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Gregory Acland

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Dogs

Disorders

Concepts & Ideas

Anatomy

Procedures

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequence

Physiology

Mutation

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Publications

TOP 3
Beltran William A; Allore Heather G; Johnson Elizabeth; Towle Virginia; Tao Weng; Acland Gregory M; Aguirre Gustavo D; Zeiss Caroline J
CREB1/ATF1 activation in photoreceptor degeneration and protection.
Parker Heidi G; VonHoldt Bridgett M; Quignon Pascale; Margulies Elliott H; Shao Stephanie; Mosher Dana S; Spady Tyrone C; Elkahloun Abdel; Cargill Michele; Jones Paul G; Maslen Cheryl L; Acland Gregory M; Sutter Nathan B; Kuroki Keiichi; Bustamante Carlos D; Wayne Robert K; Ostrander Elaine A
An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs.
Zhu Lan; Zhang Zhiwu; Friedenberg Steven; Jung Seung-Woo; Phavaphutanon Janjira; Vernier-Singer Margaret; Corey Elizabeth; Mateescu Raluca; Dykes Nathan; Sandler Jody; Acland Gregory; Lust George; Todhunter Rory
The long (and winding) road to gene discovery for canine hip dysplasia.

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All Publications

2009: Beltran William A; Allore Heather G; Johnson Elizabeth; Towle Virginia; Tao Weng; Acland Gregory M; Aguirre Gustavo D; Zeiss Caroline J
CREB1/ATF1 activation in photoreceptor degeneration and protection.
Investigative ophthalmology & visual science 2009;50(11):5355-63.
2009: Parker Heidi G; VonHoldt Bridgett M; Quignon Pascale; Margulies Elliott H; Shao Stephanie; Mosher Dana S; Spady Tyrone C; Elkahloun Abdel; Cargill Michele; Jones Paul G; Maslen Cheryl L; Acland Gregory M; Sutter Nathan B; Kuroki Keiichi; Bustamante Carlos D; Wayne Robert K; Ostrander Elaine A
An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs.
Science (New York, N.Y.) 2009;325(5943):995-8.
2009: Zhu Lan; Zhang Zhiwu; Friedenberg Steven; Jung Seung-Woo; Phavaphutanon Janjira; Vernier-Singer Margaret; Corey Elizabeth; Mateescu Raluca; Dykes Nathan; Sandler Jody; Acland Gregory; Lust George; Todhunter Rory
The long (and winding) road to gene discovery for canine hip dysplasia.
Veterinary journal (London, England : 1997) 2009;181(2):97-110.
2009: Beltran William A; Acland Gregory M; Aguirre Gustavo D
Age-dependent disease expression determines remodeling of the retinal mosaic in carriers of RPGR exon ORF15 mutations.
Investigative ophthalmology & visual science 2009;50(8):3985-95.
2009: Kukekova Anna V; Vorobieva Nadegda V; Beklemisheva Violetta R; Johnson Jennifer L; Temnykh Svetlana V; Yudkin Dmitry V; Trut Lyudmila N; Andre Catherine; Galibert Francis; Aguirre Gustavo D; Acland Gregory M; Graphodatsky Alexander S
Chromosomal mapping of canine-derived BAC clones to the red fox and American mink genomes.
The Journal of heredity 2009;100 Suppl 1():S42-53.
2009: Gu Danian; Beltran William A; Pearce-Kelling Sue; Li Zexiao; Acland Gregory M; Aguirre Gustavo D
Steroids do not prevent photoreceptor degeneration in the light-exposed T4R rhodopsin mutant dog retina irrespective of AP-1 inhibition.
Investigative ophthalmology & visual science 2009;50(7):3482-94.
2009: Kukekova Anna V; Goldstein Orly; Johnson Jennifer L; Richardson Malcolm A; Pearce-Kelling Susan E; Swaroop Anand; Friedman James S; Aguirre Gustavo D; Acland Gregory M
Canine RD3 mutation establishes rod-cone dysplasia type 2 (rcd2) as ortholog of human and murine rd3.
Mammalian genome : official journal of the International Mammalian Genome Society 2009;20(2):109-23.
2009: Castelhano Marta G P; Acland Gregory M; Ciccone Penelope A; Corey Elizabeth E; Mezey Jason G; Schimenti John C; Todhunter Rory J
Development and use of DNA archives at veterinary teaching hospitals to investigate the genetic basis of disease in dogs.
Journal of the American Veterinary Medical Association 2009;234(1):75-80.
2008: Komáromy A M; Alexander J J; Cooper A E; Chiodo V A; Glushakova L G; Acland G M; Hauswirth W W; Aguirre G D
Targeting gene expression to cones with human cone opsin promoters in recombinant AAV.
Gene therapy 2008;15(14):1049-55.
2008: Komáromy András M; Acland Gregory M; Aguirre Gustavo D
Operating in the dark: a night-vision system for surgery in retinas susceptible to light damage.
