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Wayne Hubbell

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Procedures

Electron Spin Resonance Spectroscopy

Chemicals & Drugs

Concepts & Ideas

Physiology

Site-Directed Mutagenesis

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Amino Acid Sequence

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Co-Publications
Name
51
Altenbach, Christian
27
Khorana, Gobind
17
Kaback, Ronald
13
Hideg, Kálmán
12
Voss, J
10
Cai, K
8
Klein-Seetharaman, Judith
8
Langen, Ralf
8
Van Eps, Ned
7
Oh, KJ
6
McHaourab, Hassane
5
Columbus, Linda
5
Farrens, David
5
Isas, Mario
5
Haigler, Harry

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Publications

TOP 3
López Carlos J; Fleissner Mark R; Guo Zhefeng; Kusnetzow Ana K; Hubbell Wayne L
Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins.
Fleissner Mark R; Cascio Duilio; Hubbell Wayne L
Structural origin of weakly ordered nitroxide motion in spin-labeled proteins.
Scoville Damon; Stamm John D; Altenbach Christian; Shvetsov Alexander; Kokabi Kaveh; Rubenstein Peter A; Hubbell Wayne L; Reisler Emil
Effects of binding factors on structural elements in F-actin.

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All Publications

2009: López Carlos J; Fleissner Mark R; Guo Zhefeng; Kusnetzow Ana K; Hubbell Wayne L
Osmolyte perturbation reveals conformational equilibria in spin-labeled proteins.
Protein science : a publication of the Protein Society 2009;18(8):1637-52.
2009: Fleissner Mark R; Cascio Duilio; Hubbell Wayne L
Structural origin of weakly ordered nitroxide motion in spin-labeled proteins.
Protein science : a publication of the Protein Society 2009;18(5):893-908.
2009: Scoville Damon; Stamm John D; Altenbach Christian; Shvetsov Alexander; Kokabi Kaveh; Rubenstein Peter A; Hubbell Wayne L; Reisler Emil
Effects of binding factors on structural elements in F-actin.
Biochemistry 2009;48(2):370-8.
2008: Hanson Susan M; Dawson Eric S; Francis Derek J; Van Eps Ned; Klug Candice S; Hubbell Wayne L; Meiler Jens; Gurevich Vsevolod V
A model for the solution structure of the rod arrestin tetramer.
Structure (London, England : 1993) 2008;16(6):924-34.
2008: Altenbach Christian; Kusnetzow Ana Karin; Ernst Oliver P; Hofmann Klaus Peter; Hubbell Wayne L
High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(21):7439-44.
2008: Guo Zhefeng; Cascio Duilio; Hideg Kálmán; Hubbell Wayne L
Structural determinants of nitroxide motion in spin-labeled proteins: solvent-exposed sites in helix B of T4 lysozyme.
Protein science : a publication of the Protein Society 2008;17(2):228-39.
2008: Hanson Susan M; Vishnivetskiy Sergey A; Hubbell Wayne L; Gurevich Vsevolod V
Opposing effects of inositol hexakisphosphate on rod arrestin and arrestin2 self-association.
Biochemistry 2008;47(3):1070-5.
2007: Smirnova Irina; Kasho Vladimir; Choe Jun-Yong; Altenbach Christian; Hubbell Wayne L; Kaback H Ronald
Sugar binding induces an outward facing conformation of LacY.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(42):16504-9.
2007: Guo Zhefeng; Cascio Duilio; Hideg Kálmán; Kálái Támás; Hubbell Wayne L
Structural determinants of nitroxide motion in spin-labeled proteins: tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein science : a publication of the Protein Society 2007;16(6):1069-86.
2007: Sasaki Jun; Phillips Brian J; Chen Xinpu; Van Eps Ned; Tsai Ah-Lim; Hubbell Wayne L; Spudich John L
Different dark conformations function in color-sensitive photosignaling by the sensory rhodopsin I-HtrI complex.
Biophysical journal 2007;92(11):4045-53.
2007: Oldham William M; Van Eps Ned; Preininger Anita M; Hubbell Wayne L; Hamm Heidi E
Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):7927-32.
2007: Hanson Susan M; Van Eps Ned; Francis Derek J; Altenbach Christian; Vishnivetskiy Sergey A; Arshavsky Vadim Y; Klug Candice S; Hubbell Wayne L; Gurevich Vsevolod V
