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Ed Hurt
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15
Tollervey, David
13
Simos, George
11
Bassler, Jochen
11
Petfalski, Elisabeth
10
Strässer, Katja
9
Mann, Matthias
7
Gadal, Olivier
7
Podtelejnikov, Alexandre
6
Ibrahim, El Chérif
6
Strauss, Daniela
6
Grosshans, Helge
6
Künzler, Markus
6
Katahira, Jun
5
Köhler, Alwin
5
Kressler, Dieter
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All Publications
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2009: Ulbrich Cornelia; Diepholz Meikel; Bassler Jochen; Kressler Dieter; Pertschy Brigitte; Galani Kyriaki; Böttcher Bettina; Hurt Ed
Mechanochemical removal of ribosome biogenesis factors from nascent 60S ribosomal subunits.
Cell 2009;138(5):911-22.
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2009: Flemming Dirk; Sarges Phillip; Stelter Philipp; Hellwig Andrea; Böttcher Bettina; Hurt Ed
Two structurally distinct domains of the nucleoporin Nup170 cooperate to tether a subset of nucleoporins to nuclear pores.
The Journal of cell biology 2009;185(3):387-95.
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2009: Klöckner Christoph; Schneider Maren; Lutz Sheila; Jani Divyang; Kressler Dieter; Stewart Murray; Hurt Ed; Köhler Alwin
Mutational uncoupling of the role of Sus1 in nuclear pore complex targeting of an mRNA export complex and histone H2B deubiquitination.
The Journal of biological chemistry 2009;284(18):12049-56.
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2009: Lacombe Thierry; García-Gómez Juan J; de la Cruz Jesús; Roser Daniela; Hurt Ed; Linder Patrick; Kressler Dieter
Linear ubiquitin fusion to Rps31 and its subsequent cleavage are required for the efficient production and functional integrity of 40S ribosomal subunits.
Molecular microbiology 2009;72(1):69-84.
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2009: Faza Marius Boulos; Kemmler Stefan; Jimeno Sonia; González-Aguilera Cristina; Aguilera Andrés; Hurt Ed; Panse Vikram Govind
Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery.
The Journal of cell biology 2009;184(6):833-46.
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2009: Katahira Jun; Inoue Hitomi; Hurt Ed; Yoneda Yoshihiro
Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA.
The EMBO journal 2009;28(5):556-67.
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2009: Skruzný Michal; Schneider Claudia; Rácz Attila; Weng Julan; Tollervey David; Hurt Ed
An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes.
PLoS biology 2009;7(1):e8.
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2009: Garrenton Lindsay S; Braunwarth Andreas; Irniger Stefan; Hurt Ed; Künzler Markus; Thorner Jeremy
Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence.
Molecular and cellular biology 2009;29(2):582-601.
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2008: Grund Stefanie E; Fischer Tamás; Cabal Ghislain G; Antúnez Oreto; Pérez-Ortín José E; Hurt Ed
The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression.
The Journal of cell biology 2008;182(5):897-910.
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2008: Beck Rainer; Sun Zhe; Adolf Frank; Rutz Chistoph; Bassler Jochen; Wild Klemens; Sinning Irmgard; Hurt Ed; Brügger Britta; Béthune Julien; Wieland Felix
Membrane curvature induced by Arf1-GTP is essential for vesicle formation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11731-6.
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2008: Kressler Dieter; Roser Daniela; Pertschy Brigitte; Hurt Ed
The AAA ATPase Rix7 powers progression of ribosome biogenesis by stripping Nsa1 from pre-60S particles.
The Journal of cell biology 2008;181(6):935-44.
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2008: Köhler Alwin; Schneider Maren; Cabal Ghislain G; Nehrbass Ulf; Hurt Ed
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export.
Nature cell biology 2008;10(6):707-15.
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2008: Schrader Nils; Stelter Philipp; Flemming Dirk; Kunze Ruth; Hurt Ed; Vetter Ingrid R
Structural basis of the nic96 subcomplex organization in the nuclear pore channel.
Molecular cell 2008;29(1):46-55.
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2008: Yao Wei; Lutzmann Malik; Hurt Ed
A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export.
The EMBO journal 2008;27(1):6-16.
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2007: Köhler Alwin; Hurt Ed
Exporting RNA from the nucleus to the cytoplasm.
Nature reviews. Molecular cell biology 2007;8(10):761-73.
