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Li-Wei Hung

Research Profile

Procedures

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Mycobacterium tuberculosis

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Amino Acid Sequences

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Thomas C Terwilliger; Randy J Read; Paul D Adams; Pavel V Afonine; Axel T Brunger; Ralf W Grosse-Kunstleve; Li-Wei Hung
Improved crystallographic models through iterated local density-guided model deformation and reciprocal-space refinement.
Heungbok Kim; Juthamas Kositsawat; Justin K M Roberts; Thomas C Terwilliger; Cecelia Webster; Li-Wei Hung; Chang-Yub Kim
Enhancement of crystallization with nucleotide ligands identified by dye-ligand affinity chromatography.
Paul D Adams; Pavel V Afonine; Gábor Bunkóczi; Vincent B Chen; Nathaniel Echols; Ralf W Grosse Kunstleve; Jeffrey J Headd; Li-Wei Hung; Swati Jain; Gary Kapral; Airlie J McCoy; Nigel W Moriarty; Robert D Oeffner; Randy J Read; David C Richardson; Jane S Richardson; Thomas C Terwilliger; Peter H Zwart
The Phenix software for automated determination of macromolecular structures.

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All Publications

2012: Thomas C Terwilliger; Randy J Read; Paul D Adams; Pavel V Afonine; Axel T Brunger; Ralf W Grosse-Kunstleve; Li-Wei Hung
Improved crystallographic models through iterated local density-guided model deformation and reciprocal-space refinement.
Acta crystallographica. Section D, Biological crystallography 2012;68(Pt 7):861-70.
2012: Heungbok Kim; Juthamas Kositsawat; Justin K M Roberts; Thomas C Terwilliger; Cecelia Webster; Li-Wei Hung; Chang-Yub Kim
Enhancement of crystallization with nucleotide ligands identified by dye-ligand affinity chromatography.
Journal of structural and functional genomics 2012;13(2):71-9.
2011: Paul D Adams; Pavel V Afonine; Gábor Bunkóczi; Vincent B Chen; Nathaniel Echols; Ralf W Grosse Kunstleve; Jeffrey J Headd; Li-Wei Hung; Swati Jain; Gary Kapral; Airlie J McCoy; Nigel W Moriarty; Robert D Oeffner; Randy J Read; David C Richardson; Jane S Richardson; Thomas C Terwilliger; Peter H Zwart
The Phenix software for automated determination of macromolecular structures.
Methods (San Diego, Calif.) 2011;55(1):94-106.
2011: Jiang Yin; Minmin Yu; Emily Z Alipio Lyon; Chang-Yub Kim; Heungbok Kim; Katherine Bateman; Craig Garen; Jeff Habel; Li-Wei Hung; Michael N G James
Expression, purification and preliminary crystallographic analysis of O-acetylhomoserine sulfhydrylase from Mycobacterium tuberculosis.
Acta crystallographica. Section F, Structural biology and crystallization communications 2011;67(Pt 8):959-63.
2010: Jeff E Habel; Evan H Bursey; Beom-Seop Rho; Chang-Yub Kim; Brent W Segelke; Bernhard Rupp; Min S Park; Thomas C Terwilliger; Li-Wei Hung
Structure of Rv1848 (UreA), the Mycobacterium tuberculosis urease gamma subunit.
Acta crystallographica. Section F, Structural biology and crystallization communications 2010;66(Pt 7):781-6.
2010: Paul D Adams; Pavel V Afonine; Gábor Bunkóczi; Vincent B Chen; Ian W Davis; Nathaniel Echols; Jeffrey J Headd; Li-Wei Hung; Gary Kapral; Ralf W Grosse-Kunstleve; Airlie J McCoy; Nigel W Moriarty; Robert Oeffner; Randy J Read; David C Richardson; Jane S Richardson; Thomas C Terwilliger; Peter H Zwart
