Ned Van Eps; Candice S Klug; Wayne L Hubbell; Jens Meiler; Vsevolod V Gurevich
A model for the solution structure of the rod arrestin tetramer.
Structure (London, England : 1993) 2008;16(6):924-34.
2008: Christian Altenbach; Ana Karin Kusnetzow; Oliver P Ernst; Klaus Peter Hofmann; Wayne L Hubbell
High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(21):7439-44.
2008: Zhefeng Guo; Duilio Cascio; Kálmán Hideg; Wayne L Hubbell
Structural determinants of nitroxide motion in spin-labeled proteins: solvent-exposed sites in helix B of T4 lysozyme.
Protein science : a publication of the Protein Society 2008;17(2):228-39.
2008: Susan M Hanson; Sergey A Vishnivetskiy; Wayne L Hubbell; Vsevolod V Gurevich
Opposing effects of inositol hexakisphosphate on rod arrestin and arrestin2 self-association.
Biochemistry 2008;47(3):1070-5.
2007: Irina Smirnova; Vladimir Kasho; Jun-Yong Choe; Christian Altenbach; Wayne L Hubbell; H Ronald Kaback
Sugar binding induces an outward facing conformation of LacY.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(42):16504-9.
2007: Zhefeng Guo; Duilio Cascio; Kálmán Hideg; Támás Kálái; Wayne L Hubbell
Structural determinants of nitroxide motion in spin-labeled proteins: tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein science : a publication of the Protein Society 2007;16(6):1069-86.
2007: Jun Sasaki; Brian J Phillips; Xinpu Chen; Ned Van Eps; Ah-Lim Tsai; Wayne L Hubbell; John L Spudich
Different dark conformations function in color-sensitive photosignaling by the sensory rhodopsin I-HtrI complex.
Biophysical journal 2007;92(11):4045-53.
2007: William M Oldham; Ned Van Eps; Anita M Preininger; Wayne L Hubbell; Heidi E Hamm
Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):7927-32.
2007: Susan M Hanson; Ned Van Eps; Derek J Francis; Christian Altenbach; Sergey A Vishnivetskiy; Vadim Y Arshavsky; Candice S Klug; Wayne L Hubbell; Vsevolod V Gurevich
Structure and function of the visual arrestin oligomer.
The EMBO journal 2007;26(6):1726-36.
2006: Damon Scoville; John D Stamm; Dora Toledo-Warshaviak; Christian Altenbach; Martin Phillips; Alexander Shvetsov; Peter A Rubenstein; Wayne L Hubbell; Emil Reisler
Hydrophobic loop dynamics and actin filament stability.
Biochemistry 2006;45(45):13576-84.
2006: Ned Van Eps; William M Oldham; Heidi E Hamm; Wayne L Hubbell
Structural and dynamical changes in an alpha-subunit of a heterotrimeric G protein along the activation pathway.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16194-9.
2006: William M Oldham; Ned Van Eps; Anita M Preininger; Wayne L Hubbell; Heidi E Hamm
Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins.
Nature structural & molecular biology 2006;13(9):772-7.
2006: Kerstin Jacobsen; Wayne L Hubbell; Oliver P Ernst; Thomas Risse
Details of the partial unfolding of T4 lysozyme on quartz using site-directed spin labeling.
Angewandte Chemie (International ed. in English) 2006;45(23):3874-7.
2006: Alexander Shvetsov; John D Stamm; Martin Phillips; Dora Warshaviak; Christian Altenbach; Peter A Rubenstein; Kálmán Hideg; Wayne L Hubbell; Emil Reisler
Conformational dynamics of loop 262-274 in G- and F-actin.
Biochemistry 2006;45(20):6541-9.
2006: Ana Karin Kusnetzow; Christian Altenbach; Wayne L Hubbell
Conformational states and dynamics of rhodopsin in micelles and bilayers.
Biochemistry 2006;45(17):5538-50.
2006: Susan M Hanson; Derek J Francis; Sergey A Vishnivetskiy; Elena A Kolobova; Wayne L Hubbell; Candice S Klug; Vsevolod V Gurevich
Differential interaction of spin-labeled arrestin with inactive and active phosphorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(13):4900-5.
