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Tony Hunter

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Phenomena

Phosphorylation

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequence

Living Beings

Concepts & Ideas

Molecular Sequence Data

Anatomy

Cell Line

Physiology

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Co-Publications
Name
13
Verma, Inder
12
Joazeiro, Claudio
10
Karin, Michael
7
Noel, Joseph
6
Woodring, Pamela
6
Lu, Kun Ping
6
Meisenhelder, Jill
6
Huang, Han-Kuei
5
Hoekstra, MF
5
Firtel, Richard
5
Ghosh, Sourav
5
Verdecia, Mark
5
Potter, LR
5
Shah, Jameel
4
Sefton, Bartholomew

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Publications

TOP 3
Zhang You-Wei; Brognard John; Coughlin Chris; You Zhongsheng; Dolled-Filhart Marisa; Aslanian Aaron; Manning Gerard; Abraham Robert T; Hunter Tony
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.
Carrano Andrea C; Liu Zheng; Dillin Andrew; Hunter Tony
A conserved ubiquitination pathway determines longevity in response to diet restriction.
Hunter Tony
Tyrosine phosphorylation: thirty years and counting.

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All Publications

2009: Zhang You-Wei; Brognard John; Coughlin Chris; You Zhongsheng; Dolled-Filhart Marisa; Aslanian Aaron; Manning Gerard; Abraham Robert T; Hunter Tony
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress.
Molecular cell 2009;35(4):442-53.
2009: Carrano Andrea C; Liu Zheng; Dillin Andrew; Hunter Tony
A conserved ubiquitination pathway determines longevity in response to diet restriction.
Nature 2009;460(7253):396-9.
2009: Hunter Tony
Tyrosine phosphorylation: thirty years and counting.
Current opinion in cell biology 2009;21(2):140-6.
2009: Copp Jeremy; Manning Gerard; Hunter Tony
TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2.
Cancer research 2009;69(5):1821-7.
2009: Pearson Gray W; Hunter Tony
PI-3 kinase activity is necessary for ERK1/2-induced disruption of mammary epithelial architecture.
Breast cancer research : BCR 2009;11(3):R29.
2009: Smith Jeramiah J; Putta Srikrishna; Zhu Wei; Pao Gerald M; Verma Inder M; Hunter Tony; Bryant Susan V; Gardiner David M; Harkins Timothy T; Voss S Randal
Genic regions of a large salamander genome contain long introns and novel genes.
BMC genomics 2009;10():19.
2009: Monaghan James R; Epp Leonard G; Putta Srikrishna; Page Robert B; Walker John A; Beachy Chris K; Zhu Wei; Pao Gerald M; Verma Inder M; Hunter Tony; Bryant Susan V; Gardiner David M; Harkins Tim T; Voss S Randal
Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration.
BMC biology 2009;7():1.
2008: Hashimoto Toshiaki; Yamauchi Lisa; Hunter Tony; Kikkawa Ushio; Kamada Shinji
Possible involvement of caspase-7 in cell cycle progression at mitosis.
Genes to cells : devoted to molecular & cellular mechanisms 2008;13(6):609-21.
2008: Hunter Tony
Tony Hunter: kinase king. Interview by Ruth Williams.
The Journal of cell biology 2008;181(4):572-3.
2008: Bailis Julie M; Luche Douglas D; Hunter Tony; Forsburg Susan L
Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote s-phase genome stability.
Molecular and cellular biology 2008;28(5):1724-38.
2008: Ghosh Sourav; Marquardt Till; Thaler Joshua P; Carter Nigel; Andrews Shane E; Pfaff Samuel L; Hunter Tony
Instructive role of aPKCzeta subcellular localization in the assembly of adherens junctions in neural progenitors.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(1):335-40.
2008: Hunter T; Sun H
Crosstalk between the SUMO and ubiquitin pathways.
Ernst Schering Foundation symposium proceedings 2008;(1):1-16.
2007: Pearson Gray W; Hunter Tony
Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells.
The Journal of cell biology 2007;179(7):1555-67.
2007: Hunter Tony
The age of crosstalk: phosphorylation, ubiquitination, and beyond.
Molecular cell 2007;28(5):730-8.
2007: You Zhongsheng; Bailis Julie M; Johnson Sam A; Dilworth Stephen M; Hunter Tony
Rapid activation of ATM on DNA flanking double-strand breaks.
Nature cell biology 2007;9(11):1311-8.
2007: Sun Huaiyu; Leverson Joel D; Hunter Tony
Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins.
The EMBO journal 2007;26(18):4102-12.
2007: Johnson Sam A; You Zhongsheng; Hunter Tony
Monitoring ATM kinase activity in living cells.
DNA repair 2007;6(9):1277-84.
2007: Hunter Tony
Treatment for chronic myelogenous leukemia: the long road to imatinib.
The Journal of clinical investigation 2007;117(8):2036-43.
2007: Han E K-H; Leverson J D; McGonigal T; Shah O J; Woods K W; Hunter T; Giranda V L; Luo Y
Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition.
Oncogene 2007;26(38):5655-61.
2007: Zhang Yan; Daum Sebastian; Wildemann Dirk; Zhou Xiao Zhen; Verdecia Mark A; Bowman Marianne E; Lücke Christian; Hunter Tony; Lu Kun-Ping; Fischer Gunter; Noel Joseph P
Structural basis for high-affinity peptide inhibition of human Pin1.
ACS chemical biology 2007;2(5):320-8.
2007: Fang Dexing; Hawke David; Zheng Yanhua; Xia Yan; Meisenhelder Jill; Nika Heinz; Mills Gordon B; Kobayashi Ryuji; Hunter Tony; Lu Zhimin
Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity.
The Journal of biological chemistry 2007;282(15):11221-9.
2007: Hunter T; Simon J
A not so brief history of the Oncogene Meeting and its cartoons.
Oncogene 2007;26(9):1260-7.
2007: Bozulic Lana; Morin Pier; Hunter Tony; Hemmings Brian A
Meeting report: targeting the kinome--20 years of tyrosine kinase inhibitor research in Basel.
Science's STKE : signal transduction knowledge environment 2007;2007(374):pe8.
2007: Xia Yan; Wang Ji; Liu Ta-Jen; Yung W K Alfred; Hunter Tony; Lu Zhimin
c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis.
Molecular cell 2007;25(2):219-32.
2007: Xia Yan; Wang Ji; Xu Shuichan; Johnson Gary L; Hunter Tony; Lu Zhimin
MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress.
Molecular and cellular biology 2007;27(2):510-7.
2006: Ghosh Sourav; Tergaonkar Vinay; Rothlin Carla V; Correa Ricardo G; Bottero Virginie; Bist Pradeep; Verma Inder M; Hunter Tony
Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival.
Cancer cell 2006;10(3):215-26.
2006: Shah O Jameel; Hunter Tony
Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis.
Molecular and cellular biology 2006;26(17):6425-34.
2006: Joazeiro Claudio A P; Anderson Kenneth C; Hunter Tony
Proteasome inhibitor drugs on the rise.
Cancer research 2006;66(16):7840-2.
2006: Wolff Suzanne; Ma Hui; Burch Denise; Maciel Gustavo A; Hunter Tony; Dillin Andrew
SMK-1, an essential regulator of DAF-16-mediated longevity.
Cell 2006;124(5):1039-53.
2006: Petersen Paris; Chou Danny M; You Zhongsheng; Hunter Tony; Walter Johannes C; Walter Gernot
Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint.
Molecular and cellular biology 2006;26(5):1997-2011.
2006: Wang Zhiyong; Qi Chao; Krones Anna; Woodring Pamela; Zhu Xiaoyan; Reddy Janardan K; Evans Ronald M; Rosenfeld Michael G; Hunter Tony
Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance.
Cell metabolism 2006;3(2):111-22.
2006: Zhang You-Wei; Hunter Tony; Abraham Robert T
Turning the replication checkpoint on and off.
Cell cycle (Georgetown, Tex.) 2006;5(2):125-8.
2005: Hunter Tony; Schulman Howard
CaMKII structure--an elegant design.
Cell 2005;123(5):765-7.
2005: Kamada Shinji; Kikkawa Ushio; Tsujimoto Yoshihide; Hunter Tony
A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association.
Molecular and cellular biology 2005;25(21):9469-77.
2005: Huang Han-Kuei; Bailis Julie M; Leverson Joel D; Gómez Eliana B; Forsburg Susan L; Hunter Tony
Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.
Molecular and cellular biology 2005;25(20):9000-15.
2005: Watanabe Nobumoto; Arai Harumi; Iwasaki Jun-Ichi; Shiina Masaaki; Ogata Kazuhiro; Hunter Tony; Osada Hiroyuki
Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(33):11663-8.
2005: You Zhongsheng; Chahwan Charly; Bailis Julie; Hunter Tony; Russell Paul
ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1.
Molecular and cellular biology 2005;25(13):5363-79.
2005: Wang Xuelu; Li Xiaoqing; Meisenhelder Jill; Hunter Tony; Yoshida Shigeo; Asami Tadao; Chory Joanne
Autoregulation and homodimerization are involved in the activation of the plant steroid receptor BRI1.
Developmental cell 2005;8(6):855-65.
2005: Takagi Yuichiro; Masuda Claudio A; Chang Wei-Hau; Komori Hirofumi; Wang Dong; Hunter Tony; Joazeiro Claudio A P; Kornberg Roger D
Ubiquitin ligase activity of TFIIH and the transcriptional response to DNA damage.
Molecular cell 2005;18(2):237-43.
2005: Marquardt Till; Shirasaki Ryuichi; Ghosh Sourav; Andrews Shane E; Carter Nigel; Hunter Tony; Pfaff Samuel L
Coexpressed EphA receptors and ephrin-A ligands mediate opposing actions on growth cone navigation from distinct membrane domains.
Cell 2005;121(1):127-39.
2005: Woodring Pamela J; Hunter Tony; Wang Jean Y J
Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition.
The Journal of biological chemistry 2005;280(11):10318-25.
2005: Papin Jason A; Hunter Tony; Palsson Bernhard O; Subramaniam Shankar
Reconstruction of cellular signalling networks and analysis of their properties.
Nature reviews. Molecular cell biology 2005;6(2):99-111.
2005: Johnson Sam A; Hunter Tony
Kinomics: methods for deciphering the kinome.
Nature methods 2005;2(1):17-25.
2005: Shah O Jameel; Hunter Tony
Tuberous sclerosis and insulin resistance. Unlikely bedfellows reveal a TORrid affair.
Cell cycle (Georgetown, Tex.) 2005;4(1):46-51.
