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MG Hunter

Research Profile

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Lloyd Czaplewski; J McKeating; C J Craven; Lee D Higgins; V Appay; A Brown; Tim Dudgeon; L A Howard; T Meyers; J Owen; Shilpa Palan; P Tan; G Wilson; N R Woods; Clare Heyworth; BI Lord; D Brotherton; R Christison; S Craig; S Cribbes; R M Edwards; S J Evans; R Gilbert; P Morgan; E Randle; Nichola Schofield; Paul Varley; Julie Fisher; Jonathan P Waltho; MG Hunter
Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants.
M J Clemons; E Marshall; Jan Dürig; K Watanabe; A Howell; D Miles; Helena Earl; J Kiernan; A Griffiths; K Towlson; P DeTakats; Nydia G Testa; M Dougal; MG Hunter; L M Wood; Lloyd Czaplewski; A Millar; TM Dexter; BI Lord
A randomized phase-II study of BB-10010 (macrophage inflammatory protein- 1alpha) in patients with advanced breast cancer receiving 5-fluorouracil, adriamycin, and cyclophosphamide chemotherapy.
E Marshall; A H Howell; R Powles; MG Hunter; M Edwards; L M Wood; Lloyd Czaplewski; R Puttick; Steve Warrington; M Boyce; Nydia G Testa; TM Dexter; BI Lord; A Millar
Clinical effects of human macrophage inflammatory protein-1 alpha MIP-1 alpha (LD78) administration to humans: a phase I study in cancer patients and normal healthy volunteers with the genetically engineered variant, BB-10010.

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All Publications

1999: Lloyd Czaplewski; J McKeating; C J Craven; Lee D Higgins; V Appay; A Brown; Tim Dudgeon; L A Howard; T Meyers; J Owen; Shilpa Palan; P Tan; G Wilson; N R Woods; Clare Heyworth; BI Lord; D Brotherton; R Christison; S Craig; S Cribbes; R M Edwards; S J Evans; R Gilbert; P Morgan; E Randle; Nichola Schofield; Paul Varley; Julie Fisher; Jonathan P Waltho; MG Hunter
Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants.
The Journal of biological chemistry 1999;274(23):16077-84.
1998: M J Clemons; E Marshall; Jan Dürig; K Watanabe; A Howell; D Miles; Helena Earl; J Kiernan; A Griffiths; K Towlson; P DeTakats; Nydia G Testa; M Dougal; MG Hunter; L M Wood; Lloyd Czaplewski; A Millar; TM Dexter; BI Lord
A randomized phase-II study of BB-10010 (macrophage inflammatory protein- 1alpha) in patients with advanced breast cancer receiving 5-fluorouracil, adriamycin, and cyclophosphamide chemotherapy.
Blood 1998;92(5):1532-40.
1998: E Marshall; A H Howell; R Powles; MG Hunter; M Edwards; L M Wood; Lloyd Czaplewski; R Puttick; Steve Warrington; M Boyce; Nydia G Testa; TM Dexter; BI Lord; A Millar
Clinical effects of human macrophage inflammatory protein-1 alpha MIP-1 alpha (LD78) administration to humans: a phase I study in cancer patients and normal healthy volunteers with the genetically engineered variant, BB-10010.
European journal of cancer (Oxford, England : 1990) 1998;34(7):1023-9.
1998: P Jane Owen-Lynch; Lloyd Czaplewski; MG Hunter; Anthony D Whetton
The growth inhibitory role and potential clinical value of macrophage inflammatory protein 1 alpha in myeloid leukaemias.
Leukemia & lymphoma 1998;30(1-2):41-53.
1996: BI Lord; E Marshall; Lorna B Woolford; MG Hunter
BB-10010/MIP-1 alpha in vivo maintains haemopoietic recovery following repeated cycles of sublethal irradiation.
British journal of cancer 1996;74(7):1017-22.
1995: MG Hunter; L Bawden; D Brotherton; S Craig; S Cribbes; Lloyd Czaplewski; TM Dexter; A H Drummond; A H Gearing; C M Heyworth; BI Lord; M McCourt; Paul Varley; L M Wood; R M Edwards; P J Lewis
BB-10010: an active variant of human macrophage inflammatory protein-1 alpha with improved pharmaceutical properties.
Blood 1995;86(12):4400-8.
1995: BI Lord; Lorna B Woolford; L M Wood; Lloyd Czaplewski; M McCourt; MG Hunter; R M Edwards
Mobilization of early hematopoietic progenitor cells with BB-10010: a genetically engineered variant of human macrophage inflammatory protein-1 alpha.
Blood 1995;85(12):3412-5.