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Alvaro Acosta-Serrano

Research Profile

Chemicals & Drugs

Concepts & Ideas

Molecular Sequence Data

Procedures

Genes & Molecular Sequences

Phenomena

Glycosylation

Disorders

Trypanosomiasis, African

Physiology

Co-author Network

Publications

TOP 3
Naomi A Dyer; Nicholas O Ejeh; Clair Rose; Alvaro Acosta-Serrano
Flying tryps: survival and maturation of trypanosomes in tsetse flies.
Nicole Mideo; Sarah E Reece; Olivier Restif; Joanne P Webster; Alvaro Acosta-Serrano; Toni Aebischer; Mark J F Brown; Andy Fenton; Ville-Petri Friman; Sam P Brown
Life in cells, hosts, and vectors: parasite evolution across scales.
Robert Hirt; Yuk-Chien Liu; Sirintra Nakjang; Paola Rappelli; Alvaro Acosta-Serrano; Natalia de Miguel; Daniele Dessi; Nicia Diaz; Pier-Luigi Fiori; Jeremy C Mottram
Trichomonas vaginalis pathobiology new insights from the genome sequence.

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All Publications

2013: Naomi A Dyer; Nicholas O Ejeh; Clair Rose; Alvaro Acosta-Serrano
Flying tryps: survival and maturation of trypanosomes in tsetse flies.
Trends in parasitology 2013;29(4):188-96.
2013: Nicole Mideo; Sarah E Reece; Olivier Restif; Joanne P Webster; Alvaro Acosta-Serrano; Toni Aebischer; Mark J F Brown; Andy Fenton; Ville-Petri Friman; Sam P Brown
Life in cells, hosts, and vectors: parasite evolution across scales.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2013;13():344-7.
2011: Robert Hirt; Yuk-Chien Liu; Sirintra Nakjang; Paola Rappelli; Alvaro Acosta-Serrano; Natalia de Miguel; Daniele Dessi; Nicia Diaz; Pier-Luigi Fiori; Jeremy C Mottram
Trichomonas vaginalis pathobiology new insights from the genome sequence.
Advances in parasitology 2011;77():87-140.
2011: Jan Mani; Pascale Pescher; Alvaro Acosta-Serrano; Andreas Güttinger; Manfred Heller; Bernd Schimanski; Gerald Späth; Isabel Roditi
Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery.
PloS one 2011;6(7):e22463.
2010: Eleanor M Barnwell; Frederick J van Deursen; Laura Jeacock; Katherine A Smith; Rick M Maizels; Alvaro Acosta-Serrano; Keith Matthews
Developmental regulation and extracellular release of a VSG expression-site-associated gene product from Trypanosoma brucei bloodstream forms.
Journal of cell science 2010;123(Pt 19):3401-11.
2010: Peter Bütikofer; Eva Greganova; Yuk-Chien Liu; Ian J Edwards; Michael J Lehane; Alvaro Acosta-Serrano
Lipid remodelling of glycosylphosphatidylinositol (GPI) glycoconjugates in procyclic-form trypanosomes: biosynthesis and processing of GPIs revisited.
The Biochemical journal 2010;428(3):409-18.
2010: Eva Greganova; Peter Bütikofer; Alvaro Acosta-Serrano
The protease resistant surface (PRS) glycoconjugate from Trypanosoma congolense has an inositol-acylated glycosylphosphatidylinositol anchor, containing a significant proportion of myristate at the sn-2 position.
Molecular and biochemical parasitology 2010;171(1):50-4.
2009: Clarice S Clemmens; Meredith T Morris; Todd A Lyda; Alvaro Acosta-Serrano; James C Morris
Trypanosoma brucei AMP-activated kinase subunit homologs influence surface molecule expression.
Experimental parasitology 2009;123(3):250-7.
2009: Pegine Walrad; athina paterou; Alvaro Acosta-Serrano; Keith Matthews
Differential trypanosome surface coat regulation by a CCCH protein that co-associates with procyclin mRNA cis-elements.
PLoS pathogens 2009;5(2):e1000317.
2008: Sujatha Manthri; M Lucia S Güther; Luis Izquierdo; Alvaro Acosta-Serrano; Michael A J Ferguson
Deletion of the TbALG3 gene demonstrates site-specific N-glycosylation and N-glycan processing in Trypanosoma brucei.
Glycobiology 2008;18(5):367-83.
2006: M Lucia S Güther; Sylvia Lee; Laurence Tetley; Alvaro Acosta-Serrano; Michael A J Ferguson
GPI-anchored proteins and free GPI glycolipids of procyclic form Trypanosoma brucei are nonessential for growth, are required for colonization of the tsetse fly, and are not the only components of the surface coat.
Molecular biology of the cell 2006;17(12):5265-74.
2006: Silvia Utz; Isabel Roditi; Christina Kunz Renggli; Igor Almeida; Alvaro Acosta-Serrano; Peter Bütikofer
Trypanosoma congolense procyclins: unmasking cryptic major surface glycoproteins in procyclic forms.
Eukaryotic cell 2006;5(8):1430-40.
2005: Belinda S Hall; Arun Pal; David Goulding; Alvaro Acosta-Serrano; Mark Field
Trypanosoma brucei: TbRAB4 regulates membrane recycling and expression of surface proteins in procyclic forms.
Experimental parasitology 2005;111(3):160-71.
2005: Janine R Roper; M Lucia S Güther; James I Macrae; Alan R Prescott; Irene Hallyburton; Alvaro Acosta-Serrano; Michael A J Ferguson
