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Zachary Hunter

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Steve P Treon; Christina K Tripsas; Bryan Ciccarelli; Robert J Manning; Christopher J Patterson; Patricia Sheehy; Zachary R Hunter
Patients with waldenström macroglobulinemia commonly present with iron deficiency and those with severely depressed transferrin saturation levels show response to parenteral iron administration.
Lian Xu; Guang Yang; Yangsheng Zhou; Christina K Tripsas; Alessandra Trojani; Maria Varettoni; Kenneth C Anderson; Luca Arcaini; Jennifer R Brown; Yang Cao; Antonino Greco; Zachary R Hunter; Neal I Lindeman; Xia Liu; Robert J Manning; Enrica Morra; Nikhil C Munshi; Christopher J Patterson; Yu-Tzu Tai; Steve P Treon
MYD88 L265P in Waldenström macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele-specific polymerase chain reaction.
Steven P Treon; Christina Tripsas; Barry Turnbull; Christina Hanzis; Leukothea Ioakimidis; Robert J Manning; Christopher J Patterson; Patricia Sheehy; Zachary R Hunter
Familial disease predisposition impacts treatment outcome in patients with Waldenström macroglobulinemia.

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2013: Steve P Treon; Christina K Tripsas; Bryan Ciccarelli; Robert J Manning; Christopher J Patterson; Patricia Sheehy; Zachary R Hunter
Patients with waldenström macroglobulinemia commonly present with iron deficiency and those with severely depressed transferrin saturation levels show response to parenteral iron administration.
Clinical lymphoma, myeloma & leukemia 2013;13(2):241-3.
2013: Lian Xu; Guang Yang; Yangsheng Zhou; Christina K Tripsas; Alessandra Trojani; Maria Varettoni; Kenneth C Anderson; Luca Arcaini; Jennifer R Brown; Yang Cao; Antonino Greco; Zachary R Hunter; Neal I Lindeman; Xia Liu; Robert J Manning; Enrica Morra; Nikhil C Munshi; Christopher J Patterson; Yu-Tzu Tai; Steve P Treon
MYD88 L265P in Waldenström macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele-specific polymerase chain reaction.
Blood 2013;121(11):2051-8.
2012: Steven P Treon; Christina Tripsas; Barry Turnbull; Christina Hanzis; Leukothea Ioakimidis; Robert J Manning; Christopher J Patterson; Patricia Sheehy; Zachary R Hunter
Familial disease predisposition impacts treatment outcome in patients with Waldenström macroglobulinemia.
Clinical lymphoma, myeloma & leukemia 2012;12(6):433-7.
2012: Steve P Treon; Christina Tripsas; Lian Xu; Guang Yang; Yangsheng Zhou; Luca Arcaini; Yang Cao; Nancy Lee Harris; Jason M Laramie; Stephen E Lincoln; Xia Liu; Robert J Manning; Christopher J Patterson; Geraldine S Pinkus; Scott J Rodig; Patricia Sheehy; Donald A Skifter; Aliyah R Sohani; Zachary R Hunter
MYD88 L265P somatic mutation in Waldenström's macroglobulinemia.
The New England journal of medicine 2012;367(9):826-33.
2012: Rohit P Ojha; Christopher J Patterson; Patricia Sheehy; Karan P Singh; Christina K Tripsas; Philip S Brodsky; Sander Greenland; Christina A Hanzis; Zachary R Hunter; Leukothea Ioakimidis; Megan Lewicki; Robert J Manning; Tabatha N Offutt-Powell; Steven P Treon
Family history of non-hematologic cancers among Waldenstrom macroglobulinemia patients: a preliminary study.
Cancer epidemiology 2012;36(3):294-7.
2011: Jenny Y Sun; Hsiuyi Tseng; Lian Xu; Guang Yang; Yangsheng Zhou; Bangmin Zhu; Bryan Ciccarelli; Mariateresa Fulciniti; Ping Gong; Zachary R Hunter; Xia Liu; Kaveh Maghsoudi; Nikhil C Munshi; Christopher J Patterson; Steve P Treon
Vorinostat induced cellular stress disrupts the p38 mitogen activated protein kinase and extracellular signal regulated kinase pathways leading to apoptosis in Waldenström macroglobulinemia cells.