PHENIX: a comprehensive Python-based system for macromolecular structure solution.
Acta crystallographica. Section D, Biological crystallography 2010;66(Pt 2):213-21.
2009: Chang-Yub Kim; Cecelia Webster; Justin K M Roberts; Jin Ho Moon; Emily Z Alipio Lyon; Heungbok Kim; Minmin Yu; Li-Wei Hung; Thomas C Terwilliger
Analysis of nucleoside-binding proteins by ligand-specific elution from dye resin: application to Mycobacterium tuberculosis aldehyde dehydrogenases.
Journal of structural and functional genomics 2009;10(4):291-301.
2009: Thomas C Terwilliger; Paul D Adams; Randy J Read; Airlie J McCoy; Nigel W Moriarty; Ralf W Grosse-Kunstleve; Pavel V Afonine; Peter H Zwart; Li-Wei Hung
Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard.
Acta crystallographica. Section D, Biological crystallography 2009;65(Pt 6):582-601.
2008: Thomas C Terwilliger; Ralf W Grosse-Kunstleve; Pavel V Afonine; Nigel W Moriarty; Paul D Adams; Randy J Read; Peter H Zwart; Li-Wei Hung
Iterative-build OMIT maps: map improvement by iterative model building and refinement without model bias.
Acta crystallographica. Section D, Biological crystallography 2008;64(Pt 5):515-24.
2008: Peter H Zwart; Pavel V Afonine; Ralf W Grosse-Kunstleve; Li-Wei Hung; Thomas R Ioerger; Airlie J McCoy; Erik McKee; Nigel W Moriarty; Randy J Read; James C Sacchettini; Nicholas K Sauter; Laurent C Storoni; Thomas C Terwilliger; Paul D Adams
Automated structure solution with the PHENIX suite.
Methods in molecular biology (Clifton, N.J.) 2008;426():419-35.
2008: Thomas C Terwilliger; Ralf W Grosse-Kunstleve; Pavel V Afonine; Nigel W Moriarty; Peter H Zwart; Li-Wei Hung; Randy J Read; Paul D Adams
Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard.
Acta crystallographica. Section D, Biological crystallography 2008;64(Pt 1):61-9.
2007: Natalia Friedland; Timothy R Mack; Minmin Yu; Li-Wei Hung; Thomas C Terwilliger; Geoffrey S Waldo; Ann M Stock
Domain orientation in the inactive response regulator Mycobacterium tuberculosis MtrA provides a barrier to activation.
Biochemistry 2007;46(23):6733-43.
2007: A C Murillo; H Y Li; Thomas Alber; Edward N Baker; James M Berger; Leonid T Cherney; M M Cherney; Yoon Song Cho; David Eisenberg; Craig Garen; Celia W Goulding; Li-Wei Hung; Thomas R Ioerger; William R. Jacobs Jr.; Michael N G James; C Kim; I Krieger; J S Lott; R Sankaranarayanan; Brent W Segelke; Thomas C Terwilliger; F Wang; S Wang; James C Sacchettini
High throughput crystallography of TB drug targets.
Infectious disorders drug targets 2007;7(2):127-39.
2007: Thomas C Terwilliger; Ralf W Grosse-Kunstleve; Pavel V Afonine; Paul D Adams; Nigel W Moriarty; Peter H Zwart; Randy J Read; Dusan Turk; Li-Wei Hung
Interpretation of ensembles created by multiple iterative rebuilding of macromolecular models.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 5):597-610.
2006: Evan H Bursey; Chang-Yub Kim; Minmin Yu; Thomas C Terwilliger; Li-Wei Hung
An automated high-throughput screening method for the identification of high-yield, soluble protein variants using cell-free expression and systematic truncation.
Journal of structural and functional genomics 2006;7(3-4):139-47.
