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Sandy Humphreys
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Anatomy
Chemicals & Drugs
Activities & Behaviors
Physiology
Disorders
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Network (preview)
66
Frayn, Keith
16
Fielding, Barbara
15
Karpe, Fredrik
14
Clark, ML
13
Samra, JS
8
Gibbons, Geoffrey
7
Summers, Lucinda
5
Maclaren, D P M
5
Reilly, Thomas
5
Campbell, Iain
5
Tan, Garry
4
Vidal, Hubert
3
Matthews, David
3
Ainslie, Philip
3
Hardman, Adrianne
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Publications
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All Publications
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2009: Roberts R; Hodson L; Dennis A L; Neville M J; Humphreys S M; Harnden K E; Micklem K J; Frayn K N
Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans.
Diabetologia 2009;52(5):882-90.
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2009: Ruge Toralph; Hodson Leanne; Cheeseman Jane; Dennis A Louise; Fielding Barbara A; Humphreys Sandy M; Frayn Keith N; Karpe Fredrik
Fasted to fed trafficking of Fatty acids in human adipose tissue reveals a novel regulatory step for enhanced fat storage.
The Journal of clinical endocrinology and metabolism 2009;94(5):1781-8.
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2009: Funada Junichi; Betts Tim R; Hodson Leanne; Humphreys Sandy M; Timperley Jon; Frayn Keith N; Karpe Fredrik
Substrate utilization by the failing human heart by direct quantification using arterio-venous blood sampling.
PloS one 2009;4(10):e7533.
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2008: Bickerton A S T; Roberts R; Fielding B A; Tornqvist H; Blaak E E; Wagenmakers A J M; Gilbert M; Humphreys S M; Karpe F; Frayn K N
Adipose tissue fatty acid metabolism in insulin-resistant men.
Diabetologia 2008;51(8):1466-74.
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2008: Risérus Ulf; Sprecher Dennis; Johnson Tony; Olson Eric; Hirschberg Sandra; Liu Aixue; Fang Zeke; Hegde Priti; Richards Duncan; Sarov-Blat Leli; Strum Jay C; Basu Samar; Cheeseman Jane; Fielding Barbara A; Humphreys Sandy M; Danoff Theodore; Moore Niall R; Murgatroyd Peter; O'Rahilly Stephen; Sutton Pauline; Willson Tim; Hassall David; Frayn Keith N; Karpe Fredrik
Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men.
Diabetes 2008;57(2):332-9.
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2006: Tan G D; Neville M J; Liverani E; Humphreys S M; Currie J M; Dennis L; Fielding B A; Karpe F
The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank.
Diabetologia 2006;49(1):158-68.
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2005: Tan G D; Debard C; Funahashi T; Humphreys S M; Matsuzawa Y; Frayn K N; Karpe F; Vidal H
Changes in adiponectin receptor expression in muscle and adipose tissue of type 2 diabetic patients during rosiglitazone therapy.
Diabetologia 2005;48(8):1585-9.
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2005: Tan G D; Fielding B A; Currie J M; Humphreys S M; Désage M; Frayn K N; Laville M; Vidal H; Karpe F
The effects of rosiglitazone on fatty acid and triglyceride metabolism in type 2 diabetes.
Diabetologia 2005;48(1):83-95.
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2004: Tan Garry D; Goossens Gijs H; Humphreys Sandy M; Vidal Hubert; Karpe Fredrik
Upper and lower body adipose tissue function: a direct comparison of fat mobilization in humans.
Obesity research 2004;12(1):114-8.
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2003: Koutsari C; Karpe F; Humphreys S M; Frayn K N; Hardman A E
Plasma leptin is influenced by diet composition and exercise.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2003;27(8):901-6.
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2003: Tan Garry D; Debard Cyrille; Tiraby Claire; Humphreys Sandy M; Frayn Keith N; Langin Dominique; Vidal Hubert; Karpe Fredrik
A "futile cycle" induced by thiazolidinediones in human adipose tissue?
Nature medicine 2003;9(7):811-2; author reply 812.
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2003: Ainslie Philip N; Campbell Iain T; Frayn Keith N; Humphreys Sandy M; MacLaren Donald P M; Reilly Thomas
Physiological, metabolic, and performance implications of a prolonged hill walk: influence of energy intake.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;94(3):1075-83.
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2002: Ulahannan T J; Karpe F; Humphreys S M; Matthews D R; Frayn K N
Effects of acute administration of doxazosin on fasting and postprandial haemodynamics and lipid metabolism in healthy subjects.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2002;34(9):499-503.