Leukemia & lymphoma 2011;52(9):1777-86.
2011: Steven P Treon; Christina Hanzis; Zachary R Hunter; Leukothea Ioakimidis; Robert J Manning; Christopher J Patterson; Patricia Sheehy; Barry Turnbull
Maintenance Rituximab is associated with improved clinical outcome in rituximab naïve patients with Waldenstrom Macroglobulinaemia who respond to a rituximab-containing regimen.
British journal of haematology 2011;154(3):357-62.
2011: Steven P Treon; Hsiuyi Tseng; Sigitas Verselis; Lian Xu; Guang Yang; Edward A Fox; Christine Hanzis; Zachary R Hunter; Leukothea Ioakimidis; Robert J Manning; Christopher J Patterson; Patricia Sheehy; Barry Turnbull
Attainment of complete/very good partial response following rituximab-based therapy is an important determinant to progression-free survival, and is impacted by polymorphisms in FCGR3A in Waldenstrom macroglobulinaemia.
British journal of haematology 2011;154(2):223-8.
2011: Yangsheng Zhou; Hsiuyi Tseng; Lian Xu; Guang Yang; Yang Cao; Bryan Ciccarelli; Zachary R Hunter; Jingrui Jiang; Xia Liu; Christopher J Patterson; Steve P Treon
Matrix metalloproteinase-8 is overexpressed in Waldenström's macroglobulinemia cells, and specific inhibition of this metalloproteinase blocks release of soluble CD27.
Clinical lymphoma, myeloma & leukemia 2011;11(1):172-5.
2011: Bryan Ciccarelli; Christopher J Patterson; Zachary R Hunter; Christina Hanzis; Leukothea Ioakimidis; Robert Manning; Guang Yang; Lian Xu; Yangsheng Zhou; Jenny Sun; Xia Liu; Hsiuyi Tseng; Yang Cao; Patricia Sheehy; Scott Rodig; Steve P Treon
Hepcidin is produced by lymphoplasmacytic cells and is associated with anemia in Waldenström's macroglobulinemia.
Clinical lymphoma, myeloma & leukemia 2011;11(1):160-3.
2011: Jenny Y Sun; Lian Xu; Hsuyi Tseng; Bryan Ciccarelli; Mariateresa Fulciniti; Zachary R Hunter; Kaveh Maghsoudi; Evdoxia Hatjiharissi; Yangsheng Zhou; Guang Yang; Biao Zhu; Xia Liu; P Gong; Leukothea Ioakimidis; Patricia Sheehy; Christopher J Patterson; Nikhil C Munshi; Owen A O'Connor; Steve P Treon
Histone deacetylase inhibitors demonstrate significant preclinical activity as single agents, and in combination with bortezomib in Waldenström's macroglobulinemia.
Clinical lymphoma, myeloma & leukemia 2011;11(1):152-6.
2011: Christina Hanzis; Rohit P Ojha; Zachary R Hunter; Robert Manning; Megan Lewicki; Philip Brodsky; Leukothea Ioakimidis; Christina Tripsas; Christopher J Patterson; Patricia Sheehy; Steve P Treon
Associated malignancies in patients with Waldenström's macroglobulinemia and their kin.
Clinical lymphoma, myeloma & leukemia 2011;11(1):88-92.
2010: Zachary R Hunter; Robert J Manning; Christine Hanzis; Bryan Ciccarelli; Leukothea Ioakimidis; Christopher J Patterson; Megan C Lewicki; Hsuiyi Tseng; Ping Gong; Xia Liu; Yangsheng Zhou; Guang Yang; Jenny Sun; Lian Xu; Patricia Sheehy; Massimo Morra; Steven P Treon
IgA and IgG hypogammaglobulinemia in Waldenström's macroglobulinemia.