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2007: Bradatsch Bettina; Katahira Jun; Kowalinski Eva; Bange Gert; Yao Wei; Sekimoto Toshihiro; Baumgärtel Viola; Boese Guido; Bassler Jochen; Wild Klemens; Peters Reiner; Yoneda Yoshihiro; Sinning Irmi; Hurt Ed
Arx1 functions as an unorthodox nuclear export receptor for the 60S preribosomal subunit.
Molecular cell 2007;27(5):767-79.
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2007: Kowalinski Eva; Bange Gert; Bradatsch Bettina; Hurt Ed; Wild Klemens; Sinning Irmgard
The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions.
FEBS letters 2007;581(23):4450-4.
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2007: Stelter Philipp; Kunze Ruth; Flemming Dirk; Höpfner Dominic; Diepholz Meikel; Philippsen Peter; Böttcher Bettina; Hurt Ed
Molecular basis for the functional interaction of dynein light chain with the nuclear-pore complex.
Nature cell biology 2007;9(7):788-96.
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2007: Panse Vikram Govind; Hurt Ed
Adjunct duties for karyopherins: regulating septin sumoylation.
Developmental cell 2007;12(5):669-70.
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2007: Yao Wei; Roser Daniela; Köhler Alwin; Bradatsch Bettina; Bassler Jochen; Hurt Ed
Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2.
Molecular cell 2007;26(1):51-62.
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2006: Panse Vikram Govind; Kressler Dieter; Pauli Andrea; Petfalski Elisabeth; Gnädig Marén; Tollervey David; Hurt Ed
Formation and nuclear export of preribosomes are functionally linked to the small-ubiquitin-related modifier pathway.
Traffic (Copenhagen, Denmark) 2006;7(10):1311-21.
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2006: Köhler Alwin; Pascual-García Pau; Llopis Ana; Zapater Meritxell; Posas Francesc; Hurt Ed; Rodríguez-Navarro Susana
The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11.
Molecular biology of the cell 2006;17(10):4228-36.
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2006: Bassler Jochen; Kallas Martina; Hurt Ed
The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles.
The Journal of biological chemistry 2006;281(34):24737-44.
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2006: Schäfer Thorsten; Maco Bohumil; Petfalski Elisabeth; Tollervey David; Böttcher Bettina; Aebi Ueli; Hurt Ed
Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit.
Nature 2006;441(7093):651-5.
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2005: Masuda Seiji; Das Rita; Cheng Hong; Hurt Ed; Dorman Nijsje; Reed Robin
Recruitment of the human TREX complex to mRNA during splicing.
Genes & development 2005;19(13):1512-7.
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2005: Lutzmann Malik; Kunze Ruth; Stangl Karin; Stelter Philipp; Tóth Katalin Fejes; Böttcher Bettina; Hurt Ed
Reconstitution of Nup157 and Nup145N into the Nup84 complex.
The Journal of biological chemistry 2005;280(18):18442-51.
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2005: Galani Kyriaki; Hurt Ed; Simos George
The tRNA aminoacylation co-factor Arc1p is excluded from the nucleus by an Xpo1p-dependent mechanism.
FEBS letters 2005;579(5):969-75.
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2004: Galani Kyriaki; Nissan T Amar; Petfalski Elisabeth; Tollervey David; Hurt Ed
Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits.
The Journal of biological chemistry 2004;279(53):55411-8.
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2004: Panse Vikram Govind; Hardeland Ulrike; Werner Thilo; Kuster Bernhard; Hurt Ed
A proteome-wide approach identifies sumoylated substrate proteins in yeast.
The Journal of biological chemistry 2004;279(40):41346-51.
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2004: Fischer Tamás; Rodríguez-Navarro Susana; Pereira Gislene; Rácz Attila; Schiebel Elmar; Hurt Ed
Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery.
Nature cell biology 2004;6(9):840-8.
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2004: Nissan Tracy A; Galani Kyriaki; Maco Bohumil; Tollervey David; Aebi Ueli; Hurt Ed
A pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits.
Molecular cell 2004;15(2):295-301.
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2004: Saracino Francesca; Bassler Jochen; Muzzini Diego; Hurt Ed; Agostoni Carbone Maria Luisa
The yeast kinase Swe1 is required for proper entry into cell cycle after arrest due to ribosome biogenesis and protein synthesis defects.
Cell cycle (Georgetown, Tex.) 2004;3(5):648-54.
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2004: Hurt Ed; Luo Ming-Juan; Röther Susanne; Reed Robin; Strässer Katja
Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):1858-62.