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2002: Ainslie P N; Campbell I T; Frayn K N; Humphreys S M; MacLaren D P M; Reilly T; Westerterp K R
Energy balance, metabolism, hydration, and performance during strenuous hill walking: the effect of age.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;93(2):714-23.
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2002: Karpe F; Fielding B A; Ilic V; Humphreys S M; Frayn K N
Monitoring adipose tissue blood flow in man: a comparison between the (133)xenon washout method and microdialysis.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2002;26(1):1-5.
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2002: Ainslie P N; Campbell I T; Frayn K N; Humphreys S M; Maclaren D P M; Reilly T
Physiological and metabolic responses to a hill walk.
Journal of applied physiology (Bethesda, Md. : 1985) 2002;92(1):179-87.
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2001: Koutsari C; Karpe F; Humphreys S M; Frayn K N; Hardman A E
Exercise prevents the accumulation of triglyceride-rich lipoproteins and their remnants seen when changing to a high-carbohydrate diet.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(9):1520-5.
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2000: Malkova D; Evans R D; Frayn K N; Humphreys S M; Jones P R; Hardman A E
Prior exercise and postprandial substrate extraction across the human leg.
American journal of physiology. Endocrinology and metabolism 2000;279(5):E1020-8.
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2000: Fielding B A; Reid G; Grady M; Humphreys S M; Evans K; Frayn K N
Ethanol with a mixed meal increases postprandial triacylglycerol but decreases postprandial non-esterified fatty acid concentrations.
The British journal of nutrition 2000;83(6):597-604.
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2000: Summers L K; Barnes S C; Fielding B A; Beysen C; Ilic V; Humphreys S M; Frayn K N
Uptake of individual fatty acids into adipose tissue in relation to their presence in the diet.
The American journal of clinical nutrition 2000;71(6):1470-7.
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1999: Samra J S; Clark M L; Humphreys S M; MacDonald I A; Bannister P A; Matthews D R; Frayn K N
Suppression of the nocturnal rise in growth hormone reduces subsequent lipolysis in subcutaneous adipose tissue.
European journal of clinical investigation 1999;29(12):1045-52.
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1999: Summers L K; Clark M L; Humphreys S M; Bugler J; Frayn K N
The use of microdialysis to monitor rapid changes in glucose concentration.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1999;31(7):424-8.
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1998: Karpe F; Olivecrona T; Olivecrona G; Samra J S; Summers L K; Humphreys S M; Frayn K N
Lipoprotein lipase transport in plasma: role of muscle and adipose tissues in regulation of plasma lipoprotein lipase concentrations.
Journal of lipid research 1998;39(12):2387-93.
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1998: Abraha A; Humphreys S M; Clark M L; Matthews D R; Frayn K N
Acute effect of fructose on postprandial lipaemia in diabetic and non-diabetic subjects.
The British journal of nutrition 1998;80(2):169-75.
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1998: Samra J S; Giles S L; Summers L K; Evans R D; Arner P; Humphreys S M; Clark M L; Frayn K N
Peripheral fat metabolism during infusion of an exogenous triacylglycerol emulsion.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1998;22(8):806-12.
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1998: Whitley H A; Humphreys S M; Campbell I T; Keegan M A; Jayanetti T D; Sperry D A; MacLaren D P; Reilly T; Frayn K N
Metabolic and performance responses during endurance exercise after high-fat and high-carbohydrate meals.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;85(2):418-24.
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1998: Summers L K; Arner P; Ilic V; Clark M L; Humphreys S M; Frayn K N
Adipose tissue metabolism in the postprandial period: microdialysis and arteriovenous techniques compared.
The American journal of physiology 1998;274(4 Pt 1):E651-5.
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1998: Samra J S; Clark M L; Humphreys S M; MacDonald I A; Bannister P A; Frayn K N
Effects of physiological hypercortisolemia on the regulation of lipolysis in subcutaneous adipose tissue.
The Journal of clinical endocrinology and metabolism 1998;83(2):626-31.
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1997: Karpe F; Humphreys S M; Samra J S; Summers L K; Frayn K N
Clearance of lipoprotein remnant particles in adipose tissue and muscle in humans.
Journal of lipid research 1997;38(11):2335-43.
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1997: Whitley H A; Humphreys S M; Samra J S; Campbell I T; Maclaren D P; Reilly T; Frayn K N
Metabolic responses to isoenergetic meals containing different proportions of carbohydrate and fat.
The British journal of nutrition 1997;78(1):15-26.
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1996: Samra J S; Clark M L; Humphreys S M; Macdonald I A; Matthews D R; Frayn K N
Effects of morning rise in cortisol concentration on regulation of lipolysis in subcutaneous adipose tissue.