2006: Qi Cai; Ana Karin Kusnetzow; Wayne L Hubbell; Ian S Haworth; Gian Paola C Gacho; Ned Van Eps; Kálmán Hideg; Eric J Chambers; Peter Z Qin
Site-directed spin labeling measurements of nanometer distances in nucleic acids using a sequence-independent nitroxide probe.
Nucleic acids research 2006;34(17):4722-30.
2005: Janusz Pyka; Jan Ilnicki; Christian Altenbach; Wayne L Hubbell; Wojciech Froncisz
Accessibility and dynamics of nitroxide side chains in T4 lysozyme measured by saturation recovery EPR.
Biophysical journal 2005;89(3):2059-68.
2005: Christian Altenbach; Wojciech Froncisz; Roy Hemker; Hassane S McHaourab; Wayne L Hubbell
Accessibility of nitroxide side chains: absolute Heisenberg exchange rates from power saturation EPR.
Biophysical journal 2005;89(3):2103-12.
2005: Peter Z Qin; Juli Feigon; Wayne L Hubbell
Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg(2+)-dependent docking of a GAAA tetraloop.
Journal of molecular biology 2005;351(1):1-8.
2005: Kerstin Jacobsen; Shirley Oga; Wayne L Hubbell; Thomas Risse
Determination of the orientation of T4 lysozyme vectorially bound to a planar-supported lipid bilayer using site-directed spin labeling.
Biophysical journal 2005;88(6):4351-65.
2004: Jong-Myoung Kim; Christian Altenbach; Masahiro Kono; Daniel D Oprian; Wayne L Hubbell; H Gobind Khorana
Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12508-13.
2004: J Mario Isas; Ralf Langen; Wayne L Hubbell; Harry T Haigler
Structure and dynamics of a helical hairpin that mediates calcium-dependent membrane binding of annexin B12.
The Journal of biological chemistry 2004;279(31):32492-8.
2004: Linda Columbus; Wayne L Hubbell
Mapping backbone dynamics in solution with site-directed spin labeling: GCN4-58 bZip free and bound to DNA.
Biochemistry 2004;43(23):7273-87.
2004: Michael A Lietzow; Wayne L Hubbell
Motion of spin label side chains in cellular retinol-binding protein: correlation with structure and nearest-neighbor interactions in an antiparallel beta-sheet.
Biochemistry 2004;43(11):3137-51.
2003: Thomas Risse; Wayne L Hubbell; J Mario Isas; Harry T Haigler
Structure and dynamics of annexin 12 bound to a planar lipid bilayer.
Physical review letters 2003;91(18):188101.
2003: Anita M Preininger; Ned Van Eps; Nan-Jun Yu; Martina Medkova; Wayne L Hubbell; Heidi E Hamm
The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.
Biochemistry 2003;42(26):7931-41.
2003: Peter Z Qin; Kálmán Hideg; Juli Feigon; Wayne L Hubbell
Monitoring RNA base structure and dynamics using site-directed spin labeling.
Biochemistry 2003;42(22):6772-83.
2003: Jeffrey H Zhang; Gaoping Xiao; Robert P Gunsalus; Wayne L Hubbell
Phosphorylation triggers domain separation in the DNA binding response regulator NarL.
Biochemistry 2003;42(9):2552-9.
2003: Wayne L Hubbell; Christian Altenbach; Cheryl M Hubbell; H Gobind Khorana
Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking.
Advances in protein chemistry 2003;63():243-90.
2002: Ahmed A Serag; Christian Altenbach; Mari Gingery; Wayne L Hubbell; Todd O Yeates
Arrangement of subunits and ordering of beta-strands in an amyloid sheet.
Nature structural biology 2002;9(10):734-9.
2002: Martina Medkova; Anita M Preininger; Nan-Jun Yu; Wayne L Hubbell; Heidi E Hamm
Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation.
Biochemistry 2002;41(31):9962-72.
2002: Linda Columbus; Wayne L Hubbell
A new spin on protein dynamics.
Trends in biochemical sciences 2002;27(6):288-95.
2002: Alexander N Barnakov; Christian Altenbach; Ludmila A Barnakova; Wayne L Hubbell; Gerald L Hazelbauer
Site-directed spin labeling of a bacterial chemoreceptor reveals a dynamic, loosely packed transmembrane domain.
Protein science : a publication of the Protein Society 2002;11(6):1472-81.