Structure and function of the visual arrestin oligomer.
The EMBO journal 2007;26(6):1726-36.
2006: Scoville Damon; Stamm John D; Toledo-Warshaviak Dora; Altenbach Christian; Phillips Martin; Shvetsov Alexander; Rubenstein Peter A; Hubbell Wayne L; Reisler Emil
Hydrophobic loop dynamics and actin filament stability.
Biochemistry 2006;45(45):13576-84.
2006: Van Eps Ned; Oldham William M; Hamm Heidi E; Hubbell Wayne L
Structural and dynamical changes in an alpha-subunit of a heterotrimeric G protein along the activation pathway.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16194-9.
2006: Oldham William M; Van Eps Ned; Preininger Anita M; Hubbell Wayne L; Hamm Heidi E
Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins.
Nature structural & molecular biology 2006;13(9):772-7.
2006: Jacobsen Kerstin; Hubbell Wayne L; Ernst Oliver P; Risse Thomas
Details of the partial unfolding of T4 lysozyme on quartz using site-directed spin labeling.
Angewandte Chemie (International ed. in English) 2006;45(23):3874-7.
2006: Shvetsov Alexander; Stamm John D; Phillips Martin; Warshaviak Dora; Altenbach Christian; Rubenstein Peter A; Hideg Kálmán; Hubbell Wayne L; Reisler Emil
Conformational dynamics of loop 262-274 in G- and F-actin.
Biochemistry 2006;45(20):6541-9.
2006: Kusnetzow Ana Karin; Altenbach Christian; Hubbell Wayne L
Conformational states and dynamics of rhodopsin in micelles and bilayers.
Biochemistry 2006;45(17):5538-50.
2006: Hanson Susan M; Francis Derek J; Vishnivetskiy Sergey A; Kolobova Elena A; Hubbell Wayne L; Klug Candice S; Gurevich Vsevolod V
Differential interaction of spin-labeled arrestin with inactive and active phosphorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(13):4900-5.
2006: Cai Qi; Kusnetzow Ana Karin; Hubbell Wayne L; Haworth Ian S; Gacho Gian Paola C; Van Eps Ned; Hideg Kálmán; Chambers Eric J; Qin Peter Z
Site-directed spin labeling measurements of nanometer distances in nucleic acids using a sequence-independent nitroxide probe.
Nucleic acids research 2006;34(17):4722-30.
2005: Pyka Janusz; Ilnicki Jan; Altenbach Christian; Hubbell Wayne L; Froncisz Wojciech
Accessibility and dynamics of nitroxide side chains in T4 lysozyme measured by saturation recovery EPR.
Biophysical journal 2005;89(3):2059-68.
2005: Altenbach Christian; Froncisz Wojciech; Hemker Roy; McHaourab Hassane; Hubbell Wayne L
Accessibility of nitroxide side chains: absolute Heisenberg exchange rates from power saturation EPR.
Biophysical journal 2005;89(3):2103-12.
2005: Qin Peter Z; Feigon Juli; Hubbell Wayne L
Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg(2+)-dependent docking of a GAAA tetraloop.
Journal of molecular biology 2005;351(1):1-8.
2005: Jacobsen Kerstin; Oga Shirley; Hubbell Wayne L; Risse Thomas
Determination of the orientation of T4 lysozyme vectorially bound to a planar-supported lipid bilayer using site-directed spin labeling.
Biophysical journal 2005;88(6):4351-65.
2004: Kim Jong-Myoung; Altenbach Christian; Kono Masahiro; Oprian Daniel D; Hubbell Wayne L; Khorana H Gobind
Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12508-13.
2004: Isas J Mario; Langen Ralf; Hubbell Wayne L; Haigler Harry T
Structure and dynamics of a helical hairpin that mediates calcium-dependent membrane binding of annexin B12.
The Journal of biological chemistry 2004;279(31):32492-8.
2004: Columbus Linda; Hubbell Wayne L
Mapping backbone dynamics in solution with site-directed spin labeling: GCN4-58 bZip free and bound to DNA.
Biochemistry 2004;43(23):7273-87.
2004: Lietzow Michael A; Hubbell Wayne L
Motion of spin label side chains in cellular retinol-binding protein: correlation with structure and nearest-neighbor interactions in an antiparallel beta-sheet.
Biochemistry 2004;43(11):3137-51.
2003: Risse T; Hubbell W L; Isas J M; Haigler H T
Structure and dynamics of annexin 12 bound to a planar lipid bilayer.