Archives of ophthalmology 2008;126(5):714-7.
2008: Bennicelli Jeannette; Wright John Fraser; Komaromy Andras; Jacobs Jonathan B; Hauck Bernd; Zelenaia Olga; Mingozzi Federico; Hui Daniel; Chung Daniel; Rex Tonia S; Wei Zhangyong; Qu Guang; Zhou Shangzhen; Zeiss Caroline; Arruda Valder R; Acland Gregory M; Dell'Osso Lou F; High Katherine A; Maguire Albert M; Bennett Jean
Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(3):458-65.
2008: Kukekova Anna V; Trut L N; Chase K; Shepeleva D V; Vladimirova A V; Kharlamova A V; Oskina I N; Stepika A; Klebanov S; Erb H N; Acland G M
Measurement of segregating behaviors in experimental silver fox pedigrees.
Behavior genetics 2008;38(2):185-94.
2008: Greller Andrew L; Hoffman Allison R; Liu Chengcheng; Ying Gui-shuang; Vudathala Daljit K; Acland Gregory M; Komáromy András M
Effects of the topically applied calcium-channel blocker flunarizine on intraocular pressure in clinically normal dogs.
American journal of veterinary research 2008;69(2):273-8.
2008: Paez Gerardo L; Zangerl Barbara; Sellers Kimberly; Acland Gregory M; Aguirre Gustavo D
Characterization of gene expression profiles of normal canine retina and brain using a retinal cDNA microarray.
Advances in experimental medicine and biology 2008;613():179-84.
2007: Gu Danian; Beltran William A; Li Zexiao; Acland Gregory M; Aguirre Gustavo D
Clinical light exposure, photoreceptor degeneration, and AP-1 activation: a cell death or cell survival signal in the rhodopsin mutant retina?
Investigative ophthalmology & visual science 2007;48(11):4907-18.
2007: Parker Heidi G; Kukekova Anna V; Akey Dayna T; Goldstein Orly; Kirkness Ewen F; Baysac Kathleen C; Mosher Dana S; Aguirre Gustavo D; Acland Gregory M; Ostrander Elaine A
Breed relationships facilitate fine-mapping studies: a 7.8-kb deletion cosegregates with Collie eye anomaly across multiple dog breeds.
Genome research 2007;17(11):1562-71.
2007: Liu Tian; Todhunter Rory J; Wu Song; Hou Wei; Mateescu Raluca; Zhang Zhiwu; Burton-Wurster Nancy I; Acland Gregory M; Lust George; Wu Rongling
A random model for mapping imprinted quantitative trait loci in a structured pedigree: an implication for mapping canine hip dysplasia.
Genomics 2007;90(2):276-84.
2007: Aguirre Geoffrey K; Komáromy András M; Cideciyan Artur V; Brainard David H; Aleman Tomas S; Roman Alejandro J; Avants Brian B; Gee James C; Korczykowski Marc; Hauswirth William W; Acland Gregory M; Aguirre Gustavo D; Jacobson Samuel G
Canine and human visual cortex intact and responsive despite early retinal blindness from RPE65 mutation.
PLoS medicine 2007;4(6):e230.
2007: Guziewicz Karina E; Zangerl Barbara; Lindauer Sarah J; Mullins Robert F; Sandmeyer Lynne S; Grahn Bruce H; Stone Edwin M; Acland Gregory M; Aguirre Gustavo D
Bestrophin gene mutations cause canine multifocal retinopathy: a novel animal model for best disease.
Investigative ophthalmology & visual science 2007;48(5):1959-67.
2007: Beltran William A; Wen Rong; Acland Gregory M; Aguirre Gustavo D
Intravitreal injection of ciliary neurotrophic factor (CNTF) causes peripheral remodeling and does not prevent photoreceptor loss in canine RPGR mutant retina.
Experimental eye research 2007;84(4):753-71.
2007: Kukekova Anna V; Trut Lyudmila N; Oskina Irina N; Johnson Jennifer L; Temnykh Svetlana V; Kharlamova Anastasiya V; Shepeleva Darya V; Gulievich Rimma G; Shikhevich Svetlana G; Graphodatsky Alexander S; Aguirre Gustavo D; Acland Gregory M
A meiotic linkage map of the silver fox, aligned and compared to the canine genome.
Genome research 2007;17(3):387-99.
2007: Guyon Richard; Pearce-Kelling Susan E; Zeiss Caroline J; Acland Gregory M; Aguirre Gustavo D
Analysis of six candidate genes as potential modifiers of disease expression in canine XLPRA1, a model for human X-linked retinitis pigmentosa 3.
Molecular vision 2007;13():1094-105.
2007: Zangerl Barbara; Johnson Jennifer L; Acland Gregory M; Aguirre Gustavo D
Independent origin and restricted distribution of RPGR deletions causing XLPRA.
The Journal of heredity 2007;98(5):526-30.