2002: J Mario Isas; Ralf Langen; Harry T Haigler; Wayne L Hubbell
Structure and dynamics of a helical hairpin and loop region in annexin 12: a site-directed spin labeling study.
Biochemistry 2002;41(5):1464-73.
2002: Adrian Gross; Wayne L Hubbell
Identification of protein side chains near the membrane-aqueous interface: a site-directed spin labeling study of KcsA.
Biochemistry 2002;41(4):1123-8.
2002: Mark D Sutton; Angelina Guzzo; Issay Narumi; Michael Costanzo; Christian Altenbach; Ann E Ferentz; Wayne L Hubbell; Graham C Walker
A model for the structure of the Escherichia coli SOS-regulated UmuD2 protein.
DNA repair 2002;1(1):77-93.
2001: Christian Altenbach; Judith Klein-Seetharaman; K Cai; H Gobind Khorana; Wayne L Hubbell
Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 316 in helix 8 and residues in the sequence 60-75, covering the cytoplasmic end of helices TM1 and TM2 and their connection loop CL1.
Biochemistry 2001;40(51):15493-500.
2001: Christian Altenbach; K Cai; Judith Klein-Seetharaman; H Gobind Khorana; Wayne L Hubbell
Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8.
Biochemistry 2001;40(51):15483-92.
2001: Christian Altenbach; KJ Oh; R J Trabanino; Kálmán Hideg; Wayne L Hubbell
Estimation of inter-residue distances in spin labeled proteins at physiological temperatures: experimental strategies and practical limitations.
Biochemistry 2001;40(51):15471-82.
2001: K Cai; Judith Klein-Seetharaman; Christian Altenbach; Wayne L Hubbell; H Gobind Khorana
Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between cysteine pairs engineered in cytoplasmic loops 1, 3, and 4.
Biochemistry 2001;40(42):12479-85.
2001: Judith Klein-Seetharaman; John Hwa; K Cai; Christian Altenbach; Wayne L Hubbell; H Gobind Khorana
Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between Cys316 and engineered cysteines in cytoplasmic loop 1.
Biochemistry 2001;40(42):12472-8.
2001: Ahmed A Serag; Christian Altenbach; Mari Gingery; Wayne L Hubbell; Todd O Yeates
Identification of a subunit interface in transthyretin amyloid fibrils: evidence for self-assembly from oligomeric building blocks.
Biochemistry 2001;40(31):9089-96.
2001: Peter Z Qin; SE Butcher; Juli Feigon; Wayne L Hubbell
Quantitative analysis of the isolated GAAA tetraloop/receptor interaction in solution: a site-directed spin labeling study.
Biochemistry 2001;40(23):6929-36.
2001: Linda Columbus; Tamás Kálai; J Jekö; Kálmán Hideg; Wayne L Hubbell
Molecular motion of spin labeled side chains in alpha-helices: analysis by variation of side chain structure.
Biochemistry 2001;40(13):3828-46.
2000: M Zhao; Tamás Kálai; Kálmán Hideg; Christian Altenbach; Wayne L Hubbell; H Ronald Kaback
Binding of spin-labeled galactosides to the lactose permease of Escherichia coli.
Biochemistry 2000;39(37):11381-8.
2000: Wayne L Hubbell; D S Cafiso; Christian Altenbach
Identifying conformational changes with site-directed spin labeling.
Nature structural biology 2000;7(9):735-9.
2000: Ralf Langen; KJ Oh; Duilio Cascio; Wayne L Hubbell
Crystal structures of spin labeled T4 lysozyme mutants: implications for the interpretation of EPR spectra in terms of structure.
Biochemistry 2000;39(29):8396-405.
2000: R Mollaaghababa; H J Steinhoff; Wayne L Hubbell; H Gobind Khorana
Time-resolved site-directed spin-labeling studies of bacteriorhodopsin: loop-specific conformational changes in M.
Biochemistry 2000;39(5):1120-7.
2000: Vadim Gaponenko; Jack W Howarth; Linda Columbus; GM Gasmi-Seabrook; J Yuan; Wayne L Hubbell; Paul R Rosevear
Protein global fold determination using site-directed spin and isotope labeling.
Protein science : a publication of the Protein Society 2000;9(2):302-9.
2000: KJ Oh; Christian Altenbach; R. John Collier; Wayne L Hubbell
Site-directed spin labeling of proteins. Applications to diphtheria toxin.