2005: Kamada Shinji; Kikkawa Ushio; Tsujimoto Yoshihide; Hunter Tony
Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s).
The Journal of biological chemistry 2005;280(2):857-60.
2004: York John D; Hunter Tony
Signal transduction. Unexpected mediators of protein phosphorylation.
Science (New York, N.Y.) 2004;306(5704):2053-5.
2004: Grabbe Caroline; Zervas Christos G; Hunter Tony; Brown Nicholas H; Palmer Ruth H
Focal adhesion kinase is not required for integrin function or viability in Drosophila.
Development (Cambridge, England) 2004;131(23):5795-805.
2004: Shah O Jameel; Wang Zhiyong; Hunter Tony
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies.
Current biology : CB 2004;14(18):1650-6.
2004: Johnson Sam A; Hunter Tony
Phosphoproteomics finds its timing.
Nature biotechnology 2004;22(9):1093-4.
2004: Caenepeel Sean; Charydczak Glen; Sudarsanam Sucha; Hunter Tony; Manning Gerard
The mouse kinome: discovery and comparative genomics of all mouse protein kinases.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11707-12.
2004: Alonso Andres; Sasin Joanna; Bottini Nunzio; Friedberg Ilan; Friedberg Iddo; Osterman Andrei; Godzik Adam; Hunter Tony; Dixon Jack; Mustelin Tomas
Protein tyrosine phosphatases in the human genome.
Cell 2004;117(6):699-711.
2004: Woodring Pamela J; Meisenhelder Jill; Johnson Sam A; Zhou Guo-Lei; Field Jeffrey; Shah Kavita; Bladt Friedhelm; Pawson Tony; Niki Masaru; Pandolfi Pier Paolo; Wang Jean Y J; Hunter Tony
c-Abl phosphorylates Dok1 to promote filopodia during cell spreading.
The Journal of cell biology 2004;165(4):493-503.
2004: Lu Zhimin; Hunter Tony
Wnt-independent beta-catenin transactivation in tumor development.
Cell cycle (Georgetown, Tex.) 2004;3(5):571-3.
2004: Shah O Jameel; Hunter Tony
Critical role of T-loop and H-motif phosphorylation in the regulation of S6 kinase 1 by the tuberous sclerosis complex.
The Journal of biological chemistry 2004;279(20):20816-23.
2004: Watanabe Nobumoto; Arai Harumi; Nishihara Yoshifumi; Taniguchi Makoto; Watanabe Naoko; Hunter Tony; Osada Hiroyuki
M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(13):4419-24.
2004: Hunter Tony; Eckhart Walter
The discovery of tyrosine phosphorylation: it's all in the buffer!
Cell 2004;116(2 Suppl):S35-9, 1 p following S48.
2004: Fukunaga Rikiro; Hunter Tony
Identification of MAPK substrates by expression screening with solid-phase phosphorylation.
Methods in molecular biology (Clifton, N.J.) 2004;250():211-36.
2003: Lu Zhimin; Ghosh Sourav; Wang Zhiyong; Hunter Tony
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.
Cancer cell 2003;4(6):499-515.
2003: Lorén Christina E; Englund Camilla; Grabbe Caroline; Hallberg Bengt; Hunter Tony; Palmer Ruth H
A crucial role for the Anaplastic lymphoma kinase receptor tyrosine kinase in gut development in Drosophila melanogaster.
EMBO reports 2003;4(8):781-6.
2003: Liou Yih-Cherng; Sun Anyang; Ryo Akihide; Zhou Xiao Zhen; Yu Zhao-Xue; Huang Han-Kuei; Uchida Takafumi; Bronson Roderick; Bing Guoying; Li Xiaojiang; Hunter Tony; Lu Kun Ping
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.
Nature 2003;424(6948):556-61.
2003: Sonnenburg Erica Dutil; Bilwes Alexandrine; Hunter Tony; Noel Joseph P
The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region.
Biochemistry 2003;42(26):7904-14.
2003: Woodring Pamela J; Hunter Tony; Wang Jean Y J
Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases.
Journal of cell science 2003;116(Pt 13):2613-26.
2003: O'Connell Matthew J; Krien Michael J E; Hunter Tony
Never say never. The NIMA-related protein kinases in mitotic control.
Trends in cell biology 2003;13(5):221-8.
2003: Shah O Jameel; Ghosh Sourav; Hunter Tony
Mitotic regulation of ribosomal S6 kinase 1 involves Ser/Thr, Pro phosphorylation of consensus and non-consensus sites by Cdc2.
The Journal of biological chemistry 2003;278(18):16433-42.
2003: Xia Yan; Pao Gerald M; Chen Hong-Wu; Verma Inder M; Hunter Tony
Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein.
The Journal of biological chemistry 2003;278(7):5255-63.
2003: Uchida Takafumi; Takamiya Mari; Takahashi Morito; Miyashita Hitoshi; Ikeda Hisafumi; Terada Toru; Matsuo Yo; Shirouzu Mikako; Yokoyama Shigeyuki; Fujimori Fumihiro; Hunter Tony
Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation.
Chemistry & biology 2003;10(1):15-24.
2003: Verdecia Mark A; Joazeiro Claudio A P; Wells Nicholas J; Ferrer Jean-Luc; Bowman Marianne E; Hunter Tony; Noel Joseph P
Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase.
Molecular cell 2003;11(1):249-59.
2002: Gilman Alfred G; Simon Melvin I; Bourne Henry R; Harris Bruce A; Long Rochelle; Ross Elliott M; Stull James T; Taussig Ronald; Bourne Henry R; Arkin Adam P; Cobb Melanie H; Cyster Jason G; Devreotes Peter N; Ferrell James E; Fruman David; Gold Michael; Weiss Arthur; Stull James T; Berridge Michael J; Cantley Lewis C; Catterall William A; Coughlin Shaun R; Olson Eric N; Smith Temple F; Brugge Joan S; Botstein David; Dixon Jack E; Hunter Tony; Lefkowitz Robert J; Pawson Anthony J; Sternberg Paul W; Varmus Harold; Subramaniam Shankar; Sinkovits Robert S; Li Joshua; Mock Dennis; Ning Yuhong; Saunders Brian; Sternweis Paul C; Hilgemann Donald; Scheuermann Richard H; DeCamp Dianne; Hsueh Robert; Lin Keng-Mean; Ni Yan; Seaman William E; Simpson Paul C; O'Connell Timothy D; Roach Tamara; Simon Melvin I; Choi Sangdun; Eversole-Cire Pamela; Fraser Iain; Mumby Marc C; Zhao Yingming; Brekken Deirdre; Shu Hongjun; Meyer Tobias; Chandy Grischa; Heo Won Do; Liou Jen; O'Rourke Nancy; Verghese Mary; Mumby Susanne M; Han Heping; Brown H Alex; Forrester Jeffrey S; Ivanova Pavlina; Milne Stephen B; Casey Patrick J; Harden T Kendall; Arkin Adam P; Doyle John; Gray Martha L; Meyer Tobias; Michnick Stephen; Schmidt Martin A; Toner Mehmet; Tsien Roger Y; Natarajan Madhusudan; Ranganathan Rama; Sambrano Gilberto R;
Overview of the Alliance for Cellular Signaling.
Nature 2002;420(6916):703-6.
2002: Manning G; Whyte D B; Martinez R; Hunter T; Sudarsanam S
The protein kinase complement of the human genome.
Science (New York, N.Y.) 2002;298(5600):1912-34.
2002: Manning Gerard; Plowman Gregory D; Hunter Tony; Sudarsanam Sucha
Evolution of protein kinase signaling from yeast to man.
Trends in biochemical sciences 2002;27(10):514-20.
2002: Carter Nigel; Nakamoto Tetsuya; Hirai Hisamaru; Hunter Tony
EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas).
Nature cell biology 2002;4(8):565-73.
2002: Hunter Tony
Tyrosine phosphorylation in cell signaling and disease.
The Keio journal of medicine 2002;51(2):61-71.
2002: Mollinari Cristiana; Kleman Jean-Philippe; Jiang Wei; Schoehn Guy; Hunter Tony; Margolis Robert L
PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone.
The Journal of cell biology 2002;157(7):1175-86.
2002: Lu Zhimin; Xu Shuichan; Joazeiro Claudio; Cobb Melanie H; Hunter Tony
The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2.
Molecular cell 2002;9(5):945-56.
2002: Asahara Hiroshi; Tartare-Deckert Sophie; Nakagawa Takeya; Ikehara Tsuyoshi; Hirose Fumiko; Hunter Tony; Ito Takashi; Montminy Marc
Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro.
Molecular and cellular biology 2002;22(9):2974-83.
2002: Leverson Joel D; Huang Han-kuei; Forsburg Susan L; Hunter Tony
The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis.
Molecular biology of the cell 2002;13(4):1132-43.
2002: Woodring Pamela J; Litwack E David; O'Leary Dennis D M; Lucero Ginger R; Wang Jean Y J; Hunter Tony
Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension.
The Journal of cell biology 2002;156(5):879-92.
2002: Fang Deyu; Elly Chris; Gao Baixue; Fang Nan; Altman Yoav; Joazeiro Claudio; Hunter Tony; Copeland Neal; Jenkins Nancy; Liu Yun-Cai
Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.
Nature immunology 2002;3(3):281-7.
2002: Liou Yih-Cherng; Ryo Akihide; Huang Han-Kuei; Lu Pei-Jung; Bronson Roderick; Fujimori Fumihiro; Uchida Takafumi; Hunter Tony; Lu Kun Ping
Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1335-40.
2002: Mustelin Tomas; Hunter Tony
Meeting at mitosis: cell cycle-specific regulation of c-Src by RPTPalpha.
Science's STKE : signal transduction knowledge environment 2002;2002(115):pe3.
2001: Buck M; Zhang L; Halasz N A; Hunter T; Chojkier M
Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha.
The EMBO journal 2001;20(23):6712-23.
2001: Huang H K; Forsburg S L; John U P; O'Connell M J; Hunter T
Isolation and characterization of the Pin1/Ess1p homologue in Schizosaccharomyces pombe.
Journal of cell science 2001;114(Pt 20):3779-88.
2001: Buck M; Poli V; Hunter T; Chojkier M
C/EBPbeta phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival.
Molecular cell 2001;8(4):807-16.
2001: Jiang B H; Jiang G; Zheng J Z; Lu Z; Hunter T; Vogt P K
Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001;12(7):363-9.
2001: Woodring P J; Hunter T; Wang J Y
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
The Journal of biological chemistry 2001;276(29):27104-10.
2001: Lorén C E; Scully A; Grabbe C; Edeen P T; Thomas J; McKeown M; Hunter T; Palmer R H
Identification and characterization of DAlk: a novel Drosophila melanogaster RTK which drives ERK activation in vivo.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(6):531-44.
2001: Lu Z; Jiang G; Blume-Jensen P; Hunter T
Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase.
Molecular and cellular biology 2001;21(12):4016-31.
