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Ulrich auf dem Keller

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TOP 3
Ulrich auf dem Keller; Ulrich Eckhard; Barbara Fingleton; Anna Prudova; Christopher M Overall
Systems-level analysis of proteolytic events in increased vascular permeability and complement activation in skin inflammation.
Tamara Jefferson; Viktor Magdolen; Wladislaw Maier; Verena V Metz; Anke Ohler; Christopher M Overall; Claus U Pietrzik; Rolf Postina; Stefan Rose-John; Erwin E Sterchi; Heiko Traupe; Caroline Bellac; Judith S Bond; Claudia Broder; Athena Chalaris; Jana Hedrich; Arumugam Jayakumar; Ulrich auf dem Keller; Christoph Becker-Pauly
The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.
Ulrich auf dem Keller; Christopher M Overall
CLIPPER: an add-on to the Trans-Proteomic Pipeline for the automated analysis of TAILS N-terminomics data.

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All Publications

2013: Ulrich auf dem Keller; Ulrich Eckhard; Barbara Fingleton; Anna Prudova; Christopher M Overall
Systems-level analysis of proteolytic events in increased vascular permeability and complement activation in skin inflammation.
Science signaling 2013;6(258):rs2.
2013: Tamara Jefferson; Viktor Magdolen; Wladislaw Maier; Verena V Metz; Anke Ohler; Christopher M Overall; Claus U Pietrzik; Rolf Postina; Stefan Rose-John; Erwin E Sterchi; Heiko Traupe; Caroline Bellac; Judith S Bond; Claudia Broder; Athena Chalaris; Jana Hedrich; Arumugam Jayakumar; Ulrich auf dem Keller; Christoph Becker-Pauly
The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.
Cellular and molecular life sciences : CMLS 2013;70(2):309-33.
2012: Ulrich auf dem Keller; Christopher M Overall
CLIPPER: an add-on to the Trans-Proteomic Pipeline for the automated analysis of TAILS N-terminomics data.
Biological chemistry 2012;393(12):1477-83.
2012: Franziska Lieder; Felix Reisen; Matthias Schäfer; Gisbert Schneider; Gabriel Sollberger; Ulrich auf dem Keller; Hans-Dietmar Beer; Michael Detmar; Tim Geppert; Sabine Werner
Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening.
The Journal of biological chemistry 2012;287(39):33001-13.
2011: Oded Kleifeld; Anna Prudova; Ulrich auf dem Keller; Alain Doucet; Magda Gioia; Jayachandran N Kizhakkedathu; Christopher M Overall
Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates.
Nature protocols 2011;6(10):1578-611.
2011: Therese Wohlschlager; Katrin Zurfluh; Sibylle C Vonesch; Markus Aebi; Ulrich auf dem Keller; Silvia Bleuler-Martinez; Alex Butschi; Peter Gehrig; Michael O Hengartner; Markus Künzler
Nematotoxicity of Marasmius oreades agglutinin (MOA) depends on glycolipid binding and cysteine protease activity.
The Journal of biological chemistry 2011;286(35):30337-43.
2011: Christoph Becker-Pauly; Claudia Broder; Reinhild Kappelhoff; Anke Ohler; Ulrich auf dem Keller; Olivier Barré; Oliver Schilling; Andre Schütte; Walter Stöcker; Christopher M Overall
Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates.
Molecular & cellular proteomics : MCP 2011;10(9):M111.009233.
2011: Yuanmei Lou; Paul C McDonald; Andrew Minchinton; Arusha Oloumi; Christina Ostlund; Christopher M Overall; Fabio Pacchiano; Calvin Roskelley; Andrea Scozzafava; Claudiu T Supuran; Brent W Sutherland; Nadia Touisni; Dawn Waterhouse; Jean-Yves Winum; Ardalan Ahmadi; Ulrich auf dem Keller; Marcel Bally; Fabrizio Carta; Stephen Chia; Blaise Clarke; David Huntsman; Alastair Kyle; Samuel Leung; Shoukat Dedhar
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.
Cancer research 2011;71(9):3364-76.
2011: Oliver Schilling; Ulrich auf dem Keller; Christopher M Overall
Protease specificity profiling by tandem mass spectrometry using proteome-derived peptide libraries.
Methods in molecular biology (Clifton, N.J.) 2011;753():257-72.
2011: Oliver Schilling; Pitter F Huesgen; Olivier Barré; Ulrich auf dem Keller; Christopher M Overall
Characterization of the prime and non-prime active site specificities of proteases by proteome-derived peptide libraries and tandem mass spectrometry.
Nature protocols 2011;6(1):111-20.
2010: Ulrich auf dem Keller; Oliver Schilling
Proteomic techniques and activity-based probes for the system-wide study of proteolysis.
Biochimie 2010;92(11):1705-14.