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2004: Rodríguez-Navarro Susana; Fischer Tamás; Luo Ming-Juan; Antúnez Oreto; Brettschneider Susanne; Lechner Johannes; Pérez-Ortín Jose E; Reed Robin; Hurt Ed
Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery.
Cell 2004;116(1):75-86.
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2003: Neumann Silvia; Petfalski Elisabeth; Brügger Britta; Grosshans Helge; Wieland Felix; Tollervey David; Hurt Ed
Formation and nuclear export of tRNA, rRNA and mRNA is regulated by the ubiquitin ligase Rsp5p.
EMBO reports 2003;4(12):1156-62.
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2003: Tschochner Herbert; Hurt Ed
Pre-ribosomes on the road from the nucleolus to the cytoplasm.
Trends in cell biology 2003;13(5):255-63.
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2003: Braunwarth Andreas; Fromont-Racine Micheline; Legrain Pierre; Bischoff F Ralf; Gerstberger Thomas; Hurt Ed; Kunzler Markus
Identification and characterization of a novel RanGTP-binding protein in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 2003;278(17):15397-405.
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2003: Schäfer Thorsten; Strauss Daniela; Petfalski Elisabeth; Tollervey David; Hurt Ed
The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes.
The EMBO journal 2003;22(6):1370-80.
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2003: Milkereit Philipp; Strauss Daniela; Bassler Jochen; Gadal Olivier; Kühn Holger; Schütz Sylvia; Gas Nicole; Lechner Johannes; Hurt Ed; Tschochner Herbert
A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits.
The Journal of biological chemistry 2003;278(6):4072-81.
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2003: Panse Vikram Govind; Küster Bernhard; Gerstberger Thomas; Hurt Ed
Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins.
Nature cell biology 2003;5(1):21-7.
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2002: Fischer Tamás; Strässer Katja; Rácz Attila; Rodriguez-Navarro Susana; Oppizzi Marisa; Ihrig Petra; Lechner Johannes; Hurt Ed
The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores.
The EMBO journal 2002;21(21):5843-52.
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2002: Nissan Tracy A; Bassler Jochen; Petfalski Elisabeth; Tollervey David; Hurt Ed
60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm.
The EMBO journal 2002;21(20):5539-47.
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2002: Grandi Paola; Rybin Vladimir; Bassler Jochen; Petfalski Elisabeth; Strauss Daniela; Marzioch Martina; Schäfer Thorsten; Kuster Bernhard; Tschochner Herbert; Tollervey David; Gavin Anne Claude; Hurt Ed
90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors.
Molecular cell 2002;10(1):105-15.
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2002: Gadal Olivier; Strauss Daniela; Petfalski Elisabeth; Gleizes Pierre-Emmanuel; Gas Nicole; Tollervey David; Hurt Ed
Rlp7p is associated with 60S preribosomes, restricted to the granular component of the nucleolus, and required for pre-rRNA processing.
The Journal of cell biology 2002;157(6):941-51.
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2002: Strässer Katja; Masuda Seiji; Mason Paul; Pfannstiel Jens; Oppizzi Marisa; Rodriguez-Navarro Susana; Rondón Ana G; Aguilera Andres; Struhl Kevin; Reed Robin; Hurt Ed
TREX is a conserved complex coupling transcription with messenger RNA export.
Nature 2002;417(6886):304-8.
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2002: Rodríguez-Navarro Susana; Strässer Katja; Hurt Ed
An intron in the YRA1 gene is required to control Yra1 protein expression and mRNA export in yeast.
EMBO reports 2002;3(5):438-42.
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2002: Katahira Jun; Straesser Katja; Saiwaki Takuya; Yoneda Yoshihiro; Hurt Ed
Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling.
The Journal of biological chemistry 2002;277(11):9242-6.
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2002: Reed Robin; Hurt Ed
A conserved mRNA export machinery coupled to pre-mRNA splicing.
Cell 2002;108(4):523-31.
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2002: Lutzmann Malik; Kunze Ruth; Buerer Andrea; Aebi Ueli; Hurt Ed
Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.
The EMBO journal 2002;21(3):387-97.
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2002: Simos George; Grosshans Helge; Hurt Ed
Nuclear export of tRNA.
Results and problems in cell differentiation 2002;35():115-31.