2001: Meisenhelder J; Hunter T; van der Geer P
Phosphopeptide mapping and identification of phosphorylation sites.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2001;Chapter 13():Unit13.9.
2001: Meisenhelder J; Hunter T; van der Geer P
Phosphopeptide mapping and identification of phosphorylation sites.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2001;Chapter 18():Unit 18.9.
2001: Blume-Jensen P; Hunter T
Oncogenic kinase signalling.
Nature 2001;411(6835):355-65.
2001: Hauck C R; Hunter T; Schlaepfer D D
The v-Src SH3 domain facilitates a cell adhesion-independent association with focal adhesion kinase.
The Journal of biological chemistry 2001;276(21):17653-62.
2001: Ruffner H; Joazeiro C A; Hemmati D; Hunter T; Verma I M
Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):5134-9.
2001: Early A; Gamper M; Moniakis J; Kim E; Hunter T; Williams J G; Firtel R A
Protein tyrosine phosphatase PTP1 negatively regulates Dictyostelium STATa and is required for proper cell-type proportioning.
Developmental biology 2001;232(1):233-45.
2001: Moniakis J; Funamoto S; Fukuzawa M; Meisenhelder J; Araki T; Abe T; Meili R; Hunter T; Williams J; Firtel R A
An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway.
Genes & development 2001;15(6):687-98.
2001: Potter L R; Hunter T
Guanylyl cyclase-linked natriuretic peptide receptors: structure and regulation.
The Journal of biological chemistry 2001;276(9):6057-60.
2001: Tertoolen L G; Blanchetot C; Jiang G; Overvoorde J; Gadella T W; Hunter T; den Hertog J
Dimerization of receptor protein-tyrosine phosphatase alpha in living cells.
BMC cell biology 2001;2():8.
2001: Blume-Jensen P; Hunter T
Two-dimensional phosphoamino acid analysis.
Methods in molecular biology (Clifton, N.J.) 2001;124():49-65.
2000: Sudol M; Hunter T
NeW wrinkles for an old domain.
Cell 2000;103(7):1001-4.
2000: Hefner Y; Borsch-Haubold A G; Murakami M; Wilde J I; Pasquet S; Schieltz D; Ghomashchi F; Yates J R; Armstrong C G; Paterson A; Cohen P; Fukunaga R; Hunter T; Kudo I; Watson S P; Gelb M H
Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases.
The Journal of biological chemistry 2000;275(48):37542-51.
2000: Qiu L; Joazeiro C; Fang N; Wang H Y; Elly C; Altman Y; Fang D; Hunter T; Liu Y C
Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase.
The Journal of biological chemistry 2000;275(46):35734-7.
2000: Potter L R; Hunter T
Activation of protein kinase C stimulates the dephosphorylation of natriuretic peptide receptor-B at a single serine residue: a possible mechanism of heterologous desensitization.
The Journal of biological chemistry 2000;275(40):31099-106.
2000: Joazeiro C A; Hunter T
Biochemistry. Ubiquitination--more than two to tango.
Science (New York, N.Y.) 2000;289(5487):2061-2.
2000: Huang H k; Joazeiro C A; Bonfoco E; Kamada S; Leverson J D; Hunter T
The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7.
The Journal of biological chemistry 2000;275(35):26661-4.
2000: Friedrichsen D M; Joazeiro C A; Li J; Hunter T; Chory J
Brassinosteroid-insensitive-1 is a ubiquitously expressed leucine-rich repeat receptor serine/threonine kinase.
Plant physiology 2000;123(4):1247-56.
2000: Verdecia M A; Bowman M E; Lu K P; Hunter T; Noel J P
Structural basis for phosphoserine-proline recognition by group IV WW domains.
Nature structural biology 2000;7(8):639-43.
2000: Jiang G; den Hertog J; Hunter T
Receptor-like protein tyrosine phosphatase alpha homodimerizes on the cell surface.
Molecular and cellular biology 2000;20(16):5917-29.
2000: Leverson J D; Joazeiro C A; Page A M; Huang H k; Hieter P; Hunter T
The APC11 RING-H2 finger mediates E2-dependent ubiquitination.
Molecular biology of the cell 2000;11(7):2315-25.
2000: Verdecia M A; Huang H; Dutil E; Kaiser D A; Hunter T; Noel J P
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement.
Nature structural biology 2000;7(7):602-8.
2000: Mal A; Chattopadhyay D; Ghosh M K; Poon R Y; Hunter T; Harter M L
p21 and retinoblastoma protein control the absence of DNA replication in terminally differentiated muscle cells.
The Journal of cell biology 2000;149(2):281-92.
2000: Xu S; Huang H K; Kaiser P; Latterich M; Hunter T
Phosphorylation and spindle pole body localization of the Cdc15p mitotic regulatory protein kinase in budding yeast.
Current biology : CB 2000;10(6):329-32.
2000: Cassman M; Hunter T; Pawson T
Proteins suggest form of their own database.
Nature 2000;403(6770):591-2.
2000: Pao G M; Janknecht R; Ruffner H; Hunter T; Verma I M
CBP/p300 interact with and function as transcriptional coactivators of BRCA1.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(3):1020-5.
2000: Blume-Jensen P; Jiang G; Hyman R; Lee K F; O'Gorman S; Hunter T
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility.
Nature genetics 2000;24(2):157-62.
2000: Hunter T
Signaling--2000 and beyond.
Cell 2000;100(1):113-27.
1999: Pearson K L; Hunter T; Janknecht R
Activation of Smad1-mediated transcription by p300/CBP.
Biochimica et biophysica acta 1999;1489(2-3):354-64.
1999: Buck M; Poli V; van der Geer P; Chojkier M; Hunter T
Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBP beta is required for hepatocyte proliferation induced by TGF alpha.
Molecular cell 1999;4(6):1087-92.
1999: Palmer R H; Fessler L I; Edeen P T; Madigan S J; McKeown M; Hunter T
DFak56 is a novel Drosophila melanogaster focal adhesion kinase.
The Journal of biological chemistry 1999;274(50):35621-9.
1999: Potter L R; Hunter T
Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B.
Methods (San Diego, Calif.) 1999;19(4):506-20.
1999: Plowman G D; Sudarsanam S; Bingham J; Whyte D; Hunter T
The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13603-10.
1999: Jiang G; den Hertog J; Su J; Noel J; Sap J; Hunter T
Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alpha.
Nature 1999;401(6753):606-10.
1999: Jiang W; McDonald D; Hope T J; Hunter T
Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication.
The EMBO journal 1999;18(20):5703-13.
1999: Joazeiro C A; Wing S S; Huang H; Leverson J D; Hunter T; Liu Y C
The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase.
Science (New York, N.Y.) 1999;286(5438):309-12.
1999: Zheng C; Xiang J; Hunter T; Lin A
The JNKK2-JNK1 fusion protein acts as a constitutively active c-Jun kinase that stimulates c-Jun transcription activity.
The Journal of biological chemistry 1999;274(41):28966-71.
1999: Wells N J; Watanabe N; Tokusumi T; Jiang W; Verdecia M A; Hunter T
The C-terminal domain of the Cdc2 inhibitory kinase Myt1 interacts with Cdc2 complexes and is required for inhibition of G(2)/M progression.
Journal of cell science 1999;112 ( Pt 19)():3361-71.
1999: Jiang G; Hunter T
Receptor signaling: when dimerization is not enough.
Current biology : CB 1999;9(15):R568-71.
1999: Ruffner H; Jiang W; Craig A G; Hunter T; Verma I M
BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site.
Molecular and cellular biology 1999;19(7):4843-54.
1999: Biggs W H; Meisenhelder J; Hunter T; Cavenee W K; Arden K C
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7421-6.
1999: Potter L R; Hunter T
A constitutively "phosphorylated" guanylyl cyclase-linked atrial natriuretic peptide receptor mutant is resistant to desensitization.
Molecular biology of the cell 1999;10(6):1811-20.
1999: Jiang W; Wells N J; Hunter T
Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6193-8.
1999: Janknecht R; Hunter T
Nuclear fusion of signaling pathways.
Science (New York, N.Y.) 1999;284(5413):443-4.
1999: Gamper M; Kim E; Howard P K; Ma H; Hunter T; Firtel R A
Regulation of Dictyostelium protein-tyrosine phosphatase-3 (PTP3) through osmotic shock and stress stimulation and identification of pp130 as a PTP3 substrate.
The Journal of biological chemistry 1999;274(17):12129-38.
1999: Sekiguchi T; Nishimoto T; Hunter T
Overexpression of D-type cyclins, E2F-1, SV40 large T antigen and HPV16 E7 rescue cell cycle arrest of tsBN462 cells caused by the CCG1/TAF(II)250 mutation.
Oncogene 1999;18(10):1797-806.
1999: Pyronnet S; Imataka H; Gingras A C; Fukunaga R; Hunter T; Sonenberg N
Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.
The EMBO journal 1999;18(1):270-9.
1998: Jiang W; Jimenez G; Wells N J; Hope T J; Wahl G M; Hunter T; Fukunaga R
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis.
Molecular cell 1998;2(6):877-85.
1998: Sieg D J; Ilic D; Jones K C; Damsky C H; Hunter T; Schlaepfer D D
Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.
The EMBO journal 1998;17(20):5933-47.
1998: Janknecht R; Wells N J; Hunter T
TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300.
Genes & development 1998;12(14):2114-9.
1998: Herdegen T; Claret F X; Kallunki T; Martin-Villalba A; Winter C; Hunter T; Karin M
Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(14):5124-35.
1998: Blume-Jensen P; Janknecht R; Hunter T
The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136.
Current biology : CB 1998;8(13):779-82.
1998: Potter L R; Hunter T
Identification and characterization of the major phosphorylation sites of the B-type natriuretic peptide receptor.
The Journal of biological chemistry 1998;273(25):15533-9.
1998: Orend G; Hunter T; Ruoslahti E
Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells.
Oncogene 1998;16(20):2575-83.
1998: Schlaepfer D D; Jones K C; Hunter T
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events.
Molecular and cellular biology 1998;18(5):2571-85.