2006: Beom-Seop Rho; Li-Wei Hung; James M Holton; Dominico Vigil; Su-Il Kim; Min S Park; Thomas C Terwilliger; Jean-Denis Pédelacq
Functional and structural characterization of a thiol peroxidase from Mycobacterium tuberculosis.
Journal of molecular biology 2006;361(5):850-63.
2006: J Rajan Prabu; Subbiah Thamotharan; Jasbeer Singh Khanduja; Emily Zabala Alipio; Chang-Yub Kim; Geoffrey S Waldo; Thomas C Terwilliger; Brent W Segelke; Timothy Lekin; Dominique Toppani; Li-Wei Hung; Minmin Yu; Evan Bursey; K Muniyappa; Nagasuma R Chandra; Mamannamana Vijayan
Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 8):731-4.
2006: Se Bok Jang; Li-Wei Hung; Mi Suk Jeong; Elizabeth L Holbrook; Xiaoying Chen; Douglas H Turner; Stephen R Holbrook
The crystal structure at 1.5 angstroms resolution of an RNA octamer duplex containing tandem G.U basepairs.
Biophysical journal 2006;90(12):4530-7.
2006: Jean-Denis Pédelacq; Beom-Seop Rho; Chang-Yub Kim; Geoffrey S Waldo; Timothy P Lekin; Brent W Segelke; Bernhard Rupp; Li-Wei Hung; Su-Il Kim; Thomas C Terwilliger
Crystal structure of a putative pyridoxine 5'-phosphate oxidase (Rv2607) from Mycobacterium tuberculosis.
Proteins 2006;62(3):563-9.
2005: Simon Li; Neil A Peterson; Min-Young Kim; Chang-Yub Kim; Li-Wei Hung; Minmin Yu; Timothy Lekin; Brent W Segelke; J Shaun Lott; Edward N Baker
Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys peroxiredoxin.
Journal of molecular biology 2005;346(4):1035-46.
2004: Paul D Adams; Kreshna Gopal; Ralf W Grosse-Kunstleve; Li-Wei Hung; Thomas R Ioerger; Airlie J McCoy; Nigel W Moriarty; Reetal K Pai; Randy J Read; Tod D Romo; James C Sacchettini; Nicholas K Sauter; Laurent C Storoni; Thomas C Terwilliger
Recent developments in the PHENIX software for automated crystallographic structure determination.
Journal of synchrotron radiation 2004;11(Pt 1):53-5.
2002: Paul D Adams; Ralf W Grosse-Kunstleve; Li-Wei Hung; Thomas R Ioerger; Airlie J McCoy; Nigel W Moriarty; Randy J Read; James C Sacchettini; Nicholas K Sauter; Thomas C Terwilliger
PHENIX: building new software for automated crystallographic structure determination.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 11):1948-54.
2000: Li-Wei Hung; Elizabeth L Holbrook; Stephen R Holbrook
The crystal structure of the Rev binding element of HIV-1 reveals novel base pairing and conformational variability.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5107-12.
2000: N Khlebtsova; Li-Wei Hung; K Henderson; R Moon; Thomas N Earnest
Expression, crystallization and preliminary X-ray studies of the PDZ domain of Dishevelled protein.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 2):212-4.
1998: Li-Wei Hung; I X Wang; K Nikaido; PQ Liu; GF Ames; Sung-Huo S H Kim
Crystal structure of the ATP-binding subunit of an ABC transporter.
Nature 1998;396(6712):703-7.
1998: Se Bok Jang; Li-Wei Hung; Young-In Chi; Elizabeth L Holbrook; Richard J Carter; Stephen R Holbrook
Structure of an RNA internal loop consisting of tandem C-A+ base pairs.
Biochemistry 1998;37(34):11726-31.
1998: Z Zhang; L Huang; V M Shulmeister; Young-In Chi; Kyeong Kyu Kim; Li-Wei Hung; Antony R Crofts; Edward A Berry; Sung-Huo S H Kim
Electron transfer by domain movement in cytochrome bc1.
Nature 1998;392(6677):677-84.