Physical review letters 2003;91(18):188101.
2003: Preininger Anita M; Van Eps Ned; Yu Nan-Jun; Medkova Martina; Hubbell Wayne L; Hamm Heidi E
The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.
Biochemistry 2003;42(26):7931-41.
2003: Qin Peter Z; Hideg Kálmán; Feigon Juli; Hubbell Wayne L
Monitoring RNA base structure and dynamics using site-directed spin labeling.
Biochemistry 2003;42(22):6772-83.
2003: Zhang Jeffrey H; Xiao Gaoping; Gunsalus Robert P; Hubbell Wayne L
Phosphorylation triggers domain separation in the DNA binding response regulator NarL.
Biochemistry 2003;42(9):2552-9.
2003: Hubbell Wayne L; Altenbach Christian; Hubbell Cheryl M; Khorana H Gobind
Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking.
Advances in protein chemistry 2003;63():243-90.
2002: Serag Ahmed A; Altenbach Christian; Gingery Mari; Hubbell Wayne L; Yeates Todd O
Arrangement of subunits and ordering of beta-strands in an amyloid sheet.
Nature structural biology 2002;9(10):734-9.
2002: Medkova Martina; Preininger Anita M; Yu Nan-Jun; Hubbell Wayne L; Hamm Heidi E
Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation.
Biochemistry 2002;41(31):9962-72.
2002: Columbus Linda; Hubbell Wayne L
A new spin on protein dynamics.
Trends in biochemical sciences 2002;27(6):288-95.
2002: Barnakov Alexander; Altenbach Christian; Barnakova Ludmila; Hubbell Wayne L; Hazelbauer Gerald L
Site-directed spin labeling of a bacterial chemoreceptor reveals a dynamic, loosely packed transmembrane domain.
Protein science : a publication of the Protein Society 2002;11(6):1472-81.
2002: Isas J Mario; Langen Ralf; Haigler Harry T; Hubbell Wayne L
Structure and dynamics of a helical hairpin and loop region in annexin 12: a site-directed spin labeling study.
Biochemistry 2002;41(5):1464-73.
2002: Sutton Mark D; Guzzo Angelina; Narumi Issay; Costanzo Michael; Altenbach Christian; Ferentz Ann E; Hubbell Wayne L; Walker Graham C
A model for the structure of the Escherichia coli SOS-regulated UmuD2 protein.
DNA repair 2002;1(1):77-93.
2002: Gross Adrian; Hubbell Wayne L
Identification of protein side chains near the membrane-aqueous interface: a site-directed spin labeling study of KcsA.
Biochemistry 2002;41(4):1123-8.
2001: Altenbach C; Klein-Seetharaman J; Cai K; Khorana H G; Hubbell W L
Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 316 in helix 8 and residues in the sequence 60-75, covering the cytoplasmic end of helices TM1 and TM2 and their connection loop CL1.
Biochemistry 2001;40(51):15493-500.
2001: Altenbach C; Cai K; Klein-Seetharaman J; Khorana H G; Hubbell W L
Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8.
Biochemistry 2001;40(51):15483-92.
2001: Altenbach C; Oh K J; Trabanino R J; Hideg K; Hubbell W L
Estimation of inter-residue distances in spin labeled proteins at physiological temperatures: experimental strategies and practical limitations.
Biochemistry 2001;40(51):15471-82.
2001: Cai K; Klein-Seetharaman J; Altenbach C; Hubbell W L; Khorana H G
Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between cysteine pairs engineered in cytoplasmic loops 1, 3, and 4.
Biochemistry 2001;40(42):12479-85.
2001: Klein-Seetharaman J; Hwa J; Cai K; Altenbach C; Hubbell W L; Khorana H G
Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between Cys316 and engineered cysteines in cytoplasmic loop 1.
Biochemistry 2001;40(42):12472-8.
2001: Serag A A; Altenbach C; Gingery M; Hubbell W L; Yeates T O
Identification of a subunit interface in transthyretin amyloid fibrils: evidence for self-assembly from oligomeric building blocks.
Biochemistry 2001;40(31):9089-96.
2001: Qin P Z; Butcher S E; Feigon J; Hubbell W L
Quantitative analysis of the isolated GAAA tetraloop/receptor interaction in solution: a site-directed spin labeling study.
Biochemistry 2001;40(23):6929-36.
2001: Columbus L; Kálai T; Jekö J; Hideg K; Hubbell W L
