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Trevor Humby

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Dinko Relkovic; Lawrence S Wilkinson; Jim J Hagan; Trevor Humby; Anthony R Isles
Enhanced appetitive learning and reversal learning in a mouse model for Prader-Willi syndrome.
Simon Trent; Gaurav Bedse; Tommaso Cassano; Trevor Humby; Obah A Ojarikre; William Davies
Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice.
Trevor Humby; Lawrence S Wilkinson
Assaying dissociable elements of behavioural inhibition and impulsivity: translational utility of animal models.

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All Publications

2012: Dinko Relkovic; Lawrence S Wilkinson; Jim J Hagan; Trevor Humby; Anthony R Isles
Enhanced appetitive learning and reversal learning in a mouse model for Prader-Willi syndrome.
Behavioral neuroscience 2012;126(3):488-92.
2012: Simon Trent; Gaurav Bedse; Tommaso Cassano; Trevor Humby; Obah A Ojarikre; William Davies
Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012;37(5):1267-74.
2011: Trevor Humby; Lawrence S Wilkinson
Assaying dissociable elements of behavioural inhibition and impulsivity: translational utility of animal models.
Current opinion in pharmacology 2011;11(5):534-9.
2010: Dinko Relkovic; Christine M Doe; Trevor Humby; Karen A Johnstone; James L Resnick; Anthony J Holland; James Hagan; Lawrence S Wilkinson; Anthony R Isles
Behavioural and cognitive abnormalities in an imprinting centre deletion mouse model for Prader-Willi syndrome.
The European journal of neuroscience 2010;31(1):156-64.
2009: William Davies; Trevor Humby; Wendy Kong; Tamara Otter; Paul S Burgoyne; Lawrence S Wilkinson
Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attention.
Biological psychiatry 2009;66(4):360-7.
2009: Christine M Doe; Dinko Relkovic; Alastair S Garfield; Jeffrey W Dalley; David E H Theobald; Trevor Humby; Lawrence S Wilkinson; Anthony R Isles
Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour.
Human molecular genetics 2009;18(12):2140-8.
2008: Sarah Donald; Trevor Humby; Ian Fyfe; Anne Segonds-Pichon; Simon A Walker; Simon R Andrews; W John Coadwell; Piers Emson; Lawrence S Wilkinson; Heidi C E Welch
P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4483-8.
2008: William Davies; Anthony R Isles; Trevor Humby; Lawrence S Wilkinson
What are imprinted genes doing in the brain?
Advances in experimental medicine and biology 2008;626():62-70.
2007: William Davies; Anthony R Isles; Trevor Humby; Lawrence S Wilkinson
What are imprinted genes doing in the brain?
Epigenetics : official journal of the DNA Methylation Society 2007;2(4):201-6.
2007: Sarah L Lambourne; Trevor Humby; Anthony R Isles; Piers C Emson; Maria Grazia Spillantini; Lawrence S Wilkinson
Impairments in impulse control in mice transgenic for the human FTDP-17 tauV337M mutation are exacerbated by age.
Human molecular genetics 2007;16(14):1708-19.
2007: William Davies; Trevor Humby; Anthony R Isles; Paul S Burgoyne; Lawrence S Wilkinson
X-monosomy effects on visuospatial attention in mice: a candidate gene and implications for Turner syndrome and attention deficit hyperactivity disorder.
Biological psychiatry 2007;61(12):1351-60.
2006: Rebecca E Colebrooke; Trevor Humby; Patrick J Lynch; Daniel McGowan; Jing Xia; Piers C Emson
Age-related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease.
The European journal of neuroscience 2006;24(9):2622-30.
2006: Anthony R Isles; Trevor Humby
Modes of imprinted gene action in learning disability.
Journal of intellectual disability research : JIDR 2006;50(Pt 5):318-25.