Haematologica 2010;95(3):470-5.
2009: Xavier Leleu; Zachary R Hunter; Lian Xu; Aldo Roccaro; Anne-Sophie Moreau; Daniel D Santos; Evdoxia Hatjiharissi; Vinod Bakthavachalam; Sophia Adamia; Allen W Ho; Jacob Soumerai; Christopher J Patterson; Robert J Manning; Susanna Hamilton; Sigitas Verselis; Edward Fox; Ruben Carrasco; Irene M Ghobrial; Steve P Treon
Expression of regulatory genes for lymphoplasmacytic cell differentiation in Waldenstrom Macroglobulinemia.
British journal of haematology 2009;145(1):59-63.
2009: Xavier Leleu; Jérome Tamburini; Aldo Roccaro; Pierre Morel; Jacob Soumerai; Vincent Lévy; Mathieu Wemeau; Sandy Balkaran; Stephanie Poulain; Zachary R Hunter; Irene M Ghobrial; Steve P Treon; Veronique Leblond
Balancing risk versus benefit in the treatment of Waldenström's Macroglobulinemia patients with nucleoside analogue-based therapy.
Clinical lymphoma & myeloma 2009;9(1):71-3.
2009: Leukothea Ioakimidis; Christopher J Patterson; Zachary R Hunter; Jacob D Soumerai; Robert J Manning; Barry Turnbull; Patricia Sheehy; Steve P Treon
Comparative outcomes following CP-R, CVP-R, and CHOP-R in Waldenström's macroglobulinemia.
Clinical lymphoma & myeloma 2009;9(1):62-6.
2009: Xavier Leleu; Lian Xu; Xiaoying Jia; Antonio Sacco; Mena Farag; Zachary R Hunter; Anne-Sophie Moreau; Hai T Ngo; Evdoxia Hatjiharissi; Allen W Ho; Daniel Ditzel Santos; Sophia Adamia; Kelly O'Connor; Bryan Ciccarelli; Jacob Soumerai; Robert J Manning; Christopher J Patterson; Aldo Roccaro; Irene M Ghobrial; Steve P Treon
Endoplasmic reticulum stress is a target for therapy in Waldenstrom macroglobulinemia.
Blood 2009;113(3):626-34.
2009: Xavier Leleu; Jacob Soumerai; Aldo Roccaro; Evdoxia Hatjiharissi; Zachary R Hunter; Robert Manning; Bryan Ciccarelli; Antonio Sacco; Leukothea Ioakimidis; Sophia Adamia; Anne-Sophie Moreau; Christopher J Patterson; Irene M Ghobrial; Steve P Treon
Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenström macroglobulinemia treated with nucleoside analogs.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(2):250-5.
2009: Steve P Treon; Jacob D Soumerai; Andrew R Branagan; Zachary R Hunter; Christopher J Patterson; Leukothea Ioakimidis; Luis Chu; Paul Musto; Ari D Baron; Johannes C Nunnink; Joseph J Kash; Terenig O Terjanian; Paul M Hyman; Elena L Nawfel; David J Sharon; Nikhil C Munshi; Kenneth C Anderson
Lenalidomide and rituximab in Waldenstrom's macroglobulinemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(1):355-60.
2008: Steve P Treon; Jacob D Soumerai; Andrew R Branagan; Zachary R Hunter; Christopher J Patterson; Leukothea Ioakimidis; Frederick M Briccetti; Mark Pasmantier; Harvey Zimbler; Robert B Cooper; Maria Moore; John Hill; Alan Rauch; Lawrence Garbo; Luis Chu; Cynthia Chua; Stephen H Nantel; David R Lovett; Hans Boedeker; Henry Sonneborn; John Howard; Paul Musto; Bryan Ciccarelli; Evdoxia Hatjiharissi; Kenneth C Anderson
Thalidomide and rituximab in Waldenstrom macroglobulinemia.
Blood 2008;112(12):4452-7.