2007: Hunter Linda S; Sidjanin Duska J; Hijar Manuel Villagrasa; Johnson Jennifer L; Kirkness Ewen; Acland Gregory M; Aguirre Gustavo D
Cloning and characterization of canine PAX6 and evaluation as a candidate gene in a canine model of aniridia.
Molecular vision 2007;13():431-42.
2007: Yudkin D V; Trifonov V A; Kukekova A V; Vorobieva N V; Rubtsova N V; Yang F; Acland G M; Ferguson-Smith M A; Graphodatsky A S
Mapping of KIT adjacent sequences on canid autosomes and B chromosomes.
Cytogenetic and genome research 2007;116(1-2):100-3.
2006: Zangerl Barbara; Goldstein Orly; Philp Alisdair R; Lindauer Sarah J P; Pearce-Kelling Susan E; Mullins Robert F; Graphodatsky Alexander S; Ripoll Daniel; Felix Jeanette S; Stone Edwin M; Acland Gregory M; Aguirre Gustavo D
Identical mutation in a novel retinal gene causes progressive rod-cone degeneration in dogs and retinitis pigmentosa in humans.
Genomics 2006;88(5):551-63.
2006: Goldstein Orly; Zangerl Barbara; Pearce-Kelling Sue; Sidjanin Duska J; Kijas James W; Felix Jeanette; Acland Gregory M; Aguirre Gustavo D
Linkage disequilibrium mapping in domestic dog breeds narrows the progressive rod-cone degeneration interval and identifies ancestral disease-transmitting chromosome.
Genomics 2006;88(5):541-50.
2006: Liu Tian; Todhunter Rory J; Lu Qing; Schoettinger Lindsay; Li Hongying; Littell Ramon C; Burton-Wurster Nancy; Acland Gregory M; Lust George; Wu Rongling
Modeling extent and distribution of zygotic disequilibrium: implications for a multigenerational canine pedigree.
Genetics 2006;174(1):439-53.
2006: Zangerl Barbara; Sun Qi; Pillardy Jarek; Johnson Jennifer L; Schweitzer Peter A; Hernandez Alvaro G; Liu Lei; Acland Gregory M; Aguirre Gustavo D
Development and characterization of a normalized canine retinal cDNA library for genomic and expression studies.
Investigative ophthalmology & visual science 2006;47(6):2632-8.
2006: Jacobson Samuel G; Acland Gregory M; Aguirre Gustavo D; Aleman Tomas S; Schwartz Sharon B; Cideciyan Artur V; Zeiss Caroline J; Komaromy Andras M; Kaushal Shalesh; Roman Alejandro J; Windsor Elizabeth A M; Sumaroka Alexander; Pearce-Kelling Susan E; Conlon Thomas J; Chiodo Vincent A; Boye Sanford L; Flotte Terence R; Maguire Albert M; Bennett Jean; Hauswirth William W
Safety of recombinant adeno-associated virus type 2-RPE65 vector delivered by ocular subretinal injection.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(6):1074-84.
2006: Beltran William A; Hammond Pamela; Acland Gregory M; Aguirre Gustavo D
A frameshift mutation in RPGR exon ORF15 causes photoreceptor degeneration and inner retina remodeling in a model of X-linked retinitis pigmentosa.
Investigative ophthalmology & visual science 2006;47(4):1669-81.
2006: Kukekova Anna V; Nelson Jacquelyn; Kuchtey Rachel W; Lowe Jennifer K; Johnson Jennifer L; Ostrander Elaine A; Aguirre Gustavo D; Acland Gregory M
Linkage mapping of canine rod cone dysplasia type 2 (rcd2) to CFA7, the canine orthologue of human 1q32.
Investigative ophthalmology & visual science 2006;47(3):1210-5.
2006: Komáromy András M; Varner Signe E; de Juan Eugene; Acland Gregory M; Aguirre Gustavo D
Application of a new subretinal injection device in the dog.
Cell transplantation 2006;15(6):511-9.
2006: Paez Gerardo L; Sellers Kimberly F; Band Mark; Acland Gregory M; Zangerl Barbara; Aguirre Gustavo D
Characterization of gene expression profiles of normal canine retina and brain using a retinal cDNA microarray.
Molecular vision 2006;12():1048-56.
2006: Hunter Linda S; Sidjanin Duska J; Johnson Jennifer L; Zangerl Barbara; Galibert Francis; Andre Catherine; Kirkness Ewen; Talamas Elijah; Acland Gregory M; Aguirre Gustavo D
Radiation hybrid mapping of cataract genes in the dog.
Molecular vision 2006;12():588-96.
2005: Acland Gregory M; Aguirre Gustavo D; Bennett Jean; Aleman Tomas S; Cideciyan Artur V; Bennicelli Jeannette; Dejneka Nadine S; Pearce-Kelling Susan E; Maguire Albert M; Palczewski Krzysztof; Hauswirth William W; Jacobson Samuel G
Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(6):1072-82.