1998: Schlaepfer D D; Hunter T
Integrin signalling and tyrosine phosphorylation: just the FAKs?
Trends in cell biology 1998;8(4):151-7.
1998: Hunter T
The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1998;353(1368):583-605.
1998: Hunter T
Anti-phosphatases take the stage.
Nature genetics 1998;18(4):303-5.
1998: Potter L R; Hunter T
Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor.
Molecular and cellular biology 1998;18(4):2164-72.
1998: Poon R Y; Hunter T
Expression of a novel form of p21Cip1/Waf1 in UV-irradiated and transformed cells.
Oncogene 1998;16(10):1333-43.
1998: Jiang W; Hunter T
Analysis of cell-cycle profiles in transfected cells using a membrane-targeted GFP.
BioTechniques 1998;24(3):349-50, 352, 354.
1998: Sekiguchi T; Hunter T
Induction of growth arrest and cell death by overexpression of the cyclin-Cdk inhibitor p21 in hamster BHK21 cells.
Oncogene 1998;16(3):369-80.
1998: Hunter T
Prolyl isomerases and nuclear function.
Cell 1998;92(2):141-3.
1998: Majeti R; Bilwes A M; Noel J P; Hunter T; Weiss A
Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge.
Science (New York, N.Y.) 1998;279(5347):88-91.
1998: Hunter T
The role of tyrosine phosphorylation in cell growth and disease.
Harvey lectures 1998;94():81-119.
1997: Jiang W; Hunter T
Identification and characterization of a human protein kinase related to budding yeast Cdc7p.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14320-5.
1997: Shen M; Haggblom C; Vogt M; Hunter T; Lu K P
Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13618-23.
1997: Li S; Kim M; Hu Y L; Jalali S; Schlaepfer D D; Hunter T; Chien S; Shyy J Y
Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases.
The Journal of biological chemistry 1997;272(48):30455-62.
1997: Poon R Y; Chau M S; Yamashita K; Hunter T
The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells.
Cancer research 1997;57(22):5168-78.
1997: Sakamoto Y; Yoshida M; Semba K; Hunter T
Inhibition of the DNA-binding and transcriptional repression activity of the Wilms' tumor gene product, WT1, by cAMP-dependent protein kinase-mediated phosphorylation of Ser-365 and Ser-393 in the zinc finger domain.
Oncogene 1997;15(17):2001-12.
1997: Stein B; Yang M X; Young D B; Janknecht R; Hunter T; Murray B W; Barbosa M S
p38-2, a novel mitogen-activated protein kinase with distinct properties.
The Journal of biological chemistry 1997;272(31):19509-17.
1997: Fischer W H; Hoeger C A; Meisenhelder J; Hunter T; Craig A G
Determination of phosphorylation sites in peptides and proteins employing a volatile Edman reagent.
Journal of protein chemistry 1997;16(5):329-34.
1997: Ranganathan R; Lu K P; Hunter T; Noel J P
Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent.
Cell 1997;89(6):875-86.
1997: Schlaepfer D D; Hunter T
Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src.
The Journal of biological chemistry 1997;272(20):13189-95.
1997: Hunter T; Poon R Y
Cdc37: a protein kinase chaperone?
Trends in cell biology 1997;7(4):157-61.
1997: Fukunaga R; Hunter T
MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates.
The EMBO journal 1997;16(8):1921-33.
1997: Janknecht R; Hunter T
Convergence of MAP kinase pathways on the ternary complex factor Sap-1a.
The EMBO journal 1997;16(7):1620-7.
1997: Schlaepfer D D; Broome M A; Hunter T
Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins.
Molecular and cellular biology 1997;17(3):1702-13.
1997: Hunter T
Oncoprotein networks.
Cell 1997;88(3):333-46.
1997: Poon R Y; Lew J; Hunter T
Identification of functional domains in the neuronal Cdk5 activator protein.
The Journal of biological chemistry 1997;272(9):5703-8.
1997: Janknecht R; Hunter T
Activation of the Sap-1a transcription factor by the c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase.
The Journal of biological chemistry 1997;272(7):4219-24.
1997: Hunter T; Plowman G D
The protein kinases of budding yeast: six score and more.
Trends in biochemical sciences 1997;22(1):18-22.
1997: Broome M A; Hunter T
The PDGF receptor phosphorylates Tyr 138 in the c-Src SH3 domain in vivo reducing peptide ligand binding.
Oncogene 1997;14(1):17-34.
1996: Poon R Y; Toyoshima H; Hunter T
On the masking of signals on immunoblots by cellular proteins.
Journal of immunological methods 1996;199(2):155-8.
1996: Songyang Z; Lu K P; Kwon Y T; Tsai L H; Filhol O; Cochet C; Brickey D A; Soderling T R; Bartleson C; Graves D J; DeMaggio A J; Hoekstra M F; Blenis J; Hunter T; Cantley L C
A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.
Molecular and cellular biology 1996;16(11):6486-93.
1996: Schlaepfer D D; Hunter T
Signal transduction from the extracellular matrix--a role for the focal adhesion protein-tyrosine kinase FAK.
Cell structure and function 1996;21(5):445-50.
1996: Schlaepfer D D; Hunter T
Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases.
Molecular and cellular biology 1996;16(10):5623-33.
1996: Janknecht R; Hunter T
Transcription. A growing coactivator network.
Nature 1996;383(6595):22-3.
1996: Janknecht R; Hunter T
Versatile molecular glue. Transcriptional control.
Current biology : CB 1996;6(8):951-4.
1996: Bilwes A M; den Hertog J; Hunter T; Noel J P
Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization.
Nature 1996;382(6591):555-9.
1996: Hunter T
Solid-state protein networks?
Trends in cell biology 1996;6(7):254-5.
1996: Sekiguchi T; Noguchi E; Hayashida T; Nakashima T; Toyoshima H; Nishimoto T; Hunter T
D-type cyclin expression is decreased and p21 and p27 CDK inhibitor expression is increased when tsBN462 CCG1/TAFII250 mutant cells arrest in G1 at the restrictive temperature.
Genes to cells : devoted to molecular & cellular mechanisms 1996;1(7):687-705.
1996: Broome M A; Hunter T
Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling.
The Journal of biological chemistry 1996;271(28):16798-806.
1996: Winston L A; Hunter T
Intracellular signalling: putting JAKs on the kinase MAP.
Current biology : CB 1996;6(6):668-71.
1996: den Hertog J; Hunter T
Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains.
The EMBO journal 1996;15(12):3016-27.
1996: Hunter T
Tyrosine phosphorylation: past, present and future.
Biochemical Society transactions 1996;24(2):307-27.
1996: Poon R Y; Jiang W; Toyoshima H; Hunter T
Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage.
The Journal of biological chemistry 1996;271(22):13283-91.
1996: Fey M F; Moffat G J; Vik D P; Meisenhelder J; Saris C J; Hunter T; Tack B F
Complete structure of the murine p36 (annexin II) gene. Identification of mRNAs for both the murine and the human gene with alternatively spliced 5' noncoding exons.
Biochimica et biophysica acta 1996;1306(2-3):160-70.
1996: Gamper M; Howard P K; Hunter T; Firtel R A
Multiple roles of the novel protein tyrosine phosphatase PTP3 during Dictyostelium growth and development.
Molecular and cellular biology 1996;16(5):2431-44.
1996: Ezhevsky S A; Toyoshima H; Hunter T; Scott D W
Role of cyclin A and p27 in anti-IgM induced G1 growth arrest of murine B-cell lymphomas.
Molecular biology of the cell 1996;7(4):553-64.
1996: Lu K P; Hanes S D; Hunter T
A human peptidyl-prolyl isomerase essential for regulation of mitosis.
Nature 1996;380(6574):544-7.
1996: Mal A; Poon R Y; Howe P H; Toyoshima H; Hunter T; Harter M L
Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFbeta-treated cells.
Nature 1996;380(6571):262-5.
1996: Neet K; Hunter T
Vertebrate non-receptor protein-tyrosine kinase families.
Genes to cells : devoted to molecular & cellular mechanisms 1996;1(2):147-69.
1996: Fang F; Orend G; Watanabe N; Hunter T; Ruoslahti E
Dependence of cyclin E-CDK2 kinase activity on cell anchorage.
Science (New York, N.Y.) 1996;271(5248):499-502.
1996: Ofir R; Weinstein Y; Bazarsky E; Blagerman S; Wolfson M; Hunter T; Rager-Zisman B
Tyrosine phosphorylation of measles virus P-phosphoprotein in persistently infected neuroblastoma cells.
Virus genes 1996;13(3):203-10.
1995: Winston L A; Hunter T
JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone.
The Journal of biological chemistry 1995;270(52):30837-40.
1995: Poon R Y; Hunter T
Cell regulation. Innocent bystanders or chosen collaborators?
Current biology : CB 1995;5(11):1243-7.
1995: Haley A; Hunter T; Kiberstis P; Zimmern D
Multiple serine phosphorylation sites on the 30 kDa TMV cell-to-cell movement protein synthesized in tobacco protoplasts.
The Plant journal : for cell and molecular biology 1995;8(5):715-24.
1995: Poon R Y; Hunter T
Dephosphorylation of Cdk2 Thr160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin.
Science (New York, N.Y.) 1995;270(5233):90-3.
1995: Taylor S S; Radzio-Andzelm E; Hunter T
How do protein kinases discriminate between serine/threonine and tyrosine? Structural insights from the insulin receptor protein-tyrosine kinase.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(13):1255-66.
1995: Hunter T
When is a lipid kinase not a lipid kinase? When it is a protein kinase.
Cell 1995;83(1):1-4.
1995: Poon R Y; Toyoshima H; Hunter T
Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation.
Molecular biology of the cell 1995;6(9):1197-213.
1995: Neet K; Hunter T
The nonreceptor protein-tyrosine kinase CSK complexes directly with the GTPase-activating protein-associated p62 protein in cells expressing v-Src or activated c-Src.
Molecular and cellular biology 1995;15(9):4908-20.
1995: Karin M; Hunter T
Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus.
