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Stéphane Hunot

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M Tasselli; S Paillusson; P Aubert; T Chaumette; Pascal Derkinderen; Corinne Huchet-Cadiou; Stéphane Hunot; Aude Lafoux; Y Monnet; michel neunlist
Effects of oral administration of rotenone on gastrointestinal functions in mice.
Kiyoka Kinugawa; Lixia Lu; Ziad Mallat; Yann Monnet; Clotilde Théry; Amaury J Bekaert; Etienne C Hirsch; Stéphane Hunot
MFGE8 does not orchestrate clearance of apoptotic neurons in a mouse model of Parkinson's disease.
Carmen Noelker; Anke Osterloh; Delphine Skrzydelski; Daniel Alvarez Fischer; Minka Breloer; Candan Depboylu; Richard C Dodel; Carmen Henze; Etienne C Hirsch; Stéphane Hunot; Thomas Lescot; Lixia Lu; Patrick P Michel; Lydie Morel; Andreas Hartmann
Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease.

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2013: M Tasselli; S Paillusson; P Aubert; T Chaumette; Pascal Derkinderen; Corinne Huchet-Cadiou; Stéphane Hunot; Aude Lafoux; Y Monnet; michel neunlist
Effects of oral administration of rotenone on gastrointestinal functions in mice.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2013;25(3):e183-93.
2013: Kiyoka Kinugawa; Lixia Lu; Ziad Mallat; Yann Monnet; Clotilde Théry; Amaury J Bekaert; Etienne C Hirsch; Stéphane Hunot
MFGE8 does not orchestrate clearance of apoptotic neurons in a mouse model of Parkinson's disease.
Neurobiology of disease 2013;51():192-201.
2013: Carmen Noelker; Anke Osterloh; Delphine Skrzydelski; Daniel Alvarez Fischer; Minka Breloer; Candan Depboylu; Richard C Dodel; Carmen Henze; Etienne C Hirsch; Stéphane Hunot; Thomas Lescot; Lixia Lu; Patrick P Michel; Lydie Morel; Andreas Hartmann
Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease.
Scientific reports 2013;3():1393.
2012: Estelle Rousselet; Sabine Traver; Timothy S Zheng; Audrey Hild; Etienne C Hirsch; Nathalie Mandjee; Yann Monnet; Aline Perrin; Stéphane Hunot
Tumor necrosis factor-like weak inducer of apoptosis induces astrocyte proliferation through the activation of transforming-growth factor-α/epidermal growth factor receptor signaling pathway.
Molecular pharmacology 2012;82(5):948-57.
2011: William Rostène; Juliette Van Steenwinckel; Emmanuelle Apartis; Nicolas Beaudet; Marc-André Dansereau; David Godefroy; Stéphane Hunot; Stéphane Mélik Parsadaniantz; Annabelle Reaux-Le Goazigo; Philippe Sarret
Neurochemokines: a menage a trois providing new insights on the functions of chemokines in the central nervous system.
Journal of neurochemistry 2011;118(5):680-94.
2011: Francisco Ros-Bernal; Stéphane Hunot; Maria Trinidad Herrero; Sebastien Parnadeau; Jean-Christophe Corvol; Lixia Lu; Daniel Alvarez Fischer; María Angeles Carrillo-de Sauvage; Françoise Saurini; Christiane Coussieu; Kiyoka Kinugawa; Annick Prigent; Günter Höglinger; Michel Hamon; François Tronche; Etienne C Hirsch; Sheela Vyas
Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(16):6632-7.
2011: Carlos Barcia; Gilles J Guillemin; Stéphane Hunot; Fernando Pitossi
Inflammation and Parkinson's disease.
Parkinson's disease 2011;2011():729054.
2010: Etienne C Hirsch; Stéphane Hunot
Pathophysiological involvement of neuroinflammation in various neurological disorders.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(8):897-8.
2010: Carine Karachi; David Grabli; Frédéric A Bernard; Dominique Tandé; Nicolas Wattiez; Hayat Belaid; Eric Bardinet; Annick Prigent; Hans-Peter Nothacker; Stéphane Hunot; Andreas Hartmann; Stéphane Lehéricy; Etienne C Hirsch; Chantal François
Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease.
The Journal of clinical investigation 2010;120(8):2745-54.
2009: Etienne C Hirsch; Stéphane Hunot
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
Lancet neurology 2009;8(4):382-97.
2009: Vanessa Brochard; Béhazine Combadière; Annick Prigent; Yasmina Laouar; Aline Perrin; Virginie Beray-Berthat; Olivia Bonduelle; Daniel Alvarez Fischer; Jacques Callebert; Jean-Marie Launay; Charles Duyckaerts; Richard A Flavell; Etienne C Hirsch; Stéphane Hunot
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.