2005: Todhunter Rory J; Mateescu Raluca; Lust George; Burton-Wurster Nancy I; Dykes Nathan L; Bliss Stuart P; Williams Alma J; Vernier-Singer Margaret; Corey Elizabeth; Harjes Carlos; Quaas Richard L; Zhang Zhiwu; Gilbert Robert O; Volkman Dietrich; Casella George; Wu Rongling; Acland Gregory M
Quantitative trait loci for hip dysplasia in a cross-breed canine pedigree.
Mammalian genome : official journal of the International Mammalian Genome Society 2005;16(9):720-30.
2005: Cideciyan Artur V; Jacobson Samuel G; Aleman Tomas S; Gu Danian; Pearce-Kelling Susan E; Sumaroka Alexander; Acland Gregory M; Aguirre Gustavo D
In vivo dynamics of retinal injury and repair in the rhodopsin mutant dog model of human retinitis pigmentosa.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(14):5233-8.
2005: Mateescu R G; Zhang Z; Tsai K; Phavaphutanon J; Burton-Wurster N I; Lust G; Quaas R; Murphy K; Acland G M; Todhunter R J
Analysis of allele fidelity, polymorphic information content, and density of microsatellites in a genome-wide screening for hip dysplasia in a crossbreed pedigree.
The Journal of heredity 2005;96(7):847-53.
2005: Graphodatsky Alexander S; Kukekova Anna V; Yudkin Dmitry V; Trifonov Vladimir A; Vorobieva Nadezhda V; Beklemisheva Violetta R; Perelman Polina L; Graphodatskaya Daria A; Trut Lyudmila N; Yang Fengtang; Ferguson-Smith Malcolm A; Acland Gregory M; Aguirre Gustavo D
The proto-oncogene C-KIT maps to canid B-chromosomes.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2005;13(2):113-22.
2004: Zhu Li; Jang Geeng-Fu; Jastrzebska Beata; Filipek Slawomir; Pearce-Kelling Susan E; Aguirre Gustavo D; Stenkamp Ronald E; Acland Gregory M; Palczewski Krzysztof
A naturally occurring mutation of the opsin gene (T4R) in dogs affects glycosylation and stability of the G protein-coupled receptor.
The Journal of biological chemistry 2004;279(51):53828-39.
2004: Casse C; Acland G M; Aguirre G D
Cloning and mapping of canine KIAA1753.
Animal genetics 2004;35(4):358-9.
2004: Kukekova A V; Trut L N; Oskina I N; Kharlamova A V; Shikhevich S G; Kirkness E F; Aguirre G D; Acland G M
A marker set for construction of a genetic map of the silver fox (Vulpes vulpes).
The Journal of heredity 2004;95(3):185-94.
2004: Kijas James W; Zangerl Barbara; Miller Brian; Nelson Jacque; Kirkness Ewen F; Aguirre Gustavo D; Acland Gregory M
Cloning of the canine ABCA4 gene and evaluation in canine cone-rod dystrophies and progressive retinal atrophies.
Molecular vision 2004;10():223-32.
2003: Todhunter Rory J; Grohn Yjo T; Bliss Stuart P; Wilfand Ashley; Williams Alma J; Vernier-Singer Margaret; Burton-Wurster Nancy I; Dykes Nathan L; Wu Rongling; Casella George; Acland Gregory M; Lust George
Evaluation of multiple radiographic predictors of cartilage lesions in the hip joints of eight-month-old dogs.
American journal of veterinary research 2003;64(12):1472-8.
2003: Zhang Qi; Beltran William A; Mao Zuohua; Li Kui; Johnson Jennifer L; Acland Gregory M; Aguirre Gustavo D
Comparative analysis and expression of CLUL1, a cone photoreceptor-specific gene.
Investigative ophthalmology & visual science 2003;44(10):4542-9.
2003: Lou Xiang-Yang; Todhunter Rory J; Lin Min; Lu Qing; Liu Tian; Wang Zuoheng; Bliss Stuart P; Casella George; Acland Gregory M; Lust George; Wu Rongling
The extent and distribution of linkage disequilibrium in a multi-hierarchic outbred canine pedigree.
Mammalian genome : official journal of the International Mammalian Genome Society 2003;14(8):555-64.
2003: Kukekova Anna V; Aguirre Gustavo D; Acland Gregory M
Cloning and characterization of canine SHARP1 and its evaluation as a positional candidate for canine early retinal degeneration (erd).
Gene 2003;312():335-43.
2003: Lowe Jennifer K; Kukekova Anna V; Kirkness Ewen F; Langlois Mariela C; Aguirre Gustavo D; Acland Gregory M; Ostrander Elaine A
Linkage mapping of the primary disease locus for collie eye anomaly.
Genomics 2003;82(1):86-95.