2006: George K Tofaris; Pablo Garcia Reitböck; Trevor Humby; Sarah L Lambourne; Mark O'Connell; Bernardino Ghetti; Helen Gossage; Piers C Emson; Lawrence S Wilkinson; Michel Goedert; Maria Grazia Spillantini
Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(15):3942-50.
2005: Anthony R Isles; Gareth J Hathway; Trevor Humby; Carlos de la Riva; Keith M Kendrick; Lawrence S Wilkinson
An mTph2 SNP gives rise to alterations in extracellular 5-HT levels, but not in performance on a delayed-reinforcement task.
The European journal of neuroscience 2005;22(4):997-1000.
2005: William Davies; Anthony R Isles; Rachel Smith; Delicia Karunadasa; Doreen Burrmann; Trevor Humby; Obah Ojarikre; Carol Biggin; David Skuse; Paul S Burgoyne; Lawrence Wilkinson
Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice.
Nature genetics 2005;37(6):625-9.
2005: Trevor Humby; Lawrence Wilkinson; Gerry Dawson
Assaying aspects of attention and impulse control in mice using the 5-choice serial reaction time task.
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] 2005;Chapter 8():Unit 8.5H.
2005: Antonius Plagge; Anthony R Isles; Emma Gordon; Trevor Humby; Wendy Dean; Sabine Gritsch; Reiner Fischer-Colbrie; Lawrence S Wilkinson; Gavin Kelsey
Imprinted Nesp55 influences behavioral reactivity to novel environments.
Molecular and cellular biology 2005;25(8):3019-26.
2004: Anthony R Isles; Trevor Humby; Eurof Walters; Lawrence S Wilkinson
Common genetic effects on variation in impulsivity and activity in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(30):6733-40.
2003: Anthony R Isles; Trevor Humby; Lawrence S Wilkinson
Measuring impulsivity in mice using a novel operant delayed reinforcement task: effects of behavioural manipulations and d-amphetamine.
Psychopharmacology 2003;170(4):376-82.
2001: S B Caine; Trevor Humby; Trevor W Robbins; Barry J Everitt
Behavioral effects of psychomotor stimulants in rats with dorsal or ventral subiculum lesions: locomotion, cocaine self-administration, and prepulse inhibition of startle.
Behavioral neuroscience 2001;115(4):880-94.
2001: Katrin A Mooslehner; Pok Man Chan; Weiming XU; L Liu; C Smadja; Trevor Humby; Nicholas D Allen; Lawrence S Wilkinson; Piers C Emson
Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism.
Molecular and cellular biology 2001;21(16):5321-31.
2001: christelle baunez; Trevor Humby; Dawn Eagle; L J Ryan; Stephen B Dunnett; Trevor W Robbins
Effects of STN lesions on simple vs choice reaction time tasks in the rat: preserved motor readiness, but impaired response selection.
The European journal of neuroscience 2001;13(8):1609-16.
1999: Dawn Eagle; Trevor Humby; Stephen B Dunnett; Trevor W Robbins
Effects of regional striatal lesions on motor, motivational, and executive aspects of progressive-ratio performance in rats.
Behavioral neuroscience 1999;113(4):718-31.
1999: Trevor Humby; F M Laird; William Davies; Lawrence S Wilkinson
Visuospatial attentional functioning in mice: interactions between cholinergic manipulations and genotype.
The European journal of neuroscience 1999;11(8):2813-23.
1999: Rebecca J Carter; LA Lione; Trevor Humby; L Mangiarini; Amarbirpal Mahal; Gillian P Bates; Stephen B Dunnett; A Jennifer Morton
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(8):3248-57.
1999: FS Hall; Lawrence S Wilkinson; Trevor Humby; Trevor W Robbins
Maternal deprivation of neonatal rats produces enduring changes in dopamine function.
Synapse (New York, N.Y.) 1999;32(1):37-43.
1998: FS Hall; Lawrence S Wilkinson; Trevor Humby; WL Inglis; D A Kendall; CD Marsden; Trevor W Robbins
Isolation rearing in rats: pre- and postsynaptic changes in striatal dopaminergic systems.