The Journal of clinical investigation 2009;119(1):182-92.
2008: Julio Salazar; Natalia Mena; Stéphane Hunot; Annick Prigent; Daniel Alvarez Fischer; Miguel Arredondo; Charles Duyckaerts; Veronique Sazdovitch; Lin Zhao; Laura M Garrick; Marco T Nuñez; Michael D Garrick; Rita Raisman-Vozari; Etienne C Hirsch
Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18578-83.
2008: Daniel Alvarez Fischer; Serge Guerreiro; Stéphane Hunot; Françoise Saurini; Marc Marien; Pierre Sokoloff; Etienne C Hirsch; Andreas Hartmann; Patrick P Michel
Modelling Parkinson-like neurodegeneration via osmotic minipump delivery of MPTP and probenecid.
Journal of neurochemistry 2008;107(3):701-11.
2008: Juan Esteban Ferrario; Argelia Rojas-Mayorquin; Marisa Saldaña-Ortega; Cristiane Salum; Margarete Zanardo Gomes; Stéphane Hunot; Rita Raisman-Vozari
Pleiotrophin receptor RPTP-zeta/beta expression is up-regulated by L-DOPA in striatal medium spiny neurons of parkinsonian rats.
Journal of neurochemistry 2008;107(2):443-52.
2007: Günter U Höglinger; Joshua J Breunig; Candan Depboylu; Caroline Rouaux; Patrick P Michel; Daniel Alvarez Fischer; Anne-Laurence Boutillier; James DeGregori; Wolfgang H Oertel; Pasko Rakic; Etienne C Hirsch; Stéphane Hunot
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3585-90.
2005: Etienne C Hirsch; Stéphane Hunot; Andreas Hartmann
Neuroinflammatory processes in Parkinson's disease.
Parkinsonism & related disorders 2005;11 Suppl 1():S9-S15.
2004: Stéphane Hunot; Miquel Vila; Peter Teismann; Roger J Davis; Etienne C Hirsch; Serge Przedborski; Pasko Rakic; Richard A Flavell
JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):665-70.
2003: Andreas Hartmann; Stéphane Hunot; Etienne C Hirsch
Inflammation and dopaminergic neuronal loss in Parkinson's disease: a complex matter.
Experimental neurology 2003;184(2):561-4.
2003: Etienne C Hirsch; T Breidert; Estelle Rousselet; Stéphane Hunot; Andreas Hartmann; Patrick P Michel
The role of glial reaction and inflammation in Parkinson's disease.
Annals of the New York Academy of Sciences 2003;991():214-28.
2003: Peter Teismann; Kim Tieu; Dong-Kug Choi; Du-Chu Wu; Ali Naini; Stéphane Hunot; Miquel Vila; Vernice Jackson-Lewis; Serge Przedborski
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5473-8.
2003: Stéphane Hunot; Etienne C Hirsch
Neuroinflammatory processes in Parkinson's disease.
Annals of neurology 2003;53 Suppl 3():S49-58; discussion S58-60.
2002: Baptiste A Faucheux; Marie-Elise Martin; Carole Beaumont; Stéphane Hunot; JEAN-JACQUES HAUW; Yves Agid; Etienne C Hirsch
Lack of up-regulation of ferritin is associated with sustained iron regulatory protein-1 binding activity in the substantia nigra of patients with Parkinson's disease.
Journal of neurochemistry 2002;83(2):320-30.
2002: Estelle Rousselet; Jacques Callebert; Karine Parain; Chantal Joubert; Stéphane Hunot; Andreas Hartmann; Claude Jacque; Fernando Perez-Diaz; Charles Cohen-Salmon; Jean-Marie Launay; Etienne C Hirsch
Role of TNF-alpha receptors in mice intoxicated with the parkinsonian toxin MPTP.
Experimental neurology 2002;177(1):183-92.
2001: Stéphane Hunot; Richard A Flavell
Apoptosis. Death of a monopoly?
Science (New York, N.Y.) 2001;292(5518):865-6.
2001: Andreas Hartmann; jean-denis troadec; Stéphane Hunot; K Kikly; Baptiste A Faucheux; Annick Mouatt-Prigent; Merle Ruberg; Yves Agid; Etienne C Hirsch
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(7):2247-55.
2000: Tongzhang Zheng; Stéphane Hunot; Keisuke Kuida; T Momoi; A Srinivasan; D W Nicholson; Y Lazebnik; Richard A Flavell
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation.
Nature medicine 2000;6(11):1241-7.
2000: Etienne C Hirsch; Stéphane Hunot; A Hartmann
Mechanism of cell death in experimental models of Parkinson's disease.