2003: Todhunter Rory J; Casella George; Bliss Stuart P; Lust George; Williams Alma Jo; Hamilton Samuel; Dykes Nathan L; Yeager Amy E; Gilbert Robert O; Burton-Wurster Nancy I; Mellersh Cathryn C; Acland Gregory M
Power of a Labrador Retriever-Greyhound pedigree for linkage analysis of hip dysplasia and osteoarthritis.
American journal of veterinary research 2003;64(4):418-24.
2003: Acland G M; Ostrander E A
The dog that came in from the cold.
Heredity 2003;90(3):201-2.
2003: Sidjanin D J; Miller B; Kijas J; McElwee J; Pillardy J; Malek J; Pai G; Feldblyum T; Fraser C; Acland G; Aguirre G
Radiation hybrid map, physical map, and low-pass genomic sequence of the canine prcd region on CFA9 and comparative mapping with the syntenic region on human chromosome 17.
Genomics 2003;81(2):138-48.
2003: Todhunter R J; Bliss S P; Casella G; Wu R; Lust G; Burton-Wurster N I; Williams A J; Gilbert R O; Acland G M
Genetic structure of susceptibility traits for hip dysplasia and microsatellite informativeness of an outcrossed canine pedigree.
The Journal of heredity 2003;94(1):39-48.
2003: Kijas J W; Miller B J; Pearce-Kelling S E; Aguirre G D; Acland G M
Canine models of ocular disease: outcross breedings define a dominant disorder present in the English mastiff and bull mastiff dog breeds.
The Journal of heredity 2003;94(1):27-30.
2002: Tao Weng; Wen Rong; Goddard Moses B; Sherman Sandy D; O'Rourke Pam J; Stabila Paul F; Bell William J; Dean Brenda J; Kauper Konrad A; Budz Veronica A; Tsiaras William G; Acland Gregory M; Pearce-Kelling Sue; Laties Alan M; Aguirre Gustavo D
Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa.
Investigative ophthalmology & visual science 2002;43(10):3292-8.
2002: Sidjanin Duska J; Lowe Jennifer K; McElwee John L; Milne Bruce S; Phippen Taryn M; Sargan David R; Aguirre Gustavo D; Acland Gregory M; Ostrander Elaine A
Canine CNGB3 mutations establish cone degeneration as orthologous to the human achromatopsia locus ACHM3.
Human molecular genetics 2002;11(16):1823-33.
2002: Bliss Stuart; Todhunter Rory J; Quaas Richard; Casella George; Wu Rongling; Lust George; Williams Alma Jo; Hamilton Samuel; Dykes Nathan L; Yeager Amy; Gilbert Robert O; Burton-Wurster Nancy I; Acland Gregory M
Quantitative genetics of traits associated with hip dysplasia in a canine pedigree constructed by mating dysplastic Labrador Retrievers with unaffected Greyhounds.
American journal of veterinary research 2002;63(7):1029-35.
2002: Zhang Qi; Acland Gregory M; Wu Wen X; Johnson Jennifer L; Pearce-Kelling Sue; Tulloch Brian; Vervoort Raf; Wright Alan F; Aguirre Gustavo D
Different RPGR exon ORF15 mutations in Canids provide insights into photoreceptor cell degeneration.
Human molecular genetics 2002;11(9):993-1003.
2002: Sidjanin D J; Zangerl B; Johnson J L; Xue F; Mellersh C; Ostrander E A; Acland G; Aguirre G D
Cloning of the canine delta tubulin cDNA (TUBD) and mapping to CFA9.
Animal genetics 2002;33(2):161-2.
2002: Kijas James W; Cideciyan Artur V; Aleman Tomas S; Pianta Michael J; Pearce-Kelling Susan E; Miller Brian J; Jacobson Samuel G; Aguirre Gustavo D; Acland Gregory M
Naturally occurring rhodopsin mutation in the dog causes retinal dysfunction and degeneration mimicking human dominant retinitis pigmentosa.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6328-33.
2002: Akhmedov Novrouz B; Baldwin Victoria J; Zangerl Barbara; Kijas James W; Hunter Linda; Minoofar Katayoun D; Mellersh Cathryn; Ostrander Elaine A; Acland Gregory M; Farber Debora B; Aguirre Gustavo D
Cloning and characterization of the canine photoreceptor specific cone-rod homeobox (CRX) gene and evaluation as a candidate for early onset photoreceptor diseases in the dog.
Molecular vision 2002;8():79-84.
2002: Zangerl B; Zhang Q; Acland G M; Aguirre G D
Characterization of three microsatellite loci linked to the canine RP3 interval.
The Journal of heredity 2002;93(1):70-3.
2002: Pellegrini Beth; Acland Gregory M; Ray Jharna
Cloning and characterization of opticin cDNA: evaluation as a candidate for canine oculo-skeletal dysplasia.
Gene 2002;282(1-2):121-31.
2001: Sidjanin D J; Xue F; McElwee J; Johnson J L; Holmgren C; Mellersh C; Ostrander E; Acland G; Aguirre G D
Cloning of canine gamma-tubulin (TUBG1) cDNA and mapping to CFA9.