Current biology : CB 1995;5(7):747-57.
1995: Sekiguchi T; Nakashima T; Hayashida T; Kuraoka A; Hashimoto S; Tsuchida N; Shibata Y; Hunter T; Nishimoto T
Apoptosis is induced in BHK cells by the tsBN462/13 mutation in the CCG1/TAFII250 subunit of the TFIID basal transcription factor.
Experimental cell research 1995;218(2):490-8.
1995: Hanks S K; Hunter T
Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(8):576-96.
1995: Watanabe N; Broome M; Hunter T
Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle.
The EMBO journal 1995;14(9):1878-91.
1995: Lu K P; Hunter T
Evidence for a NIMA-like mitotic pathway in vertebrate cells.
Cell 1995;81(3):413-24.
1995: Tracy S; van der Geer P; Hunter T
The receptor-like protein-tyrosine phosphatase, RPTP alpha, is phosphorylated by protein kinase C on two serines close to the inner face of the plasma membrane.
The Journal of biological chemistry 1995;270(18):10587-94.
1995: Hunter T
Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling.
Cell 1995;80(2):225-36.
1995: Lu K P; Hunter T
The NIMA kinase: a mitotic regulator in Aspergillus nidulans and vertebrate cells.
Progress in cell cycle research 1995;1():187-205.
1994: Schlaepfer D D; Hanks S K; Hunter T; van der Geer P
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase.
Nature 1994;372(6508):786-91.
1994: Hunter T
1001 protein kinases redux--towards 2000.
Seminars in cell biology 1994;5(6):367-76.
1994: Hunter T; Pines J
Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age.
Cell 1994;79(4):573-82.
1994: Pines J; Hunter T
The differential localization of human cyclins A and B is due to a cytoplasmic retention signal in cyclin B.
The EMBO journal 1994;13(16):3772-81.
1994: Hoekstra M F; Dhillon N; Carmel G; DeMaggio A J; Lindberg R A; Hunter T; Kuret J
Budding and fission yeast casein kinase I isoforms have dual-specificity protein kinase activity.
Molecular biology of the cell 1994;5(8):877-86.
1994: Howard P K; Gamper M; Hunter T; Firtel R A
Regulation by protein-tyrosine phosphatase PTP2 is distinct from that by PTP1 during Dictyostelium growth and development.
Molecular and cellular biology 1994;14(8):5154-64.
1994: Toyoshima H; Hunter T
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21.
Cell 1994;78(1):67-74.
1994: Zhang S H; Broome M A; Lawton M A; Hunter T; Lamb C J
atpk1, a novel ribosomal protein kinase gene from Arabidopsis. II. Functional and biochemical analysis of the encoded protein.
The Journal of biological chemistry 1994;269(26):17593-9.
1994: Zhang S H; Lawton M A; Hunter T; Lamb C J
atpk1, a novel ribosomal protein kinase gene from Arabidopsis. I. Isolation, characterization, and expression.
The Journal of biological chemistry 1994;269(26):17586-92.
1994: den Hertog J; Tracy S; Hunter T
Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo.
The EMBO journal 1994;13(13):3020-32.
1994: Trautwein C; van der Geer P; Karin M; Hunter T; Chojkier M
Protein kinase A and C site-specific phosphorylations of LAP (NF-IL6) modulate its binding affinity to DNA recognition elements.
The Journal of clinical investigation 1994;93(6):2554-61.
1994: Rigaudy P; Simon S; Hunter T; Sollazzo M; Billetta R; Zanetti M; Eckhart W
Antibodies specific for the neuronal form of the Src protein elicited by an antigenized antibody.
DNA and cell biology 1994;13(6):585-91.
1994: van der Geer P; Hunter T
Phosphopeptide mapping and phosphoamino acid analysis by electrophoresis and chromatography on thin-layer cellulose plates.
Electrophoresis 1994;15(3-4):544-54.
1994: Kornbluth S; Sebastian B; Hunter T; Newport J
Membrane localization of the kinase which phosphorylates p34cdc2 on threonine 14.
Molecular biology of the cell 1994;5(3):273-82.
1994: Pawson T; Hunter T
Signal transduction and growth control in normal and cancer cells.
Current opinion in genetics & development 1994;4(1):1-4.
1994: Middlemas D S; Meisenhelder J; Hunter T
Identification of TrkB autophosphorylation sites and evidence that phospholipase C-gamma 1 is a substrate of the TrkB receptor.
The Journal of biological chemistry 1994;269(7):5458-66.
1994: van der Geer P; Hunter T; Lindberg R A
Receptor protein-tyrosine kinases and their signal transduction pathways.
Annual review of cell biology 1994;10():251-337.
1993: van der Geer P; Hunter T
Mutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts.
The EMBO journal 1993;12(13):5161-72.
1993: Hunter T
Braking the cycle.
Cell 1993;75(5):839-41.
1993: Hunter T
Signal transduction. Cytokine connections.
Nature 1993;366(6451):114-6.
1993: Trautwein C; Caelles C; van der Geer P; Hunter T; Karin M; Chojkier M
Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain.
Nature 1993;364(6437):544-7.
1993: Sebastian B; Kakizuka A; Hunter T
Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3521-4.
1993: O'Connor P M; Ferris D K; Pagano M; Draetta G; Pines J; Hunter T; Longo D L; Kohn K W
G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.
The Journal of biological chemistry 1993;268(11):8298-308.
1993: Merlio J P; Ernfors P; Kokaia Z; Middlemas D S; Bengzon J; Kokaia M; Smith M L; Siesjö B K; Hunter T; Lindvall O
Increased production of the TrkB protein tyrosine kinase receptor after brain insults.
Neuron 1993;10(2):151-64.
1993: Lindberg R A; Fischer W H; Hunter T
Characterization of a human protein threonine kinase isolated by screening an expression library with antibodies to phosphotyrosine.
Oncogene 1993;8(2):351-9.
1992: Meisenhelder J; Hunter T
The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment.
Molecular and cellular biology 1992;12(12):5843-56.
1992: Kikkawa U; Mann S K; Firtel R A; Hunter T
Molecular cloning of casein kinase II alpha subunit from Dictyostelium discoideum and its expression in the life cycle.
Molecular and cellular biology 1992;12(12):5711-23.
1992: Frisén J; Verge V M; Cullheim S; Persson H; Fried K; Middlemas D S; Hunter T; Hökfelt T; Risling M
Increased levels of trkB mRNA and trkB protein-like immunoreactivity in the injured rat and cat spinal cord.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11282-6.
1992: Lin A; Frost J; Deng T; Smeal T; al-Alawi N; Kikkawa U; Hunter T; Brenner D; Karin M
Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity.
Cell 1992;70(5):777-89.
1992: Krieg J; Hunter T
Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin.
The Journal of biological chemistry 1992;267(27):19258-65.
1992: Hunter T; Karin M
The regulation of transcription by phosphorylation.
Cell 1992;70(3):375-87.
1992: DeMaggio A J; Lindberg R A; Hunter T; Hoekstra M F
The budding yeast HRR25 gene product is a casein kinase I isoform.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):7008-12.
1992: Lock L F; Pines J; Hunter T; Gilbert D J; Gopalan G; Jenkins N A; Copeland N G; Donovan P J
A single cyclin A gene and multiple cyclin B1-related sequences are dispersed in the mouse genome.
Genomics 1992;13(2):415-24.
1992: Hamaguchi J R; Tobey R A; Pines J; Crissman H A; Hunter T; Bradbury E M
Requirement for p34cdc2 kinase is restricted to mitosis in the mammalian cdc2 mutant FT210.
The Journal of cell biology 1992;117(5):1041-53.
1992: Reedijk M; Liu X; van der Geer P; Letwin K; Waterfield M D; Hunter T; Pawson T
Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3'-kinase SH2 domains: a model for SH2-mediated receptor-target interactions.
The EMBO journal 1992;11(4):1365-72.
1992: Kakizuka A; Sebastian B; Borgmeyer U; Hermans-Borgmeyer I; Bolado J; Hunter T; Hoekstra M F; Evans R M
A mouse cdc25 homolog is differentially and developmentally expressed.
Genes & development 1992;6(4):578-90.
1992: Freed E; Hunter T
A 41-kilodalton protein is a potential substrate for the p210bcr-abl protein-tyrosine kinase in chronic myelogenous leukemia cells.
Molecular and cellular biology 1992;12(3):1312-23.
1992: Lindberg R A; Quinn A M; Hunter T
Dual-specificity protein kinases: will any hydroxyl do?
Trends in biochemical sciences 1992;17(3):114-9.
1992: Lu X P; Koch K S; Lew D J; Dulic V; Pines J; Reed S I; Hunter T; Leffert H L
Induction of cyclin mRNA and cyclin-associated histone H1 kinase during liver regeneration.
The Journal of biological chemistry 1992;267(5):2841-4.
1992: O'Connor P M; Ferris D K; White G A; Pines J; Hunter T; Longo D L; Kohn K W
Relationships between cdc2 kinase, DNA cross-linking, and cell cycle perturbations induced by nitrogen mustard.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992;3(1):43-52.
1992: Devoto S H; Mudryj M; Pines J; Hunter T; Nevins J R
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.
Cell 1992;68(1):167-76.
1992: Pines J; Hunter T
Cyclins A and B1 in the human cell cycle.
Ciba Foundation symposium 1992;170():187-96; discussion 196-204.
1992: Hunter T
Regulation of the eukaryotic cell cycle. Introduction.
Ciba Foundation symposium 1992;170():1-6.
1992: Hunter T; Lindberg R A; Middlemas D S; Tracy S; van der Geer P
Receptor protein tyrosine kinases and phosphatases.
Cold Spring Harbor symposia on quantitative biology 1992;57():25-41.
1991: Pines J; Hunter T
Cyclin-dependent kinases: a new cell cycle motif?
Trends in cell biology 1991;1(5):117-21.
1991: Pines J; Hunter T
Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport.
The Journal of cell biology 1991;115(1):1-17.
1991: Hunter T; Pines J
Cyclins and cancer.
Cell 1991;66(6):1071-4.
1991: van der Geer P; Hunter T