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2001: Senger B; Lafontaine D L; Graindorge J S; Gadal O; Camasses A; Sanni A; Garnier J M; Breitenbach M; Hurt E; Fasiolo F
The nucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis.
Molecular cell 2001;8(6):1363-73.
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2001: Bailer S M; Balduf C; Hurt E
The Nsp1p carboxy-terminal domain is organized into functionally distinct coiled-coil regions required for assembly of nucleoporin subcomplexes and nucleocytoplasmic transport.
Molecular and cellular biology 2001;21(23):7944-55.
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2001: Grosshans H; Lecointe F; Grosjean H; Hurt E; Simos G
Pus1p-dependent tRNA pseudouridinylation becomes essential when tRNA biogenesis is compromised in yeast.
The Journal of biological chemistry 2001;276(49):46333-9.
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2001: Strässer K; Hurt E
Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p.
Nature 2001;413(6856):648-52.
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2001: Künzler M; Hurt E
Targeting of Ran: variation on a common theme?
Journal of cell science 2001;114(Pt 18):3233-41.
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2001: Bassler J; Grandi P; Gadal O; Lessmann T; Petfalski E; Tollervey D; Lechner J; Hurt E
Identification of a 60S preribosomal particle that is closely linked to nuclear export.
Molecular cell 2001;8(3):517-29.
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2001: Gadal O; Strauss D; Braspenning J; Hoepfner D; Petfalski E; Philippsen P; Tollervey D; Hurt E
A nuclear AAA-type ATPase (Rix7p) is required for biogenesis and nuclear export of 60S ribosomal subunits.
The EMBO journal 2001;20(14):3695-704.
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2001: Milkereit P; Gadal O; Podtelejnikov A; Trumtel S; Gas N; Petfalski E; Tollervey D; Mann M; Hurt E; Tschochner H
Maturation and intranuclear transport of pre-ribosomes requires Noc proteins.
Cell 2001;105(4):499-509.
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2001: Grosshans H; Deinert K; Hurt E; Simos G
Biogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export.
The Journal of cell biology 2001;153(4):745-62.
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2001: Gadal O; Strauss D; Kessl J; Trumpower B; Tollervey D; Hurt E
Nuclear export of 60s ribosomal subunits depends on Xpo1p and requires a nuclear export sequence-containing factor, Nmd3p, that associates with the large subunit protein Rpl10p.
Molecular and cellular biology 2001;21(10):3405-15.
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2001: Künzler M; Trueheart J; Sette C; Hurt E; Thorner J
Mutations in the YRB1 gene encoding yeast ran-binding-protein-1 that impair nucleocytoplasmic transport and suppress yeast mating defects.
Genetics 2001;157(3):1089-105.
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2000: Hellmuth K; Grosjean H; Motorin Y; Deinert K; Hurt E; Simos G
Cloning and characterization of the Schizosaccharomyces pombe tRNA:pseudouridine synthase Pus1p.
Nucleic acids research 2000;28(23):4604-10.
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2000: Gomez-Ospina N; Morgan G; Giddings T H; Kosova B; Hurt E; Winey M
Yeast nuclear pore complex assembly defects determined by nuclear envelope reconstruction.
Journal of structural biology 2000;132(1):1-5.
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2000: Zhou Z; Luo M J; Straesser K; Katahira J; Hurt E; Reed R
The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans.
Nature 2000;407(6802):401-5.
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2000: Strässer K; Bassler J; Hurt E
Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export.
The Journal of cell biology 2000;150(4):695-706.
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2000: Bailer S M; Balduf C; Katahira J; Podtelejnikov A; Rollenhagen C; Mann M; Pante N; Hurt E
Nup116p associates with the Nup82p-Nsp1p-Nup159p nucleoporin complex.
The Journal of biological chemistry 2000;275(31):23540-8.
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2000: Künzler M; Gerstberger T; Stutz F; Bischoff F R; Hurt E
Yeast Ran-binding protein 1 (Yrb1) shuttles between the nucleus and cytoplasm and is exported from the nucleus via a CRM1 (XPO1)-dependent pathway.
Molecular and cellular biology 2000;20(12):4295-308.
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2000: Grosshans H; Simos G; Hurt E
Review: transport of tRNA out of the nucleus-direct channeling to the ribosome?
Journal of structural biology 2000;129(2-3):288-94.
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2000: Grosshans H; Hurt E; Simos G
An aminoacylation-dependent nuclear tRNA export pathway in yeast.
Genes & development 2000;14(7):830-40.