Molecular motion of spin labeled side chains in alpha-helices: analysis by variation of side chain structure.
Biochemistry 2001;40(13):3828-46.
2000: Zhao M; Kálai T; Hideg K; Altenbach C; Hubbell W L; Kaback H R
Binding of spin-labeled galactosides to the lactose permease of Escherichia coli.
Biochemistry 2000;39(37):11381-8.
2000: Hubbell W L; Cafiso D S; Altenbach C
Identifying conformational changes with site-directed spin labeling.
Nature structural biology 2000;7(9):735-9.
2000: Langen R; Oh K J; Cascio D; Hubbell W L
Crystal structures of spin labeled T4 lysozyme mutants: implications for the interpretation of EPR spectra in terms of structure.
Biochemistry 2000;39(29):8396-405.
2000: Gaponenko V; Howarth J W; Columbus L; Gasmi-Seabrook G; Yuan J; Hubbell W L; Rosevear P R
Protein global fold determination using site-directed spin and isotope labeling.
Protein science : a publication of the Protein Society 2000;9(2):302-9.
2000: Mollaaghababa R; Steinhoff H J; Hubbell W L; Khorana H G
Time-resolved site-directed spin-labeling studies of bacteriorhodopsin: loop-specific conformational changes in M.
Biochemistry 2000;39(5):1120-7.
2000: Oh K J; Altenbach C; Collier R J; Hubbell W L
Site-directed spin labeling of proteins. Applications to diphtheria toxin.
Methods in molecular biology (Clifton, N.J.) 2000;145():147-69.
1999: Zhao M; Zen K C; Hernandez-Borrell J; Altenbach C; Hubbell W L; Kaback H R
Nitroxide scanning electron paramagnetic resonance of helices IV and V and the intervening loop in the lactose permease of Escherichia coli.
Biochemistry 1999;38(48):15970-7.
1999: Glasgow B J; Gasymov O K; Abduragimov A R; Yusifov T N; Altenbach C; Hubbell W L
Side chain mobility and ligand interactions of the G strand of tear lipocalins by site-directed spin labeling.
Biochemistry 1999;38(41):13707-16.
1999: Cai K; Klein-Seetharaman J; Hwa J; Hubbell W L; Khorana H G
Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase.
Biochemistry 1999;38(39):12893-8.
1999: Oh K J; Zhan H; Cui C; Altenbach C; Hubbell W L; Collier R J
Conformation of the diphtheria toxin T domain in membranes: a site-directed spin-labeling study of the TH8 helix and TL5 loop.
Biochemistry 1999;38(32):10336-43.
1999: Gross A; Columbus L; Hideg K; Altenbach C; Hubbell W L
Structure of the KcsA potassium channel from Streptomyces lividans: a site-directed spin labeling study of the second transmembrane segment.
Biochemistry 1999;38(32):10324-35.
1999: Altenbach C; Klein-Seetharaman J; Hwa J; Khorana H G; Hubbell W L
Structural features and light-dependent changes in the sequence 59-75 connecting helices I and II in rhodopsin: a site-directed spin-labeling study.
Biochemistry 1999;38(25):7945-9.
1999: Klein-Seetharaman J; Hwa J; Cai K; Altenbach C; Hubbell W L; Khorana H G
Single-cysteine substitution mutants at amino acid positions 55-75, the sequence connecting the cytoplasmic ends of helices I and II in rhodopsin: reactivity of the sulfhydryl groups and their derivatives identifies a tertiary structure that changes upon light-activation.
Biochemistry 1999;38(25):7938-44.
1999: Altenbach C; Cai K; Khorana H G; Hubbell W L
Structural features and light-dependent changes in the sequence 306-322 extending from helix VII to the palmitoylation sites in rhodopsin: a site-directed spin-labeling study.
Biochemistry 1999;38(25):7931-7.
1999: Cai K; Klein-Seetharaman J; Farrens D; Zhang C; Altenbach C; Hubbell W L; Khorana H G
Single-cysteine substitution mutants at amino acid positions 306-321 in rhodopsin, the sequence between the cytoplasmic end of helix VII and the palmitoylation sites: sulfhydryl reactivity and transducin activation reveal a tertiary structure.
Biochemistry 1999;38(25):7925-30.
1999: Langen R; Cai K; Altenbach C; Khorana H G; Hubbell W L
Structural features of the C-terminal domain of bovine rhodopsin: a site-directed spin-labeling study.