Tyrosine 706 and 807 phosphorylation site mutants in the murine colony-stimulating factor-1 receptor are unaffected in their ability to bind or phosphorylate phosphatidylinositol-3 kinase but show differential defects in their ability to induce early response gene transcription.
Molecular and cellular biology 1991;11(9):4698-709.
1991: Jähner D; Hunter T
The stimulation of quiescent rat fibroblasts by v-src and v-fps oncogenic protein-tyrosine kinases leads to the induction of a subset of immediate early genes.
Oncogene 1991;6(7):1259-68.
1991: Jähner D; Hunter T
The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts.
Molecular and cellular biology 1991;11(7):3682-90.
1991: Nishitani H; Ohtsubo M; Yamashita K; Iida H; Pines J; Yasudo H; Shibata Y; Hunter T; Nishimoto T
Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis.
The EMBO journal 1991;10(6):1555-64.
1991: Mudryj M; Devoto S H; Hiebert S W; Hunter T; Pines J; Nevins J R
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A.
Cell 1991;65(7):1243-53.
1991: Inoue J; Kerr L D; Ransone L J; Bengal E; Hunter T; Verma I M
c-rel activates but v-rel suppresses transcription from kappa B sites.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3715-9.
1991: Soppet D; Escandon E; Maragos J; Middlemas D S; Reid S W; Blair J; Burton L E; Stanton B R; Kaplan D R; Hunter T; Nikolics K; Parade L F
The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor.
Cell 1991;65(5):895-903.
1991: Hunter T
Protein-serine kinase receptors?
Current biology : CB 1991;1(1):15-6.
1991: Boyle W J; Smeal T; Defize L H; Angel P; Woodgett J R; Karin M; Hunter T
Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity.
Cell 1991;64(3):573-84.
1991: Hunter T
Cooperation between oncogenes.
Cell 1991;64(2):249-70.
1991: Middlemas D S; Lindberg R A; Hunter T
trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.
Molecular and cellular biology 1991;11(1):143-53.
1991: Meisenhelder J; Hunter T
Phosphorylation of phospholipase C in vivo and in vitro.
Methods in enzymology 1991;197():288-305.
1991: Boyle W J; van der Geer P; Hunter T
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates.
Methods in enzymology 1991;201():110-49.
1991: Pines J; Hunter T
Human cell division: the involvement of cyclins A and B1, and multiple cdc2s.
Cold Spring Harbor symposia on quantitative biology 1991;56():449-63.
1991: Nevins J R; Chellappan S P; Mudryj M; Hiebert S; Devoto S; Horowitz J; Hunter T; Pines J
E2F transcription factor is a target for the RB protein and the cyclin A protein.
Cold Spring Harbor symposia on quantitative biology 1991;56():157-62.
1991: Hunter T
Protein kinase classification.
Methods in enzymology 1991;200():3-37.
1990: Yamashita K; Yasuda H; Pines J; Yasumoto K; Nishitani H; Ohtsubo M; Hunter T; Sugimura T; Nishimoto T
Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells.
The EMBO journal 1990;9(13):4331-8.
1990: Lindberg R A; Hunter T
cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases.
Molecular and cellular biology 1990;10(12):6316-24.
1990: Bull P; Morley K L; Hoekstra M F; Hunter T; Verma I M
The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain.
Molecular and cellular biology 1990;10(10):5473-85.
1990: Pines J; Hunter T
Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.
Nature 1990;346(6286):760-3.
1990: Isacke C M; van der Geer P; Hunter T; Trowbridge I S
p180, a novel recycling transmembrane glycoprotein with restricted cell type expression.
Molecular and cellular biology 1990;10(6):2606-18.
1990: van der Geer P; Hunter T
Identification of tyrosine 706 in the kinase insert as the major colony-stimulating factor 1 (CSF-1)-stimulated autophosphorylation site in the CSF-1 receptor in a murine macrophage cell line.
Molecular and cellular biology 1990;10(6):2991-3002.
1990: Pines J; Hunter T
p34cdc2: the S and M kinase?
The New biologist 1990;2(5):389-401.
1990: Amiguet P; D'Eustachio P; Kristensen T; Wetsel R A; Saris C J; Hunter T; Chaplin D D; Tack B F
Structure and chromosome assignment of the murine p36 (calpactin I heavy chain) gene.
Biochemistry 1990;29(5):1226-32.
1990: Hunter T; Lindberg R A; Middlemas D S
Novel receptor protein-tyrosine kinases.
Advances in second messenger and phosphoprotein research 1990;24():260-5.
1989: Gould K L; Bretscher A; Esch F S; Hunter T
cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1.
The EMBO journal 1989;8(13):4133-42.
1989: Hunter T
Protein modification: phosphorylation on tyrosine residues.
Current opinion in cell biology 1989;1(6):1168-81.
1989: Bull P; Hunter T; Verma I M
Transcriptional induction of the murine c-rel gene with serum and phorbol-12-myristate-13-acetate in fibroblasts.
Molecular and cellular biology 1989;9(11):5239-43.
1989: Defize L H; Boonstra J; Meisenhelder J; Kruijer W; Tertoolen L G; Tilly B C; Hunter T; van Bergen en Henegouwen P M; Moolenaar W H; de Laat S W
Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors.
The Journal of cell biology 1989;109(5):2495-507.
1989: Freed E; Gailit J; van der Geer P; Ruoslahti E; Hunter T
A novel integrin beta subunit is associated with the vitronectin receptor alpha subunit (alpha v) in a human osteosarcoma cell line and is a substrate for protein kinase C.
The EMBO journal 1989;8(10):2955-65.
1989: Pines J; Hunter T
Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2.
Cell 1989;58(5):833-46.
1989: Hunter T
Protein-tyrosine phosphatases: the other side of the coin.
Cell 1989;58(6):1013-6.
1989: Meisenhelder J; Suh P G; Rhee S G; Hunter T
Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro.
Cell 1989;57(7):1109-22.
1989: Nunn M F; Hunter T
The ets sequence is required for induction of erythroblastosis in chickens by avian retrovirus E26.
Journal of virology 1989;63(1):398-402.
1989: Isacke C M; Lindberg R A; Hunter T
Synthesis of p36 and p35 is increased when U-937 cells differentiate in culture but expression is not inducible by glucocorticoids.
Molecular and cellular biology 1989;9(1):232-40.
1989: Gould K L; Bilezikjian L M; Hunter T
AtT20 cells express modified forms of pp60c-src.
Molecular endocrinology (Baltimore, Md.) 1989;3(1):79-88.
1989: Hunter T
The functions of oncogene products.
Progress in clinical and biological research 1989;288():25-34.
1988: Lindberg R A; Thompson D P; Hunter T
Identification of cDNA clones that code for protein-tyrosine kinases by screening expression libraries with antibodies against phosphotyrosine.
Oncogene 1988;3(6):629-33.
1988: Weinmaster G A; Hunter T
Investigation of the role of P130gag-fps in transformation: generation and use of a temperature-sensitive mutant P130gag-fps.
Journal of virology 1988;62(10):3849-54.
1988: Defize L H; Arndt-Jovin D J; Jovin T M; Boonstra J; Meisenhelder J; Hunter T; de Hey H T; de Laat S W
A431 cell variants lacking the blood group A antigen display increased high affinity epidermal growth factor-receptor number, protein-tyrosine kinase activity, and receptor turnover.
The Journal of cell biology 1988;107(3):939-49.
1988: Chiu R; Boyle W J; Meek J; Smeal T; Hunter T; Karin M
The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes.
Cell 1988;54(4):541-52.
1988: Gould K L; Hunter T
Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity.
Molecular and cellular biology 1988;8(8):3345-56.
1988: Hanks S K; Quinn A M; Hunter T
The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
Science (New York, N.Y.) 1988;241(4861):42-52.
1988: Weinmaster G A; Middlemas D S; Hunter T
A major site of tyrosine phosphorylation within the SH2 domain of Fujinami sarcoma virus P130gag-fps is not required for protein-tyrosine kinase activity or transforming potential.
Journal of virology 1988;62(6):2016-25.
1988: Cartwright C A; Simantov R; Cowan W M; Hunter T; Eckhart W
pp60c-src expression in the developing rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(10):3348-52.
1988: Angel P; Allegretto E A; Okino S T; Hattori K; Boyle W J; Hunter T; Karin M
Oncogene jun encodes a sequence-specific trans-activator similar to AP-1.
Nature 1988;332(6160):166-71.
1988: Hunter T; Angel P; Boyle W J; Chiu R; Freed E; Gould K L; Isacke C M; Karin M; Lindberg R A; van der Geer P
Targets for signal-transducing protein kinases.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():131-42.
1988: Hunter T
The Ca2+/phospholipid-binding proteins of the submembraneous skeleton.
Advances in experimental medicine and biology 1988;234():169-93.
1987: Hunter T
A thousand and one protein kinases.
Cell 1987;50(6):823-9.
1987: Bilezikjian L M; Woodgett J R; Hunter T; Vale W W
Phorbol ester-induced down-regulation of protein kinase C abolishes vasopressin-mediated responses in rat anterior pituitary cells.
Molecular endocrinology (Baltimore, Md.) 1987;1(8):555-60.
1987: Saris C J; Kristensen T; D'Eustachio P; Hicks L J; Noonan D J; Hunter T; Tack B F
cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (calpactin I).
The Journal of biological chemistry 1987;262(22):10663-71.
1987: Cartwright C A; Simantov R; Kaplan P L; Hunter T; Eckhart W
Alterations in pp60c-src accompany differentiation of neurons from rat embryo striatum.
Molecular and cellular biology 1987;7(5):1830-40.
1987: Woodgett J R; Hunter T
Isolation and characterization of two distinct forms of protein kinase C.
The Journal of biological chemistry 1987;262(10):4836-43.
1987: Hunter T
A tail of two src's: mutatis mutandis.
Cell 1987;49(1):1-4.
1987: Woodgett J R; Hunter T
Immunological evidence for two physiological forms of protein kinase C.