Methods in molecular biology (Clifton, N.J.) 2000;145():147-69.
1999: M Zhao; K C Zen; J Hernandez-Borrell; Christian Altenbach; Wayne L Hubbell; H Ronald Kaback
Nitroxide scanning electron paramagnetic resonance of helices IV and V and the intervening loop in the lactose permease of Escherichia coli.
Biochemistry 1999;38(48):15970-7.
1999: Ben J Glasgow; Oktay Gasymov; Adil R Abduragimov; Taleh N Yusifov; Christian Altenbach; Wayne L Hubbell
Side chain mobility and ligand interactions of the G strand of tear lipocalins by site-directed spin labeling.
Biochemistry 1999;38(41):13707-16.
1999: K Cai; Judith Klein-Seetharaman; John Hwa; Wayne L Hubbell; H Gobind Khorana
Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase.
Biochemistry 1999;38(39):12893-8.
1999: KJ Oh; H Zhan; C Cui; Christian Altenbach; Wayne L Hubbell; R. John Collier
Conformation of the diphtheria toxin T domain in membranes: a site-directed spin-labeling study of the TH8 helix and TL5 loop.
Biochemistry 1999;38(32):10336-43.
1999: Adrian Gross; Linda Columbus; Kálmán Hideg; Christian Altenbach; Wayne L Hubbell
Structure of the KcsA potassium channel from Streptomyces lividans: a site-directed spin labeling study of the second transmembrane segment.
Biochemistry 1999;38(32):10324-35.
1999: Christian Altenbach; Judith Klein-Seetharaman; John Hwa; H Gobind Khorana; Wayne L Hubbell
Structural features and light-dependent changes in the sequence 59-75 connecting helices I and II in rhodopsin: a site-directed spin-labeling study.
Biochemistry 1999;38(25):7945-9.
1999: Judith Klein-Seetharaman; John Hwa; K Cai; Christian Altenbach; Wayne L Hubbell; H Gobind Khorana
Single-cysteine substitution mutants at amino acid positions 55-75, the sequence connecting the cytoplasmic ends of helices I and II in rhodopsin: reactivity of the sulfhydryl groups and their derivatives identifies a tertiary structure that changes upon light-activation.
Biochemistry 1999;38(25):7938-44.
1999: Christian Altenbach; K Cai; H Gobind Khorana; Wayne L Hubbell
Structural features and light-dependent changes in the sequence 306-322 extending from helix VII to the palmitoylation sites in rhodopsin: a site-directed spin-labeling study.
Biochemistry 1999;38(25):7931-7.
1999: K Cai; Judith Klein-Seetharaman; David L Farrens; C Zhang; Christian Altenbach; Wayne L Hubbell; H Gobind Khorana
Single-cysteine substitution mutants at amino acid positions 306-321 in rhodopsin, the sequence between the cytoplasmic end of helix VII and the palmitoylation sites: sulfhydryl reactivity and transducin activation reveal a tertiary structure.
Biochemistry 1999;38(25):7925-30.
1999: Ralf Langen; K Cai; Christian Altenbach; H Gobind Khorana; Wayne L Hubbell
Structural features of the C-terminal domain of bovine rhodopsin: a site-directed spin-labeling study.
Biochemistry 1999;38(25):7918-24.
1999: M Zhao; K C Zen; Wayne L Hubbell; H Ronald Kaback
Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli.
Biochemistry 1999;38(23):7407-12.
1999: J P Barnes; Z Liang; Hassane S McHaourab; Jack H Freed; Wayne L Hubbell
A multifrequency electron spin resonance study of T4 lysozyme dynamics.
Biophysical journal 1999;76(6):3298-306.
1999: Jason Sun; John C Voss; Wayne L Hubbell; H Ronald Kaback
Proximity between periplasmic loops in the lactose permease of Escherichia coli as determined by site-directed spin labeling.
Biochemistry 1999;38(10):3100-5.
1999: Hassane S McHaourab; Tamás Kálai; Kálmán Hideg; Wayne L Hubbell
Motion of spin-labeled side chains in T4 lysozyme: effect of side chain structure.
Biochemistry 1999;38(10):2947-55.
1999: L Salwiński; Wayne L Hubbell
Structure in the channel forming domain of colicin E1 bound to membranes: the 402-424 sequence.