Biochemistry 1999;38(25):7918-24.
1999: Zhao M; Zen K C; Hubbell W L; Kaback H R
Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli.
Biochemistry 1999;38(23):7407-12.
1999: Barnes J P; Liang Z; Mchaourab H S; Freed J H; Hubbell W L
A multifrequency electron spin resonance study of T4 lysozyme dynamics.
Biophysical journal 1999;76(6):3298-306.
1999: Salwinski L; Hubbell W L
Structure in the channel forming domain of colicin E1 bound to membranes: the 402-424 sequence.
Protein science : a publication of the Protein Society 1999;8(3):562-72.
1999: Sun J; Voss J; Hubbell W L; Kaback H R
Proximity between periplasmic loops in the lactose permease of Escherichia coli as determined by site-directed spin labeling.
Biochemistry 1999;38(10):3100-5.
1999: Mchaourab H S; Kálai T; Hideg K; Hubbell W L
Motion of spin-labeled side chains in T4 lysozyme: effect of side chain structure.
Biochemistry 1999;38(10):2947-55.
1998: Langen R; Isas J M; Hubbell W L; Haigler H T
A transmembrane form of annexin XII detected by site-directed spin labeling.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14060-5.
1998: Hubbell W L; Gross A; Langen R; Lietzow M A
Recent advances in site-directed spin labeling of proteins.
Current opinion in structural biology 1998;8(5):649-56.
1998: Piasecki W; Froncisz W; Hubbell W L
A rectangular loop-gap resonator for EPR studies of aqueous samples.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1998;134(1):36-43.
1998: Langen R; Isas J M; Luecke H; Haigler H T; Hubbell W L
Membrane-mediated assembly of annexins studied by site-directed spin labeling.
The Journal of biological chemistry 1998;273(35):22453-7.
1998: Wang Q; Voss J; Hubbell W L; Kaback H R
Proximity of helices VIII (Ala273) and IX (Met299) in the lactose permease of Escherichia coli.
Biochemistry 1998;37(14):4910-5.
1998: Glasgow B J; Abduragimov A R; Yusifov T N; Gasymov O K; Horwitz J; Hubbell W L; Faull K F
A conserved disulfide motif in human tear lipocalins influences ligand binding.
Biochemistry 1998;37(8):2215-25.
1998: Voss J; Hubbell W L; Kaback H R
Helix packing in the lactose permease determined by metal-nitroxide interaction.
Biochemistry 1998;37(1):211-6.
1997: Kim J M; Altenbach C; Thurmond R L; Khorana H G; Hubbell W L
Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14273-8.
1997: Cai K; Langen R; Hubbell W L; Khorana H G
Structure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14267-72.
1997: Voss J; Hubbell W L; Hernandez-Borrell J; Kaback H R
Site-directed spin-labeling of transmembrane domain VII and the 4B1 antibody epitope in the lactose permease of Escherichia coli.
Biochemistry 1997;36(49):15055-61.
1997: He M M; Voss J; Hubbell W L; Kaback H R
Arginine 302 (helix IX) in the lactose permease of Escherichia coli is in close proximity to glutamate 269 (helix VIII) as well as glutamate 325.
Biochemistry 1997;36(44):13682-7.
1997: Mchaourab H S; Oh K J; Fang C J; Hubbell W L
Conformation of T4 lysozyme in solution. Hinge-bending motion and the substrate-induced conformational transition studied by site-directed spin labeling.
Biochemistry 1997;36(2):307-16.
1996: Yang K; Farrens D L; Altenbach C; Farahbakhsh Z T; Hubbell W L; Khorana H G
Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels.
Biochemistry 1996;35(45):14040-6.
1996: Farrens D L; Altenbach C; Yang K; Hubbell W L; Khorana H G
Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin.
Science (New York, N.Y.) 1996;274(5288):768-70.
1996: Voss J; He M M; Hubbell W L; Kaback H R
Site-directed spin labeling demonstrates that transmembrane domain XII in the lactose permease of Escherichia coli is an alpha-helix.
Biochemistry 1996;35(39):12915-8.
1996: Altenbach C; Yang K; Farrens D L; Farahbakhsh Z T; Khorana H G; Hubbell W L
Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study.
Biochemistry 1996;35(38):12470-8.