The American journal of physiology 1996;271(6 Pt 1):E996-1002.
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1996: Summers L K; Samra J S; Humphreys S M; Morris R J; Frayn K N
Subcutaneous abdominal adipose tissue blood flow: variation within and between subjects and relationship to obesity.
Clinical science (London, England : 1979) 1996;91(6):679-83.
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1996: Samra J S; Simpson E J; Clark M L; Forster C D; Humphreys S M; Macdonald I A; Frayn K N
Effects of epinephrine infusion on adipose tissue: interactions between blood flow and lipid metabolism.
The American journal of physiology 1996;271(5 Pt 1):E834-9.
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1996: Samra J S; Simpson E J; Clark M L; Forster C D; Humphreys S M; Macdonald I A; Frayn K N
Effects of adrenaline infusion on the interstitial environment of subcutaneous adipose tissue as studied by microdialysis.
Clinical science (London, England : 1979) 1996;91(4):425-30.
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1996: Halliwell K J; Fielding B A; Samra J S; Humphreys S M; Frayn K N
Release of individual fatty acids from human adipose tissue in vivo after an overnight fast.
Journal of lipid research 1996;37(9):1842-8.
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1996: Frayn K N; Humphreys S M; Coppack S W
Net carbon flux across subcutaneous adipose tissue after a standard meal in normal-weight and insulin-resistant obese subjects.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1996;20(9):795-800.
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1996: Samra J S; Clark M L; Humphreys S M; Macdonald I A; Frayn K N
Regulation of lipid metabolism in adipose tissue during early starvation.
The American journal of physiology 1996;271(3 Pt 1):E541-6.
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1996: Samra J S; Clark M L; Humphreys S M; Matthews D R; Frayn K N
Is the growth hormone concentration regulated by the morning rise in the plasma cortisol concentration?
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1996;28(5):237-40.
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1996: Frayn K N; Fielding B A; Humphreys S M; Coppack S W
Nutritional influences on human adipose-tissue metabolism.
Biochemical Society transactions 1996;24(2):422-6.
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1996: Coppack S W; Fisher R M; Humphreys S M; Clark M L; Pointon J J; Frayn K N
Carbohydrate metabolism in insulin resistance: glucose uptake and lactate production by adipose and forearm tissues in vivo before and after a mixed meal.
Clinical science (London, England : 1979) 1996;90(5):409-15.
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1995: Fielding B A; Humphreys S M; Shadid S; Frayn K N
Plasma mono-, di- and triacylglycerol measurements in a study of fat uptake by human adipose tissue in vivo.
Biochemical Society transactions 1995;23(3):487S.
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1995: Potts J L; Coppack S W; Fisher R M; Humphreys S M; Gibbons G F; Frayn K N
Impaired postprandial clearance of triacylglycerol-rich lipoproteins in adipose tissue in obese subjects.
The American journal of physiology 1995;268(4 Pt 1):E588-94.
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1995: Fisher R M; Coppack S W; Humphreys S M; Gibbons G F; Frayn K N
Human triacylglycerol-rich lipoprotein subfractions as substrates for lipoprotein lipase.
Clinica chimica acta; international journal of clinical chemistry 1995;236(1):7-17.
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1995: Carr R E; Humphreys S M; Frayn K N
Catecholamine interference with enzymatic determination of nonesterified fatty acids in two commercially available test kits.
Clinical chemistry 1995;41(3):455-7.
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1995: Frayn K N; Humphreys S M; Coppack S W
Fuel selection in white adipose tissue.
The Proceedings of the Nutrition Society 1995;54(1):177-89.
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1995: Frayn K N; Coppack S W; Fielding B A; Humphreys S M
Coordinated regulation of hormone-sensitive lipase and lipoprotein lipase in human adipose tissue in vivo: implications for the control of fat storage and fat mobilization.
Advances in enzyme regulation 1995;35():163-78.
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1994: Potts J L; Fisher R M; Humphreys S M; Gibbons G F; Frayn K N
Separation of lipoprotein fractions by ultracentrifugation: investigation of analytical recovery with sequential flotation and density gradient procedures.
Clinica chimica acta; international journal of clinical chemistry 1994;230(2):215-20.
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1994: Potts J L; Humphreys S M; Coppack S W; Fisher R M; Gibbons G F; Frayn K N
Fasting plasma triacylglycerol concentrations predict adverse changes in lipoprotein metabolism after a normal meal.
The British journal of nutrition 1994;72(1):101-9.