Protein science : a publication of the Protein Society 1999;8(3):562-72.
1998: Ralf Langen; J Mario Isas; Wayne L Hubbell; Harry T Haigler
A transmembrane form of annexin XII detected by site-directed spin labeling.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14060-5.
1998: Wayne L Hubbell; Adrian Gross; Ralf Langen; Michael A Lietzow
Recent advances in site-directed spin labeling of proteins.
Current opinion in structural biology 1998;8(5):649-56.
1998: W Piasecki; Wojciech Froncisz; Wayne L Hubbell
A rectangular loop-gap resonator for EPR studies of aqueous samples.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;134(1):36-43.
1998: Ralf Langen; J Mario Isas; Hartmut Luecke; Harry T Haigler; Wayne L Hubbell
Membrane-mediated assembly of annexins studied by site-directed spin labeling.
The Journal of biological chemistry 1998;273(35):22453-7.
1998: Q Wang; John C Voss; Wayne L Hubbell; H Ronald Kaback
Proximity of helices VIII (Ala273) and IX (Met299) in the lactose permease of Escherichia coli.
Biochemistry 1998;37(14):4910-5.
1998: Ben J Glasgow; Adil R Abduragimov; Taleh N Yusifov; Oktay Gasymov; Joseph Horwitz; Wayne L Hubbell; Kym F Faull
A conserved disulfide motif in human tear lipocalins influences ligand binding.
Biochemistry 1998;37(8):2215-25.
1998: John C Voss; Wayne L Hubbell; H Ronald Kaback
Helix packing in the lactose permease determined by metal-nitroxide interaction.
Biochemistry 1998;37(1):211-6.
1997: Jong-Myoung Kim; Christian Altenbach; Robin Thurmond; H Gobind Khorana; Wayne L Hubbell
Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14273-8.
1997: K Cai; Ralf Langen; Wayne L Hubbell; H Gobind Khorana
Structure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14267-72.
1997: John C Voss; Wayne L Hubbell; J Hernandez-Borrell; H Ronald Kaback
Site-directed spin-labeling of transmembrane domain VII and the 4B1 antibody epitope in the lactose permease of Escherichia coli.
Biochemistry 1997;36(49):15055-61.
1997: MM He; John C Voss; Wayne L Hubbell; H Ronald Kaback
Arginine 302 (helix IX) in the lactose permease of Escherichia coli is in close proximity to glutamate 269 (helix VIII) as well as glutamate 325.
Biochemistry 1997;36(44):13682-7.
1997: Hassane S McHaourab; KJ Oh; C J Fang; Wayne L Hubbell
Conformation of T4 lysozyme in solution. Hinge-bending motion and the substrate-induced conformational transition studied by site-directed spin labeling.
Biochemistry 1997;36(2):307-16.
1996: K Yang; David L Farrens; Christian Altenbach; Z T Farahbakhsh; Wayne L Hubbell; H Gobind Khorana
Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels.
Biochemistry 1996;35(45):14040-6.
1996: David L Farrens; Christian Altenbach; K Yang; Wayne L Hubbell; H Gobind Khorana
Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin.
Science (New York, N.Y.) 1996;274(5288):768-70.
1996: John C Voss; M M He; Wayne L Hubbell; H Ronald Kaback
Site-directed spin labeling demonstrates that transmembrane domain XII in the lactose permease of Escherichia coli is an alpha-helix.
Biochemistry 1996;35(39):12915-8.
1996: Christian Altenbach; K Yang; David L Farrens; Z T Farahbakhsh; H Gobind Khorana; Wayne L Hubbell
Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study.
Biochemistry 1996;35(38):12470-8.
1996: K Yang; David L Farrens; Wayne L Hubbell; H Gobind Khorana
Structure and function in rhodopsin. Single cysteine substitution mutants in the cytoplasmic interhelical E-F loop region show position-specific effects in transducin activation.
Biochemistry 1996;35(38):12464-9.
1996: Jian Wu; John C Voss; Wayne L Hubbell; H Ronald Kaback
Site-directed spin labeling and chemical crosslinking demonstrate that helix V is close to helices VII and VIII in the lactose permease of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10123-7.