1996: Yang K; Farrens D L; Hubbell W L; Khorana H G
Structure and function in rhodopsin. Single cysteine substitution mutants in the cytoplasmic interhelical E-F loop region show position-specific effects in transducin activation.
Biochemistry 1996;35(38):12464-9.
1996: Wu J; Voss J; Hubbell W L; Kaback H R
Site-directed spin labeling and chemical crosslinking demonstrate that helix V is close to helices VII and VIII in the lactose permease of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10123-7.
1996: Oh K J; Zhan H; Cui C; Hideg K; Collier R J; Hubbell W L
Organization of diphtheria toxin T domain in bilayers: a site-directed spin labeling study.
Science (New York, N.Y.) 1996;273(5276):810-2.
1996: Hubbell W L; Mchaourab H S; Altenbach C; Lietzow M A
Watching proteins move using site-directed spin labeling.
Structure (London, England : 1993) 1996;4(7):779-83.
1996: Mchaourab H S; Lietzow M A; Hideg K; Hubbell W L
Motion of spin-labeled side chains in T4 lysozyme. Correlation with protein structure and dynamics.
Biochemistry 1996;35(24):7692-704.
1996: Wiedau-Pazos M; Trudell J R; Altenbach C; Kane D J; Hubbell W L; Bredesen D E
Expression of bcl-2 inhibits cellular radical generation.
Free radical research 1996;24(3):205-12.
1995: Voss J; Hubbell W L; Kaback H R
Distance determination in proteins using designed metal ion binding sites and site-directed spin labeling: application to the lactose permease of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12300-3.
1995: Voss J; Salwinski L; Kaback H R; Hubbell W L
A method for distance determination in proteins using a designed metal ion binding site and site-directed spin labeling: evaluation with T4 lysozyme.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12295-9.
1995: He M M; Voss J; Hubbell W L; Kaback H R
Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 2. Proximity of helix IX (Arg302) with helix X (His322 and Glu325).
Biochemistry 1995;34(48):15667-70.
1995: He M M; Voss J; Hubbell W L; Kaback H R
Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 1. Proximity of helix VII (Asp237 and Asp240) with helices X (Lys319) and XI (Lys358).
Biochemistry 1995;34(48):15661-6.
1995: Ujwal M L; Jung H; Bibi E; Manoil C; Altenbach C; Hubbell W L; Kaback H R
Membrane topology of helices VII and XI in the lactose permease of Escherichia coli studied by lacY-phoA fusion analysis and site-directed spectroscopy.
Biochemistry 1995;34(45):14909-17.
1995: Steinhoff H J; Mollaaghababa R; Altenbach C; Khorana H G; Hubbell W L
Site directed spin labeling studies of structure and dynamics in bacteriorhodopsin.
Biophysical chemistry 1995;56(1-2):89-94.
1995: Farahbakhsh Z T; Ridge K D; Khorana H G; Hubbell W L
Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study.
Biochemistry 1995;34(27):8812-9.
1995: Jung K; Voss J; He M; Hubbell W L; Kaback H R
Engineering a metal binding site within a polytopic membrane protein, the lactose permease of Escherichia coli.
Biochemistry 1995;34(19):6272-7.
1995: Glasgow B J; Abduragimov A R; Farahbakhsh Z T; Faull K F; Hubbell W L
Tear lipocalins bind a broad array of lipid ligands.
Current eye research 1995;14(5):363-72.
1995: Zhan H; Oh K J; Shin Y K; Hubbell W L; Collier R J
Interaction of the isolated transmembrane domain of diphtheria toxin with membranes.
Biochemistry 1995;34(14):4856-63.
1995: Farahbakhsh Z T; Huang Q L; Ding L L; Altenbach C; Steinhoff H J; Horwitz J; Hubbell W L
Interaction of alpha-crystallin with spin-labeled peptides.
Biochemistry 1995;34(2):509-16.
1994: Steinhoff H J; Mollaaghababa R; Altenbach C; Hideg K; Krebs M; Khorana H G; Hubbell W L
Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin.
Science (New York, N.Y.) 1994;266(5182):105-7.
1994: Cornish V W; Benson D R; Altenbach C A; Hideg K; Hubbell W L; Schultz P G
Site-specific incorporation of biophysical probes into proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):2910-4.