2010: Ulrich auf dem Keller; Caroline L Bellac; Ying Li; Yuanmei Lou; Philipp F Lange; Richard Ting; Curtis Harwig; Reinhild Kappelhoff; Shoukat Dedhar; Michael J Adam; Thomas J Ruth; François Bénard; David M Perrin; Christopher M Overall
Novel matrix metalloproteinase inhibitor [18F]marimastat-aryltrifluoroborate as a probe for in vivo positron emission tomography imaging in cancer.
Cancer research 2010;70(19):7562-9.
2010: Matthias Schäfer; Sabine Dütsch; Ulrich auf dem Keller; Sabine Werner
Nrf2: a central regulator of UV protection in the epidermis.
Cell cycle (Georgetown, Tex.) 2010;9(15):2917-8.
2010: Matthias Schäfer; Sabine Dütsch; Ulrich auf dem Keller; Fatemeh Navid; Agatha Schwarz; Delinda A Johnson; Jeffrey A Johnson; Sabine Werner
Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis.
Genes & development 2010;24(10):1045-58.
2010: Anna Prudova; Ulrich auf dem Keller; Georgina S Butler; Christopher M Overall
Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics.
Molecular & cellular proteomics : MCP 2010;9(5):894-911.
2010: Ulrich auf dem Keller; Anna Prudova; Magda Gioia; Georgina S Butler; Christopher M Overall
A statistics-based platform for quantitative N-terminome analysis and identification of protease cleavage products.
Molecular & cellular proteomics : MCP 2010;9(5):912-27.
2010: Oded Kleifeld; Alain Doucet; Ulrich auf dem Keller; Anna Prudova; Oliver Schilling; Rajesh K Kainthan; Amanda E Starr; Leonard J Foster; Jayachandran N Kizhakkedathu; Christopher M Overall
Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products.
Nature biotechnology 2010;28(3):281-8.
2010: Reinhild Kappelhoff; Ulrich auf dem Keller; Christopher M Overall
Analysis of the degradome with the CLIP-CHIP microarray.
Methods in molecular biology (Clifton, N.J.) 2010;622():175-93.
2008: Yuanmei Lou; Olena Preobrazhenska; Ulrich auf dem Keller; Margaret Sutcliffe; Lorena Barclay; Paul C McDonald; Calvin Roskelley; Christopher M Overall; Shoukat Dedhar
Epithelial-mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(10):2755-68.
2008: Richard Ting; Curtis Harwig; Ulrich auf dem Keller; Siobhan McCormick; Pamela Austin; Christopher M Overall; Michael J Adam; Thomas J Ruth; David M Perrin
Toward [18F]-labeled aryltrifluoroborate radiotracers: in vivo positron emission tomography imaging of stable aryltrifluoroborate clearance in mice.
Journal of the American Chemical Society 2008;130(36):12045-55.
2008: Tobias A Beyer; Weihua Xu; Daniel Teupser; Ulrich auf dem Keller; Philippe Bugnon; Eberhard Hildt; Joachim Thiery; Yuet Wai Kan; Sabine Werner
Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance.
The EMBO journal 2008;27(1):212-23.
2007: Tobias A Beyer; Ulrich auf dem Keller; Susanne Braun; M Schäfer; Sabine Werner
Roles and mechanisms of action of the Nrf2 transcription factor in skin morphogenesis, wound repair and skin cancer.
Cell death and differentiation 2007;14(7):1250-4.
2007: Moritz Durchdewald; Tobias A Beyer; Delinda A Johnson; Jeffrey A Johnson; Sabine Werner; Ulrich auf dem Keller
Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo.
The Journal of investigative dermatology 2007;127(3):646-53.
2006: Ulrich auf dem Keller; Angelika Kümin; Susanne Braun; Sabine Werner
Reactive oxygen species and their detoxification in healing skin wounds.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2006;11(1):106-11.
2006: Ulrich auf dem Keller; Marcel Huber; Tobias A Beyer; Angelika Kümin; Christina Siemes; Susanne Braun; Philippe Bugnon; Varvara Mitropoulos; Delinda A Johnson; Jeffrey A Johnson; Daniel Hohl; Sabine Werner
Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing.
Molecular and cellular biology 2006;26(10):3773-84.
2004: Susanne Braun; Ulrich auf dem Keller; Heike Steiling; Sabine Werner
Fibroblast growth factors in epithelial repair and cytoprotection.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1445):753-7.
2002: Susanne Braun; Christine Hanselmann; Marcus G Gassmann; Ulrich auf dem Keller; Christiane Born-Berclaz; Kaimin Chan; Yuet Wai Kan; Sabine Werner
Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound.
Molecular and cellular biology 2002;22(15):5492-505.
2002: Susanne Braun; Ulrich auf dem Keller; Hans-Dietmar Beer; Monika Krampert; Mischa Müller; Sabine Werner; Clive Dickson; Sabine Werner
Meeting report: growth factors in development, repair and disease.
European journal of cell biology 2002;81(7):375-82.