1996: KJ Oh; H Zhan; C Cui; Kálmán Hideg; R. John Collier; Wayne L Hubbell
Organization of diphtheria toxin T domain in bilayers: a site-directed spin labeling study.
Science (New York, N.Y.) 1996;273(5276):810-2.
1996: Wayne L Hubbell; Hassane S McHaourab; Christian Altenbach; M A Lietzow
Watching proteins move using site-directed spin labeling.
Structure (London, England : 1993) 1996;4(7):779-83.
1996: Hassane S McHaourab; M A Lietzow; Kálmán Hideg; Wayne L Hubbell
Motion of spin-labeled side chains in T4 lysozyme. Correlation with protein structure and dynamics.
Biochemistry 1996;35(24):7692-704.
1996: M Wiedau-Pazos; J R Trudell; Christian Altenbach; D J Kane; Wayne L Hubbell; Dale E Bredesen
Expression of bcl-2 inhibits cellular radical generation.
Free radical research 1996;24(3):205-12.
1995: John C Voss; Wayne L Hubbell; H Ronald Kaback
Distance determination in proteins using designed metal ion binding sites and site-directed spin labeling: application to the lactose permease of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12300-3.
1995: John C Voss; L Salwiński; H Ronald Kaback; Wayne L Hubbell
A method for distance determination in proteins using a designed metal ion binding site and site-directed spin labeling: evaluation with T4 lysozyme.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12295-9.
1995: M M He; John C Voss; Wayne L Hubbell; H Ronald Kaback
Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 2. Proximity of helix IX (Arg302) with helix X (His322 and Glu325).
Biochemistry 1995;34(48):15667-70.
1995: M M He; John C Voss; Wayne L Hubbell; H Ronald Kaback
Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 1. Proximity of helix VII (Asp237 and Asp240) with helices X (Lys319) and XI (Lys358).
Biochemistry 1995;34(48):15661-6.
1995: M L Ujwal; H Jung; E Bibi; C Manoil; Christian Altenbach; Wayne L Hubbell; H Ronald Kaback
Membrane topology of helices VII and XI in the lactose permease of Escherichia coli studied by lacY-phoA fusion analysis and site-directed spectroscopy.
Biochemistry 1995;34(45):14909-17.
1995: Heinz-Jürgen Steinhoff; R Mollaaghababa; Christian Altenbach; H Gobind Khorana; Wayne L Hubbell
Site directed spin labeling studies of structure and dynamics in bacteriorhodopsin.
Biophysical chemistry 1995;56(1-2):89-94.
1995: Z T Farahbakhsh; Kevin D Ridge; H Gobind Khorana; Wayne L Hubbell
Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study.
Biochemistry 1995;34(27):8812-9.
1995: K Jung; John C Voss; M He; Wayne L Hubbell; H Ronald Kaback
Engineering a metal binding site within a polytopic membrane protein, the lactose permease of Escherichia coli.
Biochemistry 1995;34(19):6272-7.
1995: Ben J Glasgow; Adil R Abduragimov; Z T Farahbakhsh; Kym F Faull; Wayne L Hubbell
Tear lipocalins bind a broad array of lipid ligands.
Current eye research 1995;14(5):363-72.
1995: H Zhan; KJ Oh; Y K Shin; Wayne L Hubbell; R. John Collier
Interaction of the isolated transmembrane domain of diphtheria toxin with membranes.
Biochemistry 1995;34(14):4856-63.
1995: Z T Farahbakhsh; Qing Ling Huang; Lin Lin Ding; Christian Altenbach; Heinz-Jürgen Steinhoff; Joseph Horwitz; Wayne L Hubbell
Interaction of alpha-crystallin with spin-labeled peptides.
Biochemistry 1995;34(2):509-16.
1994: Heinz-Jürgen Steinhoff; R Mollaaghababa; Christian Altenbach; Kálmán Hideg; M Krebs; H Gobind Khorana; Wayne L Hubbell
Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin.
Science (New York, N.Y.) 1994;266(5182):105-7.
1994: V W Cornish; D R Benson; Christian Altenbach; K Hideg; Wayne L Hubbell; Peter G Schultz
Site-specific incorporation of biophysical probes into proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):2910-4.
1994: Christian Altenbach; D A Greenhalgh; H Gobind Khorana; Wayne L Hubbell
A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1667-71.