Molecular and cellular biology 1987;7(1):85-96.
1987: Woodgett J R; Hunter T
Regulation of protein kinase C by activators, Ca2+, and phosphorylation.
Progress in clinical and biological research 1987;249():237-47.
1986: Woodgett J R; Gould K L; Hunter T
Substrate specificity of protein kinase C. Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements.
European journal of biochemistry / FEBS 1986;161(1):177-84.
1986: Isacke C M; Meisenhelder J; Brown K D; Gould K L; Gould S J; Hunter T
Early phosphorylation events following the treatment of Swiss 3T3 cells with bombesin and the mammalian bombesin-related peptide, gastrin-releasing peptide.
The EMBO journal 1986;5(11):2889-98.
1986: Tripp M L; Piñon R; Meisenhelder J; Hunter T
Identification of phosphoproteins correlated with proliferation and cell cycle arrest in Saccharomyces cerevisiae: positive and negative regulation by cAMP-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(16):5973-7.
1986: Kristensen T; Saris C J; Hunter T; Hicks L J; Noonan D J; Glenney J R; Tack B F
Primary structure of bovine calpactin I heavy chain (p36), a major cellular substrate for retroviral protein-tyrosine kinases: homology with the human phospholipase A2 inhibitor lipocortin.
Biochemistry 1986;25(16):4497-503.
1986: Hunter T
Cancer. Cell growth control mechanisms.
Nature 1986;322(6074):14-6.
1986: Saris C J; Tack B F; Kristensen T; Glenney J R; Hunter T
The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.
Cell 1986;46(2):201-12.
1986: Isacke C M; Trowbridge I S; Hunter T
Modulation of p36 phosphorylation in human cells: studies using anti-p36 monoclonal antibodies.
Molecular and cellular biology 1986;6(7):2745-51.
1986: Gould K L; Woodgett J R; Isacke C M; Hunter T
The protein-tyrosine kinase substrate p36 is also a substrate for protein kinase C in vitro and in vivo.
Molecular and cellular biology 1986;6(7):2738-44.
1986: Patschinsky T; Hunter T; Sefton B M
Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virus.
Journal of virology 1986;59(1):73-81.
1986: Cartwright C A; Kaplan P L; Cooper J A; Hunter T; Eckhart W
Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen.
Molecular and cellular biology 1986;6(5):1562-70.
1986: Cooper J A; Gould K L; Cartwright C A; Hunter T
Tyr527 is phosphorylated in pp60c-src: implications for regulation.
Science (New York, N.Y.) 1986;231(4744):1431-4.
1986: Gould K L; Cooper J A; Bretscher A; Hunter T
The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein.
The Journal of cell biology 1986;102(2):660-9.
1986: Sefton B M; Hunter T
From c-src to v-src, or the case of the missing C terminus.
Cancer surveys 1986;5(2):159-72.
1985: Cooper J A; Hunter T
Major substrate for growth factor-activated protein-tyrosine kinases is a low-abundance protein.
Molecular and cellular biology 1985;5(11):3304-9.
1985: Gould K L; Woodgett J R; Cooper J A; Buss J E; Shalloway D; Hunter T
Protein kinase C phosphorylates pp60src at a novel site.
Cell 1985;42(3):849-57.
1985: Coussens P M; Cooper J A; Hunter T; Shalloway D
Restriction of the in vitro and in vivo tyrosine protein kinase activities of pp60c-src relative to pp60v-src.
Molecular and cellular biology 1985;5(10):2753-63.
1985: Hunter T
Cell-surface proteins. At last the insulin receptor.
Nature 1985;313(6005):740-1.
1985: Hunter T; Alexander C B; Cooper J A
Protein phosphorylation and growth control.
Ciba Foundation symposium 1985;116():188-204.
1985: Hunter T; Cooper J A
Protein-tyrosine kinases.
Annual review of biochemistry 1985;54():897-930.
1984: Voronova A F; Buss J E; Patschinsky T; Hunter T; Sefton B M
Characterization of the protein apparently responsible for the elevated tyrosine protein kinase activity in LSTRA cells.
Molecular and cellular biology 1984;4(12):2705-13.
1984: Kruijer W; Cooper J A; Hunter T; Verma I M
Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein.
Nature 1984;312(5996):711-6.
1984: Hunter T; Gould K L; Cooper J A
Tyrosine protein kinases, viral transformation and the control of cell proliferation.
Biochemical Society transactions 1984;12(5):757-9.
1984: Hunter T
Oncogenes and proto-oncogenes: how do they differ?
Journal of the National Cancer Institute 1984;73(4):773-86.
1984: Hunter T; Ling N; Cooper J A
Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane.
Nature 1984;311(5985):480-3.
1984: Hunter T
The epidermal growth factor receptor gene and its product.
Nature 1984;311(5985):414-6.
1984: Hunter T
The proteins of oncogenes.
Scientific American 1984;251(2):70-9.
1984: Cooper J A; Esch F S; Taylor S S; Hunter T
Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro.
The Journal of biological chemistry 1984;259(12):7835-41.
1984: Donoghue D J; Anderson C; Hunter T; Kaplan P L
Transmission of the polyoma virus middle T gene as the oncogene of a murine retrovirus.
Nature 1984;308(5961):748-50.
1984: Cochet C; Gill G N; Meisenhelder J; Cooper J A; Hunter T
C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.
The Journal of biological chemistry 1984;259(4):2553-8.
1984: Gould K L; Cooper J A; Hunter T
The 46,000-dalton tyrosine protein kinase substrate is widespread, whereas the 36,000-dalton substrate is only expressed at high levels in certain rodent tissues.
The Journal of cell biology 1984;98(2):487-97.
1984: Hunter T; Hutchinson M A; Eckhart W
Polyoma middle-sized T antigen can be phosphorylated on tyrosine at multiple sites in vitro.
The EMBO journal 1984;3(1):73-9.
1984: Cooper J A; Sefton B M; Hunter T
Diverse mitogenic agents induce the phosphorylation of two related 42,000-dalton proteins on tyrosine in quiescent chick cells.
Molecular and cellular biology 1984;4(1):30-7.
1984: Hunter T; Cooper J A
Tyrosine protein kinases and their substrates: an overview.
Advances in cyclic nucleotide and protein phosphorylation research 1984;17():443-55.
1984: Sefton B M; Hunter T
Tyrosine protein kinases.
Advances in cyclic nucleotide and protein phosphorylation research 1984;18():195-226.
1983: Cooper J A; Scolnick E M; Ozanne B; Hunter T
Epidermal growth factor receptor metabolism and protein kinase activity in human A431 cells infected with Snyder-Theilen feline sarcoma virus or harvey or Kirsten murine sarcoma virus.
Journal of virology 1983;48(3):752-64.
1983: Nigg E A; Cooper J A; Hunter T
Immunofluorescent localization of a 39,000-dalton substrate of tyrosine protein kinases to the cytoplasmic surface of the plasma membrane.
The Journal of cell biology 1983;96(6):1601-9.
1983: Cooper J; Nakamura K D; Hunter T; Weber M J
Phosphotyrosine-containing proteins and expression of transformation parameters in cells infected with partial transformation mutants of Rous sarcoma virus.
Journal of virology 1983;46(1):15-28.
1983: Papkoff J; Hunter T
Detection of an 85,000-dalton phosphoprotein in ts110 murine sarcoma virus-infected cells with antiserum against a v-mos peptide.
Journal of virology 1983;45(3):1177-82.
1983: Cooper J A; Reiss N A; Schwartz R J; Hunter T
Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus.
Nature 1983;302(5905):218-23.
1983: Hunter T; Jackson R; Zimmern D
Multiple proteins and subgenomic mRNAs may be derived from a single open reading frame on tobacco mosaic virus RNA.
Nucleic acids research 1983;11(3):801-21.
1983: Donoghue D J; Hunter T
Recombinational junctions of variants of Moloney murine sarcoma virus: generation and divergence of a mammalian transforming gene.
Journal of virology 1983;45(2):607-17.
1983: Cooper J A; Hunter T
Identification and characterization of cellular targets for tyrosine protein kinases.
The Journal of biological chemistry 1983;258(2):1108-15.
1983: Sefton B M; Hunter T; Cooper J A
Some lymphoid cell lines transformed by Abelson murine leukemia virus lack a major 36,000-dalton tyrosine protein kinase substrate.
Molecular and cellular biology 1983;3(1):56-63.
1983: Hunter T; Cooper J A
Role of tyrosine phosphorylation in malignant transformation by viruses and in cellular growth control.
Progress in nucleic acid research and molecular biology 1983;29():221-32.
1983: Cooper J A; Hunter T
Regulation of cell growth and transformation by tyrosine-specific protein kinases: the search for important cellular substrate proteins.
Current topics in microbiology and immunology 1983;107():125-61.
1983: Cooper J A; Sefton B M; Hunter T
Detection and quantification of phosphotyrosine in proteins.
Methods in enzymology 1983;99():387-402.
1982: Cooper J A; Bowen-Pope D F; Raines E; Ross R; Hunter T
Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins.
Cell 1982;31(1):263-73.
1982: Nigg E A; Sefton B M; Hunter T; Walter G; Singer S J
Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(17):5322-6.
1982: Adkins B; Hunter T
Two structurally and functionally different forms of the transforming protein of PRC II avian sarcoma virus.
Molecular and cellular biology 1982;2(8):890-6.
1982: Adkins B; Hunter T; Sefton B M
The transforming proteins of PRCII virus and Rous sarcoma virus form a complex with the same two cellular phosphoproteins.
Journal of virology 1982;43(2):448-55.
1982: Cooper J A; Hunter T
Discrete primary locations of a tyrosine-protein kinase and of three proteins that contain phosphotyrosine in virally transformed chick fibroblasts.
The Journal of cell biology 1982;94(2):287-96.
1982: Walter G; Hutchinson M A; Hunter T; Eckhart W
Purification of polyoma virus medium-size tumor antigen by immunoaffinity chromatography.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(13):4025-9.
