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Wolfgang Huber

Research Profile

Chemicals & Drugs

Anatomy

Livers
Colon

Objects

Coffee

Living Beings

Disorders

Concepts & Ideas

Physiology

Enzyme Induction

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Publications

TOP 3
Franziska Ferk; Wolfgang W Huber; Metka Filipic; Julia Bichler; Elisabeth Haslinger; Miroslav Misík; Armen K Nersesyan; Bettina Grasl-Kraupp; Bojana Zegura; Siegfried Knasmüller
Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ).
Wolfgang W Huber; Walter Rossmanith; Michael Grusch; Elisabeth Haslinger; Sonja Prustomersky; Barbara Peter-Vörösmarty; Wolfram Parzefall; Gerlinde Scharf; Rolf Schulte-Hermann
Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.
Wolfgang W Huber; Wolfram Parzefall
Thiols and the chemoprevention of cancer.

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All Publications

2010: Franziska Ferk; Wolfgang W Huber; Metka Filipic; Julia Bichler; Elisabeth Haslinger; Miroslav Misík; Armen K Nersesyan; Bettina Grasl-Kraupp; Bojana Zegura; Siegfried Knasmüller
Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ).
Mutation research 2010;691(1-2):17-22.
2008: Wolfgang W Huber; Walter Rossmanith; Michael Grusch; Elisabeth Haslinger; Sonja Prustomersky; Barbara Peter-Vörösmarty; Wolfram Parzefall; Gerlinde Scharf; Rolf Schulte-Hermann
Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(4):1230-8.
2007: Wolfgang W Huber; Wolfram Parzefall
Thiols and the chemoprevention of cancer.
Current opinion in pharmacology 2007;7(4):404-9.
2005: Wolfgang W Huber; Wolfram Parzefall
Modification of N-acetyltransferases and glutathione S-transferases by coffee components: possible relevance for cancer risk.
Methods in enzymology 2005;401():307-41.
2004: Siegfried Knasmüller; Volker Mersch-Sundermann; Sebastian Kevekordes; Firouz Darroudi; Wolfgang W Huber; Christine Hoelzl; Julia Bichler; Bernhard J Majer
Use of human-derived liver cell lines for the detection of environmental and dietary genotoxicants; current state of knowledge.
Toxicology 2004;198(1-3):315-28.
2004: Siegfried Knasmüller; Christophe Cavin; Asima Chakraborty; Firouz Darroudi; Bernhard J Majer; Wolfgang W Huber; Veronika A Ehrlich
Structurally related mycotoxins ochratoxin A, ochratoxin B, and citrinin differ in their genotoxic activities and in their mode of action in human-derived liver (HepG2) cells: implications for risk assessment.
Nutrition and cancer 2004;50(2):190-7.
2003: Markus Zsivkovits; Kassie Fekadu; Gerhard Sontag; Ursula Nabinger; Wolfgang W Huber; Michael Kundi; Asima Chakraborty; Helmuth Foissy; Siegfried Knasmüller
Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different lactobacillus strains.
Carcinogenesis 2003;24(12):1913-8.
2003: Wolfgang W Huber; Gerlinde Scharf; Georg Nagel; Sonja Prustomersky; Rolf Schulte-Hermann; Bernd Kaina
Coffee and its chemopreventive components Kahweol and Cafestol increase the activity of O6-methylguanine-DNA methyltransferase in rat liver--comparison with phase II xenobiotic metabolism.
Mutation research 2003;522(1-2):57-68.
2003: Gerlinde Scharf; Sonja Prustomersky; Siegfried Knasmuller; Rolf Schulte-Hermann; Wolfgang W Huber
Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.
Nutrition and cancer 2003;45(1):74-83.
2002: Christophe Cavin; D Holzhaeuser; Gerlinde Scharf; Anne Constable; Wolfgang W Huber; Benoît Schilter
Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(8):1155-63.
2002: Wolfgang W Huber; Sonja Prustomersky; Evert Delbanco; Maria Uhl; Gerlinde Scharf; Robert J Turesky; Ricarda Thier; Rolf Schulte-Hermann
Enhancement of the chemoprotective enzymes glucuronosyl transferase and glutathione transferase in specific organs of the rat by the coffee components kahweol and cafestol.
Archives of toxicology 2002;76(4):209-17.
2002: Wolfgang W Huber; Gerlinde Scharf; Walter Rossmanith; Sonja Prustomersky; Bettina Grasl-Kraupp; Barbara Peter; Robert J Turesky; Rolf Schulte-Hermann
The coffee components kahweol and cafestol induce gamma-glutamylcysteine synthetase, the rate limiting enzyme of chemoprotective glutathione synthesis, in several organs of the rat.
Archives of toxicology 2002;75(11-12):685-94.
2001: Gerlinde Scharf; Sonja Prustomersky; Wolfgang W Huber
Elevation of glutathione levels by coffee components and its potential mechanisms.
Advances in experimental medicine and biology 2001;500():535-9.
2001: Evert Delbanco; Hermann M Bolt; Wolfgang W Huber; S Beken; Frank Geller; S Philippou; F H Brands; Thomas Brüning; Ricarda Thier
Glutathione transferase activities in renal carcinomas and adjacent normal renal tissues: factors influencing renal carcinogenesis induced by xenobiotics.
Archives of toxicology 2001;74(11):688-94.
2000: Alexandra Löw-Baselli; Wolfgang W Huber; M Käfer; Krystina Bukowska; Rolf Schulte-Hermann; Bettina Grasl-Kraupp
Failure to demonstrate chemoprevention by the monoterpene perillyl alcohol during early rat hepatocarcinogenesis: a cautionary note.
Carcinogenesis 2000;21(10):1869-77.
2000: C E Schwab; Wolfgang W Huber; Wolfram Parzefall; G Hietsch; Fekadu Kassie; Rolf Schulte-Hermann; S Knasmuller
Search for compounds that inhibit the genotoxic and carcinogenic effects of heterocyclic aromatic amines.
Critical reviews in toxicology 2000;30(1):1-69.
1997: Wolfgang W Huber; Bettina Grasl-Kraupp; H Stekel; C Gschwentner; H Lang; Rolf Schulte-Hermann
Inhibition instead of enhancement of lipid peroxidation by pretreatment with the carcinogenic peroxisome proliferator nafenopin in rat liver exposed to a high single dose of corn oil.
Archives of toxicology 1997;71(9):575-81.