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2000: Siniossoglou S; Lutzmann M; Santos-Rosa H; Leonard K; Mueller S; Aebi U; Hurt E
Structure and assembly of the Nup84p complex.
The Journal of cell biology 2000;149(1):41-54.
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2000: Hurt E; Strässer K; Segref A; Bailer S; Schlaich N; Presutti C; Tollervey D; Jansen R
Mex67p mediates nuclear export of a variety of RNA polymerase II transcripts.
The Journal of biological chemistry 2000;275(12):8361-8.
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2000: Strässer K; Hurt E
Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export.
The EMBO journal 2000;19(3):410-20.
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2000: Lau D; Künzler M; Braunwarth A; Hellmuth K; Podtelejnikov A; Mann M; Hurt E
Purification of protein A-tagged yeast ran reveals association with a novel karyopherin beta family member, Pdr6p.
The Journal of biological chemistry 2000;275(1):467-71.
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2000: Kosova B; Panté N; Rollenhagen C; Podtelejnikov A; Mann M; Aebi U; Hurt E
Mlp2p, a component of nuclear pore attached intranuclear filaments, associates with nic96p.
The Journal of biological chemistry 2000;275(1):343-50.
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1999: Kosova B; Panté N; Rollenhagen C; Hurt E
Nup192p is a conserved nucleoporin with a preferential location at the inner site of the nuclear membrane.
The Journal of biological chemistry 1999;274(32):22646-51.
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1999: Strässer K; Hurt E
Nuclear RNA export in yeast.
FEBS letters 1999;452(1-2):77-81.
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1999: Katahira J; Strässer K; Podtelejnikov A; Mann M; Jung J U; Hurt E
The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human.
The EMBO journal 1999;18(9):2593-609.
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1999: Simos G; Hurt E
Transfer RNA biogenesis: A visa to leave the nucleus.
Current biology : CB 1999;9(7):R238-41.
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1999: Hurt E; Hannus S; Schmelzl B; Lau D; Tollervey D; Simos G
A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants.
The Journal of cell biology 1999;144(3):389-401.
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1998: Siniossoglou S; Santos-Rosa H; Rappsilber J; Mann M; Hurt E
A novel complex of membrane proteins required for formation of a spherical nucleus.
The EMBO journal 1998;17(22):6449-64.
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1998: Santos-Rosa H; Moreno H; Simos G; Segref A; Fahrenkrog B; Panté N; Hurt E
Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores.
Molecular and cellular biology 1998;18(11):6826-38.
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1998: Hellmuth K; Lau D M; Bischoff F R; Künzler M; Hurt E; Simos G
Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA.
Molecular and cellular biology 1998;18(11):6374-86.
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1998: Motorin Y; Keith G; Simon C; Foiret D; Simos G; Hurt E; Grosjean H
The yeast tRNA:pseudouridine synthase Pus1p displays a multisite substrate specificity.
RNA (New York, N.Y.) 1998;4(7):856-69.
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1998: Senger B; Simos G; Bischoff F R; Podtelejnikov A; Mann M; Hurt E
Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p.
The EMBO journal 1998;17(8):2196-207.
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1998: Bailer S M; Siniossoglou S; Podtelejnikov A; Hellwig A; Mann M; Hurt E
Nup116p and nup100p are interchangeable through a conserved motif which constitutes a docking site for the mRNA transport factor gle2p.
The EMBO journal 1998;17(4):1107-19.
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1997: Grandi P; Dang T; Pané N; Shevchenko A; Mann M; Forbes D; Hurt E
Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly.
Molecular biology of the cell 1997;8(10):2017-38.
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1997: Teixeira M T; Siniossoglou S; Podtelejnikov S; Bénichou J C; Mann M; Dujon B; Hurt E; Fabre E
Two functionally distinct domains generated by in vivo cleavage of Nup145p: a novel biogenesis pathway for nucleoporins.
The EMBO journal 1997;16(16):5086-97.
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1997: Segref A; Sharma K; Doye V; Hellwig A; Huber J; Lührmann R; Hurt E
Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores.
The EMBO journal 1997;16(11):3256-71.
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1997: Doye V; Hurt E
From nucleoporins to nuclear pore complexes.
Current opinion in cell biology 1997;9(3):401-11.
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1997: Fabre E; Hurt E
Yeast genetics to dissect the nuclear pore complex and nucleocytoplasmic trafficking.
Annual review of genetics 1997;31():277-313.
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