1982: Papkoff J; Verma I M; Hunter T
Detection of a transforming gene product in cells transformed by Moloney murine sarcoma virus.
Cell 1982;29(2):417-26.
1982: Hunter T
Synthetic peptide substrates for a tyrosine protein kinase.
The Journal of biological chemistry 1982;257(9):4843-8.
1982: Donoghue D J; Hunter T
A generalized method of subcloning DNA fragments by restriction site reconstruction: application to sequencing the amino-terminal coding region of the transforming gene of Gazdar murine sarcoma virus.
Nucleic acids research 1982;10(8):2549-64.
1982: Adkins B; Hunter T; Beemon K
Expression of the PRC II avian sarcoma virus genome.
Journal of virology 1982;41(3):767-80.
1982: Sefton B M; Patschinsky T; Berdot C; Hunter T; Elliott T
Phosphorylation and metabolism of the transforming protein of Rous sarcoma virus.
Journal of virology 1982;41(3):813-20.
1982: Patschinsky T; Hunter T; Esch F S; Cooper J A; Sefton B M
Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(4):973-7.
1982: Donoghue D J; Hunter T
Expression of transforming region of Moloney murine sarcoma virus in Escherichia coli as a fusion protein with small tumor antigen of polyoma virus.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(3):800-4.
1982: Sefton B M; Hunter T; Nigg E A; Singer S J; Walter G
Cytoskeletal targets for viral transforming proteins with tyrosine protein kinase activity.
Cold Spring Harbor symposia on quantitative biology 1982;46 Pt 2():939-51.
1982: Papkoff J; Lai M H; Hunter T
Analysis of v-mos encoded proteins in cells transformed by several related murine sarcoma viruses.
Journal of cellular biochemistry 1982;19(4):349-62.
1981: Cooper J A; Hunter T
Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus.
The Journal of cell biology 1981;91(3 Pt 1):878-83.
1981: Papkoff J; Lai M H; Hunter T; Verma I M
Analysis of transforming gene products from Moloney murine sarcoma virus.
Cell 1981;27(1 Pt 2):109-19.
1981: Walter G; Hutchinson M A; Hunter T; Eckhart W
Antibodies specific for the polyoma virus middle-size tumor antigen.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(8):4882-6.
1981: Adkins B; Hunter T
Identification of a packaged cellular mRNA in virions of rous sarcoma virus.
Journal of virology 1981;39(2):471-80.
1981: Ali I U; Hunter T
Structural comparison of fibronectins from normal and transformed cells.
The Journal of biological chemistry 1981;256(14):7671-7.
1981: Hunter T; Cooper J A
Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells.
Cell 1981;24(3):741-52.
1981: Cooper J A; Hunter T
Four different classes of retroviruses induce phosphorylation of tyrosines present in similar cellular proteins.
Molecular and cellular biology 1981;1(5):394-407.
1981: Sefton B M; Hunter T; Ball E H; Singer S J
Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus.
Cell 1981;24(1):165-74.
1981: Sefton B M; Hunter T; Raschke W C
Evidence that the Abelson virus protein functions in vivo as a protein kinase that phosphorylates tyrosine.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(3):1552-6.
1981: Cooper J A; Hunter T
Changes in protein phosphorylation in Rous sarcoma virus-transformed chicken embryo cells.
Molecular and cellular biology 1981;1(2):165-78.
1980: Hunter T
Protein phosphorylated by the RSV transforming function.
Cell 1980;22(3):647-8.
1980: Mann K; Hunter T
Phosphorylation of SV40 large T antigen in SV40 nucleoprotein complexes.
Virology 1980;107(2):526-32.
1980: Sefton B M; Hunter T; Beemon K; Eckhart W
Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus.
Cell 1980;20(3):807-16.
1980: Sefton B M; Hunter T; Beemon K
Relationship of polypeptide products of the transforming gene of Rous sarcoma virus and the homologous gene of vertebrates.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(4):2059-63.
1980: Hunter T; Sefton B M
Transforming gene product of Rous sarcoma virus phosphorylates tyrosine.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(3):1311-5.
1980: Papkoff J; Hunter T; Beemon K
In vitro translation of virion RNA from Moloney murine sarcoma virus.
Virology 1980;101(1):91-103.
1980: Sefton B M; Hunter T; Beemon K
Temperature-sensitive transformation by Rous sarcoma virus and temperature-sensitive protein kinase activity.
Journal of virology 1980;33(1):220-9.
1980: Hunter T; Sefton B M; Beemon K
Studies on the structure and function of the avian sarcoma virus transforming-gene product.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 2,():931-41.
1980: Hunter T; Hutchinson M A; Eckhart W; Friedmann T; Esty A; La Porte P; Deininger P
Organization of T antigens in the polyoma virus genome.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 1,():131-9.
1979: Hunter T; Hutchinson M A; Eckhart W; Friedmann T; Esty A; LaPorte P; Deininger P
Regions of the polyoma genome coding for T antigens.
Nucleic acids research 1979;7(8):2275-88.
1979: Eckhart W; Hutchinson M A; Hunter T
An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates.
Cell 1979;18(4):925-33.
1979: Garrels J I; Hunter T
Post-translational modification of actins synthesized in vitro.
Biochimica et biophysica acta 1979;564(3):517-25.
1979: Lawrence C; Hunter T; Walter G
Characterization of the simian virus 40-specific messenger RNAs isolated from HeLa cells infected with the non-defective adenovirus 2-simian virus 40 hybrid viruses Ad2+ND2 and Ad2+ND4.
Journal of molecular biology 1979;134(1):95-108.
1979: Hunter T
Functional characterization of the early and late mRNAs of simian virus 40.
Virology 1979;95(2):511-22.
1979: Westphal H; Lai S P; Lawrence C; Hunter T; Walter G
Mosaic adenovirus-SV40 RNA specified by the non-defective hybrid virus Ad2+ND4.
Journal of molecular biology 1979;130(3):337-51.
1979: Sefton B M; Hunter T; Beemon K
Product of in vitro translation of the Rous sarcoma virus src gene has protein kinase activity.
Journal of virology 1979;30(1):311-8.
1979: Beemon K; Hunter T; Sefton B M
Polymorphism of avian sarcoma virus src proteins.
Journal of virology 1979;30(1):190-200.
1979: Linke H K; Hunter T; Walter G
Structural relationship between the 100,000- and 17,000- molecular-weight T antigens of simian virus 40 (SV40) as deduced by comparison with the SV40-specific proteins coded by the nondefective adenovirus type 2-SV40 hybrid viruses.
Journal of virology 1979;29(1):390-4.
1979: Mann K; Hunter T
Association of simian virus 40 T antigen with simian virus 40 nucleoprotein complexes.
Journal of virology 1979;29(1):232-41.
1978: Hunter T; Hutchinson M A; Eckhart W
Translation of polyoma virus T antigens in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(12):5917-21.
1978: Sefton B M; Beemon K; Hunter T
Comparison of the expression of the src gene of Rous sarcoma virus in vitro and in vivo.
Journal of virology 1978;28(3):957-71.
1978: Beemon K; Hunter T
Characterization of Rous sarcoma virus src gene products synthesized in vitro.
Journal of virology 1978;28(2):551-66.
1978: Hunter T; Gibson W
Characterization of the mRNA's for the polyoma virus capsid proteins VP1, VP2, and VP3.
Journal of virology 1978;28(1):240-53.
1978: Hutchinson M A; Hunter T; Eckhart W
Characterization of T antigens in polyoma-infected and transformed cells.
Cell 1978;15(1):65-77.
1977: Hunter T; Francke B; Bacheler L
In vitro polyoma DNA synthesis: asymmetry of short DNA chains.
Cell 1977;12(4):1021-8.
1977: Hunter T; Garrels J I
Characterization of the mRNAs for alpha-, beta- and gamma-actin.
Cell 1977;12(3):767-81.
1977: Mann K; Hunter T; Walter G; Linke H
Evidence for simian virus 40 (SV40) coding of SV40 T-antigen and the SV40-specific proteins in HeLa cells infected with nondefective adenovirus type 2-SV40 hybrid viruses.
Journal of virology 1977;24(1):151-69.
1977: Beemon K; Hunter T
In vitro translation yields a possible Rous sarcoma virus src gene product.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(8):3302-6.
1977: Gibson W; Hunter T; Cogen B; Eckhart W
Altered virion proteins of a temperature-sensitive mutant of polyoma virus, ts59.
Virology 1977;80(1):21-41.
1975: Hunter T; Francke B
In vitro polyoma DNA synthesis: inhibition by 1-beta-d-arabinofuranosyl CTP.
Journal of virology 1975;15(4):759-75.
1975: Francke B; Hunter T
In vitro polyoma DNA synthesis: requirement for cytoplasmic factors.
Journal of virology 1975;15(1):97-107.
1974: Francke B; Hunter T
In vitro polyoma DNA synthesis: discontinuous chain growth.
Journal of molecular biology 1974;83(1):99-121.
1974: Hunter T; Francke B
Letter: In vitro polyoma DNA synthesis: involvement of RNA in discontinuous chain growth.
Journal of molecular biology 1974;83(1):123-30.
1974: Francke B; Hunter T
In vitro polyoma DNA synthesis: studies on an early temperature-sensitive mutant.
Journal of virology 1974;13(1):241-3.
1974: Hunter T; Francke B
In vitro polyoma DNA synthesis: characterization of a system from infected 3T3 cells.
Journal of virology 1974;13(1):125-39.
1970: Jackson R; Hunter T
Role of methionine in the initiation of haemoglobin synthesis.
Nature 1970;227(5259):672-6.
1969: Hunter T; Munro A
Allelic variants in the amino-acid sequence of the alpha chain of rabbit haemoglobin.
Nature 1969;223(5212):1270-2.
1969: Hunt T; Hunter T; Munro A
Control of haemoglobin synthesis: rate of translation of the messenger RNA for the alpha and beta chains.
Journal of molecular biology 1969;43(1):123-33.

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