Pharmacology, biochemistry, and behavior 1998;59(4):859-72.
1998: Lawrence S Wilkinson; Trevor Humby; A S Killcross; E M Torres; Barry J Everitt; Trevor W Robbins
Dissociations in dopamine release in medial prefrontal cortex and ventral striatum during the acquisition and extinction of classical aversive conditioning in the rat.
The European journal of neuroscience 1998;10(3):1019-26.
1997: PJ Brasted; Trevor Humby; Stephen B Dunnett; Trevor W Robbins
Unilateral lesions of the dorsal striatum in rats disrupt responding in egocentric space.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(22):8919-26.
1997: FS Hall; Trevor Humby; Lawrence S Wilkinson; Trevor W Robbins
The effects of isolation-rearing on preference by rats for a novel environment.
Physiology & behavior 1997;62(2):299-303.
1997: FS Hall; Trevor Humby; Lawrence S Wilkinson; Trevor W Robbins
The effects of isolation-rearing on sucrose consumption in rats.
Physiology & behavior 1997;62(2):291-7.
1997: FS Hall; Trevor Humby; Lawrence S Wilkinson; Trevor W Robbins
The effects of isolation-rearing of rats on behavioural responses to food and environmental novelty.
Physiology & behavior 1997;62(2):281-90.
1996: Lawrence S Wilkinson; Trevor Humby; S Killcross; Trevor W Robbins; Barry J Everitt
Dissociations in hippocampal 5-hydroxytryptamine release in the rat following Pavlovian aversive conditioning to discrete and contextual stimuli.
The European journal of neuroscience 1996;8(7):1479-87.
1996: Trevor Humby; Lawrence S Wilkinson; Trevor W Robbins; Mark A Geyer
Prepulses inhibit startle-induced reductions of extracellular dopamine in the nucleus accumbens of rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(6):2149-56.
1995: Lawrence S Wilkinson; Trevor Humby; Trevor W Robbins; Barry J Everitt
Differential effects of forebrain 5-hydroxytryptamine depletions on Pavlovian aversive conditioning to discrete and contextual stimuli in the rat.
The European journal of neuroscience 1995;7(10):2042-52.
1994: Lawrence S Wilkinson; S S Killcross; Trevor Humby; FS Hall; Mark A Geyer; Trevor W Robbins
Social isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response without disrupting latent inhibition.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1994;10(1):61-72.
1993: Mark A Geyer; Lawrence S Wilkinson; Trevor Humby; Trevor W Robbins
Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia.
Biological psychiatry 1993;34(6):361-72.
1993: Lawrence S Wilkinson; G Mittleman; E Torres; Trevor Humby; FS Hall; Trevor W Robbins
Enhancement of amphetamine-induced locomotor activity and dopamine release in nucleus accumbens following excitotoxic lesions of the hippocampus.
Behavioural brain research 1993;55(2):143-50.
1992: S Mead; Francis J P Ebling; Elizabeth S Maywood; Trevor Humby; Joe Herbert; Michael H Hastings
A nonphotic stimulus causes instantaneous phase advances of the light-entrainable circadian oscillator of the Syrian hamster but does not induce the expression of c-fos in the suprachiasmatic nuclei.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(7):2516-22.
1992: Francis J P Ebling; Elizabeth S Maywood; Trevor Humby; Michael H Hastings
Circadian and photoperiodic time measurement in male Syrian hamsters following lesions of the melatonin-binding sites of the paraventricular thalamus.
Journal of biological rhythms 1992;7(3):241-54.
1991: Francis J P Ebling; Elizabeth S Maywood; K Staley; Trevor Humby; David C Hancock; C M Waters; G I Evant; Michael H Hastings
The role of N-methyl-d-aspartate-type glutamatergic neurotransmission in the photic induction of immediate-early gene expression in the suprachiasmatic nuclei of the Syrian hamster.
Journal of neuroendocrinology 1991;3(6):641-52.