Animal genetics 2001;32(5):328-9.
2001: Zhang Q; Acland G M; Zangerl B; Johnson J L; Mao Z; Zeiss C J; Ostrander E A; Aguirre G D
Fine mapping of canine XLPRA establishes homology of the human and canine RP3 intervals.
Investigative ophthalmology & visual science 2001;42(11):2466-71.
2001: Acland G M; Aguirre G D; Ray J; Zhang Q; Aleman T S; Cideciyan A V; Pearce-Kelling S E; Anand V; Zeng Y; Maguire A M; Jacobson S G; Hauswirth W W; Bennett J
Gene therapy restores vision in a canine model of childhood blindness.
Nature genetics 2001;28(1):92-5.
2001: Pearce-Kelling S E; Aleman T S; Nickle A; Laties A M; Aguirre G D; Jacobson S G; Acland G M
Calcium channel blocker D-cis-diltiazem does not slow retinal degeneration in the PDE6B mutant rcd1 canine model of retinitis pigmentosa.
Molecular vision 2001;7():42-7.
2000: Du F; Acland G M; Ray J
Cloning and expression of type II collagen mRNA: evaluation as a candidate for canine oculo-skeletal dysplasia.
Gene 2000;255(2):307-16.
2000: Zeiss C J; Ray K; Acland G M; Aguirre G D
Mapping of X-linked progressive retinal atrophy (XLPRA), the canine homolog of retinitis pigmentosa 3 (RP3).
Human molecular genetics 2000;9(4):531-7.
2000: Zhang Q; Ray K; Acland G M; Czarnecki J M; Aguirre G D
Molecular cloning, characterization and expression of a novel retinal clusterin-like protein cDNA.
Gene 2000;243(1-2):151-60.
2000: Bennett J; Anand V; Acland G M; Maguire A M
Cross-species comparison of in vivo reporter gene expression after recombinant adeno-associated virus-mediated retinal transduction.
Methods in enzymology 2000;316():777-89.
1999: Zeiss C J; Acland G M; Aguirre G D
Retinal pathology of canine X-linked progressive retinal atrophy, the locus homologue of RP3.
Investigative ophthalmology & visual science 1999;40(13):3292-304.
1999: Wang W; Acland G M; Ray K; Aguirre G D
Evaluation of cGMP-phosphodiesterase (PDE) subunits for causal association with rod-cone dysplasia 2 (rcd2), a canine model of abnormal retinal cGMP metabolism.
Experimental eye research 1999;69(4):445-53.
1999: Chen H; Ray J; Scarpino V; Acland G M; Aguirre G D; Anderson R E
Synthesis and release of docosahexaenoic acid by the RPE cells of prcd-affected dogs.
Investigative ophthalmology & visual science 1999;40(10):2418-22.
1999: Wang W; Zhang Q; Acland G M; Mellersh C; Ostrander E A; Ray K; Aguirre G D
Molecular characterization and mapping of canine cGMP-phosphodiesterase delta subunit (PDE6D).
Gene 1999;236(2):325-32.
1999: Werner P; Mellersh C S; Raducha M G; DeRose S; Acland G M; Prociuk U; Wiegand N; Aguirre G D; Henthorn P S; Patterson D F; Ostrander E A
Anchoring of canine linkage groups with chromosome-specific markers.
Mammalian genome : official journal of the International Mammalian Genome Society 1999;10(8):814-23.
1999: Acland G M; Ray K; Mellersh C S; Langston A A; Rine J; Ostrander E A; Aguirre G D
A novel retinal degeneration locus identified by linkage and comparative mapping of canine early retinal degeneration.
Genomics 1999;59(2):134-42.
1999: Dudus L; Anand V; Acland G M; Chen S J; Wilson J M; Fisher K J; Maguire A M; Bennett J
Persistent transgene product in retina, optic nerve and brain after intraocular injection of rAAV.
Vision research 1999;39(15):2545-53.
1999: Gu W; Ray K; Pearce-Kelling S; Baldwin V J; Langston A A; Ray J; Ostrander E A; Acland G M; Aguirre G D
Evaluation of the APOH gene as a positional candidate for prcd in dogs.
Investigative ophthalmology & visual science 1999;40(6):1229-37.
1999: Neff M W; Broman K W; Mellersh C S; Ray K; Acland G M; Aguirre G D; Ziegle J S; Ostrander E A; Rine J
A second-generation genetic linkage map of the domestic dog, Canis familiaris.
Genetics 1999;151(2):803-20.
1999: Aguirre G D; Baldwin V; Weeks K M; Acland G M; Ray K
Frequency of the codon 807 mutation in the cGMP phosphodiesterase beta-subunit gene in Irish setters and other dog breeds with hereditary retinal degeneration.
The Journal of heredity 1999;90(1):143-7.