Functional neurology 2000;15(4):229-37.
2000: Etienne C Hirsch; Stéphane Hunot
Nitric oxide, glial cells and neuronal degeneration in parkinsonism.
Trends in pharmacological sciences 2000;21(5):163-5.
2000: Andreas Hartmann; Stéphane Hunot; Patrick P Michel; Marie-Paule Muriel; Sheela Vyas; Baptiste A Faucheux; Annick Mouatt-Prigent; H Turmel; A Srinivasan; Merle Ruberg; Gerard I Evan; Yves Agid; Etienne C Hirsch
Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2875-80.
1999: T S Zheng; Stéphane Hunot; Keisuke Kuida; R A Flavell
Caspase knockouts: matters of life and death.
Cell death and differentiation 1999;6(11):1043-53.
1999: Stéphane Hunot; Nathalie Dugas; Baptiste A Faucheux; Andreas Hartmann; M Tardieu; Patrice Debré; Yves Agid; Bernard Dugas; Etienne C Hirsch
FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(9):3440-7.
1999: Etienne C Hirsch; Stéphane Hunot; Baptiste A Faucheux; Yves Agid; Yoshikuni Mizuno; H Mochizuki; William G Tatton; Nadine A Tatton; W C Olanow
Dopaminergic neurons degenerate by apoptosis in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1999;14(2):383-5.
1999: Etienne C Hirsch; Stéphane Hunot; Philippe Damier; Bernard Brugg; Baptiste A Faucheux; Patrick P Michel; Merle Ruberg; Marie-Paule Muriel; Annick Mouatt-Prigent; Yves Agid
Glial cell participation in the degeneration of dopaminergic neurons in Parkinson's disease.
Advances in neurology 1999;80():9-18.
1999: M Gustavo Murer; F Boissiere; Q Yan; Stéphane Hunot; J Villares; Baptiste A Faucheux; Yves Agid; Etienne C Hirsch; Rita Raisman-Vozari
An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease.
Neuroscience 1999;88(4):1015-32.
1998: A Hartmann; Stéphane Hunot; Etienne C Hirsch
CD95 (APO-1/Fas) and Parkinson's disease.
Annals of neurology 1998;44(3):425-6.
1998: Etienne C Hirsch; Stéphane Hunot; Philippe Damier; Baptiste A Faucheux
Glial cells and inflammation in Parkinson's disease: a role in neurodegeneration?
Annals of neurology 1998;44(3 Suppl 1):S115-20.
1997: F Boissière; Stéphane Hunot; Baptiste A Faucheux; Charles Duyckaerts; JEAN-JACQUES HAUW; Yves Agid; Etienne C Hirsch
Nuclear translocation of NF-kappaB in cholinergic neurons of patients with Alzheimer's disease.
Neuroreport 1997;8(13):2849-52.
1997: Merle Ruberg; V France-Lanord; Bernard Brugg; Nathalie Lambeng; Patrick P Michel; P Anglade; Stéphane Hunot; Philippe Damier; Baptiste A Faucheux; Etienne C Hirsch; Yves Agid
[Neuronal death caused by apoptosis in Parkinson disease].
Revue neurologique 1997;153(8-9):499-508.
1997: Stéphane Hunot; Bernard Brugg; Damien Ricard; Patrick P Michel; Marie-Paule Muriel; Merle Ruberg; Baptiste A Faucheux; Yves Agid; Etienne C Hirsch
Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7531-6.
1997: F Boissière; Stéphane Hunot; Baptiste A Faucheux; Louis B Hersh; Yves Agid; Etienne C Hirsch
Trk neurotrophin receptors in cholinergic neurons of patients with Alzheimer's disease.
Dementia and geriatric cognitive disorders 1997;8(1):1-8.
1996: Stéphane Hunot; F Boissière; Baptiste A Faucheux; Bernard Brugg; Annick Mouatt-Prigent; Yves Agid; Etienne C Hirsch
Nitric oxide synthase and neuronal vulnerability in Parkinson's disease.
Neuroscience 1996;72(2):355-63.
1996: Stéphane Hunot; Véronique Bernard; Baptiste A Faucheux; F Boissière; Eric LeGuern; C Brana; P P Gautris; J Guérin; Bertrand Bloch; Yves Agid; Etienne C Hirsch
Glial cell line-derived neurotrophic factor (GDNF) gene expression in the human brain: a post mortem in situ hybridization study with special reference to Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) 1996;103(8-9):1043-52.
1994: F Boissière; Stéphane Hunot; Baptiste A Faucheux; Annick Mouatt-Prigent; Yves Agid; Etienne C Hirsch
High affinity neurotrophin receptors in cholinergic neurons in the human brain.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1994;317(11):997-1003.