The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number.
The Journal of biological chemistry 2005;280(20):19728-36.
2005: James I Macrae; Alvaro Acosta-Serrano; Nick A Morrice; Angela Mehlert; Michael A J Ferguson
Structural characterization of NETNES, a novel glycoconjugate in Trypanosoma cruzi epimastigotes.
The Journal of biological chemistry 2005;280(13):12201-11.
2004: Simone Leal; Alvaro Acosta-Serrano; James C Morris; George A M Cross
Transposon mutagenesis of Trypanosoma brucei identifies glycosylation mutants resistant to concanavalin A.
The Journal of biological chemistry 2004;279(28):28979-88.
2004: Kisaburo Nagamune; Alvaro Acosta-Serrano; Haruki Uemura; Reto Brun; Christina Kunz Renggli; Yusuke Maeda; Michael A J Ferguson; Taroh Kinoshita
Surface sialic acids taken from the host allow trypanosome survival in tsetse fly vectors.
The Journal of experimental medicine 2004;199(10):1445-50.
2004: Alvaro Acosta-Serrano; Jessica O'Rear; George Quellhorst; Soo Hee Lee; Kuo-Yuan Hwa; Sharon S Krag; Paul T Englund
Defects in the N-linked oligosaccharide biosynthetic pathway in a Trypanosoma brucei glycosylation mutant.
Eukaryotic cell 2004;3(2):255-63.
2003: Matthias Liniger; Alvaro Acosta-Serrano; Jan Van Den Abbeele; Christina Kunz Renggli; Reto Brun; Paul T Englund; Isabel Roditi
Cleavage of trypanosome surface glycoproteins by alkaline trypsin-like enzyme(s) in the midgut of Glossina morsitans.
International journal for parasitology 2003;33(12):1319-28.
2003: Peter Bütikofer; Jennifer Jelk; Tatiana Malherbe; Erik Vassella; Alvaro Acosta-Serrano; Christina Kunz Renggli; Reto Brun; Isabel Roditi
Phosphorylation of GPEET procyclin is not necessary for survival of Trypanosoma brucei procyclic forms in culture and in the tsetse fly midgut.
Molecular and biochemical parasitology 2003;126(2):287-91.
2001: Erik Vassella; Alvaro Acosta-Serrano; Erwin Studer; S H Lee; Paul T Englund; Isabel Roditi
Multiple procyclin isoforms are expressed differentially during the development of insect forms of Trypanosoma brucei.
Journal of molecular biology 2001;312(4):597-607.
2001: Simone Leal; Alvaro Acosta-Serrano; Y S Morita; Paul T Englund; Ulrike Böhme; George A M Cross
Virulence of Trypanosoma brucei strain 427 is not affected by the absence of glycosylphosphatidylinositol phospholipase C.
Molecular and biochemical parasitology 2001;114(2):245-7.
2001: Alvaro Acosta-Serrano; Igor Almeida; Lucio Freitas-Junior; N Yoshida; Sergio Schenkman
The mucin-like glycoprotein super-family of Trypanosoma cruzi: structure and biological roles.
Molecular and biochemical parasitology 2001;114(2):143-50.
2001: Alvaro Acosta-Serrano; Erik Vassella; Matthias Liniger; Christina Kunz Renggli; Reto Brun; Isabel Roditi; Paul T Englund
The surface coat of procyclic Trypanosoma brucei: programmed expression and proteolytic cleavage of procyclin in the tsetse fly.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1513-8.
2000: Alvaro Acosta-Serrano; Robert N Cole; Paul T Englund
Killing of Trypanosoma brucei by concanavalin A: structural basis of resistance in glycosylation mutants.
Journal of molecular biology 2000;304(4):633-44.
2000: YS Morita; Alvaro Acosta-Serrano; L U Buxbaum; Paul T Englund
Glycosyl phosphatidylinositol myristoylation in African trypanosomes. New intermediates in the pathway for fatty acid remodeling.
The Journal of biological chemistry 2000;275(19):14147-54.
2000: Vera Lucia Pereira-Chioccola; Alvaro Acosta-Serrano; I Correia de Almeida; Michael A J Ferguson; T Souto-Padron; Mauricio M Rodrigues; Luiz Travassos; Sergio Schenkman
Mucin-like molecules form a negatively charged coat that protects Trypanosoma cruzi trypomastigotes from killing by human anti-alpha-galactosyl antibodies.
Journal of cell science 2000;113 ( Pt 7)():1299-307.
1999: Alvaro Acosta-Serrano; Robert N Cole; Angela Mehlert; Min Goo Lee; Michael A J Ferguson; Paul T Englund
The procyclin repertoire of Trypanosoma brucei. Identification and structural characterization of the Glu-Pro-rich polypeptides.
The Journal of biological chemistry 1999;274(42):29763-71.
1999: Kuo-Yuan Hwa; Alvaro Acosta-Serrano; Kay-Hooi Khoo; Thomas A Pearson; Paul T Englund
Protein glycosylation mutants of procyclic Trypanosoma brucei: defects in the asparagine-glycosylation pathway.
Glycobiology 1999;9(2):181-90.
1997: R T Gazzinelli; M M Camargo; Igor Almeida; Y S Morita; M Giraldo; Alvaro Acosta-Serrano; S Hieny; Paul T Englund; Michael A J Ferguson; Luiz Travassos; A Sher
Identification and characterization of protozoan products that trigger the synthesis of IL-12 by inflammatory macrophages.
Chemical immunology 1997;68():136-52.