1999: Ray K; Wang W; Czarnecki J; Zhang Q; Acland G M; Aguirre G D
Strategies for identification of mutations causing hereditary retinal diseases in dogs: evaluation of opsin as a candidate gene.
The Journal of heredity 1999;90(1):133-7.
1999: Todhunter R J; Acland G M; Olivier M; Williams A J; Vernier-Singer M; Burton-Wurster N; Farese J P; Gröhn Y T; Gilbert R O; Dykes N L; Lust G
An outcrossed canine pedigree for linkage analysis of hip dysplasia.
The Journal of heredity 1999;90(1):83-92.
1999: Zhang Q; Baldwin V J; Acland G M; Parshall C J; Haskel J; Aguirre G D; Ray K
Photoreceptor dysplasia (pd) in miniature schnauzer dogs: evaluation of candidate genes by molecular genetic analysis.
The Journal of heredity 1999;90(1):57-61.
1999: Langston A A; Mellersh C S; Wiegand N A; Acland G M; Ray K; Aguirre G D; Ostrander E A
Toward a framework linkage map of the canine genome.
The Journal of heredity 1999;90(1):7-14.
1999: Anderson R E; Maude M B; Alvarez R A; Acland G; Aguirre G D
A hypothesis to explain the reduced blood levels of docosahexaenoic acid in inherited retinal degenerations caused by mutations in genes encoding retina-specific proteins.
Lipids 1999;34 Suppl():S235-7.
1998: Zeiss C J; Acland G M; Aguirre G D; RayK
TIMP-1 expression is increased in X-linked progressive retinal atrophy despite its exclusion as a candidate gene.
Gene 1998;225(1-2):67-75.
1998: Delton-Vandenbroucke I; Maude M B; Chen H; Aguirre G D; Acland G M; Anderson R E
Effect of diet on the fatty acid and molecular species composition of dog retina phospholipids.
Lipids 1998;33(12):1187-93.
1998: Aguirre G D; Baldwin V; Pearce-Kelling S; Narfström K; Ray K; Acland G M
Congenital stationary night blindness in the dog: common mutation in the RPE65 gene indicates founder effect.
Molecular vision 1998;4():23.
1998: Du F; Acland G M; Ray J
A highly polymorphic PCR/RFLP marker in the canine type II collagen gene (COL2A1).
Animal genetics 1998;29(5):407-8.
1998: Akhmedov N B; Piriev N I; Pearce-Kelling S; Acland G M; Aguirre G D; Farber D B
Canine cone transducin-gamma gene and cone degeneration in the cd dog.
Investigative ophthalmology & visual science 1998;39(10):1775-81.
1998: Gu W; Acland G M; Langston A A; Ostrander E A; Aguirre G D; Ray K
Identification of a RAPD marker linked to progressive rod-cone degeneration in dogs.
Mammalian genome : official journal of the International Mammalian Genome Society 1998;9(9):740-4.
1998: Zhang Q; Acland G M; Parshall C J; Haskell J; Ray K; Aguirre G D
Characterization of canine photoreceptor phosducin cDNA and identification of a sequence variant in dogs with photoreceptor dysplasia.
Gene 1998;215(2):231-9.
1998: Acland G M; Ray K; Mellersh C S; Gu W; Langston A A; Rine J; Ostrander E A; Aguirre G D
Linkage analysis and comparative mapping of canine progressive rod-cone degeneration (prcd) establishes potential locus homology with retinitis pigmentosa (RP17) in humans.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3048-53.
1998: Du F; Acland G M; Ray J
Differential splicing of type II procollagen mRNA in canine retina.
Animal biotechnology 1998;9(1):15-20.
1997: Mellersh C S; Langston A A; Acland G M; Fleming M A; Ray K; Wiegand N A; Francisco L V; Gibbs M; Aguirre G D; Ostrander E A
A linkage map of the canine genome.
Genomics 1997;46(3):326-36.
1997: Langston A A; Mellersh C S; Neal C L; Ray K; Acland G M; Gibbs M; Aguirre G D; Fournier R E; Ostrander E A
Construction of a panel of canine-rodent hybrid cell lines for use in partitioning of the canine genome.
Genomics 1997;46(3):317-25.
1997: Aguirre G D; Acland G M; Maude M B; Anderson R E
Diets enriched in docosahexaenoic acid fail to correct progressive rod-cone degeneration (prcd) phenotype.
Investigative ophthalmology & visual science 1997;38(11):2387-407.
1997: Zhang Q; Pearce-kelling S; Acland G M; Aguirre G D; Ray K
Canine rod photoreceptor cGMP-gated channel protein alpha-subunit: studies on the expression of the gene and characterization of the cDNA.
Experimental eye research 1997;65(2):301-9.
1997: Akhmedov N B; Piriev N I; Ray K; Acland G M; Aguirre G D; Farber D B
Structure and analysis of the transducin beta3-subunit gene, a candidate for inherited cone degeneration (cd) in the dog.
Gene 1997;194(1):47-56.