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1994: Frayn K N; Shadid S; Hamlani R; Humphreys S M; Clark M L; Fielding B A; Boland O; Coppack S W
Regulation of fatty acid movement in human adipose tissue in the postabsorptive-to-postprandial transition.
The American journal of physiology 1994;266(3 Pt 1):E308-17.
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1994: Griffiths A J; Humphreys S M; Clark M L; Frayn K N
Forearm substrate utilization during exercise after a meal containing both fat and carbohydrate.
Clinical science (London, England : 1979) 1994;86(2):169-75.
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1994: Griffiths A J; Humphreys S M; Clark M L; Fielding B A; Frayn K N
Immediate metabolic availability of dietary fat in combination with carbohydrate.
The American journal of clinical nutrition 1994;59(1):53-9.
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1993: Frayn K N; Coppack S W; Humphreys S M
Subcutaneous adipose tissue metabolism studied by local catheterization.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1993;17 Suppl 3():S18-21; discussion S22.
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1993: Fielding B A; Humphreys S M; Frayn K N
Mono- and di-acylglycerol concentrations in human plasma in relation to lipoprotein lipase activity.
Biochemical Society transactions 1993;21 ( Pt 3)(3):235S.
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1993: Fielding B A; Humphreys S M; Allman R F; Frayn K N
Mono-, di- and triacylglycerol concentrations in human plasma: effects of heparin injection and of a high-fat meal.
Clinica chimica acta; international journal of clinical chemistry 1993;216(1-2):167-73.
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1993: Frayn K N; Coppack S W; Humphreys S M; Clark M L; Evans R D
Periprandial regulation of lipid metabolism in insulin-treated diabetes mellitus.
Metabolism: clinical and experimental 1993;42(4):504-10.
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1992: Coppack S W; Evans R D; Fisher R M; Frayn K N; Gibbons G F; Humphreys S M; Kirk M L; Potts J L; Hockaday T D
Adipose tissue metabolism in obesity: lipase action in vivo before and after a mixed meal.
Metabolism: clinical and experimental 1992;41(3):264-72.
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1991: Frayn K N; Coppack S W; Humphreys S M
Glycerol and lactate uptake in human forearm.
Metabolism: clinical and experimental 1991;40(12):1317-9.
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1991: Potts J L; Fisher R M; Humphreys S M; Coppack S W; Gibbons G F; Frayn K N
Peripheral triacylglycerol extraction in the fasting and post-prandial states.
Clinical science (London, England : 1979) 1991;81(5):621-6.
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1991: Potts J L; Fisher R M; Humphreys S M; Coppack S W; Gibbons G F; Frayn K N
Chylomicrons are the preferred substrate for lipoprotein lipase in vivo.
Biochemical Society transactions 1991;19(3):314S.
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1990: Humphreys S M; Fisher R M; Frayn K N
Micro-method for measurement of sub-nanomole amounts of triacylglycerol.
Annals of clinical biochemistry 1990;27 ( Pt 6)():597-8.
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1990: Coppack S W; Fisher R M; Gibbons G F; Humphreys S M; McDonough M J; Potts J L; Frayn K N
Postprandial substrate deposition in human forearm and adipose tissues in vivo.
Clinical science (London, England : 1979) 1990;79(4):339-48.
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1990: Frayn K N; Coppack S W; Walsh P E; Butterworth H C; Humphreys S M; Pedrosa H C
Metabolic responses of forearm and adipose tissues to acute ethanol ingestion.
Metabolism: clinical and experimental 1990;39(9):958-66.
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1990: Clark M L; Humphreys S M; Frayn K N
Stability of plasma glucose during storage.
Annals of clinical biochemistry 1990;27 ( Pt 4)():373-7.
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1990: Coppack S W; Frayn K N; Humphreys S M; Whyte P L; Hockaday T D
Arteriovenous differences across human adipose and forearm tissues after overnight fast.
Metabolism: clinical and experimental 1990;39(4):384-90.
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1989: Coppack S W; Frayn K N; Humphreys S M; Dhar H; Hockaday T D
Effects of insulin on human adipose tissue metabolism in vivo.
Clinical science (London, England : 1979) 1989;77(6):663-70.
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1989: Frayn K N; Coppack S W; Humphreys S M
Possible importance of glycogen in human adipose tissue.
Biochemical Society transactions 1989;17(6):1091.
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1989: Frayn K N; Coppack S W; Humphreys S M; Whyte P L
Metabolic characteristics of human adipose tissue in vivo.
Clinical science (London, England : 1979) 1989;76(5):509-16.
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1988: Humphreys S M; Frayn K N
Micro-method for preparing perchloric extracts of blood.
Clinical chemistry 1988;34(8):1657.
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