2008: Allen W Ho; Evdoxia Hatjiharissi; Bryan Ciccarelli; Andrew R Branagan; Zachary R Hunter; Xavier Leleu; Olivier Tournilhac; Lian Xu; Kelly O'Connor; Robert J Manning; Daniel Ditzel Santos; Mariana Chemaly; Christopher J Patterson; Jacob D Soumerai; Nikhil C Munshi; Julie A McEarchern; Che-Leung Law; Iqbal Grewal; Steve P Treon
CD27-CD70 interactions in the pathogenesis of Waldenstrom macroglobulinemia.
Blood 2008;112(12):4683-9.
2008: Anne-Sophie Moreau; Xiaoying Jia; Christopher J Patterson; Aldo Roccaro; Lian Xu; Antonio Sacco; Kelly O'Connor; Jacob Soumerai; Hai T Ngo; Evdoxia Hatjiharissi; Zachary R Hunter; Bryan Ciccarelli; Robert J Manning; Irene M Ghobrial; Xavier Leleu; Steve P Treon
The HMG-CoA inhibitor, simvastatin, triggers in vitro anti-tumour effect and decreases IgM secretion in Waldenstrom macroglobulinaemia.
British journal of haematology 2008;142(5):775-85.
2007: Evdoxia Hatjiharissi; Lian Xu; Daniel Ditzel Santos; Zachary R Hunter; Bryan Ciccarelli; Sigitas Verselis; Michael Modica; Yang Cao; Robert J Manning; Xavier Leleu; Elizabeth A Dimmock; Alexandros Kortsaris; Constantine S Mitsiades; Kenneth C Anderson; Edward A Fox; Steve P Treon
Increased natural killer cell expression of CD16, augmented binding and ADCC activity to rituximab among individuals expressing the Fc{gamma}RIIIa-158 V/V and V/F polymorphism.
Blood 2007;110(7):2561-4.
2007: Daniel Ditzel Santos; Allen W Ho; Olivier Tournilhac; Evdoxia Hatjiharissi; Xavier Leleu; Lian Xu; Pierfrancesco Tassone; Paola Neri; Zachary R Hunter; Mariana A Z Chemaly; Andrew R Branagan; Robert J Manning; Christopher J Patterson; Anne-Sophie Moreau; Bryan Ciccarelli; Sophia Adamia; Jitra Kriangkum; Jeffery L Kutok; Yu-Tzu Tai; Jiangwen Zhang; Linda M Pilarski; Kenneth C Anderson; Nikhil C Munshi; Steve P Treon
Establishment of BCWM.1 cell line for Waldenström's macroglobulinemia with productive in vivo engraftment in SCID-hu mice.
Experimental hematology 2007;35(9):1366-75.
2007: Steve P Treon; Evdoxia Hatjiharissi; Xavier Leleu; Anne-Sophie Moreau; Aldo Roccaro; Zachary R Hunter; Jacob D Soumerai; Bryan Ciccarelli; Lian Xu; Antonio Sacco; Hai T Ngo; Xiaoying Jia; Cao Yang; Sophia Adamia; Andrew R Branagan; Allen W Ho; Daniel Ditzel Santos; Olivier Tournilhac; Robert J Manning; Renee Leduc; Kelly O'Connor; Marybeth Nelson; Christopher J Patterson; Irene M Ghobrial
Novel agents in the treatment of Waldenström's macroglobulinemia.
Clinical lymphoma & myeloma 2007;7 Suppl 5():S199-206.
2007: Steve P Treon; Zachary R Hunter; Jeffrey Matous; Robin M Joyce; Brian Mannion; Ranjana Advani; David Cook; Joseph Songer; John Hill; Bruce R Kaden; David Sharon; Ronald Steiss; Xavier Leleu; Andrew R Branagan; Ashraf Badros
Multicenter clinical trial of bortezomib in relapsed/refractory Waldenstrom's macroglobulinemia: results of WMCTG Trial 03-248.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(11):3320-5.