1997: Ray K; Baldwin V J; Zeiss C; Acland G M; Aguirre G D
Canine rod transducin alpha-1: cloning of the cDNA and evaluation of the gene as a candidate for progressive retinal atrophy.
Current eye research 1997;16(1):71-7.
1996: Wang W; Acland G M; Aguirre G D; Ray K
Cloning and characterization of the cDNA and gene encoding the gamma-subunit of cGMP-phosphodiesterase in canine retinal rod photoreceptor cells.
Gene 1996;181(1-2):1-5.
1996: Ray K; Zeiss C; Acland G M; Trepanier L A; Aguirre G D
A highly polymorphic RFLP marker in the canine transducin alpha-1 subunit gene (GNAT1).
Animal genetics 1996;27(5):372-3.
1996: Gropp K E; Szél A; Huang J C; Acland G M; Farber D B; Aguirre G D
Selective absence of cone outer segment beta 3-transducin immunoreactivity in hereditary cone degeneration (cd).
Experimental eye research 1996;63(3):285-96.
1996: Ray K; Trepanier L A; Acland G M; Aguirre G D
PCR/RFLP marker in the canine opsin gene.
Animal genetics 1996;27(4):293-4.
1996: Wang W; Acland G M; Aguirre G D; Ray K
Cloning and characterization of the cDNA encoding the alpha-subunit of cGMP-phosphodiesterase in canine retinal rod photoreceptor cells.
Molecular vision 1996;2():3.
1996: Ray K; Acland G M; Aguirre G D
Nonallelism of erd and prcd and exclusion of the canine RDS/peripherin gene as a candidate for both retinal degeneration loci.
Investigative ophthalmology & visual science 1996;37(5):783-94.
1995: Meyers-Wallen V N; Bowman L; Acland G M; Palmer V L; Schlafer D; Fajt V
Sry-negative XX sex reversal in the German shorthaired pointer dog.
The Journal of heredity 1995;86(5):369-74.
1995: Meyers-Wallen V N; Palmer V L; Acland G M; Hershfield B
Sry-negative XX sex reversal in the American cocker spaniel dog.
Molecular reproduction and development 1995;41(3):300-5.
1995: Ray K; Baldwin V J; Acland G M; Aguirre G D
Molecular diagnostic tests for ascertainment of genotype at the rod cone dysplasia 1 (rcd1) locus in Irish setters.
Current eye research 1995;14(3):243-7.
1994: Ray K; Baldwin V J; Acland G M; Blanton S H; Aguirre G D
Cosegregation of codon 807 mutation of the canine rod cGMP phosphodiesterase beta gene and rcd1.
Investigative ophthalmology & visual science 1994;35(13):4291-9.
1994: Acland G M; Blanton S H; Hershfield B; Aguiree G D
XLPRA: a canine retinal degeneration inherited as an X-linked trait.
American journal of medical genetics 1994;52(1):27-33.
1994: Anderson R E; Maude M B; Acland G; Aguirre G D
Plasma lipid changes in PRCD-affected and normal miniature poodles given oral supplements of linseed oil. Indications for the involvement of n-3 fatty acids in inherited retinal degenerations.
Experimental eye research 1994;58(2):129-37.
1994: Alvarez R A; Aguirre G D; Acland G M; Anderson R E
Docosapentaenoic acid is converted to docosahexaenoic acid in the retinas of normal and prcd-affected miniature poodle dogs.
Investigative ophthalmology & visual science 1994;35(2):402-8.
1991: Anderson R E; Maude M B; Alvarez R A; Acland G M; Aguirre G D
Plasma lipid abnormalities in the miniature poodle with progressive rod-cone degeneration.
Experimental eye research 1991;52(3):349-55.
1990: Acland G M; Halloran-Blanton S; Boughman J A; Aguirre G D
Segregation distortion in inheritance of progressive rod cone degeneration (prcd) in miniature poodle dogs.
American journal of medical genetics 1990;35(3):354-9.
1990: Acland G M; Fletcher R T; Chader G J; Aguirre G D
Retinal cyclic GMP and AMP in rod-cone dysplasia: comparison of assays in fixed and unfixed retinal tissues.
Ophthalmic research 1990;22(2):117-22.
1989: Acland G M; Fletcher R T; Gentleman S; Chader G J; Aguirre G D
Non-allelism of three genes (rcd1, rcd2 and erd) for early-onset hereditary retinal degeneration.
Experimental eye research 1989;49(6):983-98.
1989: Wetzel M G; Fahlman C; Maude M B; Alvarez R A; O'Brien P J; Acland G M; Aguirre G D; Anderson R E
Fatty acid metabolism in normal miniature poodles and those affected with progressive rod-cone degeneration (prcd).
Progress in clinical and biological research 1989;314():427-39.
1988: Aguirre G D; Acland G M
Variation in retinal degeneration phenotype inherited at the prcd locus.
Experimental eye research 1988;46(5):663-87.

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