1993: Z T Farahbakhsh; K Hideg; Wayne L Hubbell
Photoactivated conformational changes in rhodopsin: a time-resolved spin label study.
Science (New York, N.Y.) 1993;262(5138):1416-9.
1993: J F Resek; Z T Farahbakhsh; Wayne L Hubbell; H Gobind Khorana
Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin.
Biochemistry 1993;32(45):12025-32.
1993: E Perozo; Wayne L Hubbell
Voltage activation of reconstituted sodium channels: use of bacteriorhodopsin as a light-driven current source.
Biochemistry 1993;32(39):10471-8.
1993: Y K Shin; C Levinthal; F Levinthal; Wayne L Hubbell
Colicin E1 binding to membranes: time-resolved studies of spin-labeled mutants.
Science (New York, N.Y.) 1993;259(5097):960-3.
1993: G Wu; Wayne L Hubbell
Phospholipid asymmetry and transmembrane diffusion in photoreceptor disc membranes.
Biochemistry 1993;32(3):879-88.
1992: Z T Farahbakhsh; Christian Altenbach; Wayne L Hubbell
Spin labeled cysteines as sensors for protein-lipid interaction and conformation in rhodopsin.
Photochemistry and photobiology 1992;56(6):1019-33.
1992: Y K Shin; Wayne L Hubbell
Determination of electrostatic potentials at biological interfaces using electron-electron double resonance.
Biophysical journal 1992;61(6):1443-53.
1992: S J Anthony-Cahill; P A Benfield; R Fairman; Zelda R Wasserman; S L Brenner; W F Stafford; Christian Altenbach; Wayne L Hubbell; W F DeGrado
Molecular characterization of helix-loop-helix peptides.
Science (New York, N.Y.) 1992;255(5047):979-83.
1991: D A Greenhalgh; Christian Altenbach; Wayne L Hubbell; H Gobind Khorana
Locations of Arg-82, Asp-85, and Asp-96 in helix C of bacteriorhodopsin relative to the aqueous boundaries.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8626-30.
1991: F Levinthal; A P Todd; Wayne L Hubbell; C Levinthal
A single tryptic fragment of colicin E1 can form an ion channel: stoichiometry confirms kinetics.
Proteins 1991;11(4):254-62.
1990: Magdalena T Tosteson; O Alvarez; Wayne L Hubbell; R M Bieganski; C Attenbach; L H Caporales; J J Levy; R F Nutt; M Rosenblatt; D C Tosteson
Primary structure of peptides and ion channels. Role of amino acid side chains in voltage gating of melittin channels.
Biophysical journal 1990;58(6):1367-75.
1990: K R Oldenburg; Wayne L Hubbell
Invertebrate rhodopsin cleavage by an endogenous calcium activated protease.
Experimental eye research 1990;51(4):463-72.
1990: Christian Altenbach; T Marti; H Gobind Khorana; Wayne L Hubbell
Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants.
Science (New York, N.Y.) 1990;248(4959):1088-92.
1990: Wayne L Hubbell
Transbilayer coupling mechanism for the formation of lipid asymmetry in biological membranes. Application to the photoreceptor disc membrane.
Biophysical journal 1990;57(1):99-108.
1990: F C Tsui; S A Sundberg; Wayne L Hubbell
Distribution of charge on photoreceptor disc membranes and implications for charged lipid asymmetry.
Biophysical journal 1990;57(1):85-97.
1989: Christian Altenbach; W Froncisz; J S Hyde; Wayne L Hubbell
Conformation of spin-labeled melittin at membrane surfaces investigated by pulse saturation recovery and continuous wave power saturation electron paramagnetic resonance.
Biophysical journal 1989;56(6):1183-91.
1989: Christian Altenbach; S L Flitsch; H Gobind Khorana; Wayne L Hubbell
Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines.
Biochemistry 1989;28(19):7806-12.
1989: A P Todd; J Cong; F Levinthal; C Levinthal; Wayne L Hubbell
Site-directed mutagenesis of colicin E1 provides specific attachment sites for spin labels whose spectra are sensitive to local conformation.
Proteins 1989;6(3):294-305.
1988: Christian Altenbach; Wayne L Hubbell
The aggregation state of spin-labeled melittin in solution and bound to phospholipid membranes: evidence that membrane-bound melittin is monomeric.
Proteins 1988;3(4):230-42.