2007: Evdoxia Hatjiharissi; Mark Hansen; Daniel Ditzel Santos; Lian Xu; Xavier Leleu; Elizabeth W Dimmock; Allen W Ho; Zachary R Hunter; Andrew R Branagan; Christopher J Patterson; Alexandros Kortsaris; Sigitas Verselis; Edward Fox; Steve P Treon
Genetic linkage of Fc gamma RIIa and Fc gamma RIIIa and implications for their use in predicting clinical responses to CD20-directed monoclonal antibody therapy.
Clinical lymphoma & myeloma 2007;7(4):286-90.
2007: Xavier Leleu; Kelly O'Connor; Allen W Ho; Daniel Ditzel Santos; Robert J Manning; Lian Xu; Evdoxia Hatjiharissi; Anne-Sophie Moreau; Andrew R Branagan; Zachary R Hunter; Elizabeth A Dimmock; Jacob Soumerai; Christopher Patterson; Irene M Ghobrial; Steve P Treon
Hepatitis C viral infection is not associated with Waldenström's macroglobulinemia.
American journal of hematology 2007;82(1):83-4.
2006: Marcel N Menke; Gilbert T Feke; J Wallace Mcmeel; Andrew R Branagan; Zachary R Hunter; Steve P Treon
Hyperviscosity-related retinopathy in waldenstrom macroglobulinemia.
Archives of ophthalmology 2006;124(11):1601-6.
2006: Olivier Tournilhac; Daniel Ditzel Santos; Lian Xu; Jeffery L Kutok; Yu-Tzu Tai; Steven Le Gouill; Laurence Catley; Zachary R Hunter; Andrew R Branagan; J A Boyce; Nikhil C Munshi; Kenneth C Anderson; Steve P Treon
Mast cells in Waldenstrom's macroglobulinemia support lymphoplasmacytic cell growth through CD154/CD40 signaling.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(8):1275-82.
2006: Daniel Ditzel Santos; Evdoxia Hatjiharissi; Olivier Tournilhac; Mariana Z A Chemaly; Xavier Leleu; Lian Xu; Christopher Patterson; Andrew R Branagan; Robert J Manning; Allen W Ho; Zachary R Hunter; Elizabeth A Dimmock; Jeffery L Kutok; Winthrop H Churchill; Mariana C Castells; Yu-Tzu Tai; Kenneth C Anderson; Steve P Treon
CD52 is expressed on human mast cells and is a potential therapeutic target in Waldenstrom's Macroglobulinemia and mast cell disorders.
Clinical lymphoma & myeloma 2006;6(6):478-83.
2006: Steve P Treon; Zachary R Hunter; A Aggarwal; E P Ewen; S Masota; C Lee; Daniel Ditzel Santos; Evdoxia Hatjiharissi; Lian Xu; Xavier Leleu; Olivier Tournilhac; Christopher J Patterson; Robert J Manning; Andrew R Branagan; C C Morton
Characterization of familial Waldenstrom's macroglobulinemia.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(3):488-94.
2005: Steve P Treon; Zachary R Hunter; Andrew R Barnagan
CHOP plus rituximab therapy in Waldenstrom's macroglobulinemia.
Clinical lymphoma 2005;5(4):273-7.
2005: Zachary R Hunter; Andrew R Branagan; Robert J Manning; Christopher J Patterson; Daniel Ditzel Santos; Olivier Tournilhac; David M Dorfman; Steve P Treon
CD5, CD10, and CD23 expression in Waldenstrom's macroglobulinemia.
Clinical lymphoma 2005;5(4):246-9.
2004: Steve P Treon; Olivier Tournilhac; Andrew R Branagan; Zachary R Hunter; Lian Xu; Evdoxia Hatjiharissi; Daniel Ditzel Santos
Clinical responses to sildenafil in Waldenstrom's macroglobulinemia.
Clinical lymphoma 2004;5(3):205-7.
2004: Steve P Treon; Andrew R Branagan; Zachary R Hunter; D Santos; O Tournhilac; Kenneth C Anderson
Paradoxical increases in serum IgM and viscosity levels following rituximab in Waldenstrom's macroglobulinemia.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(10):1481-3.