1994: Altenbach C; Greenhalgh D A; Khorana H G; Hubbell W L
A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1667-71.
1993: Farahbakhsh Z T; Hideg K; Hubbell W L
Photoactivated conformational changes in rhodopsin: a time-resolved spin label study.
Science (New York, N.Y.) 1993;262(5138):1416-9.
1993: Resek J F; Farahbakhsh Z T; Hubbell W L; Khorana H G
Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin.
Biochemistry 1993;32(45):12025-32.
1993: Perozo E; Hubbell W L
Voltage activation of reconstituted sodium channels: use of bacteriorhodopsin as a light-driven current source.
Biochemistry 1993;32(39):10471-8.
1993: Shin Y K; Levinthal C; Levinthal F; Hubbell W L
Colicin E1 binding to membranes: time-resolved studies of spin-labeled mutants.
Science (New York, N.Y.) 1993;259(5097):960-3.
1993: Wu G; Hubbell W L
Phospholipid asymmetry and transmembrane diffusion in photoreceptor disc membranes.
Biochemistry 1993;32(3):879-88.
1992: Farahbakhsh Z T; Altenbach C; Hubbell W L
Spin labeled cysteines as sensors for protein-lipid interaction and conformation in rhodopsin.
Photochemistry and photobiology 1992;56(6):1019-33.
1992: Shin Y K; Hubbell W L
Determination of electrostatic potentials at biological interfaces using electron-electron double resonance.
Biophysical journal 1992;61(6):1443-53.
1992: Anthony-Cahill S J; Benfield P A; Fairman R; Wasserman Z R; Brenner S L; Stafford W F; Altenbach C; Hubbell W L; DeGrado W F
Molecular characterization of helix-loop-helix peptides.
Science (New York, N.Y.) 1992;255(5047):979-83.
1991: Greenhalgh D A; Altenbach C; Hubbell W L; Khorana H G
Locations of Arg-82, Asp-85, and Asp-96 in helix C of bacteriorhodopsin relative to the aqueous boundaries.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8626-30.
1991: Levinthal F; Todd A P; Hubbell W L; Levinthal C
A single tryptic fragment of colicin E1 can form an ion channel: stoichiometry confirms kinetics.
Proteins 1991;11(4):254-62.
1990: Tosteson M T; Alvarez O; Hubbell W; Bieganski R M; Attenbach C; Caporales L H; Levy J J; Nutt R F; Rosenblatt M; Tosteson D C
Primary structure of peptides and ion channels. Role of amino acid side chains in voltage gating of melittin channels.
Biophysical journal 1990;58(6):1367-75.
1990: Oldenburg K R; Hubbell W L
Invertebrate rhodopsin cleavage by an endogenous calcium activated protease.
Experimental eye research 1990;51(4):463-72.
1990: Altenbach C; Marti T; Khorana H G; Hubbell W L
Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants.
Science (New York, N.Y.) 1990;248(4959):1088-92.
1990: Hubbell W L
Transbilayer coupling mechanism for the formation of lipid asymmetry in biological membranes. Application to the photoreceptor disc membrane.
Biophysical journal 1990;57(1):99-108.
1990: Tsui F C; Sundberg S A; Hubbell W L
Distribution of charge on photoreceptor disc membranes and implications for charged lipid asymmetry.
Biophysical journal 1990;57(1):85-97.
1989: Altenbach C; Froncisz W; Hyde J S; Hubbell W L
Conformation of spin-labeled melittin at membrane surfaces investigated by pulse saturation recovery and continuous wave power saturation electron paramagnetic resonance.
Biophysical journal 1989;56(6):1183-91.
1989: Altenbach C; Flitsch S L; Khorana H G; Hubbell W L
Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines.
Biochemistry 1989;28(19):7806-12.
1989: Todd A P; Cong J; Levinthal F; Levinthal C; Hubbell W L
Site-directed mutagenesis of colicin E1 provides specific attachment sites for spin labels whose spectra are sensitive to local conformation.
Proteins 1989;6(3):294-305.
1988: Altenbach C; Hubbell W L
The aggregation state of spin-labeled melittin in solution and bound to phospholipid membranes: evidence that membrane-bound melittin is monomeric.
Proteins 1988;3(4):230-42.

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